Heinrich Sticht

Heinrich Sticht

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Heinrich Sticht

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Loss of function of SVBP leads to autosomal recessive intellectual disability, microcephaly, ataxia, and hypotonia.

Genet Med 2019 08 4;21(8):1790-1796. Epub 2019 Jan 4.

Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

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http://dx.doi.org/10.1038/s41436-018-0415-8DOI Listing
August 2019

A Metadynamics-Based Protocol for the Determination of GPCR-Ligand Binding Modes.

Int J Mol Sci 2019 Apr 22;20(8). Epub 2019 Apr 22.

Bioinformatik, Institut für Biochemie, Emil-Fischer-Centrum, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Fahrstraße 17, 91054 Erlangen, Germany.

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http://dx.doi.org/10.3390/ijms20081970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514967PMC
April 2019

enters gut epithelial cells and impairs intestinal barrier function through cleavage of occludin by serine protease HtrA.

Gut Pathog 2019 13;11. Epub 2019 Feb 13.

1Division of Microbiology, Dept. of Biology, University of Erlangen-Nuremberg, Staudtstr. 5, 91058 Erlangen, Germany.

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http://dx.doi.org/10.1186/s13099-019-0283-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373145PMC
February 2019

Binding of histamine to the H1 receptor-a molecular dynamics study.

J Mol Model 2018 Nov 29;24(12):346. Epub 2018 Nov 29.

Bioinformatik, Institut für Biochemie, Emil-Fischer-Centrum, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), , Fahrstraße 17, 91054, Erlangen, Germany.

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http://dx.doi.org/10.1007/s00894-018-3873-7DOI Listing
November 2018

IFN-γ-response mediator GBP-1 represses human cell proliferation by inhibiting the Hippo signaling transcription factor TEAD.

Biochem J 2018 09 25;475(18):2955-2967. Epub 2018 Sep 25.

Division of Molecular and Experimental Surgery, Translational Research Center, Department of Surgery, University Medical Center Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Schwabachanlage 12, 91054 Erlangen, Germany

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http://biochemj.org/lookup/doi/10.1042/BCJ20180123
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http://dx.doi.org/10.1042/BCJ20180123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156764PMC
September 2018

Conformational Dynamics of Herpesviral NEC Proteins in Different Oligomerization States.

Int J Mol Sci 2018 Sep 25;19(10). Epub 2018 Sep 25.

Division of Bioinformatics, Institute of Biochemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Fahrstraße 17, 91054 Erlangen, Germany.

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http://dx.doi.org/10.3390/ijms19102908DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213152PMC
September 2018

The degenerin region of the human bile acid-sensitive ion channel (BASIC) is involved in channel inhibition by calcium and activation by bile acids.

Pflugers Arch 2018 07 27;470(7):1087-1102. Epub 2018 Mar 27.

Institut für Zelluläre und Molekulare Physiologie, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Waldstr. 6, 91054, Erlangen, Germany.

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http://link.springer.com/10.1007/s00424-018-2142-z
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http://dx.doi.org/10.1007/s00424-018-2142-zDOI Listing
July 2018

Analysis of naturally occurring mutations in the human uptake transporter NaCT important for bone and brain development and energy metabolism.

Sci Rep 2018 07 27;8(1):11330. Epub 2018 Jul 27.

Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Fahrstrasse 17, 91054, Erlangen, Germany.

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http://dx.doi.org/10.1038/s41598-018-29547-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063891PMC
July 2018

Probing the role of intercalating protein sidechains for kink formation in DNA.

PLoS One 2018 12;13(2):e0192605. Epub 2018 Feb 12.

Bioinformatik, Institut für Biochemie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0192605PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809078PMC
April 2018

Amino-Terminal Processing of Serine Protease HtrA: Role in Oligomerization and Activity Regulation.

Front Microbiol 2018 16;9:642. Epub 2018 Apr 16.

Division of Microbiology, Department of Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

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http://journal.frontiersin.org/article/10.3389/fmicb.2018.00
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http://dx.doi.org/10.3389/fmicb.2018.00642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911493PMC
April 2018

Interaction of Glycolipids with the Macrophage Surface Receptor Mincle - a Systematic Molecular Dynamics Study.

Sci Rep 2018 03 29;8(1):5374. Epub 2018 Mar 29.

Bioinformatik, Institut für Biochemie, Emil-Fischer-Centrum, Friedrich-Alexander-Universität Erlangen-Nürnberg, (FAU), Fahrstraße 17, 91054, Erlangen, Germany.

