Publications by authors named "Hasnah Osman"

100Publications

Poly(cyclodextrin-ionic liquid) based ferrofluid: A new class of magnetic colloid for dispersive liquid phase microextraction of polycyclic aromatic hydrocarbons from food samples prior to GC-FID analysis.

Food Chem 2020 Jun 14;314:126214. Epub 2020 Jan 14.

Department of Chemistry, Faculty of Science, Universiti Malaya, Kuala Lumpur 50603, Malaysia; Universiti Malaya Centre for Ionic Liquids (UMCiL), Department of Chemistry, Faculty of Science, Universiti Malaya, Kuala Lumpur 50603, Malaysia. Electronic address:

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http://dx.doi.org/10.1016/j.foodchem.2020.126214DOI Listing
June 2020

Magnetic poly(β-cyclodextrin-ionic liquid) nanocomposites for micro-solid phase extraction of selected polycyclic aromatic hydrocarbons in rice samples prior to GC-FID analysis.

Food Chem 2019 Apr 3;278:322-332. Epub 2018 Nov 3.

Department of Chemistry, Faculty of Science, Universiti Malaya, Kuala Lumpur 50603, Malaysia; Universiti Malaya Centre for Ionic Liquids (UMCiL), Department of Chemistry, Faculty of Science, Universiti Malaya, Kuala Lumpur 50603, Malaysia. Electronic address:

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http://dx.doi.org/10.1016/j.foodchem.2018.10.145DOI Listing
April 2019

Molecular docking studies of coumarin hybrids as potential acetylcholinesterase, butyrylcholinesterase, monoamine oxidase A/B and β-amyloid inhibitors for Alzheimer's disease.

Chem Cent J 2018 Dec 4;12(1):128. Epub 2018 Dec 4.

Industrial Chemistry Programme, Faculty of Science and Natural Resources, Universiti Malaysia Sabah, 88400, Kota Kinabalu, Sabah, Malaysia.

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http://dx.doi.org/10.1186/s13065-018-0497-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768047PMC
December 2018

The Effects of 4-Hydroxybenzoic Acid Identified from Bamboo () Shoots on Kv1.4 Channel.

Malays J Med Sci 2018 Feb 28;25(1):101-113. Epub 2018 Feb 28.

Center for Neuroscience Services and Research, Universiti Sains Malaysia, Jalan Hospital Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.

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http://dx.doi.org/10.21315/mjms2018.25.1.12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862056PMC
February 2018

The Effect of 4-hydroxybenzaldehyde on the γ-aminobutyric Acid Type A Receptor.

Malays J Med Sci 2017 Mar 14;24(2):94-99. Epub 2017 Apr 14.

Center for Neuroscience Services and Research, Universiti Sains Malaysia, Jalan Hospital Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.

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http://dx.doi.org/10.21315/mjms2017.24.2.12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566067PMC
March 2017

3,5-Bis(arylidene)-4-piperidones as potential dengue protease inhibitors.

Acta Pharm Sin B 2017 Jul 4;7(4):479-484. Epub 2017 May 4.

School of Chemical Sciences, Universiti Sains Malaysia, Pulau Pinang 11800 USM, Malaysia.

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http://dx.doi.org/10.1016/j.apsb.2017.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518655PMC
July 2017

One-pot microwave assisted stereoselective synthesis of novel dihydro-2'H-spiro[indene-2,1'-pyrrolo-[3,4-c]pyrrole]-tetraones and evaluation of their antimycobacterial activity and inhibition of AChE.

Bioorg Med Chem Lett 2017 07 17;27(14):3071-3075. Epub 2017 May 17.

Department of Organic Chemistry, School of Chemistry, Madurai Kamaraj University, Madurai 625021, Tamil Nadu, India. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2017.05.050DOI Listing
July 2017

Combination of Cyclodextrin and Ionic Liquid in Analytical Chemistry: Current and Future Perspectives.

Crit Rev Anal Chem 2017 Sep 28;47(5):454-467. Epub 2017 Apr 28.

d School of Chemical Sciences , Universiti Sains Malaysia , Pulau Pinang , Malaysia.

