Heikki Kainulainen

Heikki Kainulainen

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Heikki Kainulainen

Publications by authors named "Heikki Kainulainen"

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Fat oxidation at rest and during exercise in male monozygotic twins.

Eur J Appl Physiol 2019 Dec 31;119(11-12):2711-2722. Epub 2019 Oct 31.

Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland.

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http://dx.doi.org/10.1007/s00421-019-04247-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858391PMC
December 2019

Associations of Aerobic Fitness and Maximal Muscular Strength With Metabolites in Young Men.

JAMA Netw Open 2019 Aug 2;2(8):e198265. Epub 2019 Aug 2.

Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland.

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http://dx.doi.org/10.1001/jamanetworkopen.2019.8265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714035PMC
August 2019

Strength Training Improves Metabolic Health Markers in Older Individual Regardless of Training Frequency.

Front Physiol 2019 1;10:32. Epub 2019 Feb 1.

Neuromuscular Research Center, Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland.

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http://dx.doi.org/10.3389/fphys.2019.00032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367240PMC
February 2019

Corrected whole blood biomarkers - the equation of Dill and Costill revisited.

Physiol Rep 2018 06;6(12):e13749

Faculty of Sport and Health Sciences, Biology of Physical Activity, University of Jyväskylä, Jyväskylä, Finland.

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http://dx.doi.org/10.14814/phy2.13749DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016620PMC
June 2018

Acute Metabolic Response, Energy Expenditure, and EMG Activity in Sitting and Standing.

Med Sci Sports Exerc 2017 09;49(9):1927-1934

Neuromuscular Research Center, Biology of Physical Activity, Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, FINLAND.

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http://dx.doi.org/10.1249/MSS.0000000000001305DOI Listing
September 2017

Treatment with soluble activin type IIB-receptor improves bone mass and strength in a mouse model of Duchenne muscular dystrophy.

BMC Musculoskelet Disord 2017 01 19;18(1):20. Epub 2017 Jan 19.

Department of Medical Biochemistry and Genetics, University of Turku, Kiinamyllynkatu 10, FI-20520, Turku, Finland.

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http://dx.doi.org/10.1186/s12891-016-1366-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244551PMC
January 2017

Effects of muscular dystrophy, exercise and blocking activin receptor IIB ligands on the unfolded protein response and oxidative stress.

Free Radic Biol Med 2016 10 20;99:308-322. Epub 2016 Aug 20.

Institute of Biomedicine, Physiology, University of Eastern Finland, Yliopistonranta 1 E, 70210 Kuopio, Finland.

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http://dx.doi.org/10.1016/j.freeradbiomed.2016.08.017DOI Listing
October 2016

Voluntary Running Aids to Maintain High Body Temperature in Rats Bred for High Aerobic Capacity.

Front Physiol 2016 25;7:311. Epub 2016 Jul 25.

Department of Biology of Physical Activity, Neuromuscular Research Center, University of Jyväskylä Jyväskylä, Finland.

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http://dx.doi.org/10.3389/fphys.2016.00311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958631PMC
August 2016

Effects of intrinsic aerobic capacity, aging and voluntary running on skeletal muscle sirtuins and heat shock proteins.

Exp Gerontol 2016 06 31;79:46-54. Epub 2016 Mar 31.

Department of Biology of Physical Activity, University of Jyväskylä, P.O. Box 35, FI-40014 University of Jyväskylä, Jyväskylä, Finland.

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http://dx.doi.org/10.1016/j.exger.2016.03.015DOI Listing
June 2016

iGEMS: an integrated model for identification of alternative exon usage events.

Nucleic Acids Res 2016 Jun 19;44(11):e109. Epub 2016 Apr 19.

Division of Genetics and Molecular Medicine, King's College London, WC2R 2LS, London, UK Research Department, XRGenomics Ltd, 35 Kingsland Road, London E2 8AA, UK

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http://dx.doi.org/10.1093/nar/gkw263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914109PMC
June 2016

DAPIT Over-Expression Modulates Glucose Metabolism and Cell Behaviour in HEK293T Cells.

PLoS One 2015 10;10(7):e0131990. Epub 2015 Jul 10.

Department of Biology of Physical Activity, University of Jyväskylä, Jyväskylä, Finland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0131990PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498893PMC
April 2016

Physical exercise increases adult hippocampal neurogenesis in male rats provided it is aerobic and sustained.

J Physiol 2016 Apr 24;594(7):1855-73. Epub 2016 Feb 24.

