Heather C Whalley

Heather C Whalley

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Heather C Whalley

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White Matter Microstructure and Its Relation to Longitudinal Measures of Depressive Symptoms in Mid- and Late Life.

Biol Psychiatry 2019 Nov 22;86(10):759-768. Epub 2019 Jun 22.

Division of Psychiatry, University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1016/j.biopsych.2019.06.011DOI Listing
November 2019

Aberrant structural covariance networks in youth at high familial risk for mood disorder.

Bipolar Disord 2019 Nov 14. Epub 2019 Nov 14.

Division of Psychiatry, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1111/bdi.12868DOI Listing
November 2019

Impact of Polygenic Risk for Schizophrenia on Cortical Structure in UK Biobank.

Biol Psychiatry 2019 Oct 22;86(7):536-544. Epub 2019 Apr 22.

Division of Psychiatry, Royal Edinburgh Hospital, Edinburgh, UK; The Patrick Wild Centre, Royal Edinburgh Hospital, Edinburgh, UK.

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http://dx.doi.org/10.1016/j.biopsych.2019.04.013DOI Listing
October 2019

The Association Between Familial Risk and Brain Abnormalities Is Disease Specific: An ENIGMA-Relatives Study of Schizophrenia and Bipolar Disorder.

Biol Psychiatry 2019 Oct 13;86(7):545-556. Epub 2019 Jun 13.

Department of Psychiatry, University Medical Center Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands; Department of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Center-Sophia Children's Hospital, Rotterdam, Netherlands.

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http://dx.doi.org/10.1016/j.biopsych.2019.03.985DOI Listing
October 2019

White matter disturbances in major depressive disorder: a coordinated analysis across 20 international cohorts in the ENIGMA MDD working group.

Mol Psychiatry 2019 Aug 30. Epub 2019 Aug 30.

Orygen, The National Centre of Excellence in Youth Mental Health, Parkville, Australia.

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http://dx.doi.org/10.1038/s41380-019-0477-2DOI Listing
August 2019

Identification of novel differentially methylated sites with potential as clinical predictors of impaired respiratory function and COPD.

EBioMedicine 2019 May 29;43:576-586. Epub 2019 Mar 29.

Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S23523964193021
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http://dx.doi.org/10.1016/j.ebiom.2019.03.072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557748PMC
May 2019

10Kin1day: A Bottom-Up Neuroimaging Initiative.

Authors:
Martijn P van den Heuvel Lianne H Scholtens Hannelore K van der Burgh Federica Agosta Clara Alloza Celso Arango Bonnie Auyeung Simon Baron-Cohen Silvia Basaia Manon J N L Benders Frauke Beyer Linda Booij Kees P J Braun Geraldo Busatto Filho Wiepke Cahn Dara M Cannon Tiffany M Chaim-Avancini Sandra S M Chan Eric Y H Chen Benedicto Crespo-Facorro Eveline A Crone Udo Dannlowski Sonja M C de Zwarte Bruno Dietsche Gary Donohoe Stefan Du Plessis Sarah Durston Covadonga M Díaz-Caneja Ana M Díaz-Zuluaga Robin Emsley Massimo Filippi Thomas Frodl Martin Gorges Beata Graff Dominik Grotegerd Dariusz Gąsecki Julie M Hall Laurena Holleran Rosemary Holt Helene J Hopman Andreas Jansen Joost Janssen Krzysztof Jodzio Lutz Jäncke Vasiliy G Kaleda Jan Kassubek Shahrzad Kharabian Masouleh Tilo Kircher Martijn G J C Koevoets Vladimir S Kostic Axel Krug Stephen M Lawrie Irina S Lebedeva Edwin H M Lee Tristram A Lett Simon J G Lewis Franziskus Liem Michael V Lombardo Carlos Lopez-Jaramillo Daniel S Margulies Sebastian Markett Paulo Marques Ignacio Martínez-Zalacaín Colm McDonald Andrew M McIntosh Genevieve McPhilemy Susanne L Meinert José M Menchón Christian Montag Pedro S Moreira Pedro Morgado David O Mothersill Susan Mérillat Hans-Peter Müller Leila Nabulsi Pablo Najt Krzysztof Narkiewicz Patrycja Naumczyk Bob Oranje Victor Ortiz-Garcia de la Foz Jiska S Peper Julian A Pineda Paul E Rasser Ronny Redlich Jonathan Repple Martin Reuter Pedro G P Rosa Amber N V Ruigrok Agnieszka Sabisz Ulrich Schall Soraya Seedat Mauricio H Serpa Stavros Skouras Carles Soriano-Mas Nuno Sousa Edyta Szurowska Alexander S Tomyshev Diana Tordesillas-Gutierrez Sofie L Valk Leonard H van den Berg Theo G M van Erp Neeltje E M van Haren Judith M C van Leeuwen Arno Villringer Christiaan H Vinkers Christian Vollmar Lea Waller Henrik Walter Heather C Whalley Marta Witkowska A Veronica Witte Marcus V Zanetti Rui Zhang Siemon C de Lange

Front Neurol 2019 9;10:425. Epub 2019 May 9.

