Heinz-Josef Lenz

Heinz-Josef Lenz

UNVERIFIED PROFILE

Are you Heinz-Josef Lenz?   Register this Author

Register author
Heinz-Josef Lenz

Heinz-Josef Lenz

Publications by authors named "Heinz-Josef Lenz"

Are you Heinz-Josef Lenz?   Register this Author

100Publications

2581Reads

10Profile Views

Outlook: Immunotherapy in Gastrointestinal Carcinoma - Innovative Strategies.

Oncol Res Treat 2018 26;41(5):313-315. Epub 2018 Apr 26.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000489047DOI Listing
August 2019

The current state of molecular testing in the treatment of patients with solid tumors, 2019.

CA Cancer J Clin 2019 Jul 22;69(4):305-343. Epub 2019 May 22.

Professor of Medicine and Oncology, Director, Ruesch Center for the Cure of Gastrointestinal Cancers, Lombardi Comprehensive Cancer Institute, MedStar Georgetown Cancer Institute, Washington, DC.

View Article

Download full-text PDF

Source
https://onlinelibrary.wiley.com/doi/abs/10.3322/caac.21560
Publisher Site
http://dx.doi.org/10.3322/caac.21560DOI Listing
July 2019

Quantitative evidence for early metastatic seeding in colorectal cancer.

Nat Genet 2019 Jul 17;51(7):1113-1122. Epub 2019 Jun 17.

Department of Medicine, Division of Oncology, Stanford University School of Medicine, Stanford, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41588-019-0423-xDOI Listing
July 2019

Reply to S. Sorscher.

J Clin Oncol 2019 Jul 3:JCO1901366. Epub 2019 Jul 3.

Federico Innocenti, MD, PhD, University of North Carolina at Chapel Hill, Chapel Hill, NC; Fang-Shu Ou, PhD, Mayo Clinic Minnesota, Rochester, MN; Xueping Qu, PhD, Genentech, South San Francisco, CA; Tyler Zemla, MS, Mayo Clinic Minnesota, Rochester, MN; Donna Niedzwiecki, PhD, Duke University, Durham, NC; Rachel Tam, PhD and Shilpi Mahajan, PhD, Genentech, South San Francisco, CA; Richard M. Goldberg, MD, West Virginia University Cancer Institute, Morgantown, WV; Monica M. Bertagnolli, MD, Dana-Farber Cancer Institute, Boston, MA; Charles David Blanke, MD, Oregon Health and Science University Hospital, Portland, OR; Hanna Sanoff, MD, University of North Carolina at Chapel Hill, Chapel Hill, NC; James Atkins, MD, Bon Secours Health System, Richmond, VA; Blasé Polite, MD, University of Chicago Medical Center, Chicago, IL; Alan P. Venook, MD, University of California San Francisco, San Francisco, CA; Heinz-Josef Lenz, MD, University of Southern California, Los Angeles, CA; and Omar Kabbarah, PhD, ORIC Pharmaceuticals, South San Francisco, CA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.19.01366DOI Listing
July 2019

The impact of panitumumab treatment on survival and quality of life in patients with wild-type metastatic colorectal cancer.

Cancer Manag Res 2019 28;11:5911-5924. Epub 2019 Jun 28.

Division of Medical Oncology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2147/CMAR.S186042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607986PMC
June 2019

MAVERICC, a Randomized, Biomarker-stratified, Phase II Study of mFOLFOX6-Bevacizumab versus FOLFIRI-Bevacizumab as First-line Chemotherapy in Metastatic Colorectal Cancer.

Clin Cancer Res 2019 May 17;25(10):2988-2995. Epub 2018 Sep 17.

Norris Comprehensive Cancer Center, Keck School of Medicine, Department of Medicine, University of Southern California, Los Angeles, California.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-18-1221DOI Listing
May 2019

Genetic variants in CCL5 and CCR5 genes and serum VEGF-A levels predict efficacy of bevacizumab in metastatic colorectal cancer patients.

