Heinz Gisslinger

Heinz Gisslinger

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Heinz Gisslinger

Publications by authors named "Heinz Gisslinger"

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Splanchnic vein thromboses associated with myeloproliferative neoplasms: An international, retrospective study on 518 cases.

Authors:
Emanuela Sant'Antonio Paola Guglielmelli Lisa Pieri Massimo Primignani Maria Luigia Randi Claudia Santarossa Elisa Rumi Francisco Cervantes Federica Delaini Alessandra Carobbio Silvia Betti Elena Rossi Noa Lavi Claire N Harrison Natalia Curto-Garcia Heinz Gisslinger Bettina Gisslinger Giorgina Specchia Alessandra Ricco Nicola Vianelli Nicola Polverelli Maya Koren-Michowitz Marco Ruggeri Francois Girodon Martin Ellis Alessandra Iurlo Francesco Mannelli Lara Mannelli Benedetta Sordi Giuseppe Gaetano Loscocco Mario Cazzola Valerio De Stefano Tiziano Barbui Ayalew Tefferi Alessandro Maria Vannucchi

Am J Hematol 2020 Feb 29;95(2):156-166. Epub 2019 Nov 29.

CRIMM, Centro di Ricerca e Innovazione per le Malattie Mieloproliferative, Azienda Ospedaliera Universitaria Careggi, Florence, Italy.

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http://dx.doi.org/10.1002/ajh.25677DOI Listing
February 2020

Results from HARMONY: an open-label, multicenter, 2-arm, phase 1b, dose-finding study assessing the safety and efficacy of the oral combination of ruxolitinib and buparlisib in patients with myelofibrosis.

Authors:
Simon T Durrant Arnon Nagler Paola Guglielmelli David Lavie Philipp le Coutre Heinz Gisslinger Charles Chuah Margherita Maffioli Savita Bharathy Tuochuan Dong Monika Wroclawska Joaquin Martinez Lopez

Haematologica 2019 Dec 9;104(12):e551-e554. Epub 2019 May 9.

Hematology Department, Hospital 12 de Octubre, CNIO, Univ Complutense, CIBERONC, Madrid, Spain.

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http://dx.doi.org/10.3324/haematol.2018.209965DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959180PMC
December 2019

GDF-15 in solid vs non-solid treatment-naïve malignancies.

Authors:
Henrike Arfsten Anna Cho Claudia Freitag Markus Raderer Georg Goliasch Philipp E Bartko Raphael Wurm Guido Strunk Heinz Gisslinger Christine Marosi Gabriela Kornek Christoph Zielinski Martin Hülsmann Noemi Pavo

Eur J Clin Invest 2019 Nov 26;49(11):e13168. Epub 2019 Sep 26.

Department of Internal Medicine II, Division of Cardiology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1111/eci.13168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899906PMC
November 2019

Comments on pre-fibrotic myelofibrosis and how should it be managed.

Authors:
Tiziano Barbui Juergen Thiele Heinz Gisslinger Attilio Orazi Alessandro M Vannucchi Umberto Gianelli Christine Beham-Schmid Ayalew Tefferi

Br J Haematol 2019 Jul 7;186(2):358-360. Epub 2019 Mar 7.

Mayo Clinic, Rochester, MN, USA.

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http://doi.wiley.com/10.1111/bjh.15840
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http://dx.doi.org/10.1111/bjh.15840DOI Listing
July 2019

Mutational landscape of the transcriptome offers putative targets for immunotherapy of myeloproliferative neoplasms.

Authors:
Fiorella Schischlik Roland Jäger Felix Rosebrock Eva Hug Michael Schuster Raimund Holly Elisabeth Fuchs Jelena D Milosevic Feenstra Edith Bogner Bettina Gisslinger Martin Schalling Elisa Rumi Daniela Pietra Gottfried Fischer Ingrid Faé Loan Vulliard Jörg Menche Torsten Haferlach Manja Meggendorfer Anna Stengel Christoph Bock Mario Cazzola Heinz Gisslinger Robert Kralovics

Blood 2019 07 7;134(2):199-210. Epub 2019 May 7.

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.

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http://dx.doi.org/10.1182/blood.2019000519DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624966PMC
July 2019

EXPAND, a dose-finding study of ruxolitinib in patients with myelofibrosis and low platelet counts: 48-week follow-up analysis.

Authors:
Alessandro M Vannucchi Peter A W Te Boekhorst Claire N Harrison Guangsheng He Marianna Caramella Dietger Niederwieser Françoise Boyer-Perrard Minghui Duan Nathalie Francillard Betty Molloy Monika Wroclawska Heinz Gisslinger

Haematologica 2019 05 15;104(5):947-954. Epub 2018 Nov 15.

Department of Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Austria.

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http://www.haematologica.org/lookup/doi/10.3324/haematol.201
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http://dx.doi.org/10.3324/haematol.2018.204602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518918PMC
May 2019

A phase III randomized, multicentre, double blind, active controlled trial to compare the efficacy and safety of two different anagrelide formulations in patients with essential thrombocythaemia - the TEAM-ET 2·0 trial.

Authors:
Heinz Gisslinger Veronika Buxhofer-Ausch Juri Hodisch Atanas Radinoff Elena Karyagina Slawomira Kyrcz-Krzemień Kudrat Abdulkadyrov Rolandas Gerbutavicius Anait Melikyan Sonja Burgstaller Marek Hus Janusz Kłoczko Vera Yablokova Nikolay Tzvetkov Malgorzata Całbecka Tatyana Shneyder Krzysztof Warzocha Mindaugas Jurgutis Kamil Kaplanov Bernd Jilma Christian Schoergenhofer Christoph Klade

Br J Haematol 2019 May 28;185(4):691-700. Epub 2019 Mar 28.

AOP Orphan Pharmaceuticals AG, Vienna, Austria.

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http://dx.doi.org/10.1111/bjh.15824DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594023PMC
May 2019

CDK6 coordinates mutant MPN via NF-κB and apoptotic networks.

Authors:
Iris Z Uras Barbara Maurer Harini Nivarthi Philipp Jodl Karoline Kollmann Michaela Prchal-Murphy Jelena D Milosevic Feenstra Markus Zojer Sabine Lagger Reinhard Grausenburger Beatrice Grabner Raimund Holly Anoop Kavirayani Christoph Bock Heinz Gisslinger Peter Valent Robert Kralovics Veronika Sexl

Blood 2019 04 11;133(15):1677-1690. Epub 2019 Jan 11.

Institute of Pharmacology and Toxicology, University of Veterinary Medicine, Vienna, Austria.

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http://dx.doi.org/10.1182/blood-2018-08-872648DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543514PMC
April 2019

The circulating form of neprilysin is not a general biomarker for overall survival in treatment-naïve cancer patients.

Authors:
Noemi Pavo Henrike Arfsten Anna Cho Georg Goliasch Philipp E Bartko Raphael Wurm Claudia Freitag Heinz Gisslinger Gabriela Kornek Guido Strunk Markus Raderer Christoph Zielinski Martin Hülsmann

Sci Rep 2019 Feb 22;9(1):2554. Epub 2019 Feb 22.

Department of Internal Medicine II, Clinical Division of Cardiology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1038/s41598-019-38867-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385211PMC
February 2019

Correction to: Ruxolitinib therapy formyelofibrosis in Austria : Consensus on therapy management.

Authors:
Maria-Theresa Krauth Sonja Burgstaller Veronika Buxhofer-Ausch Günther Gastl Klaus Geissler Felix Keil Peter Krippl Thomas Melchardt Andreas Petzer Holger Rumpold Thamer Sliwa Stefan Wöhrer Albert Wölfler Heinz Gisslinger

Wien Klin Wochenschr 2019 01;131(1-2):47

Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University Vienna, Vienna, Austria.

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http://link.springer.com/10.1007/s00508-018-1428-7
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http://dx.doi.org/10.1007/s00508-018-1428-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828473PMC
January 2019

Response to aspirin therapy in patients with myeloproliferative neoplasms depends on the platelet count.

Authors:
Thomas Gremmel Bettina Gisslinger Heinz Gisslinger Simon Panzer

Transl Res 2018 10 13;200:35-42. Epub 2018 Jun 13.

Department of Blood Group Serology and Transfusion Medicine, Medical University of Vienna, Vienna, Austria.

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https://linkinghub.elsevier.com/retrieve/pii/S19315244183009
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http://dx.doi.org/10.1016/j.trsl.2018.05.009DOI Listing
October 2018

Ropeginterferon alpha-2b targets JAK2V617F-positive polycythemia vera cells in vitro and in vivo.

Authors:
Emmanuelle Verger Juliette Soret-Dulphy Nabih Maslah Lydia Roy Jerome Rey Zineb Ghrieb Robert Kralovics Heinz Gisslinger Barbara Grohmann-Izay Christoph Klade Christine Chomienne Stéphane Giraudier Bruno Cassinat Jean-Jacques Kiladjian

Blood Cancer J 2018 10 4;8(10):94. Epub 2018 Oct 4.

Centre d'Investigations Cliniques, Hôpital Saint-Louis (AP-HP), Paris, France.

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http://www.nature.com/articles/s41408-018-0133-0
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http://dx.doi.org/10.1038/s41408-018-0133-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172224PMC
October 2018

Impact of renal impairment on outcomes after autologous stem cell transplantation in multiple myeloma: a multi-center, retrospective cohort study.

