Harry L Malech

Harry L Malech

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Harry L Malech

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Lentiviral Gene Therapy Combined with Low-Dose Busulfan in Infants with SCID-X1.

N Engl J Med 2019 04;380(16):1525-1534

From the Departments of Bone Marrow Transplantation and Cellular Therapy (E.M., B.T., W.J., S.G.), Hematology (S.Z., Z.M., J.C., J.D., X.T., B.Y.R., M.J.W., B.P.S.), Therapeutics Production and Quality (T.L., M.M.M.), Immunology (H.A., B.Y.), Pharmaceutical Sciences (S.J.C.), Biostatistics (G.K., C.L.), and Infectious Diseases (G.M.), St. Jude Children's Research Hospital, Memphis, TN; the Allergy and Clinical Immunology Division, Hospital Nacional Edgardo Rebagliati Martins, Lima, Peru (J.C.A.B.); the Department of Pediatrics, Allergy-Immunology Division, Children's Hospital Los Angeles, Los Angeles (J.A.C.), and the Department of Pediatrics, Division of Pediatric Allergy-Immunology-Bone Marrow Transplantation, University of California, San Francisco (UCSF) Benioff Children's Hospital, San Francisco (J.R.L.-B., J.M.P., M.J.C.) - both in California; the Department of Pediatrics, Pediatric Allergy and Immunology, University of New Mexico, Albuquerque (E.D.); University of Oklahoma Health Sciences Center, Tulsa (J.T.L.); Departamento de Pediatria da Universidade de Taubaté, Conselho Nacional de Medicina, São Paulo (A.C.M.A.); Copperfield Childcare, Claremont, South Africa (H.W.); and the Genetic Immunotherapy Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD (S.S.D.R., H.L.M.).

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http://www.nejm.org/doi/10.1056/NEJMoa1815408
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http://dx.doi.org/10.1056/NEJMoa1815408DOI Listing
April 2019

Addressing the Value of Gene Therapy and Enhancing Patient Access to Transformative Treatments.

Mol Ther 2018 Dec 30;26(12):2717-2726. Epub 2018 Oct 30.

American Society of Gene and Cell Therapy, Milwaukee, WI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2018.10.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277509PMC
December 2018

SCID genotype and 6-month posttransplant CD4 count predict survival and immune recovery.

Blood 2018 Oct 28;132(17):1737-1749. Epub 2018 Aug 28.

Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1182/blood-2018-03-840702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202916PMC
October 2018

Myeloid Conditioning with c-kit-Targeted CAR-T Cells Enables Donor Stem Cell Engraftment.

Mol Ther 2018 05 10;26(5):1181-1197. Epub 2018 Mar 10.

Genetic Immunotherapy Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2018.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993968PMC
May 2018

Future of Care for Patients With Chronic Granulomatous Disease: Gene Therapy and Targeted Molecular Medicine.

J Pediatric Infect Dis Soc 2018 May;7(suppl_1):S40-S44

Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Disease, Bethesda, Maryland.

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http://dx.doi.org/10.1093/jpids/piy011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985732PMC
May 2018

Transition From Pediatric to Adult Care by Young Adults With Chronic Granulomatous Disease: The Patient's Viewpoint.

J Adolesc Health 2017 Dec 22;61(6):716-721. Epub 2017 Sep 22.

Intramural Clinical Management and Operations Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland. Electronic address:

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http://dx.doi.org/10.1016/j.jadohealth.2017.06.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701857PMC
December 2017

Granulocyte transfusions in patients with chronic granulomatous disease and refractory infections: The NIH experience.

J Allergy Clin Immunol 2017 08 22;140(2):622-625. Epub 2017 Mar 22.

Immunology Service, Department of Laboratory Medicine, NIH Clinical Center, National Institutes of Health, Bethesda, Md; Primary Immunodeficiency Clinic, NIAID, National Institutes of Health, Bethesda, Md. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.02.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546986PMC
August 2017

CRISPR-Mediated Knockout of Cybb in NSG Mice Establishes a Model of Chronic Granulomatous Disease for Human Stem-Cell Gene Therapy Transplants.

Hum Gene Ther 2017 07 6;28(7):565-575. Epub 2017 Mar 6.

1 Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases , National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1089/hum.2017.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549813PMC
July 2017

A Novel Method for Screening Adenosine Receptor Specific Agonists for Use in Adenosine Drug Development.

Sci Rep 2017 03 20;7:44816. Epub 2017 Mar 20.

Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda MD 20892, USA.

