Publications by authors named "Heike Allgayer"

85Publications

MicroRNAs in the Tumor Microenvironment.

Adv Exp Med Biol 2020 ;1277:1-31

Department of Experimental Surgery - Cancer Metastasis, Medical Faculty Mannheim, Ruprecht Karls University of Heidelberg, Mannheim, Germany.

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http://dx.doi.org/10.1007/978-3-030-50224-9_1DOI Listing
January 2020

NF1-RAC1 axis regulates migration of the melanocytic lineage.

Transl Oncol 2020 Dec 4;13(12):100858. Epub 2020 Sep 4.

Skin Cancer Unit, German Cancer Research Center (DKFZ), Heidelberg, Germany; Department of Dermatology, Venereology and Allergology, University Medical Center Mannheim, Ruprecht-Karls University of Heidelberg, Mannheim, Germany.

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http://dx.doi.org/10.1016/j.tranon.2020.100858DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484592PMC
December 2020

Filtering maxRatio results with machine learning models increases quantitative PCR accuracy over the fit point method.

J Microbiol Methods 2020 02 4;169:105803. Epub 2019 Dec 4.

Department of Experimental Surgery - Cancer Metastasis, Medical Faculty Mannheim, Centre for Biomedicine and Medical Technology Mannheim (CBTM), Ludolf-Krehl-Str. 6, 68135 Mannheim, Ruprecht-Karls University of Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.mimet.2019.105803DOI Listing
February 2020

Defining the "Metastasome": Perspectives from the genome and molecular landscape in colorectal cancer for metastasis evolution and clinical consequences.

Semin Cancer Biol 2020 02 27;60:1-13. Epub 2019 Jul 27.

Department of Experimental Surgery - Cancer Metastasis, Medical Faculty Mannheim, Theodor Kutzer Ufer 1-3, 68135, Mannheim, Ruprecht Karls University of Heidelberg, Germany; Centre for Biomedicine and Medical Technology Mannheim (CBTM), Medical Faculty Mannheim, Ludolf-Krehl-Str. 6, 68135, Mannheim, Ruprecht Karls University of Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.semcancer.2019.07.018DOI Listing
February 2020

Editorial Comment: Deciphering the "Metastasome" Leads to Novel Hypotheses on Understanding the Evolution of Metastasis and Implicates Consequences for Metastasis Therapy and Prevention.

Authors:
Heike Allgayer

Cancer Microenviron 2019 Apr;12(1):1-2

Department of Experimental Surgery-Cancer Metastasis, Medical Faculty Mannheim, Ruprecht Karls University, Ludolf Krehl Str.13-17, 68167, Mannheim, Germany.

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http://dx.doi.org/10.1007/s12307-019-00221-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529474PMC
April 2019

Mingle: A Command Line Utility for Merging Multi-fasta Files.

J Comput Biol 2019 04 14;26(4):396-404. Epub 2019 Feb 14.

Department of Experimental Surgery-Cancer Metastasis, Medical Faculty Mannheim, Centre for Biomedicine and Medical Technology Mannheim (CBTM), Ruprecht-Karls University of Heidelberg, Mannheim, Germany.

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http://dx.doi.org/10.1089/cmb.2018.0243DOI Listing
April 2019

Standard Approach to Gastrointestinal Stromal Tumors - Differences between China and Europe.

Visc Med 2018 Oct 19;34(5):353-358. Epub 2018 Oct 19.

Department of Gastrointestinal Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

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https://www.karger.com/Article/FullText/494347
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http://dx.doi.org/10.1159/000494347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257205PMC
October 2018

Prevention of carcinogenesis and metastasis by Artemisinin-type drugs.

Cancer Lett 2018 08 8;429:11-18. Epub 2018 May 8.

Department of Experimental Surgery - Cancer Metastasis, Medical Faculty Mannheim, Center for Biomedicine and Medical Technology Mannheim (CBTM), Ludolf-Krehl-Str. 6, 68135 Mannheim, Ruprecht-Karls University of Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2018.05.008DOI Listing
August 2018

P53-induced miR-30e-5p inhibits colorectal cancer invasion and metastasis by targeting ITGA6 and ITGB1.