Int J Cancer 2019 05 14;144(10):2567-2577. Epub 2018 Dec 14.

Division of Medical Oncology Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/ijc.31968
Publisher Site
http://dx.doi.org/10.1002/ijc.31968DOI Listing
May 2019

Impact of polymorphisms within genes involved in regulating DNA methylation in patients with metastatic colorectal cancer enrolled in three independent, randomised, open-label clinical trials: a meta-analysis from TRIBE, MAVERICC and FIRE-3.

Eur J Cancer 2019 Apr 7;111:138-147. Epub 2019 Mar 7.

Division of Medical Oncology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; Department of Preventive Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejca.2019.01.105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436973PMC
April 2019

A phase 1b study evaluating the safety and pharmacokinetics of regorafenib in combination with cetuximab in patients with advanced solid tumors.

Int J Cancer 2019 Apr 8. Epub 2019 Apr 8.

Division of Medical Oncology, University of Southern California/Norris Comprehensive Center, Los Angeles, CA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ijc.32317DOI Listing
April 2019

Novel Common Genetic Susceptibility Loci for Colorectal Cancer.

Authors:
Stephanie L Schmit Christopher K Edlund Fredrick R Schumacher Jian Gong Tabitha A Harrison Jeroen R Huyghe Chenxu Qu Marilena Melas David J Van Den Berg Hansong Wang Stephanie Tring Sarah J Plummer Demetrius Albanes M Henar Alonso Christopher I Amos Kristen Anton Aaron K Aragaki Volker Arndt Elizabeth L Barry Sonja I Berndt Stéphane Bezieau Stephanie Bien Amanda Bloomer Juergen Boehm Marie-Christine Boutron-Ruault Hermann Brenner Stefanie Brezina Daniel D Buchanan Katja Butterbach Bette J Caan Peter T Campbell Christopher S Carlson Jose E Castelao Andrew T Chan Jenny Chang-Claude Stephen J Chanock Iona Cheng Ya-Wen Cheng Lee Soo Chin James M Church Timothy Church Gerhard A Coetzee Michelle Cotterchio Marcia Cruz Correa Keith R Curtis David Duggan Douglas F Easton Dallas English Edith J M Feskens Rocky Fischer Liesel M FitzGerald Barbara K Fortini Lars G Fritsche Charles S Fuchs Manuela Gago-Dominguez Manish Gala Steven J Gallinger W James Gauderman Graham G Giles Edward L Giovannucci Stephanie M Gogarten Clicerio Gonzalez-Villalpando Elena M Gonzalez-Villalpando William M Grady Joel K Greenson Andrea Gsur Marc Gunter Christopher A Haiman Jochen Hampe Sophia Harlid John F Harju Richard B Hayes Philipp Hofer Michael Hoffmeister John L Hopper Shu-Chen Huang Jose Maria Huerta Thomas J Hudson David J Hunter Gregory E Idos Motoki Iwasaki Rebecca D Jackson Eric J Jacobs Sun Ha Jee Mark A Jenkins Wei-Hua Jia Shuo Jiao Amit D Joshi Laurence N Kolonel Suminori Kono Charles Kooperberg Vittorio Krogh Tilman Kuehn Sébastien Küry Andrea LaCroix Cecelia A Laurie Flavio Lejbkowicz Mathieu Lemire Heinz-Josef Lenz David Levine Christopher I Li Li Li Wolfgang Lieb Yi Lin Noralane M Lindor Yun-Ru Liu Fotios Loupakis Yingchang Lu Frank Luh Jing Ma Christoph Mancao Frank J Manion Sanford D Markowitz Vicente Martin Koichi Matsuda Keitaro Matsuo Kevin J McDonnell Caroline E McNeil Roger Milne Antonio J Molina Bhramar Mukherjee Neil Murphy Polly A Newcomb Kenneth Offit Hanane Omichessan Domenico Palli Jesus P Paredes Cotoré Julyann Pérez-Mayoral Paul D Pharoah John D Potter Conghui Qu Leon Raskin Gad Rennert Hedy S Rennert Bridget M Riggs Clemens Schafmayer Robert E Schoen Thomas A Sellers Daniela Seminara Gianluca Severi Wei Shi David Shibata Xiao-Ou Shu Erin M Siegel Martha L Slattery Melissa Southey Zsofia K Stadler Mariana C Stern Sebastian Stintzing Darin Taverna Stephen N Thibodeau Duncan C Thomas Antonia Trichopoulou Shoichiro Tsugane Cornelia M Ulrich Franzel J B van Duijnhoven Bethany van Guelpan Joseph Vijai Jarmo Virtamo Stephanie J Weinstein Emily White Aung Ko Win Alicja Wolk Michael Woods Anna H Wu Kana Wu Yong-Bing Xiang Yun Yen Brent W Zanke Yi-Xin Zeng Ben Zhang Niha Zubair Sun-Seog Kweon Jane C Figueiredo Wei Zheng Loic Le Marchand Annika Lindblom Victor Moreno Ulrike Peters Graham Casey Li Hsu David V Conti Stephen B Gruber

