Dr Hassan Ahmed Ismail, PhD - Federal Ministry of Health, Sudan - Neglected Tropical Diseases (NTDs) Control

Dr Hassan Ahmed Ismail

PhD

Federal Ministry of Health, Sudan

Neglected Tropical Diseases (NTDs) Control

Khartoum, Khartoum State | Sudan

Main Specialties: Biology

Additional Specialties: Parasitology and Molecular Biology

ORCID logohttps://orcid.org/0000-0001-6554-9596

Dr Hassan Ahmed Ismail, PhD - Federal Ministry of Health, Sudan - Neglected Tropical Diseases (NTDs) Control

Dr Hassan Ahmed Ismail

PhD

Introduction

Primary Affiliation: Federal Ministry of Health, Sudan - Khartoum, Khartoum State , Sudan

Specialties:

Additional Specialties:

Education

Jul 2009
University of Khartoum
M.Sc
Zoology (parasitology)
Sep 1998
University of Khartoum
Bachelor
Zoology

Experience

May 2006
Experience in Parasitology, Molecular cell biology, Molecular parasitology, Schistosomiasis epidemiology and Malacology and control of Neglected Tropical Diseases (NTDs)
Research Investigator
Federal Ministry of Health, Community Intervention Division

Publications

12Publications

329Reads

10Profile Views

Epidemiological findings and policy implications from the nationwide schistosomiasis and intestinal helminthiasis survey in Sudan.

Parasit Vectors 2019 Sep 5;12(1):429. Epub 2019 Sep 5.

Department of Tropical Medicine and Parasitology, Seoul National University College of Medicine, Daehak-ro, Seoul, 03080, South Korea.

Background: The World Health Assembly endorsed the WHO Neglected Tropical Disease (NTD) Roadmap in 2013, in which NTDs were suggested as tracers of equity in the assessment of progress towards the Sustainable Development Goals. Nationwide surveys were undertaken in all 18 states of Sudan to identify the geographical distribution and to estimate the prevalence and intensity of schistosomiasis and other intestinal helminthiases from December 2016 to March 2017.

Methods: We used two-stage random sampling. Each district was subdivided into one to three different ecological zones (EZs) based on proximity to water bodies. Probability-proportional-to-size sampling was used to select schools from each EZ. We estimated schistosomiasis and intestinal helminthiasis prevalence by the centrifugation method and Kato-Katz smears. Multi-level mixed-effect models were used to investigate the relationship between the prevalence of infections and risk factors, including improved water or latrine status at the household or school level. We estimated the cost-effectiveness of a one-time mass drug administration (MDA) intervention with 75% coverage at the district and EZ levels.

Results: A total of 105,167 students from 1772 schools were surveyed. The overall egg-positive rates were: Schistosoma haematobium, 5.2%; S. mansoni, 0.06%; and intestinal helminths, 5.47%. Severe endemic areas were concentrated in East and South Darfur States. Children living in a house or attending schools with an improved latrine were less likely to be infected with schistosomiasis than those without a latrine (adjusted odds ratio, aOR: 0.45, 95% confidence interval, CI: 0.41-0.51 and aOR: 0.75, 95% CI: 0.70-0.81 at the household or the school levels, respectively). Open defecation was strongly associated with schistosomiasis (aOR: 1.50, 95% CI: 1.35-1.66). In community-wide mass treatment at the district level with an 8% threshold for schistosomiasis, 2.2 million people would not benefit from MDA interventions with 75% coverage despite high endemicity, whilst 1.7 million people would receive the MDA intervention unnecessarily. EZ-level MDA was estimated to be more cost-effective than district-level administration under all circumstances.

Conclusions: Our findings provide updated prevalence figures to guide preventive chemotherapy programmes for schistosomiasis and intestinal helminthiasis in Sudan. Schistosomiasis was found to be common among the inhabitants of fragile and conflict-affected areas. In addition, we found that MDA interventions would be more cost-effective at the sub-district level than at the district level, and there was a strong association between schistosomiasis prevalence and latrine status, at both the household and school levels. This study will help the Sudanese government and its neighbouring countries develop adequate control and elimination strategies.

