Helen Sang

Roslin Institute Chicken Embryology, Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom.

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February 2019

A chicken bioreactor for efficient production of functional cytokines.

Authors:

Lissa R Herron Clare Pridans Matthew L Turnbull Nikki Smith Simon Lillico Adrian Sherman Hazel J Gilhooley Martin Wear Dominic Kurian Grigorios Papadakos Paul Digard David A Hume Andrew C Gill Helen M Sang

BMC Biotechnol 2018 12 29;18(1):82. Epub 2018 Dec 29.

The Roslin Institute, University of Edinburgh, Easter Bush, Midlothian, EH25 9RG, UK.

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December 2018

Livestock 2.0 - genome editing for fitter, healthier, and more productive farmed animals.

Authors:

Christine Tait-Burkard Andrea Doeschl-Wilson Mike J McGrew Alan L Archibald Helen M Sang Ross D Houston C Bruce Whitelaw Mick Watson

Genome Biol 2018 11 26;19(1):204. Epub 2018 Nov 26.

The Roslin Institute and R(D)SVS, University of Edinburgh, Easter Bush, Midlothian, EH25 9RG, UK.

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November 2018

High fidelity CRISPR/Cas9 increases precise monoallelic and biallelic editing events in primordial germ cells.

Authors:

Alewo Idoko-Akoh Lorna Taylor Helen M Sang Michael J McGrew

Sci Rep 2018 10 11;8(1):15126. Epub 2018 Oct 11.

The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush Campus, Midlothian, EH25 9RG, UK.

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October 2018

Mib1 prevents Notch Cis-inhibition to defer differentiation and preserve neuroepithelial integrity during neural delamination.

Authors:

Chooyoung Baek Lucy Freem Rosette Goïame Helen Sang Xavier Morin Samuel Tozer

PLoS Biol 2018 04 30;16(4):e2004162. Epub 2018 Apr 30.

Cell Division and Neurogenesis, Institut de Biologie de l'Ecole Normale Supérieure (IBENS), Ecole Normale Supérieure, CNRS, Inserm, PSL Université Paris, Paris, France.

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April 2018

Illuminating the chicken model through genetic modification.

Authors:

Megan G Davey Adam Balic Joe Rainger Helen M Sang Michael J McGrew

Int J Dev Biol 2018 ;62(1-2-3):257-264

Roslin Institute Chicken Embryology (RICE), The Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh, Midlothian, UK.

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April 2019

Genome Editing and the Future of Farming meeting report.

Authors:

Monica Hoyos-Flight Emilie Brady Helen Sang Bruce Whitelaw

Transgenic Res 2017 04 31;26(2):319-321. Epub 2017 Jan 31.

The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush Campus, Midlothian, EH25 9RG, UK.

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April 2017

The development and maintenance of the mononuclear phagocyte system of the chick is controlled by signals from the macrophage colony-stimulating factor receptor.

Authors:

Valerie Garceau Adam Balic Carla Garcia-Morales Kristin A Sauter Mike J McGrew Jacqueline Smith Lonneke Vervelde Adrian Sherman Troy E Fuller Theodore Oliphant John A Shelley Raksha Tiwari Thomas L Wilson Cosmin Chintoan-Uta Dave W Burt Mark P Stevens Helen M Sang David A Hume

BMC Biol 2015 Feb 19;13:12. Epub 2015 Feb 19.

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February 2015

Myosin-II-mediated cell shape changes and cell intercalation contribute to primitive streak formation.

Authors:

Emil Rozbicki Manli Chuai Antti I Karjalainen Feifei Song Helen M Sang René Martin Hans-Joachim Knölker Michael P MacDonald Cornelis J Weijer

Nat Cell Biol 2015 Apr;17(4):397-408

Division of Cell and Developmental Biology, College of Life Sciences, University of Dundee, Dundee, DD1 5EH, Scotland, UK.

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April 2015

Cell-autonomous sex differences in gene expression in chicken bone marrow-derived macrophages.

Authors:

Carla Garcia-Morales Sunil Nandi Debiao Zhao Kristin A Sauter Lonneke Vervelde Derek McBride Helen M Sang Mike Clinton David A Hume

J Immunol 2015 Mar 30;194(5):2338-44. Epub 2015 Jan 30.

Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Midlothian EH25 9RG, Scotland, United Kingdom

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March 2015

Visualisation of chicken macrophages using transgenic reporter genes: insights into the development of the avian macrophage lineage.

Authors:

Adam Balic Carla Garcia-Morales Lonneke Vervelde Hazel Gilhooley Adrian Sherman Valerie Garceau Maria W Gutowska David W Burt Pete Kaiser David A Hume Helen M Sang

Development 2014 Aug 25;141(16):3255-65. Epub 2014 Jul 25.

The Roslin Institute and Royal (Dick) School of Veterinary Sciences, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK

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August 2014

A novel piggyBac transposon inducible expression system identifies a role for AKT signalling in primordial germ cell migration.

Authors:

James D Glover Lorna Taylor Adrian Sherman Caroline Zeiger-Poli Helen M Sang Michael J McGrew

PLoS One 2013 4;8(11):e77222. Epub 2013 Nov 4.

The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush Campus, Midlothian, United Kingdom.

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August 2014

Production and characterisation of a monoclonal antibody that recognises the chicken CSF1 receptor and confirms that expression is restricted to macrophage-lineage cells.

Authors:

Carla Garcia-Morales Lisa Rothwell Lindsey Moffat Valerie Garceau Adam Balic Helen M Sang Pete Kaiser David A Hume

Dev Comp Immunol 2014 Feb 29;42(2):278-85. Epub 2013 Sep 29.

The Roslin Institute & Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK.

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February 2014

Efficient genetic modification and germ-line transmission of primordial germ cells using piggyBac and Tol2 transposons.

Authors:

Joni Macdonald Lorna Taylor Adrian Sherman Koichi Kawakami Yoshiko Takahashi Helen M Sang Michael J McGrew

Proc Natl Acad Sci U S A 2012 Jun 14;109(23):E1466-72. Epub 2012 May 14.

Division of Developmental Biology, The Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh, Midlothian, EH25 9RG, United Kingdom.

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June 2012