J Natl Cancer Inst 2019 Feb;111(2):146-157

Department of Preventive Medicine, USC Norris Comprehensive Cancer Center.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jnci/djy099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555904PMC
February 2019

B cell and B cell-related pathways for novel cancer treatments.

Cancer Treat Rev 2019 Feb 3;73:10-19. Epub 2018 Dec 3.

Division of Medical Oncology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90033, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ctrv.2018.12.001DOI Listing
February 2019

Safety and Tolerability of c-MET Inhibitors in Cancer.

Drug Saf 2019 02;42(2):211-233

Division of Medical Oncology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Suite 5410, Los Angeles, CA, 90033, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s40264-018-0780-xDOI Listing
February 2019

The safety and efficacy of trifluridine-tipiracil for metastatic colorectal cancer: A pharmacy perspective.

Am J Health Syst Pharm 2019 Feb;76(6):339-348

USC Norris Comprehensive Cancer Center, Los Angeles, CA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ajhp/zxy006DOI Listing
February 2019

What Should We Do Better? Lessons from Negative Results of a Biomarker Validation Study.

J Natl Cancer Inst 2019 Jan 14. Epub 2019 Jan 14.

Division of Medical Oncology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jnci/djy217DOI Listing
January 2019

Shared heritability and functional enrichment across six solid cancers.

