Hediye Erdjument-Bromage

Hediye Erdjument-Bromage

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Hediye Erdjument-Bromage

Publications by authors named "Hediye Erdjument-Bromage"

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Quantitative Comparison of Proteomes Using SILAC.

Curr Protoc Protein Sci 2019 02 20;95(1):e74. Epub 2018 Sep 20.

Kimmel Center for Biology and Medicine at the Skirball Institute and Department of Cell Biology, New York University School of Medicine, New York, New York.

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http://dx.doi.org/10.1002/cpps.74DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342620PMC
February 2019

Sample Preparation for Relative Quantitation of Proteins Using Tandem Mass Tags (TMT) and Mass Spectrometry (MS).

Methods Mol Biol 2018 ;1741:135-149

Department of Cell Biology, Kimmel Center for Biology and Medicine at the Skirball Institute, New York University School of Medicine, New York, NY 10016, USA.

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http://dx.doi.org/10.1007/978-1-4939-7659-1_11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472261PMC
December 2018

The Ubiquitination of PINK1 Is Restricted to Its Mature 52-kDa Form.

Cell Rep 2017 07;20(1):30-39

Departments of Pathology and Cell Biology, Columbia University, New York, NY 10032, USA; Department of Neurology, Columbia University, New York, NY 10032, USA; Center for Motor Neuron Biology and Diseases, Columbia University, New York, NY 10032, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.06.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745057PMC
July 2017

N-Terminal Amino Acid Sequence Determination of Proteins by N-Terminal Dimethyl Labeling: Pitfalls and Advantages When Compared with Edman Degradation Sequence Analysis.

J Biomol Tech 2016 07 7;27(2):61-74. Epub 2016 Mar 7.

1 Microchemistry and Proteomics Core Laboratory, 2 Structural Biology and 3 Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.

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http://dx.doi.org/10.7171/jbt.16-2702-002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802820PMC
July 2016

Affinity purification probes of potential use to investigate the endogenous Hsp70 interactome in cancer.

ACS Chem Biol 2014 Aug 17;9(8):1698-705. Epub 2014 Jun 17.

Program in Molecular Pharmacology and Chemistry and Department of Medicine and §Program in Molecular Biology, Proteomics Core, Memorial Sloan-Kettering Cancer Center , New York, New York 10021, United States.

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http://dx.doi.org/10.1021/cb500256uDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134716PMC
August 2014

The histone variant MacroH2A1 regulates target gene expression in part by recruiting the transcriptional coregulator PELP1.

Mol Cell Biol 2014 Jul 21;34(13):2437-49. Epub 2014 Apr 21.

Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, USA Graduate Field of Biochemistry, Molecular and Cell Biology, Cornell University, Ithaca, New York, USA Laboratory of Signaling and Gene Regulation, Cecil H. and Ida Green Center for Reproductive Biology Sciences, and Division of Basic Research, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, Texas, USA

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http://mcb.asm.org/content/34/13/2437.full.pdf
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http://mcb.asm.org/content/early/2014/04/16/MCB.01315-13.ful
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http://dx.doi.org/10.1128/MCB.01315-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054320PMC
July 2014

Aminopeptidase activities as prospective urinary biomarkers for bladder cancer.

Proteomics Clin Appl 2014 Jun 31;8(5-6):317-26. Epub 2014 Mar 31.

Protein Center, Memorial Sloan-Kettering Cancer Center, New York, NY, USA; Department of Surgery, Urology Service, Memorial Sloan-Kettering Cancer Center, New York, NY, USA; Department of Urology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1002/prca.201300118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059539PMC
June 2014

The novel ubiquitin ligase complex, SCF(Fbxw4), interacts with the COP9 signalosome in an F-box dependent manner, is mutated, lost and under-expressed in human cancers.

PLoS One 2013 2;8(5):e63610. Epub 2013 May 2.

Cancer Biology and Genetics Section, Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0063610PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642104PMC
December 2013

PRMT4 blocks myeloid differentiation by assembling a methyl-RUNX1-dependent repressor complex.

