Helen Duhart

Helen Duhart

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Helen Duhart

Helen Duhart

Publications by authors named "Helen Duhart"

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Expression changes of dopaminergic system-related genes in PC12 cells induced by manganese, silver, or copper nanoparticles.

Neurotoxicology 2009 Nov 23;30(6):926-33. Epub 2009 Sep 23.

Neurochemistry Laboratory, Division of Neurotoxicology, National Center for Toxicological Research, U.S. Food & Drug Administration, 3900 NCTR Rd., Jefferson, AR 72079-9502, USA.

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http://dx.doi.org/10.1016/j.neuro.2009.09.005DOI Listing
November 2009

Acrylamide decreased dopamine levels and increased 3-nitrotyrosine (3-NT) levels in PC 12 cells.

Neurosci Lett 2009 Jul 11;458(2):89-92. Epub 2009 Apr 11.

Neurochemistry Laboratory, Division of Neurotoxicology, National Center for Toxicological Research, Food and Drug Administration, Jefferson, AR 72079, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S030439400900480
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http://dx.doi.org/10.1016/j.neulet.2009.04.016DOI Listing
July 2009

Comparison of the time courses of selective gene expression and dopaminergic depletion induced by MPP+ in MN9D cells.

Neurochem Int 2008 May 4;52(6):1037-43. Epub 2007 Nov 4.

Neurochemistry Laboratory, Division of Neurotoxicology, National Center for Toxicological Research, Jefferson, AR 72079, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S019701860700305
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http://dx.doi.org/10.1016/j.neuint.2007.10.017DOI Listing
May 2008

Gene expression profiling of MPP+-treated MN9D cells: a mechanism of toxicity study.

Neurotoxicology 2007 Sep 12;28(5):979-87. Epub 2007 Mar 12.

Neurochemistry Laboratory, Division of Neurotoxicology, HFT-132, National Center for Toxicological Research/FDA, 3900 NCTR Road, Jefferson, AR 72079, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S0161813X0700048
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http://dx.doi.org/10.1016/j.neuro.2007.02.013DOI Listing
September 2007

The interaction of manganese nanoparticles with PC-12 cells induces dopamine depletion.

Toxicol Sci 2006 Aug 19;92(2):456-63. Epub 2006 May 19.

Applied Biotechnology Branch, Human Effectiveness Directorate, Air Force Research Laboratory, Wright-Patterson AFB, Ohio 45431, USA.

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http://dx.doi.org/10.1093/toxsci/kfl020DOI Listing
August 2006

Cocaine induces a differential dose-dependent alteration in the expression profile of immediate early genes, transcription factors, and caspases in PC12 cells: a possible mechanism of neurotoxic damage in cocaine addiction.

Ann N Y Acad Sci 2005 Aug;1053:482-90

South Texas Veterans Health Care System and Department of Medicine, University of Texas, Health Science Center, San Antonio, Texas 78229, USA.

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http://dx.doi.org/10.1111/j.1749-6632.2005.tb00058.xDOI Listing
August 2005

A microarray study of MPP+-treated PC12 Cells: Mechanisms of toxicity (MOT) analysis using bioinformatics tools.

BMC Bioinformatics 2005 Jul 15;6 Suppl 2:S8. Epub 2005 Jul 15.

Division of Neurotoxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, 3900 NCTR Road, Jefferson, Arkansas 72079, USA.

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http://dx.doi.org/10.1186/1471-2105-6-S2-S8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1637031PMC
July 2005

Role of mitochondrial dysfunction in neurotoxicity of MPP+: partial protection of PC12 cells by acetyl-L-carnitine.

Ann N Y Acad Sci 2004 Oct;1025:267-73

Research and Development, Sigma-tau HealthScience S.p.A., Pomezia 00040, Italy.

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http://dx.doi.org/10.1196/annals.1316.033DOI Listing
October 2004

Neuroprotection or neurotoxicity: impact of discontinuous dose-response curves on risk assessment.

Ann N Y Acad Sci 2003 May;993:158; discussion 159-60

Division of Neurotoxicology, National Center for Toxicological Research/FDA, Jefferson, Arkansas 72079, USA.

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May 2003

3-nitropropionic acid inhibition of succinate dehydrogenase (complex II) activity in cultured Chinese hamster ovary cells: antagonism by L-carnitine.

Ann N Y Acad Sci 2003 May;993:305-12; discussion 345-9

Laboratory of Experimental Neuropathology, Division of Neurotoxicology, National Center for Toxicological Research, USFDA, Arkansas 72079, USA.

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http://dx.doi.org/10.1111/j.1749-6632.2003.tb07538.xDOI Listing
May 2003

Cocaine induces a dose-dependent alteration in the expression of immediate early genes c-fos and SP-1 and in nuclear factor NF-kappabeta in PC12 cells.

Ann N Y Acad Sci 2003 May;993:362; discussion 387-93

Division of Neurotoxicology, US FDA/NCTR, Jefferson, Arkansas 72079, USA.

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http://dx.doi.org/10.1111/j.1749-6632.2003.tb07545.xDOI Listing
May 2003

Methamphetamine-induced dopaminergic neurotoxicity and production of peroxynitrite are potentiated in nerve growth factor differentiated pheochromocytoma 12 cells.

Ann N Y Acad Sci 2002 Jun;965:204-13

Neurochemistry Laboratory, Division of Neurotoxicology, National Center for Toxicological Resarch/US FDA, Jefferson, Arkansas 72079, USA.

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http://dx.doi.org/10.1111/j.1749-6632.2002.tb04162.xDOI Listing
June 2002