Heikki Hyöty

Heikki Hyöty

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Heikki Hyöty

Heikki Hyöty

Publications by authors named "Heikki Hyöty"

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Early childhood infections and the use of antibiotics and antipyretic-analgesics in Finland, Estonia and Russian Karelia.

Acta Paediatr 2019 Nov 23;108(11):2075-2082. Epub 2019 Jun 23.

Pediatric Research Center, Children's Hospital, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1111/apa.14874DOI Listing
November 2019

Temporal variation in indoor transfer of dirt-associated environmental bacteria in agricultural and urban areas.

Environ Int 2019 Nov 7;132:105069. Epub 2019 Aug 7.

Ecosystems and Environment Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Lahti, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.envint.2019.105069DOI Listing
November 2019

Presence of Giardia lamblia in stools of six- to 18-month old asymptomatic Malawians is associated with children's growth failure.

Acta Paediatr 2019 Oct 27;108(10):1833-1840. Epub 2019 May 27.

Center for Child Health Research, Faculty of Medicine and Health Technology and Tampere University Hospital, Tampere University, Tampere, Finland.

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http://dx.doi.org/10.1111/apa.14832DOI Listing
October 2019

Global phylogeography and ancient evolution of the widespread human gut virus crAssphage.

Authors:
Robert A Edwards Alejandro A Vega Holly M Norman Maria Ohaeri Kyle Levi Elizabeth A Dinsdale Ondrej Cinek Ramy K Aziz Katelyn McNair Jeremy J Barr Kyle Bibby Stan J J Brouns Adrian Cazares Patrick A de Jonge Christelle Desnues Samuel L Díaz Muñoz Peter C Fineran Alexander Kurilshikov Rob Lavigne Karla Mazankova David T McCarthy Franklin L Nobrega Alejandro Reyes Muñoz German Tapia Nicole Trefault Alexander V Tyakht Pablo Vinuesa Jeroen Wagemans Alexandra Zhernakova Frank M Aarestrup Gunduz Ahmadov Abeer Alassaf Josefa Anton Abigail Asangba Emma K Billings Vito Adrian Cantu Jane M Carlton Daniel Cazares Gyu-Sung Cho Tess Condeff Pilar Cortés Mike Cranfield Daniel A Cuevas Rodrigo De la Iglesia Przemyslaw Decewicz Michael P Doane Nathaniel J Dominy Lukasz Dziewit Bashir Mukhtar Elwasila A Murat Eren Charles Franz Jingyuan Fu Cristina Garcia-Aljaro Elodie Ghedin Kristen M Gulino John M Haggerty Steven R Head Rene S Hendriksen Colin Hill Heikki Hyöty Elena N Ilina Mitchell T Irwin Thomas C Jeffries Juan Jofre Randall E Junge Scott T Kelley Mohammadali Khan Mirzaei Martin Kowalewski Deepak Kumaresan Steven R Leigh David Lipson Eugenia S Lisitsyna Montserrat Llagostera Julia M Maritz Linsey C Marr Angela McCann Shahar Molshanski-Mor Silvia Monteiro Benjamin Moreira-Grez Megan Morris Lawrence Mugisha Maite Muniesa Horst Neve Nam-Phuong Nguyen Olivia D Nigro Anders S Nilsson Taylor O'Connell Rasha Odeh Andrew Oliver Mariana Piuri Aaron J Prussin Ii Udi Qimron Zhe-Xue Quan Petra Rainetova Adán Ramírez-Rojas Raul Raya Kim Reasor Gillian A O Rice Alessandro Rossi Ricardo Santos John Shimashita Elyse N Stachler Lars C Stene Ronan Strain Rebecca Stumpf Pedro J Torres Alan Twaddle MaryAnn Ugochi Ibekwe Nicolás Villagra Stephen Wandro Bryan White Andy Whiteley Katrine L Whiteson Cisca Wijmenga Maria M Zambrano Henrike Zschach Bas E Dutilh

Nat Microbiol 2019 Oct 8;4(10):1727-1736. Epub 2019 Jul 8.

Theoretical Biology and Bioinformatics, Science4Life, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/s41564-019-0494-6DOI Listing
October 2019

Combination of three virus-derived nanoparticles as a vaccine against enteric pathogens; enterovirus, norovirus and rotavirus.

Vaccine 2019 Oct 1. Epub 2019 Oct 1.

Vaccine Research Center, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2019.09.072DOI Listing
October 2019

Endocrine disruption and commensal bacteria alteration associated with gaseous and soil PAH contamination among daycare children.