Int J Cancer 2017 11 24;141(9):1879-1890. Epub 2017 Jul 24.

Department of Experimental Surgery-Cancer Metastasis, Medical Faculty Mannheim, University of Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.30854DOI Listing
November 2017

MicroRNAs-from metastasis prediction to metastasis prevention?

Mol Cell Oncol 2016 Mar 10;3(2):e1074336. Epub 2015 Dec 10.

Department of Experimental Surgery, Medical Faculty Mannheim, Theodor Kutzer Ufer 1-3, 68135 Mannheim, Ruprecht Karl University of Heidelberg, Germany; Centre for Biomedicine and Medical Technology Mannheim (CBTM), Medical Faculty Mannheim, Ludolf-Krehl-Str. 6, 68135 Mannheim, Ruprecht Karl University of Heidelberg, Germany.

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http://dx.doi.org/10.1080/23723556.2015.1074336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905395PMC
March 2016

Two wavelength-shifting molecular beacons for simultaneous and selective imaging of vesicular miRNA-21 and miRNA-31 in living cancer cells.

Org Biomol Chem 2016 Jun 26;14(22):5001-6. Epub 2016 Apr 26.

Institute of Organic Chemistry, Karlsruhe Institute of Technology (KIT), Fritz-Haber-Weg 6, 76131 Karlsruhe, Germany.

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http://dx.doi.org/10.1039/c6ob00691dDOI Listing
June 2016

miRs-134 and -370 function as tumor suppressors in colorectal cancer by independently suppressing EGFR and PI3K signalling.

Sci Rep 2016 Apr 20;6:24720. Epub 2016 Apr 20.

Department of Experimental Surgery, Medical Faculty Mannheim, University of Heidelberg, Germany.

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http://dx.doi.org/10.1038/srep24720DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837379PMC
April 2016

MicroRNAs as novel targets and tools in cancer therapy.

Cancer Lett 2017 02 1;387:84-94. Epub 2016 Apr 1.

Department of Experimental Surgery, Medical Faculty Mannheim, and Center for Biomedicine and Medical Technology Mannheim (CBTM), Ruprecht-Karls University of Heidelberg, Ludolf-Krehl-Str. 6, 68135 Mannheim, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2016.03.043DOI Listing
February 2017

MicroRNA Regulation of Epithelial to Mesenchymal Transition.

J Clin Med 2016 Jan 14;5(1). Epub 2016 Jan 14.

Department of Experimental Surgery, Center for Biomedicine and Medical Technology Mannheim (CBTM), Medical Faculty Mannheim, Ruprecht Karl University of Heidelberg, Ludolf-Krehl-Str. 6, 68135 Mannheim, Germany.

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http://dx.doi.org/10.3390/jcm5010008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730133PMC
January 2016

Differentially expressed microRNAs in colorectal cancer metastasis.

Genom Data 2015 Dec 5;6:33-5. Epub 2015 Aug 5.

Department of Experimental Surgery, Medical Faculty Mannheim, University of Heidelberg, Germany ; Centre for Biomedicine and Medical Technology (CBTM), Mannheim, Germany.

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http://dx.doi.org/10.1016/j.gdata.2015.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664671PMC
December 2015

Function and significance of MicroRNAs in benign and malignant human stem cells.

Semin Cancer Biol 2015 Dec 17;35:200-11. Epub 2015 Jul 17.

Department of Experimental Surgery, Medical Faculty Mannheim, Theodor Kutzer Ufer 1-3, 68135 Mannheim, Ruprecht Karl University of Heidelberg, Germany; Centre for Biomedicine and Medical Technology Mannheim (CBTM), Medical Faculty Mannheim, Ludolf-Krehl-Str. 6, 68135 Mannheim, Ruprecht Karl University of Heidelberg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S1044579X150006
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http://dx.doi.org/10.1016/j.semcancer.2015.07.001DOI Listing
December 2015

A Systematic Approach to Defining the microRNA Landscape in Metastasis.