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http://dx.doi.org/10.1038/srep44816DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357845PMC
March 2017

Interleukin-27 Enhances the Potential of Reactive Oxygen Species Generation from Monocyte-derived Macrophages and Dendritic cells by Induction of p47.

Sci Rep 2017 02 27;7:43441. Epub 2017 Feb 27.

Laboratory of Human Retrovirology and Immunoinformatics, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland 21702, USA.

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http://dx.doi.org/10.1038/srep43441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327488PMC
February 2017

Lentivirus Mediated Correction of Artemis-Deficient Severe Combined Immunodeficiency.

Hum Gene Ther 2017 01 7;28(1):112-124. Epub 2016 Sep 7.

1 Department of Pediatrics, University of California School of Medicine and University of California San Francisco Benioff Children's Hospital , San Francisco, San Francisco, California.

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http://dx.doi.org/10.1089/hum.2016.064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278830PMC
January 2017

Genetic Risk for Inflammatory Bowel Disease Is a Determinant of Crohn's Disease Development in Chronic Granulomatous Disease.

Inflamm Bowel Dis 2016 12;22(12):2794-2801

*Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland; †Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, Maryland; ‡Department of Pediatrics, University of Maryland School of Medicine, Baltimore, Maryland; §Department of Medicine, Meyerhoff Inflammatory Bowel Disease Center, Johns Hopkins University School of Medicine, Baltimore, Maryland; ‖National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health, Bethesda, Maryland; ¶Laboratory of Clinical Infectious Diseases (LCID), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, Maryland; and **Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland.

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http://dx.doi.org/10.1097/MIB.0000000000000966DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303573PMC
December 2016

Thoracic Surgery in Chronic Granulomatous Disease: a 25-Year Single-Institution Experience.

J Clin Immunol 2016 10 6;36(7):677-83. Epub 2016 Aug 6.

Thoracic and Gastrointestinal Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1007/s10875-016-0319-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329290PMC
October 2016

Molecular Analysis of Neutrophil Differentiation from Human Induced Pluripotent Stem Cells Delineates the Kinetics of Key Regulators of Hematopoiesis.

Stem Cells 2016 06 29;34(6):1513-26. Epub 2016 Feb 29.

Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1002/stem.2332DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892955PMC
June 2016

WHIM Syndrome Caused by Waldenström's Macroglobulinemia-Associated Mutation CXCR4 (L329fs).

J Clin Immunol 2016 05 8;36(4):397-405. Epub 2016 Apr 8.

Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bldg. 10, Room 11 N107, Bethesda, MD, 20892-1886, USA.

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http://dx.doi.org/10.1007/s10875-016-0276-3DOI Listing
May 2016

Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease.

Nat Med 2016 Feb 18;22(2):146-53. Epub 2016 Jan 18.

Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health (NIH), Bethesda, Maryland, USA.

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http://dx.doi.org/10.1038/nm.4027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742415PMC
February 2016

Treatment With Anakinra, a Recombinant IL-1 Receptor Antagonist, Unlikely to Induce Lasting Remission in Patients With CGD Colitis.

Am J Gastroenterol 2015 Jun;110(6):938-9

Laboratory of Clinical Infectious Diseases (LCID), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1038/ajg.2015.135DOI Listing
June 2015

An emerging era of clinical benefit from gene therapy.

JAMA 2015 Apr;313(15):1522-3

Department of Pediatrics, University of Washington and Seattle Children's Research Institute, Seattle.

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http://dx.doi.org/10.1001/jama.2015.2055DOI Listing
April 2015

Gene therapy studies in a canine model of X-linked severe combined immunodeficiency.

Hum Gene Ther Clin Dev 2015 Mar 24;26(1):50-6. Epub 2015 Feb 24.

1 Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania , Philadelphia, PA 19104.

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http://dx.doi.org/10.1089/humc.2015.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442583PMC
March 2015

Quantitative shearing linear amplification polymerase chain reaction: an improved method for quantifying lentiviral vector insertion sites in transplanted hematopoietic cell systems.

Hum Gene Ther Methods 2015 Feb 5;26(1):4-12. Epub 2015 Feb 5.

1 Division of Experimental Hematology, Department of Hematology, St. Jude Children's Research Hospital , Memphis, TN 38120.

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http://dx.doi.org/10.1089/hgtb.2014.122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337463PMC
February 2015

Assessment of atherosclerosis in chronic granulomatous disease.

Circulation 2014 Dec 19;130(23):2031-9. Epub 2014 Sep 19.