Connectome Lab, CTG, CNCR, VU Amsterdam, Amsterdam, Netherlands.

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https://www.frontiersin.org/article/10.3389/fneur.2019.00425
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http://dx.doi.org/10.3389/fneur.2019.00425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524614PMC
May 2019

Reply to: New Meta- and Mega-analyses of Magnetic Resonance Imaging Findings in Schizophrenia: Do They Really Increase Our Knowledge About the Nature of the Disease Process?

Authors:
Theo G M van Erp Esther Walton Derrek P Hibar Lianne Schmaal Wenhao Jiang David C Glahn Godfrey D Pearlson Nailin Yao Masaki Fukunaga Ryota Hashimoto Naohiro Okada Hidenaga Yamamori Vincent P Clark Bryon A Mueller Sonja M C de Zwarte Roel A Ophoff Neeltje E M van Haren Ole A Andreassen Tiril P Gurholt Oliver Gruber Bernd Kraemer Anja Richter Vince D Calhoun Benedicto Crespo-Facorro Roberto Roiz-Santiañez Diana Tordesillas-Gutiérrez Carmel Loughland Stanley Catts Janice M Fullerton Melissa J Green Frans Henskens Assen Jablensky Bryan J Mowry Christos Pantelis Yann Quidé Ulrich Schall Rodney J Scott Murray J Cairns Marc Seal Paul A Tooney Paul E Rasser Gavin Cooper Cynthia Shannon Weickert Thomas W Weickert Elliot Hong Peter Kochunov Raquel E Gur Ruben C Gur Judith M Ford Fabio Macciardi Daniel H Mathalon Steven G Potkin Adrian Preda Fengmei Fan Stefan Ehrlich Margaret D King Lieuwe De Haan Dick J Veltman Francesca Assogna Nerisa Banaj Pietro de Rossi Mariangela Iorio Fabrizio Piras Gianfranco Spalletta Edith Pomarol-Clotet Sinead Kelly Simone Ciufolini Joaquim Radua Robin Murray Tiago Reis Marques Andrew Simmons Stefan Borgwardt Fabienne Schönborn-Harrisberger Anita Riecher-Rössler Renata Smieskova Kathryn I Alpert Alessandro Bertolino Aurora Bonvino Annabella Di Giorgio Emma Neilson Andrew R Mayer Je-Yeon Yun Dara M Cannon Irina Lebedeva Alexander S Tomyshev Tolibjohn Akhadov Vasily Kaleda Helena Fatouros-Bergman Lena Flyckt Pedro G P Rosa Mauricio H Serpa Marcus V Zanetti Cyril Hoschl Antonin Skoch Filip Spaniel David Tomecek Andrew M McIntosh Heather C Whalley Christian Knöchel Viola Oertel-Knöchel Fleur M Howells Dan J Stein Henk S Temmingh Anne Uhlmann Carlos Lopez-Jaramillo Danai Dima Joshua I Faskowitz Boris A Gutman Neda Jahanshad Paul M Thompson Jessica A Turner

Biol Psychiatry 2019 04 22;85(7):e35-e39. Epub 2018 Nov 22.

Imaging Genetics and Neuroinformatics Laboratory, Department of Psychology, Georgia State University, Atlanta, Georgia; Mind Research Network, Albuquerque, New Mexico.

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http://dx.doi.org/10.1016/j.biopsych.2018.10.003DOI Listing
April 2019

Decreased functional brain response to emotional arousal and increased psychiatric symptomology in FMR1 premutation carriers.

Psychiatry Res Neuroimaging 2019 03 29;285:9-17. Epub 2019 Jan 29.

Patrick Wild Centre, Division of Psychiatry, School of Molecular and Clinical Medicine, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh EH10 5HF, United Kingdom.

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http://dx.doi.org/10.1016/j.pscychresns.2019.01.011DOI Listing
March 2019

Predicting major mental illness: ethical and practical considerations.

BJPsych Open 2019 Mar;5(2):e30

Professor of Biological Psychiatry, Division of Psychiatry and Centre for Cognitive Ageing and Cognitive Epidemiology,University of Edinburgh,Scotland, UK.

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http://dx.doi.org/10.1192/bjo.2019.11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469234PMC
March 2019

Age-related functional brain changes in premutation carriers.

Neuroimage Clin 2018 9;17:761-767. Epub 2017 Dec 9.

Patrick Wild Centre, Division of Psychiatry, School of Molecular and Clinical Medicine, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh EH10 5HF, UK.

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http://dx.doi.org/10.1016/j.nicl.2017.12.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842728PMC
February 2019

Cognitive biases predict symptoms of depression, anxiety and wellbeing above and beyond neuroticism in adolescence.

J Affect Disord 2018 12 15;241:446-453. Epub 2018 Aug 15.

Department of Clinical Psychology, University of Edinburgh, Doorway 6 Medical Quad, Teviot Place, Edinburgh EH8 9AG, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jad.2018.08.051DOI Listing
December 2018

Cortical Brain Abnormalities in 4474 Individuals With Schizophrenia and 5098 Control Subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium.