Cancer Res 2015 Aug 11;75(15):3010-9. Epub 2015 Jun 11.

Department of Experimental Surgery, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany. Centre for Biomedicine and Medical Technology Mannheim, Mannheim, Germany.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-0997DOI Listing
August 2015

MicroRNA modulators of epigenetic regulation, the tumor microenvironment and the immune system in lung cancer.

Mol Cancer 2015 Feb 7;14:34. Epub 2015 Feb 7.

Department of Experimental Surgery, Medical Faculty Mannheim, Heidelberg University, Theodor Kutzer Ufer 1-3, 68135, Mannheim, Germany.

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http://dx.doi.org/10.1186/s12943-015-0302-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333888PMC
February 2015

Genetic delivery of an immunoRNase by an oncolytic adenovirus enhances anticancer activity.

Int J Cancer 2015 May 12;136(9):2228-40. Epub 2014 Nov 12.

Oncolytic Adenovirus Group, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 242, 69120 Heidelberg, Germany.

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http://doi.wiley.com/10.1002/ijc.29258
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http://dx.doi.org/10.1002/ijc.29258DOI Listing
May 2015

Gastric cancer patients less than 50 years of age exhibit significant downregulation of E-cadherin and CDX2 compared to older reference populations.

Adv Med Sci 2014 Mar 28;59(1):142-6. Epub 2014 Mar 28.

Department of Experimental Surgery and Molecular Oncology of Solid Tumors, Medical Faculty Mannheim, University Heidelberg and DKFZ Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.advms.2014.03.002DOI Listing
March 2014

MicroRNAs in the Regulation of MMPs and Metastasis.

Cancers (Basel) 2014 Mar 25;6(2):625-45. Epub 2014 Mar 25.

Molecular Oncology of Solid Tumors, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.

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http://dx.doi.org/10.3390/cancers6020625DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074795PMC
March 2014

Src activity is increased in gastrointestinal stromal tumors--analysis of associations with clinical and other molecular tumor characteristics.

J Surg Oncol 2014 May 4;109(6):597-605. Epub 2014 Jan 4.

Department of Surgery, Mannheim Medical Faculty, Heidelberg University, Mannheim, Germany.

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http://doi.wiley.com/10.1002/jso.23544
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http://dx.doi.org/10.1002/jso.23544DOI Listing
May 2014

A mechanistic study on the metastasis inducing function of FUS-CHOP fusion protein in liposarcoma.

Int J Cancer 2014 Jun 7;134(12):2808-19. Epub 2013 Dec 7.

Department of Experimental Surgery and Molecular Oncology of Solid Tumors, Medical Faculty Mannheim, University of Heidelberg and German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.28638DOI Listing
June 2014

The disparate twins: a comparative study of CXCR4 and CXCR7 in SDF-1α-induced gene expression, invasion and chemosensitivity of colon cancer.

Clin Cancer Res 2014 Feb 19;20(3):604-16. Epub 2013 Nov 19.

Authors' Affiliations: Molecular Oncology of Solid Tumors, DKFZ (German Cancer Research Center); Department of Translational Oncology, National Center of Tumor Diseases (NCT) and DKFZ, Heidelberg; Department of Experimental Surgery, Medical Faculty Mannheim; Department of Radiation Oncology, University Medical Centre Mannheim, Medical Faculty Mannheim; Medical Research Center, University Medical Centre Mannheim; Centre for Biomedicine and Medical Technology Mannheim (CBTM), University Medical Centre Mannheim; Institute of Pathology, University Medical Centre Mannheim, University of Heidelberg, Mannheim; KIT Karlsruhe Campus Nord, Eggenstein-Leopoldshafen; and Center for Tumor Diagnostics and Therapy, Paracelsus Klinik, Osnabrueck, Germany.

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http://clincancerres.aacrjournals.org/content/early/2013/11/
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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-13-0582DOI Listing
February 2014

Unraveling the role of FOXQ1 in colorectal cancer metastasis.

