Helena Kuivaniemi

Helena Kuivaniemi

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Helena Kuivaniemi

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Type III collagen (COL3A1): Gene and protein structure, tissue distribution, and associated diseases.

Gene 2019 Jul 7;707:151-171. Epub 2019 May 7.

Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Stellenbosch University, Cape Town, South Africa; Bioinformatics Unit, South African Tuberculosis Bioinformatics Initiative, Stellenbosch University, Cape Town, South Africa; DST-NRF Centre of Excellence for Biomedical Tuberculosis Research, Stellenbosch University, Cape Town, South Africa; South African Medical Research Council Centre for Tuberculosis Research, Stellenbosch University, Cape Town, South Africa; Centre for Bioinformatics and Computational Biology, Stellenbosch University, Stellenbosch, South Africa.

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http://dx.doi.org/10.1016/j.gene.2019.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579750PMC
July 2019

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

Authors:
Valérie Turcot Yingchang Lu Heather M Highland Claudia Schurmann Anne E Justice Rebecca S Fine Jonathan P Bradfield Tõnu Esko Ayush Giri Mariaelisa Graff Xiuqing Guo Audrey E Hendricks Tugce Karaderi Adelheid Lempradl Adam E Locke Anubha Mahajan Eirini Marouli Suthesh Sivapalaratnam Kristin L Young Tamuno Alfred Mary F Feitosa Nicholas G D Masca Alisa K Manning Carolina Medina-Gomez Poorva Mudgal Maggie C Y Ng Alex P Reiner Sailaja Vedantam Sara M Willems Thomas W Winkler Gonçalo Abecasis Katja K Aben Dewan S Alam Sameer E Alharthi Matthew Allison Philippe Amouyel Folkert W Asselbergs Paul L Auer Beverley Balkau Lia E Bang Inês Barroso Lisa Bastarache Marianne Benn Sven Bergmann Lawrence F Bielak Matthias Blüher Michael Boehnke Heiner Boeing Eric Boerwinkle Carsten A Böger Jette Bork-Jensen Michiel L Bots Erwin P Bottinger Donald W Bowden Ivan Brandslund Gerome Breen Murray H Brilliant Linda Broer Marco Brumat Amber A Burt Adam S Butterworth Peter T Campbell Stefania Cappellani David J Carey Eulalia Catamo Mark J Caulfield John C Chambers Daniel I Chasman Yii-Der I Chen Rajiv Chowdhury Cramer Christensen Audrey Y Chu Massimiliano Cocca Francis S Collins James P Cook Janie Corley Jordi Corominas Galbany Amanda J Cox David S Crosslin Gabriel Cuellar-Partida Angela D'Eustacchio John Danesh Gail Davies Paul I W Bakker Mark C H Groot Renée Mutsert Ian J Deary George Dedoussis Ellen W Demerath Martin Heijer Anneke I Hollander Hester M Ruijter Joe G Dennis Josh C Denny Emanuele Di Angelantonio Fotios Drenos Mengmeng Du Marie-Pierre Dubé Alison M Dunning Douglas F Easton Todd L Edwards David Ellinghaus Patrick T Ellinor Paul Elliott Evangelos Evangelou Aliki-Eleni Farmaki I Sadaf Farooqi Jessica D Faul Sascha Fauser Shuang Feng Ele Ferrannini Jean Ferrieres Jose C Florez Ian Ford Myriam Fornage Oscar H Franco Andre Franke Paul W Franks Nele Friedrich Ruth Frikke-Schmidt Tessel E Galesloot Wei Gan Ilaria Gandin Paolo Gasparini Jane Gibson Vilmantas Giedraitis Anette P Gjesing Penny Gordon-Larsen Mathias Gorski Hans-Jörgen Grabe Struan F A Grant Niels Grarup Helen L Griffiths Megan L Grove Vilmundur Gudnason Stefan Gustafsson Jeff Haessler Hakon Hakonarson Anke R Hammerschlag Torben Hansen Kathleen Mullan Harris Tamara B Harris Andrew T Hattersley Christian T Have Caroline Hayward Liang He Nancy L Heard-Costa Andrew C Heath Iris M Heid Øyvind Helgeland Jussi Hernesniemi Alex W Hewitt Oddgeir L Holmen G Kees Hovingh Joanna M M Howson Yao Hu Paul L Huang Jennifer E Huffman M Arfan Ikram Erik Ingelsson Anne U Jackson Jan-Håkan Jansson Gail P Jarvik Gorm B Jensen Yucheng Jia Stefan Johansson Marit E Jørgensen Torben Jørgensen J Wouter Jukema Bratati Kahali René S Kahn Mika Kähönen Pia R Kamstrup Stavroula Kanoni Jaakko Kaprio Maria Karaleftheri Sharon L R Kardia Fredrik Karpe Sekar Kathiresan Frank Kee Lambertus A Kiemeney Eric Kim Hidetoshi Kitajima Pirjo Komulainen Jaspal S Kooner Charles Kooperberg Tellervo Korhonen Peter Kovacs Helena Kuivaniemi Zoltán Kutalik Kari Kuulasmaa Johanna Kuusisto Markku Laakso Timo A Lakka David Lamparter Ethan M Lange Leslie A Lange Claudia Langenberg Eric B Larson Nanette R Lee Terho Lehtimäki Cora E Lewis Huaixing Li Jin Li Ruifang Li-Gao Honghuang Lin Keng-Hung Lin Li-An Lin Xu Lin Lars Lind Jaana Lindström Allan Linneberg Ching-Ti Liu Dajiang J Liu Yongmei Liu Ken S Lo Artitaya Lophatananon Andrew J Lotery Anu Loukola Jian'an Luan Steven A Lubitz Leo-Pekka Lyytikäinen Satu Männistö Gaëlle Marenne Angela L Mazul Mark I McCarthy Roberta McKean-Cowdin Sarah E Medland Karina Meidtner Lili Milani Vanisha Mistry Paul Mitchell Karen L Mohlke Leena Moilanen Marie Moitry Grant W Montgomery Dennis O Mook-Kanamori Carmel Moore Trevor A Mori Andrew D Morris Andrew P Morris Martina Müller-Nurasyid Patricia B Munroe Mike A Nalls Narisu Narisu Christopher P Nelson Matt Neville Sune F Nielsen Kjell Nikus Pål R Njølstad Børge G Nordestgaard Dale R Nyholt Jeffrey R O'Connel Michelle L O'Donoghue Loes M Olde Loohuis Roel A Ophoff Katharine R Owen Chris J Packard Sandosh Padmanabhan Colin N A Palmer Nicholette D Palmer Gerard Pasterkamp Aniruddh P Patel Alison Pattie Oluf Pedersen Peggy L Peissig Gina M Peloso Craig E Pennell Markus Perola James A Perry John R B Perry Tune H Pers Thomas N Person Annette Peters Eva R B Petersen Patricia A Peyser Ailith Pirie Ozren Polasek Tinca J Polderman Hannu Puolijoki Olli T Raitakari Asif Rasheed Rainer Rauramaa Dermot F Reilly Frida Renström Myriam Rheinberger Paul M Ridker John D Rioux Manuel A Rivas David J Roberts Neil R Robertson Antonietta Robino Olov Rolandsson Igor Rudan Katherine S Ruth Danish Saleheen Veikko Salomaa Nilesh J Samani Yadav Sapkota Naveed Sattar Robert E Schoen Pamela J Schreiner Matthias B Schulze Robert A Scott Marcelo P Segura-Lepe Svati H Shah Wayne H-H Sheu Xueling Sim Andrew J Slater Kerrin S Small Albert V Smith Lorraine Southam Timothy D Spector Elizabeth K Speliotes John M Starr Kari Stefansson Valgerdur Steinthorsdottir Kathleen E Stirrups Konstantin Strauch Heather M Stringham Michael Stumvoll Liang Sun Praveen Surendran Amy J Swift Hayato Tada Katherine E Tansey Jean-Claude Tardif Kent D Taylor Alexander Teumer Deborah J Thompson Gudmar Thorleifsson Unnur Thorsteinsdottir Betina H Thuesen Anke Tönjes Gerard Tromp Stella Trompet Emmanouil Tsafantakis Jaakko Tuomilehto Anne Tybjaerg-Hansen Jonathan P Tyrer Rudolf Uher André G Uitterlinden Matti Uusitupa Sander W Laan Cornelia M Duijn Nienke Leeuwen Jessica van Setten Mauno Vanhala Anette Varbo Tibor V Varga Rohit Varma Digna R Velez Edwards Sita H Vermeulen Giovanni Veronesi Henrik Vestergaard Veronique Vitart Thomas F Vogt Uwe Völker Dragana Vuckovic Lynne E Wagenknecht Mark Walker Lars Wallentin Feijie Wang Carol A Wang Shuai Wang Yiqin Wang Erin B Ware Nicholas J Wareham Helen R Warren Dawn M Waterworth Jennifer Wessel Harvey D White Cristen J Willer James G Wilson Daniel R Witte Andrew R Wood Ying Wu Hanieh Yaghootkar Jie Yao Pang Yao Laura M Yerges-Armstrong Robin Young Eleftheria Zeggini Xiaowei Zhan Weihua Zhang Jing Hua Zhao Wei Zhao Wei Zhao Wei Zhou Krina T Zondervan Jerome I Rotter John A Pospisilik Fernando Rivadeneira Ingrid B Borecki Panos Deloukas Timothy M Frayling Guillaume Lettre Kari E North Cecilia M Lindgren Joel N Hirschhorn Ruth J F Loos

Nat Genet 2019 Jul;51(7):1191-1192

Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1038/s41588-019-0447-2DOI Listing
July 2019

Parkinson's disease in Nigeria: A review of published studies and recommendations for future research.

