Heidrun Gevensleben

Heidrun Gevensleben

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Heidrun Gevensleben

Heidrun Gevensleben

Publications by authors named "Heidrun Gevensleben"

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Comparison of quantification algorithms for circulating cell-free DNA methylation biomarkers in blood plasma from cancer patients.

Clin Epigenetics 2017 1;9:125. Epub 2017 Dec 1.

Department of Otolaryngology, University Hospital Bonn, Head and Neck Surgery, Sigmund-Freud-Str. 25, 53127 Bonn, Germany.

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http://dx.doi.org/10.1186/s13148-017-0425-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709918PMC
September 2018

Prostate-specific membrane antigen in breast cancer: a comprehensive evaluation of expression and a case report of radionuclide therapy.

Breast Cancer Res Treat 2018 Jun 17;169(3):447-455. Epub 2018 Feb 17.

Institute of Pathology, Center for Integrated Oncology, University Hospital Bonn, University of Bonn, Sigmund-Freud-Str. 25, 53127, Bonn, Germany.

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http://dx.doi.org/10.1007/s10549-018-4717-yDOI Listing
June 2018

PITX2 DNA Methylation as Biomarker for Individualized Risk Assessment of Prostate Cancer in Core Biopsies.

J Mol Diagn 2017 01 8;19(1):107-114. Epub 2016 Dec 8.

Institute of Pathology, University Hospital Bonn, Bonn, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2016.08.008DOI Listing
January 2017

Prophylactic total gastrectomy in the management of hereditary tumor syndromes.

Int J Colorectal Dis 2016 Dec 28;31(12):1825-1833. Epub 2016 Sep 28.

Department of General, Visceral, Thoracic and Vascular Surgery, University Hospital of Bonn, Bonn, Germany.

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http://dx.doi.org/10.1007/s00384-016-2656-9DOI Listing
December 2016

Mechanisms of Therapy Resistance in Patient-Derived Xenograft Models of BRCA1-Deficient Breast Cancer.

J Natl Cancer Inst 2016 11 5;108(11). Epub 2016 Jul 5.

Affiliations of authors: Division of Molecular Pathology and Cancer Genomics Centre Netherlands (PtB, PK, EvdB, UB, MdM, EL, LM, JdR, JW, JJ), Division of Molecular Carcinogenesis (IM), Department of Epidemiology and Biostatistics (KJ), and Family Cancer Clinic and Department of Pathology (FH), The Netherlands Cancer Institute, Amsterdam, the Netherlands; Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Catalonia, Spain (CM, ME); The Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London, UK (HG, NT); Laboratory of Preclinical Investigation, Translational Research Department, Curie Institute, Paris, France (EM); Department of Medical Genetics, University Medical Center Utrecht, Utrecht, the Netherlands (WK, MvR, KD, EC); Department of Physiological Sciences II, School of Medicine, University of Barcelona, Barcelona, Catalonia, Spain (ME); Institucio Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Catalonia, Spain (ME).

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http://dx.doi.org/10.1093/jnci/djw148DOI Listing
November 2016

() promoter methylation predicts survival in colorectal cancer patients.

Oncoimmunology 2017 10;6(1):e1257454. Epub 2016 Nov 10.

Institute of Pathology, University Hospital Bonn, Bonn, Germany; Department of Otolaryngology, Head and Neck Surgery, University Hospital Bonn, Bonn, Germany.

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http://dx.doi.org/10.1080/2162402X.2016.1257454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283627PMC
November 2016

The emerging role of non-coding circulating RNA as a biomarker in renal cell carcinoma.

Expert Rev Mol Diagn 2016 10 27;16(10):1059-1065. Epub 2016 Sep 27.

b Institute of Pathology , University Hospital Bonn , Bonn , Germany.

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http://dx.doi.org/10.1080/14737159.2016.1239531DOI Listing
October 2016

Promoter methylation of the immune checkpoint receptor () is an independent prognostic biomarker for biochemical recurrence-free survival in prostate cancer patients following radical prostatectomy.

Oncoimmunology 2016 2;5(10):e1221555. Epub 2016 Sep 2.

Institute of Pathology, University Hospital Bonn, Bonn, Germany; Department of Otolaryngology, Head and Neck Surgery, University Hospital Bonn, Bonn, Germany.

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http://dx.doi.org/10.1080/2162402X.2016.1221555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087295PMC
September 2016

The Significance of Accurate Determination of Gleason Score for Therapeutic Options and Prognosis of Prostate Cancer.

Pathol Oncol Res 2016 Apr 12;22(2):349-56. Epub 2015 Nov 12.

Department of Urology, Hegau-Bodensee Hospital of Singen, Singen, Germany.

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http://dx.doi.org/10.1007/s12253-015-0013-xDOI Listing
April 2016

Loss of the LIM-only protein Fhl2 impairs inflammatory reaction and scar formation after cardiac ischemia leading to better hemodynamic performance.

Life Sci 2016 Apr 24;151:348-358. Epub 2016 Feb 24.

Institute of Pathology, University of Cologne, Kerpener Str. 62, 50937 Cologne, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.lfs.2016.02.084DOI Listing
April 2016

Pathological features of breast and ovarian cancers in RAD51C germline mutation carriers.