Mol Cancer Res 2013 Sep 30;11(9):1017-28. Epub 2013 May 30.

Department of Experimental Surgery, Medical Faculty Mannheim, Ruprecht Karls University Heidelberg and, Molecular Oncology of Solid Tumors Unit, German Cancer Research Center (DKFZ), Heidelberg, Medical Faculty Mannheim, University of Heidelberg, Theodor Kutzer Ufer 1-3, D-68135, Mannheim, Germany.

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http://dx.doi.org/10.1158/1541-7786.MCR-13-0024DOI Listing
September 2013

CXCR4 Expression and Treatment with SDF-1α or Plerixafor Modulate Proliferation and Chemosensitivity of Colon Cancer Cells.

Transl Oncol 2013 Apr 1;6(2):124-32. Epub 2013 Apr 1.

Molecular Oncology of Solid Tumors, German Cancer Research Center (DKFZ), Heidelberg, Germany ; Department of Experimental Surgery, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610551PMC
http://dx.doi.org/10.1593/tlo.12268DOI Listing
April 2013

CD24 induces expression of the oncomir miR-21 via Src, and CD24 and Src are both post-transcriptionally downregulated by the tumor suppressor miR-34a.

PLoS One 2013 22;8(3):e59563. Epub 2013 Mar 22.

Department of Experimental Surgery, University of Heidelberg, Mannheim and Molecular Oncology of Solid Tumors, DKFZ, Heidelberg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0059563PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606220PMC
September 2013

Cetuximab and biomarkers in non-small-cell lung carcinoma.

Biologics 2012 13;6:221-31. Epub 2012 Jul 13.

Department of Experimental Surgery, Medical Faculty Mannheim, University of Heidelberg and Molecular Oncology of Solid Tumors Unit, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.2147/BTT.S24217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3421478PMC
October 2012

MicroRNAs in cancer: small molecules, big chances.

Anticancer Agents Med Chem 2012 Sep;12(7):733-43

Department of Experimental Surgery, Medical Faculty Mannheim, University of Heidelberg, and Molecular Oncology of Solid Tumors Unit, German Cancer Research Center-DKFZ, Heidelberg, Germany.

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http://dx.doi.org/10.2174/187152012802650273DOI Listing
September 2012

Look who's talking: deregulated signaling in colorectal cancer.

Cancer Genomics Proteomics 2012 Jan;9(1):15-25

Department of Experimental Surgery, Medical Faculty Mannheim, University of Heidelberg, Theodor Kutzer Ufer 1-3, 68135 Mannheim, Germany.

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January 2012

MicroRNA-30a inhibits epithelial-to-mesenchymal transition by targeting Snai1 and is downregulated in non-small cell lung cancer.

Int J Cancer 2012 May 8;130(9):2044-53. Epub 2011 Aug 8.

Department of Experimental Surgery Mannheim, University Heidelberg and Molecular Oncology of Solid Tumors, DKFZ Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.26218DOI Listing
May 2012

Editorial: Special section on "site-specific metastasis".

Int J Cancer 2011 Jun;128(11):2509-10

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http://dx.doi.org/10.1002/ijc.26050DOI Listing
June 2011

MicroRNAs-10a and -10b contribute to retinoic acid-induced differentiation of neuroblastoma cells and target the alternative splicing regulatory factor SFRS1 (SF2/ASF).

J Biol Chem 2011 Feb 30;286(6):4150-64. Epub 2010 Nov 30.

Biology of Hormone Action Unit, Department of Molecular and Cellular Pathology and Therapy, Instituto de Biomedicina de Valencia, Consejo Superior de Investigaciones Científicas, Valencia E-46010, Spain.

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http://dx.doi.org/10.1074/jbc.M110.167817DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039334PMC
February 2011

PMA up-regulates the transcription of Axl by AP-1 transcription factor binding to TRE sequences via the MAPK cascade in leukaemia cells.

