Publications by authors named "Harry Hemingway"

99Publications

Estimating the effect of reduced attendance at emergency departments for suspected cardiac conditions on cardiac mortality during the COVID-19 pandemic.

Authors:
Michail Katsoulis Manuel Gomes Alvina G Lai Albert Henry Spiros Denaxas Pagona Lagiou Vahe Nafilyan Ben Humberstone Amitava Banerjee Harry Hemingway R Thomas Lumbers

Circ Cardiovasc Qual Outcomes 2020 Dec 20. Epub 2020 Dec 20.

Institute of Health Informatics, University College London, UK; Health Data Research UK London, University College London, UK; Bart's Heart Centre, St. Bartholomew's Hospital, London, UK.

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December 2020

Estimated impact of the COVID-19 pandemic on cancer services and excess 1-year mortality in people with cancer and multimorbidity: near real-time data on cancer care, cancer deaths and a population-based cohort study.

Authors:
Alvina G Lai Laura Pasea Amitava Banerjee Geoff Hall Spiros Denaxas Wai Hoong Chang Michail Katsoulis Bryan Williams Deenan Pillay Mahdad Noursadeghi David Linch Derralynn Hughes Martin D Forster Clare Turnbull Natalie K Fitzpatrick Kathryn Boyd Graham R Foster Tariq Enver Vahe Nafilyan Ben Humberstone Richard D Neal Matt Cooper Monica Jones Kathy Pritchard-Jones Richard Sullivan Charlie Davie Mark Lawler Harry Hemingway

BMJ Open 2020 11 17;10(11):e043828. Epub 2020 Nov 17.

Institute of Health Informatics, University College London, London, UK.

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November 2020

COVID-19 Mortality Risk in Down Syndrome: Results From a Cohort Study Of 8 Million Adults.

Authors:
Ashley Kieran Clift Carol A C Coupland Ruth H Keogh Harry Hemingway Julia Hippisley-Cox

Ann Intern Med 2020 Oct 21. Epub 2020 Oct 21.

University of Oxford, Oxford, United Kingdom (A.K.C., J.H.).

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October 2020

Living risk prediction algorithm (QCOVID) for risk of hospital admission and mortality from coronavirus 19 in adults: national derivation and validation cohort study.

Authors:
Ash K Clift Carol A C Coupland Ruth H Keogh Karla Diaz-Ordaz Elizabeth Williamson Ewen M Harrison Andrew Hayward Harry Hemingway Peter Horby Nisha Mehta Jonathan Benger Kamlesh Khunti David Spiegelhalter Aziz Sheikh Jonathan Valabhji Ronan A Lyons John Robson Malcolm G Semple Frank Kee Peter Johnson Susan Jebb Tony Williams Julia Hippisley-Cox

BMJ 2020 10 20;371:m3731. Epub 2020 Oct 20.

Nuffield Department of Primary Care Health Sciences, Radcliffe Observatory Quarter, Oxford OX2 6GG, UK

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October 2020

Monitoring indirect impact of COVID-19 pandemic on services for cardiovascular diseases in the UK.

Authors:
Simon Ball Amitava Banerjee Colin Berry Jonathan R Boyle Benjamin Bray William Bradlow Afzal Chaudhry Rikki Crawley John Danesh Alastair Denniston Florian Falter Jonine D Figueroa Christopher Hall Harry Hemingway Emily Jefferson Tom Johnson Graham King Kuan Ken Lee Paul McKean Suzanne Mason Nicholas L Mills Ewen Pearson Munir Pirmohamed Michael T C Poon Rouven Priedon Anoop Shah Reecha Sofat Jonathan A C Sterne Fiona E Strachan Cathie L M Sudlow Zsolt Szarka William Whiteley Michael Wyatt

Heart 2020 12 5;106(24):1890-1897. Epub 2020 Oct 5.

University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.

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December 2020

Models for mortality require tailoring in the context of the COVID-19 pandemic - Authors' reply.

Authors:
Amitava Banerjee Laura Pasea Spiros Denaxas Bryan Williams Harry Hemingway

Lancet 2020 09;396(10255):883-884

Institute of Health Informatics, University College London, London NW1 1DA, UK; Health Data Research UK, London, UK.

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September 2020

Corrigendum to: "Genome-wide and Mendelian randomisation studies of liver MRI yield insights into the pathogenesis of steatohepatitis" [J Hepatol (2020) 241-251].

Authors:
Constantinos A Parisinos Henry R Wilman E Louise Thomas Matt Kelly Rowan C Nicholls John McGonigle Stefan Neubauer Aroon D Hingorani Riyaz S Patel Harry Hemingway Jimmy D Bell Rajarshi Banerjee Hanieh Yaghootkar

J Hepatol 2020 Dec 18;73(6):1594-1595. Epub 2020 Sep 18.

Research Centre for Optimal Health, School of Life Sciences, University of Westminster, London, UK; Genetics of Complex Traits, College of Medicine and Health, University of Exeter, Exeter, UK; Division of Medical Sciences, Department of Health Sciences, Luleå University of Technology, Luleå, Sweden. Electronic address:

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December 2020

Invasive versus non-invasive management of older patients with non-ST elevation myocardial infarction (SENIOR-NSTEMI): a cohort study based on routine clinical data.

Authors:
Amit Kaura Jonathan A C Sterne Adam Trickey Sam Abbott Abdulrahim Mulla Benjamin Glampson Vasileios Panoulas Jim Davies Kerrie Woods Joe Omigie Anoop D Shah Keith M Channon Jonathan N Weber Mark R Thursz Paul Elliott Harry Hemingway Bryan Williams Folkert W Asselbergs Michael O'Sullivan Graham M Lord Narbeh Melikian Thomas Johnson Darrel P Francis Ajay M Shah Divaka Perera Rajesh Kharbanda Riyaz S Patel Jamil Mayet

Lancet 2020 08;396(10251):623-634

National Institute for Health Research Imperial Biomedical Research Centre, Imperial College London and Imperial College Healthcare NHS Trust, London, UK. Electronic address:

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August 2020

Clinical academic research in the time of Corona: A simulation study in England and a call for action.

Authors:
Amitava Banerjee Michail Katsoulis Alvina G Lai Laura Pasea Thomas A Treibel Charlotte Manisty Spiros Denaxas Giovanni Quarta Harry Hemingway João L Cavalcante Mahdad Noursadeghi James C Moon

PLoS One 2020 13;15(8):e0237298. Epub 2020 Aug 13.

Barts NHS Trust, London, United Kingdom.

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August 2020

Children with COVID-19 at a specialist centre: initial experience and outcome.

Authors:
Richard W Issitt John Booth William A Bryant Anastasia Spiridou Andrew M Taylor Pascale du Pré Pad Ramnarayan John Hartley Maria Cortina-Borja Karyn Moshal Helen Dunn Harry Hemingway Neil J Sebire

Lancet Child Adolesc Health 2020 08 23;4(8):e30-e31. Epub 2020 Jun 23.

Digital Research and Informatics Unit, Great Ormond Street Hospital and Great Ormond Street Institute of Child Health and NIHR GOSH Biomedical Research Centre, London WC1N 3JH, UK.

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August 2020

Estimating excess 1-year mortality associated with the COVID-19 pandemic according to underlying conditions and age: a population-based cohort study.

Authors:
Amitava Banerjee Laura Pasea Steve Harris Arturo Gonzalez-Izquierdo Ana Torralbo Laura Shallcross Mahdad Noursadeghi Deenan Pillay Neil Sebire Chris Holmes Christina Pagel Wai Keong Wong Claudia Langenberg Bryan Williams Spiros Denaxas Harry Hemingway

Lancet 2020 05 12;395(10238):1715-1725. Epub 2020 May 12.

Institute of Health Informatics, University College London, London, UK; Health Data Research UK, London, UK.

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May 2020

Genome-wide and Mendelian randomisation studies of liver MRI yield insights into the pathogenesis of steatohepatitis.

Authors:
Constantinos A Parisinos Henry R Wilman E Louise Thomas Matt Kelly Rowan C Nicholls John McGonigle Stefan Neubauer Aroon D Hingorani Riyaz S Patel Harry Hemingway Jimmy D Bell Rajarshi Banerjee Hanieh Yaghootkar

J Hepatol 2020 Aug 2;73(2):241-251. Epub 2020 Apr 2.

Research Centre for Optimal Health, School of Life Sciences, University of Westminster, London, UK; Genetics of Complex Traits, College of Medicine and Health, University of Exeter, Exeter, UK; Division of Medical Sciences, Department of Health Sciences, Luleå University of Technology, Luleå, Sweden. Electronic address:

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August 2020

Prognostic significance of troponin level in 3121 patients presenting with atrial fibrillation (The NIHR Health Informatics Collaborative TROP-AF study).

