Hayato Fujita

Hayato Fujita

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Hayato Fujita

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Quantitative evaluation of the intratumoral distribution of platinum in oxaliplatin-treated rectal cancer: In situ visualization of platinum via synchrotron radiation X-ray fluorescence spectrometry.

Authors:
Ryo Koba Hayato Fujita Maiko Nishibori Kiyoshi Saeki Kinuko Nagayoshi Yoshihiko Sadakari Shuntaro Nagai Oki Sekizawa Kiyofumi Nitta Tatsuya Manabe Takashi Ueki Tatsuhiro Ishida Yoshinao Oda Masafumi Nakamura

Int J Cancer 2019 Jul 25. Epub 2019 Jul 25.

Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1002/ijc.32592DOI Listing
July 2019

Application of ultrasonography to high-tie and low-tie vascular ligation of the inferior mesenteric artery in laparoscopic colorectal cancer surgery: technical notes.

Authors:
Yoshihiko Sadakari Shuntaro Nagai Vittoria Vanessa Velasquez Kinuko Nagayoshi Hayato Fujita Kenoki Ohuchida Tatsuya Manabe Takao Ohtsuka Masafumi Nakamura

Surg Endosc 2019 01 25;33(1):309-314. Epub 2018 Jun 25.

Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.

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http://dx.doi.org/10.1007/s00464-018-6302-1DOI Listing
January 2019

Laparoscopic excision of neurogenic retrorectal tumors.

Authors:
Tatsuya Manabe Ryo Koba Kinuko Nagayoshi Yoshihiko Sadakari Hayato Fujita Shuntaro Nagai Takashi Ueki Eishi Nagai Masafumi Nakamura

Asian J Endosc Surg 2017 May;10(2):223-226

Department of Surgery and Oncology, Graduate School of Medicine, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1111/ases.12337DOI Listing
May 2017

IgG4-related sclerosing mesenteritis causing bowel obstruction: a case report.

Authors:
Atsushi Abe Tatsuya Manabe Nobuyoshi Takizawa Takashi Ueki Daisuke Yamada Kinuko Nagayoshi Yoshihiko Sadakari Hayato Fujita Shuntaro Nagai Hidetaka Yamamoto Yoshinao Oda Masafumi Nakamura

Surg Case Rep 2016 Dec 30;2(1):120. Epub 2016 Oct 30.

Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka, 812-8582, Japan.

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http://dx.doi.org/10.1186/s40792-016-0248-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086477PMC
December 2016

Calpain inhibitor calpeptin suppresses pancreatic cancer by disrupting cancer-stromal interactions in a mouse xenograft model.

Authors:
Masaki Yoshida Yoshihiro Miyasaka Kenoki Ohuchida Takashi Okumura Biao Zheng Nobuhiro Torata Hayato Fujita Toshinaga Nabae Tatsuya Manabe Masaya Shimamoto Takao Ohtsuka Kazuhiro Mizumoto Masafumi Nakamura

Cancer Sci 2016 Oct 24;107(10):1443-1452. Epub 2016 Sep 24.

Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1111/cas.13024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084662PMC
October 2016

Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms.

Authors:
Momoko Horikoshi Lorenzo Pasquali Steven Wiltshire Jeroen R Huyghe Anubha Mahajan Jennifer L Asimit Teresa Ferreira Adam E Locke Neil R Robertson Xu Wang Xueling Sim Hayato Fujita Kazuo Hara Robin Young Weihua Zhang Sungkyoung Choi Han Chen Ismeet Kaur Fumihiko Takeuchi Pierre Fontanillas Dorothée Thuillier Loic Yengo Jennifer E Below Claudia H T Tam Ying Wu Gonçalo Abecasis David Altshuler Graeme I Bell John Blangero Noél P Burtt Ravindranath Duggirala Jose C Florez Craig L Hanis Mark Seielstad Gil Atzmon Juliana C N Chan Ronald C W Ma Philippe Froguel James G Wilson Dwaipayan Bharadwaj Josee Dupuis James B Meigs Yoon Shin Cho Taesung Park Jaspal S Kooner John C Chambers Danish Saleheen Takashi Kadowaki E Shyong Tai Karen L Mohlke Nancy J Cox Jorge Ferrer Eleftheria Zeggini Norihiro Kato Yik Ying Teo Michael Boehnke Mark I McCarthy Andrew P Morris

Hum Mol Genet 2016 05 23;25(10):2070-2081. Epub 2016 Feb 23.

Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK, Department of Biostatistics, University of Liverpool, Liverpool, UK

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http://hmg.oxfordjournals.org/content/early/2016/03/07/hmg.d
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http://www.hmg.oxfordjournals.org/lookup/doi/10.1093/hmg/ddw
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http://dx.doi.org/10.1093/hmg/ddw048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062576PMC
May 2016

Suppression of CD51 in pancreatic stellate cells inhibits tumor growth by reducing stroma and altering tumor-stromal interaction in pancreatic cancer.

Authors:
Kohei Horioka Kenoki Ohuchida Masafumi Sada Biao Zheng Taiki Moriyama Hayato Fujita Tatsuya Manabe Takao Ohtsuka Masaya Shimamoto Tetsuyuki Miyazaki Kazuhiro Mizumoto Yoshinao Oda Masafumi Nakamura

Int J Oncol 2016 Apr 3;48(4):1499-508. Epub 2016 Feb 3.

Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.3892/ijo.2016.3374DOI Listing
April 2016

Overexpression of microRNA-5100 decreases the aggressive phenotype of pancreatic cancer cells by targeting PODXL.

Authors:
Yoshiro Chijiiwa Taiki Moriyama Kenoki Ohuchida Toshinaga Nabae Takao Ohtsuka Yoshihiro Miyasaka Hayato Fujita Ryo Maeyama Tatsuya Manabe Atsushi Abe Yusuke Mizuuchi Yoshinao Oda Kazuhiro Mizumoto Masafumi Nakamura

Int J Oncol 2016 Apr 12;48(4):1688-700. Epub 2016 Feb 12.

Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.3892/ijo.2016.3389DOI Listing
April 2016

Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.

Authors:
Minako Imamura Atsushi Takahashi Toshimasa Yamauchi Kazuo Hara Kazuki Yasuda Niels Grarup Wei Zhao Xu Wang Alicia Huerta-Chagoya Cheng Hu Sanghoon Moon Jirong Long Soo Heon Kwak Asif Rasheed Richa Saxena Ronald C W Ma Yukinori Okada Minoru Iwata Jun Hosoe Nobuhiro Shojima Minaka Iwasaki Hayato Fujita Ken Suzuki John Danesh Torben Jørgensen Marit E Jørgensen Daniel R Witte Ivan Brandslund Cramer Christensen Torben Hansen Josep M Mercader Jason Flannick Hortensia Moreno-Macías Noël P Burtt Rong Zhang Young Jin Kim Wei Zheng Jai Rup Singh Claudia H T Tam Hiroshi Hirose Hiroshi Maegawa Chikako Ito Kohei Kaku Hirotaka Watada Yasushi Tanaka Kazuyuki Tobe Ryuzo Kawamori Michiaki Kubo Yoon Shin Cho Juliana C N Chan Dharambir Sanghera Philippe Frossard Kyong Soo Park Xiao-Ou Shu Bong-Jo Kim Jose C Florez Teresa Tusié-Luna Weiping Jia E Shyong Tai Oluf Pedersen Danish Saleheen Shiro Maeda Takashi Kadowaki

Nat Commun 2016 Jan 28;7:10531. Epub 2016 Jan 28.

Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, University of Tokyo, Tokyo 113-0033, Japan.

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http://dx.doi.org/10.1038/ncomms10531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738362PMC
January 2016

Genome-wide association study identifies three novel loci for type 2 diabetes.