Biol Cell 2010 Jan;103(1):21-33

Department of Experimental Surgery Mannheim/Molecular Oncology of Solid Tumors, DKFZ and University of Heidelberg, Mannheim 68167, Germany.

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http://dx.doi.org/10.1042/BC20100094DOI Listing
January 2010

Curcumin regulates miR-21 expression and inhibits invasion and metastasis in colorectal cancer.

Biosci Rep 2011 Jun;31(3):185-97

Department of Experimental Surgery, Mannheim Medical Faculty, Ruprecht-Karls-University Heidelberg, 68167 Mannheim, Germany.

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http://bioscirep.org/cgi/doi/10.1042/BSR20100065
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http://dx.doi.org/10.1042/BSR20100065DOI Listing
June 2011

Loss of miR-200c expression induces an aggressive, invasive, and chemoresistant phenotype in non-small cell lung cancer.

Mol Cancer Res 2010 Sep 9;8(9):1207-16. Epub 2010 Aug 9.

Department of Clinical and Biological Sciences, University of Turin at San Luigi Hospital, Orbassano, Italy.

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http://mcr.aacrjournals.org/cgi/doi/10.1158/1541-7786.MCR-10
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http://dx.doi.org/10.1158/1541-7786.MCR-10-0052DOI Listing
September 2010

Modulators of the urokinase-type plasminogen activation system for cancer.

Expert Opin Investig Drugs 2010 May;19(5):641-52

Institut für Pathologie, Bonn, Germany.

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http://dx.doi.org/10.1517/13543781003767400DOI Listing
May 2010

Translational research on u-PAR.

Authors:
Heike Allgayer

Eur J Cancer 2010 May 31;46(7):1241-51. Epub 2010 Mar 31.

Dept. Experimental Surgery/Molecular Oncology of Solid Tumors (Collaboration Unit German Cancer Research Center-DKFZ-Heidelberg), Medical Faculty Mannheim, Ruprecht-Karls-University of Heidelberg, 68167 Mannheim, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S095980491000156
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http://dx.doi.org/10.1016/j.ejca.2010.02.029DOI Listing
May 2010

First evidence that the antimalarial drug artesunate inhibits invasion and in vivo metastasis in lung cancer by targeting essential extracellular proteases.

Int J Cancer 2010 Sep;127(6):1475-85

Department of Experimental Surgery and Molecular Oncology of Solid Tumors, Medical Faculty Mannheim, University of Heidelberg and German Cancer Research Center DKFZ, Heidelberg, Germany.

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http://doi.wiley.com/10.1002/ijc.25315
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http://dx.doi.org/10.1002/ijc.25315DOI Listing
September 2010

Myeloid zinc finger 1 induces migration, invasion, and in vivo metastasis through Axl gene expression in solid cancer.

Mol Cancer Res 2010 Feb 9;8(2):159-69. Epub 2010 Feb 9.

Department of Experimental Surgery/Molecular Oncology of Solid Tumors, DKFZ and University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1158/1541-7786.MCR-09-0326DOI Listing
February 2010

Cold spots in hot spots: transcription start sites of active genes are spared from HIV vector integration.

AIDS 2009 Nov;23(18):2535-7

Clinical Cooperation Unit Molecular Oncology of Solid Tumors, German Cancer Research Center (DKFZ), Germany.

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http://dx.doi.org/10.1097/QAD.0b013e3283336432DOI Listing
November 2009

Pdcd4, a colon cancer prognostic that is regulated by a microRNA.

Authors:
Heike Allgayer

Crit Rev Oncol Hematol 2010 Mar 22;73(3):185-91. Epub 2009 Dec 22.

Dept. Experimental Surgery/Molecular Oncology of Solid Tumors (Collaboration Unit German Cancer Research Center-DKFZ-Heidelberg), Medical Faculty Mannheim, Ruprecht-Karls-University Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.

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http://dx.doi.org/10.1016/j.critrevonc.2009.09.001DOI Listing
March 2010

Urokinase receptor, MMP-1 and MMP-9 are markers to differentiate prognosis, adenoma and carcinoma in thyroid malignancies.

