Publications by authors named "Helene Choquet"

42Publications

The Polygenic and Monogenic Basis of Blood Traits and Diseases.

Authors:
Dragana Vuckovic Erik L Bao Parsa Akbari Caleb A Lareau Abdou Mousas Tao Jiang Ming-Huei Chen Laura M Raffield Manuel Tardaguila Jennifer E Huffman Scott C Ritchie Karyn Megy Hannes Ponstingl Christopher J Penkett Patrick K Albers Emilie M Wigdor Saori Sakaue Arden Moscati Regina Manansala Ken Sin Lo Huijun Qian Masato Akiyama Traci M Bartz Yoav Ben-Shlomo Andrew Beswick Jette Bork-Jensen Erwin P Bottinger Jennifer A Brody Frank J A van Rooij Kumaraswamy N Chitrala Peter W F Wilson Hélène Choquet John Danesh Emanuele Di Angelantonio Niki Dimou Jingzhong Ding Paul Elliott Tõnu Esko Michele K Evans Stephan B Felix James S Floyd Linda Broer Niels Grarup Michael H Guo Qi Guo Andreas Greinacher Jeff Haessler Torben Hansen Joanna M M Howson Wei Huang Eric Jorgenson Tim Kacprowski Mika Kähönen Yoichiro Kamatani Masahiro Kanai Savita Karthikeyan Fotios Koskeridis Leslie A Lange Terho Lehtimäki Allan Linneberg Yongmei Liu Leo-Pekka Lyytikäinen Ani Manichaikul Koichi Matsuda Karen L Mohlke Nina Mononen Yoshinori Murakami Girish N Nadkarni Kjell Nikus Nathan Pankratz Oluf Pedersen Michael Preuss Bruce M Psaty Olli T Raitakari Stephen S Rich Benjamin A T Rodriguez Jonathan D Rosen Jerome I Rotter Petra Schubert Cassandra N Spracklen Praveen Surendran Hua Tang Jean-Claude Tardif Mohsen Ghanbari Uwe Völker Henry Völzke Nicholas A Watkins Stefan Weiss Na Cai Kousik Kundu Stephen B Watt Klaudia Walter Alan B Zonderman Kelly Cho Yun Li Ruth J F Loos Julian C Knight Michel Georges Oliver Stegle Evangelos Evangelou Yukinori Okada David J Roberts Michael Inouye Andrew D Johnson Paul L Auer William J Astle Alexander P Reiner Adam S Butterworth Willem H Ouwehand Guillaume Lettre Vijay G Sankaran Nicole Soranzo

Cell 2020 Sep;182(5):1214-1231.e11

Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, UK; National Institute for Health Research Blood and Transplant Research Unit (NIHR BTRU) in Donor Health and Genomics, University of Cambridge, Cambridge, CB1 8RN, UK; British Heart Foundation Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK; Department of Haematology, University of Cambridge, Cambridge, CB2 0PT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2020.08.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482360PMC
September 2020

Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.

Authors:
Ming-Huei Chen Laura M Raffield Abdou Mousas Saori Sakaue Jennifer E Huffman Arden Moscati Bhavi Trivedi Tao Jiang Parsa Akbari Dragana Vuckovic Erik L Bao Xue Zhong Regina Manansala Véronique Laplante Minhui Chen Ken Sin Lo Huijun Qian Caleb A Lareau Mélissa Beaudoin Karen A Hunt Masato Akiyama Traci M Bartz Yoav Ben-Shlomo Andrew Beswick Jette Bork-Jensen Erwin P Bottinger Jennifer A Brody Frank J A van Rooij Kumaraswamynaidu Chitrala Kelly Cho Hélène Choquet Adolfo Correa John Danesh Emanuele Di Angelantonio Niki Dimou Jingzhong Ding Paul Elliott Tõnu Esko Michele K Evans James S Floyd Linda Broer Niels Grarup Michael H Guo Andreas Greinacher Jeff Haessler Torben Hansen Joanna M M Howson Qin Qin Huang Wei Huang Eric Jorgenson Tim Kacprowski Mika Kähönen Yoichiro Kamatani Masahiro Kanai Savita Karthikeyan Fotis Koskeridis Leslie A Lange Terho Lehtimäki Markus M Lerch Allan Linneberg Yongmei Liu Leo-Pekka Lyytikäinen Ani Manichaikul Hilary C Martin Koichi Matsuda Karen L Mohlke Nina Mononen Yoshinori Murakami Girish N Nadkarni Matthias Nauck Kjell Nikus Willem H Ouwehand Nathan Pankratz Oluf Pedersen Michael Preuss Bruce M Psaty Olli T Raitakari David J Roberts Stephen S Rich Benjamin A T Rodriguez Jonathan D Rosen Jerome I Rotter Petra Schubert Cassandra N Spracklen Praveen Surendran Hua Tang Jean-Claude Tardif Richard C Trembath Mohsen Ghanbari Uwe Völker Henry Völzke Nicholas A Watkins Alan B Zonderman Peter W F Wilson Yun Li Adam S Butterworth Jean-François Gauchat Charleston W K Chiang Bingshan Li Ruth J F Loos William J Astle Evangelos Evangelou David A van Heel Vijay G Sankaran Yukinori Okada Nicole Soranzo Andrew D Johnson Alexander P Reiner Paul L Auer Guillaume Lettre