From the Department of Radiology and Imaging Sciences, National Institutes of Health Clinical Center (C.T.S., A.Z., A.C.K., E.B.T., D.A.B.), Laboratory of Host Defenses (T.E., P.B.S., A.K.R.S., H.L.M., K.A.Z., J.I.G.), Biostatistics Research Branch (C.-Y.H.), and Laboratory of Clinical Infectious Diseases (S.M.H.), National Institute of Allergy and Infectious Diseases and National Heart, Lung, and Blood Institute (A.T.R.), National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.006824DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258873PMC
December 2014

The role of neutrophils in the immune system: an overview.

Methods Mol Biol 2014 ;1124:3-10

Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1007/978-1-62703-845-4_1DOI Listing
October 2014

Generation of functionally mature neutrophils from induced pluripotent stem cells.

Methods Mol Biol 2014 ;1124:189-206

Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

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http://link.springer.com/10.1007/978-1-62703-845-4_12
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http://dx.doi.org/10.1007/978-1-62703-845-4_12DOI Listing
October 2014

Enhancers are major targets for murine leukemia virus vector integration.

J Virol 2014 Apr 5;88(8):4504-13. Epub 2014 Feb 5.

Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1128/JVI.00011-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993722PMC
April 2014

Recurrent erythematous plaques on sun-exposed sites in an African American boy with chronic granulomatous disease.

J Am Acad Dermatol 2014 Mar;70(3):576-80

Dermatology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland. Electronic address:

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http://dx.doi.org/10.1016/j.jaad.2013.09.051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007347PMC
March 2014

Gastrointestinal histopathology in chronic granulomatous disease: a study of 87 patients.

Am J Surg Pathol 2013 Sep;37(9):1365-72

*Laboratory of Pathology, National Cancer Institute, National Institutes of Health †National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases ‡National Institutes of Health, National Cancer Institute §National Institutes of Health, National Institute of Allergy and Infectious Diseases, Bethesda, MD.

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http://dx.doi.org/10.1097/PAS.0b013e318297427dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787986PMC
September 2013

Pyocyanin-enhanced neutrophil extracellular trap formation requires the NADPH oxidase.

PLoS One 2013 14;8(1):e54205. Epub 2013 Jan 14.

Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0054205PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544820PMC
August 2013

B-cell activating factor (BAFF) is elevated in chronic granulomatous disease.

Clin Immunol 2013 Aug 22;148(2):258-64. Epub 2013 May 22.

Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1016/j.clim.2013.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774275PMC
August 2013

Diabetes, renal and cardiovascular disease in p47 phox-/- chronic granulomatous disease.

J Clin Immunol 2013 May 6;33(4):725-30. Epub 2013 Feb 6.

Laboratories of Clinical Infectious Diseases, National Institutes of Health, Bethesda, MD 20892-1684, USA.

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http://dx.doi.org/10.1007/s10875-013-9871-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082696PMC
May 2013

Pegylated siRNA-loaded calcium phosphate nanoparticle-driven amplification of cancer cell internalization in vivo.

Biomaterials 2013 Apr 29;34(12):2980-90. Epub 2013 Jan 29.

Thoracic Oncology Section, Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-1201, USA.

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http://dx.doi.org/10.1016/j.biomaterials.2013.01.046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633203PMC
April 2013

Transgene-free iPSCs generated from small volume peripheral blood nonmobilized CD34+ cells.

Blood 2013 Apr 5;121(14):e98-107. Epub 2013 Feb 5.

Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892-1456, USA.

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http://dx.doi.org/10.1182/blood-2012-03-420273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617640PMC
April 2013

Adenosine A₂A receptor agonist-mediated increase in donor-derived regulatory T cells suppresses development of graft-versus-host disease.

J Immunol 2013 Jan 7;190(1):458-68. Epub 2012 Dec 7.

Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.4049/jimmunol.1201325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674549PMC
January 2013

Gene therapy for chronic granulomatous disease.

Methods Enzymol 2012 ;507:125-54

Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1016/B978-0-12-386509-0.00007-7DOI Listing
June 2012

Corticosteroid therapy for liver abscess in chronic granulomatous disease.

Clin Infect Dis 2012 Mar 9;54(5):694-700. Epub 2011 Dec 9.

Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1093/cid/cir896DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275758PMC
March 2012

Chronic granulomatous disease: overview and hematopoietic stem cell transplantation.

J Allergy Clin Immunol 2011 Jun 17;127(6):1319-26; quiz 1327-8. Epub 2011 Apr 17.

Laboratory of Host Defenses, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1016/j.jaci.2011.03.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133927PMC
June 2011

Oxidase-deficient neutrophils from X-linked chronic granulomatous disease iPS cells: functional correction by zinc finger nuclease-mediated safe harbor targeting.

