Helene Tronchere

Helene Tronchere

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Helene Tronchere

Helene Tronchere

Publications by authors named "Helene Tronchere"

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42Publications

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In vitro and in vivo cardioprotective and metabolic efficacy of vitamin E TPGS/Apelin.

J Mol Cell Cardiol 2020 Jan 10;138:165-174. Epub 2019 Dec 10.

INSERM U1048 I2MC, Toulouse, France; Université Paul Sabatier, Toulouse, France. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2019.12.001DOI Listing
January 2020

Metformin Protects the Heart Against Hypertrophic and Apoptotic Remodeling After Myocardial Infarction.

Front Pharmacol 2019 27;10:154. Epub 2019 Feb 27.

National Institute of Health and Medical Research (INSERM) U1048, Institute of Cardiovascular and Metabolic Diseases, Toulouse, France.

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http://dx.doi.org/10.3389/fphar.2019.00154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400884PMC
February 2019

Expression of myotubularins in blood platelets: Characterization and potential diagnostic of X-linked myotubular myopathy.

Biochem Biophys Res Commun 2016 07 4;476(3):167-73. Epub 2016 May 4.

INSERM, U1048 and Université Toulouse 3, Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Toulouse, France; CHU de Toulouse, Laboratoire d'Hématologie, Toulouse, France. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2016.04.127DOI Listing
July 2016

PI5P Triggers ICAM-1 Degradation in Shigella Infected Cells, Thus Dampening Immune Cell Recruitment.

Cell Rep 2016 Feb 14;14(4):750-759. Epub 2016 Jan 14.

INSERM U1048, I2MC and Université Paul Sabatier, 31432 Toulouse, France. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.12.079DOI Listing
February 2016

Phosphoinositides and cellular pathogens.

Subcell Biochem 2012 ;59:363-88

Inserm, U1048, Université Toulouse 3, I2MC, Hôpital de Toulouse, BP 84225 Avenue Jean Poulhès, 31432, Toulouse Cedex 04, France,

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http://dx.doi.org/10.1007/978-94-007-3015-1_12DOI Listing
January 2015

Phosphatidylinositol 5-phosphate: a nuclear stress lipid and a tuner of membranes and cytoskeleton dynamics.

Bioessays 2014 Mar 21;36(3):260-72. Epub 2013 Dec 21.

Inserm U1048, I2MC and Université Paul Sabatier, Toulouse, France.

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http://dx.doi.org/10.1002/bies.201300132DOI Listing
March 2014

A Shigella effector dampens inflammation by regulating epithelial release of danger signal ATP through production of the lipid mediator PtdIns5P.

Immunity 2013 Dec;39(6):1121-31

Inserm U786, Unité de Pathogénie Microbienne Moléculaire, 75724 Paris Cedex 15, France; Institut Pasteur, Unité de Pathogénie Microbienne Moléculaire, 75724 Paris Cedex 15, France. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2013.11.013DOI Listing
December 2013

The myotubularin-amphiphysin 2 complex in membrane tubulation and centronuclear myopathies.

EMBO Rep 2013 Oct 6;14(10):907-15. Epub 2013 Aug 6.

1] Department of Translational Medecine and Neurogenetics, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), 1 Rue Laurent Fries 67404, [2] INSERM, U964, [3] CNRS, UMR7104, [4] Université de Strasbourg, [5] Collège de France, chaire de génétique humaine, Illkirch, France.

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http://embor.embopress.org/cgi/doi/10.1038/embor.2013.119
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http://dx.doi.org/10.1038/embor.2013.119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807231PMC
October 2013

Phosphatase-dead myotubularin ameliorates X-linked centronuclear myopathy phenotypes in mice.

PLoS Genet 2012 11;8(10):e1002965. Epub 2012 Oct 11.

Department of Translational Medecine, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), INSERM U964, CNRS UMR7104, Université de Strasbourg, Collège de France, Illkirch, France.