Cell 2020 Sep;182(5):1198-1213.e14

Montreal Heart Institute, Montreal, QC H1T 1C8, Canada; Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, QC H3T 1J4, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2020.06.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480402PMC
September 2020

Meta-Analysis of 26 638 Individuals Identifies Two Genetic Loci Associated With Left Ventricular Ejection Fraction.

Circ Genom Precis Med 2020 Aug 30;13(4):e002804. Epub 2020 Jun 30.

Division of Research, Kaiser Permanente Northern California (KPNC), Oakland, CA (H.C., K.K.T., C.J., D.K.R., A.S.G., N.R., C.S.).

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http://dx.doi.org/10.1161/CIRCGEN.119.002804DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446727PMC
August 2020

Genome-wide Genotyping of Cerebral Cavernous Malformation Type 1 Individuals to Identify Genetic Modifiers of Disease Severity.

Methods Mol Biol 2020 ;2152:77-84

Department of Anesthesia and Perioperative Care, School of Medicine, University of California San Francisco (UCSF), San Francisco, CA, USA.

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http://dx.doi.org/10.1007/978-1-0716-0640-7_6DOI Listing
January 2020

Genetic and environmental factors underlying keratinocyte carcinoma risk.

JCI Insight 2020 05 21;5(10). Epub 2020 May 21.

Kaiser Permanente Northern California, Division of Research, Oakland, California, USA.

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http://dx.doi.org/10.1172/jci.insight.134783DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259534PMC
May 2020

Functional validity, role, and implications of heavy alcohol consumption genetic loci.

Sci Adv 2020 01 15;6(3):eaay5034. Epub 2020 Jan 15.

Wolfson Centre for Personalised Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1126/sciadv.aay5034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962045PMC
January 2020

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations.

PLoS Genet 2019 12 23;15(12):e1008500. Epub 2019 Dec 23.

Department of Biostatistics, University of North Carolina, Chapel Hill, North Carolina, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1008500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953885PMC
December 2019

Contribution of rare coding mutations in CD36 to type 2 diabetes and cardio-metabolic complications.

Sci Rep 2019 11 20;9(1):17123. Epub 2019 Nov 20.

Centre for Cell Biology and Cutaneous Research, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.

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http://dx.doi.org/10.1038/s41598-019-53388-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868229PMC
November 2019

Clinical implications of recent advances in primary open-angle glaucoma genetics.

Eye (Lond) 2020 01 23;34(1):29-39. Epub 2019 Oct 23.

NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.

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http://dx.doi.org/10.1038/s41433-019-0632-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002426PMC
January 2020

Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.

Authors:
Mengzhen Liu Yu Jiang Robbee Wedow Yue Li David M Brazel Fang Chen Gargi Datta Jose Davila-Velderrain Daniel McGuire Chao Tian Xiaowei Zhan Hélène Choquet Anna R Docherty Jessica D Faul Johanna R Foerster Lars G Fritsche Maiken Elvestad Gabrielsen Scott D Gordon Jeffrey Haessler Jouke-Jan Hottenga Hongyan Huang Seon-Kyeong Jang Philip R Jansen Yueh Ling Reedik Mägi Nana Matoba George McMahon Antonella Mulas Valeria Orrù Teemu Palviainen Anita Pandit Gunnar W Reginsson Anne Heidi Skogholt Jennifer A Smith Amy E Taylor Constance Turman Gonneke Willemsen Hannah Young Kendra A Young Gregory J M Zajac Wei Zhao Wei Zhou Gyda Bjornsdottir Jason D Boardman Michael Boehnke Dorret I Boomsma Chu Chen Francesco Cucca Gareth E Davies Charles B Eaton Marissa A Ehringer Tõnu Esko Edoardo Fiorillo Nathan A Gillespie Daniel F Gudbjartsson Toomas Haller Kathleen Mullan Harris Andrew C Heath John K Hewitt Ian B Hickie John E Hokanson Christian J Hopfer David J Hunter William G Iacono Eric O Johnson Yoichiro Kamatani Sharon L R Kardia Matthew C Keller Manolis Kellis Charles Kooperberg Peter Kraft Kenneth S Krauter Markku Laakso Penelope A Lind Anu Loukola Sharon M Lutz Pamela A F Madden Nicholas G Martin Matt McGue Matthew B McQueen Sarah E Medland Andres Metspalu Karen L Mohlke Jonas B Nielsen Yukinori Okada Ulrike Peters Tinca J C Polderman Danielle Posthuma Alexander P Reiner John P Rice Eric Rimm Richard J Rose Valgerdur Runarsdottir Michael C Stallings Alena Stančáková Hreinn Stefansson Khanh K Thai Hilary A Tindle Thorarinn Tyrfingsson Tamara L Wall David R Weir Constance Weisner John B Whitfield Bendik Slagsvold Winsvold Jie Yin Luisa Zuccolo Laura J Bierut Kristian Hveem James J Lee Marcus R Munafò Nancy L Saccone Cristen J Willer Marilyn C Cornelis Sean P David David A Hinds Eric Jorgenson Jaakko Kaprio Jerry A Stitzel Kari Stefansson Thorgeir E Thorgeirsson Gonçalo Abecasis Dajiang J Liu Scott Vrieze

