Hector De Leon

Hector De Leon

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Hector De Leon

Hector De Leon

Publications by authors named "Hector De Leon"

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Oxygenation strategies for encapsulated islet and beta cell transplants.

Adv Drug Deliv Rev 2019 01 8;139:139-156. Epub 2019 May 8.

University of Arizona, Department of Surgery, Institute of Cellular Transplantation, Tucson, AZ 85721, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S0169409X193005
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http://dx.doi.org/10.1016/j.addr.2019.05.002DOI Listing
January 2019

Systems Biology Research into Cardiovascular Disease: Contributions of Lipidomics-based Approaches to Biomarker Discovery.

Curr Drug Discov Technol 2015 ;12(3):129-54

Biological Systems Research, Philip Morris International R&D, Quai Jeanrenaud 5CH-2000 Neuchatel, Switzerland.

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http://dx.doi.org/10.2174/1570163812666150702123319DOI Listing
August 2016

Potential Role of Axonal Chemorepellent Slit2 in Modulating Adventitial Inflammation in a Rat Carotid Artery Balloon Injury Model.

J Cardiovasc Pharmacol 2016 05;67(5):433-41

*Cardiovascular Research Institute, Morehouse School of Medicine, Atlanta, GA; and †The Winship Cancer Institute, Emory University School of Medicine, Atlanta GA.

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http://dx.doi.org/10.1097/FJC.0000000000000369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861666PMC
May 2016

Systems toxicology-based assessment of the candidate modified risk tobacco product THS2.2 for the adhesion of monocytic cells to human coronary arterial endothelial cells.

Toxicology 2016 Jan 2;339:73-86. Epub 2015 Dec 2.

Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000 Neuchâtel, Switzerland.

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http://dx.doi.org/10.1016/j.tox.2015.11.007DOI Listing
January 2016

Aerosol from a candidate modified risk tobacco product has reduced effects on chemotaxis and transendothelial migration compared to combustion of conventional cigarettes.

Food Chem Toxicol 2015 Dec 1;86:81-7. Epub 2015 Oct 1.

Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000 Neuchâtel, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.fct.2015.09.016DOI Listing
December 2015

Systems Biology Reveals Cigarette Smoke-Induced Concentration-Dependent Direct and Indirect Mechanisms That Promote Monocyte-Endothelial Cell Adhesion.

Toxicol Sci 2015 Oct 2;147(2):370-85. Epub 2015 Jul 2.

Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000 Neuchâtel, Switzerland.

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http://dx.doi.org/10.1093/toxsci/kfv137DOI Listing
October 2015

A prototypic modified risk tobacco product exhibits reduced effects on chemotaxis and transendothelial migration of monocytes compared with a reference cigarette.

Food Chem Toxicol 2015 Jun 31;80:277-286. Epub 2015 Mar 31.

Philip Morris Products S.A., Philip Morris International R&D, Quai Jeanrenaud 5, 2000 Neuchâtel, Switzerland.

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http://dx.doi.org/10.1016/j.fct.2015.03.026DOI Listing
June 2015

Construction of biological networks from unstructured information based on a semi-automated curation workflow.

Database (Oxford) 2015 Jun 17;2015:bav057. Epub 2015 Jun 17.

Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000 Neuchâtel, Switzerland and.

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http://dx.doi.org/10.1093/database/bav057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630939PMC
June 2015

A model-based approach to investigating the pathophysiological mechanisms of hypertension and response to antihypertensive therapies: extending the Guyton model.

Am J Physiol Regul Integr Comp Physiol 2014 May 5;306(9):R647-62. Epub 2014 Feb 5.

Department of Modeling and Simulation, Primary Care Franchise, Novartis Pharmaceuticals Corporation, East Hanover, New Jersey;

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http://dx.doi.org/10.1152/ajpregu.00039.2013DOI Listing
May 2014

Laparoscopic vs. open total mesorectal excision for treatment of rectal cancer.

Rev Invest Clin 2008 May-Jun;60(3):205-11

Departamento de Cirugía, Servicio de Colon y Recto Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México, D.F.

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December 2008

[Mortality-associated factors in major surgery: retrospective analysis in a referral center].

Rev Invest Clin 2006 Jan-Feb;58(1):9-14

Departamento de Cirugía, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, DF México.

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August 2006

Neuronal chemorepellent Slit2 inhibits vascular smooth muscle cell migration by suppressing small GTPase Rac1 activation.

Circ Res 2006 Mar 26;98(4):480-9. Epub 2006 Jan 26.

Cardiovascular Research Institute, Morehouse School of Medicine, Atlanta, GA, USA.

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http://dx.doi.org/10.1161/01.RES.0000205764.85931.4bDOI Listing
March 2006

Rad GTPase attenuates vascular lesion formation by inhibition of vascular smooth muscle cell migration.

Circulation 2005 Mar 14;111(8):1071-7. Epub 2005 Feb 14.

Cardiovascular Research Institute, Morehouse School of Medicine, Atlanta, Ga 30310, USA.

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http://dx.doi.org/10.1161/01.CIR.0000156439.55349.ADDOI Listing
March 2005

Endovascular irradiation impairs vascular functional responses in noninjured pig coronary arteries.

Cardiovasc Radiat Med 2002 Jul-Dec;3(3-4):152-62

American Cardiovascular Research Institute, 3155 Northwoods Place, Norcross, GA 30071, USA.

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http://dx.doi.org/10.1016/s1522-1865(03)00096-9DOI Listing
December 2003

Mortality rates of interventional and surgical procedures performed in domestic juvenile farm pigs and Yucatan mini-pigs.

Contemp Top Lab Anim Sci 2003 May;42(3):29-33

American Cardiovascular Research Institute, Norcross, Georgia 30071, USA.

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May 2003

Vasomotor function of pig coronary arteries after chronic coronary occlusion.

J Cardiovasc Pharmacol 2003 Apr;41(4):600-8

The American Cardiovascular Research Institute, Norcross, Georgia 30071, USA.

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http://dx.doi.org/10.1097/00005344-200304000-00013DOI Listing
April 2003