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http://dx.doi.org/10.1371/journal.pgen.1002965DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469422PMC
March 2013

Genetic interaction between MTMR2 and FIG4 phospholipid phosphatases involved in Charcot-Marie-Tooth neuropathies.

PLoS Genet 2011 Oct 20;7(10):e1002319. Epub 2011 Oct 20.

Human Inherited Neuropathies Unit, INSPE-Institute for Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.1371/journal.pgen.1002319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197679PMC
October 2011

The nucleophosmin-anaplastic lymphoma kinase oncogene interacts, activates, and uses the kinase PIKfyve to increase invasiveness.

J Biol Chem 2011 Sep 7;286(37):32105-14. Epub 2011 Jul 7.

INSERM, U1048, I2MC, Université Toulouse III Paul-Sabatier, Centre Hospitalier Universitaire de Toulouse, Toulouse Cedex 4, France.

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http://dx.doi.org/10.1074/jbc.M111.227512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173219PMC
September 2011

Regulation and roles of PI3Kβ, a major actor in platelet signaling and functions.

Adv Enzyme Regul 2011 28;51(1):106-16. Epub 2010 Oct 28.

Inserm, U563, Université Toulouse III, Centre de Physiopathologie de Toulouse Purpan, CHU-Purpan, Toulouse, France.

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http://dx.doi.org/10.1016/j.advenzreg.2010.09.011DOI Listing
August 2011

Myotubularin controls desmin intermediate filament architecture and mitochondrial dynamics in human and mouse skeletal muscle.

J Clin Invest 2011 Jan 6;121(1):70-85. Epub 2010 Dec 6.

Department of Neurobiology and Genetics, Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France.

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http://dx.doi.org/10.1172/JCI44021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3007152PMC
January 2011

Evidence for a positive role of PtdIns5P in T-cell signal transduction pathways.

FEBS Lett 2010 Jun 24;584(11):2455-60. Epub 2010 Apr 24.

Institut National de la Santé et de la Recherche Médicale, Unité 891, Centre de Recherche en Cancérologie de Marseille, Marseille, France.

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http://dx.doi.org/10.1016/j.febslet.2010.04.051DOI Listing
June 2010

Cutting edge: Dok-1 and Dok-2 adaptor molecules are regulated by phosphatidylinositol 5-phosphate production in T cells.

J Immunol 2009 Apr;182(7):3974-8

Institut National de la Santé et de la Recherche Médicale, Centre de Recherche en Cancérologie de Marseille, France.

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http://dx.doi.org/10.4049/jimmunol.0804172DOI Listing
April 2009

Detection of myotubularin phosphatases activity on phosphoinositides in vitro and ex vivo.

Methods Mol Biol 2009 ;462:265-78

Department of Molecular Pathology, Institut de Génétique et de Biologie Moléculaire et Cellulaire, INSERM U596, CNRS UMR7104, Université Louis Pasteur de Strasbourg, Illkirch.

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http://dx.doi.org/10.1007/978-1-60327-115-8_18DOI Listing
February 2009

PtdIns5P: a little phosphoinositide with big functions?

Biochem Soc Symp 2007 (74):117-28

Inserm Unité 563, CPTP, Département d'Oncogenèse et Signalisation dans les Cellules Hématopoïétiques, IFR30, Hôpital Purpan, BP 3028 31024 Toulouse, France.

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http://dx.doi.org/10.1042/BSS0740117DOI Listing
July 2007

A novel PtdIns3P and PtdIns(3,5)P2 phosphatase with an inactivating variant in centronuclear myopathy.

Hum Mol Genet 2006 Nov 28;15(21):3098-106. Epub 2006 Sep 28.

Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Department of Molecular Pathology, Strasbourg, France.

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http://dx.doi.org/10.1093/hmg/ddl250DOI Listing
November 2006

PtdIns5P activates the host cell PI3-kinase/Akt pathway during Shigella flexneri infection.

EMBO J 2006 Mar 16;25(5):1024-34. Epub 2006 Feb 16.

