Heinz Decker

Heinz Decker

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Heinz Decker

Heinz Decker

Publications by authors named "Heinz Decker"

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71Publications

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The Recent Crystal Structure of Human Tyrosinase Related Protein 1 (HsTYRP1) Solves an Old Problem and Poses a New One.

Angew Chem Int Ed Engl 2017 Nov 9;56(46):14352-14354. Epub 2017 Oct 9.

Institute of Inorganic Chemistry, Christian Alberts University Kiel, Max Eyth Strasse 2, 24118, Kiel, Germany.

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November 2017

Proteomic profiling of German Dornfelder grape berries using data-independent acquisition.

Plant Physiol Biochem 2017 Sep 7;118:64-70. Epub 2017 Jun 7.

Institute for Molecular Physiology, Molecular Biophysics, Johannes Gutenberg University Mainz, Jakob-Welder-Weg, 26, D-55128 Mainz, Germany. Electronic address:

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September 2017

Antioxidant capacity of phenolic compounds on human cell lines as affected by grape-tyrosinase and Botrytis-laccase oxidation.

Food Chem 2017 Aug 2;229:779-789. Epub 2017 Mar 2.

Institute for Molecular Biophysics, Johannes Gutenberg-University Mainz, Jakob-Welder Weg 26, 55128 Mainz, Germany. Electronic address:

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August 2017

Immunological properties of oxygen-transport proteins: hemoglobin, hemocyanin and hemerythrin.

Cell Mol Life Sci 2017 01 12;74(2):293-317. Epub 2016 Aug 12.

Institut für Molekulare Biophysik, Johannes Gutenberg-Universität Mainz, Jakob Welder-Weg 28, 55128, Mainz, Germany.

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January 2017

Past, present and future of immunology in Mainz.

Cell Immunol 2016 10;308:1-6

Research Center for Immunotherapy (FZI), University Medical Center of the Johannes Gutenberg University, Mainz, Germany; Institute for Immunology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.

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October 2016

Influence of polysaccharides on wine protein aggregation.

Food Chem 2016 Jun 24;200:38-45. Epub 2015 Dec 24.

Institute for Molecular Biophysics, Johannes Gutenberg-University Mainz, Jakob Welder Weg 26, 55128 Mainz, Germany. Electronic address:

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June 2016

Tyrosinase versus Catechol Oxidase: One Asparagine Makes the Difference.

Angew Chem Int Ed Engl 2016 Feb 15;55(8):2884-8. Epub 2016 Jan 15.

Institute of Molecular Biophysics, Johannes Gutenberg University, Jakob Welder Weg 26, 55128, Mainz, Germany.

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February 2016

Large oligomeric complex structures can be computationally assembled by efficiently combining docked interfaces.

Proteins 2015 Oct 24;83(10):1887-99. Epub 2015 Aug 24.

Institute of Computer Science, Johannes Gutenberg University, Staudingerweg 9, Mainz, 55128, Germany.

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October 2015

Polyphenoloxidase from Riesling and Dornfelder wine grapes (Vitis vinifera) is a tyrosinase.

Food Chem 2015 Sep 14;183:49-57. Epub 2015 Mar 14.

Institute for Molecular Biophysics, Johannes Gutenberg-University Mainz, Jakob-Welder-Weg 26, 55128 Mainz, Germany.

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September 2015

Influence of Laccase and Tyrosinase on the Antioxidant Capacity of Selected Phenolic Compounds on Human Cell Lines.

Molecules 2015 Sep 18;20(9):17194-207. Epub 2015 Sep 18.

Institute for Molecular Biophysics, Johannes Gutenberg University of Mainz, Jakob-Welder-Weg, 26, 55128 Mainz, Germany.

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September 2015

Lipoprotein-induced phenoloxidase-activity in tarantula hemocyanin.

Biochim Biophys Acta 2015 Aug 24;1854(8):939-49. Epub 2015 Mar 24.

Institut für Molekulare Biophysik, Johannes Gutenberg-Universität Mainz, Jakob Welder-Weg 28, 55128 Mainz, Germany.

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August 2015

Fasted-state simulated intestinal fluid "FaSSIF-C", a cholesterol containing intestinal model medium for in vitro drug delivery development.