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http://dx.doi.org/10.1038/s41598-018-23624-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876379PMC
March 2018

Structure-based functional analysis of effector protein SifA in living cells reveals motifs important for Salmonella intracellular proliferation.

Int J Med Microbiol 2018 Jan 8;308(1):84-96. Epub 2017 Sep 8.

Abt. Mikrobiologie, Universität Osnabrück, Osnabrück, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ijmm.2017.09.004DOI Listing
January 2018

Confirmation of mutations in as a novel cause of vitamin B -dependent epilepsy.

J Med Genet 2017 12 8;54(12):809-814. Epub 2017 Apr 8.

radiz - "Rare Disease Initiative Zurich, Clinical Research Priority Program for Rare Diseases University of Zurich", University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1136/jmedgenet-2017-104521DOI Listing
December 2017

Dynamic regulatory interaction between cytomegalovirus major tegument protein pp65 and protein kinase pUL97 in intracellular compartments, dense bodies and virions.

J Gen Virol 2017 11 12;98(11):2850-2863. Epub 2017 Oct 12.

1​Institute for Clinical and Molecular Virology, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen, Germany.

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http://dx.doi.org/10.1099/jgv.0.000939DOI Listing
November 2017

Role of the N-terminus for the stability of an amyloid-β fibril with three-fold symmetry.

PLoS One 2017 12;12(10):e0186347. Epub 2017 Oct 12.

Bioinformatik, Institut für Biochemie, Emil-Fischer-Centrum, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0186347PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638522PMC
October 2017

Genotype-phenotype evaluation of MED13L defects in the light of a novel truncating and a recurrent missense mutation.

Eur J Med Genet 2017 Sep 21;60(9):451-464. Epub 2017 Jun 21.

Institute of Medical Genetics, University of Zurich, Schlieren-Zurich, Switzerland; Neuroscience Center Zurich, University of Zurich, Zurich, Switzerland; Zurich Center of Integrative Human Physiology, University of Zurich, Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.ejmg.2017.06.004DOI Listing
September 2017

Probing the potential of CnaB-type domains for the design of tag/catcher systems.

PLoS One 2017 27;12(6):e0179740. Epub 2017 Jun 27.

Bioinformatik, Institut für Biochemie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0179740PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487036PMC
September 2017

Protective capacity of neutralizing and non-neutralizing antibodies against glycoprotein B of cytomegalovirus.

PLoS Pathog 2017 Aug 30;13(8):e1006601. Epub 2017 Aug 30.

Virologisches Institut, Klinische und Molekulare Virologie, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany.

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http://dx.doi.org/10.1371/journal.ppat.1006601DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595347PMC
August 2017

The human cytomegalovirus nuclear egress complex unites multiple functions: Recruitment of effectors, nuclear envelope rearrangement, and docking to nuclear capsids.

Rev Med Virol 2017 07 30;27(4). Epub 2017 Jun 30.

Institute for Clinical and Molecular Virology, Friedrich-Alexander University of Erlangen-Nürnberg (FAU), Erlangen, Germany.

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http://dx.doi.org/10.1002/rmv.1934DOI Listing
July 2017

Crystal Structure of the Extracellular Domain of the Human Dendritic Cell Surface Marker CD83.

J Mol Biol 2017 04 15;429(8):1227-1243. Epub 2017 Mar 15.

Division of Biotechnology, Department of Biology, Friedrich-Alexander-University Erlangen-Nürnberg, Henkestr. 91, D-91052 Erlangen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2017.03.009DOI Listing
April 2017

Hypomorphic Pathogenic Variants in TAF13 Are Associated with Autosomal-Recessive Intellectual Disability and Microcephaly.

Am J Hum Genet 2017 Mar;100(3):555-561

Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91054 Erlangen, Germany; Institute of Human Genetics, University Medical Center Leipzig, 04103 Leipzig, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2017.01.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339287PMC
March 2017

A Homozygous Mutation in GPT2 Associated with Nonsyndromic Intellectual Disability in a Consanguineous Family from Costa Rica.

JIMD Rep 2017 28;36:59-66. Epub 2017 Jan 28.

Section of Genetics and Biotechnology, School of Biology, University of Costa Rica, 11501-2060, San Jose, Costa Rica.

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http://dx.doi.org/10.1007/8904_2016_40DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680285PMC
January 2017

Analysis of amino acid residues in the predicted transmembrane pore influencing transport kinetics of the hepatic drug transporter organic anion transporting polypeptide 1B1 (OATP1B1).