INSERM Unité 563, CPTP, Département d'Oncogenèse et Signalisation dans les Cellules Hématopoiétiques, Hôpital Purpan, Toulouse, France.

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http://dx.doi.org/10.1038/sj.emboj.7601001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1409730PMC
March 2006

Emerging roles of phosphatidylinositol monophosphates in cellular signaling and trafficking.

Adv Enzyme Regul 2005 15;45:201-14. Epub 2005 Jul 15.

Inserm U563-CPTP, IFR 30, Department of Oncogenesis and signaling in haematopoïetic cells, CHU Purpan, 31024 Toulouse, France.

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http://dx.doi.org/10.1016/j.advenzreg.2005.02.006DOI Listing
February 2006

Integrin-dependent interaction of lipid rafts with the actin cytoskeleton in activated human platelets.

J Cell Sci 2005 Feb 25;118(Pt 4):759-69. Epub 2005 Jan 25.

Inserm U.563, Centre de Physiopathologie de Toulouse Purpan, Department of Oncogenesis and Signaling in Haematopoïetic Cells, IFR30, Hôpital Purpan, 31059 Toulouse, France.

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http://jcs.biologists.org/cgi/doi/10.1242/jcs.01648
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http://dx.doi.org/10.1242/jcs.01648DOI Listing
February 2005

Production of phosphatidylinositol 5-phosphate by the phosphoinositide 3-phosphatase myotubularin in mammalian cells.

J Biol Chem 2004 Feb 1;279(8):7304-12. Epub 2003 Dec 1.

INSERM U563, Département d'Oncogenèse et Signalisation dans les Cellules Hématopoïétiques, CPTP, IFR 30, Hôpital Purpan, 31059 Toulouse Cedex, France.

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http://dx.doi.org/10.1074/jbc.M311071200DOI Listing
February 2004

Phosphoinositide signaling disorders in human diseases.

FEBS Lett 2003 Jul;546(1):25-31

Inserm U563, Centre de Physiopathologie de Toulouse Purpan, Département d'oncogenèse et signalisation dans les cellules hématopoïétiques, Hôpital Purpan, 31059 Toulouse Cedex, France.

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http://dx.doi.org/10.1016/s0014-5793(03)00437-xDOI Listing
July 2003

Lipid rafts are critical membrane domains in blood platelet activation processes.

Biochim Biophys Acta 2003 Mar;1610(2):247-57

INSERM U563, Centre de Physiophatologie Toulouse Purpan, Département d'Oncogenèse et signalisation dans les cellules hématopoi;étiques, Hôpital Purpan 31059, Toulouse, France.

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http://dx.doi.org/10.1016/s0005-2736(03)00022-1DOI Listing
March 2003

Muscle-specific alternative splicing of myotubularin-related 1 gene is impaired in DM1 muscle cells.

Hum Mol Genet 2002 Sep;11(19):2297-307

Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, 1 rue Laurent Fries, BP 163, 67404 Illkirch Cedex, CU de Strasbourg, France.

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http://dx.doi.org/10.1093/hmg/11.19.2297DOI Listing
September 2002

Endosomal localization and function of sorting nexin 1.

Proc Natl Acad Sci U S A 2002 May 7;99(10):6767-72. Epub 2002 May 7.

Department of Medicine, University of California at San Diego School of Medicine, La Jolla, CA 92093-0650, USA.

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http://www.pnas.org/content/99/10/6767.full.pdf
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http://www.jstor.org/stable/pdf/3058740.pdf
Web Search
http://www.pnas.org/cgi/doi/10.1073/pnas.092142699
Publisher Site
http://dx.doi.org/10.1073/pnas.092142699DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC124477PMC
May 2002

Functional redundancy in the myotubularin family.

Biochem Biophys Res Commun 2002 Feb;291(2):305-12

Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Illkirch, C.U. de Strasbourg, France.

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http://dx.doi.org/10.1006/bbrc.2002.6445DOI Listing
February 2002