Environ Int 2019 Sep 18;130:104894. Epub 2019 Jun 18.

Faculty of Biological and Environmental Sciences, Ecosystems and Environment Research Programme, University of Helsinki, Niemenkatu 73, 15140 Lahti, Finland.

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http://dx.doi.org/10.1016/j.envint.2019.06.004DOI Listing
September 2019

A comparative study of the effect of UV and formalin inactivation on the stability and immunogenicity of a Coxsackievirus B1 vaccine.

Vaccine 2019 Sep 27;37(40):5962-5971. Epub 2019 Aug 27.

Faculty of Medicine and Health Technology, Tampere University, FI-33014 Tampere, Finland; Fimlab Laboratories, Pirkanmaa Hospital District, FI-33520 Tampere, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2019.08.037DOI Listing
September 2019

Formalin treatment increases the stability and immunogenicity of coxsackievirus B1 VLP vaccine.

Antiviral Res 2019 Sep 3;171:104595. Epub 2019 Sep 3.

Faculty of Medicine and Health Technology, Tampere University, FI-33014, Tampere, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.antiviral.2019.104595DOI Listing
September 2019

The relationship between breastfeeding and reported respiratory and gastrointestinal infection rates in young children.

BMC Pediatr 2019 Sep 18;19(1):339. Epub 2019 Sep 18.

Department of Epidemiology, University of Colorado Denver, Colorado School of Public Health, Aurora, CO, USA.

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http://dx.doi.org/10.1186/s12887-019-1693-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749679PMC
September 2019

Rhinoviruses in infancy and risk of immunoglobulin E sensitization.

J Med Virol 2019 Aug 25;91(8):1470-1478. Epub 2019 Mar 25.

Department of Virology, Faculty of Medical Sciences and Biotechnology, Tampere University, Tampere, Finland.

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http://doi.wiley.com/10.1002/jmv.25455
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http://dx.doi.org/10.1002/jmv.25455DOI Listing
August 2019

Circulating metabolites in progression to islet autoimmunity and type 1 diabetes.

Diabetologia 2019 Aug 23. Epub 2019 Aug 23.

Turku Bioscience, University of Turku and Åbo Akademi University, Tykistokatu 6, FI-20520, Turku, Finland.

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http://dx.doi.org/10.1007/s00125-019-04980-0DOI Listing
August 2019

Short-term direct contact with soil and plant materials leads to an immediate increase in diversity of skin microbiota.

Microbiologyopen 2019 03 29;8(3):e00645. Epub 2018 May 29.

Ecosystems and Environment Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Lahti, Finland.

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http://dx.doi.org/10.1002/mbo3.645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436432PMC
March 2019

Development of T cell immunity to norovirus and rotavirus in children under five years of age.

Sci Rep 2019 Mar 1;9(1):3199. Epub 2019 Mar 1.

Vaccine Research Center, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.

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http://dx.doi.org/10.1038/s41598-019-39840-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397277PMC
March 2019

Early childhood CMV infection may decelerate the progression to clinical type 1 diabetes.

Pediatr Diabetes 2019 02 19;20(1):73-77. Epub 2018 Nov 19.

Immunogenetics Laboratory, Institute of Biomedicine, University of Turku, Turku, Finland.

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http://doi.wiley.com/10.1111/pedi.12788
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http://dx.doi.org/10.1111/pedi.12788DOI Listing
February 2019

Enterovirus infection during pregnancy is inversely associated with atopic disease in the offspring.

Clin Exp Allergy 2018 12 16;48(12):1698-1704. Epub 2018 Oct 16.

Department of Virology, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.

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http://dx.doi.org/10.1111/cea.13280DOI Listing
December 2018

Developing a vaccine for type 1 diabetes by targeting coxsackievirus B.

Expert Rev Vaccines 2018 12 29;17(12):1071-1083. Epub 2018 Nov 29.

d Children's Hospital , University of Helsinki and Helsinki University Hospital , Helsinki , Finland.

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http://dx.doi.org/10.1080/14760584.2018.1548281DOI Listing
December 2018

The Environmental Determinants of Diabetes in the Young (TEDDY) Study: 2018 Update.

Curr Diab Rep 2018 10 23;18(12):136. Epub 2018 Oct 23.

Health Informatics Institute, Morsani College of Medicine, University of South Florida, Tampa, FL, USA.

