Helen M Colhoun

Helen M Colhoun

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Helen M Colhoun

Publications by authors named "Helen M Colhoun"

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Biomarker panels associated with progression of renal disease in type 1 diabetes.

Diabetologia 2019 Sep 20;62(9):1616-1627. Epub 2019 Jun 20.

MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Crewe Road South, Edinburgh, EH4 2XU, UK.

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http://dx.doi.org/10.1007/s00125-019-4915-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677704PMC
September 2019

Factors associated with stillbirth in women with diabetes.

Diabetologia 2019 Jul 29. Epub 2019 Jul 29.

Institute of Cardiovascular and Medical Sciences, British Heart Foundation Glasgow Cardiovascular Research Centre, University of Glasgow, 126 University Place, Glasgow, G12 8TA, UK.

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http://dx.doi.org/10.1007/s00125-019-4943-9DOI Listing
July 2019

Pharmacoepidemiology: Using randomised control trials and observational studies in clinical decision-making.

Br J Clin Pharmacol 2019 Jun 17. Epub 2019 Jun 17.

Queen's Medical Research Institute, University of Edinburgh, UK.

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http://dx.doi.org/10.1111/bcp.14024DOI Listing
June 2019

Trends in incidence and case fatality of acute myocardial infarction, angina and coronary revascularisation in people with and without type 2 diabetes in Scotland between 2006 and 2015.

Diabetologia 2019 03 17;62(3):418-425. Epub 2019 Jan 17.

Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, UK.

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http://dx.doi.org/10.1007/s00125-018-4796-7DOI Listing
March 2019

Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control.

Diabetes 2019 02 28;68(2):441-456. Epub 2018 Nov 28.

Massachusetts Eye and Ear Department of Ophthalmology, Harvard Medical School, Boston, MA

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http://dx.doi.org/10.2337/db18-0567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341299PMC
February 2019

Body Weight Variability and Cardiovascular Outcomes in Patients With Type 2 Diabetes Mellitus.

Circ Cardiovasc Qual Outcomes 2018 11;11(11):e004724

Department of Cardiology, Zuckerberg San Francisco General Hospital, CA (D.D.W.).

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http://dx.doi.org/10.1161/CIRCOUTCOMES.118.004724DOI Listing
November 2018

Baseline and on-statin treatment lipoprotein(a) levels for prediction of cardiovascular events: individual patient-data meta-analysis of statin outcome trials.

Lancet 2018 10 4;392(10155):1311-1320. Epub 2018 Oct 4.

Vascular Medicine Program, Sulpizio Cardiovascular Center, Division of Cardiology, Department of Medicine, University of California San Diego, La Jolla, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(18)31652-0DOI Listing
October 2018

A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes.

Diabetes 2018 07 27;67(7):1414-1427. Epub 2018 Apr 27.

Wellcome Centre Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K.

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http://dx.doi.org/10.2337/db17-0914DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014557PMC
July 2018

Efficacy and safety of lipid lowering by alirocumab in chronic kidney disease.

Kidney Int 2018 06 8;93(6):1397-1408. Epub 2018 Mar 8.

Department of Hypertension, Medical University of Lodz, Lodz, Poland.

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http://dx.doi.org/10.1016/j.kint.2017.12.011DOI Listing
June 2018

Diabetes and pregnancy: national trends over a 15 year period.

Diabetologia 2018 05 11;61(5):1081-1088. Epub 2018 Jan 11.

Institute of Cardiovascular and Medical Sciences, British Heart Foundation Glasgow Cardiovascular Research Centre, University of Glasgow, 126 University Place, Glasgow, G12 8TA, UK.

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http://dx.doi.org/10.1007/s00125-017-4529-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448996PMC
May 2018

Biomarkers of diabetic kidney disease.

Diabetologia 2018 05 8;61(5):996-1011. Epub 2018 Mar 8.

Department of Paediatrics, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1007/s00125-018-4567-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448994PMC
May 2018

Development and Validation of a Path Length Calculation for Carotid-Femoral Pulse Wave Velocity Measurement: A TASCFORCE, SUMMIT, and Caerphilly Collaborative Venture.

Hypertension 2018 05 19;71(5):937-945. Epub 2018 Mar 19.

