Hartwig Huland

Reduced anoctamin 7 (ANO7) expression is a strong and independent predictor of poor prognosis in prostate cancer.

Cancer Biol Med 2021 Feb;18(1):245-255

Department of Urology, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.

February 2021

Effect of prostatic apex shape (Lee types) and urethral sphincter length in preoperative MRI on very early continence rates after radical prostatectomy.

Authors:

Mike Wenzel Felix Preisser Matthias Mueller Lena H Theissen Maria N Welte Benedikt Hoeh Clara Humke Simon Bernatz Boris Bodelle Christoph Würnschimmel Derya Tilki Hartwig Huland Markus Graefen Frederik C Roos Andreas Becker Pierre I Karakiewicz Felix K H Chun Luis A Kluth Philipp Mandel

Int Urol Nephrol 2021 Feb 19. Epub 2021 Feb 19.

Department of Urology, University Hospital Frankfurt, Goethe University, Frankfurt am Main, Germany.

View Article and Find Full Text PDF

February 2021

Opposing prognostic relevance of junction plakoglobin in distinct prostate cancer patient subsets.

Authors:

Tanja Spethmann Lukas Clemens Böckelmann Vera Labitzky Ann-Kristin Ahlers Jennifer Schröder-Schwarz Sarah Bonk Ronald Simon Guido Sauter Hartwig Huland Robert Kypta Udo Schumacher Tobias Lange

Mol Oncol 2021 Feb 3. Epub 2021 Feb 3.

Institute of Anatomy and Experimental Morphology, Center for Experimental Medicine, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, Germany.

View Article and Find Full Text PDF

February 2021

Overexpression of the TRIM24 E3 Ubiquitin Ligase is Linked to Genetic Instability and Predicts Unfavorable Prognosis in Prostate Cancer.

Appl Immunohistochem Mol Morphol 2021 Jan 22. Epub 2021 Jan 22.

Institute of Pathology General, Visceral and Thoracic Surgery Department and Clinic Martini-Clinic, Prostate Cancer Center, University Medical Center Hamburg, Eppendorf Department of Urology, Charité-Universitätsmedizin Berlin, Germany.

View Article and Find Full Text PDF

January 2021

CHD1 loss negatively influences metastasis-free survival in R0-resected prostate cancer patients and promotes spontaneous metastasis in vivo.

Cancer Gene Ther 2021 Jan 7. Epub 2021 Jan 7.

Institute of Anatomy and Experimental Morphology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.

View Article and Find Full Text PDF

January 2021

Epithelial splicing regulatory protein 1 and 2 (ESRP1 and ESRP2) upregulation predicts poor prognosis in prostate cancer.

BMC Cancer 2020 Dec 18;20(1):1220. Epub 2020 Dec 18.

Institute of Pathology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany.

View Article and Find Full Text PDF

December 2020

Increased Cytoplasmic CD138 Expression Is Associated with Aggressive Characteristics in Prostate Cancer and Is an Independent Predictor for Biochemical Recurrence.

Biomed Res Int 2020 28;2020:5845374. Epub 2020 Oct 28.

General, Visceral and Thoracic Surgery Department and Clinic, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.

View Article and Find Full Text PDF

October 2020

Re: Paolo Afonso de Carvalho, Joāo A.B.A. Barbosa, Giuliano B. Guglielmetti, et al. Retrograde Release of the Neurovascular Bundle with Preservation of Dorsal Venous Complex During Robot-assisted Radical Prostatectomy: Optimizing Functional Outcomes. Eur Urol 2020;77:628-35: Incredible Results for Robot-assisted Nerve-sparing Radical Prostatectomy in Prostate Cancer Patients.

Authors:

Francesco Montorsi Giorgio Gandaglia Christoph Würnschimmel Markus Graefen Alberto Briganti Hartwig Huland

Eur Urol 2021 Feb 14;79(2):e44-e46. Epub 2020 Oct 14.

Martini-Klinik Prostate Cancer Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

View Article and Find Full Text PDF

February 2021

Chromosome 5 harbors two independent deletion hotspots at 5q13 and 5q21 that characterize biologically different subsets of aggressive prostate cancer.

Authors:

Katharina Möller Martina Kluth Malik Ahmed Lia Burkhardt Christina Möller-Koop Franziska Büscheck Sören Weidemann Maria-Christina Tsourlakis Sarah Minner Hans Heinzer Hartwig Huland Markus Graefen Guido Sauter Thorsten Schlomm David Dum Ronald Simon

Int J Cancer 2021 Feb 24;148(3):748-758. Epub 2020 Oct 24.

Institute of Pathology, University Medical Center, Hamburg-Eppendorf, Germany.

View Article and Find Full Text PDF

February 2021

Second-Generation Antiandrogen Therapy Radiosensitizes Prostate Cancer Regardless of Castration State through Inhibition of DNA Double Strand Break Repair.