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http://dx.doi.org/10.1007/s11892-018-1113-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415767PMC
October 2018

Strain-Level Analysis of Mother-to-Child Bacterial Transmission during the First Few Months of Life.

Cell Host Microbe 2018 07;24(1):146-154.e4

The Broad Institute of MIT and Harvard, Cambridge, MA 02138, USA; Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Center for Microbiome Informatics and Therapeutics, Massachusetts Institute of Technology, Cambridge, MA 02138, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2018.06.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091882PMC
July 2018

First trimester enterovirus IgM and beta cell autoantibodies in mothers to children affected by type 1 diabetes autoimmunity before 7 years of age.

J Reprod Immunol 2018 06 2;127:1-6. Epub 2018 Mar 2.

Department of Clinical Sciences, Lund University Clinical Research Center, Skåne University Hospital, 205 02 Malmö, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.jri.2018.02.004DOI Listing
June 2018

Nature-derived microbiota exposure as a novel immunomodulatory approach.

Future Microbiol 2018 06 17;13:737-744. Epub 2018 May 17.

Ecosystems and Environment Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Niemenkatu 73, 15140 Lahti, Finland.

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http://dx.doi.org/10.2217/fmb-2017-0286DOI Listing
June 2018

Exocrine pancreas function decreases during the progression of the beta-cell damaging process in young prediabetic children.

Pediatr Diabetes 2018 05 17;19(3):398-402. Epub 2017 Oct 17.

Department of Virology, School of Medicine, University of Tampere, Tampere, Finland.

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http://doi.wiley.com/10.1111/pedi.12592
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http://dx.doi.org/10.1111/pedi.12592DOI Listing
May 2018

New Coxsackievirus 2A and 3C protease antibodies for virus detection and discovery of pathogenic mechanisms.

J Virol Methods 2018 05 6;255:29-37. Epub 2018 Feb 6.

The Center for Infectious Medicine, Department of Medicine HS, Karolinska Institutet, Karolinska University Hospital, Stockholm, 141 86, Sweden; Faculty of Medicine and Life Sciences, University of Tampere, Tampere, 33520, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.jviromet.2018.02.001DOI Listing
May 2018

Quantitative CrAssphage real-time PCR assay derived from data of multiple geographically distant populations.

J Med Virol 2018 04 19;90(4):767-771. Epub 2018 Jan 19.

Centre of Epidemiology and Microbiology, National Institute of Public Health, Prague, Czech Republic.

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http://dx.doi.org/10.1002/jmv.25012DOI Listing
April 2018

Half-lives of PAHs and temporal microbiota changes in commonly used urban landscaping materials.

PeerJ 2018 19;6:e4508. Epub 2018 Mar 19.

Faculty of Biological and Environmental Sciences, Ecosystems and Environment Research Programme, University of Helsinki, Lahti, Finland.

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http://dx.doi.org/10.7717/peerj.4508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863720PMC
March 2018

A Coxsackievirus B vaccine protects against virus-induced diabetes in an experimental mouse model of type 1 diabetes.

Diabetologia 2018 02 18;61(2):476-481. Epub 2017 Nov 18.

The Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, F59, SE-141 86, Stockholm, Sweden.

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http://dx.doi.org/10.1007/s00125-017-4492-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448957PMC
February 2018

Urbanization Reduces Transfer of Diverse Environmental Microbiota Indoors.

Front Microbiol 2018 5;9:84. Epub 2018 Feb 5.

Ecosystems and Environment Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Lahti, Finland.

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http://dx.doi.org/10.3389/fmicb.2018.00084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808279PMC
February 2018

Optimized production and purification of Coxsackievirus B1 vaccine and its preclinical evaluation in a mouse model.

Vaccine 2017 06 1;35(30):3718-3725. Epub 2017 Jun 1.

Faculty of Medicine and Life Sciences, University of Tampere, FI-33520 Tampere, Finland; Fimlab Laboratories, FI-33520 Tampere, Finland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0264410X173070
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http://dx.doi.org/10.1016/j.vaccine.2017.05.057DOI Listing
June 2017

Vipie: web pipeline for parallel characterization of viral populations from multiple NGS samples.

BMC Genomics 2017 05 15;18(1):378. Epub 2017 May 15.

Department of Pediatrics, 2nd Faculty of Medicine, Charles University and University Hospital Motol, V Úvalu 84, 150 06, Praha 5, Czech Republic.