From the Division of Molecular and Clinical Medicine, College of Medicine, University of Dundee, United Kingdom (J.R.W.-M., L.B., J.S., F.K., A.D.S., J.G.H.); NHS Tayside Clinical Radiology, Ninewells Hospital, Dundee, United Kingdom (P.T., M.B.-M., S.C.C.); Department of Research and Innovation, North York General Hospital, University of Toronto, Canada (F.S.); Centre for Genomic and Experimental Medicine, The University of Edinburgh, Western General Hospital, United Kingdom (H.M.C.); NIHR Exeter Clinical Research Facility, Royal Devon and Exeter Hospital and University of Exeter Medical School, United Kingdom (A.C.S., K.A.); Lund University Diabetes Centre, Lund University, Malmö, Sweden (L.G.); Department of Clinical Sciences Malmö, Lund University, Sweden (J.N.); Department of Cardiology, Wales Heart Research Institute, Cardiff, United Kingdom (J.R.C.); Division of Experimental Medicine & Immunotherapeutics, University of Cambridge, United Kingdom (C.M.M., I.B.W.); and Population Health Sciences, University of Bristol, United Kingdom (Y.B.-S.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.117.10620DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902134PMC
May 2018

Epicardial adipose tissue is related to arterial stiffness and inflammation in patients with cardiovascular disease and type 2 diabetes.

BMC Cardiovasc Disord 2018 02 13;18(1):31. Epub 2018 Feb 13.

Division of Molecular and Clinical Medicine, University of Dundee, Mailbox 2, Ninewells Hospital & Medical School, Dundee, DD1 9SY, UK.

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http://dx.doi.org/10.1186/s12872-018-0770-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809843PMC
February 2018

Automated pathway and reaction prediction facilitates in silico identification of unknown metabolites in human cohort studies.

J Chromatogr B Analyt Technol Biomed Life Sci 2017 Dec 4;1071:58-67. Epub 2017 Apr 4.

Institute of Bioinformatics and Systems Biology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jchromb.2017.04.002DOI Listing
December 2017

Efficacy and safety of alirocumab in insulin-treated individuals with type 1 or type 2 diabetes and high cardiovascular risk: The ODYSSEY DM-INSULIN randomized trial.

Diabetes Obes Metab 2017 12 10;19(12):1781-1792. Epub 2017 Oct 10.

University of California San Diego School of Medicine, and Center for Metabolic Research, Veterans Affairs, San Diego Healthcare System, San Diego, California.

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http://dx.doi.org/10.1111/dom.13114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698740PMC
December 2017

Modelling cumulative exposure for inference about drug effects in observational studies.

Pharmacoepidemiol Drug Saf 2017 Dec 12;26(12):1527-1533. Epub 2017 Oct 12.

Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.

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http://doi.wiley.com/10.1002/pds.4327
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http://dx.doi.org/10.1002/pds.4327DOI Listing
December 2017

Antidrug Antibodies in Patients Treated with Alirocumab.

N Engl J Med 2017 04 17;376(16):1589-90. Epub 2017 Mar 17.

University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1056/NEJMc1616623DOI Listing
April 2017

Meta-analysis of genome-wide association studies of HDL cholesterol response to statins.

J Med Genet 2016 12 1;53(12):835-845. Epub 2016 Sep 1.

Department of Atherosclerosis Research, Children's Hospital Oakland Research Institute, Oakland, California, USA.

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http://dx.doi.org/10.1136/jmedgenet-2016-103966DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309131PMC
December 2016

Erratum to: Trends in type 2 diabetes incidence and mortality in Scotland between 2004 and 2013.

Diabetologia 2016 11;59(11):2492

Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, UK.

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http://dx.doi.org/10.1007/s00125-016-4089-yDOI Listing
November 2016

Trends in type 2 diabetes incidence and mortality in Scotland between 2004 and 2013.

Diabetologia 2016 10 28;59(10):2106-13. Epub 2016 Jul 28.

Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, UK.

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http://dx.doi.org/10.1007/s00125-016-4054-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016553PMC
October 2016

Development and Validation of a Model to Predict Absolute Vascular Risk Reduction by Moderate-Intensity Statin Therapy in Individual Patients With Type 2 Diabetes Mellitus: The Anglo Scandinavian Cardiac Outcomes Trial, Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial, and Collaborative Atorvastatin Diabetes Study.