Authors:
Theo G M van Erp Esther Walton Derrek P Hibar Lianne Schmaal Wenhao Jiang David C Glahn Godfrey D Pearlson Nailin Yao Masaki Fukunaga Ryota Hashimoto Naohiro Okada Hidenaga Yamamori Juan R Bustillo Vincent P Clark Ingrid Agartz Bryon A Mueller Wiepke Cahn Sonja M C de Zwarte Hilleke E Hulshoff Pol René S Kahn Roel A Ophoff Neeltje E M van Haren Ole A Andreassen Anders M Dale Nhat Trung Doan Tiril P Gurholt Cecilie B Hartberg Unn K Haukvik Kjetil N Jørgensen Trine V Lagerberg Ingrid Melle Lars T Westlye Oliver Gruber Bernd Kraemer Anja Richter David Zilles Vince D Calhoun Benedicto Crespo-Facorro Roberto Roiz-Santiañez Diana Tordesillas-Gutiérrez Carmel Loughland Vaughan J Carr Stanley Catts Vanessa L Cropley Janice M Fullerton Melissa J Green Frans A Henskens Assen Jablensky Rhoshel K Lenroot Bryan J Mowry Patricia T Michie Christos Pantelis Yann Quidé Ulrich Schall Rodney J Scott Murray J Cairns Marc Seal Paul A Tooney Paul E Rasser Gavin Cooper Cynthia Shannon Weickert Thomas W Weickert Derek W Morris Elliot Hong Peter Kochunov Lauren M Beard Raquel E Gur Ruben C Gur Theodore D Satterthwaite Daniel H Wolf Aysenil Belger Gregory G Brown Judith M Ford Fabio Macciardi Daniel H Mathalon Daniel S O'Leary Steven G Potkin Adrian Preda James Voyvodic Kelvin O Lim Sarah McEwen Fude Yang Yunlong Tan Shuping Tan Zhiren Wang Fengmei Fan Jingxu Chen Hong Xiang Shiyou Tang Hua Guo Ping Wan Dong Wei Henry J Bockholt Stefan Ehrlich Rick P F Wolthusen Margaret D King Jody M Shoemaker Scott R Sponheim Lieuwe De Haan Laura Koenders Marise W Machielsen Therese van Amelsvoort Dick J Veltman Francesca Assogna Nerisa Banaj Pietro de Rossi Mariangela Iorio Fabrizio Piras Gianfranco Spalletta Peter J McKenna Edith Pomarol-Clotet Raymond Salvador Aiden Corvin Gary Donohoe Sinead Kelly Christopher D Whelan Erin W Dickie David Rotenberg Aristotle N Voineskos Simone Ciufolini Joaquim Radua Paola Dazzan Robin Murray Tiago Reis Marques Andrew Simmons Stefan Borgwardt Laura Egloff Fabienne Harrisberger Anita Riecher-Rössler Renata Smieskova Kathryn I Alpert Lei Wang Erik G Jönsson Sanne Koops Iris E C Sommer Alessandro Bertolino Aurora Bonvino Annabella Di Giorgio Emma Neilson Andrew R Mayer Julia M Stephen Jun Soo Kwon Je-Yeon Yun Dara M Cannon Colm McDonald Irina Lebedeva Alexander S Tomyshev Tolibjohn Akhadov Vasily Kaleda Helena Fatouros-Bergman Lena Flyckt Geraldo F Busatto Pedro G P Rosa Mauricio H Serpa Marcus V Zanetti Cyril Hoschl Antonin Skoch Filip Spaniel David Tomecek Saskia P Hagenaars Andrew M McIntosh Heather C Whalley Stephen M Lawrie Christian Knöchel Viola Oertel-Knöchel Michael Stäblein Fleur M Howells Dan J Stein Henk S Temmingh Anne Uhlmann Carlos Lopez-Jaramillo Danai Dima Agnes McMahon Joshua I Faskowitz Boris A Gutman Neda Jahanshad Paul M Thompson Jessica A Turner

Biol Psychiatry 2018 11 14;84(9):644-654. Epub 2018 May 14.

Imaging Genetics and Neuroinformatics Lab, Georgia State University, Atlanta, Georgia; Mind Research Network, Albuquerque, New Mexico.

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http://dx.doi.org/10.1016/j.biopsych.2018.04.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177304PMC
November 2018

Epigenetic signatures of starting and stopping smoking.

EBioMedicine 2018 Nov 30;37:214-220. Epub 2018 Oct 30.

Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland, United Kingdom; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, Scotland, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2018.10.051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286188PMC
November 2018

Diffusion tensor imaging correlates of early markers of depression in youth at high-familial risk for bipolar disorder.

J Child Psychol Psychiatry 2018 08 28;59(8):917-927. Epub 2018 Feb 28.

Division of Psychiatry, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1111/jcpp.12879DOI Listing
August 2018

Investigating the relationship between DNA methylation age acceleration and risk factors for Alzheimer's disease.

Alzheimers Dement (Amst) 2018 21;10:429-437. Epub 2018 Jun 21.

Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland.

