Haruhiko Osawa

Haruhiko Osawa

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Haruhiko Osawa

Haruhiko Osawa

Publications by authors named "Haruhiko Osawa"

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94Publications

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Small Dense Low-Density Lipoprotein Cholesterol and the Risk of Coronary Heart Disease in a Japanese Community.

J Atheroscler Thromb 2019 Nov 11. Epub 2019 Nov 11.

Department of Epidemiology and Public Health, Graduate School of Medical Sciences, Kyushu University.

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http://dx.doi.org/10.5551/jat.51961DOI Listing
November 2019

Effect of non-surgical periodontal therapy on insulin resistance and insulin sensitivity among individuals with borderline diabetes: A randomized controlled trial.

J Dent 2019 Jun 12;85:18-24. Epub 2019 Apr 12.

Department of Public Health and Epidemiology, Faculty of Medicine, Oita University 1-1 Idaigaoka, Hasama-machi, Yufu-shi Oita, 879-5593, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jdent.2019.04.005DOI Listing
June 2019

Seasonal Variation in Severe Glucose-lowering Drug-induced Hypoglycemia in Patients with Type 2 Diabetes.

Intern Med 2019 Apr 10;58(8):1067-1072. Epub 2019 Jan 10.

Department of Medicine, Diabetes, Metabolism and Endocrinology, Matsuyama Red Cross Hospital, Japan.

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http://dx.doi.org/10.2169/internalmedicine.1360-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522416PMC
April 2019

Associations of snoring frequency with blood pressure among the lean Japanese population: the Toon Health Study.

J Hum Hypertens 2019 Jan 8. Epub 2019 Jan 8.

Department of Public Health and Epidemiology, Faculty of Medicine, Oita University, Oita, Oita, 879-5593, Japan.

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http://dx.doi.org/10.1038/s41371-018-0148-9DOI Listing
January 2019

Association Between Heart Rate Variability and Home Blood Pressure: The Toon Health Study.

Am J Hypertens 2018 09;31(10):1120-1126

Department of Public Health, Juntendo University Graduate School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1093/ajh/hpy100DOI Listing
September 2018

Towards precision medicine for type 2 diabetes.

Authors:
Haruhiko Osawa

Diabetol Int 2017 Aug 30;8(3):243. Epub 2017 Jun 30.

Department of Diabetes and Molecular Genetics, Ehime University Graduate School of Medicine, Toon, Ehime 791-0295 Japan.

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http://dx.doi.org/10.1007/s13340-017-0324-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224894PMC
August 2017

[Rapid Identification Method Positive Blood Culture Bottles with MALDI Biotyper].

Rinsho Biseibutshu Jinsoku Shindan Kenkyukai Shi 2015 ;26(1):13-9

Department of Clinical Laboratory, Ehime University Hospital.

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June 2016

The impact of masticatory ability as evaluated by salivary flow rates on obesity in Japanese: The Toon health study.

Obesity (Silver Spring) 2015 Jun 9;23(6):1296-302. Epub 2015 May 9.

Department of Public Health, Juntendo University Graduate School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo, Japan.

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http://dx.doi.org/10.1002/oby.21071DOI Listing
June 2015

Association of hematological parameters with insulin resistance, insulin sensitivity, and asymptomatic cerebrovascular damage: the J-SHIP and Toon Health Study.

Clin Hemorheol Microcirc 2013 ;55(3):297-311

Department of Geriatric Medicine, Ehime University Graduate School of Medicine, Toon City, Japan Division of Anti-aging and Genetics, Ehime University Proteo-Medicine Research Center, Toon City, Japan.

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http://dx.doi.org/10.3233/CH-2012-1634DOI Listing
October 2014

Sleep-related intermittent hypoxemia and glucose intolerance: a community-based study.

Sleep Med 2014 Oct 27;15(10):1212-8. Epub 2014 Jun 27.

Department of Medicine, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD, USA.

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http://dx.doi.org/10.1016/j.sleep.2014.05.027DOI Listing
October 2014

Insulin administration may trigger type 1 diabetes in Japanese type 2 diabetes patients with type 1 diabetes high-risk HLA class II and the insulin gene VNTR genotype.

J Clin Endocrinol Metab 2014 Sep 27;99(9):E1793-7. Epub 2014 Jun 27.

