Harvest F Gu

Harvest F Gu

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Harvest F Gu

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Osteoprotegerin Promotes Liver Steatosis by Targeting the ERK-PPAR-γ-CD36 Pathway.

Diabetes 2019 Oct 10;68(10):1902-1914. Epub 2019 Jul 10.

Department of Endocrinology, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China

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http://dx.doi.org/10.2337/db18-1055DOI Listing
October 2019

Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen.

J Am Soc Nephrol 2019 Oct 19;30(10):2000-2016. Epub 2019 Sep 19.

Programs in Metabolism and Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts;

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http://dx.doi.org/10.1681/ASN.2019030218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779358PMC
October 2019

Role of bone morphogenetic protein-9 in the regulation of glucose and lipid metabolism.

FASEB J 2019 Sep 25;33(9):10077-10088. Epub 2019 Jun 25.

Key Laboratory of Diagnostic Medicine (Ministry of Education), Department of Clinical Biochemistry, College of Laboratory Medicine, Chongqing Medical University, Chongqing, China.

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http://dx.doi.org/10.1096/fj.201802544RRDOI Listing
September 2019

Increased formation of neutrophil extracellular traps is associated with gut leakage in patients with type 1 but not type 2 diabetes.

J Diabetes 2019 Aug 28;11(8):665-673. Epub 2019 Jan 28.

Minigene Pharmacy Laboratory, School of Life Science and Technology, China Pharmaceutical University, Nanjing, China.

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http://doi.wiley.com/10.1111/1753-0407.12892
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http://dx.doi.org/10.1111/1753-0407.12892DOI Listing
August 2019

Liraglutide ameliorates nonalcoholic fatty liver disease in diabetic mice via the IRS2/PI3K/Akt signaling pathway.

Diabetes Metab Syndr Obes 2019 4;12:1013-1021. Epub 2019 Jul 4.

Department of Endocrinology and Metabolism, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, People's Republic of China.

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http://dx.doi.org/10.2147/DMSO.S206867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614831PMC
July 2019

Genetic and Epigenetic Studies in Diabetic Kidney Disease.

Authors:
Harvest F Gu

Front Genet 2019 7;10:507. Epub 2019 Jun 7.

Center for Pathophysiology, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China.

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http://dx.doi.org/10.3389/fgene.2019.00507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566106PMC
June 2019

Protective Effect of the Pro582Ser Polymorphism on Severe Diabetic Retinopathy.

J Diabetes Res 2019 12;2019:2936962. Epub 2019 May 12.

Department of Endocrinology Metabolism and Diabetes, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1155/2019/2936962DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535890PMC
May 2019

Analyses of IGFBP2 DNA methylation and mRNA expression in visceral and subcutaneous adipose tissues of obese subjects.

Growth Horm IGF Res 2019 04 20;45:31-36. Epub 2019 Mar 20.

Department of Clinical Science, Danderyds Hospital, Karolinska Institutet, Danderyd, Stockholm 18288, Sweden; Department of Surgery, Ersta Hospital, Karolinska Institutet, Stockholm 11691, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ghir.2019.03.002DOI Listing
April 2019

CILP-2 is a novel secreted protein and associated with insulin resistance.

J Mol Cell Biol 2019 Mar 21. Epub 2019 Mar 21.

Department of Endocrinology, The Second Affiliated Hospital, Chongqing Medical University, Chongqing Clinical Research Center for Geriatrics, Chongqing, China.

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https://academic.oup.com/jmcb/advance-article/doi/10.1093/jm
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http://dx.doi.org/10.1093/jmcb/mjz016DOI Listing
March 2019

Protective effect of berberine on high glucose and hypoxia-induced apoptosis via the modulation of HIF-1α in renal tubular epithelial cells.

Am J Transl Res 2019 15;11(2):669-682. Epub 2019 Feb 15.

School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University Nanjing 210009, P. R. China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413295PMC
February 2019

High Circulating Alarin Levels Are Associated with Presence of Metabolic Syndrome.

Cell Physiol Biochem 2018 6;51(5):2041-2051. Epub 2018 Dec 6.

Department of Endocrinology, the Second Affiliated Hospital, Chongqing Medical University and Chongqing Clinical Research Center for Geriatrics, Chongqing,

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https://www.karger.com/Article/FullText/495823
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http://dx.doi.org/10.1159/000495823DOI Listing
January 2019

Gut ghrelin regulates hepatic glucose production and insulin signaling via a gut-brain-liver pathway.

