Haruhiko Koseki

Haruhiko Koseki

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Haruhiko Koseki

Publications by authors named "Haruhiko Koseki"

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Chromatin and epigenetics in development: a Special Issue.

Development 2019 Oct 10;146(19). Epub 2019 Oct 10.

Institute of Epigenetics and Stem Cells (IES), Helmholtz Zentrum München, Marchioninistraße 25, D-81377 München, Germany.

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http://dx.doi.org/10.1242/dev.185025DOI Listing
October 2019

PRC2.1 and PRC2.2 Synergize to Coordinate H3K27 Trimethylation.

Mol Cell 2019 Sep 5. Epub 2019 Sep 5.

Smurfit Institute of Genetics, Trinity College Dublin, Dublin 2, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2019.08.012DOI Listing
September 2019

Polycomb Repressive Complex 1 Controls Maintenance of Fungiform Papillae by Repressing Sonic Hedgehog Expression.

Cell Rep 2019 Jul;28(1):257-266.e5

Black Family Stem Cell Institute, The Tisch Cancer Institute, Department of Cell, Developmental, and Regenerative Biology, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.06.011DOI Listing
July 2019

Np95/Uhrf1 regulates tumor suppressor gene expression of neural stem/precursor cells, contributing to neurogenesis in the adult mouse brain.

Neurosci Res 2019 Jun 31;143:31-43. Epub 2018 May 31.

Stem Cell Biology and Medicine, Department of Stem Cell Biology and Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.neures.2018.05.007DOI Listing
June 2019

Live Imaging of Xist RNA.

Methods Mol Biol 2018 ;1861:67-72

Laboratory for Developmental Genetics, Center for Integrative Medical Sciences, RIKEN Yokohama Institute, Yokohama, Japan.

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http://dx.doi.org/10.1007/978-1-4939-8766-5_6DOI Listing
June 2019

Synergy between Variant PRC1 Complexes Defines Polycomb-Mediated Gene Repression.

Mol Cell 2019 06 24;74(5):1020-1036.e8. Epub 2019 Apr 24.

Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2019.03.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561741PMC
June 2019

PRC1 preserves epidermal tissue integrity independently of PRC2.

Genes Dev 2019 01 19;33(1-2):55-60. Epub 2018 Dec 19.

Black Family Stem Cell Institute, Department of Cell, Developmental, and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.

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http://genesdev.cshlp.org/lookup/doi/10.1101/gad.319939.118
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http://dx.doi.org/10.1101/gad.319939.118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317312PMC
January 2019

Ubiquitination-Independent Repression of PRC1 Targets during Neuronal Fate Restriction in the Developing Mouse Neocortex.

Dev Cell 2018 12;47(6):758-772.e5

Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo 113-0033, Japan; International Research Center for Neurointelligence (WPI-IRCN), The University of Tokyo, Tokyo 113-0033, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2018.11.018DOI Listing
December 2018

Smchd1 Targeting to the Inactive X Is Dependent on the Xist-HnrnpK-PRC1 Pathway.

Cell Rep 2018 11;25(7):1912-1923.e9

The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Melbourne, VIC 3052, Australia; Department of Medical Biology, University of Melbourne, Melbourne, VIC 3010, Australia; Department of Genetics, University of Melbourne, Melbourne, VIC 3010, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247183163
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http://dx.doi.org/10.1016/j.celrep.2018.10.044DOI Listing
November 2018

Variant PRC1 competes with retinoic acid-related signals to repress in the mouse distal forelimb bud.

Development 2018 10 11;145(19). Epub 2018 Oct 11.

Laboratory for Developmental Genetics, RIKEN Center for Integrative Medical Sciences (RIKEN-IMS), 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama 230-0045, Japan

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http://dx.doi.org/10.1242/dev.166348DOI Listing
October 2018

Identification of the Coiled-Coil Domain as an Essential Methyl-CpG-Binding Domain Protein 3 Element for Preserving Lineage Commitment Potential of Embryonic Stem Cells.

Stem Cells 2018 09 15;36(9):1355-1367. Epub 2018 Jul 15.