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http://dx.doi.org/10.1080/10408347.2017.1320936DOI Listing
September 2017

Metabolomics approach for multibiomarkers determination to investigate dengue virus infection in human patients.

Acta Biochim Pol 2017 30;64(2):215-219. Epub 2017 Mar 30.

Advanced Medical and Dental Institute, University Science Malaysia, Malaysia.

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http://dx.doi.org/10.18388/abp.2015_1224DOI Listing
August 2017

Ethyl nitrobenzoate: A novel scaffold for cholinesterase inhibition.

Bioorg Chem 2017 02 11;70:27-33. Epub 2016 Nov 11.

Institute for Research in Molecular Medicine, Universiti Sains Malaysia, Minden, 11800 Penang, Malaysia.

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http://dx.doi.org/10.1016/j.bioorg.2016.11.005DOI Listing
February 2017

A facile stereoselective synthesis of dispiro-indeno pyrrolidine/pyrrolothiazole-thiochroman hybrids and evaluation of their antimycobacterial, anticancer and AchE inhibitory activities.

Bioorg Med Chem 2016 11 19;24(22):5873-5883. Epub 2016 Sep 19.

Department of Organic Chemistry, School of Chemistry, Madurai Kamaraj University, Madurai, Tamil Nadu 625 021, India. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09680896163075
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http://dx.doi.org/10.1016/j.bmc.2016.09.044DOI Listing
November 2016

Therapeutic potential of coumarins as antiviral agents.

Eur J Med Chem 2016 Nov 25;123:236-255. Epub 2016 Jul 25.

Maharishi Arvind College of Pharmacy, Ambabari, Jaipur 302 039, India.

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http://dx.doi.org/10.1016/j.ejmech.2016.07.056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115672PMC
November 2016

Metabolomics for characterization of gender differences in patients infected with dengue virus.

Asian Pac J Trop Med 2015 Jun 25;8(6):451-6. Epub 2015 Jun 25.

Advanced Medical and Dental Institute, University Science Malaysia, Malaysia; National Research Centre, Cairo, Egypt. Electronic address:

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http://dx.doi.org/10.1016/j.apjtm.2015.05.012DOI Listing
June 2015

Evaluation of the Cytotoxicity of Levodopa and its Complex with Hydroxypropyl-ß-Cyclodextrin (HP-ß-CD) to an Astrocyte Cell Line.

Malays J Med Sci 2014 Dec;21(Spec Issue):6-11

School of Health Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405804PMC
December 2014

Molecular docking studies and in vitro cholinesterase enzyme inhibitory activities of chemical constituents of Garcinia hombroniana.

Nat Prod Res 2015 15;29(1):86-90. Epub 2014 Sep 15.

a School of Chemical Sciences, Universiti Sains Malaysia , 11800 Minden , Penang , Malaysia.

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http://dx.doi.org/10.1080/14786419.2014.952228DOI Listing
March 2015

Cytotoxic benzophenone and triterpene from Garcinia hombroniana.

Bioorg Chem 2014 Jun 23;54:60-7. Epub 2014 Apr 23.

Department of Chemistry, Kohat University of Science and Technology, Kohat, 26000 Kohat, Khyber Pakhtunkhwa, Pakistan.

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http://dx.doi.org/10.1016/j.bioorg.2014.04.003DOI Listing
June 2014

Cholinesterase inhibitory triterpenoids from the bark of Garcinia hombroniana.

J Enzyme Inhib Med Chem 2015 Feb 25;30(1):133-9. Epub 2014 Mar 25.

School of Chemical Sciences, Universiti Sains Malaysia , Penang , Malaysia and.

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http://dx.doi.org/10.3109/14756366.2014.895720DOI Listing
February 2015

Synthesis and discovery of highly functionalized mono- and bis-spiro-pyrrolidines as potent cholinesterase enzyme inhibitors.

Bioorg Med Chem Lett 2014 Apr 15;24(7):1815-9. Epub 2014 Feb 15.

School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800 USM, Penang, Malaysia.