Authors:
Kazuo Hara Hayato Fujita Todd A Johnson Toshimasa Yamauchi Kazuki Yasuda Momoko Horikoshi Chen Peng Cheng Hu Ronald C W Ma Minako Imamura Minoru Iwata Tatsuhiko Tsunoda Takashi Morizono Nobuhiro Shojima Wing Yee So Ting Fan Leung Patrick Kwan Rong Zhang Jie Wang Weihui Yu Hiroshi Maegawa Hiroshi Hirose Kohei Kaku Chikako Ito Hirotaka Watada Yasushi Tanaka Kazuyuki Tobe Atsunori Kashiwagi Ryuzo Kawamori Weiping Jia Juliana C N Chan Yik Ying Teo Tai E Shyong Naoyuki Kamatani Michiaki Kubo Shiro Maeda Takashi Kadowaki

Hum Mol Genet 2014 Jan 14;23(1):239-46. Epub 2013 Aug 14.

Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.

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https://academic.oup.com/hmg/article/23/1/239/722387
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http://dx.doi.org/10.1093/hmg/ddt399DOI Listing
January 2014

Apolipoprotein C-II deficiency with no rare variant in the APOC2 gene.

Authors:
Satoru Takase Jun-ichi Osuga Hayato Fujita Kazuo Hara Motohiro Sekiya Masaki Igarashi Mikio Takanashi Yoshinori Takeuchi Yoshihiko Izumida Keisuke Ohta Masayoshi Kumagai Makiko Nishi Midori Kubota Yukari Masuda Yoshino Taira Sachiko Okazaki Yoko Iizuka Naoya Yahagi Ken Ohashi Hiroshi Yoshida Hidekatsu Yanai Norio Tada Takanari Gotoda Shun Ishibashi Takashi Kadowaki Hiroaki Okazaki

J Atheroscler Thromb 2013 7;20(5):481-93. Epub 2013 Mar 7.

Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Japan.

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http://dx.doi.org/10.5551/jat.16592DOI Listing
December 2013

Kindlin-2 expression in peritumoral stroma is associated with poor prognosis in pancreatic ductal adenocarcinoma.

Authors:
Prawej Mahawithitwong Kenoki Ohuchida Naoki Ikenaga Hayato Fujita Ming Zhao Shingo Kozono Koji Shindo Takao Ohtsuka Kazuhiro Mizumoto Masao Tanaka

Pancreas 2013 May;42(4):663-9

Department of Surgery and Oncology, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1097/MPA.0b013e318279bd66DOI Listing
May 2013

Kindlin-1 expression is involved in migration and invasion of pancreatic cancer.

Authors:
Prawej Mahawithitwong Kenoki Ohuchida Naoki Ikenaga Hayato Fujita Ming Zhao Shingo Kozono Koji Shindo Takao Ohtsuka Shinichi Aishima Kazuhiro Mizumoto Masao Tanaka

Int J Oncol 2013 Apr 22;42(4):1360-6. Epub 2013 Feb 22.

Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.3892/ijo.2013.1838DOI Listing
April 2013

Variations with modest effects have an important role in the genetic background of type 2 diabetes and diabetes-related traits.

Authors:
Hayato Fujita Kazuo Hara Nobuhiro Shojima Momoko Horikoshi Minoru Iwata Yushi Hirota Kazuyuki Tobe Susumu Seino Takashi Kadowaki

J Hum Genet 2012 Dec 20;57(12):776-9. Epub 2012 Sep 20.

Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1038/jhg.2012.110DOI Listing
December 2012

Genetic risk score constructed using 14 susceptibility alleles for type 2 diabetes is associated with the early onset of diabetes and may predict the future requirement of insulin injections among Japanese individuals.

Authors:
Minoru Iwata Shiro Maeda Yutaka Kamura Atsuko Takano Hiromi Kato Shihou Murakami Kiyohiro Higuchi Atsushi Takahashi Hayato Fujita Kazuo Hara Takashi Kadowaki Kazuyuki Tobe

Diabetes Care 2012 Aug 11;35(8):1763-70. Epub 2012 Jun 11.

First Department of Internal Medicine, Faculty of Medicine, Toyama University, Toyama, Japan.

