Heike Fiegler

Heike Fiegler

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Heike Fiegler

Heike Fiegler

Publications by authors named "Heike Fiegler"

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Replication-timing-correlated spatial chromatin arrangements in cancer and in primate interphase nuclei.

J Cell Sci 2008 Jun 13;121(11):1876-86. Epub 2008 May 13.

Department of Biology II, Human Genetics, Ludwig-Maximilians University Munich, Planegg-Martinsreid, Germany.

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http://dx.doi.org/10.1242/jcs.026989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687722PMC
June 2008

Breaking the waves: improved detection of copy number variation from microarray-based comparative genomic hybridization.

Genome Biol 2007 ;8(10):R228

Computational Biology Group, Department of Applied Mathematics and Theoretical Physics, University of Cambridge, Centre for Mathematical Sciences, Wilberforce Road, Cambridge CB3 0WA, UK.

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http://dx.doi.org/10.1186/gb-2007-8-10-r228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246302PMC
May 2008

Germline rates of de novo meiotic deletions and duplications causing several genomic disorders.

Nat Genet 2008 Jan 2;40(1):90-5. Epub 2007 Dec 2.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, CB10 1SA, UK.

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http://dx.doi.org/10.1038/ng.2007.40DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669897PMC
January 2008

Diet and the evolution of human amylase gene copy number variation.

Nat Genet 2007 Oct 9;39(10):1256-60. Epub 2007 Sep 9.

School of Human Evolution and Social Change, Arizona State University, Tempe, Arizona 85287, USA.

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http://dx.doi.org/10.1038/ng2123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377015PMC
October 2007

Radial chromatin positioning is shaped by local gene density, not by gene expression.

Chromosoma 2007 Jun 27;116(3):285-306. Epub 2007 Feb 27.

Department of Biology II, Anthropology and Human Genetics, Ludwig Maximilians University, Munich, Germany.

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http://dx.doi.org/10.1007/s00412-007-0098-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688818PMC
June 2007

Construction and use of spotted large-insert clone DNA microarrays for the detection of genomic copy number changes.

Nat Protoc 2007 ;2(3):577-87

The Wellcome Trust Sanger Institute, The Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

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http://www.nature.com/articles/nprot.2007.53
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http://dx.doi.org/10.1038/nprot.2007.53DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688820PMC
June 2007

Spreading of mammalian DNA-damage response factors studied by ChIP-chip at damaged telomeres.

EMBO J 2007 Jun 10;26(11):2707-18. Epub 2007 May 10.

The Wellcome Trust and Cancer Research UK Gurdon Institute, Department of Zoology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1038/sj.emboj.7601719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1888678PMC
June 2007

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.

