Publications by authors named "Hedy L Kindler"

100Publications

Heterogeneity in PD-L1 expression in malignant peritoneal mesothelioma with systemic or intraperitoneal chemotherapy.

Br J Cancer 2020 Oct 26. Epub 2020 Oct 26.

Department of Surgery, Section of General Surgery and Surgical Oncology, University of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1038/s41416-020-01130-xDOI Listing
October 2020

Maintenance Olaparib for Metastatic Pancreatic Cancer. Reply.

N Engl J Med 2019 10;381(15):1492-1493

University of Chicago, Chicago, IL.

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http://dx.doi.org/10.1056/NEJMc1911185DOI Listing
October 2019

Maintenance Olaparib for Germline -Mutated Metastatic Pancreatic Cancer.

N Engl J Med 2019 07 2;381(4):317-327. Epub 2019 Jun 2.

From the Oncology Institute, Sheba Medical Center, Tel Aviv University, Tel Aviv, Israel (T.G.); Hôpital Beaujon (Assistance Publique-Hôpitaux de Paris), Clichy, and University Paris VII, Paris (P.H.); IRCCS Ospedale San Raffaele Scientific Institute, Milan (M.R.), Azienda Ospedaliera Universitaria Integrata Verona, Verona (G.T.), and Fondazione Policlinico Universitario Gemelli IRCCS, Rome (G.T.) - all in Italy; University Hospitals Gasthuisberg and KU Leuven, Leuven, Belgium (E.V.C.); Vall d'Hebron University Hospital and Vall d'Hebron Institute of Oncology, Barcelona (T.M.); Fox Chase Cancer Center, Philadelphia (M.J.H.); Samsung Medical Center, Sungkyunkwan University School of Medicine (J.-O.P.), and Seoul National University Hospital, Cancer Research Institute, Seoul National University College of Medicine (D.-Y.O.) - both in Seoul, South Korea; University College London Cancer Institute, London (D.H.), and AstraZeneca, Cambridge (D.M.) - both in the United Kingdom; Asklepios Tumorzentrum Hamburg Asklepios Klinik Altona, Hamburg (D.A.), St. Josef-Hospital, Ruhr University Bochum, Bochum (A.R.-S.), and Klinikum rechts der Isar, Department of Internal Medicine II, Technische Universität München, Munich (H.A.) - all in Germany; Memorial Sloan Kettering Cancer Center, New York (E.M.O.); AstraZeneca, Gaithersburg, MD (K.Y.C., G.Y.L.); Merck, Kenilworth, NJ (K.S.); and the University of Chicago, Chicago (H.L.K.).

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http://dx.doi.org/10.1056/NEJMoa1903387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810605PMC
July 2019

A Glimmer of Hope for Pancreatic Cancer.

Authors:
Hedy L Kindler

N Engl J Med 2018 12;379(25):2463-2464

From the Section of Hematology-Oncology, University of Chicago Medicine, Chicago.

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http://dx.doi.org/10.1056/NEJMe1813684DOI Listing
December 2018

Frequency of Germline Mutations in Cancer Susceptibility Genes in Malignant Mesothelioma.

J Clin Oncol 2018 10 16;36(28):2863-2871. Epub 2018 Aug 16.

Vasiliki Panou and Oluf D. Røe, Aalborg University Hospital, Aalborg, Denmark; Meghana Gadiraju, Arthur Wolin, Caroline M. Weipert, Emily Skarda, Aliya N. Husain, Jyoti D. Patel, Buerkley Rose, Shannon R. Zhang, Madison Weatherly, Viswateja Nelakuditi, Amy Knight Johnson, Maria Helgeson, David Fischer, Arpita Desai, Nanna Sulai, Lauren Ritterhouse, Kiran K. Turaga, Dezheng Huo, Jeremy Segal, Sabah Kadri, Zejuan Li, Hedy L. Kindler, and Jane E. Churpek, The University of Chicago, Chicago, IL; Oluf D. Røe, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger; and Oluf D. Røe, Norwegian University of Science and Technology, Trondheim, Norway.

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http://ascopubs.org/doi/10.1200/JCO.2018.78.5204
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http://dx.doi.org/10.1200/JCO.2018.78.5204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804864PMC
October 2018

Dynamic contrast-enhanced CT for the assessment of tumour response in malignant pleural mesothelioma: a pilot study.

