Publications by authors named "Hee-Jun Na"

29Publications

Antibody-Based Targeting of Cell Surface GRP94 Specifically Inhibits Cetuximab-Resistant Colorectal Cancer Growth.

Biomolecules 2019 11 1;9(11). Epub 2019 Nov 1.

Biopharmaceutical Chemistry Major, School of Applied Chemistry, Kookmin University, Seoul 02707, Korea.

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November 2019

TSPYL5-mediated inhibition of p53 promotes human endothelial cell function.

Angiogenesis 2019 05 23;22(2):281-293. Epub 2018 Nov 23.

Stem Cell Research Laboratory, Immunotherapy Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, 125 Gwahak-ro, Yuseong-gu, Taejon, 34141, Republic of Korea.

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May 2019

Necroptosis Is a Mechanism of Death in Mouse Induced Hepatocyte-Like Cells Reprogrammed from Mouse Embryonic Fibroblasts.

Mol Cells 2018 Jul 10;41(7):639-645. Epub 2018 Jul 10.

College of Veterinary Medicine, Kangwon National University, Chuncheon 24341, Korea.

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July 2018

A Review of Anti-Angiogenic Targets for Monoclonal Antibody Cancer Therapy.

Int J Mol Sci 2017 Aug 17;18(8). Epub 2017 Aug 17.

Research Center, Scripps Korea Antibody Institute, Chuncheon 200-701, Korea.

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August 2017

Ig-like domain 6 of VCAM-1 is a potential therapeutic target in TNFα-induced angiogenesis.

Exp Mol Med 2017 02 17;49(2):e294. Epub 2017 Feb 17.

Laboratory of Molecular Cancer Therapeutics, Research Center, Scripps Korea Antibody Institute, Chuncheon, Republic of Korea.

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February 2017

Biomarker Discovery by Modeling Behçet's Disease with Patient-Specific Human Induced Pluripotent Stem Cells.

Stem Cells Dev 2017 01 16;26(2):133-145. Epub 2016 Nov 16.

2 Department of Functional Genomics, University of Science and Technology , Daejeon, Republic of Korea.

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January 2017

Heat shock protein 70-1A is a novel angiogenic regulator.

Biochem Biophys Res Commun 2016 Jan 30;469(2):222-8. Epub 2015 Nov 30.

Scripps Korea Antibody Institute, Hyoja-2-dong, Chuncheon-si, Gangwon-do, 200-701, South Korea. Electronic address:

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January 2016

TXNIP deficiency exacerbates endotoxic shock via the induction of excessive nitric oxide synthesis.

PLoS Pathog 2013 3;9(10):e1003646. Epub 2013 Oct 3.

Immunotherapy Research Center, Korea Research Institute of Bioscience and Biotechnology, Yuseong-gu, Daejeon, Republic of Korea ; Department of Functional Genomics, University of Science and Technology, Yuseong-gu, Daejeon, Republic of Korea.

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May 2014

TRAIL negatively regulates VEGF-induced angiogenesis via caspase-8-mediated enzymatic and non-enzymatic functions.

Angiogenesis 2014 Jan 5;17(1):179-94. Epub 2013 Oct 5.

Vascular Homeostasis Laboratory and Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon, Gangwon-do, 200-701, Korea.

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January 2014

Inhibition of MKK7-JNK by the TOR signaling pathway regulator-like protein contributes to resistance of HCC cells to TRAIL-induced apoptosis.

Gastroenterology 2012 Nov 27;143(5):1341-1351. Epub 2012 Jul 27.

Medical Genomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, South Korea; Department of Functional Genomics, University of Science and Technology, Daejeon, South Korea. Electronic address:

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November 2012

Autophagy promotes intracellular degradation of type I collagen induced by transforming growth factor (TGF)-β1.

J Biol Chem 2012 Apr 20;287(15):11677-88. Epub 2012 Feb 20.

Renal Division, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

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April 2012

TGF-{beta}1 protects against mesangial cell apoptosis via induction of autophagy.

J Biol Chem 2010 Nov 28;285(48):37909-19. Epub 2010 Sep 28.

Renal Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

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November 2010

Transforming growth factor-beta (TGF-beta1) activates TAK1 via TAB1-mediated autophosphorylation, independent of TGF-beta receptor kinase activity in mesangial cells.

J Biol Chem 2009 Aug 25;284(33):22285-96. Epub 2009 Jun 25.

Renal Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

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August 2009

The non-provitamin A carotenoid, lutein, inhibits NF-kappaB-dependent gene expression through redox-based regulation of the phosphatidylinositol 3-kinase/PTEN/Akt and NF-kappaB-inducing kinase pathways: role of H(2)O(2) in NF-kappaB activation.

Free Radic Biol Med 2008 Sep 27;45(6):885-96. Epub 2008 Jun 27.

Vascular System Research Center and Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chunchon, Kangwon-do 200-701, Korea.

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September 2008

CT20126, a novel immunosuppressant, prevents collagen-induced arthritis through the down-regulation of inflammatory gene expression by inhibiting NF-kappaB activation.

Biochem Pharmacol 2008 Jul 18;76(1):79-90. Epub 2008 Apr 18.

Department of Molecular and Cellular Biochemistry and Vascular System Research Center, School of Medicine, Kangwon National University, Chunchon, Kangwon-Do 200-701, Republic of Korea.

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July 2008

4-O-methylgallic acid down-regulates endothelial adhesion molecule expression by inhibiting NF-kappaB-DNA-binding activity.

Eur J Pharmacol 2006 Dec 8;551(1-3):143-51. Epub 2006 Sep 8.

Vascular System Research Center, School of Medicine, Kangwon National University, Chunchon, 200-701, Republic of Korea.

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December 2006

4-O-Methylgallic acid suppresses inflammation-associated gene expression by inhibition of redox-based NF-kappaB activation.

Int Immunopharmacol 2006 Oct 7;6(10):1597-608. Epub 2006 Jul 7.

Vascular System Research Center and Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chunchon 200-701, Republic of Korea.

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October 2006

beta-Carotene inhibits inflammatory gene expression in lipopolysaccharide-stimulated macrophages by suppressing redox-based NF-kappaB activation.

Exp Mol Med 2005 Aug;37(4):323-34

Vascular System Research Center, Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chunchon, Kangwon-do 200-701, Korea.

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August 2005

Antiangiogenic activity of 4-O-methylgallic acid from Canavalia gladiata, a dietary legume.

Biochem Biophys Res Commun 2005 May;330(4):1268-74

Chemical Genomics National Research Laboratory, Department of Bioscience and Biotechnology, Institute of Bioscience, Sejong University, Kwangjin-Gu, Seoul 143-747, Republic of Korea.

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May 2005