Parkinsonism Relat Disord 2019 May 8;62:36-43. Epub 2018 Dec 8.

Neurology Unit, Department of Medicine, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2018.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556138PMC
May 2019

Risk Factor Assessment in a Greek Cohort of Patients With Large Abdominal Aortic Aneurysms.

Angiology 2019 Jan 8;70(1):35-40. Epub 2018 May 8.

1 Department of Vascular Surgery, University Hospital of Larissa, Greece.

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http://dx.doi.org/10.1177/0003319718774474DOI Listing
January 2019

Abdominal aortic aneurysms.

Nat Rev Dis Primers 2018 10 18;4(1):34. Epub 2018 Oct 18.

Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1038/s41572-018-0030-7DOI Listing
October 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

Authors:
Valérie Turcot Yingchang Lu Heather M Highland Claudia Schurmann Anne E Justice Rebecca S Fine Jonathan P Bradfield Tõnu Esko Ayush Giri Mariaelisa Graff Xiuqing Guo Audrey E Hendricks Tugce Karaderi Adelheid Lempradl Adam E Locke Anubha Mahajan Eirini Marouli Suthesh Sivapalaratnam Kristin L Young Tamuno Alfred Mary F Feitosa Nicholas G D Masca Alisa K Manning Carolina Medina-Gomez Poorva Mudgal Maggie C Y Ng Alex P Reiner Sailaja Vedantam Sara M Willems Thomas W Winkler Gonçalo Abecasis Katja K Aben Dewan S Alam Sameer E Alharthi Matthew Allison Philippe Amouyel Folkert W Asselbergs Paul L Auer Beverley Balkau Lia E Bang Inês Barroso Lisa Bastarache Marianne Benn Sven Bergmann Lawrence F Bielak Matthias Blüher Michael Boehnke Heiner Boeing Eric Boerwinkle Carsten A Böger Jette Bork-Jensen Michiel L Bots Erwin P Bottinger Donald W Bowden Ivan Brandslund Gerome Breen Murray H Brilliant Linda Broer Marco Brumat Amber A Burt Adam S Butterworth Peter T Campbell Stefania Cappellani David J Carey Eulalia Catamo Mark J Caulfield John C Chambers Daniel I Chasman Yii-Der I Chen Rajiv Chowdhury Cramer Christensen Audrey Y Chu Massimiliano Cocca Francis S Collins James P Cook Janie Corley Jordi Corominas Galbany Amanda J Cox David S Crosslin Gabriel Cuellar-Partida Angela D'Eustacchio John Danesh Gail Davies Paul I W Bakker Mark C H Groot Renée Mutsert Ian J Deary George Dedoussis Ellen W Demerath Martin Heijer Anneke I Hollander Hester M Ruijter Joe G Dennis Josh C Denny Emanuele Angelantonio Fotios Drenos Mengmeng Du Marie-Pierre Dubé Alison M Dunning Douglas F Easton Todd L Edwards David Ellinghaus Patrick T Ellinor Paul Elliott Evangelos Evangelou Aliki-Eleni Farmaki I Sadaf Farooqi Jessica D Faul Sascha Fauser Shuang Feng Ele Ferrannini Jean Ferrieres Jose C Florez Ian Ford Myriam Fornage Oscar H Franco Andre Franke Paul W Franks Nele Friedrich Ruth Frikke-Schmidt Tessel E Galesloot Wei Gan Ilaria Gandin Paolo Gasparini Jane Gibson Vilmantas Giedraitis Anette P Gjesing Penny Gordon-Larsen Mathias Gorski Hans-Jörgen Grabe Struan F A Grant Niels Grarup Helen L Griffiths Megan L Grove Vilmundur Gudnason Stefan Gustafsson Jeff Haessler Hakon Hakonarson Anke R Hammerschlag Torben Hansen Kathleen Mullan Harris Tamara B Harris Andrew T Hattersley Christian T Have Caroline Hayward Liang He Nancy L Heard-Costa Andrew C Heath Iris M Heid Øyvind Helgeland Jussi Hernesniemi Alex W Hewitt Oddgeir L Holmen G Kees Hovingh Joanna M M Howson Yao Hu Paul L Huang Jennifer E Huffman M Arfan Ikram Erik Ingelsson Anne U Jackson Jan-Håkan Jansson Gail P Jarvik Gorm B Jensen Yucheng Jia Stefan Johansson Marit E Jørgensen Torben Jørgensen J Wouter Jukema Bratati Kahali René S Kahn Mika Kähönen Pia R Kamstrup Stavroula Kanoni Jaakko Kaprio Maria Karaleftheri Sharon L R Kardia Fredrik Karpe Sekar Kathiresan Frank Kee Lambertus A Kiemeney Eric Kim Hidetoshi Kitajima Pirjo Komulainen Jaspal S Kooner Charles Kooperberg Tellervo Korhonen Peter Kovacs Helena Kuivaniemi Zoltán Kutalik Kari Kuulasmaa Johanna Kuusisto Markku Laakso Timo A Lakka David Lamparter Ethan M Lange Leslie A Lange Claudia Langenberg Eric B Larson Nanette R Lee Terho Lehtimäki Cora E Lewis Huaixing Li Jin Li Ruifang Li-Gao Honghuang Lin Keng-Hung Lin Li-An Lin Xu Lin Lars Lind Jaana Lindström Allan Linneberg Ching-Ti Liu Dajiang J Liu Yongmei Liu Ken S Lo Artitaya Lophatananon Andrew J Lotery Anu Loukola Jian'an Luan Steven A Lubitz Leo-Pekka Lyytikäinen Satu Männistö Gaëlle Marenne Angela L Mazul Mark I McCarthy Roberta McKean-Cowdin Sarah E Medland Karina Meidtner Lili Milani Vanisha Mistry Paul Mitchell Karen L Mohlke Leena Moilanen Marie Moitry Grant W Montgomery Dennis O Mook-Kanamori Carmel Moore Trevor A Mori Andrew D Morris Andrew P Morris Martina Müller-Nurasyid Patricia B Munroe Mike A Nalls Narisu Narisu Christopher P Nelson Matt Neville Sune F Nielsen Kjell Nikus Pål R Njølstad Børge G Nordestgaard Dale R Nyholt Jeffrey R O'Connel Michelle L O'Donoghue Loes M Olde Loohuis Roel A Ophoff Katharine R Owen Chris J Packard Sandosh Padmanabhan Colin N A Palmer Nicholette D Palmer Gerard Pasterkamp Aniruddh P Patel Alison Pattie Oluf Pedersen Peggy L Peissig Gina M Peloso Craig E Pennell Markus Perola James A Perry John R B Perry Tune H Pers Thomas N Person Annette Peters Eva R B Petersen Patricia A Peyser Ailith Pirie Ozren Polasek Tinca J Polderman Hannu Puolijoki Olli T Raitakari Asif Rasheed Rainer Rauramaa Dermot F Reilly Frida Renström Myriam Rheinberger Paul M Ridker John D Rioux Manuel A Rivas David J Roberts Neil R Robertson Antonietta Robino Olov Rolandsson Igor Rudan Katherine S Ruth Danish Saleheen Veikko Salomaa Nilesh J Samani Yadav Sapkota Naveed Sattar Robert E Schoen Pamela J Schreiner Matthias B Schulze Robert A Scott Marcelo P Segura-Lepe Svati H Shah Wayne H-H Sheu Xueling Sim Andrew J Slater Kerrin S Small Albert V Smith Lorraine Southam Timothy D Spector Elizabeth K Speliotes John M Starr Kari Stefansson Valgerdur Steinthorsdottir Kathleen E Stirrups Konstantin Strauch Heather M Stringham Michael Stumvoll Liang Sun Praveen Surendran Amy J Swift Hayato Tada Katherine E Tansey Jean-Claude Tardif Kent D Taylor Alexander Teumer Deborah J Thompson Gudmar Thorleifsson Unnur Thorsteinsdottir Betina H Thuesen Anke Tönjes Gerard Tromp Stella Trompet Emmanouil Tsafantakis Jaakko Tuomilehto Anne Tybjaerg-Hansen Jonathan P Tyrer Rudolf Uher André G Uitterlinden Matti Uusitupa Sander W Laan Cornelia M Duijn Nienke Leeuwen Jessica van Setten Mauno Vanhala Anette Varbo Tibor V Varga Rohit Varma Digna R Velez Edwards Sita H Vermeulen Giovanni Veronesi Henrik Vestergaard Veronique Vitart Thomas F Vogt Uwe Völker Dragana Vuckovic Lynne E Wagenknecht Mark Walker Lars Wallentin Feijie Wang Carol A Wang Shuai Wang Yiqin Wang Erin B Ware Nicholas J Wareham Helen R Warren Dawn M Waterworth Jennifer Wessel Harvey D White Cristen J Willer James G Wilson Daniel R Witte Andrew R Wood Ying Wu Hanieh Yaghootkar Jie Yao Pang Yao Laura M Yerges-Armstrong Robin Young Eleftheria Zeggini Xiaowei Zhan Weihua Zhang Jing Hua Zhao Wei Zhao Wei Zhou Krina T Zondervan Jerome I Rotter John A Pospisilik Fernando Rivadeneira Ingrid B Borecki Panos Deloukas Timothy M Frayling Guillaume Lettre Kari E North Cecilia M Lindgren Joel N Hirschhorn Ruth J F Loos

Nat Genet 2018 05;50(5):765-766

Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1038/s41588-018-0050-yDOI Listing
May 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