J Pharm Sci 2015 Jul 11;104(7):2213-24. Epub 2015 May 11.

Forschungszentrum Jülich GmbH, Jülich Centre for Neutron Science (JCNS) at Heinz Maier-Leibnitz Zentrum (MLZ), Garching, D-85747, Germany.

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July 2015

Assessment of sensitization to grape and wine allergens as possible causes of adverse reactions to wine: a pilot study.

Clin Transl Allergy 2015 22;5:21. Epub 2015 Jun 22.

Institute for Molecular Biophysics, Johannes Gutenberg-University Mainz, Jakob-Welder-Weg 26, D-55128 Mainz, Germany.

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June 2015

Wild-type Cu/Zn superoxide dismutase stabilizes mutant variants by heterodimerization.

Neurobiol Dis 2014 Feb 4;62:479-88. Epub 2013 Nov 4.

Institute for Pathobiochemistry, University Medical Center, Johannes Gutenberg-University Mainz, Duesbergweg 6, 55128 Mainz, Germany. Electronic address:

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February 2014

Engineering of a bacterial tyrosinase for improved catalytic efficiency towards D-tyrosine using random and site directed mutagenesis approaches.

Biotechnol Bioeng 2013 Jul 22;110(7):1849-57. Epub 2013 Feb 22.

School of Biomolecular and Biomedical Sciences, Ardmore House, University College Dublin, Belfield, Dublin 4, Ireland.

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July 2013

Purification and structural characterisation of lipid transfer protein from red wine and grapes.

Food Chem 2013 May 8;138(1):263-9. Epub 2012 Nov 8.

Institute for Molecular Biophysics, Johannes Gutenberg-University Mainz, Jakob Welder-Weg 26, 55128 Mainz, Germany.

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May 2013

In reply.

Dtsch Arztebl Int 2013 Jan 18;110(3):40. Epub 2013 Jan 18.

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January 2013

Crystallization and preliminary analysis of crystals of the 24-meric hemocyanin of the emperor scorpion (Pandinus imperator).

PLoS One 2012 5;7(3):e32548. Epub 2012 Mar 5.

Institut für Molekulare Biophysik, Johannes Gutenberg-Universität, Mainz, Germany.

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July 2012

Prevalence of wine intolerance: results of a survey from Mainz, Germany.

Dtsch Arztebl Int 2012 Jun 22;109(25):437-44. Epub 2012 Jun 22.

Institute of Molecular Biophysics of the Johannes Gutenberg University Mainz.

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June 2012

Copper-O2 reactivity of tyrosinase models towards external monophenolic substrates: molecular mechanism and comparison with the enzyme.

Chem Soc Rev 2011 Jul 17;40(7):4077-98. Epub 2011 Mar 17.

Institut für Anorganische Chemie, Christian-Albrechts-Universität zu Kiel, Max-Eyth-Straße 2, 24118 Kiel, Germany.

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July 2011

The refined structure of functional unit h of keyhole limpet hemocyanin (KLH1-h) reveals disulfide bridges.

IUBMB Life 2011 Mar;63(3):183-7

Institut für Molekulare Biophysik, Johannes Gutenberg-Universität, Jakob Welder Weg 26, Mainz, Germany.

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March 2011

Cockroach allergens Per a 3 are oligomers.

Dev Comp Immunol 2010 Jul 31;34(7):722-33. Epub 2010 Jan 31.

Institute for Molecular Biophysics, University of Mainz, Jakob Welder Weg 26, Mainz, Germany.

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July 2010

Monte Carlo-based rigid body modelling of large protein complexes against small angle scattering data.

Comput Biol Chem 2010 Jun 2;34(3):158-64. Epub 2010 Jun 2.

Institute for Molecular Biophysics, Jakob-Welder-Weg 26, 55126 Mainz, Germany.

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June 2010

Cupredoxin-like domains in haemocyanins.

Biochem J 2010 Feb 24;426(3):373-8. Epub 2010 Feb 24.

Institut für Molekulare Biophysik, Johannes Gutenberg-Universität, Jakob Welder Weg 26, 55128 Mainz, Germany.

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February 2010

Is activated hemocyanin instead of phenoloxidase involved in immune response in woodlice?