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http://dx.doi.org/10.1016/j.dadm.2018.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111045PMC
June 2018

Central and non-central networks, cognition, clinical symptoms, and polygenic risk scores in schizophrenia.

Hum Brain Mapp 2017 12 7;38(12):5919-5930. Epub 2017 Sep 7.

Division of Psychiatry, University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1002/hbm.23798DOI Listing
December 2017

Effects of environmental risks and polygenic loading for schizophrenia on cortical thickness.

Schizophr Res 2017 06 15;184:128-136. Epub 2016 Dec 15.

Division of Psychiatry, Centre for Brain Sciences, School of Clinical Sciences, University of Edinburgh, Royal Edinburgh Hospital, Morningside Park, Edinburgh, UK; Royal Edinburgh Hospital, Morningside Park, Edinburgh, UK. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2016.12.011DOI Listing
June 2017

Longitudinal differences in white matter integrity in youth at high familial risk for bipolar disorder.

Bipolar Disord 2017 05 3;19(3):158-167. Epub 2017 May 3.

Institut universitaire en santé mentale de Québec, Québec City, Québec, Canada.

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http://dx.doi.org/10.1111/bdi.12489DOI Listing
May 2017

An examination of the language construct in NIMH's research domain criteria: Time for reconceptualization!

Am J Med Genet B Neuropsychiatr Genet 2016 09 10;171(6):904-19. Epub 2016 Mar 10.

Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025728PMC
http://dx.doi.org/10.1002/ajmg.b.32438DOI Listing
September 2016

Information processing speed mediates the relationship between white matter and general intelligence in schizophrenia.

Psychiatry Res Neuroimaging 2016 Aug 6;254:26-33. Epub 2016 Jun 6.

Division of Psychiatry, University of Edinburgh, Edinburgh, UK; Scottish Imaging Network: A Platform for Scientific Excellence (SINAPSE) Collaboration, Edinburgh, UK; Centre for Clinical Brain Sciences, Western General Hospital, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1016/j.pscychresns.2016.05.008DOI Listing
August 2016

Negative symptoms and longitudinal grey matter tissue loss in adolescents at risk of psychosis: preliminary findings from a 6-year follow-up study.

Br J Psychiatry 2016 06 3;208(6):565-70. Epub 2015 Dec 3.

Andrew G. McKechanie, MRCPsych, The Patrick Wild Centre, The University of Edinburgh, Edinburgh; Thomas W. J. Moorhead, PhD, Division of Psychiatry, The University of Edinburgh, Edinburgh; Andrew C. Stanfield, PhD, MRCPsych, The Patrick Wild Centre, The University of Edinburgh, Edinburgh; Heather C. Whalley, PhD, Eve C. Johnstone, MD, FRCP, FRCPsych, Stephen M. Lawrie, MD, FRCPE, FRCPsych, David G. C. Owens, MD, FRCP, FRCPsych, Division of Psychiatry, The University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1192/bjp.bp.114.154526DOI Listing
June 2016

White matter integrity and its association with affective and interpersonal symptoms in borderline personality disorder.

Neuroimage Clin 2015 7;7:476-81. Epub 2015 Feb 7.

Division of Psychiatry, University of Edinburgh, Edinburgh, UK ; Neuroscience and Mental Health Research Institute, Cardiff University, Hadyn Ellis Building, Maindy Road, Cardiff, UK.

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http://dx.doi.org/10.1016/j.nicl.2015.01.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325126PMC
September 2015

Cortical Surface Area Differentiates Familial High Risk Individuals Who Go on to Develop Schizophrenia.

Biol Psychiatry 2015 Sep 7;78(6):413-20. Epub 2015 Feb 7.

Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1016/j.biopsych.2014.12.030DOI Listing
September 2015

Cortical Thickness in Individuals at High Familial Risk of Mood Disorders as They Develop Major Depressive Disorder.

Biol Psychiatry 2015 Jul 30;78(1):58-66. Epub 2014 Oct 30.

Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1016/j.biopsych.2014.10.018DOI Listing
July 2015

Hippocampal, amygdala and nucleus accumbens volume in first-episode schizophrenia patients and individuals at high familial risk: A cross-sectional comparison.

Schizophr Res 2015 Jun 10;165(1):45-51. Epub 2015 Apr 10.

Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK.

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http://dx.doi.org/10.1016/j.schres.2015.03.024DOI Listing
June 2015

The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data.

