Helen Morrison

Helen Morrison

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Helen Morrison

Helen Morrison

Publications by authors named "Helen Morrison"

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Neurofibromatosis type 2 and multiple sclerosis.

Mult Scler Relat Disord 2019 Dec 9;39:101890. Epub 2019 Dec 9.

Department of Neurosurgery, Helios Klinikum, Erfurt 99089, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.msard.2019.101890DOI Listing
December 2019

The NF2 tumor suppressor merlin interacts with Ras and RasGAP, which may modulate Ras signaling.

Oncogene 2019 09 16;38(36):6370-6381. Epub 2019 Jul 16.

Leibniz Institute on Aging, Fritz Lipmann Institute, Beutenbergstr. 11, 07745, Jena, Germany.

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http://dx.doi.org/10.1038/s41388-019-0883-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756068PMC
September 2019

Metabolic enzyme PDK3 forms a positive feedback loop with transcription factor HSF1 to drive chemoresistance.

Theranostics 2019 9;9(10):2999-3013. Epub 2019 May 9.

Laboratory of Cancer Biology, Key Lab of Biotherapy in Zhejiang, Sir Run Run Shaw Hospital, Medical School of Zhejiang University, Hangzhou, China.

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http://www.thno.org/v09p2999.htm
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http://dx.doi.org/10.7150/thno.31301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568185PMC
May 2019

Construction of cloning-friendly minigenes for mammalian expression of full-length human NF1 isoforms.

Hum Mutat 2019 02 24;40(2):187-192. Epub 2018 Nov 24.

Leibniz Institute on Aging, Fritz Lipmann Institute (FLI), Jena, Germany.

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http://doi.wiley.com/10.1002/humu.23681
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http://dx.doi.org/10.1002/humu.23681DOI Listing
February 2019

Heat Shock Factor 1 Epigenetically Stimulates Glutaminase-1-Dependent mTOR Activation to Promote Colorectal Carcinogenesis.

Mol Ther 2018 07 14;26(7):1828-1839. Epub 2018 Apr 14.

Laboratory of Cancer Biology, Key Lab of Zhejiang Biotherapy, Sir Run Run Shaw Hospital, Medical School of Zhejiang University, Hangzhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2018.04.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035735PMC
July 2018

Neuropathies in the setting of Neurofibromatosis tumor syndromes: Complexities and opportunities.

Exp Neurol 2018 01 3;299(Pt B):334-344. Epub 2017 Jun 3.

Department of Neurology, University Medical Center Hamburg-Eppendorf, University of Hamburg, 20246 Hamburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.expneurol.2017.06.006DOI Listing
January 2018

Vitamin A regulates Akt signaling through the phospholipid fatty acid composition.

FASEB J 2017 10 7;31(10):4566-4577. Epub 2017 Jul 7.

Institute of Pharmacy, Friedrich-Schiller-University, Jena, Germany;

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http://dx.doi.org/10.1096/fj.201700078RDOI Listing
October 2017

Multifocal nerve lesions and LZTR1 germline mutations in segmental schwannomatosis.

Ann Neurol 2016 10 13;80(4):625-8. Epub 2016 Aug 13.

Department of Neuroradiology, Heidelberg University Hospital, Heidelberg, Germany.

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http://dx.doi.org/10.1002/ana.24753DOI Listing
October 2016

The importance of nerve microenvironment for schwannoma development.

Acta Neuropathol 2016 08 28;132(2):289-307. Epub 2016 May 28.

Leibniz Institute on Aging, Fritz Lipmann Institute, Beutenbergstrasse 11, 07745, Jena, Germany.

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http://dx.doi.org/10.1007/s00401-016-1583-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947119PMC
August 2016

Tumor Suppressor NF2 Blocks Cellular Migration by Inhibiting Ectodomain Cleavage of CD44.

Mol Cancer Res 2015 May 4;13(5):879-90. Epub 2015 Feb 4.

Leibniz Institute for Age Research, Fritz Lipmann Institute, Jena, Germany.

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http://dx.doi.org/10.1158/1541-7786.MCR-15-0020-TDOI Listing
May 2015

Deficiency of the protein-tyrosine phosphatase DEP-1/PTPRJ promotes matrix metalloproteinase-9 expression in meningioma cells.

J Neurooncol 2015 May 12;122(3):451-9. Epub 2015 Feb 12.

Institute of Molecular Cell Biology, CMB, Jena University Hospital, Hans-Knöll-Strasse 2, 07745, Jena, Germany.

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http://dx.doi.org/10.1007/s11060-015-1740-2DOI Listing
May 2015

Merlin's wizardry guides cohesive migration.