Biochim Biophys Acta 2016 Nov 1;1858(11):2894-2902. Epub 2016 Sep 1.

Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Fahrstrasse 17, 91054 Erlangen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbamem.2016.08.018DOI Listing
November 2016

Probing the Structure of the Escherichia coli Periplasmic Proteins HdeA and YmgD by Molecular Dynamics Simulations.

J Phys Chem B 2016 11 9;120(46):11845-11855. Epub 2016 Nov 9.

Division of Bioinformatics, Institute of Biochemistry, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) , Fahrstraße 17, 91054 Erlangen, Germany.

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http://pubs.acs.org/doi/10.1021/acs.jpcb.6b06091
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http://dx.doi.org/10.1021/acs.jpcb.6b06091DOI Listing
November 2016

Systematic analysis of phosphotyrosine antibodies recognizing single phosphorylated EPIYA-motifs in CagA of East Asian-type Helicobacter pylori strains.

BMC Microbiol 2016 09 2;16(1):201. Epub 2016 Sep 2.

Department of Biology, Division of Microbiology, Friedrich Alexander University Erlangen-Nuremberg, Staudtstr. 5, D-91058, Erlangen, Germany.

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http://dx.doi.org/10.1186/s12866-016-0820-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009636PMC
September 2016

SPATA5 mutations cause a distinct autosomal recessive phenotype of intellectual disability, hypotonia and hearing loss.

Orphanet J Rare Dis 2016 Sep 29;11(1):130. Epub 2016 Sep 29.

Institute of Human Genetics, Friedrich-Alexander-University Erlangen-Nuremberg, 91054, Erlangen, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041579PMC
http://dx.doi.org/10.1186/s13023-016-0509-9DOI Listing
September 2016

Modulation of Recombinant Human α1 Glycine Receptors by Mono- and Disaccharides: A Kinetic Study.

ACS Chem Neurosci 2016 08 9;7(8):1077-87. Epub 2016 Jun 9.

Department of Biochemistry, The German University in Cairo , Main Entrance of Al Tagamoa Al Khames, New Cairo 11835, Egypt.

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http://dx.doi.org/10.1021/acschemneuro.6b00044DOI Listing
August 2016

The pH-dependent Client Release from the Collagen-specific Chaperone HSP47 Is Triggered by a Tandem Histidine Pair.

J Biol Chem 2016 Jun 19;291(24):12612-26. Epub 2016 Apr 19.

From the Institute of Biochemistry, University of Cologne, Otto-Fischer-Strasse 12-14, D-50674 Cologne, Germany,

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http://dx.doi.org/10.1074/jbc.M115.706069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933464PMC
June 2016

Investigation of the dynamics of the viral immediate-early protein 1 in different conformations and oligomerization states.

J Biomol Struct Dyn 2016 May 24;34(5):1029-41. Epub 2015 Jul 24.

a Bioinformatik, Institut für Biochemie , Friedrich-Alexander-Universität, Erlangen-Nürnberg , Fahrstraße 17, D-91054 Erlangen , Germany.

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http://dx.doi.org/10.1080/07391102.2015.1065204DOI Listing
May 2016

11th German Conference on Chemoinformatics (GCC 2015) : Fulda, Germany. 8-10 November 2015.