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http://dx.doi.org/10.2337/dc11-2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402252PMC
August 2012

Claudin-4 expression predicts survival in pancreatic ductal adenocarcinoma.

Authors:
Kosuke Tsutsumi Norihiro Sato Reiko Tanabe Kazuhiro Mizumoto Katsuya Morimatsu Tadashi Kayashima Hayato Fujita Kenoki Ohuchida Takao Ohtsuka Shunichi Takahata Masafumi Nakamura Masao Tanaka

Ann Surg Oncol 2012 Jul 12;19 Suppl 3:S491-9. Epub 2011 Aug 12.

Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1245/s10434-011-1970-2DOI Listing
July 2012

A single-nucleotide polymorphism in ANK1 is associated with susceptibility to type 2 diabetes in Japanese populations.

Authors:
Minako Imamura Shiro Maeda Toshimasa Yamauchi Kazuo Hara Kazuki Yasuda Takashi Morizono Atsushi Takahashi Momoko Horikoshi Masahiro Nakamura Hayato Fujita Tatsuhiko Tsunoda Michiaki Kubo Hirotaka Watada Hiroshi Maegawa Miki Okada-Iwabu Masato Iwabu Nobuhiro Shojima Toshihiko Ohshige Shintaro Omori Minoru Iwata Hiroshi Hirose Kohei Kaku Chikako Ito Yasushi Tanaka Kazuyuki Tobe Atsunori Kashiwagi Ryuzo Kawamori Masato Kasuga Naoyuki Kamatani Yusuke Nakamura Takashi Kadowaki

Hum Mol Genet 2012 Jul 28;21(13):3042-9. Epub 2012 Mar 28.

Laboratory for Endocrinology and Metabolism, RIKEN Center for Genomic Medicine, Yokohama, Kanagawa, Japan.

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http://hmg.oxfordjournals.org/content/21/13/3042.full.pdf
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http://www.hmg.oxfordjournals.org/cgi/doi/10.1093/hmg/dds113
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http://dx.doi.org/10.1093/hmg/dds113DOI Listing
July 2012

Significance of combination therapy of zoledronic acid and gemcitabine on pancreatic cancer.

Authors:
Ming Zhao Yohei Tominaga Kenoki Ohuchida Kazuhiro Mizumoto Lin Cui Shingo Kozono Hayato Fujita Ryo Maeyama Hiroki Toma Masao Tanaka

Cancer Sci 2012 Jan 7;103(1):58-66. Epub 2011 Nov 7.

Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://doi.wiley.com/10.1111/j.1349-7006.2011.02113.x
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http://dx.doi.org/10.1111/j.1349-7006.2011.02113.xDOI Listing
January 2012

Senescence in intraductal papillary mucinous neoplasm of the pancreas.

Authors:
Yoshihiro Miyasaka Eishi Nagai Kenoki Ohuchida Hayato Fujita Kohei Nakata Akifumi Hayashi Kazuhiro Mizumoto Masazumi Tsuneyoshi Masao Tanaka

Hum Pathol 2011 Dec 5;42(12):2010-7. Epub 2011 Jul 5.

Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan.

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http://dx.doi.org/10.1016/j.humpath.2011.03.007DOI Listing
December 2011

MicroRNA-10b is overexpressed in pancreatic cancer, promotes its invasiveness, and correlates with a poor prognosis.

Authors:
Kohei Nakata Kenoki Ohuchida Kazuhiro Mizumoto Tadashi Kayashima Naoki Ikenaga Hiroshi Sakai Cui Lin Hayato Fujita Takao Otsuka Shinichi Aishima Eishi Nagai Yoshinao Oda Masao Tanaka

Surgery 2011 Nov;150(5):916-22

Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1016/j.surg.2011.06.017DOI Listing
November 2011

MicroRNA expression as a predictive marker for gemcitabine response after surgical resection of pancreatic cancer.

Authors:
Kenoki Ohuchida Kazuhiro Mizumoto Tadashi Kayashima Hayato Fujita Taiki Moriyama Takao Ohtsuka Junji Ueda Eishi Nagai Makoto Hashizume Masao Tanaka

Ann Surg Oncol 2011 Aug 23;18(8):2381-7. Epub 2011 Feb 23.

Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1245/s10434-011-1602-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136688PMC
August 2011

Predicting the chemosensitivity of pancreatic cancer cells by quantifying the expression levels of genes associated with the metabolism of gemcitabine and 5-fluorouracil.

Authors:
Nobuaki Kurata Hayato Fujita Kenoki Ohuchida Kazuhiro Mizumoto Prawej Mahawithitwong Hiroshi Sakai Manabu Onimaru Tatsuya Manabe Takao Ohtsuka Masao Tanaka

Int J Oncol 2011 Aug 26;39(2):473-82. Epub 2011 May 26.

Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan.

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http://dx.doi.org/10.3892/ijo.2011.1058DOI Listing
August 2011

Insig2 is overexpressed in pancreatic cancer and its expression is induced by hypoxia.

Authors:
Tadashi Kayashima Kohei Nakata Kenoki Ohuchida Junji Ueda Kengo Shirahane Hayato Fujita Lin Cui Kazuhiro Mizumoto Masao Tanaka

Cancer Sci 2011 Jun 27;102(6):1137-43. Epub 2011 Apr 27.

Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1111/j.1349-7006.2011.01936.xDOI Listing
June 2011

Expression of claudin-4 (CLDN4) mRNA in intraductal papillary mucinous neoplasms of the pancreas.

Authors:
Kosuke Tsutsumi Norihiro Sato Lin Cui Kazuhiro Mizumoto Yoshihiko Sadakari Hayato Fujita Kenoki Ohuchida Takao Ohtsuka Shunichi Takahata Masao Tanaka

Mod Pathol 2011 Apr 19;24(4):533-41. Epub 2010 Nov 19.

Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1038/modpathol.2010.218DOI Listing
April 2011

Adenoviral therapy is more effective in gemcitabine-resistant pancreatic cancer than in gemcitabine-sensitive cells.

Authors:
Takaharu Yasui Kenoki Ohuchida Ming Zhao Lin Cui Manabu Onimaru Takuya Egami Hayato Fujita Takao Ohtsuka Kazuhiro Mizumoto Kunio Matsumoto Masao Tanaka

Anticancer Res 2011 Apr;31(4):1279-87

Department of Surgery and Oncology, Kyushu University, Fukuoka 812-8582, Japan.

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April 2011

High EGFR mRNA expression is a prognostic factor for reduced survival in pancreatic cancer after gemcitabine-based adjuvant chemotherapy.

Authors:
Hayato Fujita Kenoki Ohuchida Kazuhiro Mizumoto Soichi Itaba Tetsuhide Ito Kohei Nakata Jun Yu Tadashi Kayashima Akifumi Hayashi Ryota Souzaki Tatsuro Tajiri Manabu Onimaru Tatsuya Manabe Takao Ohtsuka Masao Tanaka

Int J Oncol 2011 Mar 17;38(3):629-41. Epub 2011 Jan 17.

Department of Surgery and Oncology, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.3892/ijo.2011.908DOI Listing
March 2011

Tumor-stroma interactions reduce the efficacy of adenoviral therapy through the HGF-MET pathway.

Authors:
Takaharu Yasui Kenoki Ohuchida Ming Zhao Manabu Onimaru Takuya Egami Hayato Fujita Takao Ohtsuka Kazuhiro Mizumoto Masao Tanaka

Cancer Sci 2011 Feb 24;102(2):484-91. Epub 2010 Nov 24.

Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1111/j.1349-7006.2010.01783.xDOI Listing
February 2011

MicroRNA-203 expression as a new prognostic marker of pancreatic adenocarcinoma.

Authors:
Naoki Ikenaga Kenoki Ohuchida Kazuhiro Mizumoto Jun Yu Tadashi Kayashima Hiroshi Sakai Hayato Fujita Kohei Nakata Masao Tanaka

Ann Surg Oncol 2010 Dec 22;17(12):3120-8. Epub 2010 Jul 22.