Cell Commun Signal 2019 01 25;17(1). Epub 2019 Jan 25.

Department of Endocrinology, the Second Affiliated Hospital, Chongqing Medical University, Chongqing, 400010, China.

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https://biosignaling.biomedcentral.com/articles/10.1186/s129
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http://dx.doi.org/10.1186/s12964-019-0321-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347823PMC
January 2019

A novel role for zinc transporter 8 in the facilitation of zinc accumulation and regulation of testosterone synthesis in Leydig cells of human and mouse testicles.

Metabolism 2018 11 17;88:40-50. Epub 2018 Sep 17.

School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 210009, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2018.09.002DOI Listing
November 2018

Protective Effect of Znt7 on High Glucose-Induced Epithelial-to-Mesenchymal Transition in Renal Tubular Epithelial Cells.

Kidney Blood Press Res 2018 29;43(2):500-512. Epub 2018 Mar 29.

Department of Clinical Science, Intervention and Technology, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden.

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https://www.karger.com/Article/FullText/488697
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http://dx.doi.org/10.1159/000488697DOI Listing
October 2018

Assessment of global long interspersed nucleotide element-1 (LINE-1) DNA methylation in a longitudinal cohort of type 2 diabetes mellitus (T2DM) individuals.

Int J Clin Pract 2018 Oct 21:e13270. Epub 2018 Oct 21.

The School of Medicine and Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK.

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http://doi.wiley.com/10.1111/ijcp.13270
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http://dx.doi.org/10.1111/ijcp.13270DOI Listing
October 2018

Common Drugs for Stabilization of Renal Function in the Progression of Diabetic Nephropathy and Their Relations with Hypertension Therapy.

Curr Diabetes Rev 2018 ;14(2):149-161

Jiangsu Key Laboratory of Drug Screening, China Pharmaceutical University, Nanjing, 210009, China.

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http://dx.doi.org/10.2174/1573399813666170214112115DOI Listing
September 2018

JAZF1 ameliorates age and diet-associated hepatic steatosis through SREBP-1c -dependent mechanism.

Cell Death Dis 2018 08 28;9(9):859. Epub 2018 Aug 28.

Key Laboratory of Diagnostic Medicine (Ministry of Education) and Department of Clinical Biochemistry, College of Laboratory Medicine, Chongqing Medical University, Chongqing, P. R. China.

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http://dx.doi.org/10.1038/s41419-018-0923-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113258PMC
August 2018

Genetic, Epigenetic and Biological Effects of Zinc Transporter (SLC30A8) in Type 1 and Type 2 Diabetes.

Authors:
Harvest F Gu

Curr Diabetes Rev 2017 ;13(2):132-140

M99 Section of Renal Medicine, Department of Clinical Science, Intervention and Technologies, Karolinska Institutet, Karolinska University Hospital, Stockholm, 14157. Sweden.

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http://dx.doi.org/10.2174/1573399812666151123104540DOI Listing
May 2018

Copeptin Plasma Levels are Associated with Decline of Renal Function in Patients with Type 2 Diabetes Mellitus.

Arch Med Res 2018 01 14;49(1):36-43. Epub 2018 Apr 14.

Coordinación Médica de Investigación en Salud, Instituto Mexicano del Seguro Social, Morelia, Michoacán, México. Electronic address:

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http://dx.doi.org/10.1016/j.arcmed.2018.04.002DOI Listing
January 2018

Genetic variants of increased waist circumference in psychosis.

Psychiatr Genet 2017 12;27(6):210-218

Departments of aMolecular Medicine and Surgery, Neurogenetics Unit bNeurobiology, Care Sciences and Society, Centre for Family Medicine cClinical Neuroscience dMolecular Medicine and Surgery, Endocrine and Diabetes Unit eMedicine, Cardiovascular Medicine Unit, Karolinska Institutet fCenter for Molecular Medicine, Karolinska University Hospital Solna gDepartment of Adult Psychiatry, PRIMA Barn och Vuxenpsykiatri AB hChild and Adolescent Psychiatry Research Center, Stockholm, Sweden.

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http://dx.doi.org/10.1097/YPG.0000000000000181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662154PMC
December 2017

Circulating betatrophin is associated with insulin resistance in humans: cross-sectional and interventional studies and .

Oncotarget 2017 Nov 16;8(57):96604-96614. Epub 2017 Oct 16.