Authors:
Uli Fechner Chris de Graaf Andrew E Torda Stefan Güssregen Andreas Evers Hans Matter Gerhard Hessler Nicola J Richmond Peter Schmidtke Marwin H S Segler Mark P Waller Stefanie Pleik Joan-Emma Shea Zachary Levine Ryan Mullen Karina van den Broek Matthias Epple Hubert Kuhn Andreas Truszkowski Achim Zielesny Johannes Hans Fraaije Ruben Serral Gracia Stefan M Kast Krishna C Bulusu Andreas Bender Abraham Yosipof Oren Nahum Hanoch Senderowitz Timo Krotzky Robert Schulz Gerhard Wolber Stefan Bietz Matthias Rarey Markus O Zimmermann Andreas Lange Manuel Ruff Johannes Heidrich Ionut Onlia Thomas E Exner Frank M Boeckler Marcel Bermudez Dzmitry S Firaha Oldamur Hollóczki Barbara Kirchner Christofer S Tautermann Andrea Volkamer Sameh Eid Samo Turk Friedrich Rippmann Simone Fulle Noureldin Saleh Giorgio Saladino Francesco L Gervasio Elke Haensele Lee Banting David C Whitley Jana Sopkova-de Oliveira Santos Ronan Bureau Timothy Clark Achim Sandmann Harald Lanig Patrick Kibies Jochen Heil Franziska Hoffgaard Roland Frach Julian Engel Steven Smith Debjit Basu Daniel Rauh Oliver Kohlbacher Frank M Boeckler Jonathan W Essex Michael S Bodnarchuk Gregory A Ross Arndt R Finkelmann Andreas H Göller Gisbert Schneider Tamara Husch Christoph Schütter Andrea Balducci Martin Korth Fidele Ntie-Kang Stefan Günther Wolfgang Sippl Luc Meva'a Mbaze Fidele Ntie-Kang Conrad V Simoben Lydia L Lifongo Fidele Ntie-Kang Philip Judson Jiří Barilla Miloš V Lokajíček Hana Pisaková Pavel Simr Natalia Kireeva Alexandre Petrov Denis Ostroumov Vitaly P Solovev Vladislav S Pervov Nils-Ole Friedrich Kai Sommer Matthias Rarey Johannes Kirchmair Eugen Proschak Julia Weber Daniel Moser Lena Kalinowski Janosch Achenbach Mark Mackey Tim Cheeseright Gerrit Renner Gerrit Renner Torsten C Schmidt Jürgen Schram Marion Egelkraut-Holtus Albert van Oeyen Tuomo Kalliokoski Denis Fourches Akachukwu Ibezim Chika J Mbah Umale M Adikwu Ngozi J Nwodo Alexander Steudle Brian B Masek Stephan Nagy David Baker Fred Soltanshahi Roman Dorfman Karen Dubrucq Hitesh Patel Oliver Koch Florian Mrugalla Stefan M Kast Qurrat U Ain Julian E Fuchs Robert M Owen Kiyoyuki Omoto Rubben Torella David C Pryde Robert Glen Andreas Bender Petr Hošek Vojtěch Spiwok Lewis H Mervin Ian Barrett Mike Firth David C Murray Lisa McWilliams Qing Cao Ola Engkvist Dawid Warszycki Marek Śmieja Andrzej J Bojarski Natalia Aniceto Alex Freitas Taravat Ghafourian Guido Herrmann Valentina Eigner-Pitto Alexandra Naß Rafał Kurczab Andrzej J Bojarski Andreas Lange Marcel B Günther Susanne Hennig Felix M Büttner Christoph Schall Adrian Sievers-Engler Francesco Ansideri Pierre Koch Thilo Stehle Stefan Laufer Frank M Böckler Barbara Zdrazil Floriane Montanari Gerhard F Ecker Christoph Grebner Anders Hogner Johan Ulander Karl Edman Victor Guallar Christian Tyrchan Johan Ulander Christian Tyrchan Wolfgang Klute Fredrik Bergström Christian Kramer Quoc Dat Nguyen Roland Frach Patrick Kibies Steven Strohfeldt Saraphina Böttcher Tim Pongratz Dominik Horinek Stefan M Kast Bernd Rupp Raed Al-Yamori Michael Lisurek Ronald Kühne Filipe Furtado Karina van den Broek Ludger Wessjohann Miriam Mathea Knut Baumann Siti Zuraidah Mohamad-Zobir Xianjun Fu Tai-Ping Fan Andreas Bender Maximilian A Kuhn Christoph A Sotriffer Azedine Zoufir Xitong Li Lewis Mervin Ellen Berg Mark Polokoff Wolf D Ihlenfeldt Wolf D Ihlenfeldt Jette Pretzel Zayan Alhalabi Robert Fraczkiewicz Marvin Waldman Robert D Clark Neem Shaikh Prabha Garg Alexander Kos Hans-Jürgen Himmler Achim Sandmann Christophe Jardin Heinrich Sticht Thomas B Steinbrecher Markus Dahlgren Daniel Cappel Teng Lin Lingle Wang Goran Krilov Robert Abel Richard Friesner Woody Sherman Ina A Pöhner Joanna Panecka Rebecca C Wade Stefan Bietz Karen T Schomburg Matthias Hilbig Matthias Rarey Christian Jäger Vivien Wieczorek Lance M Westerhoff Oleg Y Borbulevych Hans-Ulrich Demuth Mirko Buchholz Denis Schmidt Thomas Rickmeyer Timo Krotzky Peter Kolb Sumit Mittal Elsa Sánchez-García Mauro S Nogueira Tiago B Oliveira Fernando B da Costa Thomas J Schmidt

J Cheminform 2016 Apr 26;8(Suppl 1):18. Epub 2016 Apr 26.