Authors:
Xia Jiang Hilary K Finucane Fredrick R Schumacher Stephanie L Schmit Jonathan P Tyrer Younghun Han Kyriaki Michailidou Corina Lesseur Karoline B Kuchenbaecker Joe Dennis David V Conti Graham Casey Mia M Gaudet Jeroen R Huyghe Demetrius Albanes Melinda C Aldrich Angeline S Andrew Irene L Andrulis Hoda Anton-Culver Antonis C Antoniou Natalia N Antonenkova Susanne M Arnold Kristan J Aronson Banu K Arun Elisa V Bandera Rosa B Barkardottir Daniel R Barnes Jyotsna Batra Matthias W Beckmann Javier Benitez Sara Benlloch Andrew Berchuck Sonja I Berndt Heike Bickeböller Stephanie A Bien Carl Blomqvist Stefania Boccia Natalia V Bogdanova Stig E Bojesen Manjeet K Bolla Hiltrud Brauch Hermann Brenner James D Brenton Mark N Brook Joan Brunet Hans Brunnström Daniel D Buchanan Barbara Burwinkel Ralf Butzow Gabriella Cadoni Trinidad Caldés Maria A Caligo Ian Campbell Peter T Campbell Géraldine Cancel-Tassin Lisa Cannon-Albright Daniele Campa Neil Caporaso André L Carvalho Andrew T Chan Jenny Chang-Claude Stephen J Chanock Chu Chen David C Christiani Kathleen B M Claes Frank Claessens Judith Clements J Margriet Collée Marcia Cruz Correa Fergus J Couch Angela Cox Julie M Cunningham Cezary Cybulski Kamila Czene Mary B Daly Anna deFazio Peter Devilee Orland Diez Manuela Gago-Dominguez Jenny L Donovan Thilo Dörk Eric J Duell Alison M Dunning Miriam Dwek Diana M Eccles Christopher K Edlund Digna R Velez Edwards Carolina Ellberg D Gareth Evans Peter A Fasching Robert L Ferris Triantafillos Liloglou Jane C Figueiredo Olivia Fletcher Renée T Fortner Florentia Fostira Silvia Franceschi Eitan Friedman Steven J Gallinger Patricia A Ganz Judy Garber José A García-Sáenz Simon A Gayther Graham G Giles Andrew K Godwin Mark S Goldberg David E Goldgar Ellen L Goode Marc T Goodman Gary Goodman Kjell Grankvist Mark H Greene Henrik Gronberg Jacek Gronwald Pascal Guénel Niclas Håkansson Per Hall Ute Hamann Freddie C Hamdy Robert J Hamilton Jochen Hampe Aage Haugen Florian Heitz Rolando Herrero Peter Hillemanns Michael Hoffmeister Estrid Høgdall Yun-Chul Hong John L Hopper Richard Houlston Peter J Hulick David J Hunter David G Huntsman Gregory Idos Evgeny N Imyanitov Sue Ann Ingles Claudine Isaacs Anna Jakubowska Paul James Mark A Jenkins Mattias Johansson Mikael Johansson Esther M John Amit D Joshi Radka Kaneva Beth Y Karlan Linda E Kelemen Tabea Kühl Kay-Tee Khaw Elza Khusnutdinova Adam S Kibel Lambertus A Kiemeney Jeri Kim Susanne K Kjaer Julia A Knight Manolis Kogevinas Zsofia Kote-Jarai Stella Koutros Vessela N Kristensen Jolanta Kupryjanczyk Martin Lacko Stephan Lam Diether Lambrechts Maria Teresa Landi Philip Lazarus Nhu D Le Eunjung Lee Flavio Lejbkowicz Heinz-Josef Lenz Goska Leslie Davor Lessel Jenny Lester Douglas A Levine Li Li Christopher I Li Annika Lindblom Noralane M Lindor Geoffrey Liu Fotios Loupakis Jan Lubiński Lovise Maehle Christiane Maier Arto Mannermaa Loic Le Marchand Sara Margolin Taymaa May Lesley McGuffog Alfons Meindl Pooja Middha Austin Miller Roger L Milne Robert J MacInnis Francesmary Modugno Marco Montagna Victor Moreno Kirsten B Moysich Lorelei Mucci Kenneth Muir Anna Marie Mulligan Katherine L Nathanson David E Neal Andrew R Ness Susan L Neuhausen Heli Nevanlinna Polly A Newcomb Lisa F Newcomb Finn Cilius Nielsen Liene Nikitina-Zake Børge G Nordestgaard Robert L Nussbaum Kenneth Offit Edith Olah Ali Amin Al Olama Olufunmilayo I Olopade Andrew F Olshan Håkan Olsson Ana Osorio Hardev Pandha Jong Y Park Nora Pashayan Michael T Parsons Tanja Pejovic Kathryn L Penney Wilbert H M Peters Catherine M Phelan Amanda I Phipps Dijana Plaseska-Karanfilska Miranda Pring Darya Prokofyeva Paolo Radice Kari Stefansson Susan J Ramus Leon Raskin Gad Rennert Hedy S Rennert Elizabeth J van Rensburg Marjorie J Riggan Harvey A Risch Angela Risch Monique J Roobol Barry S Rosenstein Mary Anne Rossing Kim De Ruyck Emmanouil Saloustros Dale P Sandler Elinor J Sawyer Matthew B Schabath Johanna Schleutker Marjanka K Schmidt V Wendy Setiawan Hongbing Shen Erin M Siegel Weiva Sieh Christian F Singer Martha L Slattery Karina Dalsgaard Sorensen Melissa C Southey Amanda B Spurdle Janet L Stanford Victoria L Stevens Sebastian Stintzing Jennifer Stone Karin Sundfeldt Rebecca Sutphen Anthony J Swerdlow Eloiza H Tajara Catherine M Tangen Adonina Tardon Jack A Taylor M Dawn Teare Manuel R Teixeira Mary Beth Terry Kathryn L Terry Stephen N Thibodeau Mads Thomassen Line Bjørge Marc Tischkowitz Amanda E Toland Diana Torres Paul A Townsend Ruth C Travis Nadine Tung Shelley S Tworoger Cornelia M Ulrich Nawaid Usmani Celine M Vachon Els Van Nieuwenhuysen Ana Vega Miguel Elías Aguado-Barrera Qin Wang Penelope M Webb Clarice R Weinberg Stephanie Weinstein Mark C Weissler Jeffrey N Weitzel Catharine M L West Emily White Alice S Whittemore H-Erich Wichmann Fredrik Wiklund Robert Winqvist Alicja Wolk Penella Woll Michael Woods Anna H Wu Xifeng Wu Drakoulis Yannoukakos Wei Zheng Shanbeh Zienolddiny Argyrios Ziogas Kristin K Zorn Jacqueline M Lane Richa Saxena Duncan Thomas Rayjean J Hung Brenda Diergaarde James McKay Ulrike Peters Li Hsu Montserrat García-Closas Rosalind A Eeles Georgia Chenevix-Trench Paul J Brennan Christopher A Haiman Jacques Simard Douglas F Easton Stephen B Gruber Paul D P Pharoah Alkes L Price Bogdan Pasaniuc Christopher I Amos Peter Kraft Sara Lindström