Authors:

Mohamed E Elsesy Su Jung Oh-Hohenhorst Anastassia Löser Christoph Oing Sally Mutiara Sabrina Köcher Stefanie Meien Alexandra Zielinski Susanne Burdak-Rothkamm Derya Tilki Hartwig Huland Rudolf Schwarz Cordula Petersen Carsten Bokemeyer Kai Rothkamm Wael Y Mansour

Cancers (Basel) 2020 Aug 31;12(9). Epub 2020 Aug 31.

Department of Radiotherapy and Radiooncology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.

View Article and Find Full Text PDF

August 2020

Association of neurovascular bundle preservation with oncological outcomes in patients with high-risk prostate cancer.

Authors:

Felix Preisser Giorgio Gandaglia Farid Arad Pierre I Karakiewicz Marco Bandini Raisa S Pompe Francesco Montorsi Markus Graefen Hartwig Huland Alberto Briganti Derya Tilki

Prostate Cancer Prostatic Dis 2020 Aug 19. Epub 2020 Aug 19.

Martini-Klinik Prostate Cancer Center, University Hospital Hamburg Eppendorf, Hamburg, Germany.

View Article and Find Full Text PDF

August 2020

Xenograft-derived mRNA/miR and protein interaction networks of systemic dissemination in human prostate cancer.

Eur J Cancer 2020 09 1;137:93-107. Epub 2020 Aug 1.

Institute of Anatomy and Experimental Morphology, University Medical Center, Hamburg-Eppendorf, Martinistrasse 52, Hamburg, Germany.

View Article and Find Full Text PDF

September 2020

Secreted Frizzled-Related Protein 4 (SFRP4) Is an Independent Prognostic Marker in Prostate Cancers Lacking TMPRSS2: ERG Fusions.

Pathol Oncol Res 2020 Oct 16;26(4):2709-2722. Epub 2020 Jul 16.

General, Visceral and Thoracic Surgery Department and Clinic, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

View Article and Find Full Text PDF

October 2020

Reduced KLK2 expression is a strong and independent predictor of poor prognosis in ERG-negative prostate cancer.

Prostate 2020 09 6;80(13):1097-1107. Epub 2020 Jul 6.

Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

View Article and Find Full Text PDF

September 2020

Up regulation of the Hippo signalling effector YAP1 is linked to early biochemical recurrence in prostate cancers.

Sci Rep 2020 06 2;10(1):8916. Epub 2020 Jun 2.

Institute of Pathology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.

View Article and Find Full Text PDF

June 2020

A pre-specified model based on four kallikrein markers in blood improves predictions of adverse pathology and biochemical recurrence after radical prostatectomy.

Authors:

Alexander Haese Amy L Tin Sigrid V Carlsson Daniel D Sjoberg Dirk Pehrke Thomas Steuber Hartwig Huland Markus Graefen Peter T Scardino Thorsten Schlomm Andrew J Vickers Hans Lilja Guido Sauter

Br J Cancer 2020 08 29;123(4):604-609. Epub 2020 May 29.

Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

View Article and Find Full Text PDF

August 2020

Martini-Klinik experience of prostate cancer surgery during the early phase of the COVID-19 pandemic.

Authors:

Christoph Würnschimmel Tobias Maurer Sophie Knipper Franziska von Breunig Christian Zoellner Imke Thederan Hartwig Huland Markus Graefen Uwe Michl

BJU Int 2020 08 4;126(2):252-255. Epub 2020 Aug 4.

Martini-Klinik Prostate Cancer Centre Hamburg, Hamburg, Germany.

View Article and Find Full Text PDF

August 2020

Upregulation of the heterogeneous nuclear ribonucleoprotein hnRNPA1 is an independent predictor of early biochemical recurrence in TMPRSS2:ERG fusion-negative prostate cancers.

Virchows Arch 2020 Nov 16;477(5):625-636. Epub 2020 May 16.

Institute of Pathology, Klinikum Fürth, Fürth, Germany.

View Article and Find Full Text PDF

November 2020

Upregulation of Phosphatase 1 Nuclear-Targeting Subunit (PNUTS) Is an Independent Predictor of Poor Prognosis in Prostate Cancer.

Dis Markers 2020 25;2020:7050146. Epub 2020 Apr 25.

General, Visceral and Thoracic Surgery Department and Clinic, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.

View Article and Find Full Text PDF

February 2021

High CHK2 protein expression is a strong and independent prognostic feature in ERG negative prostate cancer.

Pathology 2020 Jun 18;52(4):421-430. Epub 2020 Apr 18.

Institute of Pathology, University Medical Center Hamburg-Eppendorf, Germany.

View Article and Find Full Text PDF

June 2020

Upregulation of PTTG1 is associated with poor prognosis in prostate cancer.