Authors:
Valérie Turcot Yingchang Lu Heather M Highland Claudia Schurmann Anne E Justice Rebecca S Fine Jonathan P Bradfield Tõnu Esko Ayush Giri Mariaelisa Graff Xiuqing Guo Audrey E Hendricks Tugce Karaderi Adelheid Lempradl Adam E Locke Anubha Mahajan Eirini Marouli Suthesh Sivapalaratnam Kristin L Young Tamuno Alfred Mary F Feitosa Nicholas G D Masca Alisa K Manning Carolina Medina-Gomez Poorva Mudgal Maggie C Y Ng Alex P Reiner Sailaja Vedantam Sara M Willems Thomas W Winkler Gonçalo Abecasis Katja K Aben Dewan S Alam Sameer E Alharthi Matthew Allison Philippe Amouyel Folkert W Asselbergs Paul L Auer Beverley Balkau Lia E Bang Inês Barroso Lisa Bastarache Marianne Benn Sven Bergmann Lawrence F Bielak Matthias Blüher Michael Boehnke Heiner Boeing Eric Boerwinkle Carsten A Böger Jette Bork-Jensen Michiel L Bots Erwin P Bottinger Donald W Bowden Ivan Brandslund Gerome Breen Murray H Brilliant Linda Broer Marco Brumat Amber A Burt Adam S Butterworth Peter T Campbell Stefania Cappellani David J Carey Eulalia Catamo Mark J Caulfield John C Chambers Daniel I Chasman Yii-Der I Chen Rajiv Chowdhury Cramer Christensen Audrey Y Chu Massimiliano Cocca Francis S Collins James P Cook Janie Corley Jordi Corominas Galbany Amanda J Cox David S Crosslin Gabriel Cuellar-Partida Angela D'Eustacchio John Danesh Gail Davies Paul I W Bakker Mark C H Groot Renée Mutsert Ian J Deary George Dedoussis Ellen W Demerath Martin Heijer Anneke I Hollander Hester M Ruijter Joe G Dennis Josh C Denny Emanuele Di Angelantonio Fotios Drenos Mengmeng Du Marie-Pierre Dubé Alison M Dunning Douglas F Easton Todd L Edwards David Ellinghaus Patrick T Ellinor Paul Elliott Evangelos Evangelou Aliki-Eleni Farmaki I Sadaf Farooqi Jessica D Faul Sascha Fauser Shuang Feng Ele Ferrannini Jean Ferrieres Jose C Florez Ian Ford Myriam Fornage Oscar H Franco Andre Franke Paul W Franks Nele Friedrich Ruth Frikke-Schmidt Tessel E Galesloot Wei Gan Ilaria Gandin Paolo Gasparini Jane Gibson Vilmantas Giedraitis Anette P Gjesing Penny Gordon-Larsen Mathias Gorski Hans-Jörgen Grabe Struan F A Grant Niels Grarup Helen L Griffiths Megan L Grove Vilmundur Gudnason Stefan Gustafsson Jeff Haessler Hakon Hakonarson Anke R Hammerschlag Torben Hansen Kathleen Mullan Harris Tamara B Harris Andrew T Hattersley Christian T Have Caroline Hayward Liang He Nancy L Heard-Costa Andrew C Heath Iris M Heid Øyvind Helgeland Jussi Hernesniemi Alex W Hewitt Oddgeir L Holmen G Kees Hovingh Joanna M M Howson Yao Hu Paul L Huang Jennifer E Huffman M Arfan Ikram Erik Ingelsson Anne U Jackson Jan-Håkan Jansson Gail P Jarvik Gorm B Jensen Yucheng Jia Stefan Johansson Marit E Jørgensen Torben Jørgensen J Wouter Jukema Bratati Kahali René S Kahn Mika Kähönen Pia R Kamstrup Stavroula Kanoni Jaakko Kaprio Maria Karaleftheri Sharon L R Kardia Fredrik Karpe Sekar Kathiresan Frank Kee Lambertus A Kiemeney Eric Kim Hidetoshi Kitajima Pirjo Komulainen Jaspal S Kooner Charles Kooperberg Tellervo Korhonen Peter Kovacs Helena Kuivaniemi Zoltán Kutalik Kari Kuulasmaa Johanna Kuusisto Markku Laakso Timo A Lakka David Lamparter Ethan M Lange Leslie A Lange Claudia Langenberg Eric B Larson Nanette R Lee Terho Lehtimäki Cora E Lewis Huaixing Li Jin Li Ruifang Li-Gao Honghuang Lin Keng-Hung Lin Li-An Lin Xu Lin Lars Lind Jaana Lindström Allan Linneberg Ching-Ti Liu Dajiang J Liu Yongmei Liu Ken S Lo Artitaya Lophatananon Andrew J Lotery Anu Loukola Jian'an Luan Steven A Lubitz Leo-Pekka Lyytikäinen Satu Männistö Gaëlle Marenne Angela L Mazul Mark I McCarthy Roberta McKean-Cowdin Sarah E Medland Karina Meidtner Lili Milani Vanisha Mistry Paul Mitchell Karen L Mohlke Leena Moilanen Marie Moitry Grant W Montgomery Dennis O Mook-Kanamori Carmel Moore Trevor A Mori Andrew D Morris Andrew P Morris Martina Müller-Nurasyid Patricia B Munroe Mike A Nalls Narisu Narisu Christopher P Nelson Matt Neville Sune F Nielsen Kjell Nikus Pål R Njølstad Børge G Nordestgaard Dale R Nyholt Jeffrey R O'Connel Michelle L O'Donoghue Loes M Olde Loohuis Roel A Ophoff Katharine R Owen Chris J Packard Sandosh Padmanabhan Colin N A Palmer Nicholette D Palmer Gerard Pasterkamp Aniruddh P Patel Alison Pattie Oluf Pedersen Peggy L Peissig Gina M Peloso Craig E Pennell Markus Perola James A Perry John R B Perry Tune H Pers Thomas N Person Annette Peters Eva R B Petersen Patricia A Peyser Ailith Pirie Ozren Polasek Tinca J Polderman Hannu Puolijoki Olli T Raitakari Asif Rasheed Rainer Rauramaa Dermot F Reilly Frida Renström Myriam Rheinberger Paul M Ridker John D Rioux Manuel A Rivas David J Roberts Neil R Robertson Antonietta Robino Olov Rolandsson Igor Rudan Katherine S Ruth Danish Saleheen Veikko Salomaa Nilesh J Samani Yadav Sapkota Naveed Sattar Robert E Schoen Pamela J Schreiner Matthias B Schulze Robert A Scott Marcelo P Segura-Lepe Svati H Shah Wayne H-H Sheu Xueling Sim Andrew J Slater Kerrin S Small Albert V Smith Lorraine Southam Timothy D Spector Elizabeth K Speliotes John M Starr Kari Stefansson Valgerdur Steinthorsdottir Kathleen E Stirrups Konstantin Strauch Heather M Stringham Michael Stumvoll Liang Sun Praveen Surendran Amy J Swift Hayato Tada Katherine E Tansey Jean-Claude Tardif Kent D Taylor Alexander Teumer Deborah J Thompson Gudmar Thorleifsson Unnur Thorsteinsdottir Betina H Thuesen Anke Tönjes Gerard Tromp Stella Trompet Emmanouil Tsafantakis Jaakko Tuomilehto Anne Tybjaerg-Hansen Jonathan P Tyrer Rudolf Uher André G Uitterlinden Matti Uusitupa Sander W Laan Cornelia M Duijn Nienke Leeuwen Jessica van Setten Mauno Vanhala Anette Varbo Tibor V Varga Rohit Varma Digna R Velez Edwards Sita H Vermeulen Giovanni Veronesi Henrik Vestergaard Veronique Vitart Thomas F Vogt Uwe Völker Dragana Vuckovic Lynne E Wagenknecht Mark Walker Lars Wallentin Feijie Wang Carol A Wang Shuai Wang Yiqin Wang Erin B Ware Nicholas J Wareham Helen R Warren Dawn M Waterworth Jennifer Wessel Harvey D White Cristen J Willer James G Wilson Daniel R Witte Andrew R Wood Ying Wu Hanieh Yaghootkar Jie Yao Pang Yao Laura M Yerges-Armstrong Robin Young Eleftheria Zeggini Xiaowei Zhan Weihua Zhang Jing Hua Zhao Wei Zhao Wei Zhao Wei Zhou Krina T Zondervan Jerome I Rotter John A Pospisilik Fernando Rivadeneira Ingrid B Borecki Panos Deloukas Timothy M Frayling Guillaume Lettre Kari E North Cecilia M Lindgren Joel N Hirschhorn Ruth J F Loos

Nat Genet 2018 05;50(5):766-767

Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1038/s41588-018-0082-3DOI Listing
May 2018

Genes Associated with Thoracic Aortic Aneurysm and Dissection: 2018 Update and Clinical Implications.

Aorta (Stamford) 2018 Feb 27;6(1):13-20. Epub 2018 Jul 27.

Department of Surgery, Section of Cardiac Surgery, Aortic Institute at Yale-New Haven Hospital, Yale University School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1055/s-0038-1639612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136681PMC
February 2018

A review of genome-wide transcriptomics studies in Parkinson's disease.

Eur J Neurosci 2018 Jan 22;47(1):1-16. Epub 2017 Nov 22.

Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, PO Box 241, Cape Town, South Africa.

