Publications by authors named "Hee Sun Byun"

34Publications

3-O-acetylrubianol C (3AR-C) induces RIPK1-dependent programmed cell death by selective inhibition of IKKβ.

Authors:
Kidong Kang Khong Trong Quan Hee Sun Byun So-Ra Lee Xuezhe Piao Eunjin Ju Kyeong Ah Park Kyung-Cheol Sohn Han-Ming Shen MinKyun Na Gang Min Hur

FASEB J 2020 03 6;34(3):4369-4383. Epub 2020 Feb 6.

Department of Pharmacology and Department of Medical Science, College of Medicine, Chungnam National University, Daejeon, Republic of Korea.

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March 2020

Accelerated degradation of cFLIP and sensitization of the TRAIL DISC-mediated apoptotic cascade by pinoresinol, a lignan isolated from Rubia philippinensis.

Authors:
So-Ra Lee Khong Trong Quan Hee Sun Byun InWha Park Kidong Kang Xuezhe Piao Eunjin Ju Hyunju Ro MinKyun Na Gang Min Hur

Sci Rep 2019 09 18;9(1):13505. Epub 2019 Sep 18.

Department of Pharmacology and Department of Medical Science, College of Medicine, Chungnam National University, 266 Munhwa-ro, Daejeon, 35015, Republic of Korea.

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September 2019

Oridonin enhances TRAIL-induced apoptosis through GALNT14-mediated DR5 glycosylation.

Authors:
Mi-Yeon Jeon Seung Un Seo Seon Min Woo Kyoung-Jin Min Hee Sun Byun Gang Min Hur Sun Chul Kang Taeg Kyu Kwon

Biochimie 2019 Oct 20;165:108-114. Epub 2019 Jul 20.

Department of Immunology, School of Medicine, Keimyung University, 1095 Dalgubeoldaero, Dalseo-Gu, Daegu, 42601, South Korea. Electronic address:

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October 2019

C-27-carboxylated oleanane triterpenoids up-regulate TRAIL DISC assembly via p38 MAPK and CHOP-mediated DR5 expression in human glioblastoma cells.

Authors:
Hee Sun Byun Wei Zhou InWha Park Kidong Kang So-Ra Lee Xuezhe Piao Jin Bong Park Taeg Kyu Kwon MinKyun Na Gang Min Hur

Biochem Pharmacol 2018 12 22;158:243-260. Epub 2018 Oct 22.

Department of Pharmacology, College of Medicine, Chungnam National University, 266 Munhwa-ro, Daejeon 35015, Republic of Korea. Electronic address:

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December 2018

The anti-inflammatory role of extranuclear apurinic/apyrimidinic endonuclease 1/redox effector factor-1 in reactive astrocytes.

Authors:
Hyunjung Baek Chae Seong Lim Hee Sun Byun Hyun Sil Cho Yu Ran Lee Yong Sup Shin Hyun-Woo Kim Byeong Hwa Jeon Dong Woon Kim Jinpyo Hong Gang Min Hur Jin Bong Park

Mol Brain 2016 12 16;9(1):99. Epub 2016 Dec 16.

Department of Physiology and Department of Medical Science, School of Medicine, Chungnam National University, 266 Munhwa-Ro, Jung-gu, Daejeon, 30501, Republic of Korea.

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December 2016

IinQ attenuates systemic inflammatory responses via selectively impairing the Myddosome complex formation upon TLR4 ligation.

Authors:
Kidong Kang Minho Won Jae-Min Yuk Chan-Yong Park Hee Sun Byun Kyeong Ah Park So-Ra Lee Young-Goo Kang Han-Ming Shen Ill Young Lee Gang Min Hur

Biochem Pharmacol 2016 Dec 21;121:52-66. Epub 2016 Sep 21.

Department of Pharmacology, College of Medicine, Chungnam National University, 266 Munhwa-ro, Daejeon 35015, Republic of Korea; Department of Medical Science, College of Medicine, Chungnam National University, 266 Munhwa-ro, Daejeon 35015, Republic of Korea. Electronic address:

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December 2016

Post-translational control of NF-κB signaling by ubiquitination.

Authors:
Minho Won Hee Sun Byun Kyeong Ah Park Gang Min Hur

Arch Pharm Res 2016 Aug 10;39(8):1075-84. Epub 2016 Jun 10.

Research Institute for Medical Science, College of Medicine, Chungnam National University, Daejeon, 35015, Republic of Korea.

