Heikki Swan

Heikki Swan

UNVERIFIED PROFILE

Are you Heikki Swan?   Register this Author

Register author
Heikki Swan

Heikki Swan

Publications by authors named "Heikki Swan"

Are you Heikki Swan?   Register this Author

76Publications

1135Reads

7Profile Views

The Role of Mutations and Maternal Beta Blocker Use During Pregnancy in the Growth of Children With Long QT Syndrome.

Front Endocrinol (Lausanne) 2018 24;9:194. Epub 2018 Apr 24.

Department of Physiology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fendo.2018.00194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928157PMC
April 2018

The genetics underlying idiopathic ventricular fibrillation: A special role for catecholaminergic polymorphic ventricular tachycardia?

Int J Cardiol 2018 Jan 5;250:139-145. Epub 2017 Oct 5.

Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, IRCCS Istituto Auxologico Italiano, Milan, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijcard.2017.10.016DOI Listing
January 2018

Type 1 long QT syndrome and psychological stress in a laboratory setting.

J Health Psychol 2018 Jan 1:1359105317751617. Epub 2018 Jan 1.

1 University of Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1359105317751617DOI Listing
January 2018

Is Symptomatic Long QT Syndrome Associated with Depression in Women and Men?

J Genet Couns 2017 Jun 23;26(3):491-500. Epub 2016 Aug 23.

Institute of Behavioral Sciences, University of Helsinki, Siltavuorenpenger 1 A, P.O. Box 9, 00014, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10897-016-0004-4DOI Listing
June 2017

Genetic Modifiers for the Long-QT Syndrome: How Important Is the Role of Variants in the 3' Untranslated Region of KCNQ1?

Circ Cardiovasc Genet 2016 Aug;9(4):330-9

From the Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, IRCCS Istituto Auxologico Italiano, Milan (L.C., C.S., P.J.S.); Department of Molecular Medicine (L.C.) and Department of Public Health (M.C.M., C.M.), Unit of Biostatistics and Clinical Epidemiology, University of Pavia, Pavia; Department of Cardiovascular, Neural and Metabolic Sciences, San Luca Hospital IRCCS Istituto Auxologico Italiano, Milan, Italy (L.C., G.P.); Department of Medicine, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland (A.M.L., K.K.); Institute of Human Genetics, Helmholtz Zentrum München, Neuherberg, Germany (E.M., P.L., T.M.); Department of Medicine and Surgery University of Milano-Bicocca, Milan, Italy (G.P.); Department of Internal Medicine, University of Stellenbosch, South Africa (M.H., A.G., P.A.B.); Institute of Human Genetics, Technische Universität München (T.M.); DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany (T.M.); and Heart and Lung Center, Helsinki University Central Hospital, Helsinki, Finland (H.S.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCGENETICS.116.001419DOI Listing
August 2016

Antiarrhythmic Action of Flecainide in Polymorphic Ventricular Arrhythmias Caused by a Gain-of-Function Mutation in the Nav 1.5 Sodium Channel.

Ann Noninvasive Electrocardiol 2016 Jul 7;21(4):343-51. Epub 2015 Oct 7.

Department of Clinical Research, University of Bern, Bern, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/anec.12312DOI Listing
July 2016

Antiarrhythmic Effects of Dantrolene in Patients with Catecholaminergic Polymorphic Ventricular Tachycardia and Replication of the Responses Using iPSC Models.

PLoS One 2015 8;10(5):e0125366. Epub 2015 May 8.

BioMediTech, University of Tampere, Tampere, Finland; School of Medicine, University of Tampere, Tampere, Finland; Heart Hospital, Tampere University Hospital, Tampere, Finland.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0125366PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425399PMC
February 2016

Follow-up of 316 molecularly defined pediatric long-QT syndrome patients: clinical course, treatments, and side effects.

Circ Arrhythm Electrophysiol 2015 Aug 10;8(4):815-23. Epub 2015 Jun 10.