Pathol Int 2020 Jul 20;70(7):441-451. Epub 2020 Apr 20.

Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

View Article and Find Full Text PDF

July 2020

Validation of the updated eighth edition of AJCC for prostate cancer: Removal of pT2 substages - Does extent of tumor involvement matter?

Authors:

Raisa S Pompe Tim Neumann Lennart Kühnke Felix Preisser Philipp Gild Pierre Tennstedt Georg Salomon Hartwig Huland Derya Tilki

Urol Oncol 2020 07 31;38(7):637.e1-637.e7. Epub 2020 Mar 31.

Martini-Klinik Prostate Cancer Center, University Hospital Hamburg-Eppendorf, Hamburg, Germany; Department of Urology, University Hospital Hamburg-Eppendorf, Hamburg, Germany. Electronic address:

View Article and Find Full Text PDF

July 2020

Association of Age With Risk of Adverse Pathological Findings at Radical Prostatectomy in Men With Gleason Score 6 Prostate Cancer.

Authors:

Daniel W Kim Ming-Hui Chen Hartwig Huland Markus Graefen Derya Tilki Anthony V D'Amico

JAMA Netw Open 2020 04 1;3(4):e202041. Epub 2020 Apr 1.

Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston, Massachusetts.

View Article and Find Full Text PDF

April 2020

Loss of the adhesion molecule CEACAM1 is associated with early biochemical recurrence in TMPRSS2:ERG fusion-positive prostate cancers.

Int J Cancer 2020 07 18;147(2):575-583. Epub 2020 Mar 18.

General, Visceral and Thoracic Surgery Department and Clinic, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

View Article and Find Full Text PDF

July 2020

Upregulation of the transcription factor TFAP2D is associated with aggressive tumor phenotype in prostate cancer lacking the TMPRSS2:ERG fusion.

Mol Med 2020 03 6;26(1):24. Epub 2020 Mar 6.

General, Visceral and Thoracic Surgery Department and Clinic, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

View Article and Find Full Text PDF

March 2020

Subcellular Compartmentalization of Survivin is Associated with Biological Aggressiveness and Prognosis in Prostate Cancer.

Authors:

Jan K Hennigs Sarah Minner Pierre Tennstedt Rolf Löser Hartwig Huland Hans Klose Markus Graefen Thorsten Schlomm Guido Sauter Carsten Bokemeyer Friedemann Honecker

Sci Rep 2020 02 24;10(1):3250. Epub 2020 Feb 24.

Department of Internal Medicine II - Oncology, Hematology, Bone Marrow Transplantation and Pneumology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

View Article and Find Full Text PDF

February 2020

The Significance of Primary Biopsy Gleason 5 in Patients with Grade Group 5 Prostate Cancer.

Authors:

Derya Tilki Christoph Würnschimmel Felix Preisser Markus Graefen Hartwig Huland Philipp Mandel Pierre Tennstedt

Eur Urol Focus 2020 03 6;6(2):255-258. Epub 2020 Feb 6.

Martini-Klinik Prostate Cancer Center, University Hospital Hamburg-Eppendorf, Hamburg, Germany.

View Article and Find Full Text PDF

March 2020

The impact of very high initial PSA on oncological outcomes after radical prostatectomy for clinically localized prostate cancer.

Authors:

Derya Tilki Philipp Mandel Pierre I Karakiewicz Alexander Heinze Hartwig Huland Markus Graefen Sophie Knipper

Urol Oncol 2020 05 27;38(5):379-385. Epub 2020 Jan 27.

Martini-Klinik Prostate Cancer Center, University Hospital Hamburg-Eppendorf, Hamburg, Germany; Cancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montreal Health Center, Montreal, Quebec, Canada. Electronic address:

View Article and Find Full Text PDF

May 2020

Definition of high-risk prostate cancer impacts oncological outcomes after radical prostatectomy.

Authors:

Sophie Knipper Pierre I Karakiewicz Alexander Heinze Felix Preisser Thomas Steuber Hartwig Huland Markus Graefen Derya Tilki

Urol Oncol 2020 04 9;38(4):184-190. Epub 2020 Jan 9.

Martini-Klinik Prostate Cancer Center, University Hospital Hamburg-Eppendorf, Hamburg, Germany; Department of Urology, University Hospital Hamburg-Eppendorf, Hamburg, Germany.

View Article and Find Full Text PDF

April 2020

Nuclear up regulation of the BRCA1-associated ubiquitinase BAP1 is associated with tumor aggressiveness in prostate cancers lacking the TMPRSS2:ERG fusion.

Oncotarget 2019 Dec 24;10(67):7096-7111. Epub 2019 Dec 24.

General, Visceral and Thoracic Surgery Department and Clinic, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.

View Article and Find Full Text PDF

December 2019

Publications by authors named "Hartwig Huland"

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors: