Publications by authors named "Helen E Heslop"

99Publications

Engineered off-the-shelf therapeutic T cells resist host immune rejection.

Nat Biotechnol 2020 Jul 13. Epub 2020 Jul 13.

Center for Cell and Gene Therapy, Baylor College of Medicine, Texas Children's Hospital and Houston Methodist Hospital, Houston, TX, USA.

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http://dx.doi.org/10.1038/s41587-020-0601-5DOI Listing
July 2020

Sensitizing Burkitt lymphoma to EBV-CTLs.

Authors:
Helen E Heslop

Blood 2020 May;135(21):1822-1823

Baylor College of Medicine.

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http://dx.doi.org/10.1182/blood.2020005492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243150PMC
May 2020

CRISPR-Edited Immune Effectors: The End of the Beginning.

Mol Ther 2020 04 22;28(4):995-996. Epub 2020 Mar 22.

Center for Cell and Gene Therapy, Baylor College of Medicine, Houston Methodist Hospital and Texas Children's Hospital, Houston, TX, USA; Graduate Program in Translational Biology and Molecular Medicine, Baylor College of Medicine, Houston, TX, USA.

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http://dx.doi.org/10.1016/j.ymthe.2020.03.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132620PMC
April 2020

Incorporation of thiotepa in a reduced intensity conditioning regimen may improve engraftment after transplant for HLH.

Br J Haematol 2020 03 27;188(6):e84-e87. Epub 2020 Jan 27.

Center for Cell and Gene Therapy, Texas Children's Hospital, Baylor College of Medicine, Houston Methodist Hospital, Houston, TX, USA.

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http://dx.doi.org/10.1111/bjh.16370DOI Listing
March 2020

CAR-T cell Therapy for Non-Hodgkin Lymphomas: A New Treatment Paradigm.

Adv Cell Gene Ther 2019 Jul 28;2(3). Epub 2019 Mar 28.

The Center for Cell and Gene Therapy, Baylor College of Medicine, Houston Methodist Hospital and Texas Children's Hospital, Houston, Texas.

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http://dx.doi.org/10.1002/acg2.54DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880960PMC
July 2019

Epigenetic Inhibition Puts Target Antigen in the Crosshairs of CAR T Cells.

Mol Ther 2019 05 18;27(5):900-901. Epub 2019 Apr 18.

Center for Cell and Gene Therapy, Baylor College of Medicine, Houston Methodist Hospital and Texas Children's Hospital, Houston, TX, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15250016193017
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http://dx.doi.org/10.1016/j.ymthe.2019.04.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520459PMC
May 2019

Adoptive Immunotherapy with Antigen-Specific T Cells Expressing a Native TCR.

Cancer Immunol Res 2019 04;7(4):528-533

Center for Cell and Gene Therapy, Baylor College of Medicine, Houston Methodist Hospital and Texas Children's Hospital, Houston, Texas.

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http://dx.doi.org/10.1158/2326-6066.CIR-18-0888DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462216PMC
April 2019

Harmonizing Immune Effector Toxicity Reporting.

Biol Blood Marrow Transplant 2019 04 5;25(4):e121-e122. Epub 2019 Jan 5.

Department of Stem Cell Transplant and Cellular Therapy, University of Texas M.D. Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1016/j.bbmt.2019.01.001DOI Listing
April 2019

In Vivo Fate and Activity of Second- versus Third-Generation CD19-Specific CAR-T Cells in B Cell Non-Hodgkin's Lymphomas.

Mol Ther 2018 12 13;26(12):2727-2737. Epub 2018 Sep 13.

Center for Cell and Gene Therapy, Baylor College of Medicine, Houston Methodist Hospital and Texas Children's Hospital, Houston, TX 77030, USA; Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2018.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277484PMC
December 2018

Generation of multivirus-specific T cells by a single stimulation of peripheral blood mononuclear cells with a peptide mixture using serum-free medium.

