Hee-Jung An

Hee-Jung An

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Hee-Jung An

Hee-Jung An

Publications by authors named "Hee-Jung An"

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Integrative analysis of transcription factors and microRNAs in ovarian cancer cell spheroids.

J Ovarian Res 2020 Feb 11;13(1):16. Epub 2020 Feb 11.

Department of Pathology, College of Medicine, CHA University, Seongnam, 351 Yatap-dong, Bundang-gu, Seongnam-si, Gyeonggi-do, 13496, South Korea.

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http://dx.doi.org/10.1186/s13048-020-00618-7DOI Listing
February 2020

Immune gene signatures for predicting durable clinical benefit of anti-PD-1 immunotherapy in patients with non-small cell lung cancer.

Sci Rep 2020 Jan 20;10(1):643. Epub 2020 Jan 20.

Department of Pathology, CHA University, CHA Bundang Medical Center, Seongnam-si, Kyeonggi-do, Republic of Korea.

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http://dx.doi.org/10.1038/s41598-019-57218-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971301PMC
January 2020

Clinical Impact of Somatic Variants in Homologous Recombination Repair-Related Genes in Ovarian High-Grade Serous Carcinoma.

Cancer Res Treat 2020 Jan 6. Epub 2020 Jan 6.

Center for Cancer Precision Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea.

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http://dx.doi.org/10.4143/crt.2019.207DOI Listing
January 2020

Multifunctional nanoparticles for genetic engineering and bioimaging of natural killer (NK) cell therapeutics.

Biomaterials 2019 Nov 9;221:119418. Epub 2019 Aug 9.

Department of Biomedical Science, CHA University, 335 Pangyo-ro, Bundang-gu, Seongnam, Gyeonggi 13488, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2019.119418DOI Listing
November 2019

Molecular mechanisms of resistance to CDK4/6 inhibitors in breast cancer: A review.

Int J Cancer 2019 09 7;145(5):1179-1188. Epub 2019 Jan 7.

Medical Oncology, Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, South Korea.

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http://doi.wiley.com/10.1002/ijc.32020
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http://dx.doi.org/10.1002/ijc.32020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767051PMC
September 2019

Correction to: IL-27 enhances IL-15/IL-18-mediated activation of human natural killer cells.

J Immunother Cancer 2019 Aug 8;7(1):211. Epub 2019 Aug 8.

Institute for Clinical Research, CHA Bundang Medical Center, CHA University, Sungnam, Gyeonggi-do, Republic of Korea.

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http://dx.doi.org/10.1186/s40425-019-0688-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686217PMC
August 2019

IL-27 enhances IL-15/IL-18-mediated activation of human natural killer cells.

J Immunother Cancer 2019 Jul 5;7(1):168. Epub 2019 Jul 5.

Institute for Clinical Research, CHA Bundang Medical Center, CHA University, Sungnam, Gyeonggi-do, Republic of Korea.

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http://dx.doi.org/10.1186/s40425-019-0652-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612093PMC
July 2019

Serum exosomal miRNA-145 and miRNA-200c as promising biomarkers for preoperative diagnosis of ovarian carcinomas.

J Cancer 2019 12;10(9):1958-1967. Epub 2019 May 12.

Department of Pathology, CHA Bundang Medical Center, CHA University, 59 Yatap-ro, Bundang-gu Seongnam-si Gyeonggi-do 13496, Republic of Korea.

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http://dx.doi.org/10.7150/jca.30231DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548168PMC
May 2019

A novel PI3K/mTOR dual inhibitor, CMG002, overcomes the chemoresistance in ovarian cancer.

Gynecol Oncol 2019 04 25;153(1):135-148. Epub 2019 Jan 25.

Department of Pathology, CHA Bundang Medical Center, CHA University, Republic of Korea; Institute for Clinical Research, CHA Bundang Medical Center, CHA University, Republic of Korea. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00908258193004
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http://dx.doi.org/10.1016/j.ygyno.2019.01.012DOI Listing
April 2019

miR-150 enhances apoptotic and anti-tumor effects of paclitaxel in paclitaxel-resistant ovarian cancer cells by targeting Notch3.