Authors:
Amit Kaura Ahran D Arnold Vasileios Panoulas Benjamin Glampson Jim Davies Abdulrahim Mulla Kerrie Woods Joe Omigie Anoop D Shah Keith M Channon Jonathan N Weber Mark R Thursz Paul Elliott Harry Hemingway Bryan Williams Folkert W Asselbergs Michael O'Sullivan Graham M Lord Narbeh Melikian David C Lefroy Darrel P Francis Ajay M Shah Rajesh Kharbanda Divaka Perera Riyaz S Patel Jamil Mayet

J Am Heart Assoc 2020 04 26;9(7):e013684. Epub 2020 Mar 26.

NIHR Imperial Biomedical Research Centre Imperial College London and Imperial College Healthcare NHS Trust London United Kingdom.

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April 2020

Machine learning and artificial intelligence research for patient benefit: 20 critical questions on transparency, replicability, ethics, and effectiveness.

Authors:
Sebastian Vollmer Bilal A Mateen Gergo Bohner Franz J Király Rayid Ghani Pall Jonsson Sarah Cumbers Adrian Jonas Katherine S L McAllister Puja Myles David Granger Mark Birse Richard Branson Karel G M Moons Gary S Collins John P A Ioannidis Chris Holmes Harry Hemingway

BMJ 2020 03 20;368:l6927. Epub 2020 Mar 20.

Health Data Research UK London, University College London, London, UK.

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March 2020

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure.

Authors:
Sonia Shah Albert Henry Carolina Roselli Honghuang Lin Garðar Sveinbjörnsson Ghazaleh Fatemifar Åsa K Hedman Jemma B Wilk Michael P Morley Mark D Chaffin Anna Helgadottir Niek Verweij Abbas Dehghan Peter Almgren Charlotte Andersson Krishna G Aragam Johan Ärnlöv Joshua D Backman Mary L Biggs Heather L Bloom Jeffrey Brandimarto Michael R Brown Leonard Buckbinder David J Carey Daniel I Chasman Xing Chen Xu Chen Jonathan Chung William Chutkow James P Cook Graciela E Delgado Spiros Denaxas Alexander S Doney Marcus Dörr Samuel C Dudley Michael E Dunn Gunnar Engström Tõnu Esko Stephan B Felix Chris Finan Ian Ford Mohsen Ghanbari Sahar Ghasemi Vilmantas Giedraitis Franco Giulianini John S Gottdiener Stefan Gross Daníel F Guðbjartsson Rebecca Gutmann Christopher M Haggerty Pim van der Harst Craig L Hyde Erik Ingelsson J Wouter Jukema Maryam Kavousi Kay-Tee Khaw Marcus E Kleber Lars Køber Andrea Koekemoer Claudia Langenberg Lars Lind Cecilia M Lindgren Barry London Luca A Lotta Ruth C Lovering Jian'an Luan Patrik Magnusson Anubha Mahajan Kenneth B Margulies Winfried März Olle Melander Ify R Mordi Thomas Morgan Andrew D Morris Andrew P Morris Alanna C Morrison Michael W Nagle Christopher P Nelson Alexander Niessner Teemu Niiranen Michelle L O'Donoghue Anjali T Owens Colin N A Palmer Helen M Parry Markus Perola Eliana Portilla-Fernandez Bruce M Psaty Kenneth M Rice Paul M Ridker Simon P R Romaine Jerome I Rotter Perttu Salo Veikko Salomaa Jessica van Setten Alaa A Shalaby Diane T Smelser Nicholas L Smith Steen Stender David J Stott Per Svensson Mari-Liis Tammesoo Kent D Taylor Maris Teder-Laving Alexander Teumer Guðmundur Thorgeirsson Unnur Thorsteinsdottir Christian Torp-Pedersen Stella Trompet Benoit Tyl Andre G Uitterlinden Abirami Veluchamy Uwe Völker Adriaan A Voors Xiaosong Wang Nicholas J Wareham Dawn Waterworth Peter E Weeke Raul Weiss Kerri L Wiggins Heming Xing Laura M Yerges-Armstrong Bing Yu Faiez Zannad Jing Hua Zhao Harry Hemingway Nilesh J Samani John J V McMurray Jian Yang Peter M Visscher Christopher Newton-Cheh Anders Malarstig Hilma Holm Steven A Lubitz Naveed Sattar Michael V Holmes Thomas P Cappola Folkert W Asselbergs Aroon D Hingorani Karoline Kuchenbaecker Patrick T Ellinor Chim C Lang Kari Stefansson J Gustav Smith Ramachandran S Vasan Daniel I Swerdlow R Thomas Lumbers

Nat Commun 2020 01 9;11(1):163. Epub 2020 Jan 9.

British Heart Foundation Research Accelerator, University College London, London, UK.

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January 2020

Improving the odds of drug development success through human genomics: modelling study.

Authors:
Aroon D Hingorani Valerie Kuan Chris Finan Felix A Kruger Anna Gaulton Sandesh Chopade Reecha Sofat Raymond J MacAllister John P Overington Harry Hemingway Spiros Denaxas David Prieto Juan Pablo Casas

Sci Rep 2019 12 11;9(1):18911. Epub 2019 Dec 11.

Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), Veterans Administration, Boston, MA, USA.

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December 2019

Metformin use and cardiovascular outcomes after acute myocardial infarction in patients with type 2 diabetes: a cohort study.

Authors:
Daniel I Bromage Tom R Godec Mar Pujades-Rodriguez Arturo Gonzalez-Izquierdo S Denaxas Harry Hemingway Derek M Yellon

Cardiovasc Diabetol 2019 12 9;18(1):168. Epub 2019 Dec 9.

The Hatter Cardiovascular Institute, University College London, 67 Chenies Mews, London, WC1E 6HX, UK.

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December 2019

Association of troponin level and age with mortality in 250 000 patients: cohort study across five UK acute care centres.

Authors:
Amit Kaura Vasileios Panoulas Benjamin Glampson Jim Davies Abdulrahim Mulla Kerrie Woods Joe Omigie Anoop D Shah Keith M Channon Jonathan N Weber Mark R Thursz Paul Elliott Harry Hemingway Bryan Williams Folkert W Asselbergs Michael O'Sullivan Rajesh Kharbanda Graham M Lord Narbeh Melikian Riyaz S Patel Divaka Perera Ajay M Shah Darrel P Francis Jamil Mayet

BMJ 2019 11 20;367:l6055. Epub 2019 Nov 20.

NIHR Imperial Biomedical Research Centre, Imperial College London and Imperial College Healthcare NHS Trust, Hammersmith Hospital, London W12 0HS, UK

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November 2019

Bleeding in cardiac patients prescribed antithrombotic drugs: electronic health record phenotyping algorithms, incidence, trends and prognosis.

Authors:
Laura Pasea Sheng-Chia Chung Mar Pujades-Rodriguez Anoop D Shah Samantha Alvarez-Madrazo Victoria Allan James T Teo Daniel Bean Reecha Sofat Richard Dobson Amitava Banerjee Riyaz S Patel Adam Timmis Spiros Denaxas Harry Hemingway

BMC Med 2019 11 20;17(1):206. Epub 2019 Nov 20.

Health Data Research UK, University College London, 222 Euston Road, London, NW1 2DA, UK.

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November 2019

Natural language processing for disease phenotyping in UK primary care records for research: a pilot study in myocardial infarction and death.

Authors:
Anoop D Shah Emily Bailey Tim Williams Spiros Denaxas Richard Dobson Harry Hemingway

J Biomed Semantics 2019 11 12;10(Suppl 1):20. Epub 2019 Nov 12.

Health Data Research UK London, University College London, 222 Euston Road, London, NW1 2DA, UK.

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November 2019

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9.