Central Institute for Scientific Computing (ZISC), FAU-Erlangen-Nürnberg, Martensstr. 5a, 91058, Erlangen, Germany.

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http://dx.doi.org/10.1186/s13321-016-0119-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896257PMC
April 2016

Mimicking titration experiments with MD simulations: A protocol for the investigation of pH-dependent effects on proteins.

Sci Rep 2016 Mar 3;6:22523. Epub 2016 Mar 3.

Division of Bioinformatics, Institute of Biochemistry, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Fahrstraße 17, 91054 Erlangen, Germany.

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http://www.nature.com/articles/srep22523
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http://dx.doi.org/10.1038/srep22523DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776130PMC
March 2016

Synthetic Peptides as Protein Mimics.

Front Bioeng Biotechnol 2015 19;3:211. Epub 2016 Jan 19.

Department of Chemistry and Pharmacy, University of Erlangen-Nuremberg , Erlangen , Germany.

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http://journal.frontiersin.org/Article/10.3389/fbioe.2015.00
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http://dx.doi.org/10.3389/fbioe.2015.00211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717299PMC
February 2016

N(8)-acetylspermidine as a potential plasma biomarker for Snyder-Robinson syndrome identified by clinical metabolomics.

J Inherit Metab Dis 2016 Jan 15;39(1):131-7. Epub 2015 Jul 15.

Division of Child Neurology, University Children's Hospital Zurich, Steinwiesstrasse 75, 8032, Zurich, Switzerland.

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http://dx.doi.org/10.1007/s10545-015-9876-yDOI Listing
January 2016

Synthetic Protein Scaffolds Based on Peptide Motifs and Cognate Adaptor Domains for Improving Metabolic Productivity.

Front Bioeng Biotechnol 2015 23;3:191. Epub 2015 Nov 23.

Bioinformatik, Institut für Biochemie, Friedrich-Alexander-Universität Erlangen-Nürnberg , Erlangen , Germany.

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http://dx.doi.org/10.3389/fbioe.2015.00191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655305PMC
December 2015

A severe congenital myasthenic syndrome with "dropped head" caused by novel MUSK mutations.

Muscle Nerve 2015 Oct 1;52(4):668-73. Epub 2015 Jun 1.

Department of Paediatric Neurology, University Children's Hospital, Steinwiesstrasse 75, 8032, Zürich, Switzerland.

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http://dx.doi.org/10.1002/mus.24687DOI Listing
October 2015

The Interaction between Cyclin B1 and Cytomegalovirus Protein Kinase pUL97 is Determined by an Active Kinase Domain.

Viruses 2015 Aug 11;7(8):4582-601. Epub 2015 Aug 11.

Institute for Clinical and Molecular Virology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.

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http://dx.doi.org/10.3390/v7082834DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576195PMC
August 2015

Responsiveness of B cells is regulated by the hinge region of IgD.

Nat Immunol 2015 May 6;16(5):534-43. Epub 2015 Apr 6.

1] Institute of Immunology, University Hospital Ulm, Ulm, Germany. [2] BIOSS Center for Biological Signaling Studies, Albert-Ludwigs University of Freiburg, Freiburg, Germany. [3] Department of Molecular Immunology, Biology III, Faculty of Biology, Albert-Ludwigs University of Freiburg, Freiburg, Germany.

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http://www.nature.com/articles/ni.3141
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http://dx.doi.org/10.1038/ni.3141DOI Listing
May 2015

Binding properties of SUMO-interacting motifs (SIMs) in yeast.

J Mol Model 2015 Mar 19;21(3):50. Epub 2015 Feb 19.

Bioinformatik, Institut für Biochemie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Fahrstr. 17, 91054, Erlangen, Germany.

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http://dx.doi.org/10.1007/s00894-015-2597-1DOI Listing
March 2015

CD83 and GRASP55 interact in human dendritic cells.

Biochem Biophys Res Commun 2015 Mar 19;459(1):42-8. Epub 2015 Feb 19.

Department of Immune Modulation, Universitätsklinikum Erlangen, Erlangen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2015.02.057DOI Listing
March 2015

A specific A/T polymorphism in Western tyrosine phosphorylation B-motifs regulates Helicobacter pylori CagA epithelial cell interactions.