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http://dx.doi.org/10.1016/j.bmcl.2014.02.019DOI Listing
April 2014

Ionic liquid mediated synthesis of mono- and bis-spirooxindole-hexahydropyrrolidines as cholinesterase inhibitors and their molecular docking studies.

Bioorg Med Chem 2014 Feb 9;22(4):1318-28. Epub 2014 Jan 9.

School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800 Penang, Malaysia.

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https://linkinghub.elsevier.com/retrieve/pii/S09680896140000
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http://dx.doi.org/10.1016/j.bmc.2014.01.002DOI Listing
February 2014

Synthesis and evaluation of novel benzimidazole derivatives as sirtuin inhibitors with antitumor activities.

Bioorg Med Chem 2014 Jan 19;22(2):703-10. Epub 2013 Dec 19.

Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, RI 02881, United States.

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http://dx.doi.org/10.1016/j.bmc.2013.12.029DOI Listing
January 2014

Antituberculosis: synthesis and antimycobacterial activity of novel benzimidazole derivatives.

Biomed Res Int 2013 5;2013:926309. Epub 2013 Dec 5.

New Drug Discovery Research, Department of Medicinal Chemistry, Sunrise University, Alwar, Rajasthan 301030, India.

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http://dx.doi.org/10.1155/2013/926309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870127PMC
July 2014

Synthesis, characterization, and molecular docking analysis of novel benzimidazole derivatives as cholinesterase inhibitors.

Bioorg Chem 2013 Aug 4;49:33-9. Epub 2013 Jul 4.

Institute for Research in Molecular Medicine, Universiti Sains Malaysia, Minden, 11800 Penang, Malaysia.

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http://dx.doi.org/10.1016/j.bioorg.2013.06.008DOI Listing
August 2013

An expedient, ionic liquid mediated multi-component synthesis of novel piperidone grafted cholinesterase enzymes inhibitors and their molecular modeling study.

Eur J Med Chem 2013 Sep 4;67:221-9. Epub 2013 Jul 4.

School of Pharmaceutical Sciences, Universiti Sains Malaysia, Minden 11800, Penang, Malaysia.

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http://dx.doi.org/10.1016/j.ejmech.2013.06.054DOI Listing
September 2013

An expedient synthesis and screening for antiacetylcholinesterase activity of piperidine embedded novel pentacyclic cage compounds.

Med Chem 2014 Mar;10(2):228-36

Department of Chemistry, College of Sciences, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.

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http://dx.doi.org/10.2174/157340641002140131170054DOI Listing
March 2014

Synthesis and discovery of new bisadducts derived from heterocyclic aldehydes and active methylene compounds as potent antitubercular agents.

Acta Pol Pharm 2013 Mar-Apr;70(2):221-8

School of Chemical Sciences, University Sains Malaysia, Minden 11800, Penang, Malaysia.

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June 2013

Microwave assisted synthesis, cholinesterase enzymes inhibitory activities and molecular docking studies of new pyridopyrimidine derivatives.

Bioorg Med Chem 2013 Jun 1;21(11):3022-31. Epub 2013 Apr 1.

School of Pharmaceutical Sciences, Universiti Sains Malaysia, Minden 11800, Penang, Malaysia.

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http://dx.doi.org/10.1016/j.bmc.2013.03.058DOI Listing
June 2013

A facile chemo-, regio- and stereoselective synthesis and cholinesterase inhibitory activity of spirooxindole-pyrrolizine-piperidine hybrids.

Bioorg Med Chem Lett 2013 May 23;23(10):2979-83. Epub 2013 Mar 23.

School of Chemical Sciences, Universiti Sains Malaysia, 11800 USM, Penang, Malaysia.

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http://dx.doi.org/10.1016/j.bmcl.2013.03.027DOI Listing
May 2013

2-Hy-droxy-5-[(E)-2-methyl-benzyl-idene]-8-(2-methyl-phen-yl)-9-phenyl-3,10-diaza-hexa-cyclo-[10.7.1.1(3,7).0(2,11).0(7,11).0(16,20)]henicosa-1(20),12,14,16,18-pentaen-6-one.