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http://dx.doi.org/10.1111/ejn.13760DOI Listing
January 2018

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

Authors:
Valérie Turcot Yingchang Lu Heather M Highland Claudia Schurmann Anne E Justice Rebecca S Fine Jonathan P Bradfield Tõnu Esko Ayush Giri Mariaelisa Graff Xiuqing Guo Audrey E Hendricks Tugce Karaderi Adelheid Lempradl Adam E Locke Anubha Mahajan Eirini Marouli Suthesh Sivapalaratnam Kristin L Young Tamuno Alfred Mary F Feitosa Nicholas G D Masca Alisa K Manning Carolina Medina-Gomez Poorva Mudgal Maggie C Y Ng Alex P Reiner Sailaja Vedantam Sara M Willems Thomas W Winkler Gonçalo Abecasis Katja K Aben Dewan S Alam Sameer E Alharthi Matthew Allison Philippe Amouyel Folkert W Asselbergs Paul L Auer Beverley Balkau Lia E Bang Inês Barroso Lisa Bastarache Marianne Benn Sven Bergmann Lawrence F Bielak Matthias Blüher Michael Boehnke Heiner Boeing Eric Boerwinkle Carsten A Böger Jette Bork-Jensen Michiel L Bots Erwin P Bottinger Donald W Bowden Ivan Brandslund Gerome Breen Murray H Brilliant Linda Broer Marco Brumat Amber A Burt Adam S Butterworth Peter T Campbell Stefania Cappellani David J Carey Eulalia Catamo Mark J Caulfield John C Chambers Daniel I Chasman Yii-Der I Chen Rajiv Chowdhury Cramer Christensen Audrey Y Chu Massimiliano Cocca Francis S Collins James P Cook Janie Corley Jordi Corominas Galbany Amanda J Cox David S Crosslin Gabriel Cuellar-Partida Angela D'Eustacchio John Danesh Gail Davies Paul I W Bakker Mark C H Groot Renée Mutsert Ian J Deary George Dedoussis Ellen W Demerath Martin Heijer Anneke I Hollander Hester M Ruijter Joe G Dennis Josh C Denny Emanuele Di Angelantonio Fotios Drenos Mengmeng Du Marie-Pierre Dubé Alison M Dunning Douglas F Easton Todd L Edwards David Ellinghaus Patrick T Ellinor Paul Elliott Evangelos Evangelou Aliki-Eleni Farmaki I Sadaf Farooqi Jessica D Faul Sascha Fauser Shuang Feng Ele Ferrannini Jean Ferrieres Jose C Florez Ian Ford Myriam Fornage Oscar H Franco Andre Franke Paul W Franks Nele Friedrich Ruth Frikke-Schmidt Tessel E Galesloot Wei Gan Ilaria Gandin Paolo Gasparini Jane Gibson Vilmantas Giedraitis Anette P Gjesing Penny Gordon-Larsen Mathias Gorski Hans-Jörgen Grabe Struan F A Grant Niels Grarup Helen L Griffiths Megan L Grove Vilmundur Gudnason Stefan Gustafsson Jeff Haessler Hakon Hakonarson Anke R Hammerschlag Torben Hansen Kathleen Mullan Harris Tamara B Harris Andrew T Hattersley Christian T Have Caroline Hayward Liang He Nancy L Heard-Costa Andrew C Heath Iris M Heid Øyvind Helgeland Jussi Hernesniemi Alex W Hewitt Oddgeir L Holmen G Kees Hovingh Joanna M M Howson Yao Hu Paul L Huang Jennifer E Huffman M Arfan Ikram Erik Ingelsson Anne U Jackson Jan-Håkan Jansson Gail P Jarvik Gorm B Jensen Yucheng Jia Stefan Johansson Marit E Jørgensen Torben Jørgensen J Wouter Jukema Bratati Kahali René S Kahn Mika Kähönen Pia R Kamstrup Stavroula Kanoni Jaakko Kaprio Maria Karaleftheri Sharon L R Kardia Fredrik Karpe Sekar Kathiresan Frank Kee Lambertus A Kiemeney Eric Kim Hidetoshi Kitajima Pirjo Komulainen Jaspal S Kooner Charles Kooperberg Tellervo Korhonen Peter Kovacs Helena Kuivaniemi Zoltán Kutalik Kari Kuulasmaa Johanna Kuusisto Markku Laakso Timo A Lakka David Lamparter Ethan M Lange Leslie A Lange Claudia Langenberg Eric B Larson Nanette R Lee Terho Lehtimäki Cora E Lewis Huaixing Li Jin Li Ruifang Li-Gao Honghuang Lin Keng-Hung Lin Li-An Lin Xu Lin Lars Lind Jaana Lindström Allan Linneberg Ching-Ti Liu Dajiang J Liu Yongmei Liu Ken S Lo Artitaya Lophatananon Andrew J Lotery Anu Loukola Jian'an Luan Steven A Lubitz Leo-Pekka Lyytikäinen Satu Männistö Gaëlle Marenne Angela L Mazul Mark I McCarthy Roberta McKean-Cowdin Sarah E Medland Karina Meidtner Lili Milani Vanisha Mistry Paul Mitchell Karen L Mohlke Leena Moilanen Marie Moitry Grant W Montgomery Dennis O Mook-Kanamori Carmel Moore Trevor A Mori Andrew D Morris Andrew P Morris Martina Müller-Nurasyid Patricia B Munroe Mike A Nalls Narisu Narisu Christopher P Nelson Matt Neville Sune F Nielsen Kjell Nikus Pål R Njølstad Børge G Nordestgaard Dale R Nyholt Jeffrey R O'Connel Michelle L O'Donoghue Loes M Olde Loohuis Roel A Ophoff Katharine R Owen Chris J Packard Sandosh Padmanabhan Colin N A Palmer Nicholette D Palmer Gerard Pasterkamp Aniruddh P Patel Alison Pattie Oluf Pedersen Peggy L Peissig Gina M Peloso Craig E Pennell Markus Perola James A Perry John R B Perry Tune H Pers Thomas N Person Annette Peters Eva R B Petersen Patricia A Peyser Ailith Pirie Ozren Polasek Tinca J Polderman Hannu Puolijoki Olli T Raitakari Asif Rasheed Rainer Rauramaa Dermot F Reilly Frida Renström Myriam Rheinberger Paul M Ridker John D Rioux Manuel A Rivas David J Roberts Neil R Robertson Antonietta Robino Olov Rolandsson Igor Rudan Katherine S Ruth Danish Saleheen Veikko Salomaa Nilesh J Samani Yadav Sapkota Naveed Sattar Robert E Schoen Pamela J Schreiner Matthias B Schulze Robert A Scott Marcelo P Segura-Lepe Svati H Shah Wayne H-H Sheu Xueling Sim Andrew J Slater Kerrin S Small Albert V Smith Lorraine Southam Timothy D Spector Elizabeth K Speliotes John M Starr Kari Stefansson Valgerdur Steinthorsdottir 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Yerges-Armstrong Robin Young Eleftheria Zeggini Xiaowei Zhan Weihua Zhang Jing Hua Zhao Wei Zhao Wei Zhao Wei Zhou Krina T Zondervan Jerome I Rotter John A Pospisilik Fernando Rivadeneira Ingrid B Borecki Panos Deloukas Timothy M Frayling Guillaume Lettre Kari E North Cecilia M Lindgren Joel N Hirschhorn Ruth J F Loos

Nat Genet 2018 01 22;50(1):26-41. Epub 2017 Dec 22.

Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1038/s41588-017-0011-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945951PMC
January 2018

Genetic risk models: Influence of model size on risk estimates and precision.

Genet Epidemiol 2017 05 15;41(4):282-296. Epub 2017 Feb 15.

Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.

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http://dx.doi.org/10.1002/gepi.22035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628612PMC
May 2017

Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.

Authors:
Philip C Haycock Stephen Burgess Aayah Nounu Jie Zheng George N Okoli Jack Bowden Kaitlin Hazel Wade Nicholas J Timpson David M Evans Peter Willeit Abraham Aviv Tom R Gaunt Gibran Hemani Massimo Mangino Hayley Patricia Ellis Kathreena M Kurian Karen A Pooley Rosalind A Eeles Jeffrey E Lee Shenying Fang Wei V Chen Matthew H Law Lisa M Bowdler Mark M Iles Qiong Yang Bradford B Worrall Hugh Stephen Markus Rayjean J Hung Chris I Amos Amanda B Spurdle Deborah J Thompson Tracy A O'Mara Brian Wolpin Laufey Amundadottir Rachael Stolzenberg-Solomon Antonia Trichopoulou N Charlotte Onland-Moret Eiliv Lund Eric J Duell Federico Canzian Gianluca Severi Kim Overvad Marc J Gunter Rosario Tumino Ulrika Svenson Andre van Rij Annette F Baas Matthew J Bown Nilesh J Samani Femke N G van t'Hof Gerard Tromp Gregory T Jones Helena Kuivaniemi James R Elmore Mattias Johansson James Mckay Ghislaine Scelo Robert Carreras-Torres Valerie Gaborieau Paul Brennan Paige M Bracci Rachel E Neale Sara H Olson Steven Gallinger Donghui Li Gloria M Petersen Harvey A Risch Alison P Klein Jiali Han Christian C Abnet Neal D Freedman Philip R Taylor John M Maris Katja K Aben Lambertus A Kiemeney Sita H Vermeulen John K Wiencke Kyle M Walsh Margaret Wrensch Terri Rice Clare Turnbull Kevin Litchfield Lavinia Paternoster Marie Standl Gonçalo R Abecasis John Paul SanGiovanni Yong Li Vladan Mijatovic Yadav Sapkota Siew-Kee Low Krina T Zondervan Grant W Montgomery Dale R Nyholt David A van Heel Karen Hunt Dan E Arking Foram N Ashar Nona Sotoodehnia Daniel Woo Jonathan Rosand Mary E Comeau W Mark Brown Edwin K Silverman John E Hokanson Michael H Cho Jennie Hui Manuel A Ferreira Philip J Thompson Alanna C Morrison Janine F Felix Nicholas L Smith Angela M Christiano Lynn Petukhova Regina C Betz Xing Fan Xuejun Zhang Caihong Zhu Carl D Langefeld Susan D Thompson Feijie Wang Xu Lin David A Schwartz Tasha Fingerlin Jerome I Rotter Mary Frances Cotch Richard A Jensen Matthias Munz Henrik Dommisch Arne S Schaefer Fang Han Hanna M Ollila Ryan P Hillary Omar Albagha Stuart H Ralston Chenjie Zeng Wei Zheng Xiao-Ou Shu Andre Reis Steffen Uebe Ulrike Hüffmeier Yoshiya Kawamura Takeshi Otowa Tsukasa Sasaki Martin Lloyd Hibberd Sonia Davila Gang Xie Katherine Siminovitch Jin-Xin Bei Yi-Xin Zeng Asta Försti Bowang Chen Stefano Landi Andre Franke Annegret Fischer David Ellinghaus Carlos Flores Imre Noth Shwu-Fan Ma Jia Nee Foo Jianjun Liu Jong-Won Kim David G Cox Olivier Delattre Olivier Mirabeau Christine F Skibola Clara S Tang Merce Garcia-Barcelo Kai-Ping Chang Wen-Hui Su Yu-Sun Chang Nicholas G Martin Scott Gordon Tracey D Wade Chaeyoung Lee Michiaki Kubo Pei-Chieng Cha Yusuke Nakamura Daniel Levy Masayuki Kimura Shih-Jen Hwang Steven Hunt Tim Spector Nicole Soranzo Ani W Manichaikul R Graham Barr Bratati Kahali Elizabeth Speliotes Laura M Yerges-Armstrong Ching-Yu Cheng Jost B Jonas Tien Yin Wong Isabella Fogh Kuang Lin John F Powell Kenneth Rice Caroline L Relton Richard M Martin George Davey Smith