Oncotarget 2017 Sep 18;8(42):72788-72800. Epub 2017 Aug 18.

Department of Pathology, CHA Bundang Medical Center, CHA University, Gyeonggi-do, Korea.

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http://dx.doi.org/10.18632/oncotarget.20348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641169PMC
September 2017

Clinical Impact of microRNAs Associated With Cancer Stem Cells as a Prognostic Factor in Ovarian Carcinoma.

J Cancer 2017 30;8(17):3538-3547. Epub 2017 Sep 30.

Department of Pathology, CHA University, Sungnam, Republic of Korea.

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http://dx.doi.org/10.7150/jca.20348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687169PMC
September 2017

Fascin expression is inversely correlated with breast cancer metastasis suppressor 1 and predicts a worse survival outcome in node-negative breast cancer patients.

J Cancer 2017 6;8(16):3122-3129. Epub 2017 Sep 6.

Department of Pathology, CHA Bundang Medical Center, CHA University, 59 Yatap-ro, Bundang-gu, Seongnam-si, Gyeonggi-do, 13496, Korea.

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http://dx.doi.org/10.7150/jca.22046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665027PMC
September 2017

Correlation of Expression: Clinical implication in Ovarian Carcinomas.

J Cancer 2017 20;8(16):3331-3342. Epub 2017 Sep 20.

Institute for Clinical Research, College of Medicine, CHA University, Yatap-dong, Seongnam Si Bundang-gu, Gyeonggi-Do 463-712, Republic of Korea.

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http://dx.doi.org/10.7150/jca.18955DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665050PMC
September 2017

MicroRNA-136 inhibits cancer stem cell activity and enhances the anti-tumor effect of paclitaxel against chemoresistant ovarian cancer cells by targeting Notch3.

Cancer Lett 2017 02 22;386:168-178. Epub 2016 Nov 22.

Department of Pathology, CHA Bundang Medical Center, CHA University, 463-712, South Korea; Institute for Clinical Research, CHA Bundang Medical Center, CHA University, 463-712, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2016.11.017DOI Listing
February 2017

Notch3-specific inhibition using siRNA knockdown or GSI sensitizes paclitaxel-resistant ovarian cancer cells.

Mol Carcinog 2016 07 24;55(7):1196-209. Epub 2015 Jul 24.

Department of Pathology, CHA Bundang Medical Center, CHA University, Seongnam-si, South Korea.

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http://dx.doi.org/10.1002/mc.22363DOI Listing
July 2016

Spermatic Cord Paraganglioma With Histologically Malignant Features.

Urology 2016 Jul 22;93:e7-8. Epub 2016 Mar 22.

Department of Urology, CHA Bundang Medical Center, CHA University, Seongnam-si, Gyeonggi-do, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.urology.2016.03.014DOI Listing
July 2016

Sox10 expression in ovarian epithelial tumors is associated with poor overall survival.

Virchows Arch 2016 May 7;468(5):597-605. Epub 2016 Mar 7.

Department of Pathology, College of Medicine, CHA University, 351 Yatap-dong, Bundang-gu, Seongnam-si, Gyeonggi-do, 463-712, South Korea.

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http://dx.doi.org/10.1007/s00428-016-1918-9DOI Listing
May 2016

Fibulin-5 is a tumour suppressor inhibiting cell migration and invasion in ovarian cancer.

J Clin Pathol 2016 Feb 6;69(2):109-16. Epub 2015 Aug 6.

Department of Pathology, CHA Bundang Medical Center, CHA University, Sungnam, Korea Clinical Research Institute, CHA Bundang Medical Center, CHA University, Sungnam, Korea.

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http://dx.doi.org/10.1136/jclinpath-2015-203129DOI Listing
February 2016

Hsa-miR-1246 and hsa-miR-1290 are associated with stemness and invasiveness of non-small cell lung cancer.

Lung Cancer 2016 Jan 17;91:15-22. Epub 2015 Nov 17.

Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, CHA Bundang Medical Center, College of Medicine, CHA University, 59 Yatap-ro, Bundang-gu, Seongnam 463-712, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2015.11.013DOI Listing
January 2016

Intrahepatic Cholangiocarcinoma with Ductal Plate Malformation-like Feature Associated with Bile Duct Adenoma.