Acta Crystallogr Sect E Struct Rep Online 2012 Dec 17;68(Pt 12):o3375. Epub 2012 Nov 17.

Department of Chemistry, College of Sciences, King Saud University, PO Box 2455, Riyadh 11451, Saudi Arabia.

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http://dx.doi.org/10.1107/S160053681204648XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588971PMC
December 2012

Anti-proliferation effects of benzimidazole derivatives on HCT-116 colon cancer and MCF-7 breast cancer cell lines.

Asian Pac J Cancer Prev 2012 ;13(8):4075-9

Chemistry Department, Faculty of Science, Hadhramout University of Science and Technology (HUST), Mukalla, Hadhramout, Yemen.

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http://dx.doi.org/10.7314/apjcp.2012.13.8.4075DOI Listing
April 2013

Straightforward synthesis of novel 1-(2'-α-O-D-glucopyranosyl ethyl) 2-arylbenzimidazoles.

Molecules 2012 Aug 17;17(8):9887-99. Epub 2012 Aug 17.

School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800 Minden, Penang, Malaysia.

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http://dx.doi.org/10.3390/molecules17089887DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268058PMC
August 2012

Diaminobenzene schiff base, a novel class of DNA minor groove binder.

Int J Oncol 2012 Aug 18;41(2):504-10. Epub 2012 May 18.

Department of Pharmacology, Universiti Sains Malaysia, Penang, Malaysia.

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http://dx.doi.org/10.3892/ijo.2012.1491DOI Listing
August 2012

3β-Chloro-5α-cholestan-6-one.

Acta Crystallogr Sect E Struct Rep Online 2012 Apr 28;68(Pt 4):o1211-2. Epub 2012 Mar 28.

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http://dx.doi.org/10.1107/S1600536812012482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344147PMC
April 2012

Microwave-assisted synthesis and antioxidant properties of hydrazinyl thiazolyl coumarin derivatives.

Chem Cent J 2012 Apr 17;6(1):32. Epub 2012 Apr 17.

School of Chemical Sciences, Universiti Sains Malaysia, 11800, Penang, Malaysia.

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http://dx.doi.org/10.1186/1752-153X-6-32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527148PMC
April 2012

4-Methyl-2-oxo-2H-chromen-7-yl 4-fluoro-benzene-sulfonate.

Acta Crystallogr Sect E Struct Rep Online 2012 Mar 10;68(Pt 3):o641-2. Epub 2012 Feb 10.

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http://dx.doi.org/10.1107/S1600536812004394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295434PMC
March 2012

The Chemical Components of Sesbania grandiflora Root and Their Antituberculosis Activity.

Pharmaceuticals (Basel) 2012 Aug 23;5(8):882-9. Epub 2012 Aug 23.

School of Chemical Sciences, University of Science Malaysia, Minden 11800, Penang, Malaysia.

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http://dx.doi.org/10.3390/ph5080882DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763669PMC
August 2012

4-Methyl-2-oxo-2H-chromen-7-yl 4-meth-oxy-benzene-sulfonate.

Acta Crystallogr Sect E Struct Rep Online 2011 Dec 30;67(Pt 12):o3457. Epub 2011 Nov 30.

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http://dx.doi.org/10.1107/S1600536811049476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239087PMC
December 2011

3-Hy-droxy-2-(4-meth-oxy-benzene-sulfonamido)-butanoic acid.

Acta Crystallogr Sect E Struct Rep Online 2011 Dec 12;67(Pt 12):o3275. Epub 2011 Nov 12.

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http://dx.doi.org/10.1107/S1600536811046502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3238932PMC
December 2011

2-[(E)-(2,4-Dichloro-benzyl-idene)amino]-isoindoline-1,3-dione.

Acta Crystallogr Sect E Struct Rep Online 2011 Jul 18;67(Pt 7):o1712. Epub 2011 Jun 18.

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http://dx.doi.org/10.1107/S1600536811023063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151809PMC
July 2011

7-Fluoro-4-oxochromene-3-carbaldehyde.

