Hedwig E Deubzer

Hedwig E Deubzer

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Hedwig E Deubzer

Hedwig E Deubzer

Publications by authors named "Hedwig E Deubzer"

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36Publications

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Transmission of chromosomally integrated human herpes virus-6A via haploidentical stem cell transplantation poses a risk for virus reactivation and associated complications.

Bone Marrow Transplant 2019 Apr 15. Epub 2019 Apr 15.

Department of Pediatric Hematology and Oncology, Charité - Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.

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http://dx.doi.org/10.1038/s41409-019-0530-4DOI Listing
April 2019

Synergistic activity of BET inhibitor MK-8628 and PLK inhibitor Volasertib in preclinical models of medulloblastoma.

Cancer Lett 2019 Mar 4;445:24-33. Epub 2019 Jan 4.

Department of Pediatric Oncology/Hematology, Charité-Universitätsmedizin Berlin, Germany; German Consortium for Translational Cancer Research (DKTK), Berlin, Germany; Berlin Institute of Health (BIH), Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2018.12.012DOI Listing
March 2019

Reactivating TP53 signaling by the novel MDM2 inhibitor DS-3032b as a therapeutic option for high-risk neuroblastoma.

Oncotarget 2018 Jan 18;9(2):2304-2319. Epub 2017 Dec 18.

Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Pediatric Hematology/Oncology/Stem Cell Transplantation, Berlin, Germany.

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http://dx.doi.org/10.18632/oncotarget.23409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788641PMC
January 2018

Using droplet digital PCR to analyze and copy number in plasma from patients with neuroblastoma.

Oncotarget 2017 Oct 7;8(49):85234-85251. Epub 2017 Jul 7.

Department of Pediatric Hematology, Oncology and Stem Cell Transplantation, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.18632/oncotarget.19076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689606PMC
October 2017

Neuroblastoma cells depend on HDAC11 for mitotic cell cycle progression and survival.

Cell Death Dis 2017 03 2;8(3):e2635. Epub 2017 Mar 2.

Department of Pediatric Hematology, Oncology and SCT, Charité-Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, Berlin 13353, Germany.

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http://dx.doi.org/10.1038/cddis.2017.49DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386552PMC
March 2017

Minichromosome Maintenance Complex Is a Critical Node in the miR-183 Signaling Network of MYCN-Amplified Neuroblastoma Cells.

J Proteome Res 2016 07 9;15(7):2178-86. Epub 2016 Jun 9.

Department of Pediatric Hematology/Oncology/Stem Cell Transplantation Charité - Universitätsmedizin Berlin , Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany.

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http://dx.doi.org/10.1021/acs.jproteome.6b00134DOI Listing
July 2016

GRHL1 acts as tumor suppressor in neuroblastoma and is negatively regulated by MYCN and HDAC3.

Cancer Res 2014 May 13;74(9):2604-16. Epub 2014 Jan 13.

Authors' Affiliations: Clinical Cooperation Unit Pediatric Oncology; Departments of Biostatistics and Tumor Genetics; Clinical Cooperation Unit Neuropathology; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ); Departments of Neuropathology and Pediatric Hematology and Oncology, University of Heidelberg, Heidelberg; Transcriptome Analysis Laboratory, University of Goettingen, Goettingen; St. Lukas Klinik Solingen, Solingen; Department of Pediatric Hematology and Oncology; and Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-1904DOI Listing
May 2014

HDAC11 is a novel drug target in carcinomas.

Int J Cancer 2013 May 25;132(9):2200-8. Epub 2012 Oct 25.

Clinical Cooperation Unit Pediatric Oncology (G340), German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.27876DOI Listing
May 2013

Nestin expression identifies ependymoma patients with poor outcome.

Brain Pathol 2012 Nov 30;22(6):848-60. Epub 2012 May 30.

Clinical Cooperation Unit Pediatric Oncology, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1111/j.1750-3639.2012.00600.xDOI Listing
November 2012

Parvovirus H1 selectively induces cytotoxic effects on human neuroblastoma cells.