Authors:
Paul M Thompson Jason L Stein Sarah E Medland Derrek P Hibar Alejandro Arias Vasquez Miguel E Renteria Roberto Toro Neda Jahanshad Gunter Schumann Barbara Franke Margaret J Wright Nicholas G Martin Ingrid Agartz Martin Alda Saud Alhusaini Laura Almasy Jorge Almeida Kathryn Alpert Nancy C Andreasen Ole A Andreassen Liana G Apostolova Katja Appel Nicola J Armstrong Benjamin Aribisala Mark E Bastin Michael Bauer Carrie E Bearden Orjan Bergmann Elisabeth B Binder John Blangero Henry J Bockholt Erlend Bøen Catherine Bois Dorret I Boomsma Tom Booth Ian J Bowman Janita Bralten Rachel M Brouwer Han G Brunner David G Brohawn Randy L Buckner Jan Buitelaar Kazima Bulayeva Juan R Bustillo Vince D Calhoun Dara M Cannon Rita M Cantor Melanie A Carless Xavier Caseras Gianpiero L Cavalleri M Mallar Chakravarty Kiki D Chang Christopher R K Ching Andrea Christoforou Sven Cichon Vincent P Clark Patricia Conrod Giovanni Coppola Benedicto Crespo-Facorro Joanne E Curran Michael Czisch Ian J Deary Eco J C de Geus Anouk den Braber Giuseppe Delvecchio Chantal Depondt Lieuwe de Haan Greig I de Zubicaray Danai Dima Rali Dimitrova Srdjan Djurovic Hongwei Dong Gary Donohoe Ravindranath Duggirala Thomas D Dyer Stefan Ehrlich Carl Johan Ekman Torbjørn Elvsåshagen Louise Emsell Susanne Erk Thomas Espeseth Jesen Fagerness Scott Fears Iryna Fedko Guillén Fernández Simon E Fisher Tatiana Foroud Peter T Fox Clyde Francks Sophia Frangou Eva Maria Frey Thomas Frodl Vincent Frouin Hugh Garavan Sudheer Giddaluru David C Glahn Beata Godlewska Rita Z Goldstein Randy L Gollub Hans J Grabe Oliver Grimm Oliver Gruber Tulio Guadalupe Raquel E Gur Ruben C Gur Harald H H Göring Saskia Hagenaars Tomas Hajek Geoffrey B Hall Jeremy Hall John Hardy Catharina A Hartman Johanna Hass Sean N Hatton Unn K Haukvik Katrin Hegenscheid Andreas Heinz Ian B Hickie Beng-Choon Ho David Hoehn Pieter J Hoekstra Marisa Hollinshead Avram J Holmes Georg Homuth Martine Hoogman L Elliot Hong Norbert Hosten Jouke-Jan Hottenga Hilleke E Hulshoff Pol Kristy S Hwang Clifford R Jack Mark Jenkinson Caroline Johnston Erik G Jönsson René S Kahn Dalia Kasperaviciute Sinead Kelly Sungeun Kim Peter Kochunov Laura Koenders Bernd Krämer John B J Kwok Jim Lagopoulos Gonzalo Laje Mikael Landen Bennett A Landman John Lauriello Stephen M Lawrie Phil H Lee Stephanie Le Hellard Herve Lemaître Cassandra D Leonardo Chiang-Shan Li Benny Liberg David C Liewald Xinmin Liu Lorna M Lopez Eva Loth Anbarasu Lourdusamy Michelle Luciano Fabio Macciardi Marise W J Machielsen Glenda M Macqueen Ulrik F Malt René Mandl Dara S Manoach Jean-Luc Martinot Mar Matarin Karen A Mather Manuel Mattheisen Morten Mattingsdal Andreas Meyer-Lindenberg Colm McDonald Andrew M McIntosh Francis J McMahon Katie L McMahon Eva Meisenzahl Ingrid Melle Yuri Milaneschi Sebastian Mohnke Grant W Montgomery Derek W Morris Eric K Moses Bryon A Mueller Susana Muñoz Maniega Thomas W Mühleisen Bertram Müller-Myhsok Benson Mwangi Matthias Nauck Kwangsik Nho Thomas E Nichols Lars-Göran Nilsson Allison C Nugent Lars Nyberg Rene L Olvera Jaap Oosterlaan Roel A Ophoff Massimo Pandolfo Melina Papalampropoulou-Tsiridou Martina Papmeyer Tomas Paus Zdenka Pausova Godfrey D Pearlson Brenda W Penninx Charles P Peterson Andrea Pfennig Mary Phillips G Bruce Pike Jean-Baptiste Poline Steven G Potkin Benno Pütz Adaikalavan Ramasamy Jerod Rasmussen Marcella Rietschel Mark Rijpkema Shannon L Risacher Joshua L Roffman Roberto Roiz-Santiañez Nina Romanczuk-Seiferth Emma J Rose Natalie A Royle Dan Rujescu Mina Ryten Perminder S Sachdev Alireza Salami Theodore D Satterthwaite Jonathan Savitz Andrew J Saykin Cathy Scanlon Lianne Schmaal Hugo G Schnack Andrew J Schork S Charles Schulz Remmelt Schür Larry Seidman Li Shen Jody M Shoemaker Andrew Simmons Sanjay M Sisodiya Colin Smith Jordan W Smoller Jair C Soares Scott R Sponheim Emma Sprooten John M Starr Vidar M Steen Stephen Strakowski Lachlan Strike Jessika Sussmann Philipp G Sämann Alexander Teumer Arthur W Toga Diana Tordesillas-Gutierrez Daniah Trabzuni Sarah Trost Jessica Turner Martijn Van den Heuvel Nic J van der Wee Kristel van Eijk Theo G M van Erp Neeltje E M van Haren Dennis van 't Ent Marie-Jose van Tol Maria C Valdés Hernández Dick J Veltman Amelia Versace Henry Völzke Robert Walker Henrik Walter Lei Wang Joanna M Wardlaw Michael E Weale Michael W Weiner Wei Wen Lars T Westlye Heather C Whalley Christopher D Whelan Tonya White Anderson M Winkler Katharina Wittfeld Girma Woldehawariat Christiane Wolf David Zilles Marcel P Zwiers Anbupalam Thalamuthu Peter R Schofield Nelson B Freimer Natalia S Lawrence Wayne Drevets