Nat Commun 2019 01 25;10(1):431. Epub 2019 Jan 25.

Public Health Sciences Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., Seattle, WA, 98109-1024, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-018-08054-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347624PMC
January 2019

Reprogramming Exosomes as Nanoscale Controllers of Cellular Immunity.

J Am Chem Soc 2018 Dec 19;140(48):16413-16417. Epub 2018 Nov 19.

Department of Pharmacology and Pharmaceutical Sciences, School of Pharmacy , University of Southern California , Los Angeles , California 90089 , United States.

View Article

Download full-text PDF

Source
http://pubs.acs.org/doi/10.1021/jacs.8b10047
Publisher Site
http://dx.doi.org/10.1021/jacs.8b10047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469991PMC
December 2018

Impact of primary tumour location on efficacy of bevacizumab plus chemotherapy in metastatic colorectal cancer.

Br J Cancer 2018 12 29;119(12):1451-1455. Epub 2018 Nov 29.

University of Southern California, Norris Comprehensive Cancer Center, Keck School of Medicine, 1441 Eastlake Ave, Los Angeles, CA, 90033, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41416-018-0304-6
Publisher Site
http://dx.doi.org/10.1038/s41416-018-0304-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288128PMC
December 2018

Management of Advanced Small Bowel Cancer.

Curr Treat Options Oncol 2018 11 5;19(12):69. Epub 2018 Nov 5.

Division of Medical Oncology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Suite 3456, Los Angeles, CA, 90033, USA.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s11864-018-0592-3
Publisher Site
http://dx.doi.org/10.1007/s11864-018-0592-3DOI Listing
November 2018

Microsatellite instability in colorectal cancer: overview of its clinical significance and novel perspectives.

Clin Adv Hematol Oncol 2018 Nov;16(11):735-745

Levine Cancer Institute of the Carolinas HealthCare System, Charlotte, North Carolina.

View Article

Download full-text PDF

Source
November 2018

First-in-human phase I dose escalation study of MK-8033 in patients with advanced solid tumors.

Invest New Drugs 2018 10 29;36(5):860-868. Epub 2018 Jan 29.

Center for Oncology and Blood Disorders, Houston, TX, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10637-018-0567-zDOI Listing
October 2018

Molecular biomarkers in gastro-esophageal cancer: recent developments, current trends and future directions.