JAMA Oncol 2017 May;3(5):636-651

MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England.

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http://dx.doi.org/10.1001/jamaoncol.2016.5945DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638008PMC
May 2017

and Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function.

Authors:
Man Li Yong Li Olivia Weeks Vladan Mijatovic Alexander Teumer Jennifer E Huffman Gerard Tromp Christian Fuchsberger Mathias Gorski Leo-Pekka Lyytikäinen Teresa Nutile Sanaz Sedaghat Rossella Sorice Adrienne Tin Qiong Yang Tarunveer S Ahluwalia Dan E Arking Nathan A Bihlmeyer Carsten A Böger Robert J Carroll Daniel I Chasman Marilyn C Cornelis Abbas Dehghan Jessica D Faul Mary F Feitosa Giovanni Gambaro Paolo Gasparini Franco Giulianini Iris Heid Jinyan Huang Medea Imboden Anne U Jackson Janina Jeff Min A Jhun Ronit Katz Annette Kifley Tuomas O Kilpeläinen Ashish Kumar Markku Laakso Ruifang Li-Gao Kurt Lohman Yingchang Lu Reedik Mägi Giovanni Malerba Evelin Mihailov Karen L Mohlke Dennis O Mook-Kanamori Antonietta Robino Douglas Ruderfer Erika Salvi Ursula M Schick Christina-Alexandra Schulz Albert V Smith Jennifer A Smith Michela Traglia Laura M Yerges-Armstrong Wei Zhao Mark O Goodarzi Aldi T Kraja Chunyu Liu Jennifer Wessel Eric Boerwinkle Ingrid B Borecki Jette Bork-Jensen Erwin P Bottinger Daniele Braga Ivan Brandslund Jennifer A Brody Archie Campbell David J Carey Cramer Christensen Josef Coresh Errol Crook Gary C Curhan Daniele Cusi Ian H de Boer Aiko P J de Vries Joshua C Denny Olivier Devuyst Albert W Dreisbach Karlhans Endlich Tõnu Esko Oscar H Franco Tibor Fulop Glenn S Gerhard Charlotte Glümer Omri Gottesman Niels Grarup Vilmundur Gudnason Torben Hansen Tamara B Harris Caroline Hayward Lynne Hocking Albert Hofman Frank B Hu Lise Lotte N Husemoen Rebecca D Jackson Torben Jørgensen Marit E Jørgensen Mika Kähönen Sharon L R Kardia Wolfgang König Charles Kooperberg Jennifer Kriebel Lenore J Launer Torsten Lauritzen Terho Lehtimäki Daniel Levy Pamela Linksted Allan Linneberg Yongmei Liu Ruth J F Loos Antonio Lupo Christine Meisinger Olle Melander Andres Metspalu Paul Mitchell Matthias Nauck Peter Nürnberg Marju Orho-Melander Afshin Parsa Oluf Pedersen Annette Peters Ulrike Peters Ozren Polasek David Porteous Nicole M Probst-Hensch Bruce M Psaty Lu Qi Olli T Raitakari Alex P Reiner Rainer Rettig Paul M Ridker Fernando Rivadeneira Jacques E Rossouw Frank Schmidt David Siscovick Nicole Soranzo Konstantin Strauch Daniela Toniolo Stephen T Turner André G Uitterlinden Sheila Ulivi Dinesh Velayutham Uwe Völker Henry Völzke Melanie Waldenberger Jie Jin Wang David R Weir Daniel Witte Helena Kuivaniemi Caroline S Fox Nora Franceschini Wolfram Goessling Anna Köttgen Audrey Y Chu

J Am Soc Nephrol 2017 Mar 5;28(3):981-994. Epub 2016 Dec 5.

National Heart, Lung, and Blood Institute's Framingham Heart Study and the Center for Population Studies, Framingham, Massachusetts;

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http://dx.doi.org/10.1681/ASN.2016020131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328154PMC
March 2017

Rare and low-frequency coding variants alter human adult height.

Authors:
Eirini Marouli Mariaelisa Graff Carolina Medina-Gomez Ken Sin Lo Andrew R Wood Troels R Kjaer Rebecca S Fine Yingchang Lu Claudia Schurmann Heather M Highland Sina Rüeger Gudmar Thorleifsson Anne E Justice David Lamparter Kathleen E Stirrups Valérie Turcot Kristin L Young Thomas W Winkler Tõnu Esko Tugce Karaderi Adam E Locke Nicholas G D Masca Maggie C Y Ng Poorva Mudgal Manuel A Rivas Sailaja Vedantam Anubha Mahajan Xiuqing Guo Goncalo Abecasis Katja K Aben Linda S Adair Dewan S Alam Eva Albrecht Kristine H Allin Matthew Allison Philippe Amouyel Emil V Appel Dominique Arveiler Folkert W Asselbergs Paul L Auer Beverley Balkau Bernhard Banas Lia E Bang Marianne Benn Sven Bergmann Lawrence F Bielak Matthias Blüher Heiner Boeing Eric Boerwinkle Carsten A Böger Lori L Bonnycastle Jette Bork-Jensen Michiel L Bots Erwin P Bottinger Donald W Bowden Ivan Brandslund Gerome Breen Murray H Brilliant Linda Broer Amber A Burt Adam S Butterworth David J Carey Mark J Caulfield John C Chambers Daniel I Chasman Yii-Der Ida Chen Rajiv Chowdhury Cramer Christensen Audrey Y Chu Massimiliano Cocca Francis S Collins James P Cook Janie Corley Jordi Corominas Galbany Amanda J Cox Gabriel Cuellar-Partida John Danesh Gail Davies Paul I W de Bakker Gert J de Borst Simon de Denus Mark C H de Groot Renée de Mutsert Ian J Deary George Dedoussis Ellen W Demerath Anneke I den Hollander Joe G Dennis Emanuele Di Angelantonio Fotios Drenos Mengmeng Du Alison M Dunning Douglas F Easton Tapani Ebeling Todd L Edwards Patrick T Ellinor Paul Elliott Evangelos Evangelou Aliki-Eleni Farmaki Jessica D Faul Mary F Feitosa Shuang Feng Ele Ferrannini Marco M Ferrario Jean Ferrieres Jose C Florez Ian Ford Myriam Fornage Paul W Franks Ruth Frikke-Schmidt Tessel E Galesloot Wei Gan Ilaria Gandin Paolo Gasparini Vilmantas Giedraitis Ayush Giri Giorgia Girotto Scott D Gordon Penny Gordon-Larsen Mathias Gorski Niels Grarup Megan L Grove Vilmundur Gudnason Stefan Gustafsson Torben Hansen Kathleen Mullan Harris Tamara B Harris Andrew T Hattersley Caroline Hayward Liang He Iris M Heid Kauko Heikkilä Øyvind Helgeland Jussi Hernesniemi Alex W Hewitt Lynne J Hocking Mette Hollensted Oddgeir L Holmen G Kees Hovingh Joanna M M Howson Carel B Hoyng Paul L Huang Kristian Hveem M Arfan Ikram Erik Ingelsson Anne U Jackson Jan-Håkan Jansson Gail P Jarvik Gorm B Jensen Min A Jhun Yucheng Jia Xuejuan Jiang Stefan Johansson Marit E Jørgensen Torben Jørgensen Pekka Jousilahti J Wouter Jukema Bratati Kahali René S Kahn Mika Kähönen Pia R Kamstrup Stavroula Kanoni Jaakko Kaprio Maria Karaleftheri Sharon L R Kardia Fredrik Karpe Frank Kee Renske Keeman Lambertus A Kiemeney Hidetoshi Kitajima Kirsten B Kluivers Thomas Kocher Pirjo Komulainen Jukka Kontto Jaspal S Kooner Charles Kooperberg Peter Kovacs Jennifer Kriebel Helena Kuivaniemi Sébastien Küry Johanna Kuusisto Martina La Bianca Markku Laakso Timo A Lakka Ethan M Lange Leslie A Lange Carl D Langefeld Claudia Langenberg Eric B Larson I-Te Lee Terho Lehtimäki Cora E Lewis Huaixing Li Jin Li Ruifang Li-Gao Honghuang Lin Li-An Lin Xu Lin Lars Lind Jaana Lindström Allan Linneberg Yeheng Liu Yongmei Liu Artitaya Lophatananon Jian'an Luan Steven A Lubitz Leo-Pekka Lyytikäinen David A Mackey Pamela A F Madden Alisa K Manning Satu Männistö Gaëlle Marenne Jonathan Marten Nicholas G Martin Angela L Mazul Karina Meidtner Andres Metspalu Paul Mitchell Karen L Mohlke Dennis O Mook-Kanamori Anna Morgan Andrew D Morris Andrew P Morris Martina Müller-Nurasyid Patricia B Munroe Mike A Nalls Matthias Nauck Christopher P Nelson Matt Neville Sune F Nielsen Kjell Nikus Pål R Njølstad Børge G Nordestgaard Ioanna Ntalla Jeffrey R O'Connel Heikki Oksa Loes M Olde Loohuis Roel A Ophoff Katharine R Owen Chris J Packard Sandosh Padmanabhan Colin N A Palmer Gerard Pasterkamp Aniruddh P Patel Alison Pattie Oluf Pedersen Peggy L Peissig Gina M Peloso Craig E Pennell Markus Perola James A Perry John R B Perry Thomas N Person Ailith Pirie Ozren Polasek Danielle Posthuma Olli T Raitakari Asif Rasheed Rainer Rauramaa Dermot F Reilly Alex P Reiner Frida Renström Paul M Ridker John D Rioux Neil Robertson Antonietta Robino Olov Rolandsson Igor Rudan Katherine S Ruth Danish Saleheen Veikko Salomaa Nilesh J Samani Kevin Sandow Yadav Sapkota Naveed Sattar Marjanka K Schmidt Pamela J Schreiner Matthias B Schulze Robert A Scott Marcelo P Segura-Lepe Svati Shah Xueling Sim Suthesh Sivapalaratnam Kerrin S Small Albert Vernon Smith Jennifer A Smith Lorraine Southam Timothy D Spector Elizabeth K Speliotes John M Starr Valgerdur Steinthorsdottir Heather M Stringham Michael Stumvoll Praveen Surendran Leen M 't Hart Katherine E Tansey Jean-Claude Tardif Kent D Taylor Alexander Teumer Deborah J Thompson Unnur Thorsteinsdottir Betina H Thuesen Anke Tönjes Gerard Tromp Stella Trompet Emmanouil Tsafantakis Jaakko Tuomilehto Anne Tybjaerg-Hansen Jonathan P Tyrer Rudolf Uher André G Uitterlinden Sheila Ulivi Sander W van der Laan Andries R Van Der Leij Cornelia M van Duijn Natasja M van Schoor Jessica van Setten Anette Varbo Tibor V Varga Rohit Varma Digna R Velez Edwards Sita H Vermeulen Henrik Vestergaard Veronique Vitart Thomas F Vogt Diego Vozzi Mark Walker Feijie Wang Carol A Wang Shuai Wang Yiqin Wang Nicholas J Wareham Helen R Warren Jennifer Wessel Sara M Willems James G Wilson Daniel R Witte Michael O Woods Ying Wu Hanieh Yaghootkar Jie Yao Pang Yao Laura M Yerges-Armstrong Robin Young Eleftheria Zeggini Xiaowei Zhan Weihua Zhang Jing Hua Zhao Wei Zhao Wei Zhao He Zheng Wei Zhou Jerome I Rotter Michael Boehnke Sekar Kathiresan Mark I McCarthy Cristen J Willer Kari Stefansson Ingrid B Borecki Dajiang J Liu Kari E North Nancy L Heard-Costa Tune H Pers Cecilia M Lindgren Claus Oxvig Zoltán Kutalik Fernando Rivadeneira Ruth J F Loos Timothy M Frayling Joel N Hirschhorn Panos Deloukas Guillaume Lettre