The Key Laboratory of Laboratory Medical Diagnostics in The Ministry of Education and Department of Clinical Biochemistry, College of Laboratory Medicine, Chongqing Medical University, Chongqing, China.

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http://www.oncotarget.com/fulltext/21852
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http://dx.doi.org/10.18632/oncotarget.21852DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722507PMC
November 2017

Proteasome inhibitor MG132 modulates inflammatory pain by central mechanisms in adjuvant arthritis.

Int J Rheum Dis 2017 Jan 5;20(1):25-32. Epub 2014 Apr 5.

Department of Medicine, Center for molecular medicine, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1111/1756-185X.12353DOI Listing
January 2017

Genetic, epigenetic and protein analyses of intercellular adhesion molecule 1 in Malaysian subjects with type 2 diabetes and diabetic nephropathy.

J Diabetes Complications 2015 Nov-Dec;29(8):1234-9. Epub 2015 Jul 22.

Rolf Luft Research Center for Diabetes and Endocrinology, Department of Molecular Medicine and Surgery, Karolinska University Hospital, Solna, Karolinska Institutet, Stockholm, Sweden. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10568727150027
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http://dx.doi.org/10.1016/j.jdiacomp.2015.07.004DOI Listing
September 2016

Expression of Protein Kinase C Isoforms in Pancreatic Islets and Liver of Male Goto-Kakizaki Rats, a Model of Type 2 Diabetes.

PLoS One 2015 23;10(9):e0135781. Epub 2015 Sep 23.

Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, Solna, Stockholm, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0135781PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580567PMC
June 2016

Melatonin receptor 1B gene associated with hyperglycemia in bipolar disorder.

Psychiatr Genet 2016 Jun;26(3):136-9

aNeurogenetics Unit, Department of Molecular Medicine and Surgery bDepartment of Clinical Neuroscience cEndocrine and Diabetes Unit, Department of Molecular Medicine and Surgery dCardiovascular Medicine Unit, Department of Medicine eDepartment of Neurobiology, Care Sciences and Society, Centre for Family Medicine fCentre for Psychiatric Research and Education, Karolinska Institutet gCenter for Molecular Medicine, Karolinska University Hospital Solna hChild and Adolescent Psychiatry Research Center, Stockholm iDepartment of Clinical Sciences, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1097/YPG.0000000000000131DOI Listing
June 2016

Evaluation of common variants in and the risk of type 2 diabetes and insulin resistance in Han Chinese.

Springerplus 2016 12;5(1):612. Epub 2016 May 12.

Department of Epidemiology, School of Public Health, Nanjing Medical University, 101 Longmian Avenue, Jiangning, Nanjing, 211166 China.

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http://dx.doi.org/10.1186/s40064-016-2218-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395513PMC
May 2016

Effects of sitagliptin on circulating zinc-α2-glycoprotein levels in newly diagnosed type 2 diabetes patients: a randomized trial.

Eur J Endocrinol 2016 Feb 6;174(2):147-55. Epub 2015 Nov 6.

Department of EndocrinologyThe Second Affiliated Hospital, Chongqing Medical University, Chongqing, ChinaDpartment of Endocrinology9th People's Hospital of Chongqing, Chongqong, ChinaDepartment of EndocrinologyChongqing Three Gorges Central Hospital, Chongqing, ChinaDepartment of Molecular Medicine and SurgeryKarolinska Institutet, Karolinska University Hospital, Solna, Stockholm, SwedenDepartment of PediatricsUniversity of Mississippi Medical Center, Jackson, Mississippi, USA

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http://www.eje-online.org/content/early/2015/11/06/EJE-15-06
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http://www.eje-online.org/lookup/doi/10.1530/EJE-15-0637
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http://dx.doi.org/10.1530/EJE-15-0637DOI Listing
February 2016

Genetic and biological effects of sodium-chloride cotransporter (SLC12A3) in diabetic nephropathy.

Am J Nephrol 2014 14;40(5):408-16. Epub 2014 Nov 14.

Rolf Luft Research Center for Diabetes and Endocrinology, Department of Molecular Medicine and Surgery, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1159/000368916DOI Listing
August 2015

Evaluation of Antidiabetic Effects of the Traditional Medicinal Plant Gynostemma pentaphyllum and the Possible Mechanisms of Insulin Release.

Evid Based Complement Alternat Med 2015 23;2015:120572. Epub 2015 Jun 23.

Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, SE-171 76 Stockholm, Sweden.