Cytotherapy 2018 09 17;20(9):1182-1190. Epub 2018 Aug 17.

Division of Molecular Therapy, Advanced Clinical Research Center, The Institute of Medical Science, University of Tokyo, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jcyt.2018.05.009DOI Listing
September 2018

A backpack revs up T-cell activity.

Nat Biotechnol 2018 08;36(8):702-703

Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, Texas, USA.

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http://dx.doi.org/10.1038/nbt.4215DOI Listing
August 2018

The use of chimeric antigen receptor T cells in patients with non-Hodgkin lymphoma.

Clin Adv Hematol Oncol 2018 May;16(5):375-386

Baylor College of Medicine, Houston, Texas.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469642PMC
May 2018

Current Allogeneic Hematopoietic Stem Cell Transplantation for Pediatric Acute Lymphocytic Leukemia: Success, Failure and Future Perspectives-A Single-Center Experience, 2008 to 2016.

Biol Blood Marrow Transplant 2018 07 14;24(7):1424-1431. Epub 2018 Mar 14.

Center for Cell and Gene Therapy, Baylor College of Medicine, Texas Children's Hospital, Houston Methodist Hospital. Houston, Texas.

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http://dx.doi.org/10.1016/j.bbmt.2018.03.001DOI Listing
July 2018

Tumor-Specific T-Cells Engineered to Overcome Tumor Immune Evasion Induce Clinical Responses in Patients With Relapsed Hodgkin Lymphoma.

J Clin Oncol 2018 04 9;36(11):1128-1139. Epub 2018 Jan 9.

Catherine M. Bollard, Tamara Tripic, Gianpietro Dotti, Stephen Gottschalk, Vicky Torrano, Olga Dakhova, George Carrum, Carlos A. Ramos, Adrian P. Gee, Malcolm K. Brenner, Helen E. Heslop, and Cliona M. Rooney, Houston Methodist Hospital, and Texas Children's Hospital; Catherine M. Bollard, Gianpietro Dotti, Stephen Gottschalk, George Carrum, Carlos A. Ramos, Hao Liu, Meng-Fen Wu, Andrea N. Marcogliese, Adrian P. Gee, Malcolm K. Brenner, Helen E. Heslop, and Cliona M. Rooney, Baylor College of Medicine, Houston, TX; Catherine M. Bollard, Conrad Russell Cruz, and Cecilia Barese, Children's National Health System, Washington, DC; Youli Zu and Daniel Y. Lee, Weill Medical College of Cornell University; and Owen O'Connor, Columbia University College of Physicians and Surgeons, The New York Presbyterian Hospital, New York, NY.

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http://ascopubs.org/doi/10.1200/JCO.2017.74.3179
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http://dx.doi.org/10.1200/JCO.2017.74.3179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891126PMC
April 2018

Seek and You Will Not Find: Ending the Hunt for Replication-Competent Retroviruses during Human Gene Therapy.

Mol Ther 2018 01 20;26(1):1-2. Epub 2017 Dec 20.

Center for Cell and Gene Therapy, Baylor College of Medicine, Houston Methodist Hospital and Texas Children's Hospital, Houston, TX, USA.

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http://dx.doi.org/10.1016/j.ymthe.2017.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763151PMC
January 2018

Clinical and immunological responses after CD30-specific chimeric antigen receptor-redirected lymphocytes.

J Clin Invest 2017 Sep 14;127(9):3462-3471. Epub 2017 Aug 14.

Center for Cell and Gene Therapy, Baylor College of Medicine, Houston Methodist Hospital and Texas Children's Hospital, Houston, Texas, USA.

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http://dx.doi.org/10.1172/JCI94306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669573PMC
September 2017

Off-the-Shelf Virus-Specific T Cells to Treat BK Virus, Human Herpesvirus 6, Cytomegalovirus, Epstein-Barr Virus, and Adenovirus Infections After Allogeneic Hematopoietic Stem-Cell Transplantation.