Nat Genet 2019 02 14;51(2):237-244. Epub 2019 Jan 14.

Department of Psychology, University of Minnesota Twin Cities, Minneapolis, MN, USA.

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http://www.nature.com/articles/s41588-018-0307-5
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http://dx.doi.org/10.1038/s41588-018-0307-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358542PMC
February 2019

Common Mitochondrial Haplogroups and Cutaneous Squamous Cell Carcinoma Risk.

Cancer Epidemiol Biomarkers Prev 2018 07 25;27(7):838-841. Epub 2018 Apr 25.

Department of Dermatology, Massachusetts General Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1158/1055-9965.EPI-18-0236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241517PMC
July 2018

Cytochrome P450 and matrix metalloproteinase genetic modifiers of disease severity in Cerebral Cavernous Malformation type 1.

Free Radic Biol Med 2016 Mar 19;92:100-109. Epub 2016 Jan 19.

Department of Clinical and Biological Sciences, University of Torino, Orbassano, TO, Italy; CCM Italia Research Network (www.ccmitalia.unito.it). Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2016.01.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774945PMC
March 2016

Polymorphisms in inflammatory and immune response genes associated with cerebral cavernous malformation type 1 severity.

Cerebrovasc Dis 2014 3;38(6):433-40. Epub 2014 Dec 3.

Center for Cerebrovascular Research, Department of Anesthesia and Perioperative Care, University of California, San Francisco, Calif., USA.

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https://www.karger.com/Article/FullText/369200
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http://dx.doi.org/10.1159/000369200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297571PMC
September 2015

Examination of rare missense variants in the CHRNA5-A3-B4 gene cluster to level of response to alcohol in the San Diego Sibling Pair study.

Alcohol Clin Exp Res 2013 Aug 4;37(8):1311-6. Epub 2013 Mar 4.

Department of Anesthesia and Perioperative Care, Center for Cerebrovascular Research, University of California, San Francisco, San Francisco, CA 94110, USA.

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http://doi.wiley.com/10.1111/acer.12099
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http://dx.doi.org/10.1111/acer.12099DOI Listing
August 2013

Contribution of common PCSK1 genetic variants to obesity in 8,359 subjects from multi-ethnic American population.

PLoS One 2013 25;8(2):e57857. Epub 2013 Feb 25.

Ernest Gallo Clinic and Research Center, Emeryville, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0057857PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581482PMC
January 2014

Genetics of Obesity: What have we Learned?

Curr Genomics 2011 May;12(3):169-79

Ernest Gallo Clinic and Research Center, Department of Neurology, University of California, San Francisco, Emeryville, California 94608, USA.

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http://www.eurekaselect.com/openurl/content.php?genre=articl
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http://dx.doi.org/10.2174/138920211795677895DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137002PMC
May 2011

Molecular basis of obesity: current status and future prospects.

Curr Genomics 2011 May;12(3):154-68

Ernest Gallo Clinic and Research Center, Department of Neurology, University of California, San Francisco, Emeryville, CA 94608, USA.

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http://dx.doi.org/10.2174/138920211795677921DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137001PMC
May 2011

Genetic and functional characterization of PCSK1.

Methods Mol Biol 2011 ;768:247-53

CNRS-8090-Institute of Biology, Pasteur Institute, Lille, France.

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http://dx.doi.org/10.1007/978-1-61779-204-5_13DOI Listing
March 2012

Genomic insights into early-onset obesity.

Genome Med 2010 Jun 23;2(6):36. Epub 2010 Jun 23.

CNRS UMR8199, Institute of Biology, Pasteur Institute, 1 Pr Calmette Street, 59000 Lille, France.

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http://dx.doi.org/10.1186/gm157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905096PMC
June 2010

Meta-analysis and functional effects of the SLC30A8 rs13266634 polymorphism on isolated human pancreatic islets.

Mol Genet Metab 2010 May 15;100(1):77-82. Epub 2010 Jan 15.

CNRS UMR 8090, Institute of Biology, Genomics and Molecular Physiology of Metabolic Diseases, Lille, France.

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http://linkinghub.elsevier.com/retrieve/pii/S109671921000002
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http://dx.doi.org/10.1016/j.ymgme.2010.01.001DOI Listing
May 2010