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August 2016

Terminalia Chebula provides protection against dual modes of necroptotic and apoptotic cell death upon death receptor ligation.

Authors:
Yoonjung Lee Hee Sun Byun Jeong Ho Seok Kyeong Ah Park Minho Won Wonhyoung Seo So-Ra Lee Kidong Kang Kyung-Cheol Sohn Ill Young Lee Hyeong-Geug Kim Chang Gue Son Han-Ming Shen Gang Min Hur

Sci Rep 2016 04 27;6:25094. Epub 2016 Apr 27.

Department of Pharmacology, Research Institute for Medical Science, College of Medicine, Chungnam National University, Daejeon 301-131, Republic of Korea.

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April 2016

Brazilin Limits Inflammatory Responses through Induction of Prosurvival Autophagy in Rheumatoid Fibroblast-Like Synoviocytes.

Authors:
Hyunji Lee Seong Wook Kang Hee Sun Byun Juhee Jeon Kyeong Ah Park Kidong Kang Wonhyoung Seo Minho Won Jeong Ho Seok Man-Deuk Han Han-Ming Shen Gang Min Hur

PLoS One 2015 21;10(8):e0136122. Epub 2015 Aug 21.

Department of Pharmacology, College of Medicine, Chungnam National University, Daejeon, Republic of Korea.

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May 2016

Casein kinase II regulates N-methyl-D-aspartate receptor activity in spinal cords and pain hypersensitivity induced by nerve injury.

Authors:
Shao-Rui Chen Hong-Yi Zhou Hee Sun Byun Hong Chen Hui-Lin Pan

J Pharmacol Exp Ther 2014 Aug 4;350(2):301-12. Epub 2014 Jun 4.

Center for Neuroscience and Pain Research, Department of Anesthesiology and Perioperative Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas

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August 2014

Brazilin selectively disrupts proximal IL-1 receptor signaling complex formation by targeting an IKK-upstream signaling components.

Authors:
Juhee Jeon Ji Hoon Lee Kyeong Ah Park Hee Sun Byun Hyunji Lee Yoonjung Lee Tiejun Zhang Kidong Kang Jeong Ho Seok Hyun-Jung Kwon Man-Deuk Han Seong Wook Kang Jang Hee Hong Gang Min Hur

Biochem Pharmacol 2014 Jun 13;89(4):515-25. Epub 2014 Apr 13.

Department of Pharmacology, Daejeon Regional Cancer Center, College of Medicine, Chungnam National University, 6 Munhwa-dong, Jung-gu, Daejeon 301-747, Republic of Korea. Electronic address:

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June 2014

Nerve injury increases GluA2-lacking AMPA receptor prevalence in spinal cords: functional significance and signaling mechanisms.

Authors:
Shao-Rui Chen Hong-Yi Zhou Hee Sun Byun Hui-Lin Pan

J Pharmacol Exp Ther 2013 Dec 12;347(3):765-72. Epub 2013 Sep 12.

Center for Neuroscience and Pain Research, Department of Anesthesiology and Perioperative Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, Texas (S.-R.C., H.-Y.Z., H.S.B., H.-L.P.); Graduate Program in Neuroscience, The University of Texas Graduate School of Biomedical Sciences, Houston, Texas (H.-L.P.).

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December 2013

PHF20 regulates NF-κB signalling by disrupting recruitment of PP2A to p65.

Authors:
Tiejun Zhang Kyeong Ah Park Yuwen Li Hee Sun Byun Juhee Jeon Yoonjung Lee Jang Hee Hong Jin Man Kim Song-Mei Huang Seung-Won Choi Seon-Hwan Kim Kyung-Cheol Sohn Hyunju Ro Ji Hoon Lee Tao Lu George R Stark Han-Ming Shen Zheng-Gang Liu Jongsun Park Gang Min Hur

Nat Commun 2013 ;4:2062

Department of Pharmacology, Infection Signaling Network Research Center, College of Medicine, Chungnam National University, Daejeon 301 747, South Korea.

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December 2013

Intron-derived aberrant splicing of A20 transcript in rheumatoid arthritis.

Authors:
Hyun Kyung Yoon Hee Sun Byun Hyunji Lee Juhee Jeon Yoonjung Lee Yuwen Li Eun-Heui Jin JaeWoo Kim Jang Hee Hong Jin Hyun Kim Jeong Ho Seok Seong Wook Kang Won Hyung Lee Gang Min Hur

Rheumatology (Oxford) 2013 Mar 12;52(3):427-37. Epub 2012 Nov 12.