Authors:
Amand F Schmidt Michael V Holmes David Preiss Daniel I Swerdlow Spiros Denaxas Ghazaleh Fatemifar Rupert Faraway Chris Finan Dennis Valentine Zammy Fairhurst-Hunter Fernando Pires Hartwig Bernardo Lessa Horta Elina Hypponen Christine Power Max Moldovan Erik van Iperen Kees Hovingh Ilja Demuth Kristina Norman Elisabeth Steinhagen-Thiessen Juri Demuth Lars Bertram Christina M Lill Stefan Coassin Johann Willeit Stefan Kiechl Karin Willeit Dan Mason John Wright Richard Morris Goya Wanamethee Peter Whincup Yoav Ben-Shlomo Stela McLachlan Jackie F Price Mika Kivimaki Catherine Welch Adelaida Sanchez-Galvez Pedro Marques-Vidal Andrew Nicolaides Andrie G Panayiotou N Charlotte Onland-Moret Yvonne T van der Schouw Giuseppe Matullo Giovanni Fiorito Simonetta Guarrera Carlotta Sacerdote Nicholas J Wareham Claudia Langenberg Robert A Scott Jian'an Luan Martin Bobak Sofia Malyutina Andrzej Pająk Ruzena Kubinova Abdonas Tamosiunas Hynek Pikhart Niels Grarup Oluf Pedersen Torben Hansen Allan Linneberg Tine Jess Jackie Cooper Steve E Humphries Murray Brilliant Terrie Kitchner Hakon Hakonarson David S Carrell Catherine A McCarty Kirchner H Lester Eric B Larson David R Crosslin Mariza de Andrade Dan M Roden Joshua C Denny Cara Carty Stephen Hancock John Attia Elizabeth Holliday Rodney Scott Peter Schofield Martin O'Donnell Salim Yusuf Michael Chong Guillaume Pare Pim van der Harst M Abdullah Said Ruben N Eppinga Niek Verweij Harold Snieder Tim Christen D O Mook-Kanamori Stefan Gustafsson Lars Lind Erik Ingelsson Raha Pazoki Oscar Franco Albert Hofman Andre Uitterlinden Abbas Dehghan Alexander Teumer Sebastian Baumeister Marcus Dörr Markus M Lerch Uwe Völker Henry Völzke Joey Ward Jill P Pell Tom Meade Ingrid E Christophersen Anke H Maitland-van der Zee Ekaterina V Baranova Robin Young Ian Ford Archie Campbell Sandosh Padmanabhan Michiel L Bots Diederick E Grobbee Philippe Froguel Dorothée Thuillier Ronan Roussel Amélie Bonnefond Bertrand Cariou Melissa Smart Yanchun Bao Meena Kumari Anubha Mahajan Jemma C Hopewell Sudha Seshadri Caroline Dale Rui Providencia E Costa Paul M Ridker Daniel I Chasman Alex P Reiner Marylyn D Ritchie Leslie A Lange Alex J Cornish Sara E Dobbins Kari Hemminki Ben Kinnersley Marc Sanson Karim Labreche Matthias Simon Melissa Bondy Philip Law Helen Speedy James Allan Ni Li Molly Went Niels Weinhold Gareth Morgan Pieter Sonneveld Björn Nilsson Hartmut Goldschmidt Amit Sud Andreas Engert Markus Hansson Harry Hemingway Folkert W Asselbergs Riyaz S Patel Brendan J Keating Naveed Sattar Richard Houlston Juan P Casas Aroon D Hingorani

BMC Cardiovasc Disord 2019 10 29;19(1):240. Epub 2019 Oct 29.

Institute of Cardiovascular Science, University College London, 222 Euston Road, London, NW1 2DA, UK.

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October 2019

A chronological map of 308 physical and mental health conditions from 4 million individuals in the English National Health Service.

Authors:
Valerie Kuan Spiros Denaxas Arturo Gonzalez-Izquierdo Kenan Direk Osman Bhatti Shanaz Husain Shailen Sutaria Melanie Hingorani Dorothea Nitsch Constantinos A Parisinos R Thomas Lumbers Rohini Mathur Reecha Sofat Juan P Casas Ian C K Wong Harry Hemingway Aroon D Hingorani

Lancet Digit Health 2019 06 20;1(2):e63-e77. Epub 2019 May 20.

Institute of Cardiovascular Science, London.

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June 2019

Evaluation of the impact of the GRACE risk score on the management and outcome of patients hospitalised with non-ST elevation acute coronary syndrome in the UK: protocol of the UKGRIS cluster-randomised registry-based trial.

Authors:
Colin C Everett Keith Aa Fox Catherine Reynolds Catherine Fernandez Linda Sharples Deborah D Stocken Kathryn Carruthers Harry Hemingway Andrew T Yan Shaun G Goodman David Brieger Derek P Chew Chris P Gale

BMJ Open 2019 09 5;9(9):e032165. Epub 2019 Sep 5.

Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.

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September 2019

Global health competencies in UK postgraduate medical training: a scoping review and curricular content analysis.

Authors:
Nader Al-Shakarchi Lucy Obolensky Sarah Walpole Harry Hemingway Amitava Banerjee

BMJ Open 2019 08 24;9(8):e027577. Epub 2019 Aug 24.

Institute of Health Informatics, University College London, London, UK

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August 2019

Diagnosis and treatment for hyperuricemia and gout: a systematic review of clinical practice guidelines and consensus statements.

Authors:
Qianrui Li Xiaodan Li Jing Wang Hongdie Liu Joey Sum-Wing Kwong Hao Chen Ling Li Sheng-Chia Chung Anoop Shah Yaolong Chen Zhenmei An Xin Sun Harry Hemingway Haoming Tian Sheyu Li

BMJ Open 2019 08 24;9(8):e026677. Epub 2019 Aug 24.

Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, China

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August 2019

Subtypes of atrial fibrillation with concomitant valvular heart disease derived from electronic health records: phenotypes, population prevalence, trends and prognosis.

Authors:
Amitava Banerjee Victoria Allan Spiros Denaxas Anoop Shah Dipak Kotecha Pier D Lambiase Jacob Joseph Lars H Lund Harry Hemingway

Europace 2019 12;21(12):1776-1784

Institute of Health Informatics, University College London, 222 Euston Road, London NW1 2DA, UK.

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December 2019

Statistics on mortality following acute myocardial infarction in 842 897 Europeans.

Authors:
Oras A Alabas Tomas Jernberg Mar Pujades-Rodriguez Mark J Rutherford Robert M West Marlous Hall Adam Timmis Bertil Lindahl Keith A A Fox Harry Hemingway Chris P Gale

Cardiovasc Res 2020 01;116(1):149-157

Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.

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January 2020

Phenotyping UK Electronic Health Records from 15 Million Individuals for Precision Medicine: The CALIBER Resource.

Authors:
Spiros Denaxas Arturo Gonzalez-Izquierdo Natalie Fitzpatrick Kenan Direk Harry Hemingway

Stud Health Technol Inform 2019 Jul;262:220-223

Institute of Health Informatics, University College London, United Kingdom.

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July 2019

UK phenomics platform for developing and validating electronic health record phenotypes: CALIBER.

Authors:
Spiros Denaxas Arturo Gonzalez-Izquierdo Kenan Direk Natalie K Fitzpatrick Ghazaleh Fatemifar Amitava Banerjee Richard J B Dobson Laurence J Howe Valerie Kuan R Tom Lumbers Laura Pasea Riyaz S Patel Anoop D Shah Aroon D Hingorani Cathie Sudlow Harry Hemingway

J Am Med Inform Assoc 2019 12;26(12):1545-1559

Institute of Health Informatics, University College London, London,United Kingdom.

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December 2019

Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration.

Authors:
Henry R Wilman Constantinos A Parisinos Naeimeh Atabaki-Pasdar Matt Kelly E Louise Thomas Stefan Neubauer Anubha Mahajan Aroon D Hingorani Riyaz S Patel Harry Hemingway Paul W Franks Jimmy D Bell Rajarshi Banerjee Hanieh Yaghootkar

J Hepatol 2019 09 19;71(3):594-602. Epub 2019 Jun 19.

Research Centre for Optimal Health, School of Life Sciences, University of Westminster, London, UK; Genetics of Complex Traits, College of Medicine and Health, University of Exeter, Exeter, UK. Electronic address:

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September 2019

Author Correction: Towards a data-integrated cell.

Authors:
Noël Malod-Dognin Julia Petschnigg Sam F L Windels Janez Povh Harry Hemingway Robin Ketteler Nataša Pržulj

Nat Commun 2019 May 21;10(1):2324. Epub 2019 May 21.

Department of Computer Science, University College London, London, WC1E 6BT, UK.

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May 2019

Identifying clinically important COPD sub-types using data-driven approaches in primary care population based electronic health records.

Authors:
Maria Pikoula Jennifer Kathleen Quint Francis Nissen Harry Hemingway Liam Smeeth Spiros Denaxas

BMC Med Inform Decis Mak 2019 04 18;19(1):86. Epub 2019 Apr 18.

Institute of Health Informatics, University College London, 222 Euston Road, London, NW1 2DA, UK.

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April 2019

Health informatics competencies in postgraduate medical education and training in the UK: a mixed methods study.