Circ Cardiovasc Qual Outcomes 2016 05 11;9(3):213-21. Epub 2016 May 11.

From the Department of Vascular Medicine (L.K., F.L.J.V.) and Julius Centre for Health Sciences and Primary Care (Y.v.d.G.), University Medical Centre Utrecht, Utrecht, The Netherlands; ICCH, Imperial College London, London, United Kingdom (N.R.P., P.S.S.); Biomedical Research Institute, University of Dundee, Dundee, Scotland, United Kingdom (H.M.C., S.J.L.); Department of Cardiology, Academic Medical Centre, Amsterdam, The Netherlands (S.M.B.); and University of Texas Health Science Center, Houston (S.L.P., B.R.D.).

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http://dx.doi.org/10.1161/CIRCOUTCOMES.115.001980DOI Listing
May 2016

A Genome-Wide Association Study Provides New Evidence That CACNA1C Gene is Associated With Diabetic Cataract.

Invest Ophthalmol Vis Sci 2016 Apr;57(4):2246-50

Division of Population Health Sciences Ninewells Hospital and School of Medicine, University of Dundee, Dundee, United Kingdom.

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http://dx.doi.org/10.1167/iovs.16-19332DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855826PMC
April 2016

Effect of atorvastatin on glycaemia progression in patients with diabetes: an analysis from the Collaborative Atorvastatin in Diabetes Trial (CARDS).

Diabetologia 2016 Feb 17;59(2):299-306. Epub 2015 Nov 17.

Diabetes Epidemiology Unit, Division of Population Health Sciences, University of Dundee, The Mackenzie Building, Kirsty Semple Way, Dundee, DD2 4BF, Scotland, UK.

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http://dx.doi.org/10.1007/s00125-015-3802-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705133PMC
February 2016

A Genome-wide Association Study Provides Evidence of Sex-specific Involvement of Chr1p35.1 (ZSCAN20-TLR12P) and Chr8p23.1 (HMGB1P46) With Diabetic Neuropathic Pain.

EBioMedicine 2015 Oct 4;2(10):1386-93. Epub 2015 Aug 4.

Division of Population Health Sciences, Medical Research Institute, Ninewells Hospital and School of Medicine, University of Dundee, Dundee DD2 4BF, UK.

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http://dx.doi.org/10.1016/j.ebiom.2015.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634194PMC
October 2015

Cohort comparison study of cardiac disease and atherosclerotic burden in type 2 diabetic adults using whole body cardiovascular magnetic resonance imaging.

Cardiovasc Diabetol 2015 Sep 18;14:122. Epub 2015 Sep 18.

Division of Cardiovascular and Diabetes Medicine, Medical Research Institute, University of Dundee, Level 7, Ninewells Hospital, Dundee, DD1 9SY, UK.

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http://dx.doi.org/10.1186/s12933-015-0284-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574534PMC
September 2015

Elevated Plasma Levels of MMP-12 Are Associated With Atherosclerotic Burden and Symptomatic Cardiovascular Disease in Subjects With Type 2 Diabetes.

Arterioscler Thromb Vasc Biol 2015 Jul 7;35(7):1723-31. Epub 2015 May 7.

From the Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden (I.G., E.B., A.E., P.D., G.N.F., H.B., G.Ö., M.P., J.N.); Medical Research Institute, University of Dundee, Dundee, UK (H.M.C., F.K., H.C.L., F.A., J.B.); Institute of Biomedical and Clinical Science, Diabetes and Vascular Medicine, NIHR Exeter Clinical Research Facility and University of Exeter Medical School, Exeter, UK (A.C.S., K.A., F.C., K.G., D.S.); Department of Clinical and Experimental Medicine (A.N., S.P., E.V.) and Department of Surgical, Medical, Molecular and Critical Area Pathology (C.P., M.K.), University of Pisa, Pisa, Italy; and AstraZeneca, Cardiovascular and Metabolic Diseases, Mölndal, Sweden (L.-M.G., V.S.).

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http://dx.doi.org/10.1161/ATVBAHA.115.305631DOI Listing
July 2015

Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins.

