Hartmut Goldschmidt

Hartmut Goldschmidt

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Hartmut Goldschmidt

Hartmut Goldschmidt

Publications by authors named "Hartmut Goldschmidt"

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Do we need cytogenetics in the follow-up of multiple myeloma?

Br J Haematol 2019 Feb 1. Epub 2019 Feb 1.

Section Multiple Myeloma, Department Haematology, Oncology and Rheumatology, University Hospital Heidelberg and National Center for Tumor Diseases Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1111/bjh.15781DOI Listing
February 2019

Navigating the treatment landscape in multiple myeloma: which combinations to use and when?

Ann Hematol 2019 Jan 23;98(1):1-18. Epub 2018 Nov 23.

INSERM, UMR_S 938, Proliferation and Differentiation of Stem Cells, Paris, 75012, France.

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http://dx.doi.org/10.1007/s00277-018-3546-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334731PMC
January 2019

Cell-based immunotherapy approaches for multiple myeloma.

Br J Cancer 2019 Jan 6;120(1):38-44. Epub 2018 Dec 6.

Department of Hematology, Oncology and Rheumatology, Heidelberg University, Heidelberg, Germany.

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http://dx.doi.org/10.1038/s41416-018-0346-9DOI Listing
January 2019

Author Correction: Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma.

Nat Commun 2019 01 10;10(1):213. Epub 2019 Jan 10.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, SW7 3RP, UK.

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http://www.nature.com/articles/s41467-018-08107-8
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http://dx.doi.org/10.1038/s41467-018-08107-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328616PMC
January 2019

Cytogenetic abnormalities in monoclonal gammopathy of undetermined significance.

Leukemia 2018 Dec 6;32(12):2717-2719. Epub 2018 Jul 6.

Department of Hematology, Oncology and Rheumatology, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1038/s41375-018-0202-1DOI Listing
December 2018

Oncogene-induced senescence: a potential breakpoint mechanism against malignant transformation in plasma cell disorders.

Leuk Lymphoma 2018 Nov 4;59(11):2660-2669. Epub 2018 Apr 4.

a Department of Internal Medicine V , University Hospital Heidelberg , Heidelberg , Germany.

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http://dx.doi.org/10.1080/10428194.2018.1443450DOI Listing
November 2018

Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma.

Nat Commun 2018 09 13;9(1):3707. Epub 2018 Sep 13.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, SW7 3RP, UK.

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http://www.nature.com/articles/s41467-018-04989-w
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http://dx.doi.org/10.1038/s41467-018-04989-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137048PMC
September 2018

Chemotherapy-induced peripheral neuropathy: evidence from genome-wide association studies and replication within multiple myeloma patients.

BMC Cancer 2018 Aug 15;18(1):820. Epub 2018 Aug 15.

Division of Molecular Genetic Epidemiology, German cancer research center (DKFZ), Im Neuenheimer Feld 580, DE-69120, Heidelberg, Germany.

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http://dx.doi.org/10.1186/s12885-018-4728-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094450PMC
August 2018

Going the distance: Are we losing patients along the multiple myeloma treatment pathway?

Crit Rev Oncol Hematol 2018 Jun 29;126:19-23. Epub 2018 Mar 29.

Department of Internal Medicine V, University Hospital Heidelberg, and National Center for Tumor Diseases (NCT), Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.critrevonc.2018.03.021DOI Listing
June 2018

Cytogenetic aberrations in multiple myeloma are associated with shifts in serum immunoglobulin isotypes distribution and levels.

Haematologica 2018 Apr 1;103(4):e162-e164. Epub 2018 Feb 1.

Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.3324/haematol.2017.184226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865437PMC
April 2018

Improvement in Overall Survival With Carfilzomib, Lenalidomide, and Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma.

J Clin Oncol 2018 Mar 17;36(8):728-734. Epub 2018 Jan 17.

David S. Siegel, John Theurer Cancer Center, Hackensack University Medical Center, Hackensack, NJ; Meletios A. Dimopoulos, National and Kapodistrian University of Athens, Athens, Greece; Heinz Ludwig, Wilhelminen Cancer Research Institute, Wilhelminenspital, Vienna, Austria; Thierry Facon, Hôpital Claude Huriez, Centre Hospitalier Régional Universitaire de Lille, Lille, France; Hartmut Goldschmidt, Heidelberg Medical University and National Center of Tumor Diseases, Heidelberg, Germany; Andrzej Jakubowiak, University of Chicago Medicine, Chicago, IL; Jesus San-Miguel, Clinica Universidad de Navarra-Centro de Investigación Médica Aplicada, Instituto de Investigación Sanitaria de Navarra, Centro de Investigación Biomédica en Red de Cáncer, Pamplona, Spain; Mihaela Obreja and Julie Blaedel, Amgen, Thousand Oaks, CA; and A. Keith Stewart, Mayo Clinic, Scottsdale, AZ.