Authors:
Lydia Jidkov Matthew Alexander Pippa Bark John G Williams Jonathan Kay Paul Taylor Harry Hemingway Amitava Banerjee

BMJ Open 2019 03 30;9(3):e025460. Epub 2019 Mar 30.

Institute of Health Informatics, University College London, London, UK.

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March 2019

Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events.

Authors:
Riyaz S Patel Amand F Schmidt Vinicius Tragante Raymond O McCubrey Michael V Holmes Laurence J Howe Kenan Direk Axel Åkerblom Karin Leander Salim S Virani Karol A Kaminski Jochen D Muehlschlegel Marie-Pierre Dubé Hooman Allayee Peter Almgren Maris Alver Ekaterina V Baranova Hassan Behlouli Bram Boeckx Peter S Braund Lutz P Breitling Graciela Delgado Nubia E Duarte Line Dufresne Niclas Eriksson Luisa Foco Crystel M Gijsberts Yan Gong Jaana Hartiala Mahyar Heydarpour Jaroslav A Hubacek Marcus Kleber Daniel Kofink Pekka Kuukasjärvi Vei-Vei Lee Andreas Leiherer Petra A Lenzini Daniel Levin Leo-Pekka Lyytikäinen Nicola Martinelli Ute Mons Christopher P Nelson Kjell Nikus Anna P Pilbrow Rafal Ploski Yan V Sun Michael W T Tanck W H Wilson Tang Stella Trompet Sander W van der Laan Jessica van Setten Ragnar O Vilmundarson Chiara Viviani Anselmi Efthymia Vlachopoulou Eric Boerwinkle Carlo Briguori John F Carlquist Kathryn F Carruthers Gavino Casu John Deanfield Panos Deloukas Frank Dudbridge Natalie Fitzpatrick Bruna Gigante Stefan James Marja-Liisa Lokki Paulo A Lotufo Nicola Marziliano Ify R Mordi Joseph B Muhlestein Chris Newton Cheh Jan Pitha Christoph H Saely Ayman Samman-Tahhan Pratik B Sandesara Andrej Teren Adam Timmis Frans Van de Werf Els Wauters Arthur A M Wilde Ian Ford David J Stott Ale Algra Maria G Andreassi Diego Ardissino Benoit J Arsenault Christie M Ballantyne Thomas O Bergmeijer Connie R Bezzina Simon C Body Peter Bogaty Gert J de Borst Hermann Brenner Ralph Burkhardt Clara Carpeggiani Gianluigi Condorelli Rhonda M Cooper-DeHoff Sharon Cresci Ulf de Faire Robert N Doughty Heinz Drexel James C Engert Keith A A Fox Domenico Girelli Emil Hagström Stanley L Hazen Claes Held Harry Hemingway Imo E Hoefer G Kees Hovingh Julie A Johnson Pim A de Jong J Wouter Jukema Marcin P Kaczor Mika Kähönen Jiri Kettner Marek Kiliszek Olaf H Klungel Bo Lagerqvist Diether Lambrechts Jari O Laurikka Terho Lehtimäki Daniel Lindholm Bakhtawar K Mahmoodi Anke H Maitland-van der Zee Ruth McPherson Olle Melander Andres Metspalu Witold Pepinski Oliviero Olivieri Grzegorz Opolski Colin N Palmer Gerard Pasterkamp Carl J Pepine Alexandre C Pereira Louise Pilote Arshed A Quyyumi A Mark Richards Marek Sanak Markus Scholz Agneta Siegbahn Juha Sinisalo J Gustav Smith John A Spertus Alexandre F R Stewart Wojciech Szczeklik Anna Szpakowicz Jurriën M Ten Berg George Thanassoulis Joachim Thiery Yolanda van der Graaf Frank L J Visseren Johannes Waltenberger Pim Van der Harst Jean-Claude Tardif Naveed Sattar Chim C Lang Guillaume Pare James M Brophy Jeffrey L Anderson Winfried März Lars Wallentin Vicky A Cameron Benjamin D Horne Nilesh J Samani Aroon D Hingorani Folkert W Asselbergs

Circ Genom Precis Med 2019 04 21;12(4):e002471. Epub 2019 Mar 21.

Institute of Cardiovascular Science, Faculty of Population Health Science (R.S.P., A.F.S., L.J.H., K.D., J.D., A.D.H., F.W.A.).

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April 2019

Subsequent Event Risk in Individuals With Established Coronary Heart Disease.

Authors:
Riyaz S Patel Vinicius Tragante Amand F Schmidt Raymond O McCubrey Michael V Holmes Laurence J Howe Kenan Direk Axel Åkerblom Karin Leander Salim S Virani Karol A Kaminski Jochen D Muehlschlegel Hooman Allayee Peter Almgren Maris Alver Ekaterina V Baranova Hassan Behloui Bram Boeckx Peter S Braund Lutz P Breitling Graciela Delgado Nubia E Duarte Marie-Pierre Dubé Line Dufresne Niclas Eriksson Luisa Foco Markus Scholz Crystel M Gijsberts Charlotte Glinge Yan Gong Jaana Hartiala Mahyar Heydarpour Jaroslav A Hubacek Marcus Kleber Daniel Kofink Salma Kotti Pekka Kuukasjärvi Vei-Vei Lee Andreas Leiherer Petra A Lenzini Daniel Levin Leo-Pekka Lyytikäinen Nicola Martinelli Ute Mons Christopher P Nelson Kjell Nikus Anna P Pilbrow Rafal Ploski Yan V Sun Michael W T Tanck W H Wilson Tang Stella Trompet Sander W van der Laan Jessica Van Setten Ragnar O Vilmundarson Chiara Viviani Anselmi Efthymia Vlachopoulou Lawien Al Ali Eric Boerwinkle Carlo Briguori John F Carlquist Kathryn F Carruthers Gavino Casu John Deanfield Panos Deloukas Frank Dudbridge Thomas Engstrøm Natalie Fitzpatrick Kim Fox Bruna Gigante Stefan James Marja-Liisa Lokki Paulo A Lotufo Nicola Marziliano Ify R Mordi Joseph B Muhlestein Christopher Newton-Cheh Jan Pitha Christoph H Saely Ayman Samman-Tahhan Pratik B Sandesara Andrej Teren Adam Timmis Frans Van de Werf Els Wauters Arthur A M Wilde Ian Ford David J Stott Ale Algra Maria G Andreassi Diego Ardissino Benoit J Arsenault Christie M Ballantyne Thomas O Bergmeijer Connie R Bezzina Simon C Body Eric H Boersma Peter Bogaty Michiel L Bots Hermann Brenner Jasper J Brugts Ralph Burkhardt Clara Carpeggiani Gianluigi Condorelli Rhonda M Cooper-DeHoff Sharon Cresci Nicolas Danchin Ulf de Faire Robert N Doughty Heinz Drexel James C Engert Keith A A Fox Domenico Girelli Diederick E Grobbee Emil Hagström Stanley L Hazen Claes Held Harry Hemingway Imo E Hoefer G Kees Hovingh Reza Jabbari Julie A Johnson J Wouter Jukema Marcin P Kaczor Mika Kähönen Jiri Kettner Marek Kiliszek Olaf H Klungel Bo Lagerqvist Diether Lambrechts Jari O Laurikka Terho Lehtimäki Daniel Lindholm B K Mahmoodi Anke H Maitland-van der Zee Ruth McPherson Olle Melander Andres Metspalu Anna Niemcunowicz-Janica Oliviero Olivieri Grzegorz Opolski Colin N Palmer Gerard Pasterkamp Carl J Pepine Alexandre C Pereira Louise Pilote Arshed A Quyyumi A Mark Richards Marek Sanak Agneta Siegbahn Tabassome Simon Juha Sinisalo J Gustav Smith John A Spertus Steen Stender Alexandre F R Stewart Wojciech Szczeklik Anna Szpakowicz Jean-Claude Tardif Jurriën M Ten Berg Jacob Tfelt-Hansen George Thanassoulis Joachim Thiery Christian Torp-Pedersen Yolanda van der Graaf Frank L J Visseren Johannes Waltenberger Peter E Weeke Pim Van der Harst Chim C Lang Naveed Sattar Vicky A Cameron Jeffrey L Anderson James M Brophy Guillaume Pare Benjamin D Horne Winfried März Lars Wallentin Nilesh J Samani Aroon D Hingorani Folkert W Asselbergs

Circ Genom Precis Med 2019 04 21;12(4):e002470. Epub 2019 Mar 21.

Institute of Health Informatics (N.F., A. Timmis, H.H., F.W.A.), Faculty of Population Health Science, University College London, United Kingdom.

