Publications by authors named "Hashem Shahin"

18Publications

Genomic analysis of inherited hearing loss in the Palestinian population.

Authors:
Amal Abu Rayyan Lara Kamal Silvia Casadei Zippora Brownstein Fouad Zahdeh Hashem Shahin Christina Canavati Dima Dweik Tamara Jaraysa Grace Rabie Ryan J Carlson Suleyman Gulsuner Ming K Lee Karen B Avraham Tom Walsh Mary-Claire King Moien N Kanaan

Proc Natl Acad Sci U S A 2020 08 3;117(33):20070-20076. Epub 2020 Aug 3.

Department of Biology, Bethlehem University, Bethlehem 72372, Palestine.

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August 2020

Reply to Tzoulis et al.: Genetic and clinical heterogeneity of essential tremor.

Authors:
Hilal Unal Gulsuner Suleyman Gulsuner Fatma Nazli Mercan Onur Emre Onat Tom Walsh Hashem Shahin Ming K Lee Okan Dogu Tulay Kansu Haluk Topaloglu Bulent Elibol Cenk Akbostanci Mary-Claire King Tayfun Ozcelik Ayse B Tekinay

Proc Natl Acad Sci U S A 2015 May 30;112(18):E2269. Epub 2015 Mar 30.

Institute of Materials Science and Nanotechnology, National Nanotechnology Research Center (UNAM), and.

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May 2015

Mitochondrial serine protease HTRA2 p.G399S in a kindred with essential tremor and Parkinson disease.

Authors:
Hilal Unal Gulsuner Suleyman Gulsuner Fatma Nazli Mercan Onur Emre Onat Tom Walsh Hashem Shahin Ming K Lee Okan Dogu Tulay Kansu Haluk Topaloglu Bulent Elibol Cenk Akbostanci Mary-Claire King Tayfun Ozcelik Ayse B Tekinay

Proc Natl Acad Sci U S A 2014 Dec 24;111(51):18285-90. Epub 2014 Nov 24.

Institute of Materials Science and Nanotechnology, National Nanotechnology Research Center (UNAM), and

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December 2014

Spatial and temporal mapping of de novo mutations in schizophrenia to a fetal prefrontal cortical network.

Authors:
Suleyman Gulsuner Tom Walsh Amanda C Watts Ming K Lee Anne M Thornton Silvia Casadei Caitlin Rippey Hashem Shahin Vishwajit L Nimgaonkar Rodney C P Go Robert M Savage Neal R Swerdlow Raquel E Gur David L Braff Mary-Claire King Jon M McClellan

Cell 2013 Aug;154(3):518-29

Department of Medicine and Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA.

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August 2013

Mutations in OTOGL, encoding the inner ear protein otogelin-like, cause moderate sensorineural hearing loss.

Authors:
Kemal O Yariz Duygu Duman Celia Zazo Seco Julia Dallman Mingqian Huang Theo A Peters Asli Sirmaci Na Lu Margit Schraders Isaac Skromne Jaap Oostrik Oscar Diaz-Horta Juan I Young Suna Tokgoz-Yilmaz Ozlem Konukseven Hashem Shahin Lisette Hetterschijt Moien Kanaan Anne M M Oonk Yvonne J K Edwards Huawei Li Semra Atalay Susan Blanton Alexandra A Desmidt Xue-Zhong Liu Ronald J E Pennings Zhongmin Lu Zheng-Yi Chen Hannie Kremer Mustafa Tekin

Am J Hum Genet 2012 11;91(5):872-82

John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL 33136, USA.

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November 2012

GPSM2 mutations cause the brain malformations and hearing loss in Chudley-McCullough syndrome.

Authors:
Dan Doherty Albert E Chudley Gail Coghlan Gisele E Ishak A Micheil Innes Edmond G Lemire R Curtis Rogers Aizeddin A Mhanni Ian G Phelps Steven J M Jones Shing H Zhan Anthony P Fejes Hashem Shahin Moien Kanaan Hatice Akay Mustafa Tekin Barbara Triggs-Raine Teresa Zelinski

Am J Hum Genet 2012 Jun 10;90(6):1088-93. Epub 2012 May 10.

Department of Pediatrics, University of Washington, Seattle Children's Hospital, 98105, USA.

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June 2012

Targeted genomic capture and massively parallel sequencing to identify genes for hereditary hearing loss in Middle Eastern families.

Authors:
Zippora Brownstein Lilach M Friedman Hashem Shahin Varda Oron-Karni Nitzan Kol Amal Abu Rayyan Thomas Parzefall Dorit Lev Stavit Shalev Moshe Frydman Bella Davidov Mordechai Shohat Michele Rahile Sari Lieberman Ephrat Levy-Lahad Ming K Lee Noam Shomron Mary-Claire King Tom Walsh Moien Kanaan Karen B Avraham

Genome Biol 2011 Sep 14;12(9):R89. Epub 2011 Sep 14.

Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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September 2011

A mouse model for human hearing loss DFNB30 due to loss of function of myosin IIIA.

Authors:
Vanessa L Walsh Dorith Raviv Amiel A Dror Hashem Shahin Tom Walsh Moien N Kanaan Karen B Avraham Mary-Claire King

Mamm Genome 2011 Apr 17;22(3-4):170-7. Epub 2010 Dec 17.

Department of Medicine, University of Washington, Seattle, WA 98195-7720, USA.

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April 2011

Genomic duplication and overexpression of TJP2/ZO-2 leads to altered expression of apoptosis genes in progressive nonsyndromic hearing loss DFNA51.