Eur Radiol 2019 Feb 2;29(2):682-688. Epub 2018 Jul 2.

Department of Radiology, The University of Chicago, 5841 South Maryland Avenue, Chicago, IL, 60637, USA.

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http://dx.doi.org/10.1007/s00330-018-5533-9DOI Listing
February 2019

Reply to D. de Fonseka et al.

J Clin Oncol 2018 09 14;36(26):2746-2747. Epub 2018 Jun 14.

Hedy L. Kindler, The University of Chicago, Chicago, IL; Valerie Rusch, Memorial Sloan Kettering Cancer Center, New York NY; Raphael Bueno, Harvard Medical School, Boston, MA; Nofisat Ismaila, American Society of Clinical Oncology, Alexandria VA; Harvey Pass and Daniel Sterman, New York University Langone Medical Center, New York, NY; and Raffit Hassan, National Cancer Institute, Bethesda, MD.

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http://dx.doi.org/10.1200/JCO.2018.78.7333DOI Listing
September 2018

The impact of changes in radiographic sarcopenia on overall survival in older adults undergoing different treatment pathways for pancreatic cancer.

J Geriatr Oncol 2018 07 10;9(4):367-372. Epub 2018 Mar 10.

Department of Supportive Care Medicine, City of Hope, Duarte, CA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jgo.2018.03.002DOI Listing
July 2018

Treatment of Malignant Pleural Mesothelioma: American Society of Clinical Oncology Clinical Practice Guideline Summary.

J Oncol Pract 2018 04 8;14(4):256-264. Epub 2018 Mar 8.

The University of Chicago, Chicago, IL; American Society of Clinical Oncology, Alexandria VA; and National Cancer Institute, Bethesda, MD.

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http://dx.doi.org/10.1200/JOP.17.00012DOI Listing
April 2018

Nut Consumption and Survival in Patients With Stage III Colon Cancer: Results From CALGB 89803 (Alliance).

J Clin Oncol 2018 04 28;36(11):1112-1120. Epub 2018 Feb 28.

Temidayo Fadelu, Sui Zhang, Robert J. Mayer, Shuji Ogino, Kimmie Ng, Jeffrey Meyerhardt, and Charles S. Fuchs, Dana-Farber/Partners CancerCare; Shuji Ogino, Kana Wu, Walter Willett, and Edward Giovannucci, Harvard TH Chan School of Public Health; Shuji Ogino, Edward Giovannucci, and Ying Bao, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA; Donna Niedzwiecki and Xing Ye, Alliance Statistics and Data Center, Duke University, Durham; Michael Messino, Southeast Clinical Oncology Research Consortium, Mission Hospitals, Asheville, NC; Leonard B. Saltz, Memorial Sloan Kettering Cancer Center, New York, NY; Rex B. Mowat, Toledo Community Hospital Oncology Program, Toledo, OH; Renaud Whittom, Hôpital du Sacré-Coeur de Montréal, Montreal, Quebec, Canada; Alexander Hantel, Loyola University Stritch School of Medicine, Naperville; Al B. Benson, Robert H Lurie Comprehensive Cancer Center, Northwestern University; Hedy L. Kindler, University of Chicago Comprehensive Cancer, Chicago, IL; Daniel M. Atienza, Virginia Oncology Associates, Norfolk, VA; Alan Venook, University of California at San Francisco Comprehensive Cancer Center, San Francisco, CA; and Charles S. Fuchs, Yale Cancer Center, Yale School of Medicine, New Haven, CT.

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http://dx.doi.org/10.1200/JCO.2017.75.5413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891130PMC
April 2018

Treatment of Malignant Pleural Mesothelioma: American Society of Clinical Oncology Clinical Practice Guideline.

J Clin Oncol 2018 05 18;36(13):1343-1373. Epub 2018 Jan 18.