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April 2019

Million Migrants study of healthcare and mortality outcomes in non-EU migrants and refugees to England: Analysis protocol for a linked population-based cohort study of 1.5 million migrants.

Authors:
Rachel Burns Neha Pathak Ines Campos-Matos Dominik Zenner Srinivasa Vittal Katikireddi Morris C Muzyamba J Jaime Miranda Ruth Gilbert Harry Rutter Lucy Jones Elizabeth Williamson Andrew C Hayward Liam Smeeth Ibrahim Abubakar Harry Hemingway Robert W Aldridge

Wellcome Open Res 2019 17;4. Epub 2019 Jan 17.

Centre for Public Health Data Science, University College London, London, UK.

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January 2019

Towards a data-integrated cell.

Authors:
Noël Malod-Dognin Julia Petschnigg Sam F L Windels Janez Povh Harry Hemingway Robin Ketteler Nataša Pržulj

Nat Commun 2019 02 18;10(1):805. Epub 2019 Feb 18.

Department of Computer Science, University College London, London, WC1E 6BT, UK.

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February 2019

Risk factors for incident heart failure in age- and sex-specific strata: a population-based cohort using linked electronic health records.

Authors:
Alicia Uijl Stefan Koudstaal Kenan Direk Spiros Denaxas Rolf H H Groenwold Amitava Banerjee Arno W Hoes Harry Hemingway Folkert W Asselbergs

Eur J Heart Fail 2019 10 7;21(10):1197-1206. Epub 2019 Jan 7.

Farr Institute of Health Informatics Research, Institute of Health Informatics, University College London, London, UK.

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October 2019

Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults: Implications for Primary Prevention.

Authors:
Michael Inouye Gad Abraham Christopher P Nelson Angela M Wood Michael J Sweeting Frank Dudbridge Florence Y Lai Stephen Kaptoge Marta Brozynska Tingting Wang Shu Ye Thomas R Webb Martin K Rutter Ioanna Tzoulaki Riyaz S Patel Ruth J F Loos Bernard Keavney Harry Hemingway John Thompson Hugh Watkins Panos Deloukas Emanuele Di Angelantonio Adam S Butterworth John Danesh Nilesh J Samani

J Am Coll Cardiol 2018 10;72(16):1883-1893

Department of Cardiovascular Sciences and NIHR Leicester Biomedical Centre, University of Leicester, Leicester, United Kingdom. Electronic address:

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October 2018

Guideline-indicated treatments and diagnostics, GRACE risk score, and survival for non-ST elevation myocardial infarction.

Authors:
Marlous Hall Owen J Bebb Tatandashe B Dondo Andrew T Yan Shaun G Goodman Hector Bueno Derek P Chew David Brieger Philip D Batin Michel E Farkouh Harry Hemingway Adam Timmis Keith A A Fox Chris P Gale

Eur Heart J 2018 11;39(42):3798-3806

Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Worsley Building, Level 11, Clarendon Way, Leeds, UK.

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November 2018

Time spent at blood pressure target and the risk of death and cardiovascular diseases.

Authors:
Sheng-Chia Chung Mar Pujades-Rodriguez Bram Duyx Spiros C Denaxas Laura Pasea Aroon Hingorani Adam Timmis Bryan Williams Harry Hemingway

PLoS One 2018 5;13(9):e0202359. Epub 2018 Sep 5.

Health Data Research UK London, University College London, London, United Kingdom.

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February 2019

Machine learning models in electronic health records can outperform conventional survival models for predicting patient mortality in coronary artery disease.

Authors:
Andrew J Steele Spiros C Denaxas Anoop D Shah Harry Hemingway Nicholas M Luscombe

PLoS One 2018 31;13(8):e0202344. Epub 2018 Aug 31.

The Francis Crick Institute, London, United Kingdom.

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February 2019

Correction: The diagnosis, burden and prognosis of dementia: A record-linkage cohort study in England.

Authors:
Mar Pujades-Rodriguez Valentina Assi Arturo Gonzalez-Izquierdo Tim Wilkinson Christian Schnier Cathie Sudlow Harry Hemingway William N Whiteley

PLoS One 2018 19;13(7):e0201213. Epub 2018 Jul 19.

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July 2018

Clinically recorded heart rate and incidence of 12 coronary, cardiac, cerebrovascular and peripheral arterial diseases in 233,970 men and women: A linked electronic health record study.

Authors:
Olga Archangelidi Mar Pujades-Rodriguez Adam Timmis Xavier Jouven Spiros Denaxas Harry Hemingway

Eur J Prev Cardiol 2018 09 2;25(14):1485-1495. Epub 2018 Jul 2.

1 Institute of Health Informatics, University College London.

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September 2018

'Who does this patient belong to?' boundary work and the re/making of (NSTEMI) heart attack patients.

Authors:
Helen Cramer Jacki Hughes Rachel Johnson Maggie Evans Christi Deaton Adam Timmis Harry Hemingway Gene Feder Katie Featherstone

Sociol Health Illn 2018 11 28;40(8):1404-1429. Epub 2018 Jun 28.

School of Healthcare Sciences, Cardiff University, Cardiff, UK.

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November 2018

The diagnosis, burden and prognosis of dementia: A record-linkage cohort study in England.

Authors:
Mar Pujades-Rodriguez Valentina Assi Arturo Gonzalez-Izquierdo Tim Wilkinson Christian Schnier Cathie Sudlow Harry Hemingway William N Whiteley

PLoS One 2018 26;13(6):e0199026. Epub 2018 Jun 26.

Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.

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January 2019

Evaluation of Semantic Web Technologies for Storing Computable Definitions of Electronic Health Records Phenotyping Algorithms.

Authors:
Václav Papež Spiros Denaxas Harry Hemingway

AMIA Annu Symp Proc 2017 16;2017:1352-1361. Epub 2018 Apr 16.

Institute of Health Informatics, University College London, London, UK.

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April 2019

Variation in Interleukin 6 Receptor Gene Associates With Risk of Crohn's Disease and Ulcerative Colitis.

Authors:
Constantinos A Parisinos Stylianos Serghiou Michail Katsoulis Marc Jonathan George Riyaz S Patel Harry Hemingway Aroon D Hingorani

Gastroenterology 2018 08 5;155(2):303-306.e2. Epub 2018 Jul 5.

Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, UK.

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August 2018

Socioeconomic disparities in first stroke incidence, quality of care, and survival: a nationwide registry-based cohort study of 44 million adults in England.

Authors:
Benjamin D Bray Lizz Paley Alex Hoffman Martin James Patrick Gompertz Charles D A Wolfe Harry Hemingway Anthony G Rudd

Lancet Public Health 2018 04 15;3(4):e185-e193. Epub 2018 Mar 15.

School of Population Health & Environmental Sciences, King's College London, London, UK.

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April 2018

Multimorbidity and survival for patients with acute myocardial infarction in England and Wales: Latent class analysis of a nationwide population-based cohort.

Authors:
Marlous Hall Tatendashe B Dondo Andrew T Yan Mamas A Mamas Adam D Timmis John E Deanfield Tomas Jernberg Harry Hemingway Keith A A Fox Chris P Gale

PLoS Med 2018 03 6;15(3):e1002501. Epub 2018 Mar 6.

Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom.

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March 2018

An electronic health records cohort study on heart failure following myocardial infarction in England: incidence and predictors.

Authors:
Johannes M I H Gho Amand F Schmidt Laura Pasea Stefan Koudstaal Mar Pujades-Rodriguez Spiros Denaxas Anoop D Shah Riyaz S Patel Chris P Gale Arno W Hoes John G Cleland Harry Hemingway Folkert W Asselbergs

BMJ Open 2018 03 3;8(3):e018331. Epub 2018 Mar 3.

Farr Institute of Health Informatics Research, UCL Institute of Health Informatics, University College London, London, UK.

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March 2018

Big data from electronic health records for early and late translational cardiovascular research: challenges and potential.

Authors:
Harry Hemingway Folkert W Asselbergs John Danesh Richard Dobson Nikolaos Maniadakis Aldo Maggioni Ghislaine J M van Thiel Maureen Cronin Gunnar Brobert Panos Vardas Stefan D Anker Diederick E Grobbee Spiros Denaxas

Eur Heart J 2018 04;39(16):1481-1495

Research Department of Clinical Epidemiology, The Farr Institute of Health Informatics Research, University College London, 222 Euston Road, London NW1 2DA, UK.

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April 2018

Identifying unmet clinical need in hypertrophic cardiomyopathy using national electronic health records.

Authors:
Mar Pujades-Rodriguez Oliver P Guttmann Arturo Gonzalez-Izquierdo Bram Duyx Constantinos O'Mahony Perry Elliott Harry Hemingway

PLoS One 2018 11;13(1):e0191214. Epub 2018 Jan 11.