Int J Cancer 2010 Sep;127(5):1230-9

Program Infection and Cancer, Department F010 and INSERM U701, German Cancer Research Center, Im Neuenheimer Feld 242, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.25168DOI Listing
September 2010

Enhancement of radiation response in osteosarcoma and rhabdomyosarcoma cell lines by histone deacetylase inhibition.

Int J Radiat Oncol Biol Phys 2010 Sep 18;78(1):237-45. Epub 2010 Jun 18.

Department of Pediatric Oncology, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.ijrobp.2010.03.010DOI Listing
September 2010

HDAC5 and HDAC9 in medulloblastoma: novel markers for risk stratification and role in tumor cell growth.

Clin Cancer Res 2010 Jun 22;16(12):3240-52. Epub 2010 Apr 22.

Clinical Cooperation Unit Pediatric Oncology, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-10-0395DOI Listing
June 2010

Targeting of HDAC8 and investigational inhibitors in neuroblastoma.

Expert Opin Investig Drugs 2009 Nov;18(11):1605-17

German Cancer Research Center, CCU Pediatric Oncology, INF 280, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1517/14728220903241658DOI Listing
November 2009

HDAC family: What are the cancer relevant targets?

Cancer Lett 2009 May 27;277(1):8-21. Epub 2008 Sep 27.

CCU Pediatric Oncology (G340), German Cancer Research Center, Im Neuenheimer Feld 280, Heidelberg, Germany.

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http://www.ibrarian.net/navon/paper/HDAC_family__What_are_th
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http://dx.doi.org/10.1016/j.canlet.2008.08.016DOI Listing
May 2009

Stepwise accumulation of distinct genomic aberrations in a patient with progressively metastasizing ependymoma.

Genes Chromosomes Cancer 2009 Mar;48(3):229-38

Clinical Cooperation Unit Pediatric Oncology (G340), German Cancer Research Center, Heidelberg, Germany.

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http://doi.wiley.com/10.1002/gcc.20635
Publisher Site
http://dx.doi.org/10.1002/gcc.20635DOI Listing
March 2009

Transcription factor AP2alpha (TFAP2a) regulates differentiation and proliferation of neuroblastoma cells.

Cancer Lett 2008 Nov 11;271(1):56-63. Epub 2008 Jul 11.

Department of Pediatric Oncology and Hematology, University Children's Hospital Essen, Essen, Germany.

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http://dx.doi.org/10.1016/j.canlet.2008.05.039DOI Listing
November 2008

Identification of novel small-molecule histone deacetylase inhibitors by medium-throughput screening using a fluorigenic assay.

Biochem J 2008 Jul;413(1):143-50

Department of Molecular Genetics and Preparative Molecular Biology, Institute for Microbiology and Genetics, Grisebachstrasse 8, 37077 Göttingen, Germany.

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http://dx.doi.org/10.1042/BJ20080536DOI Listing
July 2008

Histone deacetylase inhibitor Helminthosporium carbonum (HC)-toxin suppresses the malignant phenotype of neuroblastoma cells.

Int J Cancer 2008 Apr;122(8):1891-900

Clinical Cooperation Unit Pediatric Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.23295DOI Listing
April 2008

Colostrum obtained from women vaccinated with pneumococcal vaccine during pregnancy inhibits epithelial adhesion of Streptococcus pneumoniae.

J Infect Dis 2004 Nov 7;190(10):1758-61. Epub 2004 Oct 7.

Imperial College, Faculty of Medicine, Department of Immunology, Chelsea and Westminster Hospital, London, United Kingdom.

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http://dx.doi.org/10.1086/424597DOI Listing
November 2004

Serotype-specific pneumococcal antibodies in breast milk of Gambian women immunized with a pneumococcal polysaccharide vaccine during pregnancy.

Pediatr Infect Dis J 2004 Nov;23(11):1023-9

Imperial College, School of Science, Technology and Medicine, Department of Immunology, Chelsea and Westminster Hospital, London, United Kingdom.

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http://dx.doi.org/10.1097/01.inf.0000143651.54880.09DOI Listing
November 2004