Hedy L. Kindler and Samuel G. Armato III, The University of Chicago, Chicago, IL; Nofisat Ismaila, American Society of Clinical Oncology; Mary Hesdorffer, Mesothelioma Applied Research Foundation, Alexandria, VA; Raphael Bueno, Harvard Medical School, Boston, MA; Thierry Jahan, University of California San Francisco, San Francisco, CA; Clyde Michael Jones, Baptist Cancer Center Physicians Foundation, Memphis, TN; Markku Miettinen, Anish Thomas and Raffit Hassan, Center for Cancer Research, National Cancer Institute, Bethesda, MD; Harvey Pass and Daniel Sterman, New York University Langone Medical Center; and Andreas Rimner and Valerie Rusch, Memorial Sloan Kettering Cancer Center, New York, NY.

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http://ascopubs.org/doi/10.1200/JCO.2017.76.6394
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http://dx.doi.org/10.1200/JCO.2017.76.6394DOI Listing
May 2018

Amount of Epithelioid Differentiation Is a Predictor of Survival in Malignant Pleural Mesothelioma.

Ann Thorac Surg 2017 Mar 17;103(3):962-966. Epub 2016 Oct 17.

Department of Pathology, University of Chicago Medicine, Chicago, Illinois.

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http://dx.doi.org/10.1016/j.athoracsur.2016.08.063DOI Listing
March 2017

PI3 Kinase Pathway and MET Inhibition is Efficacious in Malignant Pleural Mesothelioma.

Sci Rep 2016 09 13;6:32992. Epub 2016 Sep 13.

Department of Hematology/Oncology, University of Chicago Medical Center, Chicago, IL, USA.

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http://dx.doi.org/10.1038/srep32992DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021085PMC
September 2016

Specimen weight and volume: important predictors of survival in malignant pleural mesothelioma.

Eur J Cardiothorac Surg 2016 Jun 21;49(6):1642-7. Epub 2016 Jan 21.

Section of Cardiac and Thoracic Surgery, Department of Surgery, University of Chicago, Chicago, IL, USA

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http://dx.doi.org/10.1093/ejcts/ezv422DOI Listing
June 2016

Randomized Phase Ib/II Study of Gemcitabine Plus Placebo or Vismodegib, a Hedgehog Pathway Inhibitor, in Patients With Metastatic Pancreatic Cancer.

J Clin Oncol 2015 Dec 2;33(36):4284-92. Epub 2015 Nov 2.

Daniel V.T. Catenacci, Theodore Karrison, James Wallace, Mark Kozloff, Peng Xu, Les Henderson, Ravi Salgia, Walter M. Stadler, Hedy L. Kindler, University of Chicago Medical Center; Patrick Stiff, Loyola University Medical Center, Chicago; Robert Marsh, Northshore University Health System, Evanston; James Wallace, Mark Kozloff, Ingalls Hospital, Harvey; James Wade, Decatur Memorial Hospital, Decatur; Pankaj Kumar, Oncology/Hematology Associates, Peoria, IL; Melissa R. Junttila, Xi Wang, and Frederic J. de Sauvage, Genentech, South San Francisco; Heinz-Josef Lenz, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA; Nathan Bahary, University of Pittsburgh Cancer Institute, Pittsburgh, PA; Margit N. Horiba, University of Maryland Greenebaum Cancer Center, Baltimore, MD; Sreenivasa R. Nattam, Ft Wayne Medical Oncology/Hematology, Ft Wayne, IN; Lakshmi Rajdev, Montefiore Medical Center, Bronx; Deirdre Cohen, New York University Cancer Center, New York, NY; Bethany Sleckman, St John's Mercy Medical Center, St Louis, MO; and Naoko Takebe, National Cancer Institute, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1200/JCO.2015.62.8719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678179PMC
December 2015

A Phase I Study of FOLFIRINOX Plus IPI-926, a Hedgehog Pathway Inhibitor, for Advanced Pancreatic Adenocarcinoma.

Pancreas 2016 Mar;45(3):370-5

From the *Division of Hematology/Oncology, University of California San Francisco, San Francisco, CA; †Division of Hematology/Oncology, University of Wisconsin, Madison, WI; ‡Department of Radiology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan; and §Department of Radiology and ∥Division of Hematology/Oncology, University of Chicago, Chicago, IL.

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http://dx.doi.org/10.1097/MPA.0000000000000458DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908466PMC
March 2016

Extended Pleurectomy and Decortication for Malignant Pleural Mesothelioma Is an Effective and Safe Cytoreductive Surgery in the Elderly.