Brain Imaging Behav 2014 Jun;8(2):153-82

Imaging Genetics Center, Institute for Neuroimaging and Informatics, Keck School of Medicine, University of Southern California, 2001 N. Soto Street, Los Angeles, CA, 90033, USA,

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http://dx.doi.org/10.1007/s11682-013-9269-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008818PMC
June 2014

Altered amygdala connectivity within the social brain in schizophrenia.

Schizophr Bull 2014 Jan 12;40(1):152-60. Epub 2013 Jul 12.

*To whom correspondence should be addressed; Department of Psychology, Stony Brook University, Stony Brook, NY 11794-2500, US; tel: 773-916-7662, fax: 631-632-7876, e-mail:

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http://dx.doi.org/10.1093/schbul/sbt086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885300PMC
January 2014

Cortical thickness in first-episode schizophrenia patients and individuals at high familial risk: a cross-sectional comparison.

Schizophr Res 2013 Dec 10;151(1-3):259-64. Epub 2013 Oct 10.

Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, United Kingdom; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA; Olin Neuropsychiatry Center, Institute of Living, Hartford Hospital, Hartford, CT, USA.

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http://dx.doi.org/10.1016/j.schres.2013.09.024DOI Listing
December 2013

White matter integrity as an intermediate phenotype: exploratory genome-wide association analysis in individuals at high risk of bipolar disorder.

Psychiatry Res 2013 Apr 4;206(2-3):223-31. Epub 2012 Dec 4.

Division of Psychiatry, University of Edinburgh, Kennedy Tower, Royal Edinburgh Hospital, Morningside Park, Edinburgh EH10 5HF, UK.

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http://dx.doi.org/10.1016/j.psychres.2012.11.002DOI Listing
April 2013

Medial temporal lobe function during emotional memory in early Alzheimer's disease, mild cognitive impairment and healthy ageing: an fMRI study.

BMC Psychiatry 2013 Mar 6;13:76. Epub 2013 Mar 6.

Scottish Dementia Clinical Research Network, Human Cognitive Neuroscience and Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh EH8 9JZ, UK.

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http://dx.doi.org/10.1186/1471-244X-13-76DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599533PMC
March 2013

Progress in imaging the effects of psychosis susceptibility gene variants.

Expert Rev Neurother 2013 Jan;13(1):37-47

Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, EH10 5HF, UK.

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http://dx.doi.org/10.1586/ern.12.145DOI Listing
January 2013

Relationship between gyrification and functional connectivity of the prefrontal cortex in subjects at high genetic risk of schizophrenia.

Curr Pharm Des 2012 ;18(4):434-42

Division of Psychiatry, School of Molecular and Clinical Medicine, University of Edinburgh, Edinburgh, Scotland, UK.

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http://dx.doi.org/10.2174/138161212799316235DOI Listing
October 2012

Review of functional magnetic resonance imaging studies comparing bipolar disorder and schizophrenia.

Bipolar Disord 2012 Jun;14(4):411-31

Division of Psychiatry, School of Molecular and Clinical Medicine, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1111/j.1399-5618.2012.01016.xDOI Listing
June 2012

Effects of a mis-sense DISC1 variant on brain activation in two cohorts at high risk of bipolar disorder or schizophrenia.

Am J Med Genet B Neuropsychiatr Genet 2012 Apr 15;159B(3):343-53. Epub 2012 Feb 15.

Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK.

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http://doi.wiley.com/10.1002/ajmg.b.32035
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http://dx.doi.org/10.1002/ajmg.b.32035DOI Listing
April 2012

A systematic review and meta-analysis of the fMRI investigation of autism spectrum disorders.

Neurosci Biobehav Rev 2012 Feb 11;36(2):901-42. Epub 2011 Nov 11.

Division of Psychiatry, University of Edinburgh, Kennedy Tower, Royal Edinburgh Hospital, Edinburgh, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S014976341100201
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http://dx.doi.org/10.1016/j.neubiorev.2011.10.008DOI Listing
February 2012

Genetic variation in CNTNAP2 alters brain function during linguistic processing in healthy individuals.

Am J Med Genet B Neuropsychiatr Genet 2011 Dec 10;156B(8):941-8. Epub 2011 Oct 10.

Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK.

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http://dx.doi.org/10.1002/ajmg.b.31241DOI Listing
December 2011

Impact of cannabis use on thalamic volume in people at familial high risk of schizophrenia.

Br J Psychiatry 2011 Nov 8;199(5):386-90. Epub 2011 Sep 8.

Robert Ferguson Unit, Astley Ainslee Hospital, Edinburgh and Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh EH10 5HF, UK.