Farr Institute of Health Informatics Research, Institute of Health Informatics, University College London, London, United Kingdom.

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February 2018

Temporal trends and patterns in heart failure incidence: a population-based study of 4 million individuals.

Authors:
Nathalie Conrad Andrew Judge Jenny Tran Hamid Mohseni Deborah Hedgecott Abel Perez Crespillo Moira Allison Harry Hemingway John G Cleland John J V McMurray Kazem Rahimi

Lancet 2018 02 21;391(10120):572-580. Epub 2017 Nov 21.

The George Institute for Global Health, University of Oxford, Oxford, UK; Deep Medicine, Oxford Martin School, University of Oxford, Oxford, UK; Oxford University Hospitals NHS Foundation Trust, Oxford, UK. Electronic address:

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February 2018

What happens to work capacity after coronary revascularization?

Authors:
Mika Kivimäki Jane E Ferrie Harry Hemingway

Eur Heart J Qual Care Clin Outcomes 2017 04;3(2):95-96

Farr Institute of Health Informatics Research, Institute of Health Informatics, University College London, 222 Euston Road, London NW1 2DA, UK.

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April 2017

Methods for enhancing the reproducibility of biomedical research findings using electronic health records.

Authors:
Spiros Denaxas Kenan Direk Arturo Gonzalez-Izquierdo Maria Pikoula Aylin Cakiroglu Jason Moore Harry Hemingway Liam Smeeth

BioData Min 2017 11;10:31. Epub 2017 Sep 11.

EHR Research Group, Department of Non-communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, Keppel Streeet, London, WC1E 7HT UK.

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September 2017

Reply: Neutrophil Count Is Associated With Risks of Cardiovascular Diseases.

Authors:
Anoop Dinesh Shah Spiros Denaxas Owen Nicholas Aroon D Hingorani Harry Hemingway

J Am Coll Cardiol 2017 08;70(7):912

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August 2017

Ethnicity and the first diagnosis of a wide range of cardiovascular diseases: Associations in a linked electronic health record cohort of 1 million patients.

Authors:
Julie George Rohini Mathur Anoop Dinesh Shah Mar Pujades-Rodriguez Spiros Denaxas Liam Smeeth Adam Timmis Harry Hemingway

PLoS One 2017 9;12(6):e0178945. Epub 2017 Jun 9.

The Farr Institute of Health Informatics Research and the National Institute for Health Research, Biomedical Research Centre, University College London, London, United Kingdom.

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September 2017

β-Blockers and Mortality After Acute Myocardial Infarction in Patients Without Heart Failure or Ventricular Dysfunction.

Authors:
Tatendashe B Dondo Marlous Hall Robert M West Tomas Jernberg Bertil Lindahl Hector Bueno Nicolas Danchin John E Deanfield Harry Hemingway Keith A A Fox Adam D Timmis Chris P Gale

J Am Coll Cardiol 2017 Jun;69(22):2710-2720

Medical Research Council Bioinformatics Centre, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom; Department of Cardiology, York Teaching Hospital NHS Foundation Trust, York, United Kingdom. Electronic address:

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June 2017

Evaluation of Machine Learning Methods to Predict Coronary Artery Disease Using Metabolomic Data.

Authors:
Henrietta Forssen Riyaz Patel Natalie Fitzpatrick Aroon Hingorani Adam Timmis Harry Hemingway Spiros Denaxas

Stud Health Technol Inform 2017 ;235:111-115

Institute of Health Informatics, UCL.

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October 2017

Prognosis of undiagnosed chest pain: linked electronic health record cohort study.

Authors:
Kelvin P Jordan Adam Timmis Peter Croft Danielle A van der Windt Spiros Denaxas Arturo González-Izquierdo Richard A Hayward Pablo Perel Harry Hemingway

BMJ 2017 Apr 3;357:j1194. Epub 2017 Apr 3.

Farr Institute of Health Informatics Research London, Institute of Health Informatics, University College London, London, UK.

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April 2017

Association between clinically recorded alcohol consumption and initial presentation of 12 cardiovascular diseases: population based cohort study using linked health records.

Authors:
Steven Bell Marina Daskalopoulou Eleni Rapsomaniki Julie George Annie Britton Martin Bobak Juan P Casas Caroline E Dale Spiros Denaxas Anoop D Shah Harry Hemingway

BMJ 2017 Mar 22;356:j909. Epub 2017 Mar 22.

Farr Institute of Health Informatics Research (London), University College London, London NW1 2DA, UK.

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March 2017

Personalising the decision for prolonged dual antiplatelet therapy: development, validation and potential impact of prognostic models for cardiovascular events and bleeding in myocardial infarction survivors.

Authors:
Laura Pasea Sheng-Chia Chung Mar Pujades-Rodriguez Alireza Moayyeri Spiros Denaxas Keith A A Fox Lars Wallentin Stuart J Pocock Adam Timmis Amitava Banerjee Riyaz Patel Harry Hemingway

Eur Heart J 2017 04;38(14):1048-1055

The Farr Institute of Health Informatics Research, University College London, London, UK.

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April 2017

Neutrophil Counts and Initial Presentation of 12 Cardiovascular Diseases: A CALIBER Cohort Study.

Authors:
Anoop Dinesh Shah Spiros Denaxas Owen Nicholas Aroon D Hingorani Harry Hemingway

J Am Coll Cardiol 2017 Mar;69(9):1160-1169

Farr Institute of Health Informatics Research, UCL Institute of Health Informatics, University College London, London, United Kingdom.

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March 2017

Developing and validating a cardiovascular risk score for patients in the community with prior cardiovascular disease.

Authors:
Katrina K Poppe Rob N Doughty Sue Wells Dudley Gentles Harry Hemingway Rod Jackson Andrew J Kerr

Heart 2017 06 23;103(12):891-892. Epub 2017 Feb 23.

School of Population Health, University of Auckland, Auckland, New Zealand.

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June 2017

Are cardiovascular risk factors also associated with the incidence of atrial fibrillation? A systematic review and field synopsis of 23 factors in 32 population-based cohorts of 20 million participants.

Authors:
Victoria Allan Shohreh Honarbakhsh Juan-Pablo Casas Joshua Wallace Ross Hunter Richard Schilling Pablo Perel Katherine Morley Amitava Banerjee Harry Hemingway

Thromb Haemost 2017 05 23;117(5):837-850. Epub 2017 Feb 23.

Prof. Harry Hemingway, Farr Institute of Health Informatics Research, University College London, 222 Euston Road, London NW1 2AD, UK, Tel.: +44 20 35495329, E-mail:

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May 2017

White cell count in the normal range and short-term and long-term mortality: international comparisons of electronic health record cohorts in England and New Zealand.

Authors:
Anoop Dinesh Shah Simon Thornley Sheng-Chia Chung Spiros Denaxas Rod Jackson Harry Hemingway

BMJ Open 2017 02 17;7(2):e013100. Epub 2017 Feb 17.

Farr Institute of Health Informatics Research, UCL Institute of Health Informatics, London, UK.

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February 2017

Aligning the planets: The role of nurses in the care of patients with non-ST elevation myocardial infarction.

Authors:
Christi Deaton Rachel Johnson Maggie Evans Adam Timmis Justin Zaman Harry Hemingway Jacqueline Hughes Gene Feder Helen Cramer

Nurs Open 2017 01 4;4(1):49-56. Epub 2016 Nov 4.

Centre for Academic Primary Care School of Social and Community Medicine University of Bristol Bristol UK.

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January 2017

Prognostic burden of heart failure recorded in primary care, acute hospital admissions, or both: a population-based linked electronic health record cohort study in 2.1 million people.

Authors:
Stefan Koudstaal Mar Pujades-Rodriguez Spiros Denaxas Johannes M I H Gho Anoop D Shah Ning Yu Riyaz S Patel Chris P Gale Arno W Hoes John G Cleland Folkert W Asselbergs Harry Hemingway

Eur J Heart Fail 2017 09 23;19(9):1119-1127. Epub 2016 Dec 23.

Farr Institute of Health Informatics Research, London, UK.

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September 2017

Low eosinophil and low lymphocyte counts and the incidence of 12 cardiovascular diseases: a CALIBER cohort study.

Authors:
Anoop Dinesh Shah Spiros Denaxas Owen Nicholas Aroon D Hingorani Harry Hemingway

Open Heart 2016;3(2):e000477. Epub 2016 Sep 5.

Farr Institute of Health Informatics Research, UCL Institute of Health Informatics, University College London , London , UK.