Ann Thorac Surg 2015 Nov 25;100(5):1868-74. Epub 2015 Aug 25.

Department of Surgery, Section of Cardiac and Thoracic Surgery, University of Chicago Medicine, Chicago, Illinois. Electronic address:

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http://dx.doi.org/10.1016/j.athoracsur.2015.04.151DOI Listing
November 2015

Radiologic-pathologic correlation of mesothelioma tumor volume.

Lung Cancer 2015 Mar 20;87(3):278-82. Epub 2015 Jan 20.

Department of Surgery, The University of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1016/j.lungcan.2014.11.019DOI Listing
March 2015

Generalizability of trial results to elderly Medicare patients with advanced solid tumors (Alliance 70802).

J Natl Cancer Inst 2015 Jan 27;107(1):336. Epub 2014 Nov 27.

Massachusetts General Hospital Cancer Center, Boston, MA (EL); Departments of Medicine, and Health Care Policy, Harvard Medical School, Boston, MA (EL, YH, AM); American Society of Clinical Oncology, Alexandria, VA (RLS); Department of Medicine, University of North Carolina, Chapel Hill, NC (HM); Department of Medicine, Duke University, Durham, NC (HJC); City of Hope, Duarte, CA (AH); Department of Medicine, University of Chicago, Chicago, IL (HLK); Department of Medicine, University of California San Francisco, San Francisco, CA (AV); Yale Cancer Center, New Haven, CT (RL); Department of Medicine, the University of Tennessee, Memphis, TN (HN); Department of Medicine, Ohio State University, Columbus, OH (RMG); Department of Medical Ethics and Health Policy, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA (SJ).

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http://dx.doi.org/10.1093/jnci/dju336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271075PMC
January 2015

25-Hydroxyvitamin D levels and survival in advanced pancreatic cancer: findings from CALGB 80303 (Alliance).

J Natl Cancer Inst 2014 Aug 6;106(8). Epub 2014 Aug 6.

Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA (KVL, APV); Department of Biostatistics and Bioinformatics, Duke University, Durham, NC (KO, DN); Alliance Statistics and Data Center, Duke University, Durham, NC (KO, CJ, DN); The University of Chicago Medical Center, Chicago, IL (HLK); Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL (MFM); Memorial Sloan-Kettering Cancer Center, New York, NY (EMO); Dana-Farber Cancer Institute, Boston, MA (CF); University of North Carolina Institute for Pharmacogenomics and Individualized Therapy, Eshelman School of Pharmacy, School of Medicine, Lineberger Comprehensive Cancer Center, Chapel Hill, NC (FI).

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http://dx.doi.org/10.1093/jnci/dju185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155431PMC
August 2014

Considering the role of radiation therapy for gastrointestinal stromal tumor.

Onco Targets Ther 2014 12;7:713-8. Epub 2014 May 12.

Department of Radiation and Cellular Oncology, University of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.2147/OTT.S36873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026585PMC
May 2014

The Vulnerable Elders Survey-13 predicts mortality in older adults with later-stage colorectal cancer receiving chemotherapy: a prospective pilot study.

J Am Geriatr Soc 2013 Nov;61(11):2043-4

Section of Hematology/Oncology, Department of Medicine, University of Chicago Medical Center, Chicago, Illinois; Geriatrics & Palliative Medicine, Department of Medicine, University of Chicago Medical Center, Chicago, Illinois.

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http://doi.wiley.com/10.1111/jgs.12536
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http://dx.doi.org/10.1111/jgs.12536DOI Listing
November 2013

Prognostic and predictive blood-based biomarkers in patients with advanced pancreatic cancer: results from CALGB80303 (Alliance).

Clin Cancer Res 2013 Dec 4;19(24):6957-66. Epub 2013 Oct 4.

Authors' Affiliations: Division of Medical Oncology; Alliance Statistics and Data Center, Duke University Medical Center; Durham, North Carolina; Section of Hematology/Oncology, University of Chicago Cancer Research Center; Chicago, Illinois; Department of Surgery, Brigham and Women's Hospital & Harvard Medical School; Boston, Massachusetts; Department of Internal Medicine, Ohio State University; Columbus, Ohio; and Division of Medical Oncology, University of California, San Francisco, California.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-13-0926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219241PMC
December 2013

Variability of tumor area measurements for response assessment in malignant pleural mesothelioma.