Nat Cell Biol 2015 Mar;17(3):212-3

Leibniz Institute for Age Research, Fritz Lipmann Institute, 07745 Jena, Germany.

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http://dx.doi.org/10.1038/ncb3126DOI Listing
March 2015

Novel mechanism of JNK pathway activation by adenoviral E1A.

Oncotarget 2014 Apr;5(8):2176-86

Leibniz Institute for Age Research - Fritz Lipmann Institute (FLI), Beutenbergstr. 11, D-07745 Jena, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039154PMC
http://dx.doi.org/10.18632/oncotarget.1860DOI Listing
April 2014

In vivo electrophysiological measurements on mouse sciatic nerves.

J Vis Exp 2014 Apr 13(86). Epub 2014 Apr 13.

Institute of Molecular Cell Biology & Center for Sepsis Control and Care (CSCC) Jena University Hospital, Friedrich Schiller University Jena;

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http://dx.doi.org/10.3791/51181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166965PMC
April 2014

Regulation of Son of sevenless by the membrane-actin linker protein ezrin.

Proc Natl Acad Sci U S A 2013 Dec 2;110(51):20587-92. Epub 2013 Dec 2.

H.M. Laboratory, P.H. Laboratory, and M.E.T. Laboratory, Leibniz Institute for Age Research - Fritz Lipmann Institute, 07745 Jena, Germany.

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http://dx.doi.org/10.1073/pnas.1222078110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870676PMC
December 2013

Activation of Ras requires the ERM-dependent link of actin to the plasma membrane.

PLoS One 2011 21;6(11):e27511. Epub 2011 Nov 21.

Morrison Laboratory, Leibniz Institute for Age Research-Fritz Lipmann Institute, Jena, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0027511PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221661PMC
April 2012

Merlin inhibits neurite outgrowth in the CNS.

J Neurosci 2010 Jul;30(30):10177-86

Institute of Age Research, Fritz Lipmann Institute, Beutenbergstrasse 11, Jena, Germany.

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http://dx.doi.org/10.1523/JNEUROSCI.0840-10.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6633373PMC
July 2010

Properties of an ezrin mutant defective in F-actin binding.

J Mol Biol 2009 Jan 3;385(4):1015-31. Epub 2008 Dec 3.

Leibniz Institute of Age Research, Fritz Lipmann Institute, Beutenbergstrasse 11, 07745 Jena, Germany.

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http://dx.doi.org/10.1016/j.jmb.2008.11.051DOI Listing
January 2009

Hepatocyte growth factor-induced Ras activation requires ERM proteins linked to both CD44v6 and F-actin.

Mol Biol Cell 2007 Jan 25;18(1):76-83. Epub 2006 Oct 25.

Forschungszentrum Karlsruhe, Institute of Toxicology and Genetics, 76021 Karlsruhe, Germany.

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http://dx.doi.org/10.1091/mbc.e06-08-0674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1751326PMC
January 2007

Merlin/neurofibromatosis type 2 suppresses growth by inhibiting the activation of Ras and Rac.

Cancer Res 2007 Jan;67(2):520-7

Institute of Age Research, Fritz-Lipmann-Institute, Jena, Germany.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-1608DOI Listing
January 2007

Tumorigenic transformation by CPI-17 through inhibition of a merlin phosphatase.

Nature 2006 Aug;442(7102):576-9

Leibniz Institute of Age Research-Fritz-Lipmann-Institute, Beutenbergstrasse 11, 07745 Jena, Germany.

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http://dx.doi.org/10.1038/nature04856DOI Listing
August 2006

Listeria monocytogenes exploits ERM protein functions to efficiently spread from cell to cell.

EMBO J 2005 Mar 24;24(6):1287-300. Epub 2005 Feb 24.

Department of Cell Biology, Gesellschaft für Biotechnologische Forschung (GBF), Braunschweig, Germany.

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http://dx.doi.org/10.1038/sj.emboj.7600595DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC556399PMC
March 2005

Neurofibromatosis 2 (NF2) tumor suppressor schwannomin and its interacting protein HRS regulate STAT signaling.

Hum Mol Genet 2002 Dec;11(25):3179-89

Cedars-Sinai Medical Center, School of Medicine, University of California at Los Angeles, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA.

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http://dx.doi.org/10.1093/hmg/11.25.3179DOI Listing
December 2002

Neurofibromatosis 2 (NF2) tumor suppressor schwannomin and its interacting protein HRS regulate STAT signaling.

Hum Mol Genet 2002 Dec;11(25):3179-89

Cedars-Sinai Medical Center, School of Medicine, University of California at Los Angeles, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA.

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http://dx.doi.org/10.1093/hmg/11.25.3179DOI Listing
December 2002