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http://dx.doi.org/10.1186/s12864-017-3721-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430618PMC
May 2017

Human enterovirus and rhinovirus infections are associated with otitis media in a prospective birth cohort study.

J Clin Virol 2016 12 20;85:1-6. Epub 2016 Oct 20.

School of Medicine, University of Tampere, Lääkärinkatu 1, FIN-33520, Tampere, Finland; Fimlab Laboratories, Pirkanmaa Hospital District, Tampere, Finland.

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http://dx.doi.org/10.1016/j.jcv.2016.10.010DOI Listing
December 2016

Moraxella catarrhalis Might Be More Common than Expected in Acute Otitis Media in Young Finnish Children.

J Clin Microbiol 2016 09 13;54(9):2373-9. Epub 2016 Jul 13.

Department of Pediatrics, 2nd Faculty of Medicine, Charles University in Prague, and University Hospital Motol, Prague, Czech Republic.

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http://jcm.asm.org/lookup/doi/10.1128/JCM.01146-16
Publisher Site
http://dx.doi.org/10.1128/JCM.01146-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005485PMC
September 2016

Viruses in type 1 diabetes.

Authors:
Heikki Hyöty

Pediatr Diabetes 2016 07;17 Suppl 22:56-64

Department of Virology, School of Medicine, University of Tampere, Tampere, Finland.

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http://dx.doi.org/10.1111/pedi.12370DOI Listing
July 2016

Antibiotic resistance in pathogens causing acute otitis media in Finnish children.

Int J Pediatr Otorhinolaryngol 2016 Jun 11;85:91-4. Epub 2016 Apr 11.

Department of Otorhinolaryngology and Head and Neck Surgery, Tampere University Hospital and School of Medicine, University of Tampere, 33520 Tampere, Finland.

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http://dx.doi.org/10.1016/j.ijporl.2016.03.037DOI Listing
June 2016

Development and maturation of norovirus antibodies in childhood.

Microbes Infect 2016 Apr 25;18(4):263-9. Epub 2015 Dec 25.

Vaccine Research Center, University of Tampere Medical School, Tampere, Finland.

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http://dx.doi.org/10.1016/j.micinf.2015.12.004DOI Listing
April 2016

Serum 25-Hydroxyvitamin D Concentrations in Children Progressing to Autoimmunity and Clinical Type 1 Diabetes.

J Clin Endocrinol Metab 2016 Feb 22;101(2):723-9. Epub 2015 Dec 22.

Medicity (M.M., M.Ko., V.S.), Department of Pediatrics (M.M., J.M., M.Ko., J.T.), Immunogenetics Laboratory (J.I.), University of Turku and Turku University Hospital, and Research Center of Applied and Preventive Cardiovascular Medicine (O.S.), and Department of Physiology (J.T.), Institute of Biomedicine, University of Turku, FI-20520 Turku, Finland; Department of Pediatrics (R.V.), Research Unit for Pediatrics, Dermatology, Clinical Genetics, Obstetrics and Gynecology, Medical Research Center Oulu, University of Oulu, FI 90014 Oulu, Finland; Department of Children and Adolescents (R.V.), Oulu University Hospital, FI 90029 Oulu, Finland; Department of Virology (H.H.), School of Medicine, University of Tampere, and Department of Pediatrics (M.Kn.), Tampere University Hospital, FI-33520 Tampere, Finland; Fimlab Laboratories (H.H.), Pirkanmaa Hospital District, FI-33014 Tampere, Finland; Children's Hospital (M.Kn.), University of Helsinki and Helsinki University Hospital, Research Programs Unit (M.Kn.), Diabetes and Obesity, University of Helsinki, and Folkhälsan Research Center (M.Kn.), FI-00290 Helsinki, Finland.

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http://dx.doi.org/10.1210/jc.2015-3504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880127PMC
February 2016

Multiple consecutive norovirus infections in the first 2 years of life.

Eur J Pediatr 2015 Dec 9;174(12):1679-83. Epub 2015 Jul 9.

Vaccine Research Center, University of Tampere Medical School, Biokatu 10, FI-33520, Tampere, Finland.

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http://dx.doi.org/10.1007/s00431-015-2591-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662724PMC
December 2015

Investigation of CTLA-4-318C/T gene polymorphism in cases with type 1 diabetes of Azerbaijan, Northwest Iran.

Immunol Lett 2015 Aug 5;166(2):134-9. Epub 2015 Jun 5.

Department of Immunology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.