Med Phys 2013 Aug;40(8):081916

Department of Radiology, The University of Chicago, 5841 South Maryland Avenue, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1118/1.4810940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739828PMC
August 2013

MARS: a sense of perspective and an inconvenient truth.

J Thorac Oncol 2013 May;8(5):e49-50

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http://dx.doi.org/10.1097/JTO.0b013e318292c79fDOI Listing
May 2013

Quality of life after radical pleurectomy decortication for malignant pleural mesothelioma.

Ann Thorac Surg 2012 Oct 24;94(4):1086-92. Epub 2012 Aug 24.

Department of Surgery, University of Illinois, Mount Sinai Hospital, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1016/j.athoracsur.2012.05.102DOI Listing
October 2012

Personalized colon cancer care in 2010.

Semin Oncol 2011 Apr;38(2):284-308

Department of Medicine, The University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1053/j.seminoncol.2011.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065981PMC
April 2011

Computerized segmentation and measurement of malignant pleural mesothelioma.

Med Phys 2011 Jan;38(1):238-44

Department of Radiology, The University of Chicago, 5841 South Maryland Avenue, Chicago, Illinois 60637, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021556PMC
http://dx.doi.org/10.1118/1.3525836DOI Listing
January 2011

Cetuximab is associated with excessive toxicity when combined with bevacizumab Plus mFOLFOX6 in metastatic colorectal carcinoma.

Clin Colorectal Cancer 2010 Dec;9(5):290-6

New York Cancer Consortium and the University of Chicago Phase II Consortium, including Weill Cornell Medical College, New York, NY, USA.

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http://dx.doi.org/10.3816/CCC.2010.n.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623373PMC
December 2010

Quantitative measurement of lung reexpansion in malignant pleural mesothelioma patients undergoing pleurectomy/decortication.

Acad Radiol 2011 Mar 10;18(3):294-8. Epub 2010 Dec 10.

Department of Radiology, The University of Chicago, 5841 S. Maryland Ave., Chicago, IL 60637, USA.

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http://dx.doi.org/10.1016/j.acra.2010.10.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075578PMC
March 2011

A multicenter, phase II study of bortezomib (PS-341) in patients with unresectable or metastatic gastric and gastroesophageal junction adenocarcinoma.

Invest New Drugs 2011 Dec 25;29(6):1475-81. Epub 2010 Jun 25.

Gastrointestinal Oncology Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

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http://link.springer.com/10.1007/s10637-010-9474-7
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http://dx.doi.org/10.1007/s10637-010-9474-7DOI Listing
December 2011

The epothilone B analogue ixabepilone in patients with advanced hepatobiliary cancers: a trial of the University of Chicago Phase II Consortium.

Invest New Drugs 2010 Dec 11;28(6):854-8. Epub 2009 Aug 11.

Feinberg School of Medicine, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, 676 North St. Clair Street, suite 850, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1007/s10637-009-9297-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635688PMC
December 2010

Protein kinase C beta in malignant pleural mesothelioma.

Anticancer Drugs 2008 Oct;19(9):841-8

Section of Hematology/Oncology, Department of Medicine, University of Chicago Pritzker School of Medicine, Chicago, Illinois 60637-1470, USA.

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http://dx.doi.org/10.1097/CAD.0b013e32830ce506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605682PMC
October 2008

Current state and future directions of pleural mesothelioma imaging.

Lung Cancer 2008 Mar 3;59(3):411-20. Epub 2007 Dec 3.

Department of Radiology, The University of Chicago, 5841 S. Maryland Ave., MC 2026, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1016/j.lungcan.2007.09.027DOI Listing
March 2008

Preclinical studies of the proteasome inhibitor bortezomib in malignant pleural mesothelioma.

Cancer Chemother Pharmacol 2008 Apr 24;61(4):549-58. Epub 2007 May 24.

The Thoracic Surgery Oncology Laboratory and the Division of Thoracic Surgery, Brigham and Women's Hospital, Harvard Medical School, 75 Francis St., Boston, MA, 02115, USA.

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http://dx.doi.org/10.1007/s00280-007-0500-1DOI Listing
April 2008