Authors:
Marlies Antlanger Tobias Dust Thomas Reiter Alexandra Böhm Wolfgang W Lamm Max Gornicec Ella Willenbacher David Nachbaur Roman Weger Werner Rabitsch Susanne Rasoul-Rockenschaub Nina Worel Daniel Lechner Hildegard Greinix Felix Keil Heinz Gisslinger Hermine Agis Maria-Theresa Krauth

BMC Cancer 2018 Oct 20;18(1):1008. Epub 2018 Oct 20.

Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.

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https://bmccancer.biomedcentral.com/articles/10.1186/s12885-
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http://dx.doi.org/10.1186/s12885-018-4926-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195957PMC
October 2018

The WHO diagnostic criteria for polycythemia vera-role of red cell mass versus hemoglobin/hematocrit level and morphology.

Authors:
Ljubomir Jakovic Mirjana Gotic Heinz Gisslinger Ivan Soldatovic Dijana Sefer Mila Tirnanic Danijela Lekovic Maja Perunicic Jovanovic Martin Schalling Bettina Gisslinger Christine Beham-Schmid Ingrid Simonitsch-Klupp Jürgen Thiele

Ann Hematol 2018 Sep 1;97(9):1581-1590. Epub 2018 May 1.

Institute of Pathology, University of Cologne, Kerpener Str. 62, 50924, Cologne, Germany.

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http://link.springer.com/10.1007/s00277-018-3344-3
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http://dx.doi.org/10.1007/s00277-018-3344-3DOI Listing
September 2018

Austrian recommendations for the management of polycythemia vera.

Authors:
Sonja Burgstaller Veronika Buxhofer-Ausch Thamer Sliwa Christine Beham-Schmid Günther Gastl Klaus Geissler Thomas Melchardt Maria Krauth Peter Krippl Andreas Petzer Holger Rumpold Albert Wölfler Heinz Gisslinger

Wien Klin Wochenschr 2018 Sep 19;130(17-18):535-542. Epub 2018 Jul 19.

Department of Internal Medicine I, Division of Hematology and Blood Coagulation, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1007/s00508-018-1359-3DOI Listing
September 2018

Ruxolitinib therapy for myelofibrosis in Austria : Consensus on therapy management.

Authors:
Maria-Theresa Krauth Sonja Burgstaller Veronika Buxhofer-Ausch Günther Gastl Klaus Geissler Felix Keil Peter Krippl Thomas Melchardt Andreas Petzer Holger Rumpold Thamer Sliwa Stefan Wöhrer Albert Wölfler Heinz Gisslinger

Wien Klin Wochenschr 2018 Sep 24;130(17-18):495-504. Epub 2018 Jul 24.

Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University Vienna, Vienna, Austria.

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http://dx.doi.org/10.1007/s00508-018-1365-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132876PMC
September 2018

Aggressive B-cell lymphomas in patients with myelofibrosis receiving JAK1/2 inhibitor therapy.

Authors:
Edit Porpaczy Sabrina Tripolt Andrea Hoelbl-Kovacic Bettina Gisslinger Zsuzsanna Bago-Horvath Emilio Casanova-Hevia Emmanuelle Clappier Thomas Decker Sabine Fajmann Daniela A Fux Georg Greiner Sinan Gueltekin Gerwin Heller Harald Herkner Gregor Hoermann Jean-Jacques Kiladjian Thomas Kolbe Christoph Kornauth Maria-Theresa Krauth Robert Kralovics Leonhard Muellauer Mathias Mueller Michaela Prchal-Murphy Eva Maria Putz Emmanuel Raffoux Ana-Iris Schiefer Klaus Schmetterer Christine Schneckenleithner Ingrid Simonitsch-Klupp Cathrin Skrabs Wolfgang R Sperr Philipp Bernhard Staber Birgit Strobl Peter Valent Ulrich Jaeger Heinz Gisslinger Veronika Sexl

Blood 2018 08 14;132(7):694-706. Epub 2018 Jun 14.

Institute of Pharmacology and Toxicology, Department for Biomedical Sciences, University of Veterinary Medicine Vienna, Vienna, Austria.

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http://dx.doi.org/10.1182/blood-2017-10-810739DOI Listing
August 2018

Recommendations for the diagnosis and treatment of patients with polycythaemia vera.

Authors:
Antónia Hatalova Jiri Schwarz Mirjana Gotic Miroslav Penka Mikulas Hrubisko Rajko Kusec Miklós Egyed Martin Griesshammer Maria Podolak-Dawidziak Andrzej Hellmann Sergiy Klymenko Emilia Niculescu-Mizil Petro E Petrides Sebastian Grosicki Matjaz Sever Nathan Cantoni Jürgen Thiele Dominik Wolf Heinz Gisslinger

Eur J Haematol 2018 Jul 30. Epub 2018 Jul 30.

Division of Hematology and Blood Coagulation, Department of Internal Medicine I, Medical University of Vienna Hospital, Vienna, Austria.

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http://dx.doi.org/10.1111/ejh.13156DOI Listing
July 2018

Impact of white blood cells on thrombotic risk in patients with optimized platelet count in essential thrombocythemia.

Authors:
Veronika Buxhofer-Ausch Michael Steurer Siegfried Sormann Ernst Schloegl Wolfgang Schimetta Bettina Gisslinger Martin Schalling Maria Theresa Krauth Jürgen Thiele Reinhard Ruckser Günther Gastl Heinz Gisslinger

Eur J Haematol 2018 Mar 30. Epub 2018 Mar 30.

Division of Hematology and Blood Coagulation, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria.

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http://doi.wiley.com/10.1111/ejh.13070
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http://dx.doi.org/10.1111/ejh.13070DOI Listing
March 2018

The 2016 WHO classification and diagnostic criteria for myeloproliferative neoplasms: document summary and in-depth discussion.

Authors:
Tiziano Barbui Jürgen Thiele Heinz Gisslinger Hans Michael Kvasnicka Alessandro M Vannucchi Paola Guglielmelli Attilio Orazi Ayalew Tefferi

Blood Cancer J 2018 02 9;8(2):15. Epub 2018 Feb 9.

Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1038/s41408-018-0054-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807384PMC
February 2018

Image-based ex-vivo drug screening for patients with aggressive haematological malignancies: interim results from a single-arm, open-label, pilot study.

Authors:
Berend Snijder Gregory I Vladimer Nikolaus Krall Katsuhiro Miura Ann-Sofie Schmolke Christoph Kornauth Oscar Lopez de la Fuente Hye-Soo Choi Emiel van der Kouwe Sinan Gültekin Lukas Kazianka Johannes W Bigenzahn Gregor Hoermann Nicole Prutsch Olaf Merkel Anna Ringler Monika Sabler Georg Jeryczynski Marius E Mayerhoefer Ingrid Simonitsch-Klupp Katharina Ocko Franz Felberbauer Leonhard Müllauer Gerald W Prager Belgin Korkmaz Lukas Kenner Wolfgang R Sperr Robert Kralovics Heinz Gisslinger Peter Valent Stefan Kubicek Ulrich Jäger Philipp B Staber Giulio Superti-Furga

Lancet Haematol 2017 Dec 15;4(12):e595-e606. Epub 2017 Nov 15.

CeMM Research Center for Molecular Medicine, Vienna, Austria; Center for Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/S2352-3026(17)30208-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719985PMC
December 2017

Essential thrombocythemia vs. pre-fibrotic/early primary myelofibrosis: discrimination by laboratory and clinical data.

Authors:
Martin Schalling Andreas Gleiss Bettina Gisslinger Albert Wölfler Veronika Buxhofer-Ausch Georg Jeryczynski Maria-Theresa Krauth Ingrid Simonitsch-Klupp Christine Beham-Schmid Jürgen Thiele Heinz Gisslinger

Blood Cancer J 2017 12 13;7(12):643. Epub 2017 Dec 13.

Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1038/s41408-017-0006-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802530PMC
December 2017

Impact of white blood cell counts at diagnosis and during follow-up in patients with essential thrombocythaemia and prefibrotic primary myelofibrosis.

Authors:
Veronika Buxhofer-Ausch Bettina Gisslinger Martin Schalling Andreas Gleiss Ana-Iris Schiefer Leonhard Müllauer Jürgen Thiele Robert Kralovics Heinz Gisslinger

Br J Haematol 2017 10 19;179(1):166-169. Epub 2016 Jul 19.

Division of Haematology and Blood Coagulation, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1111/bjh.14202DOI Listing
October 2017

Subclinical involvement of the liver is associated with prognosis in treatment naïve cancer patients.

Authors:
Noemi Pavo Markus Raderer Georg Goliasch Raphael Wurm Guido Strunk Anna Cho Johannes F Novak Heinz Gisslinger Günther G Steger Michael Hejna Wolfgang Köstler Sabine Zöchbauer-Müller Christine Marosi Gabriela Kornek Leo Auerbach Sven Thorben Schneider Bernhard Parschalk Werner Scheithauer Robert Pirker Barbara Kiesewetter Richard Pacher Christoph Zielinski Martin Hülsmann

Oncotarget 2017 Oct 16;8(46):81250-81260. Epub 2017 Apr 16.

Department of Internal Medicine II, Division of Cardiology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.18632/oncotarget.17131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655279PMC
October 2017

Pre-fibrotic/early primary myelofibrosis vs. WHO-defined essential thrombocythemia: The impact of minor clinical diagnostic criteria on the outcome of the disease.