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http://dx.doi.org/10.1016/j.imlet.2015.05.021DOI Listing
August 2015

Application of bioinformatics in probe design enables detection of enteroviruses on different taxonomic levels by advanced in situ hybridization technology.

J Clin Virol 2015 Aug 23;69:165-71. Epub 2015 Jun 23.

Department of Virology, Medical School, University of Tampere, Tampere, Finland; Fimlab Laboratories, Pirkanmaa Hospital District, Tampere, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.jcv.2015.06.085DOI Listing
August 2015

High-throughput multiplex quantitative polymerase chain reaction method for Giardia lamblia and Cryptosporidium species detection in stool samples.

Am J Trop Med Hyg 2015 Jun 27;92(6):1222-6. Epub 2015 Apr 27.

Department of Virology, School of Medicine, University of Tampere, Finland; Department for International Health, School of Medicine, University of Tampere, Finland; School of Public Health and Family Medicine, College of Medicine, University of Malawi, Blantyre, Malawi; Department of Pediatrics, Tampere University Hospital, Tampere, Finland; Fimlab Laboratories, Pirkanmaa Hospital District, Tampere, Finland

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http://dx.doi.org/10.4269/ajtmh.15-0054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458829PMC
June 2015

Gut virome sequencing in children with early islet autoimmunity.

Diabetes Care 2015 May 12;38(5):930-3. Epub 2015 Feb 12.

Department of Pediatrics, University Hospital Motol, and 2nd Faculty of Medicine, Charles University in Prague, Prague, Czech Republic

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http://dx.doi.org/10.2337/dc14-2490DOI Listing
May 2015

Role of viruses and other microbes in the pathogenesis of type 1 diabetes.

Int Rev Immunol 2014 Jul-Aug;33(4):284-95. Epub 2014 Mar 10.

School of Medicine, University of Tampere , Tampere , Finland.

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http://www.tandfonline.com/doi/full/10.3109/08830185.2014.88
Publisher Site
http://dx.doi.org/10.3109/08830185.2014.889130DOI Listing
April 2015

Age-associated DNA methylation changes in immune genes, histone modifiers and chromatin remodeling factors within 5 years after birth in human blood leukocytes.

Clin Epigenetics 2015 26;7:34. Epub 2015 Mar 26.

Department of Biosciences and Nutrition, Center for Innovative Medicine, Karolinska Institutet, Stockholm, Sweden ; Folkhälsan Institute of Genetics, Helsinki, and Research Programs Unit, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1186/s13148-015-0064-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396570PMC
April 2015

Human parechovirus as a minor cause of acute otitis media in children.

J Clin Virol 2015 Jan 8;62:106-9. Epub 2014 Nov 8.

Department of Virology, School of Medicine, University of Tampere, 33520 Tampere, Finland; Fimlab Laboratories, Pirkanmaa Hospital District, 33520 Tampere, Finland.

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http://dx.doi.org/10.1016/j.jcv.2014.11.002DOI Listing
January 2015

An increase in serum 25-hydroxyvitamin D concentrations preceded a plateau in type 1 diabetes incidence in Finnish children.

J Clin Endocrinol Metab 2014 Nov 25;99(11):E2353-6. Epub 2014 Jul 25.

Department of Pediatrics (M.M., V.S., J.M., O.S., J.T., R.H.), University of Turku, 20520 Turku, Finland and Turku University Hospital, 20520 Turku, Finland; Immunogenetics Laboratory (J.I.), University of Turku, 20520 Turku, Finland; Department of Clinical Microbiology (J.I.), University of Eastern Finland, 70211 Kuopio, Finland; Department of Pediatrics (R.V.), University of Oulu, 90014 Oulu, Finland and Oulu University Hospital, 90029 Oulu, Finland; Department of Virology (H.H.), University of Tampere, 33520 Tampere, Finland; Fimlab Laboratories (H.H.), Pirkanmaa Hospital District, 33520 Tampere, Finland; Children's Hospital (M.K.), University of Helsinki and Helsinki University Central Hospital 00029 Helsinki, Finland; Diabetes and Obesity Research Program (M.K.), University of Helsinki, 00014 Helsinki, Finland; Folkhälsan Research Center (M.K.), 00290 Helsinki, Finland; Department of Pediatrics (M.K.), Tampere University Hospital, 33521 Tampere, Finland; and Department of Physiology (J.T.), University of Turku, 20520 Turku, Finland.

