Helena Santos

Helena Santos

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Characterisation of ocular involvement in an experimental model of neuroschistosomiasis mansoni.

Mem Inst Oswaldo Cruz 2019 15;114:e190029. Epub 2019 Jul 15.

Universidade Federal de Minas Gerais, Faculdade de Medicina, Departamento de Doenças Infectoparasitárias, Belo Horizonte, MG, Brasil.

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http://dx.doi.org/10.1590/0074-02760190029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629375PMC
September 2019

Real-World Long-Term Effectiveness of Tumor Necrosis Factor Inhibitors in Psoriatic Arthritis Patients from the Rheumatic Diseases Portuguese Register.

J Rheumatol 2019 Aug 1. Epub 2019 Aug 1.

Serviço de Reumatologia e Doenças Ósseas Metabólicas, Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, Unidade de Investigação em Reumatologia, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Centro Académico de Medicina de Lisboa; Sociedade Portuguesa de Reumatologia; Serviço de Reumatologia, Centro Hospitalar de São João do Porto and Faculdade de Medicina da Universidade do Porto; Serviço de Reumatologia, Unidade Local de Saúde do Alto Minho; Instituto Português de Reumatologia; Serviço de Reumatologia, Centro Hospitalar e Universitário de Coimbra, Coimbra and Serviço de Reumatologia, Centro Hospitalar Universitário de Algarve, Faro, Portugal; Serviço de Reumatologia, Hospital Egas Moniz, Centro Hospitalar Lisboa Ocidental, Lisboa; Serviço de Reumatologia, Hospital Garcia de Orta; Serviço de Reumatologia, Centro Hospitalar do Baixo Vouga; Hospital CUF Descobertas. The Exchange study was financially supported by an unrestricted grant from Novartis Produtos Farmacêuticos SA. Novartis had no influence on the data collection, statistical analysis, manuscript preparation, or decision to submit. Address correspondence and reprint requests to: Elsa Vieira-Sousa, MD; Unidade de Investigação em Reumatologia, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Edifício Egas Moniz, Avenida Professor Egas Moniz, 1649-028 Lisboa;

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http://dx.doi.org/10.3899/jrheum.181272DOI Listing
August 2019

Mandibulofacial dysostosis with microcephaly: a syndrome to remember.

BMJ Case Rep 2019 Aug 13;12(8). Epub 2019 Aug 13.

Infancy and Adolescent Neurosciences Unit, Paediatrics Department, Centro Hospitalar de Vila Nova de Gaia/Espinho EPE, Vila Nova de Gaia, Portugal.

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http://dx.doi.org/10.1136/bcr-2019-229831DOI Listing
August 2019

Targeted next generation sequencing identifies novel pathogenic variants and provides molecular diagnoses in a cohort of pediatric and adult patients with unexplained mitochondrial dysfunction.

Mitochondrion 2019 Jul 1;47:309-317. Epub 2019 Mar 1.

Research & Development Unit, Human Genetics Department, National Institute of Health Doutor Ricardo Jorge, Porto, Portugal; Newborn Screening, Metabolism & Genetics Unit, Human Genetics Department, National Institute of Health Doutor Ricardo Jorge, Porto, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.mito.2019.02.006DOI Listing
July 2019

Development of a Measurement Tool to Assess Students' Knowledge and Perceptions About Cancer (SKPaC).

J Cancer Educ 2019 Jun;34(3):556-561

i3S - Institute for Research and Innovation in Health, University of Porto, Rua Alfredo Allen, 208, 4200-135, Porto, Portugal.

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http://dx.doi.org/10.1007/s13187-018-1341-9DOI Listing
June 2019

Combined transcriptomics-metabolomics profiling of the heat shock response in the hyperthermophilic archaeon Pyrococcus furiosus.

Extremophiles 2019 Jan 14;23(1):101-118. Epub 2018 Nov 14.

Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Av. da República, 2780-127, Oeiras, Portugal.