J Clin Oncol 2017 Nov 7;35(31):3547-3557. Epub 2017 Aug 7.

Ifigeneia Tzannou, Anastasia Papadopoulou, Swati Naik, Kathryn Leung, Caridad A. Martinez, Carlos A. Ramos, George Carrum, Ghadir Sasa, Premal Lulla, Ayumi Watanabe, Manik Kuvalekar, Adrian P. Gee, Bambi J. Grilley, Robert A. Krance, Stephen Gottschalk, Malcolm K. Brenner, Cliona M. Rooney, Helen E. Heslop, Ann M. Leen, and Bilal Omer, Center for Cell and Gene Therapy, Baylor College of Medicine, Texas Children's Hospital, and Houston Methodist Hospital; Meng-Fen Wu and Hao Liu, Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX.

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http://dx.doi.org/10.1200/JCO.2017.73.0655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662844PMC
November 2017

Equal opportunity CAR T cells.

Blood 2017 06;129(25):3275-3277

BAYLOR COLLEGE OF MEDICINE; HOUSTON METHODIST HOSPITAL; TEXAS CHILDREN'S HOSPITAL.

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http://dx.doi.org/10.1182/blood-2017-04-779983DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482104PMC
June 2017

Fine-tuning the CAR spacer improves T-cell potency.

Oncoimmunology 2016 8;5(12):e1253656. Epub 2016 Nov 8.

Center for Cell and Gene Therapy, Baylor College of Medicine, Texas Children's Hospital, and Houston Methodist Hospital , Houston, Texas, USA.

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http://dx.doi.org/10.1080/2162402X.2016.1253656DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214260PMC
November 2016

Exhausting alloreactivity of donor-derived CAR T cells.

Nat Med 2017 02;23(2):147-148

Center for Cell and Gene Therapy, Baylor College of Medicine, Houston Methodist Hospital and Texas Children's Hospital, Houston, Texas, USA.

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http://dx.doi.org/10.1038/nm.4276DOI Listing
February 2017

Fall of the mutants: T cells targeting BCR-ABL.

Blood 2017 02;129(5):539-540

BAYLOR COLLEGE OF MEDICINE.

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http://dx.doi.org/10.1182/blood-2016-12-757336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290991PMC
February 2017

Improving Chimeric Antigen Receptor-Modified T Cell Function by Reversing the Immunosuppressive Tumor Microenvironment of Pancreatic Cancer.

Mol Ther 2017 01 4;25(1):249-258. Epub 2017 Jan 4.

Center for Cell and Gene Therapy, Baylor College of Medicine, Texas Children's Hospital, and Houston Methodist Hospital, Houston, TX 77030, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15250016164537
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http://dx.doi.org/10.1016/j.ymthe.2016.10.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363304PMC
January 2017

Checkpoint inhibition and cellular immunotherapy in lymphoma.

Hematology Am Soc Hematol Educ Program 2016 Dec;2016(1):390-396

Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX.

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http://dx.doi.org/10.1182/asheducation-2016.1.390DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142511PMC
December 2016

Recent advances in T-cell immunotherapy for haematological malignancies.

Br J Haematol 2017 03 29;176(5):688-704. Epub 2016 Nov 29.

Center for Cell and Gene Therapy, Baylor College of Medicine, Houston Methodist Hospital and Texas Children's Hospital, Houston, TX, USA.

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http://dx.doi.org/10.1111/bjh.14470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318250PMC
March 2017

Forecasting Cytokine Storms with New Predictive Biomarkers.

Cancer Discov 2016 06;6(6):579-80

Center for Cell and Gene Therapy, Baylor College of Medicine, Houston Methodist Hospital and Texas Children's Hospital, Houston, Texas.

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http://dx.doi.org/10.1158/2159-8290.CD-16-0493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894532PMC
June 2016

T cells for viral infections after allogeneic hematopoietic stem cell transplant.

Blood 2016 06 20;127(26):3331-40. Epub 2016 May 20.