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http://dx.doi.org/10.1210/jc.2014-1455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596932PMC
November 2014

Enterovirus RNA in longitudinal blood samples and risk of islet autoimmunity in children with a high genetic risk of type 1 diabetes: the MIDIA study.

Diabetologia 2014 Oct 23;57(10):2193-200. Epub 2014 Jul 23.

Department of Paediatrics, 2nd Faculty of Medicine, Charles University in Prague and University Hospital Motol, V Uvalu 84, 15006, Prague 5, Czech Republic,

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http://dx.doi.org/10.1007/s00125-014-3327-4DOI Listing
October 2014

Aberrant gut microbiota composition at the onset of type 1 diabetes in young children.

Diabetologia 2014 Aug 15;57(8):1569-77. Epub 2014 Jun 15.

Department of Medical Microbiology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, HPC EB80, 9713 GZ, Groningen, The Netherlands.

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http://dx.doi.org/10.1007/s00125-014-3274-0DOI Listing
August 2014

Microbial exposure in infancy and subsequent appearance of type 1 diabetes mellitus-associated autoantibodies: a cohort study.

JAMA Pediatr 2014 Aug;168(8):755-63

Center for Child Health Research, University of Tampere and Tampere University Hospital, Tampere, Finland7Children's Hospital, University of Helsinki, and University Central Hospital, Helsinki, Finland8University of Helsinki, Diabetes and Obesity Research.

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http://dx.doi.org/10.1001/jamapediatrics.2014.296DOI Listing
August 2014

Developing a vaccine for Type 1 diabetes through targeting enteroviral infections.

Expert Rev Vaccines 2014 Aug 26;13(8):989-99. Epub 2014 Jun 26.

School of Medicine, University of Tampere, Tampere, Finland.

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http://dx.doi.org/10.1586/14760584.2014.933078DOI Listing
August 2014

Innate immune activity is detected prior to seroconversion in children with HLA-conferred type 1 diabetes susceptibility.

Diabetes 2014 Jul 18;63(7):2402-14. Epub 2014 Feb 18.

Turku Centre for Biotechnology, University of Turku and Åbo Akademi University, Turku, FinlandThe Finnish Centre of Excellence in Molecular Systems Immunology and Physiology Research, Helsinki, Finland

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http://dx.doi.org/10.2337/db13-1775DOI Listing
July 2014

Presence of human enteric viruses in the stools of healthy Malawian 6-month-old infants.

J Pediatr Gastroenterol Nutr 2014 Apr;58(4):502-4

*Functional Foods Forum, University of Turku, Turku, Finland †Department of Biotechnology, Institute of Agrochemistry and Food Technology-Spanish National Research Council (IATA-CSIC), Valencia, Spain ‡School of Medicine, University of Tampere, Tampere, Finland §Department of Community Health, College of Medicine, University, Blantyre, Malawi ||Department of International Health, School of Medicine, University of Tampere, Tampere, Finland.

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http://dx.doi.org/10.1097/MPG.0000000000000215DOI Listing
April 2014

Pancreatic biopsy by minimal tail resection in live adult patients at the onset of type 1 diabetes: experiences from the DiViD study.

Diabetologia 2014 Apr 16;57(4):841-3. Epub 2014 Jan 16.

Paediatric Department, Oslo University Hospital HF, P. O. Box, 4950, Nydalen, 0424, Oslo, Norway,

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http://dx.doi.org/10.1007/s00125-013-3155-yDOI Listing
April 2014

Food diversity in infancy and the risk of childhood asthma and allergies.

J Allergy Clin Immunol 2014 Apr 25;133(4):1084-91. Epub 2014 Jan 25.

School of Health Sciences, University of Tampere, Tampere, Finland; Nutrition Unit, Department of Lifestyle and Participation, National Institute for Health and Welfare, Helsinki, Finland; Department of Pediatrics, Tampere University Hospital, Tampere, Finland; Science Center of Pirkanmaa Hospital District, Tampere, Finland.

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http://dx.doi.org/10.1016/j.jaci.2013.12.1069DOI Listing
April 2014

Coxsackievirus B3 VLPs purified by ion exchange chromatography elicit strong immune responses in mice.

Antiviral Res 2014 Apr 28;104:93-101. Epub 2014 Jan 28.

Vactech Ltd, Biokatu 8, FI-33520 Tampere, Finland; The Center for Infectious Medicine, Department of Medicine HS, Karolinska Institutet, Karolinska University Hospital Huddinge F59, SE-141 86 Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.antiviral.2014.01.013DOI Listing
April 2014