Department of Pharmacology, College of Medicine, Chungnam National University, 6 Munhwa-dong, Jung-gu, Daejeon, Korea.

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March 2013

N-methyl-D-aspartate receptor- and calpain-mediated proteolytic cleavage of K+-Cl- cotransporter-2 impairs spinal chloride homeostasis in neuropathic pain.

Authors:
Hong-Yi Zhou Shao-Rui Chen Hee-Sun Byun Hong Chen Li Li Hee-Dong Han Gabriel Lopez-Berestein Anil K Sood Hui-Lin Pan

J Biol Chem 2012 Sep 1;287(40):33853-64. Epub 2012 Aug 1.

Center for Neuroscience and Pain Research, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

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September 2012

NKCC1 upregulation disrupts chloride homeostasis in the hypothalamus and increases neuronal activity-sympathetic drive in hypertension.

Authors:
Zeng-You Ye De-Pei Li Hee Sun Byun Li Li Hui-Lin Pan

J Neurosci 2012 Jun;32(25):8560-8

Center for Neuroscience and Pain Research, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

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June 2012

Cucurbitacin induces autophagy through mitochondrial ROS production which counteracts to limit caspase-dependent apoptosis.

Authors:
Tiejun Zhang Yuwen Li Kyeong Ah Park Hee Sun Byun Minho Won Juhee Jeon Yoonjung Lee Jeong Ho Seok Seung-Won Choi Sang-Hee Lee Jin Man Kim Ji Hoon Lee Chang Gue Son Zee-Won Lee Han-Ming Shen Gang Min Hur

Autophagy 2012 Apr 1;8(4):559-76. Epub 2012 Apr 1.

Department of Pharmacology, Research Institute for Medical Science, Infection Signaling Network Research Center, Daejeon Regional Cancer Center, Daejeon, Republic of Korea.

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April 2012

Diabetic neuropathy enhances voltage-activated Ca2+ channel activity and its control by M4 muscarinic receptors in primary sensory neurons.

Authors:
Xue-Hong Cao Hee Sun Byun Shao-Rui Chen Hui-Lin Pan

J Neurochem 2011 Nov 21;119(3):594-603. Epub 2011 Sep 21.

Department of Anesthesiology and Perioperative Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

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November 2011

Apoptosis signal-regulating kinase1 is inducible by protein kinase Cδ and contributes to phorbol ester-mediated G1 phase arrest through persistent JNK activation.

Authors:
Young-Rae Kim Hee Sun Byun Juhee Jeon Byung Lyul Choi Kyeong Ah Park Minho Won Tiejun Zhang Sanghee Shin Hyunji Lee Junseo Oh Gang Min Hur

Cell Biochem Biophys 2011 Sep;61(1):199-207

Department of Pharmacology, Research Institute for Medical Science, Infection Signaling Network Research Center, Daejeon Regional Cancer Center, College of Medicine, Chungnam National University, Daejeon 301-131, Republic of Korea.

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September 2011

Reduction in voltage-gated K+ channel activity in primary sensory neurons in painful diabetic neuropathy: role of brain-derived neurotrophic factor.

Authors:
Xue-Hong Cao Hee-Sun Byun Shao-Rui Chen You-Qing Cai Hui-Lin Pan

J Neurochem 2010 Sep 24;114(5):1460-75. Epub 2010 Jun 24.

Department of Anesthesiology and Perioperative Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

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September 2010

Heat shock protein 70-mediated sensitization of cells to apoptosis by Carboxyl-Terminal Modulator Protein.

Authors:
Longzhen Piao Yuwen Li Keum-Jin Yang Kyeong Ah Park Hee Sun Byun Minho Won Janghee Hong Jeong-Lan Kim Gi Ryang Kweon Gang Min Hur Jeong Ho Seok Jae Youl Cho Taehoon Chun Daniel Hess Ragna Sack Sauveur-Michel Maira Derek P Brazil Brian A Hemmings Jongsun Park

BMC Cell Biol 2009 Jul 15;10:53. Epub 2009 Jul 15.

Department of Pharmacology, Daejeon Regional Cancer Center, Cancer Research Institute, Research Institute for Medical Sciences, College of Medicine, Chungnam National University, Taejeon, 301-131, Korea.

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July 2009

Protein kinase SGK1 enhances MEK/ERK complex formation through the phosphorylation of ERK2: implication for the positive regulatory role of SGK1 on the ERK function during liver regeneration.