Departments of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1245/s10434-010-1188-8DOI Listing
December 2010

alpha-Smooth Muscle Actin Expressing Stroma Promotes an Aggressive Tumor Biology in Pancreatic Ductal Adenocarcinoma.

Authors:
Hayato Fujita Kenoki Ohuchida Kazuhiro Mizumoto Kohei Nakata Jun Yu Tadashi Kayashima Lin Cui Tatsuya Manabe Takao Ohtsuka Masao Tanaka

Pancreas 2010 11 7;39(8):1254-1262. Epub 2010 May 7.

From the Departments of *Surgery and Oncology, and daggerAdvanced Medical Initiatives, Graduate School of Medical Sciences, Kyushu University; double daggerKyushu University Hospital Cancer Center; and section signDepartment of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1097/MPA.0b013e3181dbf647DOI Listing
November 2010

MicroRNA miR-17-5p is overexpressed in pancreatic cancer, associated with a poor prognosis, and involved in cancer cell proliferation and invasion.

Authors:
Jun Yu Kenoki Ohuchida Kazuhiro Mizumoto Hayato Fujita Kouhei Nakata Masao Tanaka

Cancer Biol Ther 2010 Oct 15;10(8):748-57. Epub 2010 Oct 15.

Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.4161/cbt.10.8.13083DOI Listing
October 2010

A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B.

Authors:
Toshimasa Yamauchi Kazuo Hara Shiro Maeda Kazuki Yasuda Atsushi Takahashi Momoko Horikoshi Masahiro Nakamura Hayato Fujita Niels Grarup Stephane Cauchi Daniel P K Ng Ronald C W Ma Tatsuhiko Tsunoda Michiaki Kubo Hirotaka Watada Hiroshi Maegawa Miki Okada-Iwabu Masato Iwabu Nobuhiro Shojima Hyoung Doo Shin Gitte Andersen Daniel R Witte Torben Jørgensen Torsten Lauritzen Annelli Sandbæk Torben Hansen Toshihiko Ohshige Shintaro Omori Ikuo Saito Kohei Kaku Hiroshi Hirose Wing-Yee So Delphine Beury Juliana C N Chan Kyong Soo Park E Shyong Tai Chikako Ito Yasushi Tanaka Atsunori Kashiwagi Ryuzo Kawamori Masato Kasuga Philippe Froguel Oluf Pedersen Naoyuki Kamatani Yusuke Nakamura Takashi Kadowaki

Nat Genet 2010 Oct 5;42(10):864-8. Epub 2010 Sep 5.

Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1038/ng.660DOI Listing
October 2010

Gene expression levels as predictive markers of outcome in pancreatic cancer after gemcitabine-based adjuvant chemotherapy.

Authors:
Hayato Fujita Kenoki Ohuchida Kazuhiro Mizumoto Soichi Itaba Tetsuhide Ito Kohei Nakata Jun Yu Tadashi Kayashima Ryota Souzaki Tatsuro Tajiri Tatsuya Manabe Takao Ohtsuka Masao Tanaka

Neoplasia 2010 Oct;12(10):807-17

Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950330PMC
http://dx.doi.org/10.1593/neo.10458DOI Listing
October 2010

CD10+ pancreatic stellate cells enhance the progression of pancreatic cancer.

Authors:
Naoki Ikenaga Kenoki Ohuchida Kazuhiro Mizumoto Lin Cui Tadashi Kayashima Katsuya Morimatsu Taiki Moriyama Kohei Nakata Hayato Fujita Masao Tanaka

Gastroenterology 2010 Sep 8;139(3):1041-51, 1051.e1-8. Epub 2010 Jun 8.

Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1053/j.gastro.2010.05.084DOI Listing
September 2010

MicroRNA, hsa-miR-200c, is an independent prognostic factor in pancreatic cancer and its upregulation inhibits pancreatic cancer invasion but increases cell proliferation.