Cell Rep 2013 Dec 12;5(6):1625-38. Epub 2013 Dec 12.

Molecular Pharmacology and Chemistry Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA; Gerstner Sloan-Kettering Graduate School of Biomedical Sciences, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA; Department of Biochemistry and Molecular Biology, Sylvester Comprehensive Cancer Center, University of Miami, Miller School of Medicine, Miami, FL 33136, USA; Department of Medicine, Sylvester Comprehensive Cancer Center, University of Miami, Miller School of Medicine, Miami, FL 33136, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2013.11.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073674PMC
December 2013

High-level expression of a full-length Eph receptor.

Protein Expr Purif 2013 Nov 10;92(1):112-8. Epub 2013 Sep 10.

Joint Biotechnology Lab, University of Turku, BioCity 6A, 20520 Turku, Finland.

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http://dx.doi.org/10.1016/j.pep.2013.08.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919533PMC
November 2013

Proteasome-mediated processing of Def1, a critical step in the cellular response to transcription stress.

Cell 2013 Aug;154(5):983-995

Mechanisms of Transcription Laboratory, Clare Hall Laboratories, Cancer Research UK London Research Institute, South Mimms EN6 3LD, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2013.07.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778974PMC
August 2013

USP49 deubiquitinates histone H2B and regulates cotranscriptional pre-mRNA splicing.

Genes Dev 2013 Jul 3;27(14):1581-95. Epub 2013 Jul 3.

Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA.

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http://dx.doi.org/10.1101/gad.211037.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731547PMC
July 2013

Monoubiquitination of filamin B regulates vascular endothelial growth factor-mediated trafficking of histone deacetylase 7.

Mol Cell Biol 2013 Apr 11;33(8):1546-60. Epub 2013 Feb 11.

Department of Biochemistry, School of Medicine, Case Western Reserve University, and Comprehensive Cancer Center of Case Western Reserve University, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1128/MCB.01146-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624255PMC
April 2013

The overlapping host responses to bacterial cyclic dinucleotides.

Microbes Infect 2012 Feb 10;14(2):188-97. Epub 2011 Sep 10.

Department of Microbiology & Immunology, Columbia University, New York, NY 10032, USA.

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http://dx.doi.org/10.1016/j.micinf.2011.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518029PMC
February 2012

Ubiquitination, localization, and stability of an anti-apoptotic BCL2-like protein, BCL2L10/BCLb, are regulated by Ubiquilin1.

Proc Natl Acad Sci U S A 2012 Jan 10;109(3):E119-26. Epub 2012 Jan 10.

Cancer Biology and Genetics Section, Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1073/pnas.1119167109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271887PMC
January 2012

Superoxide dismutase 1 (SOD1) is a target for a small molecule identified in a screen for inhibitors of the growth of lung adenocarcinoma cell lines.

Proc Natl Acad Sci U S A 2011 Sep 19;108(39):16375-80. Epub 2011 Sep 19.

High Throughput Screening Core Facility, and Organic Synthesis Core Facility, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA. or

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http://dx.doi.org/10.1073/pnas.1113554108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182729PMC
September 2011

Composition of yeast snRNPs and snoRNPs in the absence of trimethylguanosine caps reveals nuclear cap binding protein as a gained U1 component implicated in the cold-sensitivity of tgs1Δ cells.

Nucleic Acids Res 2011 Aug 10;39(15):6715-28. Epub 2011 May 10.

Department of Microbiology and Immunology, Weill Cornell Medical College, New York, NY 10065, USA.

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http://dx.doi.org/10.1093/nar/gkr279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159458PMC
August 2011

Bromodomain protein 7 interacts with PRMT5 and PRC2, and is involved in transcriptional repression of their target genes.

Nucleic Acids Res 2011 Jul 29;39(13):5424-38. Epub 2011 Mar 29.

Department of Molecular and Cellular Biochemistry, College of Medicine, The Ohio State University, Columbus, Ohio, OH 43210, USA.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gkr170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141267PMC
July 2011

Architecture of the Mediator head module.

Nature 2011 Jul 3;475(7355):240-3. Epub 2011 Jul 3.

Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, 635 Barnhill Drive, Indianapolis, Indiana 46202, USA.

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http://dx.doi.org/10.1038/nature10162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109712PMC
July 2011

Fas-associated death domain (FADD) and the E3 ubiquitin-protein ligase TRIM21 interact to negatively regulate virus-induced interferon production.

J Biol Chem 2011 Feb 23;286(8):6521-31. Epub 2010 Dec 23.

Cancer Research Laboratory and Department of Molecular and Cellular Biology, University of California, Berkeley, California 94720, USA.

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http://dx.doi.org/10.1074/jbc.M110.172288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057824PMC
February 2011

SETDB1 is involved in postembryonic DNA methylation and gene silencing in Drosophila.

PLoS One 2010 May 17;5(5):e10581. Epub 2010 May 17.

Department of Biochemistry, University of California Riverside, Riverside, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0010581PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871795PMC
May 2010

Processing of autophagic protein LC3 by the 20S proteasome.

Autophagy 2010 Jan 14;6(1):126-37. Epub 2010 Jan 14.

Cell Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.4161/auto.6.1.10928DOI Listing
January 2010

Heterogeneous nuclear ribonucleoprotein L Is a subunit of human KMT3a/Set2 complex required for H3 Lys-36 trimethylation activity in vivo.

J Biol Chem 2009 Jun 30;284(23):15701-7. Epub 2009 Mar 30.

State Key Laboratory of Plant Physiology and Biochemistry, College of Biological Sciences, China Agricultural University, Beijing 100094, China.

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http://dx.doi.org/10.1074/jbc.M808431200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708867PMC
June 2009

MTERF2 is a nucleoid component in mammalian mitochondria.

Biochim Biophys Acta 2009 May 3;1787(5):296-302. Epub 2009 Feb 3.

Division of Metabolic Diseases, Karolinska Institutet, SE-141 86 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.bbabio.2009.01.018DOI Listing
May 2009

Phagocytosis in macrophages lacking Cbl reveals an unsuspected role for Fc gamma receptor signaling and actin assembly in target binding.

J Immunol 2009 May;182(9):5654-62

Department of Pharmacology, Columbia University College of Physicians & Surgeons, New York, NY 10032, USA.

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http://dx.doi.org/10.4049/jimmunol.0803942DOI Listing
May 2009

Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB.

Nat Cell Biol 2009 Apr 8;11(4):420-32. Epub 2009 Mar 8.

Department of Pathology, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.

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http://dx.doi.org/10.1038/ncb1849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830812PMC
April 2009

The H3K4 demethylase lid associates with and inhibits histone deacetylase Rpd3.

Mol Cell Biol 2009 Mar 29;29(6):1401-10. Epub 2008 Dec 29.

Department of Biochemistry and Biophysics, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7295.

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http://mcb.asm.org/content/early/2008/12/29/MCB.01643-08.ful
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http://mcb.asm.org/cgi/doi/10.1128/MCB.01643-08
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http://dx.doi.org/10.1128/MCB.01643-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2648242PMC
March 2009

JAMP optimizes ERAD to protect cells from unfolded proteins.

Mol Biol Cell 2008 Nov 10;19(11):5019-28. Epub 2008 Sep 10.

Signal Transduction Program, Burnham Institute for Medical Research, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1091/mbc.e08-08-0839DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575167PMC
November 2008

PRDM16 controls a brown fat/skeletal muscle switch.

Nature 2008 Aug;454(7207):961-7

Dana-Farber Cancer Institute and the Department of Cell Biology, Harvard Medical School, 1 Jimmy Fund Way, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/nature07182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583329PMC
August 2008

Role of integrins in the assembly and function of hensin in intercalated cells.

J Am Soc Nephrol 2008 Jun 12;19(6):1079-91. Epub 2008 Mar 12.

Pediatric Nephrology, University of Rochester Medical Center, 601 Elmwood Avenue, Box 777, Rochester, NY 14642, USA.

