Publications by authors named "Hayley Whitaker"

64Publications

A Modified Newcastle-Ottawa Scale for Assessment of Study Quality in Genetic Urological Research.

Eur Urol 2020 Dec 26. Epub 2020 Dec 26.

UCL Division of Surgery & Interventional Science, University College London, London, UK; Department of Urology, University College London Hospitals NHS Foundation Trust, London, UK.

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December 2020

Prostate Cancer Undetected by mpMRI: Tumor Conspicuity is Reliant Upon Optimal Scan Timing and Quality.

Urology 2020 Dec 2. Epub 2020 Dec 2.

UCL Division of Surgery & Interventional Science, University College London, London, UK; Department of Urology, University College London Hospitals NHS Foundation Trust, London, UK.

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December 2020

Author Correction: Genetic alterations in the 3q26.31-32 locus confer an aggressive prostate cancer phenotype.

Commun Biol 2020 Oct 8;3(1):570. Epub 2020 Oct 8.

Molecular Diagnostics and Therapeutics Group, Research Department of Targeted Intervention, Division of Surgery & Interventional Science, University College London, London, UK.

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October 2020

Conspicuity of prostate cancer on multiparametric magnetic resonance imaging: A cross-disciplinary translational hypothesis.

FASEB J 2020 Nov 13;34(11):14150-14159. Epub 2020 Sep 13.

UCL Division of Surgery & Interventional Science, University College London, London, UK.

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November 2020

Genetic alterations in the 3q26.31-32 locus confer an aggressive prostate cancer phenotype.

Commun Biol 2020 Aug 14;3(1):440. Epub 2020 Aug 14.

Molecular Diagnostics and Therapeutics Group, Research Department of Targeted Intervention, Division of Surgery & Interventional Science, University College London, London, UK.

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August 2020

Prostate cancer biology & genomics.

Transl Androl Urol 2020 Jun;9(3):1481-1491

Division of Surgical and Interventional Sciences, Faculty of Medicine, University College London, London, UK.

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June 2020

Five-year Outcomes of Magnetic Resonance Imaging-based Active Surveillance for Prostate Cancer: A Large Cohort Study.

Eur Urol 2020 Sep 30;78(3):443-451. Epub 2020 Apr 30.

Division of Surgery and Interventional Science, University College London, London, UK; Department of Urology, UCLH NHS Foundation Trust, London, UK.

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September 2020

PIM kinase inhibition: co-targeted therapeutic approaches in prostate cancer.

Signal Transduct Target Ther 2020 Jan 31;5(1). Epub 2020 Jan 31.

Molecular Diagnostics and Therapeutics Group, University College London, London, UK.

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January 2020

An optimised saliva collection method to produce high-yield, high-quality RNA for translational research.

PLoS One 2020 9;15(3):e0229791. Epub 2020 Mar 9.

Gastroenterological Intervention Centre (GENIE) and Molecular Diagnostics and Therapeutics Group, University College London, London, England, United Kingdom.

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July 2020

Stroma in normal and cancer wound healing.

FEBS J 2019 08 15;286(15):2909-2920. Epub 2019 Apr 15.

Molecular Diagnostics and Therapeutics Group, Charles Bell House, Division of Surgery and Interventional Science, University College London, UK.

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August 2019

VERDICT MRI for Prostate Cancer: Intracellular Volume Fraction versus Apparent Diffusion Coefficient.

Radiology 2019 05 2;291(2):391-397. Epub 2019 Apr 2.

From the UCL Centre for Medical Imaging, University College London, 2nd Floor Charles Bell House, 43-45 Foley Street, London W1W 7TS, England (E.W.J., E.B.C., H.S.S., J.O., M.B.A., D. Atkinson, S.P.); UCL Centre for Medical Image Computing, London, England (E.B.C., U.F., B.Y., S.O., D.H., D. Alexander, E.P.); UCL Centre for Molecular Intervention, London, England (H.P., S.H., H.W.); Department of Histopathology, University College Hospital, London, England (D.P., M.R.J., A.F.); Department of Radiology (J.C.) and Centre for Medical Imaging (J.C., W.P., A.S.), University College Hospital, London, England; Division of Surgery and Interventional Science, Faculty of Medical Sciences, University College London, London, England (F.G., A.G., C.M.M., M.E.); and Department of Surgery and Cancer, Imperial College London, London, England (H.U.A.).

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May 2019

Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets.

Nat Genet 2018 05 16;50(5):682-692. Epub 2018 Apr 16.

The Institute of Cancer Research, London, UK.

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May 2018

Asporin is a stromally expressed marker associated with prostate cancer progression.

Br J Cancer 2017 Mar 2;116(6):775-784. Epub 2017 Feb 2.

Department of Surgery, Division of Urology, McGill University and the Cancer Research Program of the Research Institute of McGill University Health Centre, Montreal, Quebec H4A 3J1, Canada.

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March 2017

Whole blood mRNA in prostate cancer reveals a four-gene androgen regulated panel.

Endocr Relat Cancer 2016 10 30;23(10):797-812. Epub 2016 Aug 30.