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http://link.springer.com/10.1007/s00792-018-1065-0
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http://dx.doi.org/10.1007/s00792-018-1065-0DOI Listing
January 2019

Production of mannosylglycerate in Saccharomyces cerevisiae by metabolic engineering and bioprocess optimization.

Microb Cell Fact 2018 Nov 16;17(1):178. Epub 2018 Nov 16.

Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa (ITQB NOVA), Oeiras, Portugal.

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https://microbialcellfactories.biomedcentral.com/articles/10
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http://dx.doi.org/10.1186/s12934-018-1023-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240254PMC
November 2018

Modification of a Putative Third Sodium Site in the Glycine Transporter GlyT2 Influences the Chloride Dependence of Substrate Transport.

Front Mol Neurosci 2018 24;11:347. Epub 2018 Sep 24.

Centro de Biología Molecular, "Severo Ochoa" Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid, Madrid, Spain.

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http://dx.doi.org/10.3389/fnmol.2018.00347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166138PMC
September 2018

Psychosocial impact of Parkinson's disease-associated dysarthria: Cross-cultural adaptation and validation of the Dysarthria Impact Profile into European Portuguese.

Geriatr Gerontol Int 2018 May 26;18(5):767-774. Epub 2018 Jan 26.

Clinical Pharmacological Unit, Instituto de Medicina Molecular, Faculty of Medicine, University of Lisbon, Lisbon, Portugal.

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http://dx.doi.org/10.1111/ggi.13255DOI Listing
May 2018

Classical fragile-X phenotype in a female infant disclosed by comprehensive genomic studies.

BMC Med Genet 2018 05 10;19(1):74. Epub 2018 May 10.

Unit for Multidisciplinary Research in Biomedicine, Abel Salazar Institute of Biomedical Sciences, University of Porto - UMIB-ICBAS-UP, Porto, Portugal.

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http://dx.doi.org/10.1186/s12881-018-0589-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946481PMC
May 2018

[Clinical and Epidemiological Study of Complicated Infection by Varicella-Zoster Virus in the Pediatric Age].

Acta Med Port 2015 Nov-Dec;28(6):741-8. Epub 2015 Dec 31.

Serviço de Pediatria Médica. Centro Hospitalar Vila Nova de Gaia/Espinho. Gaia. Portugal.

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March 2018

Trehalose, a temperature- and salt-induced solute with implications in pathobiology of Acinetobacter baumannii.

Environ Microbiol 2017 Dec 4;19(12):5088-5099. Epub 2017 Dec 4.

Department of Molecular Microbiology & Bioenergetics, Institute of Molecular Biosciences, Goethe-University Frankfurt am Main, Germany.

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http://dx.doi.org/10.1111/1462-2920.13987DOI Listing
December 2017

Experimental evidence for heritable reproductive time in 2 allochronic populations of pine processionary moth.

Insect Sci 2017 Apr 18;24(2):325-335. Epub 2016 Feb 18.

INRA Centre de Montpellier, UMR CBGP, F-34988, Montferrier-sur-Lez cedex, France.

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http://dx.doi.org/10.1111/1744-7917.12287DOI Listing
April 2017

Frenchay dysarthria assessment (FDA-2) in Parkinson's disease: cross-cultural adaptation and psychometric properties of the European Portuguese version.

J Neurol 2017 Jan 17;264(1):21-31. Epub 2016 Oct 17.

Clinical Pharmacological Unit, Instituto de Medicina Molecular, Faculty of Medicine, University of Lisbon, Lisbon, Portugal.

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http://dx.doi.org/10.1007/s00415-016-8298-6DOI Listing
January 2017

Glycerol Phosphate Cytidylyltransferase Stereospecificity Is Key to Understanding the Distinct Stereochemical Compositions of Glycerophosphoinositol in Bacteria and Archaea.

Appl Environ Microbiol 2017 01 15;83(1). Epub 2016 Dec 15.

Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Oeiras, Portugal

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http://dx.doi.org/10.1128/AEM.02462-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5165115PMC
January 2017

Stereospecificity of Corynebacterium glutamicum 2,3-butanediol dehydrogenase and implications for the stereochemical purity of bioproduced 2,3-butanediol.

Appl Microbiol Biotechnol 2016 Dec 29;100(24):10573-10583. Epub 2016 Sep 29.

Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Av. da República, EAN, 2780-157, Oeiras, Portugal.

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http://dx.doi.org/10.1007/s00253-016-7860-6DOI Listing
December 2016

The Nuanced Interplay of Intrinsic Disorder and Other Structural Properties Driving Protein Evolution.

Mol Biol Evol 2016 09 5;33(9):2248-56. Epub 2016 May 5.

Department of Biological Sciences, Biomolecular Sciences Institute, Florida International University

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http://dx.doi.org/10.1093/molbev/msw092DOI Listing
September 2016

Paralog-Specific Patterns of Structural Disorder and Phosphorylation in the Vertebrate SH3-SH2-Tyrosine Kinase Protein Family.

Genome Biol Evol 2016 09 19;8(9):2806-25. Epub 2016 Sep 19.

Department of Biological Sciences, Biomolecular Sciences Institute, Florida International University

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http://dx.doi.org/10.1093/gbe/evw194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630953PMC
September 2016

Functional Diversification after Gene Duplication: Paralog Specific Regions of Structural Disorder and Phosphorylation in p53, p63, and p73.

PLoS One 2016 22;11(3):e0151961. Epub 2016 Mar 22.

Department of Biological Sciences, Biomolecular Sciences Institute, Florida International University, Miami, Florida, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0151961PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803236PMC
August 2016

Potential applications of stress solutes from extremophiles in protein folding diseases and healthcare.

Extremophiles 2016 May 12;20(3):251-9. Epub 2016 Apr 12.

Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Av. da República-EAN, 2780-157, Oeiras, Portugal.

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http://link.springer.com/10.1007/s00792-016-0828-8
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http://dx.doi.org/10.1007/s00792-016-0828-8DOI Listing
May 2016

Earliest events in α-synuclein fibrillation probed with the fluorescence of intrinsic tyrosines.

J Photochem Photobiol B 2016 Jan 11;154:16-23. Epub 2015 Nov 11.

Centro de Química Estrutural, Instituto Superior Técnico, UTL, Lisboa, Portugal.

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http://dx.doi.org/10.1016/j.jphotobiol.2015.11.006DOI Listing
January 2016

Validation of Portuguese-translated computer touch-screen questionnaires in patients with rheumatoid arthritis and spondyloarthritis, compared with paper formats.

Rheumatol Int 2015 Dec 7;35(12):2029-35. Epub 2015 Sep 7.

Eurotrials Scientific Consultants, Rua Tierno Galvan, Torre 3, Piso 16, 1070-274, Lisbon, Portugal.

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http://dx.doi.org/10.1007/s00296-015-3347-5DOI Listing
December 2015

[Educational strategies to improve adherence to patient identification].

Rev Gaucha Enferm 2015 Dec;36(4):43-8

Escola de Enfermagem, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brasil.

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http://dx.doi.org/10.1590/1983-1447.2015.04.54289DOI Listing
December 2015

Molecular Identification of Food Sources in Triatomines in the Brazilian Northeast: Roles of Goats and Rodents in Chagas Disease Epidemiology.

Am J Trop Med Hyg 2015 Nov 8;93(5):994-7. Epub 2015 Sep 8.

Laboratório de Ecoepidemiologia da doença de Chagas, IOC/Fiocruz, Rio de Janeiro, Brazil; Laboratório de Estudos Integrados em Protozoologia, IOC/Fiocruz, Rio de Janeiro, Brazil; UMR EGCE (Evolution, Genome, Comportment, Ecologie) Univ-Paris-Sud-CNRS-IRD, IDEEV, Univ-Paris-Saclay, Gif-sur-Yvette Cedex, France; Université Paris Sud, Orsay, France; Laboratório Ecologia Animal, Programa de Pós-Graduação em Ecologia e Monitoramento Ambiental-PPGEMA, Universidade Federal da Paraíba-UFPB, Campus IV, Rio Tinto, PB, Paraíba, Brazil; Departamento de Ciências Biológicas, Faculdade de Ciências Farmacêuticas (UNESP), Araraquara, São Paulo, Brazil.