Authors:
Iris Postmus Stella Trompet Harshal A Deshmukh Michael R Barnes Xiaohui Li Helen R Warren Daniel I Chasman Kaixin Zhou Benoit J Arsenault Louise A Donnelly Kerri L Wiggins Christy L Avery Paula Griffin QiPing Feng Kent D Taylor Guo Li Daniel S Evans Albert V Smith Catherine E de Keyser Andrew D Johnson Anton J M de Craen David J Stott Brendan M Buckley Ian Ford Rudi G J Westendorp P Eline Slagboom Naveed Sattar Patricia B Munroe Peter Sever Neil Poulter Alice Stanton Denis C Shields Eoin O'Brien Sue Shaw-Hawkins Y-D Ida Chen Deborah A Nickerson Joshua D Smith Marie Pierre Dubé S Matthijs Boekholdt G Kees Hovingh John J P Kastelein Paul M McKeigue John Betteridge Andrew Neil Paul N Durrington Alex Doney Fiona Carr Andrew Morris Mark I McCarthy Leif Groop Emma Ahlqvist Joshua C Bis Kenneth Rice Nicholas L Smith Thomas Lumley Eric A Whitsel Til Stürmer Eric Boerwinkle Julius S Ngwa Christopher J O'Donnell Ramachandran S Vasan Wei-Qi Wei Russell A Wilke Ching-Ti Liu Fangui Sun Xiuqing Guo Susan R Heckbert Wendy Post Nona Sotoodehnia Alice M Arnold Jeanette M Stafford Jingzhong Ding David M Herrington Stephen B Kritchevsky Gudny Eiriksdottir Leonore J Launer Tamara B Harris Audrey Y Chu Franco Giulianini Jean G MacFadyen Bryan J Barratt Fredrik Nyberg Bruno H Stricker André G Uitterlinden Albert Hofman Fernando Rivadeneira Valur Emilsson Oscar H Franco Paul M Ridker Vilmundur Gudnason Yongmei Liu Joshua C Denny Christie M Ballantyne Jerome I Rotter L Adrienne Cupples Bruce M Psaty Colin N A Palmer Jean-Claude Tardif Helen M Colhoun Graham Hitman Ronald M Krauss J Wouter Jukema Mark J Caulfield

Nat Commun 2014 Oct 28;5:5068. Epub 2014 Oct 28.

1] NIHR Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London EC1M 6BQ, UK [2] Department of Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine, Queen Mary University of London, London EC1M6BQ, UK.

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http://dx.doi.org/10.1038/ncomms6068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220464PMC
October 2014

Levels and changes of HDL cholesterol and apolipoprotein A-I in relation to risk of cardiovascular events among statin-treated patients: a meta-analysis.

Circulation 2013 Oct 21;128(14):1504-12. Epub 2013 Aug 21.

Departments of Cardiology (S.M.B.) and Vascular Medicine (B.J.A., G.K.H., J.J.P.K.), Academic Medical Center, Amsterdam, The Netherlands; Center for Cardiovascular Disease Prevention, Brigham and Women's Hospital, Boston, MA (S.M., P.M.R.); Center of Preventive Medicine, Oslo University Hospital, Ulleval and University of Oslo, Norway (T.R.P.); State University of New York Health Science Center, Brooklyn, NY (J.C.L.); Rosalind Franklin University of Medicine and Science, North Chicago, IL (K.M.A.W.); Department of Neurology and Stroke Center, Bichat University Hospital, Paris, France (P.A.); Global Pharmaceuticals Pfizer, New York, NY (D.A.D.); Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia (A.M.T.); Department of Biochemistry and Lipid Clinic, Royal Prince Alfred Hospital, University of Sydney, Sydney, Australia (D.R.S.); NHMRC Clinical Trials Centre, University of Sydney, Sydney, Australia (A.K.); Medical Research Institute, University of Dundee, Dundee, United Kingdom (H.M.C.); Centre for Diabetes, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom (G.A.H.); Department of Medicine, Royal Free and University College Medical School, London, United Kingdom (D.J.B.); School of Biomedicine, University of Manchester, Manchester, United Kingdom (P.N.D.); Touro University, Mare Island, CA (M.B.C.); Department of Medicine, University of Texas Health Science Center, and VERDICT, South Texas Veterans Health Care System, San Antonio, TX (J.R.D.); and Weill Cornell Medical College, New York, NY (A.M.G.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.002670DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807966PMC
October 2013

Plasma levels of advanced glycation endproducts are associated with type 1 diabetes and coronary artery calcification.