Int J Cancer 2009 Aug;125(4):894-901

Department of Experimental Surgery and Molecular Oncology of Solid Tumors, Mannheim Faculty, University of Heidelberg, and DKFZ Heidelberg, Mannheim, Germany.

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http://doi.wiley.com/10.1002/ijc.24462
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http://dx.doi.org/10.1002/ijc.24462DOI Listing
August 2009

Tumor stroma is the predominant uPA-, uPAR-, PAI-1-expressing tissue in human breast cancer: prognostic impact.

Histol Histopathol 2009 07;24(7):869-77

Institute of Pathology, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.

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http://dx.doi.org/10.14670/HH-24.869DOI Listing
July 2009

Cetuximab attenuates metastasis and u-PAR expression in non-small cell lung cancer: u-PAR and E-cadherin are novel biomarkers of cetuximab sensitivity.

Cancer Res 2009 Mar 10;69(6):2461-70. Epub 2009 Mar 10.

Department of Experimental Surgery and Molecular Oncology of Solid Tumors, Medical Faculty Mannheim, University Heidelberg and DKFZ (German Cancer Research Center), Heidelberg, Germany.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-3236DOI Listing
March 2009

The urokinase receptor (u-PAR)--a link between tumor cell dormancy and minimal residual disease in bone marrow?

APMIS 2008 Jul-Aug;116(7-8):602-14

Department of Experimental Surgery and Molecular Oncology of Solid Tumors, Medical Faculty Mannheim, University of Heidelberg, and DKFZ German Cancer Research Center Heidelberg, Germany.

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http://doi.wiley.com/10.1111/j.1600-0463.2008.00997.x
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http://dx.doi.org/10.1111/j.1600-0463.2008.00997.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821075PMC
November 2008

Molecular targeted therapies for breast cancer treatment.

Breast Cancer Res 2008 24;10(4):211. Epub 2008 Jul 24.

Department of Obstetrics and Gynecology, Breast Centre Klinikum Lüdenscheid, Academic Teaching Hospital of the University Bonn, Luedenscheid, Paulmannshoeher Str, 14 - 58515 Luedenscheid Germany.

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http://breast-cancer-research.biomedcentral.com/articles/10.
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http://dx.doi.org/10.1186/bcr2112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575526PMC
April 2009

The human receptor tyrosine kinase Axl gene--promoter characterization and regulation of constitutive expression by Sp1, Sp3 and CpG methylation.

Biosci Rep 2008 Jun;28(3):161-76

Department of Experimental Surgery Mannheim/Molecular Oncology of Solid Tumors, Mannheim Medical Faculty, Ruprecht-Karls-University Heidelberg, German Cancer Research Center-DKFZ-Heidelberg, 68167 Mannheim, Germany.

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http://dx.doi.org/10.1042/BSR20080046DOI Listing
June 2008

NRF-1, and AP-1 regulate the promoter of the human calpain small subunit 1 (CAPNS1) gene.

Gene 2008 Feb 23;410(1):197-206. Epub 2007 Dec 23.

Department Experimental Surgery Mannheim, University Heidelberg, and Molecular Oncology of Solid Tumors Unit, German Cancer Research Center (DKFZ) Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.gene.2007.12.009DOI Listing
February 2008

The urokinase-system--role of cell proliferation and apoptosis.

Histol Histopathol 2008 02;23(2):227-36

Department of Pathology, University Hospital, Mannheim, Germany.

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http://dx.doi.org/10.14670/HH-23.227DOI Listing
February 2008

Loss of programmed cell death 4 expression marks adenoma-carcinoma transition, correlates inversely with phosphorylated protein kinase B, and is an independent prognostic factor in resected colorectal cancer.

Cancer 2007 Oct;110(8):1697-707

Department of Experimental Surgery Mannheim/Molecular Oncology of Solid Tumors, Deutsches Krebsforschungszentrum and University Heidelberg, Mannheim, Germany.