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http://dx.doi.org/10.4269/ajtmh.15-0156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703289PMC
November 2015

"Cancer--Educate to Prevent"--high-school teachers, the new promoters of cancer prevention education campaigns.

PLoS One 2014 9;9(5):e96672. Epub 2014 May 9.

Public Awareness of Cancer Unit, Cancer Institute of Pathology and Molecular Immunology of University of Porto - Ipatimup, Porto, Portugal; Department of Pathology and Oncology, Faculty of Medicine of the University of Porto - FMUP, Porto, Portugal.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0096672PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016009PMC
October 2015

Engineering Corynebacterium glutamicum for the production of 2,3-butanediol.

Microb Cell Fact 2015 Oct 29;14:171. Epub 2015 Oct 29.

Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Av. da República-EAN, 2780-157, Oeiras, Portugal.

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http://dx.doi.org/10.1186/s12934-015-0362-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625470PMC
October 2015

Growth hormone deficiency in a patient with mitochondrial disease.

J Pediatr Endocrinol Metab 2015 Sep;28(9-10):1003-4

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http://dx.doi.org/10.1515/jpem-2014-0315DOI Listing
September 2015

Purification and crystallographic studies of a putative carbohydrate-binding module from the Ruminococcus flavefaciens FD-1 endoglucanase Cel5A.

Acta Crystallogr F Struct Biol Commun 2015 Aug 28;71(Pt 8):958-61. Epub 2015 Jul 28.

CIISA, Faculdade de Medicina Veterinari, Universidade de Lisboa, Avenida da Universidade Técnica, 1300-477 Lisbon, Portugal.

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http://dx.doi.org/10.1107/S2053230X15009784DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528923PMC
August 2015

A novel pathway for the synthesis of inositol phospholipids uses cytidine diphosphate (CDP)-inositol as donor of the polar head group.

Environ Microbiol 2015 Jul 11;17(7):2492-504. Epub 2015 Feb 11.

Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Av. da República-EAN, Apartado 127, Oeiras, 2780-157, Portugal.

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http://dx.doi.org/10.1111/1462-2920.12734DOI Listing
July 2015

Mannitol-1-phosphate dehydrogenases/phosphatases: a family of novel bifunctional enzymes for bacterial adaptation to osmotic stress.

Environ Microbiol 2015 Mar 4;17(3):711-9. Epub 2014 Jun 4.

Molecular Microbiology & Bioenergetics, Institute of Molecular Biosciences, Johann Wolfgang Goethe University Frankfurt am Main, Frankfurt, Germany.

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http://dx.doi.org/10.1111/1462-2920.12503DOI Listing
March 2015

A unique glyceryl diglycoside identified in the thermophilic, radiation-resistant bacterium Rubrobacter xylanophilus.

Extremophiles 2015 Mar 3;19(2):373-82. Epub 2015 Jan 3.

Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Av. da República-EAN, Apartado 127, 2780-157, Oeiras, Portugal,

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http://dx.doi.org/10.1007/s00792-014-0723-0DOI Listing
March 2015

DAS28, CDAI and SDAI cut-offs do not translate the same information: results from the Rheumatic Diseases Portuguese Register Reuma.pt.

Rheumatology (Oxford) 2015 Feb 29;54(2):286-91. Epub 2014 Aug 29.