Authors:
Minho Won Kyeong Ah Park Hee Sun Byun Young-Rae Kim Byung Lyul Choi Jang Hee Hong Jongsun Park Jeong Ho Seok Young-Ho Lee Chung-Hyun Cho In Sang Song Yong Kyung Kim Han-Ming Shen Gang Min Hur

J Hepatol 2009 Jul 16;51(1):67-76. Epub 2009 Apr 16.

Department of Pharmacology, Research Institute for Medical Science, Infection Signaling Network Research Center, Daejeon Regional Cancer Center, College of Medicine, Chungnam National University, 6 Munhwa-dong, Jung-gu, Daejeon 301-131, Republic of Korea.

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July 2009

Association of LETM1 and MRPL36 contributes to the regulation of mitochondrial ATP production and necrotic cell death.

Authors:
Longzhen Piao Yuwen Li Soung Jung Kim Hee Sun Byun Song Mei Huang Soon-Kyung Hwang Keum-Jin Yang Kyeong Ah Park Minho Won Janghee Hong Gang Min Hur Jeong Ho Seok Minho Shong Myung-Haing Cho Derek P Brazil Brian A Hemmings Jongsun Park

Cancer Res 2009 Apr 24;69(8):3397-404. Epub 2009 Mar 24.

Department of Pharmacology, Daejeon Regional Cancer Center, Cancer Research Institute, Research Institute for Medical Sciences, South Korea.

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April 2009

Regulation of OPA1-mediated mitochondrial fusion by leucine zipper/EF-hand-containing transmembrane protein-1 plays a role in apoptosis.

Authors:
Longzhen Piao Yuwen Li Soung Jung Kim Kyung-Cheol Sohn Keum-Jin Yang Kyeong Ah Park Hee Sun Byun Minho Won Janghee Hong Gang Min Hur Jeong Ho Seok Minho Shong Ragna Sack Derek P Brazil Brian A Hemmings Jongsun Park

Cell Signal 2009 May 9;21(5):767-77. Epub 2009 Jan 9.

Department of Pharmacology, Daejeon Regional Cancer Center, Cancer Research Institute, Research Institute for Medical Sciences, College of Medicine, Chungnam National University, Taejeon, 301-131, Republic of Korea.

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May 2009

Activation Mechanism of Protein Kinase B by DNA-dependent Protein Kinase Involved in the DNA Repair System.

Authors:
Yuwen Li Longzhen Piao Keum-Jin Yang Sanghee Shin Eulsoon Shin Kyung Ah Park Hee Sun Byun Minho Won Byung Lyul Choi Hyunji Lee Young-Rae Kim Jang Hee Hong Gang Min Hur Jeong-Lan Kim Jae Youl Cho Jeong Ho Seok Jongsun Park

Toxicol Res 2008 Sep 1;24(3):175-182. Epub 2008 Sep 1.

13Department of Pharmacology, Cell Signaling Laboratory, Research Center for Transgenic Cloned Pigs, Daejeon Regional Cancer Center, Cancer Research Institute, Research Institute for Medical Sciences, Korea.

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September 2008

Long-term Activation of c-Jun N-terminal Kinase through Receptor Interacting Protein is Associated with DNA Damage-induced Cell Death.

Authors:
Jeong Ho Seok Kyeong Ah Park Hee Sun Byun Minho Won Sanghee Shin Byung-Lyul Choi Hyunji Lee Young-Rae Kim Jang Hee Hong Jongsun Park Gang Min Hur

Korean J Physiol Pharmacol 2008 Aug 31;12(4):185-91. Epub 2008 Aug 31.

Department of Pharmacology, Research Institute for Medical Sciences, College of Medicine, Chungnam National University, Daejeon 301-131, Korea.

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August 2008

Modulatory role of phospholipase D in the activation of signal transducer and activator of transcription (STAT)-3 by thyroid oncogenic kinase RET/PTC.

Authors:
Young-Rae Kim Hee Sun Byun Minho Won Kyeong Ah Park Jin Man Kim Byung Lyul Choi Hyunji Lee Jang Hee Hong Jongsun Park Jeong Ho Seok Dong Wook Kim Minho Shong Seung-Kiel Park Gang Min Hur

BMC Cancer 2008 May 23;8:144. Epub 2008 May 23.

Department of Pharmacology, College of Medicine, Chungnam National University, Daejeon, 301-131, South Korea.

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May 2008

Prevention of TNF-induced necrotic cell death by rottlerin through a Nox1 NADPH oxidase.

