Publications by authors named "Harriet Druker"

25Publications

Second rhabdoid tumor 8 years after treatment of atypical teratoid/rhabdoid tumor in a child with germline SMARCB1 mutation.

Pediatr Blood Cancer 2019 03 4;66(3):e27546. Epub 2018 Nov 4.

Pediatric Brain Tumour Program, The Hospital for Sick Children, University of Toronto, Ontario, Canada.

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http://doi.wiley.com/10.1002/pbc.27546
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http://dx.doi.org/10.1002/pbc.27546DOI Listing
March 2019

"A change in perspective": Exploring the experiences of adolescents with hereditary tumor predisposition.

Pediatr Blood Cancer 2019 01 11;66(1):e27445. Epub 2018 Sep 11.

Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/pbc.27445DOI Listing
January 2019

Evidence for genetic anticipation in vonHippel-Lindau syndrome.

J Med Genet 2018 06 7;55(6):395-402. Epub 2018 Feb 7.

Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, Canada.

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http://dx.doi.org/10.1136/jmedgenet-2017-104882DOI Listing
June 2018

DICER1 syndrome: Approach to testing and management at a large pediatric tertiary care center.

Pediatr Blood Cancer 2018 Jan 27;65(1). Epub 2017 Sep 27.

Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/pbc.26720DOI Listing
January 2018

Genetic Counselor Recommendations for Cancer Predisposition Evaluation and Surveillance in the Pediatric Oncology Patient.

Clin Cancer Res 2017 07;23(13):e91-e97

Section of Hematology, Oncology, and Bone Marrow Transplantation, University of Colorado Anschutz Medical Campus, Children's Hospital Colorado, Aurora, Colorado.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-0834DOI Listing
July 2017

Cancer and Central Nervous System Tumor Surveillance in Pediatric Neurofibromatosis 2 and Related Disorders.

Clin Cancer Res 2017 Jun;23(12):e54-e61

Division of Haematology/Oncology, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-0590DOI Listing
June 2017

Pediatric imaging in DICER1 syndrome.

Pediatr Radiol 2017 Sep 4;47(10):1292-1301. Epub 2017 May 4.

Department of Diagnostic Imaging, The Hospital for Sick Children, 555 University Ave., Toronto, Ontario, M5G 1X8, Canada.

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http://dx.doi.org/10.1007/s00247-017-3875-0DOI Listing
September 2017

Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors.

Authors:
Jonathon Torchia Brian Golbourn Shengrui Feng King Ching Ho Patrick Sin-Chan Alexandre Vasiljevic Joseph D Norman Paul Guilhamon Livia Garzia Natalia R Agamez Mei Lu Tiffany S Chan Daniel Picard Pasqualino de Antonellis Dong-Anh Khuong-Quang Aline C Planello Constanze Zeller Dalia Barsyte-Lovejoy Lucie Lafay-Cousin Louis Letourneau Mathieu Bourgey Man Yu Deena M A Gendoo Misko Dzamba Mark Barszczyk Tiago Medina Alexandra N Riemenschneider A Sorana Morrissy Young-Shin Ra Vijay Ramaswamy Marc Remke Christopher P Dunham Stephen Yip Ho-Keung Ng Jian-Qiang Lu Vivek Mehta Steffen Albrecht Jose Pimentel Jennifer A Chan Gino R Somers Claudia C Faria Lucia Roque Maryam Fouladi Lindsey M Hoffman Andrew S Moore Yin Wang Seung Ah Choi Jordan R Hansford Daniel Catchpoole Diane K Birks Nicholas K Foreman Doug Strother Almos Klekner Laszló Bognár Miklós Garami Péter Hauser Tibor Hortobágyi Beverly Wilson Juliette Hukin Anne-Sophie Carret Timothy E Van Meter Eugene I Hwang Amar Gajjar Shih-Hwa Chiou Hideo Nakamura Helen Toledano Iris Fried Daniel Fults Takafumi Wataya Chris Fryer David D Eisenstat Katrin Scheinemann Adam J Fleming Donna L Johnston Jean Michaud Shayna Zelcer Robert Hammond Samina Afzal David A Ramsay Nongnuch Sirachainan Suradej Hongeng Noppadol Larbcharoensub Richard G Grundy Rishi R Lulla Jason R Fangusaro Harriet Druker Ute Bartels Ronald Grant David Malkin C Jane McGlade Theodore Nicolaides Tarik Tihan Joanna Phillips Jacek Majewski Alexandre Montpetit Guillaume Bourque Gary D Bader Alyssa T Reddy G Yancey Gillespie Monika Warmuth-Metz Stefan Rutkowski Uri Tabori Mathieu Lupien Michael Brudno Ulrich Schüller Torsten Pietsch Alexander R Judkins Cynthia E Hawkins Eric Bouffet Seung-Ki Kim Peter B Dirks Michael D Taylor Anat Erdreich-Epstein Cheryl H Arrowsmith Daniel D De Carvalho James T Rutka Nada Jabado Annie Huang