Nature 2017 02 1;542(7640):186-190. Epub 2017 Feb 1.

Montreal Heart Institute, Montreal, Quebec H1T 1C8, Canada.

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http://dx.doi.org/10.1038/nature21039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302847PMC
February 2017

Genes Associated with Thoracic Aortic Aneurysm and Dissection: An Update and Clinical Implications.

Aorta (Stamford) 2017 Feb 1;5(1):11-20. Epub 2017 Feb 1.

Aortic Institute at Yale-New Haven Hospital, Yale University School of Medicine, New Haven, Connecticut, USA.

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http://dx.doi.org/10.12945/j.aorta.2017.17.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570562PMC
February 2017

Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci.

Authors:
Gregory T Jones Gerard Tromp Helena Kuivaniemi Solveig Gretarsdottir Annette F Baas Betti Giusti Ewa Strauss Femke N G Van't Hof Thomas R Webb Robert Erdman Marylyn D Ritchie James R Elmore Anurag Verma Sarah Pendergrass Iftikhar J Kullo Zi Ye Peggy L Peissig Omri Gottesman Shefali S Verma Jennifer Malinowski Laura J Rasmussen-Torvik Kenneth M Borthwick Diane T Smelser David R Crosslin Mariza de Andrade Evan J Ryer Catherine A McCarty Erwin P Böttinger Jennifer A Pacheco Dana C Crawford David S Carrell Glenn S Gerhard David P Franklin David J Carey Victoria L Phillips Michael J A Williams Wenhua Wei Ross Blair Andrew A Hill Thodor M Vasudevan David R Lewis Ian A Thomson Jo Krysa Geraldine B Hill Justin Roake Tony R Merriman Grzegorz Oszkinis Silvia Galora Claudia Saracini Rosanna Abbate Raffaele Pulli Carlo Pratesi Athanasios Saratzis Ana R Verissimo Suzannah Bumpstead Stephen A Badger Rachel E Clough Gillian Cockerill Hany Hafez D Julian A Scott T Simon Futers Simon P R Romaine Katherine Bridge Kathryn J Griffin Marc A Bailey Alberto Smith Matthew M Thompson Frank M van Bockxmeer Stefan E Matthiasson Gudmar Thorleifsson Unnur Thorsteinsdottir Jan D Blankensteijn Joep A W Teijink Cisca Wijmenga Jacqueline de Graaf Lambertus A Kiemeney Jes S Lindholt Anne Hughes Declan T Bradley Kathleen Stirrups Jonathan Golledge Paul E Norman Janet T Powell Steve E Humphries Stephen E Hamby Alison H Goodall Christopher P Nelson Natzi Sakalihasan Audrey Courtois Robert E Ferrell Per Eriksson Lasse Folkersen Anders Franco-Cereceda John D Eicher Andrew D Johnson Christer Betsholtz Arno Ruusalepp Oscar Franzén Eric E Schadt Johan L M Björkegren Leonard Lipovich Anne M Drolet Eric L Verhoeven Clark J Zeebregts Robert H Geelkerken Marc R van Sambeek Steven M van Sterkenburg Jean-Paul de Vries Kari Stefansson John R Thompson Paul I W de Bakker Panos Deloukas Robert D Sayers Seamus C Harrison Andre M van Rij Nilesh J Samani Matthew J Bown

Circ Res 2017 Jan 29;120(2):341-353. Epub 2016 Nov 29.

For the author affiliations, please see the Appendix.

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http://dx.doi.org/10.1161/CIRCRESAHA.116.308765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253231PMC
January 2017

eMERGE Phenome-Wide Association Study (PheWAS) identifies clinical associations and pleiotropy for stop-gain variants.

BMC Med Genomics 2016 08 12;9 Suppl 1:32. Epub 2016 Aug 12.

Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, 7505, South Africa.

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http://dx.doi.org/10.1186/s12920-016-0191-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989894PMC
August 2016

Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms.

J Am Heart Assoc 2016 07 14;5(7). Epub 2016 Jul 14.

Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands

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http://dx.doi.org/10.1161/JAHA.115.002603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015357PMC
July 2016

Understanding the pathogenesis of abdominal aortic aneurysms.

Expert Rev Cardiovasc Ther 2015 ;13(9):975-87

a 1 Sigfried and Janet Weis Center for Research, Geisinger Health System, Danville, PA 17822, USA.

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http://dx.doi.org/10.1586/14779072.2015.1074861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829576PMC
February 2016

In response: abdominal aortic aneurysms: do not underestimate the role of diabetes.

Expert Rev Cardiovasc Ther 2015 Dec 15;13(12):1291-2. Epub 2015 Oct 15.

a Sigfried and Janet Weis Center for Research , Geisinger Health System , Danville , PA 17822 , USA.

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http://dx.doi.org/10.1586/14779072.2015.1100538DOI Listing
December 2015

Proinflammatory role of stem cells in abdominal aortic aneurysms.

J Vasc Surg 2015 Nov 3;62(5):1303-11.e4. Epub 2014 Jul 3.

Sigfried and Janet Weis Center for Research, Geisinger Health System, Danville, Pa.

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http://dx.doi.org/10.1016/j.jvs.2014.04.067DOI Listing
November 2015

Patients with familial abdominal aortic aneurysms are at increased risk for endoleak and secondary intervention following elective endovascular aneurysm repair.

J Vasc Surg 2015 Nov 5;62(5):1119-24.e9. Epub 2015 Aug 5.

Department of Endovascular and Vascular Surgery, Geisinger Medical Center, Danville, Pa.

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http://dx.doi.org/10.1016/j.jvs.2015.06.205DOI Listing
November 2015

Immunohistochemical analysis of the natural killer cell cytotoxicity pathway in human abdominal aortic aneurysms.

Int J Mol Sci 2015 May 18;16(5):11196-212. Epub 2015 May 18.

Sigfried and Janet Weis Center for Research, Geisinger Health System, Danville, PA 17822, USA.

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http://dx.doi.org/10.3390/ijms160511196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463696PMC
May 2015

Transcriptional (ChIP-Chip) Analysis of ELF1, ETS2, RUNX1 and STAT5 in Human Abdominal Aortic Aneurysm.

Int J Mol Sci 2015 May 18;16(5):11229-58. Epub 2015 May 18.