From the Heart and Lung Center, Helsinki University Central Hospital (M.K., A.M., M.V., L.T., H.S.), Children's Hospital, Helsinki University Central Hospital (A.H., J.-M.H.), Department of Medicine, Helsinki University Central Hospital (A.M.L., K.K.), and Institute of Behavioural Sciences, Psychology (T.H.), University of Helsinki, Helsinki, Finland; and Department of Health, National Institute for Health and Welfare, Helsinki, Finland (A.S.H., V.S.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCEP.114.002654DOI Listing
August 2015

Gain-of-function mutation of the SCN5A gene causes exercise-induced polymorphic ventricular arrhythmias.

Circ Cardiovasc Genet 2014 Dec 10;7(6):771-81. Epub 2014 Sep 10.

From the Heart and Lung Center, Helsinki University Central Hospital, Helsinki, Finland (H.S., A.M., L.T.); Department of Clinical Research (M.Y.A., H.A), and Department of Physiology (J.P.K), University of Bern, Bern, Switzerland. and Institute for Molecular Medicine Finland (FIMM), University of Helsinki (J.L., A.P., E.W.), and Department of Medicine, University of Helsinki and Helsinki University Central Hospital (P.J.L.-F., A.M.L., K.K.), Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCGENETICS.114.000703DOI Listing
December 2014

Characteristics of atrial fibrillation and comorbidities in familial atrial fibrillation.

J Cardiovasc Electrophysiol 2013 Jul 29;24(7):768-74. Epub 2013 Mar 29.

Department of Cardiology, Helsinki University Central Hospital, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jce.12127DOI Listing
July 2013

[Investigation and treatment of premature beats].

Authors:
Heikki Swan

Duodecim 2013 ;129(6):599-607

HYKS, Meilahden sairaala, sydäntutkimusosasto.

View Article

Download full-text PDF

Source
July 2013

Stress proneness in molecularly defined long QT syndrome: a study using temperament assessment by behavioural inhibition system scale.

Stress Health 2013 Apr 30;29(2):150-5. Epub 2012 Aug 30.

IBS, Unit of Personality, Work and Health Psychology, University of Helsinki, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/smi.2441DOI Listing
April 2013

T-wave morphology after epinephrine bolus may reveal silent long QT syndrome mutation carriers.

J Electrocardiol 2012 Jul-Aug;45(4):368-72. Epub 2012 May 4.

Helsinki University Central Hospital, Department of Cardiology, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jelectrocard.2012.04.007DOI Listing
November 2012

[Gene tests in cardiac rhythm disturbances--new international expert recommendations].

Authors:
Heikki Swan

Duodecim 2012 ;128(7):697-704

HYKS, Meilahden sairaala, sydäntutkimusosasto.

View Article

Download full-text PDF

Source
August 2012

[Genetic testing of patients with cardiomyopathies, the resuscitated and victims of sudden death--new international expert recommendations].

Authors:
Heikki Swan

Duodecim 2012 ;128(9):937-44

HYKS, Meilahden Sairaala, Sydäntutkimusossasto.

View Article

Download full-text PDF

Source
August 2012

Intravenous epinephrine infusion test in diagnosis of catecholaminergic polymorphic ventricular tachycardia.

J Cardiovasc Electrophysiol 2012 Feb 28;23(2):194-9. Epub 2011 Sep 28.

Research Program in Molecular Medicine, University of Helsinki, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1540-8167.2011.02188.xDOI Listing
February 2012

Cloninger's temperament traits and inherited long QT syndrome.

J Psychosom Res 2011 Oct 22;71(4):245-9. Epub 2011 Apr 22.

Institute of Behavioral Sciences, Psychology, University of Helsinki, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jpsychores.2011.03.010DOI Listing
October 2011

Population-prevalent desmosomal mutations predisposing to arrhythmogenic right ventricular cardiomyopathy.

Heart Rhythm 2011 Aug 10;8(8):1214-21. Epub 2011 Mar 10.

Research Program for Molecular Medicine, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hrthm.2011.03.015DOI Listing
August 2011

Comparison of QT peak and QT end interval responses to autonomic adaptation in asymptomatic LQT1 mutation carriers.

Clin Physiol Funct Imaging 2011 May 7;31(3):209-14. Epub 2010 Dec 7.

Department of Cardiology, Laboratory of Clinical Physiology, Helsinki University Hospital, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1475-097X.2010.01002.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121965PMC
May 2011

Epinephrine bolus test in detecting long QT syndrome mutation carriers with indeterminable electrocardiographic phenotype.