Cancer Cell 2016 Dec;30(6):891-908

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5G0A4, Canada; Department of Paediatrics, University of Toronto, Toronto, ON M5G0A4, Canada; Division of Hematology/Oncology, Hospital for Sick Children, Toronto, ON M5G1X8, Canada; Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children, Toronto, ON M5G1X8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500911PMC
December 2016

Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: 11 year follow-up of a prospective observational study.

Lancet Oncol 2016 Sep 5;17(9):1295-305. Epub 2016 Aug 5.

Department of Pediatrics, University of Toronto, Toronto, ON, Canada; Division of Hematology/Oncology, University of Toronto, Toronto, ON, Canada; Genetics & Genomic Biology Program, University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(16)30249-2DOI Listing
September 2016

Somatic DICER1 mutations in adult-onset pulmonary blastoma.

Eur Respir J 2016 06 28;47(6):1879-82. Epub 2016 Apr 28.

Dept of Human Genetics, McGill University, Montreal, QC, Canada Lady Davis Institute, Segal Cancer Centre, Jewish General Hospital, Montreal, QC, Canada Dept of Medical Genetics, Research Institute of the McGill University Health Centre, Montreal, QC, Canada Program in Cancer Genetics, Department of Oncology and Human Genetics, McGill University, Montreal, QC, Canada

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http://dx.doi.org/10.1183/13993003.00172-2016DOI Listing
June 2016

Evolution of Renal Cysts to Anaplastic Sarcoma of Kidney in a Child With DICER1 Syndrome.

Pediatr Blood Cancer 2016 07 29;63(7):1272-5. Epub 2016 Feb 29.

Department of Medical Genetics, Lady Davis Institute, Jewish General Hospital, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1002/pbc.25959DOI Listing
July 2016

Ovarian embryonal rhabdomyosarcoma is a rare manifestation of the DICER1 syndrome.

Hum Pathol 2015 Jun 5;46(6):917-22. Epub 2015 Mar 5.

Department of Human Genetics, McGill University, Montreal, Quebec, Canada H3A 0G4; Lady Davis Institute, Segal Cancer Centre, Jewish General Hospital, Montreal, Quebec, Canada H3T 1E2; Department of Medical Genetics, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada H3H 2R9; Program in Cancer Genetics, Department of Oncology and Human Genetics, McGill University, Montreal, Quebec, Canada H2W 1S6. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2015.02.008DOI Listing
June 2015

Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers.

Nat Genet 2015 Mar 2;47(3):257-62. Epub 2015 Feb 2.

1] Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada. [2] The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada. [3] Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada. [4] Department of Pediatrics, University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/ng.3202DOI Listing
March 2015

Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: a prospective observational study.

Lancet Oncol 2011 Jun 19;12(6):559-67. Epub 2011 May 19.

Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/S1470-2045(11)70119-XDOI Listing
June 2011

Excessive genomic DNA copy number variation in the Li-Fraumeni cancer predisposition syndrome.

Proc Natl Acad Sci U S A 2008 Aug 6;105(32):11264-9. Epub 2008 Aug 6.

Program in Genetics and Genome Biology, Departments of Medical Biophysics, Centre for Applied Genomics, and Division of Hematology/Oncology, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1073/pnas.0802970105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516272PMC
August 2008

Younger age of cancer initiation is associated with shorter telomere length in Li-Fraumeni syndrome.

Cancer Res 2007 Feb;67(4):1415-8

Division of Hematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, 555 University Avenue, Toronto, Canada.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-3682DOI Listing
February 2007

Unusual ocular presentation of von Hippel-Lindau disease.

Can J Ophthalmol 2005 Oct;40(5):593-7

Department of Ophthalmology and Visual Sciences, The Hospital for Sick Children, Toronto, Ont.

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http://dx.doi.org/10.1016/S0008-4182(05)80051-1DOI Listing
October 2005