Dev Comp Immunol 2009 Oct 28;33(10):1055-63. Epub 2009 May 28.

Institut für Molekulare Biophysik, Johannes Gutenberg Universität, 55099 Mainz, Germany.

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October 2009

Analysis of protein composition of red wine in comparison with rosé and white wines by electrophoresis and high-pressure liquid chromatography-mass spectrometry (HPLC-MS).

J Agric Food Chem 2009 May 22;57(10):4328-33. Epub 2009 Apr 22.

Institute of Molecular Biophysics of the Johannes Gutenberg University Mainz, Germany.

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May 2009

Structural characterization of the alpha-hemolysin monomer from Staphylococcus aureus.

Proteins 2009 Apr;75(1):118-26

Institute of Molecular Biophysics, University of Mainz, Mainz, Germany.

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April 2009

Tryptophan quenching as linear sensor for oxygen binding of arthropod hemocyanins.

Biochim Biophys Acta 2008 Oct 7;1780(10):1143-7. Epub 2008 Jul 7.

Institute of Physical Chemistry, Jakob Welderweg 11, 55099 Mainz, Germany.

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October 2008

Kinetic properties of hexameric tyrosinase from the crustacean Palinurus elephas.

Photochem Photobiol 2008 May-Jun;84(3):692-9. Epub 2008 Apr 12.

Institut für Molekulare Biophysik, Johannes-Gutenberg-Universität, Mainz, Germany.

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September 2008

Linked analysis of large cooperative, allosteric systems: the case of the giant HBL hemoglobins.

Methods Enzymol 2008 ;436:463-85

Institute for Molecular Biophysics, Johannes Gutenberg University, Mainz, Germany.

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May 2008

Kinetic properties of catecholoxidase activity of tarantula hemocyanin.

FEBS J 2008 Apr 15;275(7):1518-28. Epub 2008 Feb 15.

Institut für Molekulare Biophysik, Johannes Gutenberg Universität, Mainz, Germany.

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April 2008

Switch between tyrosinase and catecholoxidase activity of scorpion hemocyanin by allosteric effectors.

FEBS Lett 2008 Mar 5;582(5):749-54. Epub 2008 Feb 5.

Institut für Molekulare Biophysik der Johannes Gutenberg Universität Mainz, Jakob-Welder-Weg 26, Mainz, Germany.

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March 2008

Hemocyanin conformational changes associated with SDS-induced phenol oxidase activation.

Biochim Biophys Acta 2007 Nov 30;1774(11):1380-94. Epub 2007 Aug 30.

School of Biological and Environmental Sciences, University of Stirling, Stirling FK9 4LA, Scotland, UK.

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November 2007

The integrative and evolutionary biology of gas-binding copper proteins: an introduction.

Integr Comp Biol 2007 Oct 23;47(4):628-30. Epub 2007 Jul 23.

*Johannes Gutenberg University Mainz, Germany; University of Oregon, OR, USA; Alfred Wegner Institut, Bremerhaven, Germany.

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October 2007

Minireview: Recent progress in hemocyanin research.

Integr Comp Biol 2007 Oct 27;47(4):631-44. Epub 2007 Jul 27.

*Institute for Molecular Biophysics, Johannes Gutenberg University, 55099 Mainz, Germany; Institute of Zoology, Johannes Gutenberg University, 55099 Mainz, Germany.

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October 2007

Negative cooperativity in Root-effect hemoglobins: role of heterogeneity.

Integr Comp Biol 2007 Oct 20;47(4):656-61. Epub 2007 Aug 20.

Institute for Molecular Biophysics, Johannes Gutenberg University, Mainz, Germany.

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October 2007

Hemocyanin from E. californicum encapsulated in silica gels: oxygen binding and conformational states.

Gene 2007 Aug 25;398(1-2):202-7. Epub 2007 Apr 25.

Department of Biochemistry and Molecular Biology, University of Parma, Parma, Italy.

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August 2007

Similar enzyme activation and catalysis in hemocyanins and tyrosinases.

Gene 2007 Aug 13;398(1-2):183-91. Epub 2007 May 13.