Ann Noninvasive Electrocardiol 2011 Apr;16(2):172-9

Helsinki University Hospital, Department of Cardiology, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1542-474X.2011.00426.xDOI Listing
April 2011

Ryanodine receptor (RyR2) mutations in sudden cardiac death: studies in extended pedigrees and phenotypic characterization in vitro.

Int J Cardiol 2011 Mar 25;147(2):246-52. Epub 2009 Sep 25.

Research Program for Molecular Medicine, University of Helsinki, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijcard.2009.08.041DOI Listing
March 2011

Depressive symptoms in the congenital long QT syndrome.

Ann Med 2009 ;41(7):516-21

Department of Psychology, University of Helsinki, FIN-00014, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/07853890903037254DOI Listing
January 2011

KCNE1 D85N polymorphism--a sex-specific modifier in type 1 long QT syndrome?

BMC Med Genet 2011 Jan 18;12:11. Epub 2011 Jan 18.

Research Program for Molecular Medicine, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2350-12-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032654PMC
January 2011

Abnormal repolarization dynamics revealed in exercise test in long QT syndrome mutation carriers with normal resting QT interval.

Europace 2010 Sep 20;12(9):1296-301. Epub 2010 Jun 20.

Department of Cardiology, Helsinki University Hospital, Helsinki, Finland.

View Article

Download full-text PDF

Source
https://academic.oup.com/europace/article-lookup/doi/10.1093
Publisher Site
http://dx.doi.org/10.1093/europace/euq184DOI Listing
September 2010

Catecholaminergic polymorphic ventricular tachycardia.

Eur J Pediatr 2010 May 9;169(5):535-42. Epub 2010 Feb 9.

Paediatric Research Centre, Tampere University and University Hospital, FinMed-3 Building, Tampere, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00431-010-1154-2DOI Listing
May 2010

U-waves and T-wave peak to T-wave end intervals in patients with catecholaminergic polymorphic ventricular tachycardia, effects of beta-blockers.

Heart Rhythm 2008 Oct 12;5(10):1382-8. Epub 2008 Jun 12.

Department of Cardiology, Helsinki University Central Hospital, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hrthm.2008.06.011DOI Listing
October 2008

Plakophilin-2 missense mutations in arrhythmogenic right ventricular cardiomyopathy.

Int J Cardiol 2008 May 22;126(1):92-100. Epub 2007 May 22.

Research Program for Molecular Medicine, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijcard.2007.03.137DOI Listing
May 2008

The effect of antihistamine cetirizine on ventricular repolarization in congenital long QT syndrome.

J Cardiovasc Electrophysiol 2007 Jul 15;18(7):691-5. Epub 2007 May 15.

Department of Cardiology, Helsinki University Hospital, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1540-8167.2007.00844.xDOI Listing
July 2007

Beta1-adrenergic receptor polymorphisms, QTc interval and occurrence of symptoms in type 1 of long QT syndrome.

Int J Cardiol 2007 May 4;118(2):197-202. Epub 2006 Oct 4.

Department of Medicine, University of Helsinki, 00290 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijcard.2006.06.050DOI Listing
May 2007

Further evidence of inherited long QT syndrome gene mutations in antiarrhythmic drug-associated torsades de pointes.

Heart Rhythm 2007 May 18;4(5):603-7. Epub 2007 Jan 18.

Research Program in Molecular Medicine, Biomedicum Helsinki, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hrthm.2007.01.019DOI Listing
May 2007

Molecular characterization of two founder mutations causing long QT syndrome and identification of compound heterozygous patients.

Ann Med 2006 ;38(4):294-304

Biomedicum Helsinki and Department of Medicine, University of Helsinki, Finland, and Service of Cardiology, University Hospital, Lausanne, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/07853890600756065DOI Listing
December 2006

Female predominance and transmission distortion in the long-QT syndrome.

N Engl J Med 2006 Dec;355(26):2744-51

INSERM, Institut de Myologie, Université Pierre et Marie Curie, Institut Fédératif de Recherche 14 and Groupe Hospitalier Pitié-Salpêtrière, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMoa042786DOI Listing
December 2006

Reproducibility of computerized measurements of QT interval from multiple leads at rest and during exercise.