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http://downloads.hindawi.com/journals/ecam/2015/120572.pdf
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http://www.hindawi.com/journals/ecam/2015/120572/
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http://dx.doi.org/10.1155/2015/120572DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493304PMC
July 2015

Increased DNA methylation of the SLC30A8 gene promoter is associated with type 2 diabetes in a Malay population.

Clin Epigenetics 2015 18;7:30. Epub 2015 Mar 18.

Department of Molecular Medicine and Surgery, Rolf Luft Research Center for Diabetes and Endocrinology, M1:03 Karolinska University Hospital, Karolinska Institutet, Stockholm, Se-17176 Sweden.

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http://dx.doi.org/10.1186/s13148-015-0049-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365519PMC
March 2015

Evaluation of the association of plasma pentraxin 3 levels with type 2 diabetes and diabetic nephropathy in a Malay population.

J Diabetes Res 2013 20;2013:298019. Epub 2013 Nov 20.

Rolf Luft Research Center for Diabetes and Endocrinology, Department of Molecular Medicine and Surgery, Karolinska University Hospital, Solna, Karolinska Institutet, SE-17176 Stockholm, Sweden.

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http://www.hindawi.com/journals/jdr/2013/298019/
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http://dx.doi.org/10.1155/2013/298019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854091PMC
June 2014

Epigenetic analyses of the insulin-like growth factor binding protein 1 gene in type 1 diabetes and diabetic nephropathy.

Clin Epigenetics 2014 30;6(1):10. Epub 2014 May 30.

Rolf Luft Research Center for Diabetes and Endocrinology, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden ; Department of Endocrinology, Metabolism and Diabetes, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1186/1868-7083-6-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046502PMC
June 2014

FTO genetic variants and risk of obesity and type 2 diabetes: a meta-analysis of 28,394 Indians.

Obesity (Silver Spring) 2014 Mar 20;22(3):964-70. Epub 2013 Sep 20.

Department of Molecular Medicine and Surgery Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Stockholm, Sweden; Department of Endocrinology Diabetes and Metabolism, Christian Medical College, Vellore, Tamil Nadu, India.

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http://dx.doi.org/10.1002/oby.20606DOI Listing
March 2014

Antidiabetic Effect of Oral Borapetol B Compound, Isolated from the Plant Tinospora crispa, by Stimulating Insulin Release.

Evid Based Complement Alternat Med 2013 10;2013:727602. Epub 2013 Nov 10.

Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, 171 76 Stockholm, Sweden ; Department of Diabetes, Cardiovascular, Diabetes and Nutrition Research Centre, Institute for Medical Research, 50588 Jalan Pahang, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1155/2013/727602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3844206PMC
December 2013

Evaluation of IGFBP-7 DNA methylation changes and serum protein variation in Swedish subjects with and without type 2 diabetes.

Clin Epigenetics 2013 Nov 4;5(1):20. Epub 2013 Nov 4.

Rolf Luft Research Center for Diabetes and Endocrinology, Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, Stockholm SE-171 76, Sweden.

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http://dx.doi.org/10.1186/1868-7083-5-20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817812PMC
November 2013

Increased DNA methylation levels of the insulin-like growth factor binding protein 1 gene are associated with type 2 diabetes in Swedish men.

Clin Epigenetics 2013 Nov 19;5(1):21. Epub 2013 Nov 19.

Rolf Luft Research Center for Diabetes and Endocrinology, Department of Molecular Medicine and Surgery, Karolinska Institute, Department of Endocrinology, Karolinska University Hospital, Stockholm SE-17176, Sweden.

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http://clinicalepigeneticsjournal.biomedcentral.com/articles
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http://dx.doi.org/10.1186/1868-7083-5-21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843565PMC
November 2013

Genetic association of adrenergic receptor alpha 2A with obesity and type 2 diabetes.

Obesity (Silver Spring) 2013 Aug 11;21(8):1720-5. Epub 2013 Jun 11.

Department of Molecular Medicine and Surgery, Rolf Luft Center for Diabetes Research, Karolinska Institutet, Karolinska University Hospital (Solna), Stockholm, Sweden.

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http://dx.doi.org/10.1002/oby.20162DOI Listing
August 2013

Prediction of IVF/ICSI outcome based on the follicular output rate.

Reprod Biomed Online 2013 Aug 4;27(2):147-53. Epub 2013 May 4.

Center for Reproductive Medicine, Provincial Hospital Affiliated to Shandong University, 250021 Jinan, China.