Uro-Oncology Research GroupCancer Research UK Cambridge Institute, Robinson Way, Cambridge, UK Biomarker InitiativeCancer Research UK Cambridge Institute, Robinson Way, Cambridge, UK Molecular Diagnostics and Therapeutics GroupUniversity College London, London, UK

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October 2016

The Early Effects of Rapid Androgen Deprivation on Human Prostate Cancer.

Eur Urol 2016 08 10;70(2):214-8. Epub 2015 Nov 10.

Cancer Research UK Cambridge Institute, Li Ka Shing Centre, Cambridge, UK; Department of Urology, Cambridge University Hospitals NHS Trust, Cambridge, UK; Nuffield Department of Surgery, University of Oxford, John Radcliffe Hospital, Headington, Oxford, UK.

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August 2016

HES5 silencing is an early and recurrent change in prostate tumourigenesis.

Endocr Relat Cancer 2015 Apr 5;22(2):131-44. Epub 2015 Jan 5.

Cancer Research UK Cambridge InstituteUniversity of Cambridge, Cambridge, CB2 0RE, UKDivision of Genetics and EpidemiologyThe Institute of Cancer Research, Sutton, UKDepartment of Biological Sciences and School of MedicineUniversity of East Anglia, Norwich, UKRoyal Marsden NHS Foundation TrustLondon and Sutton, UKDepartments of PathologyUrologySurgical OncologyAddenbrooke's Hospital, Hills Road, Cambridge, UK

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April 2015

Regulation of the localisation and function of the oncogene LYRIC/AEG-1 by ubiquitination at K486 and K491.

Mol Oncol 2014 May 24;8(3):633-41. Epub 2014 Jan 24.

Uro-Oncology Research Group, Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK. Electronic address:

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May 2014

Prognostic and therapeutic impact of argininosuccinate synthetase 1 control in bladder cancer as monitored longitudinally by PET imaging.

Cancer Res 2014 Feb 27;74(3):896-907. Epub 2013 Nov 27.

Authors' Affiliations: Barts Cancer Institute-a Cancer Research UK Center of Excellence, John Vane Science Center, Queen Mary University of London; Department of Medicine, Imperial College, Charing Cross Campus; St Bartholomew's Hospital, Barts Health NHS Trust, West Smithfield, London; Wellcome Trust Center for Human Genetics, Oxford; Cancer Research UK Cambridge Research Institute, Li Ka Shing Center; Hutchison/MRC Research Center, University of Cambridge, Medical Research Council Cancer Unit; Pharmacometrics Ltd., Cambridge; Dundee Cancer Center, University of Dundee, Ninewells Hospital, Dundee, United Kingdom; Laboratory of Cancer Genetics and Translational Oncology, S Croce General Hospital, Cuneo, Italy; Department of Structural Biology, Medical University of Lodz, Lodz, Poland; Polaris Group, San Diego, California; Department of Pathology, Chi-Mei Medical Center; Department of Biotechnology, Southern Taiwan University of Science and Technology, Tainan, Taiwan; and National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan.

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February 2014

Role of the HSP90-associated cochaperone p23 in enhancing activity of the androgen receptor and significance for prostate cancer.

Mol Endocrinol 2012 Oct 16;26(10):1694-706. Epub 2012 Aug 16.

Androgen Signaling Laboratory, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, United Kingdom.

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October 2012

Method for sampling tissue for research which preserves pathological data in radical prostatectomy.

Prostate 2013 Jan 16;73(2):194-202. Epub 2012 Jul 16.

Department of Histopathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge Biomedical Campus, Cambridge, UK.

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January 2013

RAS pathways in prostate cancer - mediators of hormone resistance?

Curr Cancer Drug Targets 2010 Dec;10(8):834-9

Uro-Oncology Research Group, Cancer Research UK Cambridge Research Institute, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK.

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December 2010

The potential value of microseminoprotein-beta as a prostate cancer biomarker and therapeutic target.

Prostate 2010 Feb;70(3):333-40

Uro-Oncology Research Group, CRUK Cambridge Research Institute, Li Ka Shing Centre, Robinson Way, Cambridge, UK.

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February 2010

Alterations in beta-catenin expression and localization in prostate cancer.

Prostate 2008 Aug;68(11):1196-205

Uro-Oncology Research Group, Cancer Research UK Cambridge Research Institute, Li Ka Shing Centre, Robinson Way, Cambridge, UK.

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August 2008

Structural basis for the nuclear import of the human androgen receptor.

J Cell Sci 2008 Apr 4;121(Pt 7):957-68. Epub 2008 Mar 4.

Uro-Oncology Research Group, Cancer Research UK Cambridge Research Institute, Robinson Way, Cambridge, CB2 0RE, UK.

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April 2008

Labeling and identification of LNCaP cell surface proteins: a pilot study.

Prostate 2007 Jun;67(9):943-54

Uro-Oncology Research Group, CRUK Cambridge Research Institute, Li Ka Shing Centre, Robinson Way, Cambridge, UK.

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June 2007

Androgen receptor is targeted to distinct subcellular compartments in response to different therapeutic antiandrogens.

Clin Cancer Res 2004 Nov;10(21):7392-401

Prostate Cancer Research Group, Department of Cancer Medicine, Faculty of Medicine, Imperial College London, London, United Kingdom.

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November 2004