Cancer Cell Int 2018 11;18:99. Epub 2018 Jul 11.

1Division of Medical Oncology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Suite 5410, Los Angeles, CA 90033 USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12935-018-0594-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042434PMC
July 2018

Biomarker-driven and molecular targeted therapies for colorectal cancers.

Semin Oncol 2018 06 4;45(3):124-132. Epub 2017 Jul 4.

Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00937754173005
Publisher Site
http://dx.doi.org/10.1053/j.seminoncol.2017.06.003DOI Listing
June 2018

Outlooks on Epstein-Barr virus associated gastric cancer.

Cancer Treat Rev 2018 May 31;66:15-22. Epub 2018 Mar 31.

Division of Medical Oncology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, USA. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S03057372183003
Publisher Site
http://dx.doi.org/10.1016/j.ctrv.2018.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964025PMC
May 2018

The role of tumor angiogenesis as a therapeutic target in colorectal cancer.

Expert Rev Anticancer Ther 2018 03 19;18(3):251-266. Epub 2018 Jan 19.

a Medical Oncology Unit 1, Clinical and Experimental Oncology Department , Veneto Institute of Oncology IOV-IRCCS , Padua , Italy.

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/14737140.2018.1
Publisher Site
http://dx.doi.org/10.1080/14737140.2018.1428092DOI Listing
March 2018

Durable Clinical Benefit With Nivolumab Plus Ipilimumab in DNA Mismatch Repair-Deficient/Microsatellite Instability-High Metastatic Colorectal Cancer.

J Clin Oncol 2018 03 20;36(8):773-779. Epub 2018 Jan 20.

Michael J. Overman and Scott Kopetz, University of Texas MD Anderson Cancer Center, Houston, TX; Sara Lonardi, Istituto Oncologico Veneto, Istituto di Ricovero e Cura a Carattere Scientifico, Padova; Fabio Gelsomino, University Hospital of Modena, Modena; Massimo Aglietta, Institute for Cancer Research and Treatment of Candiolo, University of Torino Medical School, Turin, Italy; Ka Yeung Mark Wong, Sydney Medical School, University of Sydney, Sydney, New South Wales; Andrew Hill, Tasman Oncology Research, Ltd., Southport, Queensland, Australia; Heinz-Josef Lenz, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA; Michael A. Morse, Duke University Medical Center, Durham, NC; Eric Van Cutsem, University Hospitals Gasthuisberg Leuven and Katholieke Universiteit Leuven, Leuven; Alain Hendlisz, Institut Jules Bordet; Bart Neyns, Universitair Ziekenhuis Brussel, Brussels; Jean-Marie Ledeine, Bristol-Myers Squibb, Braine-L'Alleud, Belgium; Ray McDermott, St Vincent's University Hospital and Cancer Trials Ireland, Dublin, Ireland; Michael B. Sawyer, Cross Cancer Institute and University of Alberta, Edmonton, Alberta, Canada; Magali Svrcek and Thierry André, Hopital Saint Antoine, Assistance Publique Hôpitaux de Paris and Sorbonne Universités, Université Pierre et Marie Curie, Paris, France; and Rebecca A. Moss, Z. Alexander Cao, and Shital Kamble, Bristol-Myers Squibb, Princeton, NJ.

View Article

Download full-text PDF

Source
http://ascopubs.org/doi/10.1200/JCO.2017.76.9901
Publisher Site
http://dx.doi.org/10.1200/JCO.2017.76.9901DOI Listing
March 2018

Differentiation Therapy Targeting the β-Catenin/CBP Interaction in Pancreatic Cancer.

Cancers (Basel) 2018 Mar 29;10(4). Epub 2018 Mar 29.

Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/cancers10040095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923350PMC
March 2018

Colorectal cancer in 2017: Practice-changing updates in the adjuvant and metastatic setting.

Nat Rev Clin Oncol 2018 02 28;15(2):77-78. Epub 2017 Nov 28.