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September 2016

Net clinical benefit of warfarin in individuals with atrial fibrillation across stroke risk and across primary and secondary care.

Authors:
Victoria Allan Amitava Banerjee Anoop Dinesh Shah Riyaz Patel Spiros Denaxas Juan-Pablo Casas Harry Hemingway

Heart 2017 02 31;103(3):210-218. Epub 2016 Aug 31.

Farr Institute of Health Informatics Research, Institute of Health Informatics, University College London, London, UK.

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February 2017

Association of Clinical Factors and Therapeutic Strategies With Improvements in Survival Following Non-ST-Elevation Myocardial Infarction, 2003-2013.

Authors:
Marlous Hall Tatendashe B Dondo Andrew T Yan Shaun G Goodman Héctor Bueno Derek P Chew David Brieger Adam Timmis Phillip D Batin John E Deanfield Harry Hemingway Keith A A Fox Christopher P Gale

JAMA 2016 Sep;316(10):1073-82

Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, England14York Teaching Hospital NHS Foundation Trust, York, England.

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September 2016

Editor's Choice - Impact of initial hospital diagnosis on mortality for acute myocardial infarction: A national cohort study.

Authors:
Jianhua Wu Chris P Gale Marlous Hall Tatendashe B Dondo Elizabeth Metcalfe Ged Oliver Phil D Batin Harry Hemingway Adam Timmis Robert M West

Eur Heart J Acute Cardiovasc Care 2018 Mar 29;7(2):139-148. Epub 2016 Aug 29.

8 Leeds Institute of Health Sciences, Faculty of Medicine and Health, University of Leeds, UK.

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March 2018

Using big data from health records from four countries to evaluate chronic disease outcomes: a study in 114 364 survivors of myocardial infarction.

Authors:
Eleni Rapsomaniki Marcus Thuresson Erru Yang Patrick Blin Phillip Hunt Sheng-Chia Chung Dimitris Stogiannis Mar Pujades-Rodriguez Adam Timmis Spiros C Denaxas Nicolas Danchin Michael Stokes Florence Thomas-Delecourt Cathy Emmas Pål Hasvold Em Jennings Saga Johansson David J Cohen Tomas Jernberg Nicholas Moore Magnus Janzon Harry Hemingway

Eur Heart J Qual Care Clin Outcomes 2016 Jul;2(3):172-183

Farr Institute of Health Informatics Research, University College London, London, UK.

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July 2016

Weekly variation in health-care quality by day and time of admission: a nationwide, registry-based, prospective cohort study of acute stroke care.

Authors:
Benjamin D Bray Geoffrey C Cloud Martin A James Harry Hemingway Lizz Paley Kevin Stewart Pippa J Tyrrell Charles D A Wolfe Anthony G Rudd

Lancet 2016 07 10;388(10040):170-7. Epub 2016 May 10.

Division of Health and Social Care Research, King's College London, London, UK.

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July 2016

Predicting mortality after acute coronary syndromes in people with chronic obstructive pulmonary disease.

Authors:
Kieran J Rothnie Liam Smeeth Neil Pearce Emily Herrett Adam Timmis Harry Hemingway Jadwiga Wedzicha Jennifer K Quint

Heart 2016 09 13;102(18):1442-8. Epub 2016 May 13.

Respiratory Epidemiology, Occupational Medicine and Public Health, National Heart and Lung Institute, Imperial College London, London, UK Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK.

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September 2016

Excess mortality and guideline-indicated care following non-ST-elevation myocardial infarction.

Authors:
Tatendashe B Dondo Marlous Hall Adam D Timmis Mark S Gilthorpe Oras A Alabas Phillip D Batin John E Deanfield Harry Hemingway Chris P Gale

Eur Heart J Acute Cardiovasc Care 2017 Aug 3;6(5):412-420. Epub 2016 May 3.

1 Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, UK.

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August 2017

Depression as a Risk Factor for the Initial Presentation of Twelve Cardiac, Cerebrovascular, and Peripheral Arterial Diseases: Data Linkage Study of 1.9 Million Women and Men.

Authors:
Marina Daskalopoulou Julie George Kate Walters David P Osborn G David Batty Dimitris Stogiannis Eleni Rapsomaniki Mar Pujades-Rodriguez Spiros Denaxas Ruzan Udumyan Mika Kivimaki Harry Hemingway

PLoS One 2016 22;11(4):e0153838. Epub 2016 Apr 22.

Farr Institute of Health Informatics Research, University College London, London, United Kingdom.

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March 2017

Long-term healthcare use and costs in patients with stable coronary artery disease: a population-based cohort using linked health records (CALIBER).

Authors:
Simon Walker Miqdad Asaria Andrea Manca Stephen Palmer Chris P Gale Anoop Dinesh Shah Keith R Abrams Michael Crowther Adam Timmis Harry Hemingway Mark Sculpher

Eur Heart J Qual Care Clin Outcomes 2016 Jan;2(2):125-140

Centre for Health Economics, University of York, York YO10 5DD, UK.

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January 2016

Rheumatoid Arthritis and Incidence of Twelve Initial Presentations of Cardiovascular Disease: A Population Record-Linkage Cohort Study in England.

Authors:
Mar Pujades-Rodriguez Bram Duyx Sara L Thomas Dimitris Stogiannis Anisur Rahman Liam Smeeth Harry Hemingway

PLoS One 2016 15;11(3):e0151245. Epub 2016 Mar 15.

Farr Institute of Health Informatics Research, University College London, 222 Euston Road, London NW1 2DA, United Kingdom.

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August 2016

Health and population effects of rare gene knockouts in adult humans with related parents.

Authors:
Vagheesh M Narasimhan Karen A Hunt Dan Mason Christopher L Baker Konrad J Karczewski Michael R Barnes Anthony H Barnett Chris Bates Srikanth Bellary Nicholas A Bockett Kristina Giorda Christopher J Griffiths Harry Hemingway Zhilong Jia M Ann Kelly Hajrah A Khawaja Monkol Lek Shane McCarthy Rosie McEachan Anne O'Donnell-Luria Kenneth Paigen Constantinos A Parisinos Eamonn Sheridan Laura Southgate Louise Tee Mark Thomas Yali Xue Michael Schnall-Levin Petko M Petkov Chris Tyler-Smith Eamonn R Maher Richard C Trembath Daniel G MacArthur John Wright Richard Durbin David A van Heel

Science 2016 Apr 3;352(6284):474-7. Epub 2016 Mar 3.

Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London E1 2AT, UK.

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April 2016

A 10-year prognostic model for patients with suspected angina attending a chest pain clinic.

Authors:
Neha Sekhri Pablo Perel Tim Clayton Gene S Feder Harry Hemingway Adam Timmis

Heart 2016 06 29;102(11):869-75. Epub 2016 Feb 29.

Farr Institute of Health Informatics Research at London, London, UK Department of Epidemiology and Public Health, University College London, London, UK NIHR Cardiovascular Biomedical Research Unit, Bart's Heart Centre, London, UK.

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June 2016

Using electronic health records to predict costs and outcomes in stable coronary artery disease.

Authors:
Miqdad Asaria Simon Walker Stephen Palmer Chris P Gale Anoop D Shah Keith R Abrams Michael Crowther Andrea Manca Adam Timmis Harry Hemingway Mark Sculpher

Heart 2016 05 10;102(10):755-62. Epub 2016 Feb 10.

Centre for Health Economics, University of York, York, UK.

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May 2016

Associations between polymyalgia rheumatica and giant cell arteritis and 12 cardiovascular diseases.

Authors:
Mar Pujades-Rodriguez Bram Duyx Sara L Thomas Dimitris Stogiannis Liam Smeeth Harry Hemingway

Heart 2016 Mar 19;102(5):383-9. Epub 2016 Jan 19.

Clinical Epidemiology Group, Farr Institute of Health Informatics Research, University College London, London, UK.

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March 2016

The market in healthcare data.

Authors:
Ruth Gilbert Harvey Goldstein Harry Hemingway

BMJ 2015 Nov 4;351:h5897. Epub 2015 Nov 4.

Farr Institute of Health Informatics Research, University College London, UK.

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November 2015

Authors' reply to Gupta.

Authors:
Sheng-Chia Chung Johan Sundström Chris P Gale Adam Timmis Tomas Jernberg Harry Hemingway

BMJ 2015 Sep 30;351:h5140. Epub 2015 Sep 30.

Farr Institute of Health Informatics Research and Institute of Health Informatics, University College London, London NW1 2DA, UK.

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September 2015

Changes in health in England, with analysis by English regions and areas of deprivation, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.