Sigfried and Janet Weis Center for Research, Geisinger Health System, Danville, PA 17822, USA.

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http://dx.doi.org/10.3390/ijms160511229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463698PMC
May 2015

The foundation of precision medicine: integration of electronic health records with genomics through basic, clinical, and translational research.

Front Genet 2015 17;6:104. Epub 2015 Mar 17.

The Sigfried and Janet Weis Center for Research, Geisinger Health System Danville, PA, USA ; Department of Surgery, Temple University School of Medicine Philadelphia, PA, USA.

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http://dx.doi.org/10.3389/fgene.2015.00104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362332PMC
April 2015

Expanding Horizons for Abdominal Aortic Aneurysms.

Aorta (Stamford) 2015 Feb 1;3(1):9-15. Epub 2015 Feb 1.

The Sigfried and Janet Weis Center for Research, Geisinger Health System, Danville, Pennsylvania, USA; Department of Surgery, Temple University School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.12945/j.aorta.2015.14-041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714933PMC
February 2015

Molecular basis and genetic predisposition to intracranial aneurysm.

Ann Med 2014 Dec 12;46(8):597-606. Epub 2014 Aug 12.

The Sigfried and Janet Weis Center for Research, Geisinger Health System , Danville, Pennsylvania , USA.

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http://dx.doi.org/10.3109/07853890.2014.949299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438354PMC
December 2014

Regulatory polymorphisms in human DBH affect peripheral gene expression and sympathetic activity.

Circ Res 2014 Dec 17;115(12):1017-25. Epub 2014 Oct 17.

From the Center for Pharmacogenomics, College of Medicine, The Ohio State University, Columbus (E.S.B., J.K.P., W.S.); Department of Human Genetics, Emory University School of Medicine, Atlanta, GA (D.W., J.F.C.); Center for Systems Genomics, Pennsylvania State University, University Park (A.V., S.A.P., M.D.R.); Department of Genetics, University of North Carolina School of Medicine, Chapel Hill (L.A.L.); Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson (J.G.W.); The Sigfried and Janet Weis Center for Research, Geisinger Health System, Danville, PA (H.K., G.T., D.J.C.); Institute for Personalized Medicine, The Pennsylvania State University College of Medicine, Hershey (G.S.G.); Center for Human Genetics, Marshfield Clinic Research Foundation, WI (M.H.B., S.J.H.); and Department of Psychology, The University of Chicago, IL (G.J.N.).

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http://dx.doi.org/10.1161/CIRCRESAHA.116.304398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258174PMC
December 2014

Population risk factor estimates for abdominal aortic aneurysm from electronic medical records: a case control study.

BMC Cardiovasc Disord 2014 Dec 4;14:174. Epub 2014 Dec 4.

Sigfried and Janet Weis Center for Research, Geisinger Health System, Danville, PA, USA.

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http://dx.doi.org/10.1186/1471-2261-14-174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269847PMC
December 2014

Sex differences in abdominal aortic aneurysm: the role of sex hormones.

Ann Vasc Surg 2014 Nov 6;28(8):1946-58. Epub 2014 Aug 6.

Department of Cardiovascular Surgery, Surgical Research Center, GIGA-Cardiovascular Unit, University Hospital of Liège, Liège, Belgium; Department of Cardiovascular Surgery, University Hospital of Liège, Liège, Belgium.

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http://dx.doi.org/10.1016/j.avsg.2014.07.008DOI Listing
November 2014

Pharmacological inhibitor of notch signaling stabilizes the progression of small abdominal aortic aneurysm in a mouse model.

J Am Heart Assoc 2014 Oct 27;3(6):e001064. Epub 2014 Oct 27.

Center for Cardiovascular and Pulmonary Research and The Heart Center, Nationwide Children's Hospital, The Ohio State University, Columbus, OH (J.C., S.N.K., V.G., C.P.H.) Department of Pediatrics, The Ohio State University, Columbus, OH (V.G., C.P.H.).

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http://dx.doi.org/10.1161/JAHA.114.001064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338693PMC
October 2014

eMERGEing progress in genomics-the first seven years.

Front Genet 2014 17;5:184. Epub 2014 Jun 17.

Department of Biochemistry and Molecular Biology, Pennsylvania State University University Park, PA, USA ; Center for Systems Genomics, Pennsylvania State University University Park, PA, USA.

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http://journal.frontiersin.org/article/10.3389/fgene.2014.00
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http://dx.doi.org/10.3389/fgene.2014.00184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060012PMC
July 2014

Update on abdominal aortic aneurysm research: from clinical to genetic studies.

Scientifica (Cairo) 2014 17;2014:564734. Epub 2014 Apr 17.

The Sigfried and Janet Weis Center for Research, Geisinger Health System, Danville, PA, USA.

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http://dx.doi.org/10.1155/2014/564734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009235PMC
June 2014

Family members of patients with abdominal aortic aneurysms are at increased risk for aneurysms: analysis of 618 probands and their families from the Liège AAA Family Study.

Ann Vasc Surg 2014 May 21;28(4):787-97. Epub 2013 Dec 21.

The Sigfried and Janet Weis Center for Research, Geisinger Health System, Danville, PA; Department of Surgery, Temple University School of Medicine, Philadelphia, PA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08905096130068
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http://dx.doi.org/10.1016/j.avsg.2013.11.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082690PMC
May 2014

The association of genetic variants of matrix metalloproteinases with abdominal aortic aneurysm: a systematic review and meta-analysis.

Heart 2014 Feb 27;100(4):295-302. Epub 2013 Jun 27.

Queensland Research Centre for Peripheral Vascular Disease, School of Medicine and Dentistry, James Cook University, , Townsville, Queensland, Australia.

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http://heart.bmj.com/content/100/4/295.full.pdf
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http://heart.bmj.com/lookup/doi/10.1136/heartjnl-2013-304129
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http://dx.doi.org/10.1136/heartjnl-2013-304129DOI Listing
February 2014

MicroRNA analysis in placentas from patients with preeclampsia: comparison of new and published results.

Hypertens Pregnancy 2013 Nov 11;32(4):321-39. Epub 2013 Jul 11.

Department of Maternal Fetal Medicine, Geisinger Clinic , Danville, PA , USA .

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http://dx.doi.org/10.3109/10641955.2013.807819DOI Listing
November 2013

Genetics of abdominal aortic aneurysm.

Curr Opin Cardiol 2013 May;28(3):290-6

The Vascular Biology Unit, Queensland Research Centre for Peripheral Vascular Disease, School of Medicine and Dentistry, James Cook University, Townsville, Australia.

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http://dx.doi.org/10.1097/HCO.0b013e32835f0d55DOI Listing
May 2013

Inhibition of Notch1 signaling reduces abdominal aortic aneurysm in mice by attenuating macrophage-mediated inflammation.

Arterioscler Thromb Vasc Biol 2012 Dec 18;32(12):3012-23. Epub 2012 Oct 18.

Center for Cardiovascular and Pulmonary Research and The Heart Center, Nationwide Children’s Hospital, Columbus, OH 43205, USA.

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http://dx.doi.org/10.1161/ATVBAHA.112.254219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467024PMC
December 2012

Opportunities in abdominal aortic aneurysm research: epidemiology, genetics, and pathophysiology.

Ann Vasc Surg 2012 Aug;26(6):862-70

Department of Vascular and Endovascular Surgery, The Sigfried and Janet Weis Center for Research, Geisinger Clinic, Danville, PA 17822-2610, USA.

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http://dx.doi.org/10.1016/j.avsg.2012.02.005DOI Listing
August 2012

Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism.

J Am Coll Cardiol 2012 Aug;60(8):722-9

Population Genomics, deCODE Genetics, Reykjavik, Iceland.

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http://dx.doi.org/10.1016/j.jacc.2012.01.078DOI Listing
August 2012

MicroRNA expression signature in human abdominal aortic aneurysms.

BMC Med Genomics 2012 Jun 15;5:25. Epub 2012 Jun 15.

The Sigfried and Janet Weis Center for Research, Geisinger Clinic, 100 North Academy Avenue, Pennsylvania 17822-2610, USA.

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http://dx.doi.org/10.1186/1755-8794-5-25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507654PMC
June 2012

Genes and abdominal aortic aneurysm.

Ann Vasc Surg 2011 Apr 13;25(3):388-412. Epub 2010 Dec 13.

Geisinger Health System, The Sigfried and Janet Weis Center for Research, 100 North Academy Avenue, Danville, PA 17822-2610, USA.

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http://dx.doi.org/10.1016/j.avsg.2010.09.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058859PMC
April 2011

Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm.