Department of Biology of Physical Activity, University of Jyväskylä, Finland.

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http://dx.doi.org/10.1113/JP271552DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818598PMC
April 2016

Physical activity in adulthood: genes and mortality.

Sci Rep 2015 Dec 15;5:18259. Epub 2015 Dec 15.

Department of Health Sciences, University of Jyväskylä, P.O. Box 35, FI-40014 University of Jyväskylä, Jyväskylä, Finland.

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http://dx.doi.org/10.1038/srep18259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678877PMC
December 2015

Muscle inactivity is adversely associated with biomarkers in physically active adults.

Med Sci Sports Exerc 2015 Jun;47(6):1188-96

1Department of Biology of Physical Activity, Neuromuscular Research Center, University of Jyväskylä, FINLAND; 2Department of Sport Sciences, University of Jyväskylä, FINLAND; and 3Department of Health Sciences, Gerontology Research Center, University of Jyväskylä, FINLAND.

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http://dx.doi.org/10.1249/MSS.0000000000000527DOI Listing
June 2015

Physical activity, fitness, glucose homeostasis, and brain morphology in twins.

Med Sci Sports Exerc 2015 Mar;47(3):509-18

1Department of Health Sciences, University of Jyväskylä, Jyväskylä, FINLAND; 2Department of Applied Physics, University of Eastern Finland, Kuopio, FINLAND; 3Department of Psychology, University of Jyväskylä, Jyväskylä, FINLAND; 4Department of Public Health, Hjelt Institute, University of Helsinki, Helsinki, FINLAND; 5Department of Biology of Physical Activity, University of Jyväskylä, Jyväskylä, FINLAND; 6Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki, FINLAND; and 7Institute for Molecular Medicine, University of Helsinki, Helsinki, FINLAND.

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http://dx.doi.org/10.1249/MSS.0000000000000437DOI Listing
March 2015

Myostatin/activin blocking combined with exercise reconditions skeletal muscle expression profile of mdx mice.

Mol Cell Endocrinol 2015 Jan 7;399:131-42. Epub 2014 Oct 7.

Department of Biology of Physical Activity, Neuromuscular Research Center, University of Jyväskylä, Rautpohjankatu 8, P.O. Box 35, Jyväskylä FI-40014, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2014.10.001DOI Listing
January 2015

Label-free profiling of skeletal muscle using high-definition mass spectrometry.

Proteomics 2014 Oct 19;14(20):2339-44. Epub 2014 Aug 19.

Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK.

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http://dx.doi.org/10.1002/pmic.201400118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237019PMC
October 2014

Lipid droplet-associated proteins in high-fat fed mice with the effects of voluntary running and diet change.

Metabolism 2014 Aug 27;63(8):1031-40. Epub 2014 May 27.

Neuromuscular Research Center, Department of Biology of Physical Activity, University of Jyväskylä, Jyväskylä, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2014.05.010DOI Listing
August 2014

Short-term bone biochemical response to a single bout of high-impact exercise.

J Sports Sci Med 2009 1;8(4):553-9. Epub 2009 Dec 1.

Neuromuscular Research Center, Department of Biology of Physical Activity.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3761539PMC
October 2013

Potential role of branched-chain amino acid catabolism in regulating fat oxidation.

Exerc Sport Sci Rev 2013 Oct;41(4):194-200

1Departments of Biology of Physical Activity, and 2Health Sciences, University of Jyväskylä, Jyväskylä, Finland.

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http://dx.doi.org/10.1097/JES.0b013e3182a4e6b6DOI Listing
October 2013

High-fat feeding induces angiogenesis in skeletal muscle and activates angiogenic pathways in capillaries.

Angiogenesis 2013 Apr 23;16(2):297-307. Epub 2012 Oct 23.

Department of Biology of Physical Activity, Neuromuscular Research Center, University of Jyväskylä, P.O. Box 35, 40014, Jyväskylä, Finland.

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http://dx.doi.org/10.1007/s10456-012-9315-8DOI Listing
April 2013

Muscle protein synthesis, mTORC1/MAPK/Hippo signaling, and capillary density are altered by blocking of myostatin and activins.

Am J Physiol Endocrinol Metab 2013 Jan 31;304(1):E41-50. Epub 2012 Oct 31.

Department of Biology of Physical Activity, Neuromuscular Research Center, University of Jyväskylä, Jyväskylä, Finland.