Authors:
Hee Sun Byun Minho Won Kyeong Ah Park Young-Rae Kim Byung Lyul Choi Hyunji Lee Jang Hee Hong Longzhen Piao Jongsun Park Jin Man Kim Gi Ryang Kweon Sung Hyun Kang Jin Han Gang Min Hur

Exp Mol Med 2008 Apr;40(2):186-95

Department of Pharmacology, Research Institute for Medical Science, Infection Signaling Network Research Center, College of Medicine, Chungnam National University, Daejeon 301-131, Korea.

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April 2008

Cyclo(dehydrohistidyl-l-tryptophyl) inhibits nitric oxide production by preventing the dimerization of inducible nitric oxide synthase.

Authors:
Mi-Jin Sohn Gang-Min Hur Hee-Sun Byun Won-Gon Kim

Biochem Pharmacol 2008 Feb 24;75(4):923-30. Epub 2007 Oct 24.

Functional Metabolites Research Center, Korea Research Institute of Bioscience and Biotechnology, Yusong, Daejeon 305-806, Republic of Korea.

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February 2008

Regulation of 3-phosphoinositide-dependent protein kinase-1 (PDK1) by Src involves tyrosine phosphorylation of PDK1 and Src homology 2 domain binding.

Authors:
Keum-Jin Yang Sanghee Shin Longzhen Piao Eulsoon Shin Yuwen Li Kyeong Ah Park Hee Sun Byun Minho Won Janghee Hong Gi Ryang Kweon Gang Min Hur Jeong Ho Seok Taehoon Chun Derek P Brazil Brian A Hemmings Jongsun Park

J Biol Chem 2008 Jan 16;283(3):1480-91. Epub 2007 Nov 16.

Department of Pharmacology, Daejeon Regional Cancer Center, Cancer Research Institute, Chungnam National University, 6 Munhwa-Dong, Jung-Gu, Taejeon 301-131, South Korea.

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January 2008

Phorbol 12-myristate 13-acetate protects against tumor necrosis factor (TNF)-induced necrotic cell death by modulating the recruitment of TNF receptor 1-associated death domain and receptor-interacting protein into the TNF receptor 1 signaling complex: Implication for the regulatory role of protein kinase C.

Authors:
Hee Sun Byun Kyeong Ah Park Minho Won Keum-Jin Yang Sanghee Shin Longzhen Piao Jin Young Kwak Zee-Won Lee Jongsun Park Jeong Ho Seok Zheng-Gang Liu Gang Min Hur

Mol Pharmacol 2006 Sep 23;70(3):1099-108. Epub 2006 Jun 23.

Department of Pharmacology, College of Medicine, Chungnam National University, 6 Munhwa-dong, Jung-gu, Daejeon 301-131, Korea.

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September 2006

Sustained activation of protein kinase C downregulates nuclear factor-kappaB signaling by dissociation of IKK-gamma and Hsp90 complex in human colonic epithelial cells.

Authors:
Kyeong Ah Park Hee Sun Byun Minho Won Keum-Jin Yang Sanghee Shin Longzhen Piao Jin Man Kim Wan-Hee Yoon Eunsung Junn Jongsun Park Jeong Ho Seok Gang Min Hur

Carcinogenesis 2007 Jan 14;28(1):71-80. Epub 2006 Jun 14.

Department of Pharmacology, Cancer Research Institute, College of Medicine, Chungnam National University, 6 Munhwa-dong, Jung-gu, Daejeon 301-131, Korea.

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January 2007

Thioredoxin overexpression in HT-1080 cells induced cellular senescence and sensitization to gamma radiation.

Authors:
Hee Sun Byun Eun Wie Cho Jin Sik Kim Myung Sook Moon Jung Joo Yum Kug Chan Kim In Gyu Kim

FEBS Lett 2005 Aug;579(19):4055-62

Department of Radiation Biology, Environmental Radiation Research Group, Korea Atomic Energy Research Institute, P.O. Box 105, Yuseong, Daejeon 305-600, Republic of Korea.

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August 2005

GAD 67KD antisense in colon cancer cells inhibits cell growth and sensitizes to butyrate and pH reduction and H2O2 and gamma-radiation.

Authors:
Myung Sook Moon Eun Wie Cho Hee Sun Byun Il Lae Jung In Gyu Kim

Arch Biochem Biophys 2004 Oct;430(2):229-36

Department of Radiation Biology, Environmental Radiation Research Group, Korea Atomic Energy Research Institute, PO Box 105, Yusong, Taejon 305-600, Republic of Korea.

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October 2004