Portuguese Society of Rheumatology, Lisbon, Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Clínica Universitária de Reumatologia, Centro Hospitalar e Faculdade de Medicina da Universidade de Coimbra, Rheumatology Department, Garcia de Orta Hospital, Almada, Rheumatology Department, CHLN-Santa Maria Hospital, CAML, Lisbon, Rheumatology Department, Centro Hospitalar e Universitário de Coimbra, Portuguese Institute of Rheumatology, Lisbon, Rheumatology Department, ULSAM, EPE - Unidade Local de Saúde do Alto Minho, Ponte de Lima, CEDOC-Faculdade de Ciências Médicas da Universidade Nova de Lisboa, Rheumatology Department, CHLO-Egas Moniz Hospital, Lisbon, Rheumatology Department, CHBV-Infante D. Pedro Hospital, Aveiro, Rheumatology Department, Divino Espírito Santo Hospital, Ponta Delgada, Faculdade de Ciências Médicas da Universidade Nova de Lisboa, Lisbon, Rheumatology Department, São João University Hospital, Porto and Clínica Reumatológica Dr Melo Gomes, Lisbon, Portugal. Portuguese Society of Rheumatology, Lisbon, Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Clínica Universitária de Reumatologia, Centro Hospitalar e Faculdade de Medicina da Universidade de Coimbra, Rheumatology Department, Garcia de Orta Hospital, Almada, Rheumatology Department, CHLN-Santa Maria Hospital, CAML, Lisbon, Rheumatology Department, Centro Hospitalar e Universitário de Coimbra, Portuguese Institute of Rheumatology, Lisbon, Rheumatology Department, ULSAM, EPE - Unidade Local de Saúde do Alto Minho, Ponte de Lima, CEDOC-Faculdade de Ciências Médicas da Universidade Nova de Lisboa, Rheumatology Department, CHLO-Egas Moniz Hospital, Lisbon, Rheumatology Department, CHBV-Infante D. Pedro Hospital, Aveiro, Rheumatology Department, Divino Espírito Santo Hospital, Ponta Delgada, Faculdade de Ciências Médicas da Universidade Nova de

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http://dx.doi.org/10.1093/rheumatology/keu313DOI Listing
February 2015

Crystallization and preliminary X-ray diffraction analysis of a trimodular endo-β-1,4-glucanase (Cel5B) from Bacillus halodurans.

Acta Crystallogr F Struct Biol Commun 2014 Dec 14;70(Pt 12):1628-30. Epub 2014 Nov 14.

CIISA, Faculdade de Medicina Veterinaria, Universidade de Lisboa, Avenida da Universidade Técnica, 1300-477 Lisbon, Portugal.

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http://dx.doi.org/10.1107/S2053230X1402319XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259227PMC
December 2014

Visual diagnosis: 8-day-old hypotonic newborn with sparse hair.

Pediatr Rev 2014 Nov;35(11):e53-6

Serviço Pediatria, Centro Hospitalar Vila Nova de Gaia, Portugal.

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http://dx.doi.org/10.1542/pir.35-11-e53DOI Listing
November 2014

Mannosylglycerate: structural analysis of biosynthesis and evolutionary history.

Extremophiles 2014 Sep 10;18(5):835-52. Epub 2014 Aug 10.

Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Avenida da República-EAN, 2780-157, Oeiras, Portugal.

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http://dx.doi.org/10.1007/s00792-014-0661-xDOI Listing
September 2014

International conference on extremophiles 2014.

Extremophiles 2014 Sep;18(5):789-90

Institute of Technical Microbiology, Hamburg University of Technology (TUHH), Kasernenstr. 12, 21073, Hamburg, Germany,

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http://dx.doi.org/10.1007/s00792-014-0690-5DOI Listing
September 2014

Mannosylglycerate and di-myo-inositol phosphate have interchangeable roles during adaptation of Pyrococcus furiosus to heat stress.

Appl Environ Microbiol 2014 Jul 2;80(14):4226-33. Epub 2014 May 2.

Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal.

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http://dx.doi.org/10.1128/AEM.00559-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068688PMC
July 2014

Construction of GH16 β-glucanase mini-cellulosomes to improve the nutritive value of barley-based diets for broilers.