Center for Cell and Gene Therapy, Baylor College of Medicine, Houston Methodist Hospital and Texas Children's Hospital, Houston, TX.

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http://dx.doi.org/10.1182/blood-2016-01-628982DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929925PMC
June 2016

Policy: Global standards for stem-cell research.

Nature 2016 05;533(7603):311-3

Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts, USA, and a member of the steering committee of the International Society for Stem Cell Research's Guidelines Task Force.

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http://dx.doi.org/10.1038/533311aDOI Listing
May 2016

Serial Activation of the Inducible Caspase 9 Safety Switch After Human Stem Cell Transplantation.

Mol Ther 2016 Apr 28;24(4):823-31. Epub 2015 Dec 28.

Center for Cell and Gene Therapy, Baylor College of Medicine, Texas Children's Hospital and Houston Methodist Hospital, Houston, Texas, USA.

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http://dx.doi.org/10.1038/mt.2015.234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886936PMC
April 2016

Clonal Dynamics In Vivo of Virus Integration Sites of T Cells Expressing a Safety Switch.

Mol Ther 2016 04 7;24(4):736-45. Epub 2015 Dec 7.

Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, Texas, USA.

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http://dx.doi.org/10.1038/mt.2015.217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886929PMC
April 2016

CAR-T Cell Therapy for Lymphoma.

Annu Rev Med 2016 26;67:165-83. Epub 2015 Aug 26.

Center for Cell and Gene Therapy, Houston Methodist Hospital, Texas Children's Hospital, and Baylor College of Medicine, Houston, Texas 77030.

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http://dx.doi.org/10.1146/annurev-med-051914-021702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732525PMC
October 2016

Antigen-specific T cell therapies for cancer.

Hum Mol Genet 2015 Oct 9;24(R1):R67-73. Epub 2015 Jul 9.

Center for Cell and Gene Therapy, Baylor College of Medicine, Houston Methodist Hospital and Texas Children's Hospital, Houston, TX 77030, USA.

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https://academic.oup.com/hmg/article-lookup/doi/10.1093/hmg/
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http://dx.doi.org/10.1093/hmg/ddv270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572005PMC
October 2015

Antigen-specific T cell therapies for cancer.

Hum Mol Genet 2015 Oct 9;24(R1):R67-73. Epub 2015 Jul 9.

Center for Cell and Gene Therapy, Baylor College of Medicine, Houston Methodist Hospital and Texas Children's Hospital, Houston, TX 77030, USA.

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https://academic.oup.com/hmg/article-lookup/doi/10.1093/hmg/
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http://dx.doi.org/10.1093/hmg/ddv270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572005PMC
October 2015

Tumor indoleamine 2,3-dioxygenase (IDO) inhibits CD19-CAR T cells and is downregulated by lymphodepleting drugs.

Blood 2015 Jun 4;125(25):3905-16. Epub 2015 May 4.

Center for Cell and Gene Therapy, Houston Methodist Hospital, Texas Children's Hospital, and Baylor College of Medicine, Houston, TX; and Medicine, and.

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http://dx.doi.org/10.1182/blood-2015-01-621474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473118PMC
June 2015

CMV-specific T cells generated from naïve T cells recognize atypical epitopes and may be protective in vivo.

Sci Transl Med 2015 Apr;7(285):285ra63

Center for Cell and Gene Therapy, Baylor College of Medicine, Texas Children's Hospital, and Houston Methodist Hospital, Houston, TX 77030, USA. Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX 77030, USA. Program for Cell Enhancement and Technologies for Immunotherapy, The Sheikh Zayed Institute for Pediatric Surgical Innovation, the Center for Cancer and Immunology Research, and the Division of Blood and Marrow Transplantation, Children's National Health System and The George Washington University, Washington, DC 20052, USA. Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA. Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.

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http://dx.doi.org/10.1126/scitranslmed.aaa2546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479400PMC
April 2015

Human Epidermal Growth Factor Receptor 2 (HER2) -Specific Chimeric Antigen Receptor-Modified T Cells for the Immunotherapy of HER2-Positive Sarcoma.

J Clin Oncol 2015 May 23;33(15):1688-96. Epub 2015 Mar 23.

Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, and Stephen Gottschalk, Center for Cell and Gene Therapy, Texas Children's Hospital, Baylor College of Medicine, Houston Methodist Hospital; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, John Hicks, Nino Rainusso, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Meng-Fen Wu, Hao Liu, John Hicks, Nino Rainusso, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Baylor College of Medicine; Peter Anderson, The University of Texas MD Anderson Cancer Center, Houston, TX; Peter Anderson, Levine Children's Hospital, Levine Cancer Institute, Carolinas Healthcare System, Charlotte NC; and Winfried S. Wels, Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.

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http://dx.doi.org/10.1200/JCO.2014.58.0225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429176PMC
May 2015

Graft versus leukemia response without graft-versus-host disease elicited by adoptively transferred multivirus-specific T-cells.

Mol Ther 2015 Jan 30;23(1):179-83. Epub 2014 Sep 30.

1] Center for Cell and Gene Therapy, Baylor College of Medicine, Texas Children's Hospital and Houston Methodist Hospital, Houston, Texas, USA [2] Program for Cell Enhancement and Technologies for Immunotherapy, Sheikh Zayed Institute for Pediatric Surgical Innovation, and Center for Cancer and Immunology Research, Children's National Health System, Washington, District of Columbia, USA.

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http://dx.doi.org/10.1038/mt.2014.192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426803PMC
January 2015

Epstein-Barr virus lymphoproliferative disease after hematopoietic stem cell transplant.

Curr Opin Hematol 2014 Nov;21(6):476-81

Center for Cell and Gene Therapy, Baylor College of Medicine, Houston Methodist Hospital and Texas Children's Hospital, Houston, Texas, USA.

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http://dx.doi.org/10.1097/MOH.0000000000000083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257464PMC
November 2014

Reply to S. Yuan et al.

J Clin Oncol 2014 Sep 21;32(25):2820-1. Epub 2014 Jul 21.

Center for Cell and Gene Therapy, Dan L. Duncan Cancer Center, Baylor College of Medicine; and Texas Children's Hospital, Houston, TX.

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http://dx.doi.org/10.1200/JCO.2014.56.8469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145187PMC
September 2014

Closely related T-memory stem cells correlate with in vivo expansion of CAR.CD19-T cells and are preserved by IL-7 and IL-15.

Blood 2014 Jun 29;123(24):3750-9. Epub 2014 Apr 29.

Center for Cell and Gene Therapy, Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX; Department of Medicine, Baylor College of Medicine, Houston, TX; Texas Children's Hospital, Houston, TX.

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http://www.bloodjournal.org/content/bloodjournal/123/24/3750
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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2014-01-55
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http://dx.doi.org/10.1182/blood-2014-01-552174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055922PMC
June 2014

Reversal of tumor immune inhibition using a chimeric cytokine receptor.

Mol Ther 2014 Jun 20;22(6):1211-1220. Epub 2014 Mar 20.

Center for Cell and Gene Therapy, Baylor College of Medicine, Texas Children's Hospital and Houston Methodist Hospital, Houston, Texas, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S15250016163070
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http://dx.doi.org/10.1038/mt.2014.47DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048899PMC
June 2014

Complementation of antigen-presenting cells to generate T lymphocytes with broad target specificity.

J Immunother 2014 May;37(4):193-203

*Center for Cell and Gene Therapy, Texas Children's Hospital, The Methodist Hospital, Baylor College of Medicine, Houston, TX †Interdepartmental Program in Translational Biology and Medicine ‡Medical Scientist Training Program Departments of §Pediatrics ¶Medicine #Molecular Virology and Microbiology ∥Pathology and Immunology, Baylor College of Medicine, Houston, TX.