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http://dx.doi.org/10.1002/cncr.22983DOI Listing
October 2007

Src induces urokinase receptor gene expression and invasion/intravasation via activator protein-1/p-c-Jun in colorectal cancer.

Mol Cancer Res 2007 May;5(5):485-96

Department of Experimental Surgery Mannheim Faculty, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1158/1541-7786.MCR-06-0211DOI Listing
May 2007

Analysis of specific transcriptional regulators as early predictors of independent prognostic relevance in resected colorectal cancer.

Clin Cancer Res 2007 Feb;13(4):1123-32

Department of Experimental Surgery and Molecular Oncology of Solid Tumors (German Cancer Research Center), Mannheim Faculty University Heidelberg, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-06-1668DOI Listing
February 2007

Urokinase-receptor (u-PAR): an essential player in multiple games of cancer: a review on its role in tumor progression, invasion, metastasis, proliferation/dormancy, clinical outcome and minimal residual disease.

Cell Cycle 2006 Aug 15;5(16):1760-71. Epub 2006 Aug 15.

Department of Experimental Surgery and Molecular Oncology, Klinikum Mannheim, Joint Unit Molecular Oncology of Solid Tumors, German Cancer Research Center Heidelberg.

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http://dx.doi.org/10.4161/cc.5.16.2994DOI Listing
August 2006

Molecular regulation of an invasion-related molecule--options for tumour staging and clinical strategies.

Authors:
Heike Allgayer

Eur J Cancer 2006 May 17;42(7):811-9. Epub 2006 Apr 17.

Department of Experimental Surgery and Molecular Oncology, Klinikum Mannheim, Ruprecht Karls University Heidelberg, Theodor Kutzer Ufer 1-3, 68135 Mannheim, Germany.

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http://dx.doi.org/10.1016/j.ejca.2006.01.018DOI Listing
May 2006

Combination analysis of activator protein-1 family members, Sp1 and an activator protein-2alpha-related factor binding to different regions of the urokinase receptor gene in resected colorectal cancers.

Clin Cancer Res 2005 Dec;11(24 Pt 1):8538-48

Department of Experimental Surgery and Molecular Oncology, Universitaetsklinikum Mannheim and Department of Pediatrics, Dr. v. Haunersches Kinderspital, Munich, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-05-0786DOI Listing
December 2005

TaqMan-based quantification of invasive cells in the chick embryo metastasis assay.

Biotechniques 2004 Dec;37(6):940-2, 944, 946

U3Pharma, Martinsried, Germany.

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http://dx.doi.org/10.2144/04376ST02DOI Listing
December 2004

Transcriptional regulation of the urokinase receptor (u-PAR)--a central molecule of invasion and metastasis.

Biol Chem 2003 May;384(5):755-61

Department of Surgery, Grosshadern Clinic, Ludwig-Maximilians University of Munich, Marchioninistr. 15, D-81377 Munich, Germany.

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http://dx.doi.org/10.1515/BC.2003.084DOI Listing
May 2003

Summary and congress report: molecular staging of cancer--concepts of today, therapies of tomorrow.

Recent Results Cancer Res 2003 ;162:211-7

Department of Surgery, Klinikum Grosshadern, Ludwig Maximilians University of Munich, Marchioninistr. 15, 81377 Munich, Germany.

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http://dx.doi.org/10.1007/978-3-642-59349-9_21DOI Listing
September 2003

Molecular regulation of urokinase-receptor gene expression as one potential concept for molecular staging and therapy.

Authors:
Heike Allgayer

Recent Results Cancer Res 2003 ;162:15-30

Department of Surgery, Klinikum Grosshadern, Ludwig Maximilians University of Munich, Marchioninistr. 15, 81377 Munich, Germany.

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http://dx.doi.org/10.1007/978-3-642-59349-9_2DOI Listing
September 2003

Molecular staging of cancer: concepts of today, therapies of tomorrow.

Authors:
Heike Allgayer

J Surg Oncol 2003 Apr;82(4):217-23

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http://dx.doi.org/10.1002/jso.10226DOI Listing
April 2003