Department of Diabetes and Molecular Genetics (W.N., R.K., H.On., H.Os., H.M.), Ehime University Graduate School of Medicine, To-on, Ehime 791-0295, Japan; Department of Internal Medicine (M.N.), Kokogawa W City Hospital, Hyogo 675-8611, Japan; Department of Metabolic Medicine (A.I.), Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan; Department of Internal Medicine (I) (T.H.), Osaka Medical College, Osaka 569-8686, Japan; University of Tsukuba (J.O.), Ibaraki, Japan; 6) Division of Diabetes (K.T.), Department of Internal Medicine, Kurashiki Central Hospital, Kurashiki 710-8602, Japan; Department of Diabetes (T.S.), Kochi Takasu Hospital, Kochi 781-5103, Japan; Sumitomo Hospital (Y.Y.), Osaka 530-0005, Japan; Diabetes Research Center (D.C.), National Center for Global Health and Medicine, Tokyo 162-8655, Japan; Department of Metabolism/Diabetes and Clinical Nutrition (E.K.), Nagasaki University Hospital, Nagasaki 852-8501, Japan; and Shiraishi Hospital Diabetes Center (H.M.), Imabari, Ehime 794-0041, Japan.

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http://dx.doi.org/10.1210/jc.2014-1759DOI Listing
September 2014

[Staphylococcal cassette chromosome mec types and antimicrobial susceptibilities of methicillin-resistant Staphylococcus aureus isolated from our hospital].

Rinsho Biseibutshu Jinsoku Shindan Kenkyukai Shi 2013 ;23(2):61-7

Department of Clinical Laboratory, Ehime University Hospital.

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September 2013

High frequency of HLA B62 in fulminant type 1 diabetes with the drug-induced hypersensitivity syndrome.

J Clin Endocrinol Metab 2012 Dec 15;97(12):E2277-81. Epub 2012 Oct 15.

Department of Molecular and Genetic Medicine, Ehime University Graduate School of Medicine, To-on, Ehime, 791-0295 Japan.

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http://dx.doi.org/10.1210/jc.2012-2054DOI Listing
December 2012

Relatively lower central aortic pressure in patients with impaired insulin sensitivity and resistance: the Toon Health Study.

J Hypertens 2011 Oct;29(10):1948-54

Department of Basic Medical Research and Education, Ehime University Proteo-Medicine Research Center, Ehime, Japan.

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http://dx.doi.org/10.1097/HJH.0b013e32834abd06DOI Listing
October 2011

Circulating resistin is increased with decreasing renal function in a general Japanese population: the Hisayama Study.

Nephrol Dial Transplant 2010 Oct 25;25(10):3236-40. Epub 2010 Mar 25.

Department of Environmental Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1093/ndt/gfq155DOI Listing
October 2010

Replication study of candidate genes associated with type 2 diabetes based on genome-wide screening.

Diabetes 2009 Feb 25;58(2):493-8. Epub 2008 Nov 25.

Department of Basic Medical Research and Education, Ehime University Graduate School of Medicine, Toon City, Ehime, Japan.

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http://dx.doi.org/10.2337/db07-1785DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628625PMC
February 2009

[Role of resistin in insulin resistance].

Rinsho Byori 2008 Aug;56(8):698-704

Department of Molecular and Genetic Medicine, Ehime University Graduate School of Medicine, Toon 791-0295.

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August 2008

Serum resistin is positively correlated with the accumulation of metabolic syndrome factors in type 2 diabetes.

Clin Endocrinol (Oxf) 2008 Jul 1;69(1):74-80. Epub 2008 Jul 1.

Department of Molecular and Genetic Medicine, Ehime University Graduate School of Medicine, Ehime Prefectural Hospital, Ehime, Japan.

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http://doi.wiley.com/10.1111/j.1365-2265.2007.03154.x
Publisher Site
http://dx.doi.org/10.1111/j.1365-2265.2007.03154.xDOI Listing
July 2008

Insulin administration may trigger pancreatic beta-cell destruction in patients with type 2 diabetes.

Diabetes Res Clin Pract 2008 Feb 24;79(2):220-9. Epub 2007 Oct 24.

Department of Molecular and Genetic Medicine, Ehime University Graduate School of Medicine, Toon-shi, Ehime 791-0295, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S016882270700462
Publisher Site
http://dx.doi.org/10.1016/j.diabres.2007.08.031DOI Listing
February 2008

Resistin, glomerular filtration rate, and insulin resistance.

Hypertension 2008 Feb 24;51(2):e11; author reply e12. Epub 2007 Dec 24.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.107.102046DOI Listing
February 2008

Hyperresistinemia is associated with coexistence of hypertension and type 2 diabetes.

Hypertension 2008 Feb 7;51(2):534-9. Epub 2008 Jan 7.

Department of Molecular and Genetic Medicine, Ehime University Graduate School of Medicine, Toon, Ehime 791-0295, Japan.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.107.103077DOI Listing
February 2008

Serum resistin is reduced by glucose and meal loading in healthy human subjects.

Metabolism 2008 Feb;57(2):149-56

Department of Molecular and Genetic Medicine, Ehime University Graduate School of Medicine, Toon, Ehime 791-0295, Japan.

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http://dx.doi.org/10.1016/j.metabol.2007.08.018DOI Listing
February 2008

No association between INSIG2 Gene rs7566605 polymorphism and being overweight in Japanese population.