Authors:
John N Newton Adam D M Briggs Christopher J L Murray Daniel Dicker Kyle J Foreman Haidong Wang Mohsen Naghavi Mohammad H Forouzanfar Summer Lockett Ohno Ryan M Barber Theo Vos Jeffrey D Stanaway Jürgen C Schmidt Andrew J Hughes Derek F J Fay Russell Ecob Charis Gresser Martin McKee Harry Rutter Ibrahim Abubakar Raghib Ali H Ross Anderson Amitava Banerjee Derrick A Bennett Eduardo Bernabé Kamaldeep S Bhui Stanley M Biryukov Rupert R Bourne Carol E G Brayne Nigel G Bruce Traolach S Brugha Michael Burch Simon Capewell Daniel Casey Rajiv Chowdhury Matthew M Coates Cyrus Cooper Julia A Critchley Paul I Dargan Mukesh K Dherani Paul Elliott Majid Ezzati Kevin A Fenton Maya S Fraser Thomas Fürst Felix Greaves Mark A Green David J Gunnell Bernadette M Hannigan Roderick J Hay Simon I Hay Harry Hemingway Heidi J Larson Katharine J Looker Raimundas Lunevicius Ronan A Lyons Wagner Marcenes Amanda J Mason-Jones Fiona E Matthews Henrik Moller Michele E Murdoch Charles R Newton Neil Pearce Frédéric B Piel Daniel Pope Kazem Rahimi Alina Rodriguez Peter Scarborough Austin E Schumacher Ivy Shiue Liam Smeeth Alison Tedstone Jonathan Valabhji Hywel C Williams Charles D A Wolfe Anthony D Woolf Adrian C J Davis

Lancet 2015 Dec 14;386(10010):2257-74. Epub 2015 Sep 14.

Public Health England, London, UK; London School of Economics, London, UK; University College London, London, UK.

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December 2015

How Does Cardiovascular Disease First Present in Women and Men? Incidence of 12 Cardiovascular Diseases in a Contemporary Cohort of 1,937,360 People.

Authors:
Julie George Eleni Rapsomaniki Mar Pujades-Rodriguez Anoop Dinesh Shah Spiros Denaxas Emily Herrett Liam Smeeth Adam Timmis Harry Hemingway

Circulation 2015 Oct 1;132(14):1320-8. Epub 2015 Sep 1.

From Farr Institute of Health Informatics Research (London), University College London, United Kingdom (J.G., M.P.-R., A.D.S., S.D., H.H.); Worldwide Clinical Trials, Nottingham, United Kingdom (E.R.); Farr Institute of Health Informatics Research (London), London School of Hygiene & Tropical Medicine, United Kingdom (E.H., L.S.); and Farr Institute of Health Informatics Research (London) and Barts National Institute for Health Research Cardiovascular Biomedical Research Unit, Queen Mary University of London, United Kingdom (A.T.).

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October 2015

Type 2 diabetes and incidence of a wide range of cardiovascular diseases: a cohort study in 1·9 million people.

Authors:
Anoop Dinesh Shah Claudia Langenberg Eleni Rapsomaniki Spiros Denaxas Mar Pujades-Rodriguez Chris P Gale John Deanfield Liam Smeeth Adam Timmis Harry Hemingway

Lancet 2015 Feb;385 Suppl 1:S86

Farr Institute of Health Informatics Research, University College London, London, UK.

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February 2015

Feasibility and impact of a computerised clinical decision support system on investigation and initial management of new onset chest pain: a mixed methods study.

Authors:
Rachel Johnson Maggie Evans Helen Cramer Kristina Bennert Richard Morris Sandra Eldridge Katy Juttner Mohammed J Zaman Harry Hemingway Spiros Denaxas Adam Timmis Gene Feder

BMC Med Inform Decis Mak 2015 Aug 26;15:71. Epub 2015 Aug 26.

Centre for Academic Primary Care, School of Social and Community Medicine, University of Bristol, Bristol, UK.

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August 2015

Comparison of hospital variation in acute myocardial infarction care and outcome between Sweden and United Kingdom: population based cohort study using nationwide clinical registries.

Authors:
Sheng-Chia Chung Johan Sundström Chris P Gale Stefan James John Deanfield Lars Wallentin Adam Timmis Tomas Jernberg Harry Hemingway

BMJ 2015 Aug 7;351:h3913. Epub 2015 Aug 7.

Farr Institute of Health Informatics Research and Institute of Health Informatics, University College London, London NW1 2DA, UK.

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August 2015

Atypical chest pain in diabetic patients with suspected stable angina: impact on diagnosis and coronary outcomes.

Authors:
Cornelia Junghans Neha Sekhri M Justin Zaman Harry Hemingway Gene S Feder Adam Timmis

Eur Heart J Qual Care Clin Outcomes 2015 Jul;1(1):37-43

Dept Cardiology, Barts Heart Centre, Queen Mary University London, West Smithfield, London EC1A 7BE, UK.

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July 2015

Use of electronic health records to ascertain, validate and phenotype acute myocardial infarction: A systematic review and recommendations.

Authors:
Bruna Rubbo Natalie K Fitzpatrick Spiros Denaxas Marina Daskalopoulou Ning Yu Riyaz S Patel Harry Hemingway

Int J Cardiol 2015 5;187:705-11. Epub 2015 Mar 5.

Farr Institute of Health Informatics Research, University College London, UK.

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February 2016

Closing the mortality gap after a myocardial infarction in people with and without chronic obstructive pulmonary disease.

Authors:
Kieran J Rothnie Liam Smeeth Emily Herrett Neil Pearce Harry Hemingway Jadwiga Wedzicha Adam Timmis Jennifer K Quint

Heart 2015 Jul 12;101(14):1103-10. Epub 2015 Mar 12.

Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK.

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July 2015

The science of clinical practice: disease diagnosis or patient prognosis? Evidence about "what is likely to happen" should shape clinical practice.

Authors:
Peter Croft Douglas G Altman Jonathan J Deeks Kate M Dunn Alastair D Hay Harry Hemingway Linda LeResche George Peat Pablo Perel Steffen E Petersen Richard D Riley Ian Roberts Michael Sharpe Richard J Stevens Danielle A Van Der Windt Michael Von Korff Adam Timmis

BMC Med 2015 Jan 30;13:20. Epub 2015 Jan 30.

Arthritis Research UK Primary Care Centre, Research Institute for Primary Care and Health Sciences, Keele University, Keele ST5 5BG, Staffordshire, UK.

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January 2015

Type 2 diabetes and incidence of cardiovascular diseases: a cohort study in 1·9 million people.

Authors:
Anoop Dinesh Shah Claudia Langenberg Eleni Rapsomaniki Spiros Denaxas Mar Pujades-Rodriguez Chris P Gale John Deanfield Liam Smeeth Adam Timmis Harry Hemingway

Lancet Diabetes Endocrinol 2015 Feb 11;3(2):105-13. Epub 2014 Nov 11.

Farr Institute of Health Informatics Research at London, London, UK; Department of Epidemiology and Public Health, University College London, London, UK.

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February 2015

Survival in acute myocardial infarction - Authors' reply.

Authors:
Sheng-Chia Chung Adam Timmis Tomas Jernberg Harry Hemingway

Lancet 2014 Nov 31;384(9954):1574-5. Epub 2014 Oct 31.

The Farr Institute of Health Informatics Research, Department of Epidemiology & Public Health, University College London, 222 Euston Road, London NW1 2DA, UK.

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November 2014

Heterogeneous associations between smoking and a wide range of initial presentations of cardiovascular disease in 1937360 people in England: lifetime risks and implications for risk prediction.

Authors:
Mar Pujades-Rodriguez Julie George Anoop Dinesh Shah Eleni Rapsomaniki Spiros Denaxas Robert West Liam Smeeth Adam Timmis Harry Hemingway

Int J Epidemiol 2015 Feb 20;44(1):129-41. Epub 2014 Nov 20.

Farr Institute of Health Informatics Research, University College London, London, UK, Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK and National Institute for Health Research, Biomedical Research Unit, Barts Health NHS Trust, London, UK.

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February 2015

Defining disease phenotypes using national linked electronic health records: a case study of atrial fibrillation.

Authors:
Katherine I Morley Joshua Wallace Spiros C Denaxas Ross J Hunter Riyaz S Patel Pablo Perel Anoop D Shah Adam D Timmis Richard J Schilling Harry Hemingway

PLoS One 2014 4;9(11):e110900. Epub 2014 Nov 4.

Farr Institute of Health Informatics Research, University College London, London, United Kingdom, and Clinical Epidemiology, Department of Epidemiology and Public Health, University College London, London, United Kingdom.

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July 2015