J Agric Food Chem 2014 Jul 16;62(30):7496-506. Epub 2014 Jul 16.

CIISA-Faculdade de Medicina Veterinária, Universidade de Lisboa , Avenida da Universidade Técnica, 1300-477 Lisboa, Portugal.

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http://dx.doi.org/10.1021/jf502157yDOI Listing
July 2014

Overproduction, purification, crystallization and preliminary X-ray characterization of the family 46 carbohydrate-binding module (CBM46) of endo-β-1,4-glucanase B (CelB) from Bacillus halodurans.

Acta Crystallogr F Struct Biol Commun 2014 Jun 10;70(Pt 6):754-7. Epub 2014 May 10.

CIISA-Faculdade de Medicina Veterinaria, Universidade de Lisboa, Avenida da Universidade Técnica, 1300-477 Lisbon, Portugal.

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http://dx.doi.org/10.1107/S2053230X14008395DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051530PMC
June 2014

X-ray structure of a CDP-alcohol phosphatidyltransferase membrane enzyme and insights into its catalytic mechanism.

Nat Commun 2014 Jun 19;5:4169. Epub 2014 Jun 19.

Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa (ITQB-UNL), Av. República, EAN, 2780-157 Oeiras, Portugal.

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http://dx.doi.org/10.1038/ncomms5169DOI Listing
June 2014

Blastocystis sp. in splenic cysts: causative agent or accidental association? A unique case report.

Parasit Vectors 2014 Apr 29;7:207. Epub 2014 Apr 29.

Laboratório de Avaliação e Promoção da Saúde Ambiental, Instituto Oswaldo Cruz/FIOCRUZ, Av, Brasil, 4365-Pavilhão Lauro Travassos, Manguinhos, Rio de Janeiro, RJ 21,045-900, Brazil.

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http://dx.doi.org/10.1186/1756-3305-7-207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026114PMC
April 2014

Glutamine synthetase 2 is not essential for biosynthesis of compatible solutes in Halobacillus halophilus.

Front Microbiol 2014 14;5:168. Epub 2014 Apr 14.

Molecular Microbiology and Bioenergetics, Institute of Molecular Biosciences, Johann Wolfgang Goethe-University of Frankfurt am Main Frankfurt am Main, Germany.

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http://dx.doi.org/10.3389/fmicb.2014.00168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995056PMC
April 2014

Finding Rheumatoid Arthritis Impact on Life (FRAIL Study): economic burden.

Acta Reumatol Port 2012 Apr-Jun;37(2):134-42

Instituto Português de Reumatologia, Lisboa, Portugal.

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March 2014

Protein evolution along phylogenetic histories under structurally constrained substitution models.

Bioinformatics 2013 Dec 12;29(23):3020-8. Epub 2013 Sep 12.

Centre for Molecular Biology 'Severo Ochoa', Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain and Department of Biochemistry, Genetics and Immunology, University of Vigo, Vigo, Spain.

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http://dx.doi.org/10.1093/bioinformatics/btt530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221705PMC
December 2013

Phenotypic divergence in reproductive traits of a moth population experiencing a phenological shift.

Ecol Evol 2013 Dec 20;3(15):5098-108. Epub 2013 Nov 20.

Centro de Estudos Florestais, Instituto Superior de Agronomia, Universidade de Lisboa Tapada da Ajuda, 1349-017, Lisboa, Portugal.

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http://dx.doi.org/10.1002/ece3.865DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892371PMC
December 2013

From physiology to systems metabolic engineering for the production of biochemicals by lactic acid bacteria.

Biotechnol Adv 2013 Nov 6;31(6):764-88. Epub 2013 Apr 6.

Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal.

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http://dx.doi.org/10.1016/j.biotechadv.2013.03.011DOI Listing
November 2013

High-resolution structure of an atypical α-phosphoglucomutase related to eukaryotic phosphomannomutases.

Acta Crystallogr D Biol Crystallogr 2013 Oct 20;69(Pt 10):2008-16. Epub 2013 Sep 20.

Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa (ITQB-UNL), 2780-157 Oeiras, Portugal.

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http://scripts.iucr.org/cgi-bin/paper?S0907444913017046
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http://dx.doi.org/10.1107/S0907444913017046DOI Listing
October 2013

Novel HLA-B27-restricted epitopes from Chlamydia trachomatis generated upon endogenous processing of bacterial proteins suggest a role of molecular mimicry in reactive arthritis.

J Biol Chem 2013 Sep 18;288(36):25810-25. Epub 2013 Jul 18.

Centro de Biología Molecular Severo Ochoa, Consejo Superior de Investigaciones Científicas and Universidad Autónoma, Madrid, Spain.

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http://dx.doi.org/10.1074/jbc.M113.493247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764788PMC
September 2013

Mannitol, a compatible solute synthesized by Acinetobacter baylyi in a two-step pathway including a salt-induced and salt-dependent mannitol-1-phosphate dehydrogenase.

Environ Microbiol 2013 Aug 17;15(8):2187-97. Epub 2013 Feb 17.

Molecular Microbiology & Bioenergetics, Institute of Molecular Biosciences, Goethe University Frankfurt, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1111/1462-2920.12090DOI Listing
August 2013

Inhibition of formation of α-synuclein inclusions by mannosylglycerate in a yeast model of Parkinson's disease.

Biochim Biophys Acta 2013 Aug 19;1830(8):4065-72. Epub 2013 Apr 19.

Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal.

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http://dx.doi.org/10.1016/j.bbagen.2013.04.015DOI Listing
August 2013

Newborn screening for medium-chain acyl-CoA dehydrogenase deficiency: regional experience and high incidence of carnitine deficiency.

Orphanet J Rare Dis 2013 Jul 10;8:102. Epub 2013 Jul 10.

Unidad de Diagnóstico y Tratamiento de Enfermedades Congénitas del Metabolismo, Departamento de Pediatría, Hospital Clínico Universitario, Universidad de Santiago, Santiago de Compostela, Spain.

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http://dx.doi.org/10.1186/1750-1172-8-102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718718PMC
July 2013

The fate of acetic acid during glucose co-metabolism by the spoilage yeast Zygosaccharomyces bailii.

PLoS One 2012 28;7(12):e52402. Epub 2012 Dec 28.

Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0052402PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532111PMC
June 2013

Experimental amoebic liver abscess in hamsters caused by trophozoites of a Brazilian strain of Entamoeba dispar.

Exp Parasitol 2013 May 1;134(1):39-47. Epub 2013 Feb 1.

Department of Pathology, Fluminense Federal University, Niteroi, RJ, Brazil.

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http://dx.doi.org/10.1016/j.exppara.2013.01.015DOI Listing
May 2013

Characterizing conformation changes in proteins through the torsional elastic response.

Biochim Biophys Acta 2013 May 19;1834(5):836-46. Epub 2013 Feb 19.

Centro de Biologia Molecular Severo Ochoa, CSIC-UAM, Madrid, Spain.

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http://dx.doi.org/10.1016/j.bbapap.2013.02.010DOI Listing
May 2013

Trichorhinophalangeal Syndrome Type I: A Patient with Two Novel and Different Mutations in the TRPS1 Gene.

Case Rep Genet 2013 17;2013:748057. Epub 2013 Apr 17.

Paediatrics Department, Centro Hospitalar de Vila Nova de Gaia/Espinho, EPE, Unidade II, 4400-129 Vila Nova de Gaia, Portugal.

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http://dx.doi.org/10.1155/2013/748057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652099PMC
May 2013

Organic solutes in the deepest phylogenetic branches of the Bacteria: identification of α(1-6)glucosyl-α(1-2)glucosylglycerate in Persephonella marina.

Extremophiles 2013 Jan 24;17(1):137-46. Epub 2012 Nov 24.

Biology Division, Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Av. da República, Estação Agronómica Nacional, 2780-157, Oeiras, Portugal.