Authors:
Georg Jeryczynski Jürgen Thiele Bettina Gisslinger Albert Wölfler Martin Schalling Andreas Gleiß Sonja Burgstaller Veronika Buxhofer-Ausch Thamer Sliwa Ernst Schlögl Klaus Geissler Maria-Theresa Krauth Alexander Nader Michael Vesely Ingrid Simonitsch-Klupp Leonhard Müllauer Christine Beham-Schmid Heinz Gisslinger

Am J Hematol 2017 Sep 9;92(9):885-891. Epub 2017 Jun 9.

Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1002/ajh.24788DOI Listing
September 2017

Pre-PMF emerging as important subgroup of MPN.

Authors:
Heinz Gisslinger

Blood 2017 06;129(24):3142-3144

MEDICAL UNIVERSITY OF VIENNA.

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http://dx.doi.org/10.1182/blood-2017-04-777805DOI Listing
June 2017

Austrian recommendations for the management of primary myelofibrosis, post-polycythemia vera myelofibrosis and post-essential thrombocythemia myelofibrosis: an expert statement.

Authors:
Thamer Sliwa Christine Beham-Schmid Sonja Burgstaller Veronika Buxhofer-Ausch Günther Gastl Klaus Geissler Maria Krauth Peter Krippl Alois Lang Andreas Petzer Stefan Wöhrer Albert Wölfler Heinz Gisslinger

Wien Klin Wochenschr 2017 May 13;129(9-10):293-302. Epub 2016 Dec 13.

Department of Internal Medicine I, Division of Hematology and Blood Coagulation, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1007/s00508-016-1120-8DOI Listing
May 2017

Diagnostic impact of the 2016 revised who criteria for polycythemia vera.

Authors:
Tiziano Barbui Juergen Thiele Heinz Gisslinger Alessandra Carobbio Alessandro M Vannucchi Ayalew Tefferi

Am J Hematol 2017 05 4;92(5):417-419. Epub 2017 Mar 4.

Hematology division, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1002/ajh.24684DOI Listing
May 2017

The effect of arterial hypertension on thrombosis in low-risk polycythemia vera.

Authors:
Tiziano Barbui Alessandro M Vannucchi Alessandra Carobbio Elisa Rumi Guido Finazzi Heinz Gisslinger Marco Ruggeri Maria Luigia Randi Mario Cazzola Alessandro Rambaldi Bettina Gisslinger Lisa Pieri Juergen Thiele Animesh Pardanani Ayalew Tefferi

Am J Hematol 2017 Jan;92(1):E5-E6

Division of Hematology Department of Medicine, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1002/ajh.24583DOI Listing
January 2017

Influence of platelet and white blood cell counts on major thrombosis - analysis from a patient registry in essential thrombocythemia.

Authors:
Veronika Buxhofer-Ausch Michael Steurer Siegfried Sormann Ernst Schloegl Wolfgang Schimetta Bettina Gisslinger Reinhard Ruckser Günther Gastl Heinz Gisslinger

Eur J Haematol 2016 Dec 23;97(6):511-516. Epub 2016 May 23.

Division of Hematology and Blood Coagulation, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1111/ejh.12759DOI Listing
December 2016

In vitro and in vivo effects of JAK2 inhibition in chronic myelomonocytic leukemia.

Authors:
Klaus Geissler Eva Jäger Agnes Barna Thamer Sliwa Paul Knöbl Ilse Schwarzinger Heinz Gisslinger Peter Valent

Eur J Haematol 2016 Dec 15;97(6):562-567. Epub 2016 Jun 15.

Division of Hematology and Hemostaseology, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1111/ejh.12773DOI Listing
December 2016

Is ruxolitinib a potentially useful drug in hematological malignancies with RAS pathway hyperactivation?

Authors:
Klaus Geissler Eva Jäger Agnes Barna Thamer Sliwa Paul Knöbl Ilse Schwarzinger Heinz Gisslinger Peter Valent

Haematologica 2016 12;101(12):e492

Division of Hematology and Hemostaseology, Department of Internal Medicine I, Medical University of Vienna, Austria.

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http://dx.doi.org/10.3324/haematol.2016.156448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479601PMC
December 2016

Updated Outcomes and Impact of Age With Lenalidomide and Low-Dose Dexamethasone or Melphalan, Prednisone, and Thalidomide in the Randomized, Phase III FIRST Trial.

Authors:
Cyrille Hulin Andrew Belch Chaim Shustik Maria Teresa Petrucci Ulrich Dührsen Jin Lu Kevin Song Philippe Rodon Brigitte Pégourié Laurent Garderet Hannah Hunter Isabelle Azais Richard Eek Heinz Gisslinger Margaret Macro Shaker Dakhil Cristina Goncalves Richard LeBlanc Ken Romeril Bruno Royer Chantal Doyen Xavier Leleu Fritz Offner Nicolas Leupin Vanessa Houck Guang Chen Annette Ervin-Haynes Meletios A Dimopoulos Thierry Facon

J Clin Oncol 2016 10;34(30):3609-3617

Cyrille Hulin, Bordeaux Hospital University Center, Bourdeaux; Philippe Rodon, Centre Hospitalier de Périgueux, Périgueux; Brigitte Pégourié, Centre Hospitalier Regional Universitaire, Grenoble; Laurent Garderet, Centre Hospitalier Universitaire (CHU) Hôpital St-Antoine, Paris; Isabelle Azais, CHU Institut National de la Santé et de la Recherche Médicale (INSERM); Xavier Leleu, Hôpital de la Milétrie, CHU INSERM, Poitiers; Margaret Macro, CHU de Caen, Caen; Bruno Royer, University Hospital, Amiens; Thierry Facon, Hôpital Claude Huriez, Centre Hospitalier Régional Universitaire de Lille, Lille, France; Andrew Belch, Cross Cancer Institute, Edmonton, Alberta; Chaim Shustik, Royal Victoria Hospital; Richard LeBlanc, Hôpital Maisonneuve-Rosemont, Montreal, Quebec; Kevin Song, Vancouver General Hospital, Vancouver, British Columbia, Canada; Maria Teresa Petrucci, Azienda Policlinico Umberto I, University La Sapienza, Rome, Italy; Ulrich Dührsen, University Hospital of Essen, West German Cancer Center, Essen, Germany; Jin Lu, Peking University Institute of Hematology, People's Hospital, Beijing, China; Hannah Hunter, Derriford Hospital, Plymouth, United Kingdom; Richard Eek, Border Medical Oncology, Wodonga, Victoria, Australia; Heinz Gisslinger, Medizinische Universität Wien, Vienna, Austria; Shaker Dakhil, Cancer Center of Kansas, Wichita, KS; Cristina Goncalves, Hospital de Santo Antonio-Porto, Porto, Portugal; Ken Romeril, Wellington Hospital, Wellington, New Zealand; Chantal Doyen, Université Catholique de Louvain (UCL), CHU UCL Namur, Yvoir; Fritz Offner, Universitair Ziekenhuis Gent, Ghent, Belgium; Nicolas Leupin, Celgene International, Boudry, Switzerland; Vanessa Houck, Guang Chen, and Annette Ervin-Haynes, Celgene, Summit, NJ; and Meletios A. Dimopoulos, National and Kapodistrian University of Athens School of Medicine, Athens, Greece.

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http://dx.doi.org/10.1200/JCO.2016.66.7295DOI Listing
October 2016

[In Process Citation].

Authors:
Heinz Gisslinger Miroslav Penka

Leuk Res 2016 05 26;44 Suppl 1. Epub 2016 Apr 26.

Deputy Chair of CEMPO (Central European Myeloproliferative Neoplasm Organization).

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http://dx.doi.org/10.1016/S0145-2126(16)30070-4DOI Listing
May 2016

Whole-exome sequencing identifies novel MPL and JAK2 mutations in triple-negative myeloproliferative neoplasms.

Authors:
Jelena D Milosevic Feenstra Harini Nivarthi Heinz Gisslinger Emilie Leroy Elisa Rumi Ilyas Chachoua Klaudia Bagienski Blanka Kubesova Daniela Pietra Bettina Gisslinger Chiara Milanesi Roland Jäger Doris Chen Tiina Berg Martin Schalling Michael Schuster Christoph Bock Stefan N Constantinescu Mario Cazzola Robert Kralovics

Blood 2016 Jan 30;127(3):325-32. Epub 2015 Sep 30.

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria; Department of Internal Medicine I, Division of Hematology and Blood Coagulation, Medical University of Vienna, Vienna, Austria;

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752213PMC
January 2016

Germline RBBP6 mutations in familial myeloproliferative neoplasms.

Authors:
Ashot S Harutyunyan Roberto Giambruno Christian Krendl Alexey Stukalov Thorsten Klampfl Tiina Berg Doris Chen Jelena D Milosevic Feenstra Roland Jäger Bettina Gisslinger Heinz Gisslinger Elisa Rumi Francesco Passamonti Daniela Pietra André C Müller Katja Parapatics Florian P Breitwieser Richard Herrmann Jacques Colinge Keiryn L Bennett Giulio Superti-Furga Mario Cazzola Emma Hammond Robert Kralovics

Blood 2016 Jan 16;127(3):362-5. Epub 2015 Nov 16.

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria; Department of Internal Medicine I, Division of Hematology and Blood Coagulation, Medical University of Vienna, Vienna, Austria;

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043418PMC
January 2016

Long non-coding RNAs display higher natural expression variation than protein-coding genes in healthy humans.