Division of Developmental Biology, Research Center for Genomic Medicine, Saitama Medical University, Yamane Hidaka, Saitama, Japan.

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http://dx.doi.org/10.1002/stem.2849DOI Listing
September 2018

Growing oocyte-specific transcription-dependent de novo DNA methylation at the imprinted Zrsr1-DMR.

Epigenetics Chromatin 2018 06 6;11(1):28. Epub 2018 Jun 6.

Division of Molecular Genetics and Epigenetics, Department of Biomolecular Sciences, Faculty of Medicine, Saga University, Saga, 849-8501, Japan.

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http://dx.doi.org/10.1186/s13072-018-0200-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989421PMC
June 2018

PRC1 Fine-tunes Gene Repression and Activation to Safeguard Skin Development and Stem Cell Specification.

Cell Stem Cell 2018 05;22(5):726-739.e7

Black Family Stem Cell Institute, Department of Cell, Developmental, and Regenerative Biology, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2018.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944606PMC
May 2018

Ring1A and Ring1B inhibit expression of Glis2 to maintain murine AML stem cells.

Blood 2018 04 25;131(16):1833-1845. Epub 2018 Jan 25.

Division of Hematological Malignancy, National Cancer Center Research Institute, Tokyo, Japan.

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http://dx.doi.org/10.1182/blood-2017-05-787226DOI Listing
April 2018

Rewriting the past: de novo activity of PRC2 restores global H3K27 methylation patterns.

Nat Struct Mol Biol 2018 03;25(3):197-199

Developmental Genetics Group, Center for Integrative Medical Sciences (IMS), RIKEN, Yokohama, Japan.

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http://dx.doi.org/10.1038/s41594-018-0039-3DOI Listing
March 2018

Hemimethylation: DNA's lasting odd couple.

Science 2018 03;359(6380):1102-1103

Developmental Genetics Group, Center for Integrative Medical Sciences (IMS), RIKEN, 1-7-22 Suehiro, Tsurumi, Yokohama, Kanagawa 230-0045, Japan.

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http://dx.doi.org/10.1126/science.aat0789DOI Listing
March 2018

An endosiRNA-Based Repression Mechanism Counteracts Transposon Activation during Global DNA Demethylation in Embryonic Stem Cells.

Cell Stem Cell 2017 Nov;21(5):694-703.e7

Epigenetics Programme, Babraham Institute, Cambridge CB22 3AT, UK; University of Cambridge, The Old Schools, Trinity Lane, Cambridge CB2 1TN, UK; Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2017.10.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678422PMC
November 2017

Role of UHRF1 in de novo DNA methylation in oocytes and maintenance methylation in preimplantation embryos.

PLoS Genet 2017 Oct 4;13(10):e1007042. Epub 2017 Oct 4.

Division of Epigenomics and Development, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1371/journal.pgen.1007042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643148PMC
October 2017

Samd7 is a cell type-specific PRC1 component essential for establishing retinal rod photoreceptor identity.

Proc Natl Acad Sci U S A 2017 09 12;114(39):E8264-E8273. Epub 2017 Sep 12.

Laboratory for Molecular and Developmental Biology, Institute for Protein Research, Osaka University, Osaka 565-0871, Japan;

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http://dx.doi.org/10.1073/pnas.1707021114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625914PMC
September 2017

No Winter Lasts Forever: Polycomb Complexes Convert Epigenetic Memory of Cold into Flowering.

Dev Cell 2017 09;42(6):563-564

Developmental Genetics Group, Center for Integrative Medical Sciences (IMS), RIKEN, 1-7-22 Suehiuro-cho, Tsurumi-ku, Yokohama-shi, Kanagawa-ken 230-0045, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2017.09.004DOI Listing
September 2017

Requirement of Zinc Transporter SLC39A7/ZIP7 for Dermal Development to Fine-Tune Endoplasmic Reticulum Function by Regulating Protein Disulfide Isomerase.

J Invest Dermatol 2017 08 22;137(8):1682-1691. Epub 2017 May 22.