Authors:
Ewan Birney John A Stamatoyannopoulos Anindya Dutta Roderic Guigó Thomas R Gingeras Elliott H Margulies Zhiping Weng Michael Snyder Emmanouil T Dermitzakis Robert E Thurman Michael S Kuehn Christopher M Taylor Shane Neph Christoph M Koch Saurabh Asthana Ankit Malhotra Ivan Adzhubei Jason A Greenbaum Robert M Andrews Paul Flicek Patrick J Boyle Hua Cao Nigel P Carter Gayle K Clelland Sean Davis Nathan Day Pawandeep Dhami Shane C Dillon Michael O Dorschner Heike Fiegler Paul G Giresi Jeff Goldy Michael Hawrylycz Andrew Haydock Richard Humbert Keith D James Brett E Johnson Ericka M Johnson Tristan T Frum Elizabeth R Rosenzweig Neerja Karnani Kirsten Lee Gregory C Lefebvre Patrick A Navas Fidencio Neri Stephen C J Parker Peter J Sabo Richard Sandstrom Anthony Shafer David Vetrie Molly Weaver Sarah Wilcox Man Yu Francis S Collins Job Dekker Jason D Lieb Thomas D Tullius Gregory E Crawford Shamil Sunyaev William S Noble Ian Dunham France Denoeud Alexandre Reymond Philipp Kapranov Joel Rozowsky Deyou Zheng Robert Castelo Adam Frankish Jennifer Harrow Srinka Ghosh Albin Sandelin Ivo L Hofacker Robert Baertsch Damian Keefe Sujit Dike Jill Cheng Heather A Hirsch Edward A Sekinger Julien Lagarde Josep F Abril Atif Shahab Christoph Flamm Claudia Fried Jörg Hackermüller Jana Hertel Manja Lindemeyer Kristin Missal Andrea Tanzer Stefan Washietl Jan Korbel Olof Emanuelsson Jakob S Pedersen Nancy Holroyd Ruth Taylor David Swarbreck Nicholas Matthews Mark C Dickson Daryl J Thomas Matthew T Weirauch James Gilbert Jorg Drenkow Ian Bell XiaoDong Zhao K G Srinivasan Wing-Kin Sung Hong Sain Ooi Kuo Ping Chiu Sylvain Foissac Tyler Alioto Michael Brent Lior Pachter Michael L Tress Alfonso Valencia Siew Woh Choo Chiou Yu Choo Catherine Ucla Caroline Manzano Carine Wyss Evelyn Cheung Taane G Clark James B Brown Madhavan Ganesh Sandeep Patel Hari Tammana Jacqueline Chrast Charlotte N Henrichsen Chikatoshi Kai Jun Kawai Ugrappa Nagalakshmi Jiaqian Wu Zheng Lian Jin Lian Peter Newburger Xueqing Zhang Peter Bickel John S Mattick Piero Carninci Yoshihide Hayashizaki Sherman Weissman Tim Hubbard Richard M Myers Jane Rogers Peter F Stadler Todd M Lowe Chia-Lin Wei Yijun Ruan Kevin Struhl Mark Gerstein Stylianos E Antonarakis Yutao Fu Eric D Green Ulaş Karaöz Adam Siepel James Taylor Laura A Liefer Kris A Wetterstrand Peter J Good Elise A Feingold Mark S Guyer Gregory M Cooper George Asimenos Colin N Dewey Minmei Hou Sergey Nikolaev Juan I Montoya-Burgos Ari Löytynoja Simon Whelan Fabio Pardi Tim Massingham Haiyan Huang Nancy R Zhang Ian Holmes James C Mullikin Abel Ureta-Vidal Benedict Paten Michael Seringhaus Deanna Church Kate Rosenbloom W James Kent Eric A Stone Serafim Batzoglou Nick Goldman Ross C Hardison David Haussler Webb Miller Arend Sidow Nathan D Trinklein Zhengdong D Zhang Leah Barrera Rhona Stuart David C King Adam Ameur Stefan Enroth Mark C Bieda Jonghwan Kim Akshay A Bhinge Nan Jiang Jun Liu Fei Yao Vinsensius B Vega Charlie W H Lee Patrick Ng Atif Shahab Annie Yang Zarmik Moqtaderi Zhou Zhu Xiaoqin Xu Sharon Squazzo Matthew J Oberley David Inman Michael A Singer Todd A Richmond Kyle J Munn Alvaro Rada-Iglesias Ola Wallerman Jan Komorowski Joanna C Fowler Phillippe Couttet Alexander W Bruce Oliver M Dovey Peter D Ellis Cordelia F Langford David A Nix Ghia Euskirchen Stephen Hartman Alexander E Urban Peter Kraus Sara Van Calcar Nate Heintzman Tae Hoon Kim Kun Wang Chunxu Qu Gary Hon Rosa Luna Christopher K Glass M Geoff Rosenfeld Shelley Force Aldred Sara J Cooper Anason Halees Jane M Lin Hennady P Shulha Xiaoling Zhang Mousheng Xu Jaafar N S Haidar Yong Yu Yijun Ruan Vishwanath R Iyer Roland D Green Claes Wadelius Peggy J Farnham Bing Ren Rachel A Harte Angie S Hinrichs Heather Trumbower Hiram Clawson Jennifer Hillman-Jackson Ann S Zweig Kayla Smith Archana Thakkapallayil Galt Barber Robert M Kuhn Donna Karolchik Lluis Armengol Christine P Bird Paul I W de Bakker Andrew D Kern Nuria Lopez-Bigas Joel D Martin Barbara E Stranger Abigail Woodroffe Eugene Davydov Antigone Dimas Eduardo Eyras Ingileif B Hallgrímsdóttir Julian Huppert Michael C Zody Gonçalo R Abecasis Xavier Estivill Gerard G Bouffard Xiaobin Guan Nancy F Hansen Jacquelyn R Idol Valerie V B Maduro Baishali Maskeri Jennifer C McDowell Morgan Park Pamela J Thomas Alice C Young Robert W Blakesley Donna M Muzny Erica Sodergren David A Wheeler Kim C Worley Huaiyang Jiang George M Weinstock Richard A Gibbs Tina Graves Robert Fulton Elaine R Mardis Richard K Wilson Michele Clamp James Cuff Sante Gnerre David B Jaffe Jean L Chang Kerstin Lindblad-Toh Eric S Lander Maxim Koriabine Mikhail Nefedov Kazutoyo Osoegawa Yuko Yoshinaga Baoli Zhu Pieter J de Jong
June 2007

High resolution array-CGH analysis of single cells.

Nucleic Acids Res 2007 18;35(3):e15. Epub 2006 Dec 18.

The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

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http://dx.doi.org/10.1093/nar/gkl1030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1807964PMC
March 2007

Micro-array analyses decipher exceptional complex familial chromosomal rearrangement.

Hum Genet 2006 Mar 3;119(1-2):145-53. Epub 2006 Jan 3.

Institut für Humangenetik, Technische Universität München, Trogerstr. 32, 81675 München, Germany.

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http://link.springer.com/10.1007/s00439-005-0103-z
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http://dx.doi.org/10.1007/s00439-005-0103-zDOI Listing
March 2006

Deletion at chromosome band 20p12.1 in colorectal cancer revealed by high resolution array comparative genomic hybridization.

Genes Chromosomes Cancer 2005 Dec;44(4):384-91

The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

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http://doi.wiley.com/10.1002/gcc.20252
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http://dx.doi.org/10.1002/gcc.20252DOI Listing
December 2005

Genomic and protein expression profiling identifies CDK6 as novel independent prognostic marker in medulloblastoma.