Virchows Arch 2014 Sep 4;465(3):365-9. Epub 2014 Jul 4.

Institute of Pathology, University Hospital Bonn, Sigmund-Freud-Strasse 25, 53127, Bonn, Germany,

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http://link.springer.com/10.1007/s00428-014-1619-1
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http://dx.doi.org/10.1007/s00428-014-1619-1DOI Listing
September 2014

Noninvasive detection of HER2 amplification with plasma DNA digital PCR.

Clin Cancer Res 2013 Jun 1;19(12):3276-84. Epub 2013 May 1.

The Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London, United Kingdom.

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http://dx.doi.org/10.1158/1078-0432.CCR-12-3768DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485473PMC
June 2013

Transcription factors link mouse WAP-T mammary tumors with human breast cancer.

Int J Cancer 2013 Mar 13;132(6):1311-22. Epub 2012 Dec 13.

Department of Clinical Chemistry, Center for Diagnostic, University Medical Center Hamburg-Eppendorf, D-20246 Hamburg, Germany.

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http://dx.doi.org/10.1002/ijc.27941DOI Listing
March 2013

Prognostic impact of fascin-1 (FSCN1) in epithelial ovarian cancer.

Anticancer Res 2013 Feb;33(2):371-7

Department of Obstetrics and Gynecology, J.W. Goethe University, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.

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February 2013

Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2.

Authors:
Anna Marie Mulligan Fergus J Couch Daniel Barrowdale Susan M Domchek Diana Eccles Heli Nevanlinna Susan J Ramus Mark Robson Mark Sherman Amanda B Spurdle Barbara Wappenschmidt Andrew Lee Lesley McGuffog Sue Healey Olga M Sinilnikova Ramunas Janavicius Thomas vO Hansen Finn C Nielsen Bent Ejlertsen Ana Osorio Iván Muñoz-Repeto Mercedes Durán Javier Godino Maroulio Pertesi Javier Benítez Paolo Peterlongo Siranoush Manoukian Bernard Peissel Daniela Zaffaroni Elisa Cattaneo Bernardo Bonanni Alessandra Viel Barbara Pasini Laura Papi Laura Ottini Antonella Savarese Loris Bernard Paolo Radice Ute Hamann Martijn Verheus Hanne E J Meijers-Heijboer Juul Wijnen Encarna B Gómez García Marcel R Nelen C Marleen Kets Caroline Seynaeve Madeleine M A Tilanus-Linthorst Rob B van der Luijt Theo van Os Matti Rookus Debra Frost J Louise Jones D Gareth Evans Fiona Lalloo Ros Eeles Louise Izatt Julian Adlard Rosemarie Davidson Jackie Cook Alan Donaldson Huw Dorkins Helen Gregory Jacqueline Eason Catherine Houghton Julian Barwell Lucy E Side Emma McCann Alex Murray Susan Peock Andrew K Godwin Rita K Schmutzler Kerstin Rhiem Christoph Engel Alfons Meindl Ina Ruehl Norbert Arnold Dieter Niederacher Christian Sutter Helmut Deissler Dorothea Gadzicki Karin Kast Sabine Preisler-Adams Raymonda Varon-Mateeva Ines Schoenbuchner Britta Fiebig Wolfram Heinritz Dieter Schäfer Heidrun Gevensleben Virginie Caux-Moncoutier Marion Fassy-Colcombet François Cornelis Sylvie Mazoyer Mélanie Léoné Nadia Boutry-Kryza Agnès Hardouin Pascaline Berthet Danièle Muller Jean-Pierre Fricker Isabelle Mortemousque Pascal Pujol Isabelle Coupier Marine Lebrun Caroline Kientz Michel Longy Nicolas Sevenet Dominique Stoppa-Lyonnet Claudine Isaacs Trinidad Caldes Miguel de la Hoya Tuomas Heikkinen Kristiina Aittomäki Ignacio Blanco Conxi Lazaro Rosa B Barkardottir Penny Soucy Martine Dumont Jacques Simard Marco Montagna Silvia Tognazzo Emma D'Andrea Stephen Fox Max Yan Tim Rebbeck Olufunmilayo Olopade Jeffrey N Weitzel Henry T Lynch Patricia A Ganz Gail E Tomlinson Xianshu Wang Zachary Fredericksen Vernon S Pankratz Noralane M Lindor Csilla Szabo Kenneth Offit Rita Sakr Mia Gaudet Jasmine Bhatia Noah Kauff Christian F Singer Muy-Kheng Tea Daphne Gschwantler-Kaulich Anneliese Fink-Retter Phuong L Mai Mark H Greene Evgeny Imyanitov Frances P O'Malley Hilmi Ozcelik Gordon Glendon Amanda E Toland Anne-Marie Gerdes Mads Thomassen Torben A Kruse Uffe Birk Jensen Anne-Bine Skytte Maria A Caligo Maria Soller Karin Henriksson von Anna Wachenfeldt Brita Arver Marie Stenmark-Askmalm Per Karlsson Yuan Chun Ding Susan L Neuhausen Mary Beattie Paul D P Pharoah Kirsten B Moysich Katherine L Nathanson Beth Y Karlan Jenny Gross Esther M John Mary B Daly Saundra M Buys Melissa C Southey John L Hopper Mary Beth Terry Wendy Chung Alexander F Miron David Goldgar Georgia Chenevix-Trench Douglas F Easton Irene L Andrulis Antonis C Antoniou

Breast Cancer Res 2011 2;13(6):R110. Epub 2011 Nov 2.