Division of Pathology, Department of Oral Diagnostic Sciences, School of Dentistry, Showa University, Tokyo, Japan; Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima, Japan; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2017.03.031DOI Listing
August 2017

FANTOM5 CAGE profiles of human and mouse samples.

Authors:
Shuhei Noguchi Takahiro Arakawa Shiro Fukuda Masaaki Furuno Akira Hasegawa Fumi Hori Sachi Ishikawa-Kato Kaoru Kaida Ai Kaiho Mutsumi Kanamori-Katayama Tsugumi Kawashima Miki Kojima Atsutaka Kubosaki Ri-Ichiroh Manabe Mitsuyoshi Murata Sayaka Nagao-Sato Kenichi Nakazato Noriko Ninomiya Hiromi Nishiyori-Sueki Shohei Noma Eri Saijyo Akiko Saka Mizuho Sakai Christophe Simon Naoko Suzuki Michihira Tagami Shoko Watanabe Shigehiro Yoshida Peter Arner Richard A Axton Magda Babina J Kenneth Baillie Timothy C Barnett Anthony G Beckhouse Antje Blumenthal Beatrice Bodega Alessandro Bonetti James Briggs Frank Brombacher Ailsa J Carlisle Hans C Clevers Carrie A Davis Michael Detmar Taeko Dohi Albert S B Edge Matthias Edinger Anna Ehrlund Karl Ekwall Mitsuhiro Endoh Hideki Enomoto Afsaneh Eslami Michela Fagiolini Lynsey Fairbairn Mary C Farach-Carson Geoffrey J Faulkner Carmelo Ferrai Malcolm E Fisher Lesley M Forrester Rie Fujita Jun-Ichi Furusawa Teunis B Geijtenbeek Thomas Gingeras Daniel Goldowitz Sven Guhl Reto Guler Stefano Gustincich Thomas J Ha Masahide Hamaguchi Mitsuko Hara Yuki Hasegawa Meenhard Herlyn Peter Heutink Kelly J Hitchens David A Hume Tomokatsu Ikawa Yuri Ishizu Chieko Kai Hiroshi Kawamoto Yuki I Kawamura Judith S Kempfle Tony J Kenna Juha Kere Levon M Khachigian Toshio Kitamura Sarah Klein S Peter Klinken Alan J Knox Soichi Kojima Haruhiko Koseki Shigeo Koyasu Weonju Lee Andreas Lennartsson Alan Mackay-Sim Niklas Mejhert Yosuke Mizuno Hiromasa Morikawa Mitsuru Morimoto Kazuyo Moro Kelly J Morris Hozumi Motohashi Christine L Mummery Yutaka Nakachi Fumio Nakahara Toshiyuki Nakamura Yukio Nakamura Tadasuke Nozaki Soichi Ogishima Naganari Ohkura Hiroshi Ohno Mitsuhiro Ohshima Mariko Okada-Hatakeyama Yasushi Okazaki Valerio Orlando Dmitry A Ovchinnikov Robert Passier Margaret Patrikakis Ana Pombo Swati Pradhan-Bhatt Xian-Yang Qin Michael Rehli Patrizia Rizzu Sugata Roy Antti Sajantila Shimon Sakaguchi Hiroki Sato Hironori Satoh Suzana Savvi Alka Saxena Christian Schmidl Claudio Schneider Gundula G Schulze-Tanzil Anita Schwegmann Guojun Sheng Jay W Shin Daisuke Sugiyama Takaaki Sugiyama Kim M Summers Naoko Takahashi Jun Takai Hiroshi Tanaka Hideki Tatsukawa Andru Tomoiu Hiroo Toyoda Marc van de Wetering Linda M van den Berg Roberto Verardo Dipti Vijayan Christine A Wells Louise N Winteringham Ernst Wolvetang Yoko Yamaguchi Masayuki Yamamoto Chiyo Yanagi-Mizuochi Misako Yoneda Yohei Yonekura Peter G Zhang Silvia Zucchelli Imad Abugessaisa Erik Arner Jayson Harshbarger Atsushi Kondo Timo Lassmann Marina Lizio Serkan Sahin Thierry Sengstag Jessica Severin Hisashi Shimoji Masanori Suzuki Harukazu Suzuki Jun Kawai Naoto Kondo Masayoshi Itoh Carsten O Daub Takeya Kasukawa Hideya Kawaji Piero Carninci Alistair R R Forrest Yoshihide Hayashizaki

Sci Data 2017 08 29;4:170112. Epub 2017 Aug 29.