Obesity (Silver Spring) 2008 Jan;16(1):211-5

Department of Basic Medical Research, Education, Ehime University Graduate School of Medicine, Ehime, Japan.

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http://dx.doi.org/10.1038/oby.2007.25DOI Listing
January 2008

[Clinical significance of small, dense LDL cholesterol in patients with hyperlipidemia and type 2 diabetes].

Rinsho Byori 2007 Aug;55(8):705-11

Department of Clinical Support, Ehime University School of Medicine, Toon.

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August 2007

A case of insulin-induced localized lobular panniculitis with evidence for the phagocytosis of insulin by histiocytes.

Endocr J 2007 Jun 25;54(3):477-80. Epub 2007 Apr 25.

Department of Diabetes & Endocrinology, Ehime Prefectural Central Hospital, Matsuyama, Japan.

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http://dx.doi.org/10.1507/endocrj.k06-173DOI Listing
June 2007

Serum resistin is associated with the severity of microangiopathies in type 2 diabetes.

Biochem Biophys Res Commun 2007 Apr 5;355(2):342-6. Epub 2007 Feb 5.

Department of Molecular and Genetic Medicine, Ehime, University Graduate School of Medicine, Toon, Ehime 791-0295, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2007.01.144DOI Listing
April 2007

[Clinical significance of serum-glycated apolipoprotein B measured by the digestion LDL sediment fraction with protease].

Rinsho Byori 2006 Jun;54(6):583-8

Central Laboratory Department, Ehime University School of Medicine, Toon.

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June 2006

[Genetic testing and gene-based testing for type 2 diabetes].

Nihon Rinsho 2005 Dec;63 Suppl 12:295-300

Department of Laboratory Medicine, Ehime University School of Medicine.

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December 2005

A newly identified 50 kDa protein, which is associated with phosphodiesterase 3B, is phosphorylated by insulin in rat adipocytes.

Biochem Biophys Res Commun 2005 Nov 3;337(3):976-82. Epub 2005 Oct 3.

Department of Laboratory Medicine, Ehime University School of Medicine, Toon-shi, Ehime 791-0295, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2005.09.144DOI Listing
November 2005

Resistin SNP-420 determines its monocyte mRNA and serum levels inducing type 2 diabetes.

Biochem Biophys Res Commun 2005 Sep;335(2):596-602

Department of Laboratory Medicine, Ehime University School of Medicine, Shitsukawa, Toon, Ehime 791-0295, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2005.07.122DOI Listing
September 2005

A nonsense mutation in the Arg345 of the insulin receptor gene in a Japanese type A insulin-resistant patient.

Endocr J 2005 Aug;52(4):499-504

Department of Diabetology and Clinical Laboratory Medicine, National University Corporation, Ehime University School of Medicine, Ehime.

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http://dx.doi.org/10.1507/endocrj.52.499DOI Listing
August 2005

A simple precipitation method for measuring sialic acid in apolipoprotein B-containing lipoproteins in plasma.

Ann Clin Biochem 2005 Jul;42(Pt 4):298-300

Central Laboratory Department, Ehime University School of Medicine, Toon City, 791-0295, Ehime Prefecture, Japan.

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http://dx.doi.org/10.1258/0004563054255614DOI Listing
July 2005

[Convenient assay for glycated apolipoprotein B using protease].

Rinsho Byori 2005 Jun;53(6):504-8

Department of Clinical Laboratory, Ehime University School of Medicine, Toon, Ehime-pref 791-0295.

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June 2005

[Combined use of fasting plasma glucose and HbA1c (as a screening test)].

Nihon Rinsho 2005 Feb;63 Suppl 2:390-3

Department of Laboratory Medicine (Diabetes), Ehime University School of Medicine.

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February 2005

Identification of the insulin-regulated interaction of phosphodiesterase 3B with 14-3-3 beta protein.

Diabetes 2002 Dec;51(12):3362-7

Department of Laboratory Medicine, Ehime University School of Medicine, Shigenobu, Ehime 791-0295, Japan.

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http://dx.doi.org/10.2337/diabetes.51.12.3362DOI Listing
December 2002

Differential regulation of gene expression and insulin-induced activation of phosphodiesterase 3B in adipocytes of lean insulin-resistant IRS-1 (-/-) mice.

Diabetes Res Clin Pract 2002 Nov;58(2):79-85

Department of Laboratory Medicine, Ehime University School of Medicine, Shigenobu, Ehime 791-0295, Japan.

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http://dx.doi.org/10.1016/s0168-8227(02)00132-8DOI Listing
November 2002

[Current status of study for type 2 diabetes susceptibility genes].

Nihon Rinsho 2002 Aug;60 Suppl 8:271-6

Department of Laboratory Medicine, Ehime University School of Medicine.

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August 2002