J Pathol Transl Med 2015 Nov 31;49(6):531-4. Epub 2015 Jul 31.

Department of Pathology, CHA Bundang Medical Center, CHA University, Seongnam, Korea.

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http://dx.doi.org/10.4132/jptm.2015.06.19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696523PMC
November 2015

VAV3 Overexpressed in Cancer Stem Cells Is a Poor Prognostic Indicator in Ovarian Cancer Patients.

Stem Cells Dev 2015 Jul 9;24(13):1521-35. Epub 2015 Apr 9.

1 Department of Pathology, College of Medicine, CHA University , Sungnam, Republic of Korea.

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http://dx.doi.org/10.1089/scd.2014.0588DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499777PMC
July 2015

miR-145, targeting high-mobility group A2, is a powerful predictor of patient outcome in ovarian carcinoma.

Cancer Lett 2015 Jan 10;356(2 Pt B):937-45. Epub 2014 Nov 10.

Department of Pathology, CHA Bundang Medical Center, CHA University, 59 Yatap-rho, Bundang-gu, Seongnam-si, Gyeonggi-do 463-712, Republic of Korea; Institute for Clinical Research, CHA Bundang Medical Center, CHA University, 59 Yatap-rho, Bundang-gu, Seongnam-si, Gyeonggi-do 463-712, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2014.11.011DOI Listing
January 2015

Dysregulated microRNA expression in adenocarcinoma of the uterine cervix: clinical impact of miR-363-3p.

Gynecol Oncol 2014 Dec 16;135(3):565-72. Epub 2014 Sep 16.

Institute for Clinical Research, CHA University, Sungnam, Republic of Korea; Department of Pathology, CHA University, Sungnam, Republic of Korea.

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http://dx.doi.org/10.1016/j.ygyno.2014.09.010DOI Listing
December 2014

Overexpression of goosecoid homeobox is associated with chemoresistance and poor prognosis in ovarian carcinoma.

Oncol Rep 2014 Jul 20;32(1):189-98. Epub 2014 May 20.

Institute for Clinical Research, College of Medicine, CHA University, Sungnam 463-712, Republic of Korea.

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http://dx.doi.org/10.3892/or.2014.3203DOI Listing
July 2014

Fascin1 expression in high-grade serous ovarian carcinoma is a prognostic marker and knockdown of fascin1 suppresses the proliferation of ovarian cancer cells.

Int J Oncol 2014 Mar 30;44(3):637-46. Epub 2013 Dec 30.

Clinical Research Institute, CHA University, Bundang-Gu, Seongnam-Si, Gyeonggi-Do 463-712, Republic of Korea.

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http://dx.doi.org/10.3892/ijo.2013.2232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928475PMC
March 2014

Targeted inhibition of phosphatidyl inositol-3-kinase p110β, but not p110α, enhances apoptosis and sensitivity to paclitaxel in chemoresistant ovarian cancers.

Apoptosis 2013 Apr;18(4):509-20

Department of Pathology, College of Medicine, CHA University, 351 Yatap-dong, Gyeonggi-Do, Seongnam Si Bundang-gu 463-712, Republic of Korea.

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http://dx.doi.org/10.1007/s10495-013-0807-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3604599PMC
April 2013

MicroRNAs overexpressed in ovarian ALDH1-positive cells are associated with chemoresistance.

J Ovarian Res 2013 Mar 22;6(1):18. Epub 2013 Mar 22.

Department of Pathology, CHA University, Sungnam, 463-712, South Korea.

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http://dx.doi.org/10.1186/1757-2215-6-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637599PMC
March 2013

Notch3 and Jagged2 contribute to gastric cancer development and to glandular differentiation associated with MUC2 and MUC5AC expression.

Histopathology 2012 Oct;61(4):576-86

Department of PathologyClinical Research InstituteDepartment of Surgery, CHA Bundang Medical Center, CHA University, Seongnam-si, Gyeonggi-do, Korea.