Authors:
Aleksandra E Kornienko Christoph P Dotter Philipp M Guenzl Heinz Gisslinger Bettina Gisslinger Ciara Cleary Robert Kralovics Florian M Pauler Denise P Barlow

Genome Biol 2016 Jan 29;17:14. Epub 2016 Jan 29.

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 14, AKH BT 25.3, 1090, Vienna, Austria.

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January 2016

Outcome in Multiple Myeloma Patients Eligible for Stem Cell Transplantation: A Single-Center Experience.

Authors:
Wolfgang Lamm Philipp Wohlfarth Marija Bojic Christian Schörgenhofer Johannes Drach Heinz Gisslinger Nina Worel Ana Schiefer Axel Schulenburg Hermine Agis Peter Kalhs Hildegard T Greinix Peter Schellongowski Werner Rabitsch

Oncology 2015 23;89(4):196-204. Epub 2015 Jul 23.

Clinical Division of Oncology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1159/000437055DOI Listing
December 2015

Iron metabolism and iron supplementation in cancer patients.

Authors:
Heinz Ludwig Rayko Evstatiev Gabriela Kornek Matti Aapro Thomas Bauernhofer Veronika Buxhofer-Ausch Michael Fridrik Dietmar Geissler Klaus Geissler Heinz Gisslinger Elisabeth Koller Gerhard Kopetzky Alois Lang Holger Rumpold Michael Steurer Houman Kamali Hartmut Link

Wien Klin Wochenschr 2015 Dec 15;127(23-24):907-19. Epub 2015 Sep 15.

Medizinische Klinik I, Westpfalz-Klinikum, Kaiserslautern, Germany.

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http://link.springer.com/10.1007/s00508-015-0842-3
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679104PMC
December 2015

Cardiovascular biomarkers in patients with cancer and their association with all-cause mortality.

Authors:
Noemi Pavo Markus Raderer Martin Hülsmann Stephanie Neuhold Christopher Adlbrecht Guido Strunk Georg Goliasch Heinz Gisslinger Günther G Steger Michael Hejna Wolfgang Köstler Sabine Zöchbauer-Müller Christine Marosi Gabriela Kornek Leo Auerbach Sven Schneider Bernhard Parschalk Werner Scheithauer Robert Pirker Johannes Drach Christoph Zielinski Richard Pacher

Heart 2015 Dec 28;101(23):1874-80. Epub 2015 Sep 28.

Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna, Vienna, Austria.

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December 2015

Erratum to: Iron metabolism and iron supplementation in cancer patients.

Authors:
Heinz Ludwig Rayko Evstatiev Gabriela Kornek Matti Aapro Thomas Bauernhofer Veronika Buxhofer-Ausch Michael Fridrik Dietmar Geissler Klaus Geissler Heinz Gisslinger Elisabeth Koller Gerhard Kopetzky Alois Lang Holger Rumpold Michael Steurer Houman Kamali Hartmut Link

Wien Klin Wochenschr 2015 Dec;127(23-24):920-1

Medizinische Klinik I, Westpfalz-Klinikum, Kaiserslautern, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713978PMC
December 2015

Ropeginterferon alfa-2b, a novel IFNα-2b, induces high response rates with low toxicity in patients with polycythemia vera.

Authors:
Heinz Gisslinger Oleh Zagrijtschuk Veronika Buxhofer-Ausch Josef Thaler Ernst Schloegl Guenther A Gastl Dominik Wolf Robert Kralovics Bettina Gisslinger Karin Strecker Alexander Egle Thomas Melchardt Sonja Burgstaller Ella Willenbacher Martin Schalling Nicole C Them Pavla Kadlecova Christoph Klade Richard Greil

Blood 2015 Oct 10;126(15):1762-9. Epub 2015 Aug 10.

Laboratory for Immunological and Molecular Cancer Research, Department of Internal Medicine III with Hematology, Medical Oncology, Hemostaseology, Infectious Diseases, Rheumatology, Oncologic Center, Paracelsus Medical University, Salzburg, Austria; and.

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http://dx.doi.org/10.1182/blood-2015-04-637280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608390PMC
October 2015

Interleukin-10 inhibits autonomous myelopoiesis in patients with myelofibrosis.

Authors:
Klaus Geissler Eva Jäger Leopold Öhler Heinz Gisslinger Ulrich Jäger Klaus Lechner

Eur J Haematol 2015 Sep 7;95(3):239-43. Epub 2015 Jan 7.

Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1111/ejh.12486DOI Listing
September 2015

The use of erythropoiesis-stimulating agents with ruxolitinib in patients with myelofibrosis in COMFORT-II: an open-label, phase 3 study assessing efficacy and safety of ruxolitinib versus best available therapy in the treatment of myelofibrosis.

Authors:
Mary Frances McMullin Claire N Harrison Dietger Niederwieser Hilde Demuynck Nadja Jäkel Prashanth Gopalakrishna Mari McQuitty Viktoriya Stalbovskaya Christian Recher Koen Theunissen Heinz Gisslinger Jean-Jacques Kiladjian Haifa-Kathrin Al-Ali

Exp Hematol Oncol 2015 15;4:26. Epub 2015 Sep 15.

University of Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.1186/s40164-015-0021-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570722PMC
September 2015

Current and future treatment options for polycythemia vera.

Authors:
Martin Griesshammer Heinz Gisslinger Ruben Mesa

Ann Hematol 2015 Jun 2;94(6):901-10. Epub 2015 Apr 2.

Johannes Wesling Academic Medical Center, Minden, Germany,

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http://dx.doi.org/10.1007/s00277-015-2357-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420843PMC
June 2015

Tetraspanin CD9 participates in dysmegakaryopoiesis and stromal interactions in primary myelofibrosis.

Authors:
Christophe Desterke Christophe Martinaud Bernadette Guerton Lisa Pieri Costanza Bogani Denis Clay Frederic Torossian Jean-Jacques Lataillade Hans C Hasselbach Heinz Gisslinger Jean-Loup Demory Brigitte Dupriez Claude Boucheix Eric Rubinstein Sophie Amsellem Alessandro M Vannucchi Marie-Caroline Le Bousse-Kerdilès

Haematologica 2015 Jun 3;100(6):757-67. Epub 2015 Apr 3.

INSERM UMR-S1197, Paul Brousse Hospital, Paris-Sud University, Villejuif, France INSERM UMS33, Paul Brousse Hospital, Paris-Sud University, Villejuif, France French Intergroup on Myeloproliferative Neoplasms (FIM), France

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http://dx.doi.org/10.3324/haematol.2014.118497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450621PMC
June 2015

Patterns of presentation and thrombosis outcome in patients with polycythemia vera strictly defined by WHO-criteria and stratified by calendar period of diagnosis.

Authors:
Tiziano Barbui Alessandro M Vannucchi Alessandra Carobbio Jurgen Thiele Elisa Rumi Heinz Gisslinger Francesco Rodeghiero Maria Luigia Randi Alessandro Rambaldi Lisa Pieri Animesh Pardanani Francesco Passamonti Guido Finazzi Ayalew Tefferi

Am J Hematol 2015 May 27;90(5):434-7. Epub 2015 Feb 27.

Research Foundation Papa Giovanni XXIII Hospital, Bergamo, Italy.

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May 2015

Molecular responses and chromosomal aberrations in patients with polycythemia vera treated with peg-proline-interferon alpha-2b.

Authors:
Nicole C C Them Klaudia Bagienski Tiina Berg Bettina Gisslinger Martin Schalling Doris Chen Veronika Buxhofer-Ausch Josef Thaler Ernst Schloegl Guenther A Gastl Dominik Wolf Karin Strecker Alexander Egle Thomas Melchardt Sonja Burgstaller Ella Willenbacher Oleh Zagrijtschuk Christoph Klade Richard Greil Heinz Gisslinger Robert Kralovics

Am J Hematol 2015 Apr 2;90(4):288-94. Epub 2015 Mar 2.

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.

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http://dx.doi.org/10.1002/ajh.23928DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657499PMC
April 2015

Genetic variation at MECOM, TERT, JAK2 and HBS1L-MYB predisposes to myeloproliferative neoplasms.

Authors:
William Tapper Amy V Jones Robert Kralovics Ashot S Harutyunyan Katerina Zoi William Leung Anna L Godfrey Paola Guglielmelli Alison Callaway Daniel Ward Paula Aranaz Helen E White Katherine Waghorn Feng Lin Andrew Chase E Joanna Baxter Cathy Maclean Jyoti Nangalia Edwin Chen Paul Evans Michael Short Andrew Jack Louise Wallis David Oscier Andrew S Duncombe Anna Schuh Adam J Mead Michael Griffiths Joanne Ewing Rosemary E Gale Susanne Schnittger Torsten Haferlach Frank Stegelmann Konstanze Döhner Harald Grallert Konstantin Strauch Toshiko Tanaka Stefania Bandinelli Andreas Giannopoulos Lisa Pieri Carmela Mannarelli Heinz Gisslinger Giovanni Barosi Mario Cazzola Andreas Reiter Claire Harrison Peter Campbell Anthony R Green Alessandro Vannucchi Nicholas C P Cross

Nat Commun 2015 Apr 7;6:6691. Epub 2015 Apr 7.