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http://dx.doi.org/10.1200/JCO.2017.76.5032DOI Listing
March 2018

Bortezomib-induced peripheral neuropathy: A genome-wide association study on multiple myeloma patients.

Hematol Oncol 2018 Feb 20;36(1):232-237. Epub 2017 Mar 20.

Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1002/hon.2391DOI Listing
February 2018

Efficacy and tolerability of the histone deacetylase inhibitor panobinostat in clinical practice.

Hematol Oncol 2018 Feb 7;36(1):210-216. Epub 2017 Jul 7.

Department of Hematology, Oncology and Rheumatology, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1002/hon.2462DOI Listing
February 2018

Therapeutic monoclonal antibodies in combination with pomalidomide can overcome refractoriness to both agents in multiple myeloma: A case-based approach.

Hematol Oncol 2018 Feb 25;36(1):258-261. Epub 2017 Aug 25.

Hematology, Oncology and Rheumatology, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1002/hon.2473DOI Listing
February 2018

Upregulation of FOXM1 in a subset of relapsed myeloma results in poor outcome.

Blood Cancer J 2018 02 15;8(2):22. Epub 2018 Feb 15.

Department of Pathology, The University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, 52242, Iowa, USA.

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http://dx.doi.org/10.1038/s41408-018-0060-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814454PMC
February 2018

Platelet Count before Peripheral Blood Stem Cell Mobilization Is Associated with the Need for Plerixafor But Not with the Collection Result.

Transfus Med Hemother 2018 Jan 4;45(1):24-31. Epub 2017 Oct 4.

Institute of Transfusion Medicine and Immunology, Medical Faculty Mannheim, Heidelberg University, German Red Cross Blood Service Baden-Württemberg - Hesse, Mannheim, Germany.

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http://dx.doi.org/10.1159/000478911DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836245PMC
January 2018

Meeting report of the 6th Heidelberg Myeloma Workshop: current status and developments in diagnosis and therapy of multiple myeloma.

J Cancer Res Clin Oncol 2017 Dec 26;143(12):2521-2526. Epub 2017 Jun 26.

Hematology, Oncology and Rheumatology, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00432-017-2463-xDOI Listing
December 2017

Comparison of Different Stem Cell Mobilization Regimens in AL Amyloidosis Patients.

Biol Blood Marrow Transplant 2017 Nov 25;23(11):1870-1878. Epub 2017 Jul 25.

Department of Hematology, Oncology and Rheumatology, Heidelberg University, Germany; Amyloidosis Center, Heidelberg University, Germany.

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http://dx.doi.org/10.1016/j.bbmt.2017.07.015DOI Listing
November 2017

Quantitative analysis of F-NaF dynamic PET/CT cannot differentiate malignant from benign lesions in multiple myeloma.

Am J Nucl Med Mol Imaging 2017 1;7(4):148-156. Epub 2017 Sep 1.

Clinical Cooperation Unit Nuclear Medicine, German Cancer Research Center (DKFZ)Heidelberg, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596317PMC
September 2017

Diagnosis and treatment of multiple myeloma in Germany: analysis of a nationwide multi-institutional survey.

Ann Hematol 2017 Jun 13;96(6):987-993. Epub 2017 Apr 13.

Medizinische Klinik V, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00277-017-2991-0DOI Listing
June 2017

[Current Aspects in Diagnosis and Therapy of Plasma Cell Myeloma].

Dtsch Med Wochenschr 2017 Jun 31;142(11):800-804. Epub 2017 May 31.

Medizinische Klinik V, Universitätsklinikum Heidelberg.

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http://dx.doi.org/10.1055/s-0043-100295DOI Listing
June 2017

Storage Duration of Autologous Stem Cell Preparations Has No Impact on Hematopoietic Recovery after Transplantation.

Biol Blood Marrow Transplant 2017 Apr 21;23(4):684-690. Epub 2016 Dec 21.

Department of Medicine V, Heidelberg University, Heidelberg, Germany; Institute of Transfusion Medicine and Immunology, German Red Cross Blood Service Baden-Württemberg-Hessen, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2016.12.631DOI Listing
April 2017

Genetic Susceptibility to Bortezomib-Induced Peripheral Neuroropathy: Replication of the Reported Candidate Susceptibility Loci.