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http://dx.doi.org/10.1097/CJI.0000000000000014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133102PMC
May 2014

Systemic inflammatory response syndrome after administration of unmodified T lymphocytes.

Mol Ther 2014 Jun 21;22(6):1134-1138. Epub 2014 Mar 21.

Center for Cell and Gene Therapy, Baylor College of Medicine, Houston Methodist Hospital, Texas Children's Hospital, Houston, Texas, USA. Electronic address:

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http://dx.doi.org/10.1038/mt.2014.48DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048900PMC
June 2014

Immunotherapy: opportunities, risks and future perspectives.

Cytotherapy 2014 Apr;16(4 Suppl):S120-9

Baylor College of Medicine and Pediatrics, Houston, Texas, USA.

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http://dx.doi.org/10.1016/j.jcyt.2014.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108615PMC
April 2014

Antiviral T-cell therapy.

Immunol Rev 2014 Mar;258(1):12-29

Center for Cell and Gene Therapy, Baylor College of Medicine, Houston Methodist Hospital and Texas Children's Hospital, Houston, TX, USA.

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http://dx.doi.org/10.1111/imr.12138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927231PMC
March 2014

Combining drugs and biologics to treat nasopharyngeal cancer.

Authors:
Helen E Heslop

Mol Ther 2014 Jan;22(1):8-9

Center for Cell and Gene Therapy, Baylor College of Medicine, Texas Children's Hospital, and Houston Methodist Hospital, Houston, Texas, USA.

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http://dx.doi.org/10.1038/mt.2013.272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978800PMC
January 2014

Sustained complete responses in patients with lymphoma receiving autologous cytotoxic T lymphocytes targeting Epstein-Barr virus latent membrane proteins.

J Clin Oncol 2014 Mar 16;32(8):798-808. Epub 2013 Dec 16.

Catherine M. Bollard, Stephen Gottschalk, Vicky Torrano, Oumar Diouf, Stephanie Ku, Yasmin Hazrat, George Carrum, Carlos Ramos, Hao Liu, Meng-Fen Wu, Andrea M. Sheehan, Adrian P. Gee, Malcolm K. Brenner, Helen E. Heslop, and Cliona M. Rooney, Baylor College of Medicine and Texas Children's Hospital; Catherine M. Bollard, Stephen Gottschalk, Vicky Torrano, Oumar Diouf, Stephanie Ku, Yasmin Hazrat, George Carrum, Carlos Ramos, Hao Liu, Meng-Fen Wu, Daniel Lee, Andrea M. Sheehan, Youli Zu, Adrian P. Gee, Malcolm K. Brenner, Helen E. Heslop, and Cliona M. Rooney, Methodist Hospital; Luis Fayad, Elizabeth J. Shpall, and Barbara Pro, MD Anderson Cancer Center, Houston, TX; and Daniel Lee and Youli Zu, Weill Medical College of Cornell University, New York, NY.

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http://dx.doi.org/10.1200/JCO.2013.51.5304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940538PMC
March 2014

T lymphocytes targeting native receptors.

Immunol Rev 2014 Jan;257(1):39-55

Center for Cell and Gene Therapy, Baylor College of Medicine, Houston Methodist Hospital and Texas Children's Hospital, Houston, TX, USA.

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http://dx.doi.org/10.1111/imr.12133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869095PMC
January 2014

T-cell therapy for viral infections.

Hematology Am Soc Hematol Educ Program 2013 ;2013:342-7

1Center for Cell and Gene Therapy, Baylor College of Medicine, Texas Children's Hospital, The Methodist Hospital, Houston, TX.

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http://dx.doi.org/10.1182/asheducation-2013.1.342DOI Listing
December 2014

Kinetics of tumor destruction by chimeric antigen receptor-modified T cells.

Mol Ther 2014 Mar 28;22(3):623-633. Epub 2013 Nov 28.