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https://linkinghub.elsevier.com/retrieve/pii/S14726483130023
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http://dx.doi.org/10.1016/j.rbmo.2013.04.012DOI Listing
August 2013

Labisia pumila Upregulates Peroxisome Proliferator-Activated Receptor Gamma Expression in Rat Adipose Tissues and 3T3-L1 Adipocytes.

Adv Pharmacol Sci 2013 7;2013:808914. Epub 2013 Jul 7.

Cardiovascular, Diabetes and Nutrition Research Centre, Institute for Medical Research, 50588 Jalan Pahang, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1155/2013/808914DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723002PMC
August 2013

Impact of the hypoxia-inducible factor-1 α (HIF1A) Pro582Ser polymorphism on diabetes nephropathy.

Diabetes Care 2013 Feb 18;36(2):415-21. Epub 2012 Sep 18.

Rolf Luft Research Center for Diabetes and Endocrinology, Department of Molecular Medicine and Surgery, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.2337/dc12-1125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554309PMC
February 2013

IGF2BP2 and IGF2 genetic effects in diabetes and diabetic nephropathy.

J Diabetes Complications 2012 Sep-Oct;26(5):393-8. Epub 2012 Jul 4.

Department of Molecular Medicine and Surgery, Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.jdiacomp.2012.05.012DOI Listing
January 2013

Consumption of whole grain reduces risk of deteriorating glucose tolerance, including progression to prediabetes.

Am J Clin Nutr 2013 Jan 12;97(1):179-87. Epub 2012 Dec 12.

Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.3945/ajcn.112.045583DOI Listing
January 2013

Association of intercellular adhesion molecule 1 (ICAM1) with diabetes and diabetic nephropathy.

Front Endocrinol (Lausanne) 2012 22;3:179. Epub 2013 Jan 22.

M1:03 Rolf Luft Center for Diabetes and Endocrinology Research, Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital Stockholm, Sweden.

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http://journal.frontiersin.org/article/10.3389/fendo.2012.00
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http://dx.doi.org/10.3389/fendo.2012.00179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551242PMC
January 2013

Evaluation of the association between the ADRA2A genetic polymorphisms and type 2 diabetes in a Chinese Han population.

Genet Test Mol Biomarkers 2012 Dec;16(12):1424-7

National Laboratory of Medical Molecular Biology, Peking Union Medical College, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Beijing, China.

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http://dx.doi.org/10.1089/gtmb.2012.0189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501114PMC
December 2012

Associations of variants in FTO and near MC4R with obesity traits in South Asian Indians.

Obesity (Silver Spring) 2012 Nov 16;20(11):2268-77. Epub 2012 Mar 16.

Rolf Luft Research Center for Diabetes and Endocrinology, Department of Molecular Medicine & Surgery, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1038/oby.2012.64DOI Listing
November 2012

Genetic association studies in diabetic nephropathy.

Curr Diabetes Rev 2012 Sep;8(5):336-44

Rolf Luft Research Center for Diabetes and Endocrinology, Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, Stockholm, SE-17176 Sweden.

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http://dx.doi.org/10.2174/157339912802083522DOI Listing
September 2012

New susceptibility loci associated with kidney disease in type 1 diabetes.

PLoS Genet 2012 Sep 20;8(9):e1002921. Epub 2012 Sep 20.

Folkhälsan Institute of Genetics, Folkhälsan Research Center, Biomedicum Helsinki, Helsinki, Finland.

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http://pure.qub.ac.uk/portal/files/2407268/New_Susceptibilit
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http://dx.plos.org/10.1371/journal.pgen.1002921
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http://dx.doi.org/10.1371/journal.pgen.1002921DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447939PMC
September 2012

Labisia pumila extract down-regulates hydroxysteroid (11-beta) dehydrogenase 1 expression and corticosterone levels in ovariectomized rats.

J Nat Med 2012 Apr 11;66(2):257-64. Epub 2011 Aug 11.

Diabetes and Endocrine Unit, Cardiovascular, Diabetes and Nutrition Research Centre, Institute for Medical Research, Jalan Pahang, 50588 Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1007/s11418-011-0575-1DOI Listing
April 2012

Genetic and functional effects of membrane metalloendopeptidase on diabetic nephropathy development.

Am J Nephrol 2011 22;34(5):483-90. Epub 2011 Oct 22.

Rolf Luft Center for Diabetes Research, Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1159/000333006DOI Listing
April 2012

Evaluation of Sox2 genetic effect on the development of type 2 diabetes.