RIKEN Omics Science Center, Yokohama, Kanagawa 230-0045, Japan.

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http://dx.doi.org/10.1038/sdata.2017.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574368PMC
August 2017

Polycomb directs timely activation of germline genes in spermatogenesis.

Genes Dev 2017 08 18;31(16):1693-1703. Epub 2017 Sep 18.

Division of Reproductive Sciences, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.

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http://dx.doi.org/10.1101/gad.302000.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647939PMC
August 2017

Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways.

Nat Cell Biol 2017 Jul 12;19(7):763-773. Epub 2017 Jun 12.

Department of Trauma Surgery, Center for Clinical Research, University Hospital Zurich, University of Zurich, Sternwartstrasse 14, CH-8091 Zurich, Switzerland.

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http://dx.doi.org/10.1038/ncb3554DOI Listing
July 2017

Sublethal endoplasmic reticulum stress caused by the mutation of immunoglobulin heavy chain-binding protein induces the synthesis of a mitochondrial protein, pyrroline-5-carboxylate reductase 1.

Cell Stress Chaperones 2017 01 28;22(1):77-85. Epub 2016 Oct 28.

Pain Center, Teikyo University Chiba Medical Center, 3426-3 Anesaki, Ichihara City, Chiba, 299-0111, Japan.

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http://dx.doi.org/10.1007/s12192-016-0741-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225059PMC
January 2017

Regeneration of CD8αβ T Cells from T-cell-Derived iPSC Imparts Potent Tumor Antigen-Specific Cytotoxicity.

Cancer Res 2016 12 21;76(23):6839-6850. Epub 2016 Nov 21.

Laboratory of Immunology, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-1149DOI Listing
December 2016

NOV/CCN3: A New Adipocytokine Involved in Obesity-Associated Insulin Resistance.

Diabetes 2016 09 9;65(9):2502-15. Epub 2016 Jun 9.

Sorbonne Universities, Pierre and Marie Curie University Paris 06, INSERM, Saint-Antoine Research Center, Saint-Antoine Hospital, Paris, France Hospitalo-Universitary Institute, ICAN, Paris, France Department of Endocrinology, Paris, Assistance Publique-Hôpitaux de Paris, Saint-Antoine Hospital, Paris, France

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http://dx.doi.org/10.2337/db15-0617DOI Listing
September 2016

ThPOK represses CXXC5, which induces methylation of histone H3 lysine 9 in Cd40lg promoter by association with SUV39H1: implications in repression of CD40L expression in CD8+ cytotoxic T cells.

J Leukoc Biol 2016 08 19;100(2):327-38. Epub 2016 Feb 19.

Department of Mechanism of Aging, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan;

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http://dx.doi.org/10.1189/jlb.1A0915-396RRDOI Listing
August 2016

Activation of Endogenous Retroviruses in Dnmt1(-/-) ESCs Involves Disruption of SETDB1-Mediated Repression by NP95 Binding to Hemimethylated DNA.

Cell Stem Cell 2016 07 14;19(1):81-94. Epub 2016 Apr 14.

Laboratory for Developmental Genetics, RIKEN Center for Integrative Medical Sciences (IMS), 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2016.03.013DOI Listing
July 2016

Immunoresponsive Gene 1 and Itaconate Inhibit Succinate Dehydrogenase to Modulate Intracellular Succinate Levels.

J Biol Chem 2016 Jul 9;291(27):14274-84. Epub 2016 May 9.

