Heather S Duffy

Heather S Duffy

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Heather S Duffy

Heather S Duffy

Publications by authors named "Heather S Duffy"

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Role of connexins and pannexins in cardiovascular physiology.

Cell Mol Life Sci 2015 Aug 20;72(15):2779-92. Epub 2015 Jun 20.

Department of Pathology and Immunology, University of Geneva, Rue Michel-Servet 1, 1211, Geneva 4, Switzerland.

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http://link.springer.com/content/pdf/10.1007/s00018-015-1959
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http://link.springer.com/10.1007/s00018-015-1959-2
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http://dx.doi.org/10.1007/s00018-015-1959-2DOI Listing
August 2015

Mitochondria oxidative stress, connexin43 remodeling, and sudden arrhythmic death.

Circ Arrhythm Electrophysiol 2013 Jun 4;6(3):623-31. Epub 2013 Apr 4.

Section of Cardiology and Center for Cardiovascular Research, University of Illinois at Chicago, IL, USA.

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http://dx.doi.org/10.1161/CIRCEP.112.976787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716298PMC
June 2013

Cardiomyocyte ATP release through pannexin 1 aids in early fibroblast activation.

Am J Physiol Heart Circ Physiol 2012 Nov 14;303(10):H1208-18. Epub 2012 Sep 14.

Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1152/ajpheart.00251.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517637PMC
November 2012

Omega 3 fatty acid inhibition of inflammatory cytokine-mediated Connexin43 regulation in the heart.

Front Physiol 2012 12;3:272. Epub 2012 Jul 12.

Beth Israel Deaconess Medical Center, Harvard Medical School Boston, MA, USA.

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http://dx.doi.org/10.3389/fphys.2012.00272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429046PMC
October 2012

The molecular mechanisms of gap junction remodeling.

Authors:
Heather S Duffy

Heart Rhythm 2012 Aug 28;9(8):1331-4. Epub 2011 Nov 28.

Harvard Medical School, Boston, Massachusetts 02115, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S15475271110144
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http://dx.doi.org/10.1016/j.hrthm.2011.11.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378775PMC
August 2012

Endothelial cells require related transcription enhancer factor-1 for cell-cell connections through the induction of gap junction proteins.

Arterioscler Thromb Vasc Biol 2012 Aug 31;32(8):1951-9. Epub 2012 May 31.

Institute of Molecular Medicine, Peking University, Beijing, China.

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http://dx.doi.org/10.1161/ATVBAHA.112.250159DOI Listing
August 2012

Myofibroblasts cause heterogeneous Cx43 reduction and are unlikely to be coupled to myocytes in the healing canine infarct.

Am J Physiol Heart Circ Physiol 2012 Feb 18;302(3):H790-800. Epub 2011 Nov 18.

Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1152/ajpheart.00498.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353799PMC
February 2012

Inhibition of c-Src tyrosine kinase prevents angiotensin II-mediated connexin-43 remodeling and sudden cardiac death.

J Am Coll Cardiol 2011 Nov;58(22):2332-9

Section of Cardiology and Center for Cardiovascular Research, University of Illinois at Chicago, 840 S.Wood Street, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1016/j.jacc.2011.07.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226807PMC
November 2011

Pannexin channels are not gap junction hemichannels.

Channels (Austin) 2011 May-Jun;5(3):193-7. Epub 2011 May 1.

National Center for Microscopy and Imaging Research, University of California, San Diego, La Jolla, CA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704572PMC
http://dx.doi.org/10.4161/chan.5.3.15765DOI Listing
October 2011

Fibroblasts and myofibroblasts: what are we talking about?

J Cardiovasc Pharmacol 2011 Apr;57(4):376-9

Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1097/FJC.0b013e3182116e39DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077448PMC
April 2011

Fibroblasts, myofibroblasts, and fibrosis: fact, fiction, and the future.

Authors:
Heather S Duffy

J Cardiovasc Pharmacol 2011 Apr;57(4):373-5

Beth Israel Deaconess Medical Center, Harvard Medical School, Center for Life Sciences 913, 3 Blackfan Circle, Boston, MA 02115, USA.

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http://dx.doi.org/10.1097/FJC.0b013e3182155a38DOI Listing
April 2011

TVP1022 protects neonatal rat ventricular myocytes against doxorubicin-induced functional derangements.

J Pharmacol Exp Ther 2010 Feb 13;332(2):413-20. Epub 2009 Nov 13.

Department of Physiology, Ruth and Bruce Rappaport Faculty of Medicine, Haifa 31096, Israel.

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http://dx.doi.org/10.1124/jpet.109.161158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202463PMC
February 2010

Structural and molecular mechanisms of gap junction remodeling in epicardial border zone myocytes following myocardial infarction.

Circ Res 2009 May 2;104(9):1103-12. Epub 2009 Apr 2.

Department of Cardiology, Center for Life Sciences 9-913, Beth Israel Deaconess Medical Center, 3 Blackfan Circle, Boston, MA 02115, USA.

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http://dx.doi.org/10.1161/CIRCRESAHA.108.190454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892879PMC
May 2009

Cardiac connections--the antiarrhythmic solution?

Authors:
Heather S Duffy

N Engl J Med 2008 Mar;358(13):1397-8

Department of Pharmacology, College of Physicians and Surgeons, Columbia University, New York, USA.

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http://dx.doi.org/10.1056/NEJMcibr0708922DOI Listing
March 2008

Drug development for treatment of cardiac arrhythmias: targeting the gap junctions.