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http://dx.doi.org/10.1152/ajpendo.00389.2012DOI Listing
January 2013

Low-protein vegetarian diet does not have a short-term effect on blood acid-base status but raises oxygen consumption during submaximal cycling.

J Int Soc Sports Nutr 2012 Nov 26;9(1):50. Epub 2012 Nov 26.

Department of Biology of Physical Activity, University of Jyväskylä, P,O, Box 35 (VIV), Jyväskylä, FIN-40014, Finland.

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http://dx.doi.org/10.1186/1550-2783-9-50DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536709PMC
November 2012

Effects of high-fat diet and physical activity on pyruvate dehydrogenase kinase-4 in mouse skeletal muscle.

Nutr Metab (Lond) 2012 Jun 9;9(1):53. Epub 2012 Jun 9.

Neuromuscular Research Center, Department of Biology of Physical Activity, University of Jyväskylä, Jyväskylä, Finland.

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http://dx.doi.org/10.1186/1743-7075-9-53DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407034PMC
June 2012

Altered REDD1, myostatin, and Akt/mTOR/FoxO/MAPK signaling in streptozotocin-induced diabetic muscle atrophy.

Am J Physiol Endocrinol Metab 2012 Feb 8;302(3):E307-15. Epub 2011 Nov 8.

Department of Biology of Physical Activity, Neuromuscular Research Center, University of Jyväskylä, Jyväskylä, Finland.

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http://dx.doi.org/10.1152/ajpendo.00398.2011DOI Listing
February 2012

Extraction of input function from rat [18F]FDG PET images.

Mol Imaging Biol 2011 Dec;13(6):1241-9

Turku PET Centre, University of Turku, Turku, Finland.

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http://dx.doi.org/10.1007/s11307-010-0449-zDOI Listing
December 2011

"Autophagic flux" in normal mouse tissues: focus on endogenous LC3A processing.

Autophagy 2011 Nov 1;7(11):1371-8. Epub 2011 Nov 1.

Department of Radiotherapy-Oncology, Democritus University of Thrace Medical School, University General Hospital of Alexandroupolis, Alexandroupolis, Greece.

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http://dx.doi.org/10.4161/auto.7.11.16664DOI Listing
November 2011

Effects of diet-induced obesity and voluntary wheel running on bone properties in young male C57BL/6J mice.

Calcif Tissue Int 2010 May 13;86(5):411-9. Epub 2010 Mar 13.

Department of Health Sciences, University of Jyväskylä, P.O. Box 35 (LL), 40014 Jyväskylä, Finland.

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http://dx.doi.org/10.1007/s00223-010-9346-3DOI Listing
May 2010

Run more, perform better--old truth revisited.

J Appl Physiol (1985) 2009 May 26;106(5):1477-8. Epub 2009 Feb 26.

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http://dx.doi.org/10.1152/japplphysiol.00200.2009DOI Listing
May 2009

Resistance exercise with whey protein ingestion affects mTOR signaling pathway and myostatin in men.

J Appl Physiol (1985) 2009 May 19;106(5):1720-9. Epub 2009 Mar 19.

Dept. of Biology of Physical Activity, Univ. of Jyväskylä, P.O. Box 35, 40014 Jyväskylä, Finland.

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http://dx.doi.org/10.1152/japplphysiol.00087.2009DOI Listing
May 2009

Effects of fatiguing jumping exercise on mRNA expression of titin-complex proteins and calpains.

J Appl Physiol (1985) 2009 Apr 15;106(4):1419-24. Epub 2009 Jan 15.

LIKES Research Center, Rautpohjankatu 8, FIN-40700 Jyväskylä, Finland.

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http://dx.doi.org/10.1152/japplphysiol.90660.2008DOI Listing
April 2009

Exercise-induced expression of angiogenic growth factors in skeletal muscle and in capillaries of healthy and diabetic mice.

Cardiovasc Diabetol 2008 May 1;7:13. Epub 2008 May 1.

LIKES Research Center for Sport and Health Sciences, Rautpohjankatu 8a, 40700 Jyväskylä, Finland.

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http://dx.doi.org/10.1186/1475-2840-7-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386864PMC
May 2008

Degradative and mechanical properties of a novel resorbable plating system during a 3-year follow-up in vivo and in vitro.

J Mater Sci Mater Med 2008 Mar 15;19(3):1155-63. Epub 2007 Aug 15.

Department of Pharmacological Sciences, Medical School, University of Tampere, Tampere 33014, Finland.