1] Faculty of Medicine, University of Southampton, Southampton SO16 6YD, UK [2] Wessex Regional Genetics Laboratory, Salisbury District Hospital, Salisbury SP2 8BJ, UK.

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http://dx.doi.org/10.1038/ncomms7691DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396373PMC
April 2015

Circulating hematopoietic progenitor cells in essential thrombocythemia versus prefibrotic/early primary myelofibrosis.

Authors:
Klaus Geissler Eva Jäger Bettina Gisslinger Juergen Thiele Ilse Schwarzinger Heinz Gisslinger

Am J Hematol 2014 Dec 27;89(12):1157-8. Epub 2014 Aug 27.

5th Department of Internal Medicine - Oncology/Hematology, Hospital Hietzing, Vienna, Austria; Ludwig Boltzmann Institute for Clinical Oncology, Vienna, Austria.

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http://dx.doi.org/10.1002/ajh.23829DOI Listing
December 2014

In contemporary patients with polycythemia vera, rates of thrombosis and risk factors delineate a new clinical epidemiology.

Authors:
Tiziano Barbui Alessandra Carobbio Elisa Rumi Guido Finazzi Heinz Gisslinger Francesco Rodeghiero Maria Luigia Randi Alessandro Rambaldi Bettina Gisslinger Lisa Pieri Irene Bertozzi Ilaria Casetti Animesh Pardanani Francesco Passamonti Alessandro M Vannucchi Ayalew Tefferi

Blood 2014 Nov;124(19):3021-3

Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1182/blood-2014-07-591610DOI Listing
November 2014

Decanucleotide insertion polymorphism of F7 significantly influences the risk of thrombosis in patients with essential thrombocythemia.

Authors:
Veronika Buxhofer-Ausch Damla Olcaydu Bettina Gisslinger Martin Schalling Sophie Frantal Jürgen Thiele Leonhard Müllauer Hans-Michael Kvasnicka Herbert Watzke Robert Kralovics Heinz Gisslinger

Eur J Haematol 2014 Aug 23;93(2):103-11. Epub 2014 Apr 23.

Division of Hematology and Blood Coagulation, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1111/ejh.12307DOI Listing
August 2014

Complex patterns of chromosome 11 aberrations in myeloid malignancies target CBL, MLL, DDB1 and LMO2.

Authors:
Thorsten Klampfl Jelena D Milosevic Ana Puda Andreas Schönegger Klaudia Bagienski Tiina Berg Ashot S Harutyunyan Bettina Gisslinger Elisa Rumi Luca Malcovati Daniela Pietra Chiara Elena Matteo Giovanni Della Porta Lisa Pieri Paola Guglielmelli Christoph Bock Michael Doubek Dana Dvorakova Nada Suvajdzic Dragica Tomin Natasa Tosic Zdenek Racil Michael Steurer Sonja Pavlovic Alessandro M Vannucchi Mario Cazzola Heinz Gisslinger Robert Kralovics

PLoS One 2013 16;8(10):e77819. Epub 2013 Oct 16.

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797696PMC
June 2014

Restoration of response to ruxolitinib upon brief withdrawal in two patients with myelofibrosis.

Authors:
Heinz Gisslinger Martin Schalling Bettina Gisslinger Cathrin Skrabs Leonhard Müllauer Robert Kralovics

Am J Hematol 2014 Mar;89(3):344-6

Department of Hematology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1002/ajh.23637DOI Listing
March 2014

Impact of ruxolitinib on the natural history of primary myelofibrosis: a comparison of the DIPSS and the COMFORT-2 cohorts.

Authors:
Francesco Passamonti Margherita Maffioli Francisco Cervantes Alessandro Maria Vannucchi Enrica Morra Tiziano Barbui Domenica Caramazza Lisa Pieri Elisa Rumi Heinz Gisslinger Laurent Knoops Jean Jaques Kiladjian Barbara Mora Norbert Hollaender Cristiana Pascutto Claire Harrison Mario Cazzola

Blood 2014 Mar 17;123(12):1833-5. Epub 2014 Jan 17.

Division of Hematology, Department of Medicine, University Hospital Ospedale di Circolo e Fondazione Macchi, Varese, Italy;

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March 2014

Comparison of placebo and best available therapy for the treatment of myelofibrosis in the phase 3 COMFORT studies.

Authors:
Ruben A Mesa Jean-Jacques Kiladjian Srdan Verstovsek Haifa Kathrin Al-Ali Jason Gotlib Heinz Gisslinger Richard Levy Andres Siulnik Vikas Gupta Mahmudul Khan John F DiPersio Mari McQuitty John V Catalano Deborah S Hunter Laurent Knoops Michael Deininger Francisco Cervantes Carole Miller Alessandro M Vannucchi Richard T Silver Tiziano Barbui Moshe Talpaz Giovanni Barosi Elliott F Winton Estella Mendeson Jimmie H Harvey Murat O Arcasoy Elizabeth Hexner Roger M Lyons Ronald Paquette Azra Raza William Sun Victor Sandor Hagop M Kantarjian Claire Harrison

Haematologica 2014 Feb 2;99(2):292-8. Epub 2013 Aug 2.

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http://dx.doi.org/10.3324/haematol.2013.087650DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912959PMC
February 2014

Masked polycythemia vera diagnosed according to WHO and BCSH classification.

Authors:
Tiziano Barbui Jürgen Thiele Alessandra Carobbio Heinz Gisslinger Guido Finazzi Elisa Rumi Maria Luigia Randi Alessandro M Vannucchi Bettina Gisslinger Leonhard Müllauer Marco Ruggeri Alessandro Rambaldi Ayalew Tefferi

Am J Hematol 2014 Feb;89(2):199-202

Papa Giovanni XXIII Hospital, Bergamo, Italy.

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http://doi.wiley.com/10.1002/ajh.23617
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February 2014

Masked polycythemia vera (mPV): results of an international study.

Authors:
Tiziano Barbui Jürgen Thiele Heinz Gisslinger Guido Finazzi Alessandra Carobbio Elisa Rumi Maria Luigia Randi Irene Bertozzi Alessandro M Vannucchi Lisa Pieri Valentina Carrai Bettina Gisslinger Leonhard Müllauer Marco Ruggeri Alessandro Rambaldi Ayalew Tefferi

Am J Hematol 2014 01 19;89(1):52-4. Epub 2013 Sep 19.

Papa Giovanni XXIII Hospital, Bergamo, Italy.

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http://dx.doi.org/10.1002/ajh.23585DOI Listing
January 2014

High spontaneous granulocyte/macrophage-colony formation in patients with myelofibrosis.

Authors:
Verena Hauer Eva Jäger Thamer Sliwa Ralph Simanek Heinz Gisslinger Ulrich Jäger Klaus Geissler

Leuk Res 2014 Jan 14;38(1):116-20. Epub 2013 Oct 14.

5th Department of Internal Medicine - Oncology/Hematology, Hospital Hietzing, Vienna, Austria; Ludwig Boltzmann Institute for Clinical Oncology, Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2013.10.003DOI Listing
January 2014

Three-year efficacy, safety, and survival findings from COMFORT-II, a phase 3 study comparing ruxolitinib with best available therapy for myelofibrosis.

Authors:
Francisco Cervantes Alessandro M Vannucchi Jean-Jacques Kiladjian Haifa Kathrin Al-Ali Andres Sirulnik Viktoriya Stalbovskaya Mari McQuitty Deborah S Hunter Richard S Levy Francesco Passamonti Tiziano Barbui Giovanni Barosi Claire N Harrison Laurent Knoops Heinz Gisslinger

Blood 2013 Dec 30;122(25):4047-53. Epub 2013 Oct 30.

Hospital Clínic, Hematology Department, Institut d'Investigació Biomédica August Pi i Sunyer, University of Barcelona, Barcelona, Spain;

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http://dx.doi.org/10.1182/blood-2013-02-485888DOI Listing
December 2013

Somatic mutations of calreticulin in myeloproliferative neoplasms.

Authors:
Thorsten Klampfl Heinz Gisslinger Ashot S Harutyunyan Harini Nivarthi Elisa Rumi Jelena D Milosevic Nicole C C Them Tiina Berg Bettina Gisslinger Daniela Pietra Doris Chen Gregory I Vladimer Klaudia Bagienski Chiara Milanesi Ilaria Carola Casetti Emanuela Sant'Antonio Virginia Ferretti Chiara Elena Fiorella Schischlik Ciara Cleary Melanie Six Martin Schalling Andreas Schönegger Christoph Bock Luca Malcovati Cristiana Pascutto Giulio Superti-Furga Mario Cazzola Robert Kralovics

N Engl J Med 2013 Dec 10;369(25):2379-90. Epub 2013 Dec 10.

From CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences (T.K., A.S.H., H.N., J.D.M., N.C.C.T., T.B., D.C., G.I.V., K.B., F.S., C.C., M. Six, A.S., C.B., G.S.-F., R.K.) and the Department of Internal Medicine I, Division of Hematology and Blood Coagulation, Medical University of Vienna (H.G., B.G., M. Schalling, R.K.) - both in Vienna; and the Department of Hematology Oncology, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo (E.R., D.P., C.M., I.C.C., E.S., V.F., C.E., L.M., C.P., M.C.), and the Department of Molecular Medicine, University of Pavia (L.M., M.C.) - both in Pavia, Italy.