Ann Noninvasive Electrocardiol 2006 Oct;11(4):318-26

Helsinki University Hospital, Department of Cardiology, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1542-474X.2006.00124.xDOI Listing
October 2006

Effects of beta-blocker therapy on ventricular repolarization documented by 24-h electrocardiography in patients with type 1 long-QT syndrome.

J Am Coll Cardiol 2006 Aug 25;48(4):747-53. Epub 2006 Jul 25.

Department of Cardiology, Helsinki University Central Hospital, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jacc.2006.04.084DOI Listing
August 2006

[Brugada syndrome, newcomer among inherited cardiac arrhythmias].

Duodecim 2005 ;121(12):1301-8

HYKS:n kardiologian klinikka, Helsinki.

View Article

Download full-text PDF

Source
February 2006

Catecholaminergic polymorphic ventricular tachycardia: recent mechanistic insights.

Cardiovasc Res 2005 Aug;67(3):379-87

Department of Medicine, University of Helsinki, 00290 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cardiores.2005.04.027DOI Listing
August 2005

Temporal repolarization lability differences among genotyped patients with the long QT syndrome.

Am J Cardiol 2004 Nov;94(10):1312-6

Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.amjcard.2004.07.123DOI Listing
November 2004

Genes, exercise and sudden death: molecular basis of familial catecholaminergic polymorphic ventricular tachycardia.

Ann Med 2004 ;36 Suppl 1:81-6

Research Program in Molecular Medicine, Biomedicum Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/17431380410032599DOI Listing
October 2004

Volatile anesthetics and succinylcholine in cardiac ryanodine receptor defects.

Anesth Analg 2004 Aug;99(2):435-7, table of contents

Department of Cardiology, Helsinki University Hospital, PL 340, Haartmaninkatu 4, FIN-00029 HUS, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1213/01.ANE.0000130395.93107.15DOI Listing
August 2004

Loss-of-function mutations of the K(+) channel gene KCNJ2 constitute a rare cause of long QT syndrome.

J Mol Cell Cardiol 2004 Aug;37(2):593-602

Biomedicum Helsinki and Department of Medicine, University of Helsinki, FIN-00290 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yjmcc.2004.05.011DOI Listing
August 2004

Sudden death in familial polymorphic ventricular tachycardia associated with calcium release channel (ryanodine receptor) leak.

Circulation 2004 Jun 14;109(25):3208-14. Epub 2004 Jun 14.

Center for Molecular Cardiology, Department of Physiology and Cellular Biophysics, Columbia University College of Physicians and Surgeons, 630 W. 168th St, P&S 9-401, Box 65, New York, NY 10032, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/01.CIR.0000132472.98675.ECDOI Listing
June 2004

Functional characterization of the common amino acid 897 polymorphism of the cardiac potassium channel KCNH2 (HERG).

Cardiovasc Res 2003 Sep;59(3):603-11

Institute of Biotechnology, Viikinkaari 9, PO Box 56, 00014, University of Helsinki, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0008-6363(03)00458-9DOI Listing
September 2003

Association between HERG K897T polymorphism and QT interval in middle-aged Finnish women.

J Am Coll Cardiol 2002 Aug;40(3):511-4

Division of Cardiology, Department of Medicine, University of Oulu, Oulu, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0735-1097(02)01979-4DOI Listing
August 2002

Differentiation between LQT1 and LQT2 patients and unaffected subjects using 24-hour electrocardiographic recordings.

Am J Cardiol 2002 Mar;89(6):679-85

Department of Medicine, Cardiac Electrophysiology, University of California, San Francisco, San Francisco, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0002-9149(01)02339-6DOI Listing
March 2002

Cardiac findings of reactive arthritis: an observational echocardiographic study.

Rheumatol Int 2002 Mar;21(5):169-72

Department of Medicine, Helsinki University Central Hospital, Huch, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00296-001-0154-yDOI Listing
March 2002

Familial polymorphic ventricular tachycardia--intracellular calcium channel disorder.

Card Electrophysiol Rev 2002 Feb;6(1-2):81-7

Helsinki University Hospital, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1023/a:1017995307543DOI Listing
February 2002