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http://www.jasn.org/lookup/doi/10.1681/ASN.2007070737
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http://dx.doi.org/10.1681/ASN.2007070737DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396932PMC
June 2008

The HSA domain binds nuclear actin-related proteins to regulate chromatin-remodeling ATPases.

Nat Struct Mol Biol 2008 May 13;15(5):469-76. Epub 2008 Apr 13.

Howard Hughes Medical Institute, Department of Oncological Sciences, Huntsman Cancer Institute, 2000 Circle of Hope, University of Utah, Salt Lake City, Utah 84112, USA.

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http://dx.doi.org/10.1038/nsmb.1403DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810487PMC
May 2008

Reversal of RNA polymerase II ubiquitylation by the ubiquitin protease Ubp3.

Mol Cell 2008 May;30(4):498-506

Cancer Research UK London Research Institute, Clare Hall Laboratories, Blanche Lane, South Mimms, Herts EN6 3LD, UK.

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http://dx.doi.org/10.1016/j.molcel.2008.04.018DOI Listing
May 2008

Role of hPHF1 in H3K27 methylation and Hox gene silencing.

Mol Cell Biol 2008 Mar 17;28(5):1862-72. Epub 2007 Dec 17.

Department of Biochemistry and Biophysics, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7295, USA.

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http://dx.doi.org/10.1128/MCB.01589-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2258785PMC
March 2008

SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation.

Nature 2007 Nov;450(7168):440-4

Howard Hughes Medical Institute, Division of Nucleic Acids Enzymology, Department of Biochemistry, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Jersey 08854, USA.

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http://dx.doi.org/10.1038/nature06268DOI Listing
November 2007

Myoferlin regulates vascular endothelial growth factor receptor-2 stability and function.

J Biol Chem 2007 Oct 16;282(42):30745-53. Epub 2007 Aug 16.

Department of Pharmacology and Vascular Biology & Transplantation Program, Boyer Center for Molecular Medicine, Yale University School of Medicine, New Haven, Connecticut 06536, USA.

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http://dx.doi.org/10.1074/jbc.M704798200DOI Listing
October 2007

Regulation of cell cycle progression and gene expression by H2A deubiquitination.

Nature 2007 Oct 3;449(7165):1068-72. Epub 2007 Oct 3.

Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Kaul Human Genetics Building 402A, 720 South 20th Street, Birmingham, Alabama 35294, USA.

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http://dx.doi.org/10.1038/nature06256DOI Listing
October 2007

DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA.

Nature 2007 Aug;448(7154):714-7

Department of Genetics and Development, College of Physicians and Surgeons of Columbia University, New York, New York 10032, USA.

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http://dx.doi.org/10.1038/nature05987DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650820PMC
August 2007

A histone H2A deubiquitinase complex coordinating histone acetylation and H1 dissociation in transcriptional regulation.

Mol Cell 2007 Aug;27(4):609-21

Howard Hughes Medical Institute, Department of Medicine, School of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.1016/j.molcel.2007.07.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709280PMC
August 2007

Demethylation of histone H3K36 and H3K9 by Rph1: a vestige of an H3K9 methylation system in Saccharomyces cerevisiae?

Mol Cell Biol 2007 Jun 19;27(11):3951-61. Epub 2007 Mar 19.

Department of Biochemistry and Biophysics, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7295, USA.

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http://dx.doi.org/10.1128/MCB.02180-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1900024PMC
June 2007

Genome-wide dynamics of SAPHIRE, an essential complex for gene activation and chromatin boundaries.

Mol Cell Biol 2007 Jun 19;27(11):4058-69. Epub 2007 Mar 19.

University of Utah, Huntsman Cancer Institute, 2000 Circle of Hope, Salt Lake City, UT 84112, USA.

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http://dx.doi.org/10.1128/MCB.02044-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1900013PMC
June 2007

L3MBTL1, a histone-methylation-dependent chromatin lock.

Cell 2007 Jun;129(5):915-28

Howard Hughes Medical Institute, University of Medicine and Dentistry of New Jersey, 683 Hoes Lane, Piscataway, NJ 08854, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S009286740700517
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http://dx.doi.org/10.1016/j.cell.2007.03.048DOI Listing
June 2007

The trithorax-group protein Lid is a histone H3 trimethyl-Lys4 demethylase.