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http://dx.doi.org/10.1192/bjp.bp.110.090175DOI Listing
November 2011

The impact of substance use on brain structure in people at high risk of developing schizophrenia.

Schizophr Bull 2011 Sep 11;37(5):1066-76. Epub 2010 Mar 11.

Division of Psychiatry, School of Molecular and Clinical Medicine, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh EH10 5HF, UK.

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http://dx.doi.org/10.1093/schbul/sbq013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160229PMC
September 2011

The neural basis of familial risk and temperamental variation in individuals at high risk of bipolar disorder.

Biol Psychiatry 2011 Aug 24;70(4):343-9. Epub 2011 May 24.

Division of Psychiatry, School of Molecular and Clinical Medicine, University of Edinburgh, Edinburgh, Scotland, United Kingdom.

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http://dx.doi.org/10.1016/j.biopsych.2011.04.007DOI Listing
August 2011

Longitudinal volume reductions in people at high genetic risk of schizophrenia as they develop psychosis.

Biol Psychiatry 2011 May 17;69(10):953-8. Epub 2010 Dec 17.

Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1016/j.biopsych.2010.11.003DOI Listing
May 2011

Effects of the BDNF Val66Met polymorphism on neural responses to facial emotion.

Psychiatry Res 2011 Mar 18;191(3):182-8. Epub 2011 Feb 18.

Division of Psychiatry, University of Edinburg, Edinburg, United Kingdom.

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http://dx.doi.org/10.1016/j.pscychresns.2010.10.001DOI Listing
March 2011

Effects of the BDNF val66met polymorphism on prefrontal brain function in a population at high genetic risk of schizophrenia.

Am J Med Genet B Neuropsychiatr Genet 2010 Dec 18;153B(8):1474-82. Epub 2010 Oct 18.

Division of Psychiatry, Royal Edinburgh Hospital, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1002/ajmg.b.31128DOI Listing
December 2010

Functional magnetic resonance imaging of BDNF val66met polymorphism in unmedicated subjects at high genetic risk of schizophrenia performing a verbal memory task.

Psychiatry Res 2010 Sep 13;183(3):195-201. Epub 2010 Aug 13.

Division of Psychiatry, University of Edinburgh, Kennedy Tower, Royal Edinburgh Hospital, Morningside Park, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1016/j.pscychresns.2010.06.009DOI Listing
September 2010

Functional imaging of emotional memory in bipolar disorder and schizophrenia.

Bipolar Disord 2009 Dec;11(8):840-56

Division of Psychiatry, School of Molecular and Clinical Medicine, University of Edinburgh, Edinburgh, Scotland, UK.

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http://dx.doi.org/10.1111/j.1399-5618.2009.00768.xDOI Listing
December 2009

Prefrontal function and activation in bipolar disorder and schizophrenia.

Am J Psychiatry 2008 Mar 15;165(3):378-84. Epub 2008 Jan 15.

Division of Psychiatry, University of Edinburgh, Kennedy Tower, Royal Edinburgh Hospital, Edinburgh, UK.

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http://psychiatryonline.org/doi/abs/10.1176/appi.ajp.2007.07
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http://dx.doi.org/10.1176/appi.ajp.2007.07020365DOI Listing
March 2008

The neurobiological underpinnings of risk and conversion in relatives of patients with schizophrenia.

Int Rev Psychiatry 2007 Aug;19(4):383-97

Division of Psychiatry, University of Edinburgh, Scotland, UK.

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http://www.tandfonline.com/doi/full/10.1080/0954026070149686
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http://dx.doi.org/10.1080/09540260701496869DOI Listing
August 2007

A neuregulin 1 variant associated with abnormal cortical function and psychotic symptoms.

Nat Neurosci 2006 Dec 29;9(12):1477-8. Epub 2006 Oct 29.

Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Morningside Park, Edinburgh, EH10 5HF, UK.

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http://dx.doi.org/10.1038/nn1795DOI Listing
December 2006

Grey matter changes can improve the prediction of schizophrenia in subjects at high risk.

BMC Med 2006 Dec 7;4:29. Epub 2006 Dec 7.

Division of Psychiatry, School of Molecular and Clinical Medicine, The University of Edinburgh, The Royal Edinburgh Hospital, Morningside Park, Edinburgh, Scotland, EH10 5HF, UK.

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http://dx.doi.org/10.1186/1741-7015-4-29DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1698489PMC
December 2006

Parcellating the temporal lobes from magnetic resonance images using generic software in subjects at high risk of developing schizophrenia.

Psychiatry Res 2006 Oct 1;147(2-3):197-212. Epub 2006 Aug 1.

Division of Psychiatry, University of Edinburgh, Kennedy Tower, Royal Edinburgh Hospital, Morningside Park, Edinburgh EH10 5HF, UK.

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http://dx.doi.org/10.1016/j.pscychresns.2006.01.012DOI Listing
October 2006

Functional imaging as a predictor of schizophrenia.

Biol Psychiatry 2006 Sep 7;60(5):454-62. Epub 2006 Feb 7.

Division of Psychiatry, University of Edinburgh, Edinburgh, Scotland, UK.