Institut für Molekulare Biophysik, Johannes Gutenberg Universität, 55099 Mainz, Germany.

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August 2007

MRI of tarantulas: morphological and perfusion imaging.

Magn Reson Imaging 2007 Jan 14;25(1):129-35. Epub 2006 Nov 14.

Section of Medical Physics, Department of Diagnostic and Interventional Radiology, Johannes Gutenberg University Hospital, 55131 Mainz, Germany.

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January 2007

Immobilization and AFM of single 4 x 6-mer tarantula hemocyanin molecules.

Micron 2006 31;37(8):735-41. Epub 2006 Mar 31.

Institute for Physical Chemistry, University Mainz, Germany.

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November 2006

Evidence that clustered phosphocholine head groups serve as sites for binding and assembly of an oligomeric protein pore.

J Biol Chem 2006 Sep 9;281(36):26014-21. Epub 2006 Jul 9.

Institute of Medical Microbiology and Hygiene, Hochhaus am Augustusplatz, D-55101 Mainz, Germany.

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September 2006

The first crystal structure of tyrosinase: all questions answered?

Angew Chem Int Ed Engl 2006 Jul;45(28):4546-50

Institut für Molekulare Biophysik, Johannes Gutenberg-Universität, 55099 Mainz, Germany.

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July 2006

Bacterial tyrosinases.

Syst Appl Microbiol 2006 Jan 6;29(1):3-14. Epub 2005 Sep 6.

Institute for Microbiology and Wine Research, University of Mainz, Becherweg 15, D-55099 Mainz, Germany.

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January 2006

Allosteric models for multimeric proteins: oxygen-linked effector binding in hemocyanin.

Biochemistry 2005 Aug;44(30):10328-38

Institut für Zoophysiologie, Heinrich-Heine Universität, Universitätsstrasse 1, 40225 Düsseldorf, Germany.

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August 2005

Localization of the N-terminal domain in light-harvesting chlorophyll a/b protein by EPR measurements.

J Biol Chem 2005 May 8;280(19):18623-30. Epub 2005 Mar 8.

Max-Planck-Institut für Polymerforschung, Postfach 3148, 55021 Mainz, Germany.

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May 2005

Cooperative transition in the conformation of 24-mer tarantula hemocyanin upon oxygen binding.

J Biol Chem 2005 Apr 28;280(13):12391-6. Epub 2005 Jan 28.

Department of Physical Chemistry, Johannes Gutenberg University, Mainz, Welderweg 11, 55099 Mainz, Germany.

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April 2005

Fluorescence labels as sensors for oxygen binding of arthropod hemocyanins.

Biochem Biophys Res Commun 2004 Nov;324(2):893-900

Institute for Physical Chemistry, Johannes Gutenberg University, Mainz, Germany.

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November 2004

Structure-based calculation of multi-donor multi-acceptor fluorescence resonance energy transfer in the 4x6-mer tarantula hemocyanin.

Eur Biophys J 2004 Aug 4;33(5):386-95. Epub 2003 Dec 4.

Institute for Molecular Biophysics, Johannes Gutenberg University, Jakob Welder Weg 26, 55128 Mainz, Germany.

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August 2004

Recent findings on phenoloxidase activity and antimicrobial activity of hemocyanins.

Dev Comp Immunol 2004 Jun;28(7-8):673-87

Institut für Molekulare Biophysik, Johannes Gutenberg-Universität, 55099 Mainz, Germany.

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June 2004

Small-angle scattering techniques for analyzing conformational transitions in hemocyanins.

Methods Enzymol 2004 ;379:81-106

Institute for Molecular Biophysics, Johannes Gutenberg University, Mainz, Germany.

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May 2004

Modeling techniques for analysing conformational transitions in hemocyanins by small-angle scattering of X-rays and neutrons.

Micron 2004 ;35(1-2):11-3

Institute for Molecular Biophysics, University of Mainz, Jakob Welder Weg 26, D-55128 Mainz, Germany.

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April 2004

Tarantula hemocyanins imaged by atomic force microscopy.

Micron 2004 ;35(1-2):15-6

Institut für Molekulare Biophysik, Johannes Gutenberg-Universität, Mainz 55099, Germany.

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April 2004

The Root effect--a physiological perspective.