Nat Struct Mol Biol 2007 Apr 11;14(4):341-3. Epub 2007 Mar 11.

Howard Hughes Medical Institute, USA.

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http://dx.doi.org/10.1038/nsmb1216DOI Listing
April 2007

Ubiquitylation of histone H2B controls RNA polymerase II transcription elongation independently of histone H3 methylation.

Genes Dev 2007 Apr 20;21(7):835-47. Epub 2007 Mar 20.

Laboratory of Chromatin Biology, The Rockefeller University, New York, New York 10021, USA.

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http://dx.doi.org/10.1101/gad.1516207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1838534PMC
April 2007

Communication between distant sites in RNA polymerase II through ubiquitylation factors and the polymerase CTD.

Cell 2007 Apr;129(1):57-68

Mechanisms of Transcription Laboratory, Cancer Research UK London Research Institute, Clare Hall Laboratories, South Mimms, UK.

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http://dx.doi.org/10.1016/j.cell.2007.01.046DOI Listing
April 2007

Phosphorylation of thyroid hormone receptor-associated nuclear receptor corepressor holocomplex by the DNA-dependent protein kinase enhances its histone deacetylase activity.

J Biol Chem 2007 Mar 22;282(13):9312-22. Epub 2007 Jan 22.

Department of Molecular and Integrative Physiology, University of Illinois, Urbana, Illinois 61801, USA.

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http://dx.doi.org/10.1074/jbc.M609009200DOI Listing
March 2007

The retinoblastoma binding protein RBP2 is an H3K4 demethylase.

Cell 2007 Mar 22;128(5):889-900. Epub 2007 Feb 22.

Howard Hughes Medical Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1016/j.cell.2007.02.013DOI Listing
March 2007

PLU-1 is an H3K4 demethylase involved in transcriptional repression and breast cancer cell proliferation.

Mol Cell 2007 Mar 15;25(6):801-12. Epub 2007 Mar 15.

Howard Hughes Medical Institute, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7295, USA.

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http://dx.doi.org/10.1016/j.molcel.2007.03.001DOI Listing
March 2007

NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN.

Cell 2007 Jan;128(1):129-39

Cell Biology Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, Box 522, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/j.cell.2006.11.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1828909PMC
January 2007

Defects in energy homeostasis in Leigh syndrome French Canadian variant through PGC-1alpha/LRP130 complex.

Genes Dev 2006 Nov 18;20(21):2996-3009. Epub 2006 Oct 18.

Dana-Farber Cancer Institute and the Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1101/gad.1483906DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1620022PMC
November 2006

BAFF controls B cell metabolic fitness through a PKC beta- and Akt-dependent mechanism.

J Exp Med 2006 Oct 23;203(11):2551-62. Epub 2006 Oct 23.

Laboratory of Lymphocyte Signaling, The Rockefeller University, New York, NY 10021, USA.

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http://dx.doi.org/10.1084/jem.20060990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118121PMC
October 2006

Brd4 links chromatin targeting to HPV transcriptional silencing.

Genes Dev 2006 Sep 18;20(17):2383-96. Epub 2006 Aug 18.

Department of Biochemistry, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.

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http://dx.doi.org/10.1101/gad.1448206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1560413PMC
September 2006

Highly efficient selenomethionine labeling of recombinant proteins produced in mammalian cells.

Protein Sci 2006 Aug 5;15(8):2008-13. Epub 2006 Jul 5.

Department of Biochemistry, Virginia Commonwealth University, Richmond, 23298, USA.

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http://doi.wiley.com/10.1110/ps.062244206
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http://dx.doi.org/10.1110/ps.062244206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242577PMC
August 2006

The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36.

Nature 2006 Jul 28;442(7100):312-6. Epub 2006 May 28.

Howard Hughes Medical Institute, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7295, USA.

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http://dx.doi.org/10.1038/nature04853DOI Listing
July 2006

A CK2-dependent mechanism for degradation of the PML tumor suppressor.