Authors:
Tom Walsh Sarah B Pierce Danielle R Lenz Zippora Brownstein Orit Dagan-Rosenfeld Hashem Shahin Wendy Roeb Shane McCarthy Alex S Nord Carlos R Gordon Ziva Ben-Neriah Jonathan Sebat Moien Kanaan Ming K Lee Moshe Frydman Mary-Claire King Karen B Avraham

Am J Hum Genet 2010 Jul 17;87(1):101-9. Epub 2010 Jun 17.

Department of Medicine (Medical Genetics), University of Washington, Seattle, WA 98195, USA.

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July 2010

Whole exome sequencing and homozygosity mapping identify mutation in the cell polarity protein GPSM2 as the cause of nonsyndromic hearing loss DFNB82.

Authors:
Tom Walsh Hashem Shahin Tal Elkan-Miller Ming K Lee Anne M Thornton Wendy Roeb Amal Abu Rayyan Suheir Loulus Karen B Avraham Mary-Claire King Moien Kanaan

Am J Hum Genet 2010 Jul 17;87(1):90-4. Epub 2010 Jun 17.

Department of Medicine, Division of Medical Genetics, University of Washington, Seattle, WA 98195, USA.

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July 2010

Nonsense mutation of the stereociliar membrane protein gene PTPRQ in human hearing loss DFNB84.

Authors:
Hashem Shahin Michael Rahil Amal Abu Rayan Karen B Avraham Mary-Claire King Moien Kanaan Tom Walsh

J Med Genet 2010 Sep 14;47(9):643-5. Epub 2010 May 14.

Department of Life Sciences, Bethlehem University, Bethlehem, Palestinian National Authority.

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September 2010

A truncating mutation in SERPINB6 is associated with autosomal-recessive nonsyndromic sensorineural hearing loss.

Authors:
Asli Sirmaci Seyra Erbek Justin Price Mingqian Huang Duygu Duman F Başak Cengiz Güney Bademci Suna Tokgöz-Yilmaz Burcu Hişmi Hilal Ozdağ Banu Oztürk Sevsen Kulaksizoğlu Erkan Yildirim Haris Kokotas Maria Grigoriadou Michael B Petersen Hashem Shahin Moien Kanaan Mary-Claire King Zheng-Yi Chen Susan H Blanton Xue Z Liu Stephan Zuchner Nejat Akar Mustafa Tekin

Am J Hum Genet 2010 May 6;86(5):797-804. Epub 2010 May 6.

Dr. John T. Macdonald Department of Human Genetics, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.

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May 2010

Calcium oxalate stone formation in the inner ear as a result of an Slc26a4 mutation.

Authors:
Amiel A Dror Yael Politi Hashem Shahin Danielle R Lenz Silvia Dossena Charity Nofziger Helmut Fuchs Martin Hrabé de Angelis Markus Paulmichl Steve Weiner Karen B Avraham

J Biol Chem 2010 Jul 4;285(28):21724-35. Epub 2010 May 4.

Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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July 2010

Five novel loci for inherited hearing loss mapped by SNP-based homozygosity profiles in Palestinian families.

Authors:
Hashem Shahin Tom Walsh Amal Abu Rayyan Ming K Lee Jake Higgins Diane Dickel Kristen Lewis James Thompson Carl Baker Alex S Nord Sunday Stray David Gurwitz Karen B Avraham Mary-Claire King Moien Kanaan

Eur J Hum Genet 2010 Apr 4;18(4):407-13. Epub 2009 Nov 4.

Department of Life Sciences, Bethlehem University, Bethlehem, Palestine.

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April 2010

Genomic analysis of a heterogeneous Mendelian phenotype: multiple novel alleles for inherited hearing loss in the Palestinian population.

Authors:
Tom Walsh Amal Abu Rayan Judeh Abu Sa'ed Hashem Shahin Jeanne Shepshelovich Ming K Lee Koret Hirschberg Mustafa Tekin Wa'el Salhab Karen B Avraham Mary-Claire King Moien Kanaan

Hum Genomics 2006 Jan;2(4):203-11

Department of Medicine, University of Washington, Seattle, WA, USA.

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January 2006

Mutations in a novel isoform of TRIOBP that encodes a filamentous-actin binding protein are responsible for DFNB28 recessive nonsyndromic hearing loss.

Authors:
Hashem Shahin Tom Walsh Tama Sobe Judeh Abu Sa'ed Amal Abu Rayan Eric D Lynch Ming K Lee Karen B Avraham Mary-Claire King Moein Kanaan

Am J Hum Genet 2006 Jan 21;78(1):144-52. Epub 2005 Nov 21.

Department of Life Sciences, Bethlehem University, Bethlehem.

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January 2006

From flies' eyes to our ears: mutations in a human class III myosin cause progressive nonsyndromic hearing loss DFNB30.

Authors:
Tom Walsh Vanessa Walsh Sarah Vreugde Ronna Hertzano Hashem Shahin Smadar Haika Ming K Lee Moien Kanaan Mary-Claire King Karen B Avraham

Proc Natl Acad Sci U S A 2002 May;99(11):7518-23

Department of Medicine, University of Washington, Seattle, WA 98195-7720, USA.

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May 2002

Genetics of congenital deafness in the Palestinian population: multiple connexin 26 alleles with shared origins in the Middle East.

Authors:
Hashem Shahin Tom Walsh Tama Sobe Eric Lynch Mary-Claire King Karen B Avraham Moien Kanaan

Hum Genet 2002 Mar 8;110(3):284-9. Epub 2002 Feb 8.

Department of Human Genetics and Molecular Medicine, Sackler School of Medicine, Tel Aviv University, Tel Aviv, 69978 Israel.

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March 2002