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http://dx.doi.org/10.1111/j.1365-2559.2012.04274.xDOI Listing
October 2012

Effects of corticosteroid on the expressions of neuropeptide and cytokine mRNA and on tenocyte viability in lateral epicondylitis.

J Inflamm (Lond) 2012 Oct 30;9(1):40. Epub 2012 Oct 30.

Department of Orthopaedic Surgery, CHA Bundang Medical Center, CHA University, Gyeonggi-do, 463-712, Korea.

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http://dx.doi.org/10.1186/1476-9255-9-40DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551708PMC
October 2012

P2Y receptors regulate proliferation of human pancreatic duct epithelial cells.

Pancreas 2012 Jul;41(5):797-803

Departments of Physiology, School of Medicine, CHA University, Seongnam, Gyeonggi, Republic of Korea.

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http://dx.doi.org/10.1097/MPA.0b013e31823ba3b3DOI Listing
July 2012

Significance of cell cycle regulatory proteins as malignant and prognostic biomarkers in ovarian epithelial tumors.

Int J Gynecol Pathol 2011 May;30(3):205-17

Department of Pathology, CHA Gangnam Medical Center, CHA University, Seoul, Korea.

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http://dx.doi.org/10.1097/PGP.0b013e3182063e71DOI Listing
May 2011

Laminin-332-rich tumor microenvironment for tumor invasion in the interface zone of breast cancer.

Am J Pathol 2011 Jan 23;178(1):373-81. Epub 2010 Dec 23.

Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1016/j.ajpath.2010.11.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069863PMC
January 2011

Proteomic identification of paclitaxel-resistance associated hnRNP A2 and GDI 2 proteins in human ovarian cancer cells.

J Proteome Res 2010 Nov 15;9(11):5668-76. Epub 2010 Oct 15.

Department of Physiology, CHA University, Sungnam, South Korea.

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http://dx.doi.org/10.1021/pr100478uDOI Listing
November 2010

Deregulation of miR-519a, 153, and 485-5p and its clinicopathological relevance in ovarian epithelial tumours.

Histopathology 2010 Nov;57(5):734-43

Department of Pathology, CHA Bundang Medical Center, CHA University, Seongnam-si, Gyeonggi-do, Korea.

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http://dx.doi.org/10.1111/j.1365-2559.2010.03686.xDOI Listing
November 2010

Polymorphisms of thymidylate synthase gene 5'- and 3'-untranslated region and risk of gastric cancer in Koreans.

Anticancer Res 2010 Jun;30(6):2325-30

Institute for Clinical Research, CHA Bundang Medical Center, School of Medicine, CHA University, Seongnam, 463-712, South Korea.

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June 2010

Proteomic identification of overexpressed PRDX 1 and its clinical implications in ovarian carcinoma.

J Proteome Res 2010 Jan;9(1):451-7

Department of Biochemistry, College of Medicine, and College of Life Science, CHA University, Sungnam, South Korea.

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http://dx.doi.org/10.1021/pr900811xDOI Listing
January 2010

Glassy cell carcinoma predominantly commits to a squamous lineage and is strongly associated with high-risk type human papillomavirus infection.

Int J Gynecol Pathol 2009 Jul;28(4):389-95

Department of Pathology, Yonsei University College of Medicine, Seoul, Republic of Korea.

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http://dx.doi.org/10.1097/PGP.0b013e31819343a5DOI Listing
July 2009

Imup-1 and imup-2 overexpression in endometrial carcinoma in Korean and Japanese populations.

Anticancer Res 2008 Mar-Apr;28(2A):865-71

Department of Obstetrics and Gynecology, College of Medicine, Pochon CHA University, Sungnam, Korea.

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June 2008

Gender-specific association of the VEGF -2578C > A polymorphism in Korean patients with colon cancer.

Anticancer Res 2007 Jul-Aug;27(4B):2535-9

Institute for Clinical Research, Bundang CHA General Hospital, College of Medicine, Pochon CHA University, Seongnam, South Korea.

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September 2007

[A case of hemophagocytic syndrome with terminal ileal ulcerations].