Am J Physiol Heart Circ Physiol 2008 Jan 21;294(1):H16-8. Epub 2007 Sep 21.

College of Physicians & Surgeons of Columbia University, 630 W. 168th Street, New York, NY 10032, USA.

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http://dx.doi.org/10.1152/ajpheart.01031.2007DOI Listing
January 2008

Is there a role for remodeled connexins in AF? No simple answers.

J Mol Cell Cardiol 2008 Jan 4;44(1):4-13. Epub 2007 Sep 4.

Columbia University, New York, New York 10032, USA.

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http://dx.doi.org/10.1016/j.yjmcc.2007.08.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2243184PMC
January 2008

Early electrical remodeling in rabbit pulmonary vein results from trafficking of intracellular SK2 channels to membrane sites.

Cardiovasc Res 2007 Sep 10;75(4):758-69. Epub 2007 May 10.

Center for Molecular Therapeutics, Department of Pharmacology, College of Physicians and Surgeons of Columbia University, New York, New York 10032, USA.

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http://dx.doi.org/10.1016/j.cardiores.2007.05.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2034441PMC
September 2007

Gap junctional complexes: from partners to functions.

Prog Biophys Mol Biol 2007 May-Jun;94(1-2):29-65. Epub 2007 Mar 19.

Interactions et Communications Cellulaires, Université de Poitiers, Poitiers, France.

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http://dx.doi.org/10.1016/j.pbiomolbio.2007.03.010DOI Listing
August 2007

Cleft diving: looking in the extracellular matrix for answers to atrial arrhythmias.

Authors:
Heather S Duffy

Heart Rhythm 2007 Jul 6;4(7):950-1. Epub 2007 Apr 6.

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http://dx.doi.org/10.1016/j.hrthm.2007.03.039DOI Listing
July 2007

The gap junction protein connexin32 interacts with the Src homology 3/hook domain of discs large homolog 1.

J Biol Chem 2007 Mar 5;282(13):9789-96. Epub 2007 Feb 5.

Department of Pharmacology, Columbia University, New York, New York 10032, USA.

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http://dx.doi.org/10.1074/jbc.M605261200DOI Listing
March 2007

Heterogeneous gap junction remodeling in reentrant circuits in the epicardial border zone of the healing canine infarct.

Cardiovasc Res 2006 Nov 12;72(2):241-9. Epub 2006 Jul 12.

Department of Pharmacology, College of Physicians and Surgeons, Columbia University New York, NY 10032, USA.

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http://dx.doi.org/10.1016/j.cardiores.2006.07.005DOI Listing
November 2006

How do myocytes tell right from left?

Authors:
Heather S Duffy

Circ Res 2006 Sep;99(6):563-4

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http://dx.doi.org/10.1161/01.RES.0000243582.08718.01DOI Listing
September 2006

Cardiac connexins: genes to nexus.

Adv Cardiol 2006 ;42:1-17

Department of Neuroscience, Albert Einstein College of Medicine, Bronx, N.Y.; USA.

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http://dx.doi.org/10.1159/000092550DOI Listing
July 2006

Structural changes in the carboxyl terminus of the gap junction protein connexin43 indicates signaling between binding domains for c-Src and zonula occludens-1.

J Biol Chem 2004 Dec 18;279(52):54695-701. Epub 2004 Oct 18.

Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, Nebraska 68198, USA.

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http://dx.doi.org/10.1074/jbc.M409552200DOI Listing
December 2004

Kinetics of protein-protein interactions of connexins: use of enzyme linked sorbent assays.

Cell Commun Adhes 2003 Jul-Dec;10(4-6):207-10

Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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November 2004

Modifications in the biophysical properties of connexin43 channels by a peptide of the cytoplasmic loop region.

Circ Res 2004 Aug 29;95(4):e22-8. Epub 2004 Jul 29.

Department of Pharmacology, State University of New York Upstate Medical University, Syracuse 13210, USA.

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http://dx.doi.org/10.1161/01.RES.0000140737.62245.c5DOI Listing
August 2004

pH-dependent dimerization of the carboxyl terminal domain of Cx43.

Biophys J 2004 Jul;87(1):574-81

Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, 68198, USA.

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http://dx.doi.org/10.1529/biophysj.103.039230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1304378PMC
July 2004

Structural bases for the chemical regulation of Connexin43 channels.

Cardiovasc Res 2004 May;62(2):268-75

Department of Pharmacology, SUNY Upstate Medical University, 766 Irving Ave, Syracuse, NY 13210, USA.

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http://dx.doi.org/10.1016/j.cardiores.2003.12.030DOI Listing
May 2004

Regulation of connexin43 protein complexes by intracellular acidification.

Circ Res 2004 Feb 29;94(2):215-22. Epub 2003 Dec 29.

Department of Neuroscience, Albert Einstein College of Medicine, 1410 Pelham Pkwy S, Bronx, NY 10464, USA.

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http://dx.doi.org/10.1161/01.RES.0000113924.06926.11DOI Listing
February 2004

Formation of the gap junction nexus: binding partners for connexins.

J Physiol Paris 2002 Apr-Jun;96(3-4):243-9

Department of Neuroscience, Albert Einstein College of Medicine, 1410 Pelham Pkwy S, Bronx, NY 10461, USA.

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April 2003

pH-dependent intramolecular binding and structure involving Cx43 cytoplasmic domains.

J Biol Chem 2002 Sep 31;277(39):36706-14. Epub 2002 Jul 31.

Department of Neuroscience, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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http://dx.doi.org/10.1074/jbc.M207016200DOI Listing
September 2002