Neurochem Res 2017 Mar 16;42(3):925-931. Epub 2016 Jul 16.

Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1007/s11064-016-2007-9DOI Listing
March 2017

Baseline characteristics, chromosomal alterations, and treatment affecting prognosis of deletion 17p in newly diagnosed myeloma.

Am J Hematol 2016 Nov 3;91(11):E473-E477. Epub 2016 Sep 3.

Medizinische Klinik V, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1002/ajh.24533DOI Listing
November 2016

Galectin-8 enhances adhesion of multiple myeloma cells to vascular endothelium and is an adverse prognostic factor.

Glycobiology 2016 10 10;26(10):1048-1058. Epub 2016 Jun 10.

Clinical Cooperation Unit Applied Tumor Immunity, Deutsches Krebsforschungszentrum, 69120 Heidelberg, Germany

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http://dx.doi.org/10.1093/glycob/cww066DOI Listing
October 2016

Daratumumab, Lenalidomide, and Dexamethasone for Multiple Myeloma.

N Engl J Med 2016 10;375(14):1319-1331

From the National and Kapodistrian University of Athens, Athens (M.A.D.); Institut Català d'Oncologia, Institut Josep Carreras, Hospital Germans Trias I Pujol, Barcelona (A.O.), and Clínica Universidad de Navarra-Centro de Investigación Médica Aplicada, Instituto de Investigación Sanitaria de Navarra, Pamplona (J.S.-M.) - both in Spain; Karolinska Institute and the Department of Medicine, Division of Hematology, Karolinska University Hospital at Huddinge, Stockholm (H.N.); Tom Baker Cancer Centre, University of Calgary, Calgary, AB (N.J.B.), and the Cancer Clinical Research Unit, Princess Margaret Cancer Centre, Toronto (D.R.) - both in Canada; Levine Cancer Institute-Carolinas HealthCare System, Charlotte, NC (S.Z.U.); the Department of Haematology, University College London Hospitals NHS Trust, London (N.R.); the Department of Lymphoma-Myeloma, University of Texas M.D. Anderson Cancer Center, Houston (R.Z.O.); the Department of Hematology and Stem Cell Transplantation, Poznan University of Medical Sciences, Poznan, Poland (M.K.); the Department of Hematology, Japanese Red Cross Medical Center, Tokyo (K.S.); Vejle Hospital and University of Southern Denmark, Vejle (T.P.), and Genmab, Copenhagen (S.L.) - both in Denmark; the Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea (S.-S.Y.); the Hematology Department, Hadassah-Hebrew University Medical Center, Jerusalem (D.B.Y.); Dana-Farber Cancer Institute, Harvard Medical School, Boston (P.G.R.); University Hospital Heidelberg and the German Cancer Research Center, Heidelberg, Germany (H.G.); Janssen Research and Development, Spring House, PA (N.Z.K., L.O., C.C., X.Q., M.G., T.A.); and the Department of Hematology, University Hospital Hôtel-Dieu, Nantes, France (P.M.).

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http://dx.doi.org/10.1056/NEJMoa1607751DOI Listing
October 2016

Targeted sequencing of refractory myeloma reveals a high incidence of mutations in CRBN and Ras pathway genes.

Blood 2016 09 25;128(9):1226-33. Epub 2016 Jul 25.

Max-Eder Group "Experimental Therapies for Hematologic Malignancies," Heidelberg University Hospital and German Cancer Research Center, Heidelberg, Germany; Department of Internal Medicine V, and.

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http://dx.doi.org/10.1182/blood-2016-02-698092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524534PMC
September 2016

Management of high-risk Myeloma: an evidence-based review of treatment strategies.

Expert Rev Hematol 2016 Aug 4;9(8):753-65. Epub 2016 Jul 4.

a Department of Hematology , University Hospital of Heidelberg , Heidelberg , Germany.

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http://dx.doi.org/10.1080/17474086.2016.1204908DOI Listing
August 2016

Prognostic impact of cytogenetic aberrations in AL amyloidosis patients after high-dose melphalan: a long-term follow-up study.

Blood 2016 07 2;128(4):594-602. Epub 2016 Jun 2.

Amyloidosis Center, and Division of Hematology/Oncology/Rheumatology, Department of Internal Medicine, University of Heidelberg, Heidelberg, Germany;

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http://dx.doi.org/10.1182/blood-2015-10-676361DOI Listing
July 2016