Authors:
Solveig Gretarsdottir Annette F Baas Gudmar Thorleifsson Hilma Holm Martin den Heijer Jean-Paul P M de Vries Steef E Kranendonk Clark J A M Zeebregts Steven M van Sterkenburg Robert H Geelkerken Andre M van Rij Michael J A Williams Albert P M Boll Jelena P Kostic Adalbjorg Jonasdottir Aslaug Jonasdottir G Bragi Walters Gisli Masson Patrick Sulem Jona Saemundsdottir Magali Mouy Kristinn P Magnusson Gerard Tromp James R Elmore Natzi Sakalihasan Raymond Limet Jean-Olivier Defraigne Robert E Ferrell Antti Ronkainen Ynte M Ruigrok Cisca Wijmenga Diederick E Grobbee Svati H Shah Christopher B Granger Arshed A Quyyumi Viola Vaccarino Riyaz S Patel A Maziar Zafari Allan I Levey Harland Austin Domenico Girelli Pier Franco Pignatti Oliviero Olivieri Nicola Martinelli Giovanni Malerba Elisabetta Trabetti Lewis C Becker Diane M Becker Muredach P Reilly Daniel J Rader Thomas Mueller Benjamin Dieplinger Meinhard Haltmayer Sigitas Urbonavicius Bengt Lindblad Anders Gottsäter Eleonora Gaetani Roberto Pola Philip Wells Marc Rodger Melissa Forgie Nicole Langlois Javier Corral Vicente Vicente Jordi Fontcuberta Francisco España Niels Grarup Torben Jørgensen Daniel R Witte Torben Hansen Oluf Pedersen Katja K Aben Jacqueline de Graaf Suzanne Holewijn Lasse Folkersen Anders Franco-Cereceda Per Eriksson David A Collier Hreinn Stefansson Valgerdur Steinthorsdottir Thorunn Rafnar Einar M Valdimarsson Hulda B Magnadottir Sigurlaug Sveinbjornsdottir Isleifur Olafsson Magnus Karl Magnusson Robert Palmason Vilhelmina Haraldsdottir Karl Andersen Pall T Onundarson Gudmundur Thorgeirsson Lambertus A Kiemeney Janet T Powell David J Carey Helena Kuivaniemi Jes S Lindholt Gregory T Jones Augustine Kong Jan D Blankensteijn Stefan E Matthiasson Unnur Thorsteinsdottir Kari Stefansson

Nat Genet 2010 Aug 11;42(8):692-7. Epub 2010 Jul 11.

Population Genomics, deCODE Genetics, Reykjavik, Iceland.

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http://dx.doi.org/10.1038/ng.622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157066PMC
August 2010

Novel genetic mechanisms for aortic aneurysms.

Curr Atheroscler Rep 2010 Jul;12(4):259-66

Sigfried and Janet Weis Center for Research, Geisinger Clinic, Danville, PA 17822-2611, USA.

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http://dx.doi.org/10.1007/s11883-010-0111-xDOI Listing
July 2010

The role of complement Factor H in age-related macular degeneration: a review.

Surv Ophthalmol 2010 May-Jun;55(3):227-46

The Philadelphia Retina Endowment Fund, The Eye Research Institute, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.survophthal.2009.11.001DOI Listing
May 2010

Klf15 deficiency is a molecular link between heart failure and aortic aneurysm formation.

Sci Transl Med 2010 Apr;2(26):26ra26

Case Cardiovascular Research Institute, Department of Medicine, Harrington-McLaughlin Heart and Vascular Institute, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1126/scitranslmed.3000502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003709PMC
April 2010

Binding sites for ETS family of transcription factors dominate the promoter regions of differentially expressed genes in abdominal aortic aneurysms.

Circ Cardiovasc Genet 2009 Dec 19;2(6):565-72. Epub 2009 Oct 19.

Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, Michigan,USA.

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http://dx.doi.org/10.1161/CIRCGENETICS.108.843854DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089770PMC
December 2009

Identification of a genetic variant associated with abdominal aortic aneurysms on chromosome 3p12.3 by genome wide association.

J Vasc Surg 2009 Jun;49(6):1525-31

Department of Vascular and Endovascular Surgery, Geisinger Clinic, Danville, PA 17822-2601, USA.

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http://dx.doi.org/10.1016/j.jvs.2009.01.041DOI Listing
June 2009

Analytical approaches to detect maternal/fetal genotype incompatibilities that increase risk of pre-eclampsia.

BMC Med Genet 2008 Jul 3;9:60. Epub 2008 Jul 3.

Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH, USA.

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http://dx.doi.org/10.1186/1471-2350-9-60DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2474585PMC
July 2008

Basic research studies to understand aneurysm disease.

Drug News Perspect 2008 Apr;21(3):142-8

Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, Michigan 48201, USA.

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April 2008

The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm.

Nat Genet 2008 Feb 6;40(2):217-24. Epub 2008 Jan 6.

deCODE Genetics, Sturlugata 8, IS-101 Reykjavik, Iceland.

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http://dx.doi.org/10.1038/ng.72DOI Listing
February 2008

Aortic aneurysms: an immune disease with a strong genetic component.

Circulation 2008 Jan;117(2):242-52

Center for Molecular Medicine and Genetics and Department of Surgery, Wayne State University School of Medicine, 540 E Canfield Ave, Detroit, MI 48201, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.107.690982DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001294PMC
January 2008

Integration of expression profiles and genetic mapping data to identify candidate genes in intracranial aneurysm.

Physiol Genomics 2007 Dec 18;32(1):45-57. Epub 2007 Sep 18.

Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI 48201, USA.

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http://dx.doi.org/10.1152/physiolgenomics.00015.2007DOI Listing
December 2007

Mutations in the UBIAD1 gene on chromosome short arm 1, region 36, cause Schnyder crystalline corneal dystrophy.

Invest Ophthalmol Vis Sci 2007 Nov;48(11):5007-12

Kresge Eye Institute, The Department of Ophthalmology, Wayne State University School of Medicine, Detroit, MI 48201, USA.

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http://dx.doi.org/10.1167/iovs.07-0845DOI Listing
November 2007

Association of kallikrein gene polymorphisms with intracranial aneurysms.

Stroke 2007 Oct 30;38(10):2670-6. Epub 2007 Aug 30.

Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, 3309 Gordon H. Scott Hall of Basic Medical Sciences, 540 East Canfield Avenue, Detroit, MI 48201, USA.

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http://dx.doi.org/10.1161/STROKEAHA.107.486225DOI Listing
October 2007

Whole genome expression profiling reveals a significant role for immune function in human abdominal aortic aneurysms.

BMC Genomics 2007 Jul 16;8:237. Epub 2007 Jul 16.

Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI, USA.

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http://dx.doi.org/10.1186/1471-2164-8-237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1934369PMC
July 2007

Role of matrix metalloproteinase inhibitors in preventing abdominal aortic aneurysm.

Ann Vasc Surg 2007 May;21(3):392-401

Department of Surgery, New York Medical College, Valhalla, NY, USA.

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http://dx.doi.org/10.1016/j.avsg.2006.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2128752PMC
May 2007

Challenges and opportunities in abdominal aortic aneurysm research.

J Vasc Surg 2007 Jan;45(1):192-8

National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1016/j.jvs.2006.09.004DOI Listing
January 2007

Genome-wide approach to finding abdominal aortic aneurysm susceptibility genes in humans.

Ann N Y Acad Sci 2006 Nov;1085:270-81

Center for Molecular Medicine and Genetics and Department of Surgery, Wayne State University School of Medicine, 3317 Gordon H. Scott Hall of Basic Medical Sciences, 540 E. Canfield Ave., Detroit, MI 48201, USA.

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http://dx.doi.org/10.1196/annals.1383.022DOI Listing
November 2006

Global expression profiles in human normal and aneurysmal abdominal aorta based on two distinct whole genome microarray platforms.

Ann N Y Acad Sci 2006 Nov;1085:360-2

Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, 3317 Gordon H. Scott Hall of Basic Medical Sciences, 540 E. Canfield Ave., Detroit, MI 48201, USA.

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http://dx.doi.org/10.1196/annals.1383.041DOI Listing
November 2006

HLA-DQA is associated with abdominal aortic aneurysms in the Belgian population.

Ann N Y Acad Sci 2006 Nov;1085:392-5

Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, 3317 Gordon H. Scott Hall of Basic Medical Sciences, 540 E. Canfield Ave., Detroit, MI 48201, USA.

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http://dx.doi.org/10.1196/annals.1383.045DOI Listing
November 2006

A new mutation in exon 3 of the SCL39A4 gene in a Tunisian family with severe acrodermatitis enteropathica.

Nutrition 2006 Oct 2;22(10):1067-70. Epub 2006 Aug 2.

Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, Michigan, USA.

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http://dx.doi.org/10.1016/j.nut.2006.05.008DOI Listing
October 2006

A functional SNP in the promoter of the SERPINH1 gene increases risk of preterm premature rupture of membranes in African Americans.

Proc Natl Acad Sci U S A 2006 Sep 28;103(36):13463-7. Epub 2006 Aug 28.

Center for Research on Reproduction and Women's Health and Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1073/pnas.0603676103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1557384PMC
September 2006

Human spontaneous labor without histologic chorioamnionitis is characterized by an acute inflammation gene expression signature.

Am J Obstet Gynecol 2006 Aug;195(2):394.e1-24

The Perinatology Research Branch, National Institute of Child Health and Human Development, NIH, DHHS, Bethesda, MD, USA.

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http://dx.doi.org/10.1016/j.ajog.2005.08.057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1800883PMC
August 2006

Identification of novel functional sequence variants in the gene for peptidase inhibitor 3.

BMC Med Genet 2006 May 23;7:49. Epub 2006 May 23.

Center of Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI, USA.

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http://dx.doi.org/10.1186/1471-2350-7-49DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1508140PMC
May 2006

Community-based, nonprofit organization-sponsored ultrasonography screening program for abdominal aortic aneurysms is effective at identifying occult aneurysms.

Ann Vasc Surg 2006 May 27;20(3):312-6. Epub 2006 Apr 27.

Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI 48201, USA.

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http://dx.doi.org/10.1007/s10016-006-9056-5DOI Listing
May 2006

Macrophage migration inhibitory factor in patients with preterm parturition and microbial invasion of the amniotic cavity.

J Matern Fetal Neonatal Med 2005 Dec;18(6):405-16

Perinatology Research Branch, National Institute of Child Health and Human Development, NIH/DHHS, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1080/14767050500361703DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1383603PMC
December 2005

Expression of bone morphogenetic protein 2 in normal spontaneous labor at term, preterm labor, and preterm premature rupture of membranes.

Am J Obstet Gynecol 2005 Sep;193(3 Pt 2):1137-43

Perinatology Research Branch, National Institute of Child Health and Human Development/National Institutes of Health/Department of Health and Human Services, Bethesda, MD, USA.

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http://dx.doi.org/10.1016/j.ajog.2005.06.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1351231PMC
September 2005