Micron 2004 ;35(1-2):73-4

Department of Zoology and Limnology, University of Innsbruck, A-6020 Innsbruck, Austria.

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April 2004

Conversion of crustacean hemocyanin to catecholoxidase.

Micron 2004 ;35(1-2):89-90

Institut für Molekulare Biophysik, Johannes Gutenberg-Universität, 55099 Mainz, Germany.

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April 2004

Homology modelling of hemocyanins and tyrosinases: pitfalls in automated approaches.

Micron 2004 ;35(1-2):97-8

Institut für Molekulare Biophysik, Johannes Gutenberg-Universität, Mainz 55099, Germany.

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April 2004

Urate as effector for crustacean hemocyanins.

Micron 2004 ;35(1-2):109-10

Institute for Molecular Biophysics, University of Mainz, D-55099 Mainz, Germany.

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April 2004

Toward oxygen binding curves of single respiratory proteins.

Micron 2004 ;35(1-2):111-3

Institute for Physical Chemistry, University of Mainz, Welderweg 11, Mainz 55128, Germany.

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April 2004

Functional changes in the family of type 3 copper proteins during evolution.

Chembiochem 2004 Feb;5(2):163-9

Institut für Molekulare Biophysik, Johannes Gutenberg-Universität, Jakob Welder Weg 26, 55128 Mainz, Germany.

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February 2004

Small-angle X-ray scattering-based three-dimensional reconstruction of the immunogen KLH1 reveals different oxygen-dependent conformations.

J Biol Chem 2004 Jan 22;279(4):2841-5. Epub 2003 Oct 22.

Institut für Molekulare Biophysik, Universität Mainz, D-55099 Mainz, Germany.

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January 2004

A respiratory hemocyanin from an insect.

Proc Natl Acad Sci U S A 2004 Jan 8;101(3):871-4. Epub 2004 Jan 8.

Institutes of Zoology and Molecular Biophysics, Johannes Gutenberg University of Mainz, 55099 Mainz, Germany.

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January 2004

Isolation and characterization of haemoporin, an abundant haemolymph protein from Aplysia californica.

Biochem J 2003 Nov;375(Pt 3):681-8

Institut für Molekulare Biophysik, Johannes Gutenberg-Universität, 55099 Mainz, Germany.

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November 2003

Nested allosteric interactions in extracellular hemoglobin of the leech Macrobdella decora.

J Biol Chem 2003 Nov 27;278(45):44355-60. Epub 2003 Aug 27.

Institute for Molecular Biophysics, University of Mainz, Jakob-Welder-Weg 26, 55128 Mainz, Germany.

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November 2003

Effects of ultrahigh dilutions of 3,5-dichlorophenol on the luminescence of the bacterium Vibrio fischeri.

Biochim Biophys Acta 2003 Jun;1621(3):253-60

Forschungsinstitut Kwalis gGmbH, Fuldaer Str. 21, Dipperz 36160, Germany.

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June 2003

Tyrosinases from crustaceans form hexamers.

Biochem J 2003 Apr;371(Pt 2):515-23

Institut für Molekulare Biophysik, Johannes Gutenberg Universität Mainz, Jakob Welder Weg 26, D-55128 Mainz, Germany.

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April 2003

All hierarchical levels are involved in conformational transitions of the 4 x 6-meric tarantula hemocyanin upon oxygenation.

Biochim Biophys Acta 2002 Dec;1601(2):132-7

Institut für Molekulare Biophysik, Universität Mainz, Jakob Welder Weg 26, D-55099 Mainz, Germany.

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December 2002

Nested MWC model describes hydrolysis of GroEL without assuming negative cooperativity in binding.

Biochim Biophys Acta 2002 Sep;1599(1-2):45-55

Institute for Molecular Biophysics, University of Mainz, Germany.

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September 2002

Potential active-site residues in polyneuridine aldehyde esterase, a central enzyme of indole alkaloid biosynthesis, by modelling and site-directed mutagenesis.

Eur J Biochem 2002 Jun;269(12):2889-96

Lehrstuhl für Pharmazeutische Biologie, Institut für Pharmazie, Johannes Gutenberg-Universität Mainz, Germany.

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June 2002