PLoS Pathog 2015 Feb 3;11(2):e1004621. Epub 2015 Feb 3.

Departments of Medicine and Microbiology, New York University School of Medicine and VA Medical Center, New York, New York, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1004621DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412286PMC
February 2015

Identification of a neutralizing epitope within antigenic domain 5 of glycoprotein B of human cytomegalovirus.

J Virol 2015 Jan 15;89(1):361-72. Epub 2014 Oct 15.

Institut für Klinische und Molekulare Virologie, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany

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http://jvi.asm.org/lookup/doi/10.1128/JVI.02393-14
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http://dx.doi.org/10.1128/JVI.02393-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301166PMC
January 2015

DAPK-HSF1 interaction as a positive-feedback mechanism stimulating TNF-induced apoptosis in colorectal cancer cells.

J Cell Sci 2014 Dec 6;127(Pt 24):5273-87. Epub 2014 Nov 6.

Department of Experimental Tumor Pathology, Institute of Pathology, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Erlangen 91054, Germany

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http://dx.doi.org/10.1242/jcs.157024DOI Listing
December 2014

NDST1 missense mutations in autosomal recessive intellectual disability.

Am J Med Genet A 2014 Nov 14;164A(11):2753-63. Epub 2014 Aug 14.

Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

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http://dx.doi.org/10.1002/ajmg.a.36723DOI Listing
November 2014

Single expressed glycine receptor domains reconstitute functional ion channels without subunit-specific desensitization behavior.

J Biol Chem 2014 Oct 20;289(42):29135-47. Epub 2014 Aug 20.

Institute of Biochemistry, Emil Fischer Center, Friedrich-Alexander University Erlangen-Nürnberg, Fahrstrasse 17, 91054 Erlangen, Germany, the Institute for Clinical Neurobiology, University of Würzburg, Versbacherstrasse 5, 97078 Würzburg, Germany, and

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http://dx.doi.org/10.1074/jbc.M114.559138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200267PMC
October 2014

Structural basis for the recognition of human cytomegalovirus glycoprotein B by a neutralizing human antibody.

PLoS Pathog 2014 Oct 9;10(10):e1004377. Epub 2014 Oct 9.

Lehrstuhl für Biotechnik, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany.

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http://dx.doi.org/10.1371/journal.ppat.1004377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192593PMC
October 2014

Infantile epileptic encephalopathy, transient choreoathetotic movements, and hypersomnia due to a De Novo missense mutation in the SCN2A gene.

Neuropediatrics 2014 Aug 7;45(4):261-4. Epub 2014 Apr 7.

Division of Neurology, Department of Pediatrics, University Children's Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1055/s-0034-1372302DOI Listing
August 2014

Gene dosage-dependent rescue of HSP neurite defects in SPG4 patients' neurons.

Hum Mol Genet 2014 May 30;23(10):2527-41. Epub 2013 Dec 30.

IZKF Junior Research Group and BMBF Research Group Neuroscience, IZKF, Friedrich-Alexander University Erlangen-Nuernberg (FAU), Glückstr. 6, Erlangen 91054, Germany.

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http://dx.doi.org/10.1093/hmg/ddt644DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990156PMC
May 2014

Mutations in herpes simplex virus gD protein affect receptor binding by different molecular mechanisms.

J Mol Model 2014 Apr 20;20(4):2192. Epub 2014 Mar 20.

Bioinformatik, Institut für Biochemie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Fahrstraße 17, 91054, Erlangen, Germany.

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http://dx.doi.org/10.1007/s00894-014-2192-xDOI Listing
April 2014

The conformational stability of nonfibrillar amyloid-β peptide oligomers critically depends on the C-terminal peptide length.

ACS Chem Neurosci 2014 Mar 11;5(3):161-7. Epub 2014 Feb 11.

Bioinformatik, Institut für Biochemie, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) , Fahrstraße 17, 91054 Erlangen, Germany.

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http://dx.doi.org/10.1021/cn400208rDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963130PMC
March 2014

The cyclin-dependent kinase ortholog pUL97 of human cytomegalovirus interacts with cyclins.

Viruses 2013 Dec 18;5(12):3213-30. Epub 2013 Dec 18.

Institute for Clinical and Molecular Virology, University of Erlangen-Nuremberg, 91054 Erlangen, Germany.

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http://dx.doi.org/10.3390/v5123213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967168PMC
December 2013