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http://dx.doi.org/10.1016/j.biopsych.2005.11.013DOI Listing
September 2006

A visual joke fMRI investigation into Theory of Mind and enhanced risk of schizophrenia.

Neuroimage 2006 Jul 19;31(4):1850-8. Epub 2006 Apr 19.

University of Edinburgh, Division of Psychiatry, Kennedy Tower, Royal Edinburgh Hospital, Morningside Park, Edinburgh EH10 5HF, UK.

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http://dx.doi.org/10.1016/j.neuroimage.2006.02.011DOI Listing
July 2006

Genetic liability to schizophrenia or bipolar disorder and its relationship to brain structure.

Am J Med Genet B Neuropsychiatr Genet 2006 Jan;141B(1):76-83

Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh EH 10 5HF, United Kingdom.

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http://dx.doi.org/10.1002/ajmg.b.30254DOI Listing
January 2006

Empirical comparison of maximal voxel and non-isotropic adjusted cluster extent results in a voxel-based morphometry study of comorbid learning disability with schizophrenia.

Neuroimage 2005 Nov 8;28(3):544-52. Epub 2005 Aug 8.

Division of Psychiatry, Image Analysis Laboratory, University of Edinburgh, Royal Edinburgh Hospital, Morningside Park, Edinburgh EH10 5HF, Scotland UK.

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http://linkinghub.elsevier.com/retrieve/pii/S105381190500432
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http://dx.doi.org/10.1016/j.neuroimage.2005.04.045DOI Listing
November 2005

Functional disconnectivity in subjects at high genetic risk of schizophrenia.

Brain 2005 Sep 1;128(Pt 9):2097-108. Epub 2005 Jun 1.

Division of Psychiatry, School of Informatics, University of Edinburgh, Edinburgh, Scotland.

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http://dx.doi.org/10.1093/brain/awh556DOI Listing
September 2005

Neural correlates of enhanced genetic risk for schizophrenia.

Neuroscientist 2005 Jun;11(3):238-49

Division of Psychiatry, University of Edinburgh, Edinburgh, Scotland.

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http://dx.doi.org/10.1177/1073858404274111DOI Listing
June 2005

Grey matter changes over time in high risk subjects developing schizophrenia.

Neuroimage 2005 May;25(4):1023-30

Division of Psychiatry, University of Edinburgh, The Royal Edinburgh Hospital, Morningside Park, Edinburgh EH10 5HF, Scotland, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S105381190500018
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http://dx.doi.org/10.1016/j.neuroimage.2005.01.006DOI Listing
May 2005

Voxel-based morphometry of comorbid schizophrenia and learning disability: analyses in normalized and native spaces using parametric and nonparametric statistical methods.

Neuroimage 2004 May;22(1):188-202

Image Analysis Laboratory, Division of Psychiatry, Royal Edinburgh Hospital, University of Edinburgh, Edinburgh EH10 5HF, Scotland, UK.

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http://dx.doi.org/10.1016/j.neuroimage.2003.12.012DOI Listing
May 2004

Voxel-based morphometry of grey matter densities in subjects at high risk of schizophrenia.

Schizophr Res 2003 Nov;64(1):1-13

Department of Psychiatry, University of Edinburgh, Kennedy Tower, Royal Edinburgh Hospital, Morningside Park, Edinburgh EH10 5HF, Scotland, UK.

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http://dx.doi.org/10.1016/s0920-9964(03)00158-0DOI Listing
November 2003

Structural and functional abnormalities of the amygdala in schizophrenia.

Ann N Y Acad Sci 2003 Apr;985:445-60

Edinburgh University, Department of Psychiatry, Kennedy Tower, Royal Edinburgh Hospital, Edinburgh, Scotland, UK.

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http://dx.doi.org/10.1111/j.1749-6632.2003.tb07099.xDOI Listing
April 2003

Neuropsychology, genetic liability, and psychotic symptoms in those at high risk of schizophrenia.

J Abnorm Psychol 2003 Feb;112(1):38-48

University Department of Psychiatry, University of Edinburgh, Scotland.

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February 2003

Structural gray matter differences between first-episode schizophrenics and normal controls using voxel-based morphometry.

Neuroimage 2002 Oct;17(2):880-9

Department of Psychiatry, University of Edinburgh, Kennedy Tower, Royal Edinburgh Hospital, Morningside Park, Edinburgh EH10 5HF, Scotland, United Kingdom.

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October 2002

Temporal lobe volume changes in people at high risk of schizophrenia with psychotic symptoms.

Br J Psychiatry 2002 Aug;181:138-43

University Department of Psychiatry, Royal Edinburgh Hospital, Edinburgh, UK.

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http://dx.doi.org/10.1017/s0007125000161860DOI Listing
August 2002

Reduced frontotemporal functional connectivity in schizophrenia associated with auditory hallucinations.

Biol Psychiatry 2002 Jun;51(12):1008-11

University Department of Psychiatry, Royal Edinburgh Hospital, Morningside Park, Edinburgh, Scotland, UK.

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http://dx.doi.org/10.1016/s0006-3223(02)01316-1DOI Listing
June 2002