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http://dx.doi.org/10.1007/s10856-007-3082-xDOI Listing
March 2008

Amorphous and crystalline polyetheretherketone: Mechanical properties and tissue reactions during a 3-year follow-up.

J Biomed Mater Res A 2008 Feb;84(2):377-83

Department of Pharmacological Sciences, Medical School, University of Tampere, Finland.

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http://dx.doi.org/10.1002/jbm.a.31310DOI Listing
February 2008

A single bout of exercise with high mechanical loading induces the expression of Cyr61/CCN1 and CTGF/CCN2 in human skeletal muscle.

J Appl Physiol (1985) 2007 Oct 2;103(4):1395-401. Epub 2007 Aug 2.

LIKES Research Center for Sport and Health Sciences, Rautpohjankatu 8a, FIN-40700 Jyväskylä, Finland.

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http://www.physiology.org/doi/10.1152/japplphysiol.00531.200
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http://dx.doi.org/10.1152/japplphysiol.00531.2007DOI Listing
October 2007

Effects of acute exercise, exercise training, and diabetes on the expression of lymphangiogenic growth factors and lymphatic vessels in skeletal muscle.

Am J Physiol Heart Circ Physiol 2007 Oct 31;293(4):H2573-9. Epub 2007 Aug 31.

LIKES Research Center for Sport and Health Sciences, University of Jyväskylä, Rautpohjankatu 8a, FIN-40700 Jyväskylä, Finland.

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http://www.physiology.org/doi/10.1152/ajpheart.00126.2007
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http://dx.doi.org/10.1152/ajpheart.00126.2007DOI Listing
October 2007

Effects of streptozotocin-induced diabetes and physical training on gene expression of titin-based stretch-sensing complexes in mouse striated muscle.

Am J Physiol Endocrinol Metab 2007 Feb 26;292(2):E533-42. Epub 2006 Sep 26.

LIKES Research Center for Sport and Health Sciences, Rautpohjankatu 8, Viveca, FIN-40700 Jyväskylä, Finland.

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http://dx.doi.org/10.1152/ajpendo.00229.2006DOI Listing
February 2007

Gene expression in TGFbeta-induced epithelial cell differentiation in a three-dimensional intestinal epithelial cell differentiation model.

BMC Genomics 2006 Oct 31;7:279. Epub 2006 Oct 31.

Paediatric Research Centre, Tampere University and Tampere University Hospital, Tampere, Finland.

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http://dx.doi.org/10.1186/1471-2164-7-279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635984PMC
October 2006

Murine ortholog of the novel glycosyltransferase, B3GTL: primary structure, characterization of the gene and transcripts, and expression in tissues.

DNA Cell Biol 2006 Aug;25(8):465-74

Paediatric Research Centre, University of Tampere Medical School and Tampere University Hospital, Tampere, Finland.

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http://dx.doi.org/10.1089/dna.2006.25.465DOI Listing
August 2006

Effects of experimental type 1 diabetes and exercise training on angiogenic gene expression and capillarization in skeletal muscle.

FASEB J 2006 Jul;20(9):1570-2

LIKES Research Center for Sport and Health Sciences, Rautpohjankatu 8a, Jyväskylä FIN-40740, Finland.

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http://dx.doi.org/10.1096/fj.05-4780fjeDOI Listing
July 2006

Effects of streptozotocin-induced diabetes and physical training on gene expression of extracellular matrix proteins in mouse skeletal muscle.

Am J Physiol Endocrinol Metab 2006 May 13;290(5):E900-7. Epub 2005 Dec 13.

LIKES Research Center for Sport and Health Sciences, Rautpohjankatu 8, Viveca, FIN-40700 Jyväskylä, Finland.

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http://dx.doi.org/10.1152/ajpendo.00444.2005DOI Listing
May 2006

TGF-beta induces the expression of SAP30L, a novel nuclear protein.

BMC Genomics 2003 Dec 18;4(1):53. Epub 2003 Dec 18.

Paediatric Research Centre, Tampere University Hospital, Tampere, Finland.

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http://dx.doi.org/10.1186/1471-2164-4-53DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC319701PMC
December 2003

A novel human glycosyltransferase: primary structure and characterization of the gene and transcripts.

Biochem Biophys Res Commun 2003 Sep;309(1):166-74

Paediatric Research Centre, University of Tampere Medical School and Tampere University Hospital, Tampere, Finland.

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http://dx.doi.org/10.1016/s0006-291x(03)01540-7DOI Listing
September 2003