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http://dx.doi.org/10.1056/NEJMoa1311347DOI Listing
December 2013

Revised response criteria for myelofibrosis: International Working Group-Myeloproliferative Neoplasms Research and Treatment (IWG-MRT) and European LeukemiaNet (ELN) consensus report.

Authors:
Ayalew Tefferi Francisco Cervantes Ruben Mesa Francesco Passamonti Srdan Verstovsek Alessandro M Vannucchi Jason Gotlib Brigitte Dupriez Animesh Pardanani Claire Harrison Ronald Hoffman Heinz Gisslinger Nicolaus Kröger Juergen Thiele Tiziano Barbui Giovanni Barosi

Blood 2013 Aug 9;122(8):1395-8. Epub 2013 Jul 9.

Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1182/blood-2013-03-488098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4828070PMC
August 2013

Health-related quality of life and symptoms in patients with myelofibrosis treated with ruxolitinib versus best available therapy.

Authors:
Claire N Harrison Ruben A Mesa Jean-Jacques Kiladjian Haifa-Kathrin Al-Ali Heinz Gisslinger Laurent Knoops Margaret Squier Andres Sirulnik Estella Mendelson Xiaolei Zhou Catherine Copley-Merriman Deborah S Hunter Richard S Levy Francisco Cervantes Francesco Passamonti Tiziano Barbui Giovanni Barosi Alessandro M Vannucchi

Br J Haematol 2013 Jul 14;162(2):229-39. Epub 2013 May 14.

Guy's and St. Thomas' NHS Foundation Trust, Guy's Hospital, London, UK.

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http://dx.doi.org/10.1111/bjh.12375DOI Listing
July 2013

High expression of cereblon (CRBN) is associated with improved clinical response in patients with multiple myeloma treated with lenalidomide and dexamethasone.

Authors:
Daniel Heintel Alberto Rocci Heinz Ludwig Arnold Bolomsky Simona Caltagirone Martin Schreder Sabine Pfeifer Heinz Gisslinger Niklas Zojer Ulrich Jäger Antonio Palumbo

Br J Haematol 2013 Jun 9;161(5):695-700. Epub 2013 Apr 9.

Department of Internal Medicine I, Center for Oncology and Haematology, Wilhelminenspital, Vienna, Austria.

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http://dx.doi.org/10.1111/bjh.12338DOI Listing
June 2013

Revised response criteria for polycythemia vera and essential thrombocythemia: an ELN and IWG-MRT consensus project.

Authors:
Giovanni Barosi Ruben Mesa Guido Finazzi Claire Harrison Jean-Jacques Kiladjian Eva Lengfelder Mary F McMullin Francesco Passamonti Alessandro M Vannucchi Carlos Besses Heinz Gisslinger Jan Samuelsson Srdan Verstovsek Ronald Hoffman Animesh Pardanani Francisco Cervantes Ayalew Tefferi Tiziano Barbui

Blood 2013 Jun 16;121(23):4778-81. Epub 2013 Apr 16.

Center for the Study of Myelofibrosis, Biotechnology Research Area, Istituto di Ricovero e Cura a Carattere Scientifico Policlinico S. Matteo Foundation, Pavia, Italy.

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http://dx.doi.org/10.1182/blood-2013-01-478891DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674675PMC
June 2013

Experience with lenalidomide in an Austrian non-study population with advanced myelofibrosis.

Authors:
Sonja Burgstaller Michael Fridrik Sabine Hojas Thomas Kühr Heinz Ludwig Beate Mayrbäurl Rainer Pöhnl Michael Pötscher Ernst Schlögl Daniela Zauner Josef Thaler Heinz Gisslinger

Wien Klin Wochenschr 2013 Apr 28;125(7-8):196-9. Epub 2013 Mar 28.

Innere Medizin IV, Klinikum Wels-Grieskirchen, Grieskirchnerstraße 42, 4600 Wels, Austria.

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http://dx.doi.org/10.1007/s00508-013-0345-zDOI Listing
April 2013

Anagrelide compared with hydroxyurea in WHO-classified essential thrombocythemia: the ANAHYDRET Study, a randomized controlled trial.

Authors:
Heinz Gisslinger Mirjana Gotic Jerzy Holowiecki Miroslav Penka Juergen Thiele Hans-Michael Kvasnicka Robert Kralovics Petro E Petrides

Blood 2013 Mar 11;121(10):1720-8. Epub 2013 Jan 11.

Medical University of Vienna, Department of Internal Medicine I, Division of Hematology and Blood Coagulation, Vienna, Austria.

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http://dx.doi.org/10.1182/blood-2012-07-443770DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591796PMC
March 2013

Development and validation of an International Prognostic Score of thrombosis in World Health Organization-essential thrombocythemia (IPSET-thrombosis).

Authors:
Tiziano Barbui Guido Finazzi Alessandra Carobbio Juergen Thiele Francesco Passamonti Elisa Rumi Marco Ruggeri Francesco Rodeghiero Maria Luigia Randi Irene Bertozzi Heinz Gisslinger Veronika Buxhofer-Ausch Valerio De Stefano Silvia Betti Alessandro Rambaldi Alessandro M Vannucchi Ayalew Tefferi

Blood 2012 Dec 1;120(26):5128-33; quiz 5252. Epub 2012 Oct 1.

Ospedali Riuniti di Bergamo, Bergamo, Italy.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2012-07-44
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http://dx.doi.org/10.1182/blood-2012-07-444067DOI Listing
December 2012

Clinical significance of genetic aberrations in secondary acute myeloid leukemia.

Authors:
Jelena D Milosevic Ana Puda Luca Malcovati Tiina Berg Michael Hofbauer Alexey Stukalov Thorsten Klampfl Ashot S Harutyunyan Heinz Gisslinger Bettina Gisslinger Tatiana Burjanivova Elisa Rumi Daniela Pietra Chiara Elena Alessandro M Vannucchi Michael Doubek Dana Dvorakova Blanka Robesova Rotraud Wieser Elisabeth Koller Nada Suvajdzic Dragica Tomin Natasa Tosic Jacques Colinge Zdenek Racil Michael Steurer Sonja Pavlovic Mario Cazzola Robert Kralovics

Am J Hematol 2012 Nov 7;87(11):1010-6. Epub 2012 Aug 7.

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.

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http://dx.doi.org/10.1002/ajh.23309DOI Listing
November 2012

Overexpression of G protein-coupled receptor 5D in the bone marrow is associated with poor prognosis in patients with multiple myeloma.

Authors:
Johanna Atamaniuk Andreas Gleiss Edit Porpaczy Birgit Kainz Thomas W Grunt Markus Raderer Bernadette Hilgarth Johannes Drach Heinz Ludwig Heinz Gisslinger Ulrich Jaeger Alexander Gaiger

Eur J Clin Invest 2012 Sep 16;42(9):953-60. Epub 2012 May 16.

Department of Medicine I, Division of Hematology and Hemostaseology, Medical University Vienna, Austria.

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http://dx.doi.org/10.1111/j.1365-2362.2012.02679.xDOI Listing
September 2012

A prognostic model to predict survival in 867 World Health Organization-defined essential thrombocythemia at diagnosis: a study by the International Working Group on Myelofibrosis Research and Treatment.

Authors:
Francesco Passamonti Jürgen Thiele Francois Girodon Elisa Rumi Alessandra Carobbio Heinz Gisslinger Hans Michael Kvasnicka Marco Ruggeri Maria Luigia Randi Naseema Gangat Alessandro Maria Vannucchi Andrea Gianatti Bettina Gisslinger Leonhard Müllauer Francesco Rodeghiero Emanuele S G d'Amore Irene Bertozzi Curtis A Hanson Emanuela Boveri Filippo Marino Margherita Maffioli Domenica Caramazza Elisabetta Antonioli Valentina Carrai Veronika Buxhofer-Ausch Cristiana Pascutto Mario Cazzola Tiziano Barbui Ayalew Tefferi

Blood 2012 Aug 26;120(6):1197-201. Epub 2012 Jun 26.

Division of Hematology, Department of Internal Medicine, University Hospital Ospedale di Circolo e Fondazione Macchi, Varese, Italy.

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August 2012

Leukocytosis as an important risk factor for arterial thrombosis in WHO-defined early/prefibrotic myelofibrosis: an international study of 264 patients.

Authors:
Veronika Buxhofer-Ausch Heinz Gisslinger Jürgen Thiele Bettina Gisslinger Hans-Michael Kvasnicka Leonhard Müllauer Sophie Frantal Alessandra Carobbio Francesco Passamonti Elisa Rumi Marco Ruggeri Francesco Rodeghiero Maria L Randi Irene Bertozzi Alessandro M Vannucchi Elisabetta Antonioli Guido Finazzi Naseema Gangat Ayalew Tefferi Tiziano Barbui

Am J Hematol 2012 Jul 10;87(7):669-72. Epub 2012 May 10.

Division of Hematology and Blood Coagulation, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1002/ajh.23217DOI Listing
July 2012

Disease characteristics and clinical outcome in young adults with essential thrombocythemia versus early/prefibrotic primary myelofibrosis.

Authors:
Tiziano Barbui Jürgen Thiele Alessandra Carobbio Francesco Passamonti Elisa Rumi Maria Luigia Randi Irene Bertozzi Alessandro M Vannucchi Heinz Gisslinger Bettina Gisslinger Guido Finazzi Marco Ruggeri Francesco Rodeghiero Alessandro Rambaldi Naseema Gangat Ayalew Tefferi

Blood 2012 Jul 13;120(3):569-71. Epub 2012 Jun 13.