Korean J Gastroenterol 2006 Sep;48(3):205-9

Department of Internal Medicine, Bundang CHA Hospital, Pochon CHA University, Yatap-dong, Bundang-gu, Seongnam, Korea.

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September 2006

Comparative proteomics of ovarian epithelial tumors.

J Proteome Res 2006 May;5(5):1082-90

Department of Pathology, Pocheon CHA University, Korea.

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http://dx.doi.org/10.1021/pr050461pDOI Listing
May 2006

Elevation of cyclin B1, active cdc2, and HuR in cervical neoplasia with human papillomavirus type 18 infection.

Cancer Lett 2006 Feb;232(2):170-8

Department of Pathology, Yonsei University College of Medicine, Seodaemoon-ku, Shinchon-dong 134, Seoul 120-752, South Korea.

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http://dx.doi.org/10.1016/j.canlet.2005.02.026DOI Listing
February 2006

Loss of Cyclin B1 followed by downregulation of Cyclin A/Cdk2, apoptosis and antiproliferation in Hela cell line.

Int J Cancer 2005 Sep;116(4):520-5

Brain Korea 21 Project for Medical Science, Yonsei Univesity, Seoul, Korea.

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http://dx.doi.org/10.1002/ijc.21056DOI Listing
September 2005

Her2 genotype and breast cancer progression in Korean women.

Pathol Int 2005 Feb;55(2):48-52

Department of Pathology, Pochon CHA University, 351 Yatapdong Bundang-gu, Sungnam, Kyonggi-do 463-712, South Korea.

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http://dx.doi.org/10.1111/j.1440-1827.2005.01789.xDOI Listing
February 2005

Molecular characterization of uterine clear cell carcinoma.

Mod Pathol 2004 May;17(5):530-7

Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, NY 10021, USA.

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http://dx.doi.org/10.1038/modpathol.3800057DOI Listing
May 2004

IMUP-1 and IMUP-2 genes are up-regulated in human ovarian epithelial tumors.

Anticancer Res 2003 Nov-Dec;23(6C):4709-13

Graduate School of Life Science and Biotechnology, College of Medicine, Pochon CHA University, Seoul 135-081, South Korea.

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April 2004

Overexpression of cyclooxygenase-2 is associated with breast carcinoma and its poor prognostic factors.

Mod Pathol 2003 Dec;16(12):1199-204

Department of Pathology, Bundang CHA Hospital, Pochon CHA University, Sungnam, Korea.

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http://dx.doi.org/10.1097/01.MP.0000097372.73582.CBDOI Listing
December 2003

Regeneration of hepatocyte 'buds' in cirrhosis from intrabiliary stem cells.

J Hepatol 2003 Sep;39(3):357-64

Department of Pathology, Albert Einstein College of Medicine, Yeshiva University, Bronx, NY, USA.

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http://dx.doi.org/10.1016/s0168-8278(03)00309-xDOI Listing
September 2003

Expression of the DNA repair enzyme, N-methylpurine-DNA glycosylase (MPG) in astrocytic tumors.

Anticancer Res 2003 Mar-Apr;23(2B):1417-23

Department of Biochemistry, Institute for Clinical Research, College of Medicine, Pochon CHA University, Sungnam 463-712, S. Korea.

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July 2003

Altered imprinting, promoter usage, and expression of insulin-like growth factor-II gene in gestational trophoblastic diseases.

Gynecol Oncol 2003 Mar;88(3):411-8

Comprehensive Gynecologic Cancer Center, Pundang CHA General Hospital, Sungnam, Kyonggi-do, South Korea.

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http://dx.doi.org/10.1016/s0090-8258(02)00143-9DOI Listing
March 2003

Genotyping of 22 human papillomavirus types by DNA chip in Korean women: comparison with cytologic diagnosis.

Am J Obstet Gynecol 2003 Jan;188(1):56-62

Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1067/mob.2003.120DOI Listing
January 2003

Altered expression of the DNA repair protein, N-methylpurine-DNA glycosylase (MPG) in human gonads.

Anticancer Res 2002 Mar-Apr;22(2A):793-8

Department of Biochemistry and Institute for Clinical Research, College of Medicine, Pochon CHA University, Sungnam, Korea.

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June 2002