Blood 2011 May 16;117(21):5561-72. Epub 2011 Mar 16.

Division of Hematology, Department of Medicine, and Stem Cell Program, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1182/blood-2010-12-328161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110021PMC
May 2011

Tryptophan/kynurenine metabolism in human leukocytes is independent of superoxide and is fully maintained in chronic granulomatous disease.

Blood 2010 Sep 28;116(10):1755-60. Epub 2010 May 28.

Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1182/blood-2009-07-233734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947395PMC
September 2010

A self-inactivating lentiviral vector for SCID-X1 gene therapy that does not activate LMO2 expression in human T cells.

Blood 2010 Aug 10;116(6):900-8. Epub 2010 May 10.

Division of Experimental Hematology, Department of Hematology, St Jude Children's Research Hospital, 262 Danny Thomas Pl., Memphis, TN 38105, USA.

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http://dx.doi.org/10.1182/blood-2009-10-250209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924228PMC
August 2010

Impact of CXCR4 inhibition on FLT3-ITD-positive human AML blasts.

Exp Hematol 2010 Mar 24;38(3):180-90. Epub 2009 Dec 24.

Department of Pediatrics, University Clinic Carl Gustav Carus Dresden, Dresden, Germany.

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http://dx.doi.org/10.1016/j.exphem.2009.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777334PMC
March 2010

Adenosine A2A receptor activation limits graft-versus-host disease after allogenic hematopoietic stem cell transplantation.

J Leukoc Biol 2010 Feb 4;87(2):345-54. Epub 2009 Nov 4.

Department of Biology, Lebanon Valley College, Annville, Pennsylvania, USA.

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http://dx.doi.org/10.1189/jlb.0609388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812560PMC
February 2010

Advances in treatment for chronic granulomatous disease.

Immunol Res 2009 ;43(1-3):77-84

National Institutes of Health, Building 10-Room 6-3752, 10 Center Drive, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1007/s12026-008-8051-zDOI Listing
June 2009

Partially corrected X-linked severe combined immunodeficiency: long-term problems and treatment options.

Immunol Res 2009 ;43(1-3):223-42

Genetic Immunotherapy, Laboratory of Host Defense, National Institutes of Health, Building 10, Room 5-3816, 5 West Labs CRC, 10 Center Drive MSC1456, Bethesda, MD 20892-1456, USA.

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http://dx.doi.org/10.1007/s12026-008-8073-6DOI Listing
June 2009

Functional neutrophils from human ES cells.

Blood 2009 Jun;113(26):6503-5

National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1182/blood-2009-04-214320DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2710912PMC
June 2009

WHIM syndrome: congenital immune deficiency disease.

Curr Opin Hematol 2009 Jan;16(1):20-6

Department of Pediatrics, Jikei University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1097/MOH.0b013e32831ac557DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673024PMC
January 2009

Chronic granulomatous disease as a risk factor for autoimmune disease.

J Allergy Clin Immunol 2008 Dec 26;122(6):1097-103. Epub 2008 Sep 26.

National Institutes of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892-1456, USA.

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http://dx.doi.org/10.1016/j.jaci.2008.07.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2786235PMC
December 2008

Rippled skin, fasciitis, and joint contractures.

J Am Acad Dermatol 2008 Dec;59(6):1070-4

Dermatology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892-1908, USA.

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http://dx.doi.org/10.1016/j.jaad.2008.08.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2591931PMC
December 2008

Short stature in partially corrected X-linked severe combined immunodeficiency--suboptimal response to growth hormone.

J Pediatr Endocrinol Metab 2008 Nov;21(11):1057-63

Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases (NIAID), Bethesda, MD 20892, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715294PMC
November 2008

Donor demographic and laboratory predictors of allogeneic peripheral blood stem cell mobilization in an ethnically diverse population.

Blood 2008 Sep 3;112(5):2092-100. Epub 2008 Jun 3.

Department of Transfusion Medicine, Warren Grant Magnuson Clinical Center, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1182/blood-2008-03-143677DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518908PMC
September 2008

The role of neutrophils in the immune system: an overview.

Authors:
Harry L Malech

Methods Mol Biol 2007 ;412:3-11

Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1007/978-1-59745-467-4_1DOI Listing
June 2008

The K-562 cell model for analysis of neutrophil NADPH oxidase function.

Methods Mol Biol 2007 ;412:365-83

Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, USA.

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http://dx.doi.org/10.1007/978-1-59745-467-4_24DOI Listing
June 2008