Center for Cell and Gene Therapy, Baylor College of Medicine, Texas Children's Hospital, and Houston Methodist Hospital, Houston, Texas, USA. Electronic address:

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http://dx.doi.org/10.1038/mt.2013.262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945803PMC
March 2014

Combinational targeting offsets antigen escape and enhances effector functions of adoptively transferred T cells in glioblastoma.

Mol Ther 2013 Nov 13;21(11):2087-101. Epub 2013 Aug 13.

1] Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, Texas, USA [2] Texas Children's Cancer Center, Baylor College of Medicine, Houston, Texas, USA [3] Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA.

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http://dx.doi.org/10.1038/mt.2013.185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831041PMC
November 2013

Genetic engineering of T-cell receptors: TCR takes to titin.

Authors:
Helen E Heslop

Blood 2013 Aug;122(6):853-4

Baylor College of Medicine.

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http://dx.doi.org/10.1182/blood-2013-06-509604DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739034PMC
August 2013

TanCAR: A Novel Bispecific Chimeric Antigen Receptor for Cancer Immunotherapy.

Mol Ther Nucleic Acids 2013 Jul 9;2:e105. Epub 2013 Jul 9.

1] Center for Cell and Gene Therapy, Baylor College of Medicine, Texas Children's Hospital and The Methodist Hospital, Houston, Texas, USA [2] Texas Children's Cancer and Hematology Centers, Baylor College of Medicine, Houston, Texas, USA [3] Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA.

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http://dx.doi.org/10.1038/mtna.2013.32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731887PMC
July 2013

Pharmacotherapy versus T lymphocytes for CMV.

Authors:
Helen E Heslop

Blood 2013 May;121(18):3544-5

Baylor College of Medicine, USA.

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http://dx.doi.org/10.1182/blood-2013-03-487249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643755PMC
May 2013

New approaches in alternative donor transplantation.

Biol Blood Marrow Transplant 2013 Jan 27;19(1 Suppl):S91-6. Epub 2012 Oct 27.

Department of Pathology, Medical School, Stanford University, Stanford, California, USA.

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http://dx.doi.org/10.1016/j.bbmt.2012.10.027DOI Listing
January 2013

T-cell therapy in the treatment of post-transplant lymphoproliferative disease.

Nat Rev Clin Oncol 2012 Sep 17;9(9):510-9. Epub 2012 Jul 17.

Center for Cell and Gene Therapy, Department of Pediatrics, Baylor College of Medicine, The Methodist Hospital and Texas Children's Hospital, 1102 Bates Street, Houston, TX 77030, USA.

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http://dx.doi.org/10.1038/nrclinonc.2012.111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743122PMC
September 2012

Equal-opportunity treatment of EBV-PTLD.

Authors:
Helen E Heslop

Blood 2012 Mar;119(11):2436-8

Baylor College of Medicine, USA.

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http://dx.doi.org/10.1182/blood-2012-01-397828DOI Listing
March 2012

Excellent survival after sibling or unrelated donor stem cell transplantation for chronic granulomatous disease.

J Allergy Clin Immunol 2012 Jan 12;129(1):176-83. Epub 2011 Nov 12.

Center for Cell and Gene Therapy, Baylor College of Medicine, The Methodist Hospital, and Texas Children's Hospital, Houston, Tex 77030, USA.

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http://dx.doi.org/10.1016/j.jaci.2011.10.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173521PMC
January 2012

Aggressive peripheral CD70-positive T-cell lymphoma associated with severe chronic active EBV infection.

Pediatr Blood Cancer 2012 Oct 12;59(4):758-61. Epub 2011 Oct 12.

Center for Cell and Gene Therapy, Baylor College of Medicine, Texas Children's Hospital, The Methodist Hospital, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1002/pbc.23352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258475PMC
October 2012

TCR expression; quantitative easing by CD3.

Authors:
Helen E Heslop

Blood 2011 Sep;118(13):3452-3

Baylor College of Medicine, TX, USA.

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http://dx.doi.org/10.1182/blood-2011-08-369025DOI Listing
September 2011