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, 2 Worts Causeway, Cambridge, CB1 8RN, UK.

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http://dx.doi.org/10.1186/bcr3052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326552PMC
June 2012

Forced mitotic entry of S-phase cells as a therapeutic strategy induced by inhibition of WEE1.

Cancer Discov 2012 Jun 23;2(6):524-39. Epub 2012 Apr 23.

The Breakthrough Breast Cancer Research Centre, Institute of Cancer Research; Breast Unit, UK.

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http://dx.doi.org/10.1158/2159-8290.CD-11-0320DOI Listing
June 2012

Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA).

Authors:
Nasim Mavaddat Daniel Barrowdale Irene L Andrulis Susan M Domchek Diana Eccles Heli Nevanlinna Susan J Ramus Amanda Spurdle Mark Robson Mark Sherman Anna Marie Mulligan Fergus J Couch Christoph Engel Lesley McGuffog Sue Healey Olga M Sinilnikova Melissa C Southey Mary Beth Terry David Goldgar Frances O'Malley Esther M John Ramunas Janavicius Laima Tihomirova Thomas V O Hansen Finn C Nielsen Ana Osorio Alexandra Stavropoulou Javier Benítez Siranoush Manoukian Bernard Peissel Monica Barile Sara Volorio Barbara Pasini Riccardo Dolcetti Anna Laura Putignano Laura Ottini Paolo Radice Ute Hamann Muhammad U Rashid Frans B Hogervorst Mieke Kriege Rob B van der Luijt Susan Peock Debra Frost D Gareth Evans Carole Brewer Lisa Walker Mark T Rogers Lucy E Side Catherine Houghton JoEllen Weaver Andrew K Godwin Rita K Schmutzler Barbara Wappenschmidt Alfons Meindl Karin Kast Norbert Arnold Dieter Niederacher Christian Sutter Helmut Deissler Doroteha Gadzicki Sabine Preisler-Adams Raymonda Varon-Mateeva Ines Schönbuchner Heidrun Gevensleben Dominique Stoppa-Lyonnet Muriel Belotti Laure Barjhoux Claudine Isaacs Beth N Peshkin Trinidad Caldes Miguel de la Hoya Carmen Cañadas Tuomas Heikkinen Päivi Heikkilä Kristiina Aittomäki Ignacio Blanco Conxi Lazaro Joan Brunet Bjarni A Agnarsson Adalgeir Arason Rosa B Barkardottir Martine Dumont Jacques Simard Marco Montagna Simona Agata Emma D'Andrea Max Yan Stephen Fox Timothy R Rebbeck Wendy Rubinstein Nadine Tung Judy E Garber Xianshu Wang Zachary Fredericksen Vernon S Pankratz Noralane M Lindor Csilla Szabo Kenneth Offit Rita Sakr Mia M Gaudet Christian F Singer Muy-Kheng Tea Christine Rappaport Phuong L Mai Mark H Greene Anna Sokolenko Evgeny Imyanitov Amanda Ewart Toland Leigha Senter Kevin Sweet Mads Thomassen Anne-Marie Gerdes Torben Kruse Maria Caligo Paolo Aretini Johanna Rantala Anna von Wachenfeld Karin Henriksson Linda Steele Susan L Neuhausen Robert Nussbaum Mary Beattie Kunle Odunsi Lara Sucheston Simon A Gayther Kate Nathanson Jenny Gross Christine Walsh Beth Karlan Georgia Chenevix-Trench Douglas F Easton Antonis C Antoniou

Cancer Epidemiol Biomarkers Prev 2012 Jan 5;21(1):134-47. Epub 2011 Dec 5.

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.1158/1055-9965.EPI-11-0775DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272407PMC
January 2012

Preterm diagnosis of choristoma and choroidal coloboma in Goldenhar's syndrome.

Pediatr Dev Pathol 2011 Jul-Aug;14(4):322-6. Epub 2011 Feb 23.

Department of Ophthalmology, University of Bonn, Ernst-Abbe-Str. 2, Bonn, Germany.

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http://dx.doi.org/10.2350/10-07-0874-CR.1DOI Listing
December 2011

Risk-reducing salpingo-oophorectomy in BRCA1 and BRCA2 mutation carriers.

Arch Gynecol Obstet 2011 Mar 29;283(3):623-7. Epub 2010 Apr 29.

Center for Familial Breast and Ovarian Cancer, Department of Obstetrics and Gynecology, University of Cologne School of Medicine, Kerpener Str. 62, 50937 Cologne, Germany.

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http://dx.doi.org/10.1007/s00404-010-1476-3DOI Listing
March 2011