Acta Crystallogr Sect E Struct Rep Online 2011 Apr 2;67(Pt 4):o766. Epub 2011 Mar 2.

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http://dx.doi.org/10.1107/S1600536811007045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3099754PMC
April 2011

Synthesis and antimicrobial properties of some new thiazolyl coumarin derivatives.

Eur J Med Chem 2011 Sep 7;46(9):3788-94. Epub 2011 Jun 7.

School of Chemical Sciences, Universiti Sains Malaysia, 11800 Penang, Malaysia.

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https://linkinghub.elsevier.com/retrieve/pii/S02235234110042
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http://dx.doi.org/10.1016/j.ejmech.2011.05.044DOI Listing
September 2011

Synthesis and biological evaluation of novel 6, 7-dimethoxy-3-(4-pyridyl)-2,3,3a,4-tetrahydroindeno[1,2-c]pyrazol-2-yl-4-substituted phenylmethanone/ethanone derivatives.

J Enzyme Inhib Med Chem 2012 Feb 3;27(1):155-9. Epub 2011 Jun 3.

New Drug Discovery Research, Department of Medicinal Chemistry, Alwar Pharmacy College, Alwar, Rajasthan, India.

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http://dx.doi.org/10.3109/14756366.2011.581240DOI Listing
February 2012

Synthesis and discovery of novel hexacyclic cage compounds as inhibitors of acetylcholinesterase.

Bioorg Med Chem Lett 2011 Jul 8;21(13):3997-4000. Epub 2011 May 8.

School of Chemical Sciences, Universiti Sains Malaysia, Penang 11800, Malaysia.

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http://dx.doi.org/10.1016/j.bmcl.2011.05.003DOI Listing
July 2011

(E)-2-(4-Methylbenzylidene)hydrazinecarboxamide.

Acta Crystallogr Sect E Struct Rep Online 2011 Jan 8;67(Pt 2):o242. Epub 2011 Jan 8.

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http://dx.doi.org/10.1107/S1600536810052797DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051666PMC
January 2011

Substituted spiro [2.3'] oxindolespiro [3.2″]-5,6-dimethoxy-indane-1″-one-pyrrolidine analogue as inhibitors of acetylcholinesterase.

Bioorg Med Chem Lett 2010 Dec 26;20(23):7064-6. Epub 2010 Sep 26.

Pharmacogenetic and Novel Therapeutics Research, Institute for Research in Molecular Medicine, Universiti Sains Malaysia, Pennag, Malaysia.

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http://dx.doi.org/10.1016/j.bmcl.2010.09.108DOI Listing
December 2010

Determination of underivatized long chain fatty acids using RP-HPLC with capacitively coupled contactless conductivity detection.

Talanta 2010 Apr 22;81(1-2):20-4. Epub 2009 Nov 22.

School of Chemical Sciences, Universiti Sains Malaysia, 11800 Penang, Malaysia.

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http://dx.doi.org/10.1016/j.talanta.2009.11.030DOI Listing
April 2010

3-Acetyl-4-hy-droxy-6,7-dimethyl-2H-chromen-2-one.

Acta Crystallogr Sect E Struct Rep Online 2010 Nov 13;66(Pt 12):o3129-30. Epub 2010 Nov 13.

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http://dx.doi.org/10.1107/S1600536810045010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011552PMC
November 2010

3-[(E)-3-(2,4-Dichloro-phen-yl)prop-2-en-oyl]-4-hy-droxy-2H-chromen-2-one.

Acta Crystallogr Sect E Struct Rep Online 2010 Oct 31;66(Pt 11):o3022-3. Epub 2010 Oct 31.

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http://dx.doi.org/10.1107/S1600536810043837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009251PMC
October 2010

3-Methyl-4-[(E)-3-thien-ylmethyl-idene-amino]-1H-1,2,4-triazole-5(4H)-thione.

Acta Crystallogr Sect E Struct Rep Online 2010 Oct 20;66(Pt 11):o2861-2. Epub 2010 Oct 20.

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http://dx.doi.org/10.1107/S1600536810041152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009062PMC
October 2010