Cardiovasc Diabetol 2013 Oct 17;12:149. Epub 2013 Oct 17.

Department of Internal Medicine, Maastricht University Medical Centre (MUMC) and Cardiovascular Research Institute Maastricht (CARIM), Universiteitssingel 50, Maastricht 6200, MD, the Netherlands.

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http://dx.doi.org/10.1186/1475-2840-12-149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015708PMC
October 2013

New susceptibility loci associated with kidney disease in type 1 diabetes.

PLoS Genet 2012 Sep 20;8(9):e1002921. Epub 2012 Sep 20.

Folkhälsan Institute of Genetics, Folkhälsan Research Center, Biomedicum Helsinki, Helsinki, Finland.

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http://pure.qub.ac.uk/portal/files/2407268/New_Susceptibilit
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http://dx.plos.org/10.1371/journal.pgen.1002921
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http://dx.doi.org/10.1371/journal.pgen.1002921DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447939PMC
September 2012

The safety and tolerability of atorvastatin 10 mg in the Collaborative Atorvastatin Diabetes Study (CARDS).

Diab Vasc Dis Res 2008 Sep;5(3):177-83

Department of Medicine, New York University School of Medicine, VA Hospital, 423 East 23rd Street, Dept of Medicine -11093 South, New York, NY 10010, USA.

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http://dx.doi.org/10.3132/dvdr.2008.029DOI Listing
September 2008

Lipid goals in metabolic syndrome and diabetes.

Authors:
Helen M Colhoun

Curr Atheroscler Rep 2007 Oct;9(4):286-95

The Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland.

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October 2007

Eicosapentaenoic acid for prevention of major coronary events.

Authors:
Helen M Colhoun

Lancet 2007 Jul;370(9583):215

The Conway Institute, Dublin 4, Ireland. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(07)61112-XDOI Listing
July 2007

Analysis of efficacy and safety in patients aged 65-75 years at randomization: Collaborative Atorvastatin Diabetes Study (CARDS).

Diabetes Care 2006 Nov;29(11):2378-84

Division of Public Health and Primary Health Care, University of Oxford, Old Road Campus, Headington, Oxford OX3 7LF, UK.

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http://care.diabetesjournals.org/cgi/doi/10.2337/dc06-0872
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http://dx.doi.org/10.2337/dc06-0872DOI Listing
November 2006

High risk of cardiovascular disease in patients with type 1 diabetes in the U.K.: a cohort study using the general practice research database.

Diabetes Care 2006 Apr;29(4):798-804

Department of Epidemiology and Public Health, Royal Free and University College London Medical School, UK.

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http://dx.doi.org/10.2337/diacare.29.04.06.dc05-1433DOI Listing
April 2006

Treatment of lipid disorders in patients with diabetes.

Curr Treat Options Cardiovasc Med 2006 Feb;8(1):37-45

The Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland.

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February 2006

Human cytomegalovirus seropositivity is associated with impaired vascular function.

Circulation 2003 Aug 4;108(6):678-83. Epub 2003 Aug 4.

Department of Epidemiology and Public Health, University College London, 5 University St, London, WC1E 6JJ, UK.

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https://www.ahajournals.org/doi/10.1161/01.CIR.0000084505.54
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http://dx.doi.org/10.1161/01.CIR.0000084505.54603.C7DOI Listing
August 2003

Problems of reporting genetic associations with complex outcomes.

Lancet 2003 Mar;361(9360):865-72

Department of Epidemiology and Public Health, University College London, WC1E 6BT, London, UK.

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http://dx.doi.org/10.1016/s0140-6736(03)12715-8DOI Listing
March 2003

C-reactive protein in type 1 diabetes and its relationship to coronary artery calcification.

Diabetes Care 2002 Oct;25(10):1813-7

Department of Epidemiology and Public Health, Royal Free and University College London Medical School, London, UK.

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http://dx.doi.org/10.2337/diacare.25.10.1813DOI Listing
October 2002