J Clin Oncol 2005 Dec;23(34):8853-62

Division of Molecular Genetics (B060), German Cancer Research Center, Im Neuenheimer Feld 580, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1200/JCO.2005.02.8589DOI Listing
December 2005

Refining molecular analysis in the pathways of colorectal carcinogenesis.

Clin Gastroenterol Hepatol 2005 Nov;3(11):1115-23

Molecular and Population Genetics Laboratory, London Research Institute, Cancer Research UK, 44 Lincoln's Inn Fields, London WC2A 3PX, UK.

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http://dx.doi.org/10.1016/s1542-3565(05)00618-xDOI Listing
November 2005

Investigating chromosome organization with genomic microarrays.

Chromosome Res 2005 ;13(3):249-57

Department of Medical and Molecular Genetics, GKT School of Medicine, King's College London, London, SE1 9RT, UK.

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http://dx.doi.org/10.1007/s10577-005-1504-5DOI Listing
August 2005

Genomic array technology.

Methods Cell Biol 2004 ;75:769-85

The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, United Kingdom.

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http://dx.doi.org/10.1016/s0091-679x(04)75033-5DOI Listing
March 2005

Array-CGH analysis of microsatellite-stable, near-diploid bowel cancers and comparison with other types of colorectal carcinoma.

Oncogene 2005 Jan;24(1):118-29

Molecular and Population Genetics Laboratory, Cancer Research UK, 44 Lincoln's Inn Fields, London WC2A 3PX, UK.

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http://dx.doi.org/10.1038/sj.onc.1208194DOI Listing
January 2005

Analysis of ovarian cancer cell lines using array-based comparative genomic hybridization.

J Pathol 2005 Jan;205(1):29-40

Molecular and Population Genetics Laboratory, Cancer Research UK, London, UK.

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http://dx.doi.org/10.1002/path.1681DOI Listing
January 2005

Replication timing of human chromosome 6.

Cell Cycle 2005 Jan 5;4(1):172-6. Epub 2005 Jan 5.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

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https://www.tandfonline.com/doi/full/10.4161/cc.4.1.1350
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http://dx.doi.org/10.4161/cc.4.1.1350DOI Listing
January 2005

Array comparative genomic hybridization analysis of colorectal cancer cell lines and primary carcinomas.

Cancer Res 2004 Jul;64(14):4817-25

The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

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http://dx.doi.org/10.1158/0008-5472.CAN-04-0328DOI Listing
July 2004

High-resolution analysis of genomic copy number alterations in bladder cancer by microarray-based comparative genomic hybridization.

Oncogene 2004 Mar;23(12):2250-63

Cancer Research UK Clinical Centre, St James's University Hospital, Beckett St, Leeds LS9 7TF, UK.

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http://dx.doi.org/10.1038/sj.onc.1207260DOI Listing
March 2004

Replication timing of the human genome.

Hum Mol Genet 2004 Jan 25;13(2):191-202. Epub 2003 Nov 25.

The Welcome Trust Sanger Institute, Welcome Genome Campus, Cambridge, UK.

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http://dx.doi.org/10.1093/hmg/ddh016DOI Listing
January 2004

A DNA damage checkpoint response in telomere-initiated senescence.

Nature 2003 Nov 5;426(6963):194-8. Epub 2003 Nov 5.

[1] The Wellcome Trust/Cancer Research UK Institute of Cancer and Developmental Biology, University of Cambridge, Cambridge CB2 1QR, UK [2] Present address: IFOM-FIRC Institute of Molecular Oncology, via Adamello 16, 20139 Milan, Italy.

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http://dx.doi.org/10.1038/nature02118DOI Listing
November 2003

DNA microarrays for comparative genomic hybridization based on DOP-PCR amplification of BAC and PAC clones.

Genes Chromosomes Cancer 2003 Apr;36(4):361-74

Wellcome Trust Sanger Institute/Cancer Research UK Genomic Microarray Group, Hinxton, Cambridge, CB10 1SA, United Kingdom.

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http://doi.wiley.com/10.1002/gcc.10155
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http://dx.doi.org/10.1002/gcc.10155DOI Listing
April 2003

Transient expression of PU.1 commits multipotent progenitors to a myeloid fate whereas continued expression favors macrophage over granulocyte differentiation.

Exp Hematol 2003 Jan;31(1):39-47

Laboratory of Molecular Medicine, Interdisciplinary Centre for Clinical Research, University of Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.1016/s0301-472x(02)01017-2DOI Listing
January 2003

Determination of donor-type chimerism using a semi-quantitative PCR-based method in a canine model for bone marrow transplantation.

Vet Immunol Immunopathol 2002 Jan;84(1-2):61-70

GSF-Forschungszentrum für Umwelt und Gesundheit, Institut für Klinische Molekularbiologie und Tumorgenetik, 81377, München, Germany.

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http://dx.doi.org/10.1016/s0165-2427(01)00390-7DOI Listing
January 2002