Division of Medical Oncology, Suite 3456, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, California 90033, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrclinonc.2017.185DOI Listing
February 2018

CXCL9, CXCL10, CXCL11/CXCR3 axis for immune activation - A target for novel cancer therapy.

Cancer Treat Rev 2018 Feb 26;63:40-47. Epub 2017 Nov 26.

Division of Medical Oncology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90033, United States. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ctrv.2017.11.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801162PMC
February 2018

Colorectal cancer: epigenetic alterations and their clinical implications.

Biochim Biophys Acta Rev Cancer 2017 Dec 20;1868(2):439-448. Epub 2017 Sep 20.

Division of Medical Oncology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; Department of Preventive Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbcan.2017.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757873PMC
December 2017

Randomized study of etirinotecan pegol versus irinotecan as second-line treatment for metastatic colorectal cancer.

Cancer Chemother Pharmacol 2017 Dec 17;80(6):1161-1169. Epub 2017 Oct 17.

UCLA Geffen School of Medicine, 201 S. Buena Vista Street, Suite 200, Burbank, CA, 91505, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00280-017-3438-yDOI Listing
December 2017

Molecular Landscape and Treatment Options for Patients with Metastatic Colorectal Cancer.

Indian J Surg Oncol 2017 Dec 27;8(4):580-590. Epub 2016 Jul 27.

Division of Medical Oncology, Norris Comprehensive Cancer Center, Shanon A. Carpenter Laboratory, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90033 USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s13193-016-0543-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705494PMC
December 2017

Trends in colorectal cancer mortality in hispanics: a SEER analysis.

Oncotarget 2017 Dec 19;8(65):108771-108777. Epub 2017 Oct 19.

Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.21938DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752479PMC
December 2017

Potential role of polymorphisms in the transporter genes ENT1 and MATE1/OCT2 in predicting TAS-102 efficacy and toxicity in patients with refractory metastatic colorectal cancer.

Eur J Cancer 2017 11 6;86:197-206. Epub 2017 Oct 6.

Division of Medical Oncology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90033, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejca.2017.08.033DOI Listing
November 2017

DNA mismatch repair deficiency and hereditary syndromes in Latino patients with colorectal cancer.

Cancer 2017 Oct 22;123(19):3732-3743. Epub 2017 Jun 22.

Department of Medicine, Division of Medical Oncology, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cncr.30790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610604PMC
October 2017

Understanding the role of primary tumour localisation in colorectal cancer treatment and outcomes.

Eur J Cancer 2017 10 5;84:69-80. Epub 2017 Aug 5.

USC Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejca.2017.07.016DOI Listing
October 2017

Comparative molecular analyses of left-sided colon, right-sided colon, and rectal cancers.

Oncotarget 2017 Oct 21;8(49):86356-86368. Epub 2017 Sep 21.

Ruesch Center for The Cure of Gastrointestinal Cancers, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.21169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689690PMC
October 2017

Mindfulness practice reduces cortisol blunting during chemotherapy: A randomized controlled study of colorectal cancer patients.

Cancer 2017 Aug 7;123(16):3088-3096. Epub 2017 Apr 7.

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cncr.30698DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544546PMC
August 2017

What We Know About Stage II and III Colon Cancer: It's Still Not Enough.

Target Oncol 2017 06;12(3):265-275

Division of Medical Oncology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Suite 3456, Los Angeles, CA, 90033, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11523-017-0494-5DOI Listing
June 2017

New perspectives for colorectal cancer.

Oncotarget 2017 Jun;8(26):41782-41783

Division of Medical Oncology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.18448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522023PMC
June 2017

Comparative effectiveness of screening strategies for colorectal cancer.

Cancer 2017 05 24;123(9):1516-1527. Epub 2017 Jan 24.

Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cncr.30518DOI Listing
May 2017

Autophagy-related polymorphisms predict hypertension in patients with metastatic colorectal cancer treated with FOLFIRI and bevacizumab: Results from TRIBE and FIRE-3 trials.