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http://dx.doi.org/10.1007/s00792-012-0500-xDOI Listing
January 2013

Production and crystallization of α-phosphoglucomutase from Lactococcus lactis.

Acta Crystallogr Sect F Struct Biol Cryst Commun 2012 Sep 31;68(Pt 9):1113-5. Epub 2012 Aug 31.

Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa (ITQB-UNL), Avenida da República, 2780-157 Oeiras, Portugal.

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http://dx.doi.org/10.1107/S1744309112032629DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433211PMC
September 2012

MM-ISMSA: An Ultrafast and Accurate Scoring Function for Protein-Protein Docking.

J Chem Theory Comput 2012 Sep 14;8(9):3395-408. Epub 2012 Aug 14.

Unidad de Bioinformática, Centro de Biología Molecular Severo Ochoa (CSIC-UAM), Campus de Cantoblanco UAM, E-28049 Madrid, Spain.

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http://dx.doi.org/10.1021/ct300497zDOI Listing
September 2012

Mannosylglycerate stabilizes staphylococcal nuclease with restriction of slow β-sheet motions.

Protein Sci 2012 Aug 15;21(8):1126-37. Epub 2012 Jun 15.

Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal.

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http://doi.wiley.com/10.1002/pro.2100
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http://dx.doi.org/10.1002/pro.2100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537234PMC
August 2012

CRDOCK: an ultrafast multipurpose protein-ligand docking tool.

J Chem Inf Model 2012 Aug 19;52(8):2300-9. Epub 2012 Jul 19.

Departamento de Farmacología, Universidad de Alcalá, E-28871 Alcalá de Henares, Madrid, Spain.

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http://dx.doi.org/10.1021/ci300194aDOI Listing
August 2012

Evolution of the biosynthesis of di-myo-inositol phosphate, a marker of adaptation to hot marine environments.

Environ Microbiol 2012 Mar 26;14(3):691-701. Epub 2011 Oct 26.

Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Av. da República-EAN, Apartado 127, 2780-157 Oeiras, Portugal.

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http://dx.doi.org/10.1111/j.1462-2920.2011.02621.xDOI Listing
March 2012

ANKH and susceptibility to and severity of ankylosing spondylitis.

J Rheumatol 2012 Jan 15;39(1):131-4. Epub 2011 Nov 15.

Faculdade de Ciências Médicas, Universidade Nova de Lisboa, CEDOC, Campo Mártires da Pátria 130, Lisbon 1169-056, Portugal.

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http://dx.doi.org/10.3899/jrheum.110681DOI Listing
January 2012

Three-dimensional structure of mannosyl-3-phosphoglycerate phosphatase from Thermus thermophilus HB27: a new member of the haloalcanoic acid dehalogenase superfamily.

Biochemistry 2011 Nov 13;50(44):9551-67. Epub 2011 Oct 13.

ITQB-Instituto de Tecnologia Quı́mica e Biológica, Universidade Nova de Lisboa, Apartado 127, 2781-901 Oeiras, Portugal.

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http://dx.doi.org/10.1021/bi201171hDOI Listing
November 2011

Salt adaptation in Acinetobacter baylyi: identification and characterization of a secondary glycine betaine transporter.

Arch Microbiol 2011 Oct 13;193(10):723-30. Epub 2011 May 13.

Molecular Microbiology and Bioenergetics, Institute of Molecular Biosciences, Johann Wolfgang Goethe University Frankfurt, Max-von-Laue-Str. 9, 60438, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1007/s00203-011-0713-xDOI Listing
October 2011

High yields of 2,3-butanediol and mannitol in Lactococcus lactis through engineering of NAD⁺ cofactor recycling.

Appl Environ Microbiol 2011 Oct 12;77(19):6826-35. Epub 2011 Aug 12.

Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Av. República (EAN), 2780-157 Oeiras, Portugal.

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http://dx.doi.org/10.1128/AEM.05544-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187077PMC
October 2011