From the Departments of Bioengineering and Institute of Engineering in Medicine, University of California, San Diego, La Jolla, California 92093,

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http://www.jbc.org/lookup/doi/10.1074/jbc.M115.685792
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http://dx.doi.org/10.1074/jbc.M115.685792DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933182PMC
July 2016

De novo DNA methylation drives 5hmC accumulation in mouse zygotes.

Nat Cell Biol 2016 Feb 11;18(2):225-233. Epub 2016 Jan 11.

Medical Research Council Clinical Sciences Centre, Imperial College London, London W12 0NN, United Kingdom.

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http://dx.doi.org/10.1038/ncb3296DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765106PMC
February 2016

Late-onset of spinal neurodegeneration in knock-in mice expressing a mutant BiP.

PLoS One 2014 18;9(11):e112837. Epub 2014 Nov 18.

Department of Anesthesiology, Chiba University Graduate School of Medicine, Chiba City, Chiba, Japan; Department of Anesthesiology, Tokyo Women's Medical University, Yachiyo Medical, Center, Yachiyo, Chiba, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0112837PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236098PMC
January 2016

Polycomb Complex PRC1 Preserves Intestinal Stem Cell Identity by Sustaining Wnt/β-Catenin Transcriptional Activity.

Cell Stem Cell 2016 Jan 29;18(1):91-103. Epub 2015 Oct 29.

Department of Experimental Oncology, European Institute of Oncology, Via Adamello 16, 20139 Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2015.09.019DOI Listing
January 2016

RING1 proteins contribute to early proximal-distal specification of the forelimb bud by restricting Meis2 expression.

Development 2016 Jan 16;143(2):276-85. Epub 2015 Dec 16.

Laboratory for Developmental Genetics, RIKEN Center for Integrative Medical Sciences (IMS), 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama 230-0045, Japan CREST, Japan Science and Technology Agency, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama 230-0045, Japan

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http://dev.biologists.org/content/develop/early/2015/12/16/d
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http://dev.biologists.org/cgi/doi/10.1242/dev.127506
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http://dx.doi.org/10.1242/dev.127506DOI Listing
January 2016

Polycomb in Transcriptional Phase Transition of Developmental Genes.

Trends Biochem Sci 2016 Jan 8;41(1):9-19. Epub 2015 Dec 8.

RIKEN-IMS, 1-7-22 Suehirocho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan; CREST, 1-7-22 Suehirocho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.tibs.2015.11.005DOI Listing
January 2016

Role of Polycomb RYBP in Maintaining the B-1-to-B-2 B-Cell Lineage Switch in Adult Hematopoiesis.

Mol Cell Biol 2015 Dec 28;36(6):900-12. Epub 2015 Dec 28.

Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, Madrid, Spain

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http://dx.doi.org/10.1128/MCB.00869-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810469PMC
December 2015

Roles of histone H3K27 trimethylase Ezh2 in retinal proliferation and differentiation.

Dev Neurobiol 2015 Sep 16;75(9):947-60. Epub 2015 Jan 16.

Division of Molecular and Developmental Biology, Institute of Medical Science, University of Tokyo, Tokyo.

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http://dx.doi.org/10.1002/dneu.22261DOI Listing
September 2015

CNOT3 contributes to early B cell development by controlling Igh rearrangement and p53 mRNA stability.

J Exp Med 2015 Aug 3;212(9):1465-79. Epub 2015 Aug 3.

Laboratory of Lymphocyte Differentiation, WPI Immunology Frontier Research Center, Osaka University, Suita, Osaka 565-0871, Japan Laboratory for Integrative Genomics, Laboratory for Developmental Genetics, Laboratory for Immune Regeneration, and Laboratory for Lymphocyte Differentiation, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa 230-0045, Japan

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http://dx.doi.org/10.1084/jem.20150384DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548056PMC
August 2015

Application of iPS technology for NKT cell-mediated tumor immunotherapy.

Nihon Rinsho 2015 Jun;73 Suppl 5:257-60

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June 2015

KDEL receptor 1 regulates T-cell homeostasis via PP1 that is a key phosphatase for ISR.

Nat Commun 2015 Jun 17;6:7474. Epub 2015 Jun 17.

