Publications by authors named "Helene Levaique"

16Publications

Cyclic bridged analogs of isoCA-4: Design, synthesis and biological evaluation.

Eur J Med Chem 2020 Oct 4;209:112873. Epub 2020 Oct 4.

Université Paris-Saclay, CNRS, BioCIS, 92290, Châtenay-Malabry, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2020.112873DOI Listing
October 2020

Synthesis and Anticancer Properties of Oxazepines Related to Azaisoerianin and IsoCoQuines.

ChemMedChem 2020 Jun 2. Epub 2020 Jun 2.

Université Paris-Saclay, CNRS, BioCIS, 92290, Châtenay-Malabry, France.

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http://dx.doi.org/10.1002/cmdc.202000197DOI Listing
June 2020

Identification of a new series of flavopiridol-like structures as kinase inhibitors with high cytotoxic potency.

Eur J Med Chem 2020 Aug 5;199:112355. Epub 2020 May 5.

BioCIS, Equipe Labellisée Ligue Contre le Cancer, Univ. Paris-Sud, CNRS, University Paris-Saclay, F-92290, Châtenay Malabry, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2020.112355DOI Listing
August 2020

Pyrrolo-imidazo[1,2-]pyridine Scaffolds through a Sequential Coupling of -Tosylhydrazones with Imidazopyridines and Reductive Cadogan Annulation, Synthetic Scope, and Application.

J Org Chem 2019 11 9;84(21):13807-13823. Epub 2019 Oct 9.

BioCIS UMR 8076, Université Paris-Sud, CNRS, Université Paris-Saclay, Equipe Labellisée Ligue Contre Le Cancer, Laboratoire de Chimie Thérapeutique, Faculté de Pharmacie , 5 rue J.-B. Clément , F-92296 Châtenay-Malabry , France.

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http://dx.doi.org/10.1021/acs.joc.9b02018DOI Listing
November 2019

N,N-bis-heteroaryl methylamines: Potent anti-mitotic and highly cytotoxic agents.

Eur J Med Chem 2019 Apr 16;168:176-188. Epub 2019 Feb 16.

BioCIS, Univ. Paris-Sud, CNRS, Université Paris-Saclay, 92290, Châtenay-Malabry, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2019.02.038DOI Listing
April 2019

1,1-Diheterocyclic Ethylenes Derived from Quinaldine and Carbazole as New Tubulin-Polymerization Inhibitors: Synthesis, Metabolism, and Biological Evaluation.

J Med Chem 2019 02 21;62(4):1902-1916. Epub 2018 Dec 21.

BioCIS, Université Paris-Sud, CNRS, Équipe Labellisée Ligue Contre le Cancer , Université Paris-Saclay , F-92290 Châtenay-Malabry , France.

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http://dx.doi.org/10.1021/acs.jmedchem.8b01386DOI Listing
February 2019

One-Pot Synthesis of 2-Styrylindoles from Ortho-Substituted Chloroenynes.

J Org Chem 2018 12 11;83(24):15323-15332. Epub 2018 Dec 11.

Univ. Paris-Sud, BioCIS, CNRS, University Paris-Saclay, Equipe Labellisée Ligue Contre Le Cancer, F-92296 Châtenay-Malabry , France.

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http://dx.doi.org/10.1021/acs.joc.8b02563DOI Listing
December 2018

Cytotoxic Prenylated Stilbenes Isolated from Macaranga tanarius.

J Nat Prod 2017 10 3;80(10):2684-2691. Epub 2017 Oct 3.

Institut de Chimie des Substances Naturelles, CNRS, ICSN UPR2301, University of Paris-Saclay , 91198, Gif-sur-Yvette, France.

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http://dx.doi.org/10.1021/acs.jnatprod.7b00409DOI Listing
October 2017

Palladium-Catalyzed One-Pot Reaction of Hydrazones, Dihaloarenes, and Organoboron Reagents: Synthesis and Cytotoxic Activity of 1,1-Diarylethylene Derivatives.

J Org Chem 2015 Jul 12;80(13):6715-27. Epub 2015 Jun 12.

†Université Paris-Sud, CNRS, BioCIS-UMR 8076, Equipe Labellisée Ligue Contre le Cancer, LabEx LERMIT, Laboratoire de Chimie Thérapeutique, Faculté de Pharmacie, rue J.-B. Clément, F-92296 Châtenay-Malabry, France.

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http://dx.doi.org/10.1021/acs.joc.5b00880DOI Listing
July 2015

Synthesis and biological evaluation of C-13' substituted 7'-homo-anhydrovinblastine derivatives.

Bioorg Med Chem Lett 2015 Apr 7;25(8):1771-1773. Epub 2015 Mar 7.

Centre de Recherche de Gif, Institut de Chimie des Substances Naturelles, UPR 2301 du CNRS, Avenue de la Terrasse, 91198 Gif-sur-Yvette Cedex, France. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2015.02.045DOI Listing
April 2015

Pipestelides A-C: cyclodepsipeptides from the Pacific marine sponge Pipestela candelabra.

J Nat Prod 2012 Apr 24;75(4):759-63. Epub 2012 Feb 24.

Centre de Recherche de Gif-sur-Yvette, Institut de Chimie des Substances Naturelles, UPR 2301, ICSN-CNRS, Avenue de la Terrasse, 91198 Gif-sur-Yvette, France.

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http://dx.doi.org/10.1021/np200714mDOI Listing
April 2012

Isolation, structure elucidation and biological activity of metabolites from Sch-642305-producing endophytic fungus Phomopsis sp. CMU-LMA.

Phytochemistry 2011 Dec 15;72(18):2406-12. Epub 2011 Sep 15.

Centre de Recherche de Gif, Institut de Chimie des Substances Naturelles ICSN, Centre National de la Recherche Scientifique, Gif-sur-Yvette, France.

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http://dx.doi.org/10.1016/j.phytochem.2011.08.010DOI Listing
December 2011

Biotransformation of natural compounds. Oxido-reduction of Sch-642305 by Aspergillus ochraceus ATCC 1009.

Bioorg Med Chem Lett 2011 Apr 18;21(8):2456-9. Epub 2011 Feb 18.

Centre de Recherche de Gif, Institut de Chimie des Substances Naturelles, C.N.R.S., Avenue de la Terrasse, 91198 Gif-sur-Yvette Cedex, France.

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http://dx.doi.org/10.1016/j.bmcl.2011.02.063DOI Listing
April 2011

ATP hydrolysis and pristinamycin IIA inhibition of the Staphylococcus aureus Vga(A), a dual ABC protein involved in streptogramin A resistance.

J Biol Chem 2008 Sep 18;283(37):25332-9. Epub 2008 Jun 18.

Institut de Chimie des Substances Naturelles, avenue de la Terrasse, Gif-sur-Yvette, France.

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http://dx.doi.org/10.1074/jbc.M800418200DOI Listing
September 2008