Ospedali Riuniti di Bergamo, Largo Barozzi 1, Bergamo, Italy.

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http://dx.doi.org/10.1182/blood-2012-01-407981DOI Listing
July 2012

Successful treatment sequence incorporating bevacizumab for therapy of polyneuropathy in two patients with POEMS syndrome.

Authors:
Veronika Buxhofer-Ausch Bettina Gisslinger Gerhard Stangl Helmut Rauschka Heinz Gisslinger

Leuk Res 2012 May 25;36(5):e98-e100. Epub 2012 Feb 25.

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http://dx.doi.org/10.1016/j.leukres.2012.01.018DOI Listing
May 2012

Unraveling the genetic underpinnings of myeloproliferative neoplasms and understanding their effect on disease course and response to therapy: proceedings from the 6th International Post-ASH Symposium.

Authors:
Omar Abdel-Wahab Animesh Pardanani Olivier A Bernard Guido Finazzi John D Crispino Heinz Gisslinger Robert Kralovics Olatoyosi Odenike Kapil Bhalla Vikas Gupta Giovanni Barosi Jason Gotlib Paola Guglielmelli Jean-Jacques Kiladjian Pierre Noel Mario Cazzola Alessandro M Vannucchi Ronald Hoffman Tiziano Barbui Juergen Thiele Richard A Van Etten Tariq Mughal Ayalew Tefferi

Am J Hematol 2012 May 28;87(5):562-8. Epub 2012 Mar 28.

Leukemia Service and Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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http://dx.doi.org/10.1002/ajh.23169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491640PMC
May 2012

Continuous lenalidomide treatment for newly diagnosed multiple myeloma.

Authors:
Antonio Palumbo Roman Hajek Michel Delforge Martin Kropff Maria Teresa Petrucci John Catalano Heinz Gisslinger Wiesław Wiktor-Jędrzejczak Mamia Zodelava Katja Weisel Nicola Cascavilla Genadi Iosava Michele Cavo Janusz Kloczko Joan Bladé Meral Beksac Ivan Spicka Torben Plesner Joergen Radke Christian Langer Dina Ben Yehuda Alessandro Corso Lindsay Herbein Zhinuan Yu Jay Mei Christian Jacques Meletios A Dimopoulos

N Engl J Med 2012 May;366(19):1759-69

Myeloma Unit, Division of Hematology, University of Turin, Azienda Ospedaliero-Universitaria, S. Giovanni Battista, Via Genova 3, 10126 Turin, Italy.

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http://dx.doi.org/10.1056/NEJMoa1112704DOI Listing
May 2012

Frequent deletions of JARID2 in leukemic transformation of chronic myeloid malignancies.

Authors:
Ana Puda Jelena D Milosevic Tiina Berg Thorsten Klampfl Ashot S Harutyunyan Bettina Gisslinger Elisa Rumi Daniela Pietra Luca Malcovati Chiara Elena Michael Doubek Michael Steurer Natasa Tosic Sonja Pavlovic Paola Guglielmelli Lisa Pieri Alessandro M Vannucchi Heinz Gisslinger Mario Cazzola Robert Kralovics

Am J Hematol 2012 Mar 21;87(3):245-50. Epub 2011 Dec 21.

Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.

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http://dx.doi.org/10.1002/ajh.22257DOI Listing
March 2012

Initial bone marrow reticulin fibrosis in polycythemia vera exerts an impact on clinical outcome.

Authors:
Tiziano Barbui Jürgen Thiele Francesco Passamonti Elisa Rumi Emanuela Boveri Maria Luigia Randi Irene Bertozzi Filippo Marino Alessandro M Vannucchi Lisa Pieri Giada Rotunno Heinz Gisslinger Bettina Gisslinger Leonhard Müllauer Guido Finazzi Alessandra Carobbio Andrea Gianatti Marco Ruggeri Ilaria Nichele Emanuele D'Amore Alessandro Rambaldi Ayalew Tefferi

Blood 2012 Mar 13;119(10):2239-41. Epub 2012 Jan 13.

Ospedali Riuniti di Bergamo, Italy.

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http://dx.doi.org/10.1182/blood-2011-11-393819DOI Listing
March 2012

JAK inhibition with ruxolitinib versus best available therapy for myelofibrosis.

Authors:
Claire Harrison Jean-Jacques Kiladjian Haifa Kathrin Al-Ali Heinz Gisslinger Roger Waltzman Viktoriya Stalbovskaya Mari McQuitty Deborah S Hunter Richard Levy Laurent Knoops Francisco Cervantes Alessandro M Vannucchi Tiziano Barbui Giovanni Barosi

N Engl J Med 2012 Mar;366(9):787-98

Guy's and St. Thomas' National Health Service Foundation Trust, Guy's Hospital, London, United Kingdom.

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http://dx.doi.org/10.1056/NEJMoa1110556DOI Listing
March 2012

European Bone Marrow Working Group trial on reproducibility of World Health Organization criteria to discriminate essential thrombocythemia from prefibrotic primary myelofibrosis. Haematologica 2012;97(3):360-5--comment.

Authors:
Jürgen Thiele Attilio Orazi Hans Michael Kvasnicka Vito Franco Emanuela Boveri Umberto Gianelli Heinz Gisslinger Francesco Passamonti Ayalew Tefferi Tiziano Barbui

Haematologica 2012 Mar;97(3):e5-6; discussion e7-8

Institute for Pathology, University of Cologne, Kerpener Str. 62, D-50924 Cologne, Germany.

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http://dx.doi.org/10.3324/haematol.2011.061432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291579PMC
March 2012

Identification of oncostatin M as a JAK2 V617F-dependent amplifier of cytokine production and bone marrow remodeling in myeloproliferative neoplasms.

Authors:
Gregor Hoermann Sabine Cerny-Reiterer Harald Herrmann Katharina Blatt Martin Bilban Heinz Gisslinger Bettina Gisslinger Leonhard Müllauer Robert Kralovics Christine Mannhalter Peter Valent Matthias Mayerhofer

FASEB J 2012 Feb 3;26(2):894-906. Epub 2011 Nov 3.

Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1096/fj.11-193078DOI Listing
February 2012

Blood tests may predict early primary myelofibrosis in patients presenting with essential thrombocythemia.

Authors:
Alessandra Carobbio Guido Finazzi Juergen Thiele Hans-Michael Kvasnicka Francesco Passamonti Elisa Rumi Marco Ruggeri Francesco Rodeghiero Maria Luigia Randi Irene Bertozzi Alessandro M Vannucchi Elisabetta Antonioli Heinz Gisslinger Veronika Buxhofer-Ausch Naseema Gangat Alessandro Rambaldi Ayalew Tefferi Tiziano Barbui

Am J Hematol 2012 Feb 11;87(2):203-4. Epub 2012 Jan 11.

Division of Hematology, Ospedali Riuniti di Bergamo, Bergamo, Italy.

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http://dx.doi.org/10.1002/ajh.22241DOI Listing
February 2012

Asymmetric dimethylarginine levels in essential thrombocythemia--a retrospective analysis.

Authors:
Daniele Massera Friedrich Mittermayer Bettina Gisslinger Damla Olcaydu Michael Wolzt Heinz Gisslinger

Ann Hematol 2011 Sep 3;90(9):1105-6. Epub 2010 Dec 3.

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http://link.springer.com/10.1007/s00277-010-1127-6
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http://dx.doi.org/10.1007/s00277-010-1127-6DOI Listing
September 2011

Lenalidomide downregulates the cell survival factor, interferon regulatory factor-4, providing a potential mechanistic link for predicting response.

Authors:
Antonia Lopez-Girona Daniel Heintel Ling-Hua Zhang Derek Mendy Svetlana Gaidarova Helen Brady Justin Blake Bartlett Peter H Schafer Martin Schreder Arnold Bolomsky Bernadette Hilgarth Niklas Zojer Heinz Gisslinger Heinz Ludwig Tom Daniel Ulrich Jäger Rajesh Chopra

Br J Haematol 2011 Aug 24;154(3):325-36. Epub 2011 Jun 24.

Translational Development Department, Celgene, San Diego, CA 92122, USA.

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http://dx.doi.org/10.1111/j.1365-2141.2011.08689.xDOI Listing
August 2011

Survival and disease progression in essential thrombocythemia are significantly influenced by accurate morphologic diagnosis: an international study.

Authors:
Tiziano Barbui Juergen Thiele Francesco Passamonti Elisa Rumi Emanuela Boveri Marco Ruggeri Francesco Rodeghiero Emanuele S G d'Amore Maria Luigia Randi Irene Bertozzi Filippo Marino Alessandro M Vannucchi Elisabetta Antonioli Valentina Carrai Heinz Gisslinger Veronika Buxhofer-Ausch Leonhard Müllauer Alessandra Carobbio Andrea Gianatti Naseema Gangat Curtis A Hanson Ayalew Tefferi

J Clin Oncol 2011 Aug 11;29(23):3179-84. Epub 2011 Jul 11.

Ospedali Riuniti di Bergamo, Bergamo, Italy.

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http://jco.ascopubs.org/content/early/2011/07/06/JCO.2010.34
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2010.34.5298
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http://dx.doi.org/10.1200/JCO.2010.34.5298DOI Listing
August 2011

Genome integrity of myeloproliferative neoplasms in chronic phase and during disease progression.