Eur J Cancer 2017 05 26;77:13-20. Epub 2017 Mar 26.

Division of Medical Oncology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90033, USA; Department of Preventive Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90033, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejca.2017.02.020DOI Listing
May 2017

What roles do colon stem cells and gap junctions play in the left and right location of origin of colorectal cancers?

J Cell Commun Signal 2017 Mar 20;11(1):79-87. Epub 2017 Feb 20.

University of California Norris Comprehensive Cancer Center, Los Angeles, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12079-017-0381-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362582PMC
March 2017

Biomarker in Colorectal Cancer.

Cancer J 2016 May-Jun;22(3):156-64

From the USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PPO.0000000000000190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955946PMC
January 2017

Metastatic Colorectal Cancer in Hispanics: Treatment Outcomes in a Treated Population.

Clin Colorectal Cancer 2016 12 31;15(4):e221-e227. Epub 2016 Mar 31.

Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA; Keck School of Medicine, University of Southern California, Los Angeles, CA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clcc.2016.03.001DOI Listing
December 2016

ESMO / ASCO Recommendations for a Global Curriculum in Medical Oncology Edition 2016.

Authors:
Christian Dittrich Michael Kosty Svetlana Jezdic Doug Pyle Rossana Berardi Jonas Bergh Nagi El-Saghir Jean-Pierre Lotz Pia Österlund Nicholas Pavlidis Gunta Purkalne Ahmad Awada Susana Banerjee Smita Bhatia Jan Bogaerts Jan Buckner Fatima Cardoso Paolo Casali Edward Chu Julia Lee Close Bertrand Coiffier Roisin Connolly Sarah Coupland Luigi De Petris Maria De Santis Elisabeth G E de Vries Don S Dizon Jennifer Duff Linda R Duska Alexandru Eniu Marc Ernstoff Enriqueta Felip Martin F Fey Jill Gilbert Nicolas Girard Andor W J M Glaudemans Priya K Gopalan Axel Grothey Stephen M Hahn Diana Hanna Christian Herold Jørn Herrstedt Krisztian Homicsko Dennie V Jones Lorenz Jost Ulrich Keilholz Saad Khan Alexander Kiss Claus-Henning Köhne Rainer Kunstfeld Heinz-Josef Lenz Stuart Lichtman Lisa Licitra Thomas Lion Saskia Litière Lifang Liu Patrick J Loehrer Merry Jennifer Markham Ben Markman Marius Mayerhoefer Johannes G Meran Olivier Michielin Elizabeth Charlotte Moser Giannis Mountzios Timothy Moynihan Torsten Nielsen Yuichiro Ohe Kjell Öberg Antonio Palumbo Fedro Alessandro Peccatori Michael Pfeilstöcker Chandrajit Raut Scot C Remick Mark Robson Piotr Rutkowski Roberto Salgado Lidia Schapira Eva Schernhammer Martin Schlumberger Hans-Joachim Schmoll Lowell Schnipper Cristiana Sessa Charles L Shapiro Julie Steele Cora N Sternberg Friedrich Stiefel Florian Strasser Roger Stupp Richard Sullivan Josep Tabernero Luzia Travado Marcel Verheij Emile Voest Everett Vokes Jamie Von Roenn Jeffrey S Weber Hans Wildiers Yosef Yarden

ESMO Open 2016 29;1(5):e000097. Epub 2016 Sep 29.

Department of General Medical Oncology , University Hospitals Leuven , Leuven , Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/esmoopen-2016-000097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070299PMC
September 2016

Molecular Pathways: Cachexia Signaling-A Targeted Approach to Cancer Treatment.

Clin Cancer Res 2016 Aug 23;22(16):3999-4004. Epub 2016 Jun 23.

Division of Medical Oncology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-16-0495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987228PMC
August 2016

CDX2 as a Prognostic Biomarker in Colon Cancer.

N Engl J Med 2016 06;374(22):2183

University of Southern California, Los Angeles, Los Angeles, CA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMc1602584DOI Listing
June 2016