Authors:
Jun Yu Kenoki Ohuchida Kazuhiro Mizumoto Norihiro Sato Tadashi Kayashima Hayato Fujita Kouhei Nakata Masao Tanaka

Mol Cancer 2010 Jun 28;9:169. Epub 2010 Jun 28.

Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1186/1476-4598-9-169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909980PMC
June 2010

Tumor-stromal interactions with direct cell contacts enhance proliferation of human pancreatic carcinoma cells.

Authors:
Hayato Fujita Kenoki Ohuchida Kazuhiro Mizumoto Takuya Egami Kei Miyoshi Taiki Moriyama Lin Cui Jun Yu Ming Zhao Tatsuya Manabe Masao Tanaka

Cancer Sci 2009 Dec 19;100(12):2309-17. Epub 2009 Aug 19.

Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://doi.wiley.com/10.1111/j.1349-7006.2009.01317.x
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http://dx.doi.org/10.1111/j.1349-7006.2009.01317.xDOI Listing
December 2009

S100A4 mRNA is a diagnostic and prognostic marker in pancreatic carcinoma.

Authors:
Naoki Ikenaga Kenoki Ohuchida Kazuhiro Mizumoto Jun Yu Hayato Fujita Kohei Nakata Junji Ueda Norihiro Sato Eishi Nagai Masao Tanaka

J Gastrointest Surg 2009 Oct 4;13(10):1852-8. Epub 2009 Aug 4.

Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Fukuoka, 812-8582, Japan.

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http://dx.doi.org/10.1007/s11605-009-0978-4DOI Listing
October 2009

LIM only 4 is overexpressed in late stage pancreas cancer.

Authors:
Jun Yu Kenoki Ohuchida Kohei Nakata Kazuhiro Mizumoto Lin Cui Hayato Fujita Hiroshi Yamaguchi Takuya Egami Hidehisa Kitada Masao Tanaka

Mol Cancer 2008 Dec 22;7:93. Epub 2008 Dec 22.

Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1186/1476-4598-7-93DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628350PMC
December 2008

Quantitative analysis of hTERT mRNA levels in cells microdissected from cytological specimens.

Authors:
Hayato Fujita Kenoki Ohuchida Kazuhiro Mizumoto Takuya Egami Yoshihiro Miyasaka Hiroshi Yamaguchi Jun Yu Lin Cui Manabu Onimaru Shunichi Takahata Masazumi Tsuneyoshi Masao Tanaka

Cancer Sci 2008 Nov 15;99(11):2244-51. Epub 2008 Sep 15.

Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://doi.wiley.com/10.1111/j.1349-7006.2008.00930.x
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http://dx.doi.org/10.1111/j.1349-7006.2008.00930.xDOI Listing
November 2008

Down-regulation of deoxycytidine kinase enhances acquired resistance to gemcitabine in pancreatic cancer.

Authors:
Seiji Ohhashi Kenoki Ohuchida Kazuhiro Mizumoto Hayato Fujita Takuya Egami Jun Yu Hiroki Toma Shoko Sadatomi Eishi Nagai Masao Tanaka

Anticancer Res 2008 Jul-Aug;28(4B):2205-12

Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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September 2008

Increased expression of ADAM 9 and ADAM 15 mRNA in pancreatic cancer.

Authors:
Daisuke Yamada Kenoki Ohuchida Kazuhiro Mizumoto Seiji Ohhashi Jun Yu Takuya Egami Hayato Fujita Eishi Nagai Masao Tanaka

Anticancer Res 2007 Mar-Apr;27(2):793-9

Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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May 2007

Overexpression of c-met in the early stage of pancreatic carcinogenesis; altered expression is not sufficient for progression from chronic pancreatitis to pancreatic cancer.

Authors:
Jun Yu Kenoki Ohuchida Kazuhiro Mizumoto Nami Ishikawa Yasuhiro Ogura Daisuke Yamada Takuya Egami Hayato Fujita Seiji Ohashi Eishi Nagai Masao Tanaka

World J Gastroenterol 2006 Jun;12(24):3878-82

Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4087937PMC
http://dx.doi.org/10.3748/wjg.v12.i24.3878DOI Listing
June 2006