Heather M O'Hagan

Heather M O'Hagan

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Heather M O'Hagan

Heather M O'Hagan

Publications by authors named "Heather M O'Hagan"

17Publications

69Reads

1PubMed Central Citations

Inflammation-induced DNA methylation of DNA polymerase gamma alters the metabolic profile of colon tumors.

Cancer Metab 2018 10;6. Epub 2018 Jul 10.

1Medical Sciences, Indiana University School of Medicine, Bloomington, Indiana USA.

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July 2018

The Role of Inflammation and Inflammatory Mediators in the Development, Progression, Metastasis, and Chemoresistance of Epithelial Ovarian Cancer.

Cancers (Basel) 2018 Jul 30;10(8). Epub 2018 Jul 30.

Medical Sciences, Indiana University School of Medicine, Bloomington, IN 47405, USA.

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July 2018

Chronic Cigarette Smoke-Induced Epigenomic Changes Precede Sensitization of Bronchial Epithelial Cells to Single-Step Transformation by KRAS Mutations.

Cancer Cell 2017 09;32(3):360-376.e6

Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. Electronic address:

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September 2017

Mismatch Repair Proteins Initiate Epigenetic Alterations during Inflammation-Driven Tumorigenesis.

Cancer Res 2017 07 18;77(13):3467-3478. Epub 2017 May 18.

Medical Sciences, Indiana University School of Medicine, Bloomington, Indiana.

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July 2017

Mismatch repair proteins recruit DNA methyltransferase 1 to sites of oxidative DNA damage.

J Mol Cell Biol 2016 06 17;8(3):244-54. Epub 2015 Jul 17.

Medical Sciences, Indiana University School of Medicine, Bloomington, IN 47405, USA Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, IN 46202, USA

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June 2016

Chromatin modifications during repair of environmental exposure-induced DNA damage: a potential mechanism for stable epigenetic alterations.

Environ Mol Mutagen 2014 Apr 20;55(3):278-91. Epub 2013 Nov 20.

Medical Sciences, Indiana University School of Medicine, Bloomington, Indiana.

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April 2014

Increased understanding of the impact of environmental exposures on the epigenome.

Environ Mol Mutagen 2014 Apr 14;55(3):151-4. Epub 2013 Dec 14.

Medical Sciences Program, Indiana University School of Medicine, Bloomington, IN.

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April 2014

Oxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG Islands.

Cancer Cell 2011 Nov;20(5):606-19

Department of Oncology and The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.

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November 2011

Polycomb CBX7 promotes initiation of heritable repression of genes frequently silenced with cancer-specific DNA hypermethylation.

Cancer Res 2009 Aug 14;69(15):6322-30. Epub 2009 Jul 14.

The Sidney Kimmel Comprehensive Cancer Institute at Johns Hopkins, Baltimore, Maryland 21231, USA.

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August 2009

Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island.

PLoS Genet 2008 Aug 15;4(8):e1000155. Epub 2008 Aug 15.

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States of America.

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August 2008

RPA and ATR link transcriptional stress to p53.

Proc Natl Acad Sci U S A 2007 Jul 6;104(31):12778-83. Epub 2007 Jul 6.

Department of Radiation Oncology, Division of Radiation and Cancer Biology, University of Michigan Comprehensive Cancer Center, 109 Zina Pitcher Place, Ann Arbor, MI 48109-2200, USA.

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July 2007

Nuclear accumulation of p53 following inhibition of transcription is not due to diminished levels of MDM2.

Oncogene 2004 Jul;23(32):5505-12

Program in Molecular and Cellular Biology, Department of Radiation Oncology, Division of Radiation and Cancer Biology, University of Michigan Medical School, Ann Arbor, MI 48109-0936, USA.

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July 2004

Efficient NES-dependent protein nuclear export requires ongoing synthesis and export of mRNAs.

Exp Cell Res 2004 Jul;297(2):548-59

Department of Radiation Oncology, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI 48109, USA.

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July 2004

Phosphorylation and nuclear accumulation are distinct events contributing to the activation of p53.

Mutat Res 2004 Feb;546(1-2):7-15

Department of Radiation Oncology, Program in Molecular and Cellular Biology, University of Michigan Medical School, Ann Arbor, MI 48109-0936, USA.

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February 2004