1] Division of Molecular Neuroimmunology, Institute for Genetic Medicine and Graduate School of Medicine, Hokkaido University, Kita-15, Nishi-7, Kita-ku, Sapporo 060-0815, Japan [2] Laboratory of Developmental Immunology, Graduate School of Frontier Biosciences, Graduate School of Medicine, and WPI Immunology Frontier Research Center, Osaka University, 2-2, Yamada-oka, Suita 565-0871, Japan.

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http://dx.doi.org/10.1038/ncomms8474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557295PMC
June 2015

Polycomb group protein Ezh2 regulates hepatic progenitor cell proliferation and differentiation in murine embryonic liver.

PLoS One 2014 25;9(8):e104776. Epub 2014 Aug 25.

Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Kanazawa-ku, Yokohama, Kanagawa, Japan; Project Leader of Advanced Medical Research Center, Yokohama City University, Kanazawa-ku, Yokohama, Kanagawa, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0104776PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143191PMC
May 2015

Generating a transgenic mouse line stably expressing human MHC surface antigen from a HAC carrying multiple genomic BACs.

Chromosoma 2015 Mar 12;124(1):107-18. Epub 2014 Oct 12.

Laboratory of Cell Engineering, Department of Frontier Research, Kazusa DNA Research Institute, 2-6-7 Kazusa-Kamatari, Kisarazu, Chiba, 292-0818, Japan.

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http://dx.doi.org/10.1007/s00412-014-0488-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339693PMC
March 2015

Physical interaction between MPP8 and PRC1 complex and its implication for regulation of spermatogenesis.

Biochem Biophys Res Commun 2015 Mar 7;458(3):470-475. Epub 2015 Feb 7.

Department of Cell Biology, Graduate School of Medical Sciences, Nagoya City University, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, 467-8601, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2015.01.122DOI Listing
March 2015

Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells.

Authors:
Erik Arner Carsten O Daub Kristoffer Vitting-Seerup Robin Andersson Berit Lilje Finn Drabløs Andreas Lennartsson Michelle Rönnerblad Olga Hrydziuszko Morana Vitezic Tom C Freeman Ahmad M N Alhendi Peter Arner Richard Axton J Kenneth Baillie Anthony Beckhouse Beatrice Bodega James Briggs Frank Brombacher Margaret Davis Michael Detmar Anna Ehrlund Mitsuhiro Endoh Afsaneh Eslami Michela Fagiolini Lynsey Fairbairn Geoffrey J Faulkner Carmelo Ferrai Malcolm E Fisher Lesley Forrester Daniel Goldowitz Reto Guler Thomas Ha Mitsuko Hara Meenhard Herlyn Tomokatsu Ikawa Chieko Kai Hiroshi Kawamoto Levon M Khachigian S Peter Klinken Soichi Kojima Haruhiko Koseki Sarah Klein Niklas Mejhert Ken Miyaguchi Yosuke Mizuno Mitsuru Morimoto Kelly J Morris Christine Mummery Yutaka Nakachi Soichi Ogishima Mariko Okada-Hatakeyama Yasushi Okazaki Valerio Orlando Dmitry Ovchinnikov Robert Passier Margaret Patrikakis Ana Pombo Xian-Yang Qin Sugata Roy Hiroki Sato Suzana Savvi Alka Saxena Anita Schwegmann Daisuke Sugiyama Rolf Swoboda Hiroshi Tanaka Andru Tomoiu Louise N Winteringham Ernst Wolvetang Chiyo Yanagi-Mizuochi Misako Yoneda Susan Zabierowski Peter Zhang Imad Abugessaisa Nicolas Bertin Alexander D Diehl Shiro Fukuda Masaaki Furuno Jayson Harshbarger Akira Hasegawa Fumi Hori Sachi Ishikawa-Kato Yuri Ishizu Masayoshi Itoh Tsugumi Kawashima Miki Kojima Naoto Kondo Marina Lizio Terrence F Meehan Christopher J Mungall Mitsuyoshi Murata Hiromi Nishiyori-Sueki Serkan Sahin Sayaka Nagao-Sato Jessica Severin Michiel J L de Hoon Jun Kawai Takeya Kasukawa Timo Lassmann Harukazu Suzuki Hideya Kawaji Kim M Summers Christine Wells David A Hume Alistair R R Forrest Albin Sandelin Piero Carninci Yoshihide Hayashizaki

Science 2015 Feb 12;347(6225):1010-4. Epub 2015 Feb 12.