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http://dx.doi.org/10.1186/s13071-019-3689-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728938PMC
September 2019
2 Reads
3.430 Impact Factor

Modulated Gene Expression of Infected Retinal Pigment Epithelial Cell Line (ARPE-19) via PI3K/Akt or mTOR Signal Pathway.

Korean J Parasitol 2018 Apr 30;56(2):135-145. Epub 2018 Apr 30.

Department of Medical Science & Infection Biology, Chungnam National University, School of Medicine, Daejeon 34134, Korea.

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http://dx.doi.org/10.3347/kjp.2018.56.2.135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976016PMC
April 2018
15 Reads
0.965 Impact Factor

IL-12 and IL-23 Production in Toxoplasma gondii- or LPS-Treated Jurkat T Cells via PI3K and MAPK Signaling Pathways.

Korean J Parasitol 2017 Dec 31;55(6):613-622. Epub 2017 Dec 31.

Department of Infection Biology, Chungnam National University School of Medicine, Daejeon 34134, Korea.

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http://parasitol.kr/journal/view.php?doi=10.3347/kjp.2017.55
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http://dx.doi.org/10.3347/kjp.2017.55.6.613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776897PMC
December 2017
29 Reads
0.965 Impact Factor

Genetic Diversity of Schistosoma haematobium Eggs Isolated from Human Urine in Sudan.

Korean J Parasitol 2015 Jun 30;53(3):271-7. Epub 2015 Jun 30.

Department of Infection Biology, Chungnam National University School of Medicine, Daejeon 301-131, Korea.

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http://dx.doi.org/10.3347/kjp.2015.53.3.271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510678PMC
June 2015
19 Reads
0.965 Impact Factor

Reduction of urogenital schistosomiasis with an integrated control project in Sudan.

PLoS Negl Trop Dis 2015 Jan 8;9(1):e3423. Epub 2015 Jan 8.

Department of Parasitology and Tropical Medicine, Seoul National University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1371/journal.pntd.0003423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288734PMC
January 2015
7 Reads

Fasciola hepatica in snails collected from water-dropwort fields using PCR.

Korean J Parasitol 2014 Dec 23;52(6):645-52. Epub 2014 Dec 23.

Department of Infection Biology, Chungnam National University School of Medicine, Daejeon 301-131, Korea.

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http://dx.doi.org/10.3347/kjp.2014.52.6.645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277027PMC
December 2014
110 Reads
0.965 Impact Factor

Induction of protective immune responses by a multiantigenic DNA vaccine encoding GRA7 and ROP1 of Toxoplasma gondii.

Clin Vaccine Immunol 2012 May 14;19(5):666-74. Epub 2012 Mar 14.

Department of Infection Biology, Research Institute for Medical Sciences, Chungnam National University School of Medicine, Daejeon, South Korea.

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http://dx.doi.org/10.1128/CVI.05385-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346315PMC
May 2012
24 Reads

Gene expression profiles in genetically different mice infected with Toxoplasma gondii: ALDH1A2, BEX2, EGR2, CCL3 and PLAU.

Korean J Parasitol 2012 Mar 6;50(1):7-13. Epub 2012 Mar 6.

Department of Infection Biology, Research Institute for Medical Science, Chungnam National University School of Medicine, Daejeon 301-131, Korea.

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http://dx.doi.org/10.3347/kjp.2012.50.1.7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309055PMC
March 2012
21 Reads
0.965 Impact Factor

Intestinal parasite infections in pigs and beef cattle in rural areas of Chungcheongnam-do, Korea.

Korean J Parasitol 2010 Dec 16;48(4):347-9. Epub 2010 Dec 16.

Department of Infection Biology, Chungnam National University School of Medicine, Daejeon 301-131, Korea.

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http://dx.doi.org/10.3347/kjp.2010.48.4.347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018588PMC
December 2010
8 Reads
0.965 Impact Factor

Top co-authors

Guang-Ho Cha
Guang-Ho Cha

Chungnam National University School of Medicine

7
In-Wook Choi
In-Wook Choi

Chungnam National University School of Medicine

5
Wei Zhou
Wei Zhou

University of Michigan

3
Jae-Min Yuk
Jae-Min Yuk

Chungnam National University

2
Chung Hyeon Oh
Chung Hyeon Oh

Korea International Cooperation Agencies

2
Jia-Qi Chu
Jia-Qi Chu

Chungnam National University School of Medicine

2