Cell 2006 Jul;126(2):269-83

Cancer Biology and Genetics Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/j.cell.2006.05.041DOI Listing
July 2006

PU.1 and a TTTAAA element in the myeloid defensin-1 promoter create an operational TATA box that can impose cell specificity onto TFIID function.

J Immunol 2006 Jun;176(11):6906-17

Molecular Biology Program, Memorial Sloan-Kettering Cancer Center, and Weill Graduate School of Medical Sciences, Cornell University, New York, NY 10021, USA.

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http://dx.doi.org/10.4049/jimmunol.176.11.6906DOI Listing
June 2006

Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway.

Cell 2006 Jun;125(5):929-41

Cancer Biology and Genetics Program and Howard Hughes Medical Institute, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/j.cell.2006.03.045DOI Listing
June 2006

JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor.

Cell 2006 May 6;125(3):483-95. Epub 2006 Apr 6.

Howard Hughes Medical Institute, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1016/j.cell.2006.03.027DOI Listing
May 2006

Histone H3 and H4 ubiquitylation by the CUL4-DDB-ROC1 ubiquitin ligase facilitates cellular response to DNA damage.

Mol Cell 2006 May;22(3):383-94

Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Kaul Human Genetics Building Room 402A, 720 South 20th Street, 35294, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S109727650600230
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http://dx.doi.org/10.1016/j.molcel.2006.03.035DOI Listing
May 2006

The RSC chromatin remodeling complex bears an essential fungal-specific protein module with broad functional roles.

Genetics 2006 Feb 3;172(2):795-809. Epub 2005 Oct 3.

Howard Hughes Medical Institute, University of Utah School of Medicine, Salt Lake City 84112, USA.

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http://www.genetics.org/cgi/doi/10.1534/genetics.105.047589
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http://dx.doi.org/10.1534/genetics.105.047589DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1456245PMC
February 2006

Histone demethylation by a family of JmjC domain-containing proteins.

Nature 2006 Feb 18;439(7078):811-6. Epub 2005 Dec 18.

Howard Hughes Medical Institute, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7295, USA.

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http://www.nature.com/articles/nature04433
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http://dx.doi.org/10.1038/nature04433DOI Listing
February 2006

Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation.

Mol Cell 2005 Nov;20(4):601-11

Howard Hughes Medical Institute, Division of Nucleic Acids Enzymology, Department of Biochemistry, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, 683 Hoes Lane, Piscataway, New Jersey 08854, USA.

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http://dx.doi.org/10.1016/j.molcel.2005.09.025DOI Listing
November 2005

Adhesion signaling by a novel mitotic substrate of src kinases.

Oncogene 2005 Aug;24(34):5333-43

School of Medicine, University of California, San Francisco, CA 94143, USA.

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http://www.nature.com/articles/1208582
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http://dx.doi.org/10.1038/sj.onc.1208582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023961PMC
August 2005

Mycobacterium tuberculosis appears to lack alpha-ketoglutarate dehydrogenase and encodes pyruvate dehydrogenase in widely separated genes.

Mol Microbiol 2005 Aug;57(3):859-68

Department of Microbiology and Immunology, Weill Medical College of Cornell University, 1300 York Avenue, New York, NY 10021, USA.

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http://doi.wiley.com/10.1111/j.1365-2958.2005.04741.x
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August 2005

A direct interaction between the RAG2 C terminus and the core histones is required for efficient V(D)J recombination.

Immunity 2005 Aug;23(2):203-12

Immunobiology Center, Mount Sinai School of Medicine, New York, New York 10029, USA.

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http://dx.doi.org/10.1016/j.immuni.2005.07.004DOI Listing
August 2005

The human PAF complex coordinates transcription with events downstream of RNA synthesis.

Genes Dev 2005 Jul;19(14):1668-73

Howard Hughes Medical Institute, Division of Nucleic Acids Enzymology, Department of Biochemistry, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA.

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http://dx.doi.org/10.1101/gad.1292105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1176003PMC
July 2005