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http://dx.doi.org/10.1126/science.1259418DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681433PMC
February 2015

Clustering of CARMA1 through SH3-GUK domain interactions is required for its activation of NF-κB signalling.

Nat Commun 2015 Jan 20;6:5555. Epub 2015 Jan 20.

Laboratory for Cell Signaling, RIKEN Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan.

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http://dx.doi.org/10.1038/ncomms6555DOI Listing
January 2015

Histone acetylation mediated by Brd1 is crucial for Cd8 gene activation during early thymocyte development.

Nat Commun 2014 Dec 18;5:5872. Epub 2014 Dec 18.

1] Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan [2] JST, CREST, 7 Gobancho, Chiyoda-ku, Tokyo 102-0076, Japan.

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http://dx.doi.org/10.1038/ncomms6872DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490789PMC
December 2014

The polycomb component Ring1B regulates the timed termination of subcerebral projection neuron production during mouse neocortical development.

Development 2014 Nov 24;141(22):4343-53. Epub 2014 Oct 24.

Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan Institute of Molecular and Cellular Biosciences, The University of Tokyo, Tokyo, Japan

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http://dx.doi.org/10.1242/dev.112276DOI Listing
November 2014

Generation of induced pluripotent stem cell-derived mice by reprogramming of a mature NKT cell.

Int Immunol 2014 Oct 22;26(10):551-61. Epub 2014 May 22.

Laboratory for Immune Regulation, RCAI, RIKEN Center for Integrative Medical Sciences (IMS-RCAI), 230-0045 Kanagawa, Japan

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http://dx.doi.org/10.1093/intimm/dxu057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169672PMC
October 2014

Zinc transporter SLC39A10/ZIP10 facilitates antiapoptotic signaling during early B-cell development.

Proc Natl Acad Sci U S A 2014 Aug 29;111(32):11780-5. Epub 2014 Jul 29.

Laboratory for Homeostatic Network,Division of Pathology, Department of Oral Diagnostic Sciences, School of Dentistry, Showa University, Hatanodai, Shinagawa, Tokyo 142-8555, Japan;

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http://www.pnas.org/cgi/doi/10.1073/pnas.1323549111
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http://dx.doi.org/10.1073/pnas.1323549111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136617PMC
August 2014

Zinc transporter SLC39A10/ZIP10 controls humoral immunity by modulating B-cell receptor signal strength.

Proc Natl Acad Sci U S A 2014 Aug 29;111(32):11786-91. Epub 2014 Jul 29.

Laboratory for Homeostatic Network,Division of Pathology, Department of Oral Diagnostic Sciences, School of Dentistry, Showa University, Tokyo 142-8555, Japan;

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http://dx.doi.org/10.1073/pnas.1323557111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136588PMC
August 2014

Guanine- 5-carboxylcytosine base pairs mimic mismatches during DNA replication.

Sci Rep 2014 Jun 9;4:5220. Epub 2014 Jun 9.

Graduate School of Engineering Science, Osaka University Graduate School of Engineering Science, 1-3 Machikaneyama, Toyonaka, Osaka 560-8531 Japan.

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http://dx.doi.org/10.1038/srep05220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048885PMC
June 2014

Ezh2 loss promotes development of myelodysplastic syndrome but attenuates its predisposition to leukaemic transformation.

Nat Commun 2014 Jun 23;5:4177. Epub 2014 Jun 23.

1] Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan [2] JST, CREST, 7 Gobancho, Chiyoda-ku, Tokyo 102-0076, Japan.

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http://dx.doi.org/10.1038/ncomms5177DOI Listing
June 2014