Gene 2011 Oct 26;486(1-2):94-6. Epub 2011 Jul 26.

Rolf Luft Center for Diabetes Research, Department of Molecular Medicine and Surgery, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.gene.2011.07.014DOI Listing
October 2011

Evaluation of the association between GHR exon 3 polymorphism and polycystic ovary syndrome among Han Chinese women.

Growth Horm IGF Res 2011 Oct 5;21(5):248-51. Epub 2011 Aug 5.

Central laboratory, Provincial Hospital Affiliated to Shandong University, Jinan, People's Republic of China.

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https://linkinghub.elsevier.com/retrieve/pii/S10966374110007
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http://dx.doi.org/10.1016/j.ghir.2011.07.002DOI Listing
October 2011

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes.

Authors:
Rona J Strawbridge Josée Dupuis Inga Prokopenko Adam Barker Emma Ahlqvist Denis Rybin John R Petrie Mary E Travers Nabila Bouatia-Naji Antigone S Dimas Alexandra Nica Eleanor Wheeler Han Chen Benjamin F Voight Jalal Taneera Stavroula Kanoni John F Peden Fabiola Turrini Stefan Gustafsson Carina Zabena Peter Almgren David J P Barker Daniel Barnes Elaine M Dennison Johan G Eriksson Per Eriksson Elodie Eury Lasse Folkersen Caroline S Fox Timothy M Frayling Anuj Goel Harvest F Gu Momoko Horikoshi Bo Isomaa Anne U Jackson Karen A Jameson Eero Kajantie Julie Kerr-Conte Teemu Kuulasmaa Johanna Kuusisto Ruth J F Loos Jian'an Luan Konstantinos Makrilakis Alisa K Manning María Teresa Martínez-Larrad Narisu Narisu Maria Nastase Mannila John Ohrvik Clive Osmond Laura Pascoe Felicity Payne Avan A Sayer Bengt Sennblad Angela Silveira Alena Stancáková Kathy Stirrups Amy J Swift Ann-Christine Syvänen Tiinamaija Tuomi Ferdinand M van 't Hooft Mark Walker Michael N Weedon Weijia Xie Björn Zethelius Halit Ongen Anders Mälarstig Jemma C Hopewell Danish Saleheen John Chambers Sarah Parish John Danesh Jaspal Kooner Claes-Göran Ostenson Lars Lind Cyrus C Cooper Manuel Serrano-Ríos Ele Ferrannini Tom J Forsen Robert Clarke Maria Grazia Franzosi Udo Seedorf Hugh Watkins Philippe Froguel Paul Johnson Panos Deloukas Francis S Collins Markku Laakso Emmanouil T Dermitzakis Michael Boehnke Mark I McCarthy Nicholas J Wareham Leif Groop François Pattou Anna L Gloyn George V Dedoussis Valeriya Lyssenko James B Meigs Inês Barroso Richard M Watanabe Erik Ingelsson Claudia Langenberg Anders Hamsten Jose C Florez

Diabetes 2011 Oct 26;60(10):2624-34. Epub 2011 Aug 26.

Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital Solna, Stockholm, Sweden.

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http://dx.doi.org/10.2337/db11-0415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178302PMC
October 2011

Evaluation of the association between the AC3 genetic polymorphisms and obesity in a Chinese Han population.

PLoS One 2010 Nov 4;5(11):e13851. Epub 2010 Nov 4.

Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, People's Republic of China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0013851PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2973974PMC
November 2010

Evaluation of the association between the CYP19 Tetranucleotide (TTTA)n polymorphism and polycystic ovarian syndrome(PCOS) in Han Chinese women.

Neuro Endocrinol Lett 2010 ;31(3):370-4

Reproductive Medical Center, Yantai Yuhuangding Hospital, Affiliated hospital of Medical College of Qingdao University, Yantai, P.R. China.

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October 2010

Effects of MCF2L2, ADIPOQ and SOX2 genetic polymorphisms on the development of nephropathy in type 1 Diabetes Mellitus.

BMC Med Genet 2010 Jul 28;11:116. Epub 2010 Jul 28.

Rolf Luft Center for Diabetes Research, Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, Solna, Stockholm, Sweden.

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http://dx.doi.org/10.1186/1471-2350-11-116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919463PMC
July 2010

The Common FTO Genetic Polymorphism rs9939609 is Associated with Increased BMI in Type 1 Diabetes but not with Diabetic Nephropathy.