Authors:
Thorsten Klampfl Ashot Harutyunyan Tiina Berg Bettina Gisslinger Martin Schalling Klaudia Bagienski Damla Olcaydu Francesco Passamonti Elisa Rumi Daniela Pietra Roland Jäger Lisa Pieri Paola Guglielmelli Ilaria Iacobucci Giovanni Martinelli Mario Cazzola Alessandro M Vannucchi Heinz Gisslinger Robert Kralovics

Blood 2011 Jul 29;118(1):167-76. Epub 2011 Apr 29.

Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.

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http://dx.doi.org/10.1182/blood-2011-01-331678DOI Listing
July 2011

Risk factors for arterial and venous thrombosis in WHO-defined essential thrombocythemia: an international study of 891 patients.

Authors:
Alessandra Carobbio Juergen Thiele Francesco Passamonti Elisa Rumi Marco Ruggeri Francesco Rodeghiero Maria Luigia Randi Irene Bertozzi Alessandro M Vannucchi Elisabetta Antonioli Heinz Gisslinger Veronika Buxhofer-Ausch Guido Finazzi Naseema Gangat Ayalew Tefferi Tiziano Barbui

Blood 2011 Jun 13;117(22):5857-9. Epub 2011 Apr 13.

Ospedali Riuniti di Bergamo, Largo Barozzi 1, Bergamo, Italy.

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http://dx.doi.org/10.1182/blood-2011-02-339002DOI Listing
June 2011

Essential thrombocythemia versus early primary myelofibrosis: a multicenter study to validate the WHO classification.

Authors:
Jürgen Thiele Hans Michael Kvasnicka Leonhard Müllauer Veronika Buxhofer-Ausch Bettina Gisslinger Heinz Gisslinger

Blood 2011 May 29;117(21):5710-8. Epub 2011 Mar 29.

Institute of Pathology, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1182/blood-2010-07-293761DOI Listing
May 2011

FLT3-mediated p38-MAPK activation participates in the control of megakaryopoiesis in primary myelofibrosis.

Authors:
Christophe Desterke Chrystele Bilhou-Nabéra Bernadette Guerton Christophe Martinaud Carole Tonetti Denis Clay Paola Guglielmelli Alessandro Vannucchi Dominique Bordessoule Hans Hasselbalch Brigitte Dupriez Nassima Benzoubir Marie-Françoise Bourgeade Olivier Pierre-Louis Vladimir Lazar William Vainchenker Annelise Bennaceur-Griscelli Heinz Gisslinger Stéphane Giraudier Marie-Caroline Le Bousse-Kerdilès

Cancer Res 2011 Apr 12;71(8):2901-15. Epub 2011 Apr 12.

INSERM U972, Paris-11 University, Institut André Lwoff, Villejuif, France.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-1731DOI Listing
April 2011

Molecular and clinical features of the myeloproliferative neoplasm associated with JAK2 exon 12 mutations.

Authors:
Francesco Passamonti Chiara Elena Susanne Schnittger Radek C Skoda Anthony R Green François Girodon Jean-Jacques Kiladjian Mary Frances McMullin Marco Ruggeri Carles Besses Alessandro M Vannucchi Eric Lippert Heinz Gisslinger Elisa Rumi Thomas Lehmann Christina A Ortmann Daniela Pietra Cristiana Pascutto Torsten Haferlach Mario Cazzola

Blood 2011 Mar 11;117(10):2813-6. Epub 2011 Jan 11.

Department of Hematology Oncology, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.

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http://dx.doi.org/10.1182/blood-2010-11-316810DOI Listing
March 2011

Light chain-induced acute renal failure can be reversed by bortezomib-doxorubicin-dexamethasone in multiple myeloma: results of a phase II study.

Authors:
Heinz Ludwig Zdenek Adam Roman Hajek Richard Greil Elena Tóthová Felix Keil Eva Maria Autzinger Josef Thaler Heinz Gisslinger Alois Lang Miklós Egyed Irene Womastek Niklas Zojer

J Clin Oncol 2010 Oct 7;28(30):4635-41. Epub 2010 Sep 7.

Department of Medicine I, Center of Oncology and Hematology, Wilhelminenspital, Vienna, Austria.

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http://dx.doi.org/10.1200/JCO.2010.28.1238DOI Listing
October 2010

Thalidomide maintenance treatment increases progression-free but not overall survival in elderly patients with myeloma.

Authors:
Heinz Ludwig Zdenek Adam Elena Tóthová Roman Hajek Boris Labar Miklós Egyed Ivan Spicka Heinz Gisslinger Johannes Drach Ingrid Kuhn Axel Hinke Niklas Zojer

Haematologica 2010 Sep 23;95(9):1548-54. Epub 2010 Apr 23.

Department of Medicine I, Center for Oncology and Hematology, Wilhelminenspital, Vienna, Austria.

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http://dx.doi.org/10.3324/haematol.2009.020586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930957PMC
September 2010

Imatinib, cytokines and interstitial lung disease in a patient with primary myelofibrosis.

Authors:
Bruno Robibaro Anna Kropfmueller Mathias Prokop Paul Haber Heinz Gisslinger

Ann Hematol 2010 Aug 19;89(8):829-31. Epub 2009 Dec 19.

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http://dx.doi.org/10.1007/s00277-009-0884-6DOI Listing
August 2010

Bone marrow fibrosis and diagnosis of essential thrombocythemia.

Authors:
Juergen Thiele Hans Michael Kvasnicka James W Vardiman Attilio Orazi Vito Franco Heinz Gisslinger Gunnar Birgegard Martin Griesshammer Ayalew Tefferi

J Clin Oncol 2009 Dec 26;27(34):e220-1; author reply e222-3. Epub 2009 Oct 26.

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http://dx.doi.org/10.1200/JCO.2009.24.3485DOI Listing
December 2009

Pomalidomide is active in the treatment of anemia associated with myelofibrosis.

Authors:
Ayalew Tefferi Srdan Verstovsek Giovanni Barosi Francesco Passamonti Gail J Roboz Heinz Gisslinger Ronald L Paquette Francisco Cervantes Candido E Rivera H Joachim Deeg Juergen Thiele Hans M Kvasnicka James W Vardiman Yanming Zhang B Nebiyou Bekele Ruben A Mesa Robert P Gale Hagop M Kantarjian

J Clin Oncol 2009 Sep 3;27(27):4563-9. Epub 2009 Aug 3.

Mayo Clinic, 200 First St SW, Rochester MN 55905, USA.

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http://dx.doi.org/10.1200/JCO.2008.21.7356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979191PMC
September 2009

Thalidomide-dexamethasone compared with melphalan-prednisolone in elderly patients with multiple myeloma.

Authors:
Heinz Ludwig Roman Hajek Elena Tóthová Johannes Drach Zdenek Adam Boris Labar Miklós Egyed Ivan Spicka Heinz Gisslinger Richard Greil Ingrid Kuhn Niklas Zojer Axel Hinke

Blood 2009 Apr 27;113(15):3435-42. Epub 2008 Oct 27.

Department of Medicine I, Wilhelminenspital Vienna, Vienna, Austria.

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http://dx.doi.org/10.1182/blood-2008-07-169565DOI Listing
April 2009

A common JAK2 haplotype confers susceptibility to myeloproliferative neoplasms.

Authors:
Damla Olcaydu Ashot Harutyunyan Roland Jäger Tiina Berg Bettina Gisslinger Ingrid Pabinger Heinz Gisslinger Robert Kralovics

Nat Genet 2009 Apr 15;41(4):450-4. Epub 2009 Mar 15.

Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.

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http://dx.doi.org/10.1038/ng.341DOI Listing
April 2009

Acquired resistance to interferon alpha therapy associated with homozygous MPL-W515L mutation and chromosome 20q deletion in primary myelofibrosis.

Authors:
Veronika Buxhofer-Ausch Heinz Gisslinger Tiina Berg Bettina Gisslinger Robert Kralovics

Eur J Haematol 2009 Feb 10;82(2):161-3. Epub 2008 Nov 10.

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http://dx.doi.org/10.1111/j.1600-0609.2008.01183.xDOI Listing
February 2009

Clonal analysis of deletions on chromosome 20q and JAK2-V617F in MPD suggests that del20q acts independently and is not one of the predisposing mutations for JAK2-V617F.

Authors:
Franz X Schaub Roland Jäger Renate Looser Hui Hao-Shen Sylvie Hermouet François Girodon Andre Tichelli Heinz Gisslinger Robert Kralovics Radek C Skoda

Blood 2009 Feb 1;113(9):2022-7. Epub 2008 Dec 1.

Department of Biomedicine, Experimental Hematology, University Hospital Basel, Basel, Switzerland.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2008-07-16
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http://dx.doi.org/10.1182/blood-2008-07-167056DOI Listing
February 2009

Pharmacokinetics, bioequivalence, tolerability, and effects on platelet counts of two formulations of anagrelide in healthy volunteers and patients with thrombocythemia associated with chronic myeloproliferation.

Authors:
Petro E Petrides Heinz Gisslinger Michael Steurer Werner Linkesch Günther Krumpl Agnes Schüller Rudolf Widmann

Clin Ther 2009 Feb;31(2):386-98

Hematology Oncology Center Munich and Ludwig Maximilians University of Munich Medical School, Munich, Germany.

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http://dx.doi.org/10.1016/j.clinthera.2009.02.008DOI Listing
February 2009