Biomark Insights 2010 Apr 27;5:29-32. Epub 2010 Apr 27.

Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, Solna, Stockholm, Sweden. Email:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867633PMC
http://dx.doi.org/10.4137/bmi.s4599DOI Listing
April 2010

Family-based association study of the MCF2L2 gene and polycystic ovary syndrome.

Gynecol Obstet Invest 2009 31;68(3):171-3. Epub 2009 Jul 31.

Center for Reproductive Medicine, Provincial Hospital, Shandong University, Jinan, China.

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http://dx.doi.org/10.1159/000231520DOI Listing
February 2010

Evaluation of the association between the PPARGC1A genetic polymorphisms and type 2 diabetes in Han Chinese population.

Diabetes Res Clin Pract 2009 Dec 13;86(3):168-72. Epub 2009 Oct 13.

National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, PR China.

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http://dx.doi.org/10.1016/j.diabres.2009.09.020DOI Listing
December 2009

SOX2 has gender-specific genetic effects on diabetic nephropathy in samples from patients with type 1 diabetes mellitus in the GoKinD study.

Gend Med 2009 Dec;6(4):555-64

Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital Solna, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.genm.2009.11.001DOI Listing
December 2009

Biomarkers of adiponectin: plasma protein variation and genomic DNA polymorphisms.

Authors:
Harvest F Gu

Biomark Insights 2009 Oct 13;4:123-33. Epub 2009 Oct 13.

Department of Molecular Medicine and Surgery, Karolinska Hospital, Karolinska Institutet, Stockholm, Sweden. Email:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796863PMC
http://dx.doi.org/10.4137/bmi.s3453DOI Listing
October 2009

A single nucleotide polymorphism alters the sequence of SP1 binding site in the adiponectin promoter region and is associated with diabetic nephropathy among type 1 diabetic patients in the Genetics of Kidneys in Diabetes Study.

J Diabetes Complications 2009 Jul-Aug;23(4):265-72. Epub 2008 Jul 3.

Department of Molecular Medicine and Surgery, Rolf Luft Center for Diabetes Research, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.

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http://linkinghub.elsevier.com/retrieve/pii/S105687270800053
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http://dx.doi.org/10.1016/j.jdiacomp.2008.05.004DOI Listing
September 2009

Evaluation of genetic association and expression reduction of TRPC1 in the development of diabetic nephropathy.

Am J Nephrol 2009 19;29(3):244-51. Epub 2008 Sep 19.

Rolf Luft Center for Diabetes Research, Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, Solna, Stockholm, Sweden.

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https://www.karger.com/Article/FullText/157627
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http://dx.doi.org/10.1159/000157627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698220PMC
June 2009

Evaluation of association between the CYP11alpha promoter pentannucleotide (TTTTA)n polymorphism and polycystic ovarian syndrome among Han Chinese women.

Neuro Endocrinol Lett 2009 Mar;30(1):56-60

Reproductive Medical Center, Yantai Yuhuangding Hospital, Medical College of Qingdao University, Yantai, China.

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March 2009

Apolipoprotein M promoter polymorphisms alter promoter activity and confer the susceptibility to the development of type 1 diabetes.

Clin Biochem 2009 Jan 30;42(1-2):17-21. Epub 2008 Oct 30.

National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, 5 Dongdan 3 Tiao, Beijing 100005, PR China.

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http://dx.doi.org/10.1016/j.clinbiochem.2008.10.008DOI Listing
January 2009

Labisia pumila extract regulates body weight and adipokines in ovariectomized rats.

Maturitas 2009 Jan 2;62(1):91-7. Epub 2008 Dec 2.

Department of Molecular Medicine and Surgery, M1:03, Karolinska Institutet, Karolinska University Hospital, SE-171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.maturitas.2008.10.004DOI Listing
January 2009

Evidence that the gene encoding insulin degrading enzyme influences human lifespan.

Hum Mol Genet 2008 Aug 30;17(15):2370-8. Epub 2008 Apr 30.

Department of Medical Epidemiology and Biostatistics, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1093/hmg/ddn137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2574758PMC
August 2008

Evaluation of the association between the common E469K polymorphism in the ICAM-1 gene and diabetic nephropathy among type 1 diabetic patients in GoKinD population.

BMC Med Genet 2008 May 27;9:47. Epub 2008 May 27.

Rolf Luft Center for Diabetes Research, Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1186/1471-2350-9-47DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2424038PMC
May 2008

Genetic variation and association analyses of the nuclear respiratory factor 1 (nRF1) gene in Chinese patients with type 2 diabetes.

Diabetes 2008 Mar 10;57(3):777-82. Epub 2007 Dec 10.

National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.2337/db07-0008DOI Listing
March 2008

Association of +45G15G(T/G) and +276(G/T) polymorphisms in the ADIPOQ gene with polycystic ovary syndrome among Han Chinese women.

Eur J Endocrinol 2008 Feb;158(2):255-60

Reproductive Medical Center, The Affiliated Yantai Yuhuangding Hospital of Qingdao University Medical College, Yantai, People's Republic of China.

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https://eje.bioscientifica.com/view/journals/eje/158/2/255.x
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http://dx.doi.org/10.1530/EJE-07-0576DOI Listing
February 2008

Distribution of neuropeptide Y Leu7Pro polymorphism in patients with type 1 diabetes and diabetic nephropathy among Swedish and American populations.

Eur J Endocrinol 2007 Nov;157(5):641-5

Department of Molecular Medicine and Surgery, L6:B2, Karolinska Institutet, Rolf Luft Center for Diabetes Research, Karolinska University Hospital, SE-171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1530/EJE-07-0354DOI Listing
November 2007

Genetic variation in receptor protein tyrosine phosphatase sigma is associated with type 2 diabetes in Swedish Caucasians.

Eur J Endocrinol 2007 Oct;157(4):459-64

Department of Molecular Medicine and Surgery, Karolinska Institutet, Rolf Luft Center for Diabetes Research, Karolinska University Hospital Solna, 171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1530/EJE-07-0114DOI Listing
October 2007

Novel non-synonymous mutation in the transforming growth factor beta binding protein-like (TB) domain of the fibrillin-1 (FBN1) gene in a Han Chinese family with Marfan syndrome (MFS).

Neuro Endocrinol Lett 2007 Oct;28(5):629-32

Center for Reproductive Medicine, Shandong Provincial Hospital, Shandong University, Jinan, China.

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October 2007

Genetic association analysis of the adiponectin polymorphisms in type 1 diabetes with and without diabetic nephropathy.

J Diabetes Complications 2007 Jan-Feb;21(1):28-33

Rolf Luft Center for Diabetes Research, Department of Molecular Medicine and Surgery, Karolinska Institute, SE-171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.jdiacomp.2006.03.002DOI Listing
March 2007

Single nucleotide polymorphisms in the proximal promoter region of apolipoprotein M gene (apoM) confer the susceptibility to development of type 2 diabetes in Han Chinese.

Diabetes Metab Res Rev 2007 Jan;23(1):21-5

National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, PR China.

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http://dx.doi.org/10.1002/dmrr.641DOI Listing
January 2007

Improvement of the sensitivity and resolution of PCR-SSCP analysis with optimized primer concentrations in PCR products.

J Genet 2006 Dec;85(3):233-5

National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, China.

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http://dx.doi.org/10.1007/bf02935339DOI Listing
December 2006

Quantitative trait loci near the insulin-degrading enzyme (IDE) gene contribute to variation in plasma insulin levels.

Diabetes 2004 Aug;53(8):2137-42

Department of Molecular Medicine, Rolf Luft Center for Diabetes Research, Karolinska Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.2337/diabetes.53.8.2137DOI Listing
August 2004

Single nucleotide polymorphisms in the proximal promoter region of the adiponectin (APM1) gene are associated with type 2 diabetes in Swedish caucasians.

Diabetes 2004 Feb;53 Suppl 1:S31-5

Rolf Luft Center for Diabetes Research, Department of Molecular Medicine, Karolinska Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.2337/diabetes.53.2007.s31DOI Listing
February 2004

Genetic variation in a haplotype block spanning IDE influences Alzheimer disease.

Hum Mutat 2003 Nov;22(5):363-71

Center for Genomics and Bioinformatics, Karolinska Institute, Stockholm, Sweden.

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http://doi.wiley.com/10.1002/humu.10282
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November 2003

Genetic variation screening and association studies of the adenylate cyclase activating polypeptide 1 (ADCYAP1) gene in patients with type 2 diabetes.

Authors:
Harvest F Gu

Hum Mutat 2002 May;19(5):572-3

Center for Genomics and Bioinformatics (CGB), Karolinska Institute, Stockholm, Sweden.

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http://doi.wiley.com/10.1002/humu.9034
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http://dx.doi.org/10.1002/humu.9034DOI Listing
May 2002