Publications by authors named "Harri Sihto"

49Publications

Clinical relevance of integrin alpha 4 in gastrointestinal stromal tumours.

J Cell Mol Med 2018 04 29;22(4):2220-2230. Epub 2018 Jan 29.

Laboratory of Molecular Oncology, Translational Cancer Biology Program, Department of Oncology, University of Helsinki, Helsinki, Finland.

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April 2018

SLUG transcription factor: a pro-survival and prognostic factor in gastrointestinal stromal tumour.

Br J Cancer 2017 Apr 23;116(9):1195-1202. Epub 2017 Mar 23.

Laboratory of Molecular Oncology, Translational Cancer Biology Research Program, Department of Oncology, University of Helsinki, P.O Box 63, FI-00014 University of Helsinki, Helsinki, Finland.

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April 2017

Motility of glioblastoma cells is driven by netrin-1 induced gain of stemness.

J Exp Clin Cancer Res 2017 01 9;36(1). Epub 2017 Jan 9.

Translational Cancer Biology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.

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January 2017

History of chronic inflammatory disorders increases the risk of Merkel cell carcinoma, but does not correlate with Merkel cell polyomavirus infection.

Br J Cancer 2017 Jan 15;116(2):260-264. Epub 2016 Dec 15.

Finnish Cancer Registry, Institute for Statistical and Epidemiological Cancer Research, Helsinki, Finland.

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January 2017

Adjuvant Imatinib for High-Risk GI Stromal Tumor: Analysis of a Randomized Trial.

J Clin Oncol 2016 Jan 2;34(3):244-50. Epub 2015 Nov 2.

Heikki Joensuu and Petri Bono, Comprehensive Cancer Center Helsinki; Heikki Joensuu, Harri Sihto, and Petri Bono, University of Helsinki, Helsinki; Raija Kallio, Oulu University Hospital, Oulu; Jouni Junnila, 4Pharma, Turku, Finland; Mikael Eriksson and Thor Alvegård, Lund University, Lund; Bengt Nilsson, Sahlgrenska University Hospital, Gothenburg, Sweden; Kirsten Sundby Hall, Oslo University Hospital, Oslo, Norway; Annette Reichardt, Daniel Pink, and Peter Reichardt, Sarkomzentrum Berlin-Brandenburg, HELIOS Klinikum Berlin-Buch, Berlin; Jörg T. Hartmann, Franziskus Hospital, Catholic Hospital Consortium Ostwestfalen, Bielefeld; Giuliano Ramadori, University of Göttingen, Göttingen; Peter Hohenberger, Mannheim University Medical Center, Mannheim; Salah-Eddin Al-Batran, Klinik für Onkologie und Hämatologie am Krankenhaus Nordwest, Frankfurt; Marcus Schlemmer, University Hospital Großhadern, Ludwig Maximilians University, Munich; Sebastian Bauer, Sarcoma Center, West German Cancer Center, Essen; and Eva Wardelmann, Gerhard-Domagk-Institute of Pathology, University Hospital Münster, Münster, Germany.

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January 2016

Elevated levels of StAR-related lipid transfer protein 3 alter cholesterol balance and adhesiveness of breast cancer cells: potential mechanisms contributing to progression of HER2-positive breast cancers.

Am J Pathol 2015 Apr 12;185(4):987-1000. Epub 2015 Feb 12.

Faculty of Medicine, Department of Anatomy, University of Helsinki, Helsinki, Finland; Minerva Foundation Institute for Medical Research, Biomedicum 2U, Helsinki, Finland. Electronic address:

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April 2015

RB1 gene in Merkel cell carcinoma: hypermethylation in all tumors and concurrent heterozygous deletions in the polyomavirus-negative subgroup.

APMIS 2014 Dec 16;122(12):1157-66. Epub 2014 Apr 16.

Department of Pathology, Helsinki University and HUSLAB, Helsinki, Finland; Department of Plastic Surgery, Helsinki University Hospital, Helsinki, Finland.

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December 2014

Novel target for peptide-based imaging and treatment of brain tumors.

Mol Cancer Ther 2014 Apr 3;13(4):996-1007. Epub 2014 Feb 3.

Authors' Affiliations: Research Programs Unit, Translational Cancer Biology and Institute of Biomedicine and Laboratory of Molecular Oncology, Biomedicum Helsinki, University of Helsinki; Department of Oncology, Helsinki University Central Hospital; Finnish Cancer Institute, Helsinki; A.I. Virtanen Institute for Molecular Medicine, University of Eastern Finland, Kuopio, Finland; Department of Neurochemistry, Stockholm University, Stockholm, Sweden; and UCSF Helen Diller Family Cancer Center, San Francisco, California.

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April 2014

Tumor-infiltrating lymphocytes and outcome in Merkel cell carcinoma, a virus-associated cancer.

Oncoimmunology 2012 Nov;1(8):1420-1421

Laboratory of Molecular Oncology and Molecular Cancer Biology Program; University of Helsinki; Helsinki, Finland.

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November 2012

Bcl-2 expression indicates better prognosis of Merkel cell carcinoma regardless of the presence of Merkel cell polyomavirus.

Virchows Arch 2012 Nov 14;461(5):553-9. Epub 2012 Sep 14.

Department of Plastic and Reconstructive Surgery, Helsinki University Hospital, Helsinki, Finland.

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November 2012

Tumor infiltrating immune cells and outcome of Merkel cell carcinoma: a population-based study.

Clin Cancer Res 2012 May 30;18(10):2872-81. Epub 2012 Mar 30.

Laboratory of Molecular Oncology and Molecular Cancer Biology Program, University of Helsinki, Helsinki, Finland.

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May 2012

Long-term prognosis of breast cancer detected by mammography screening or other methods.

Breast Cancer Res 2011 28;13(6):R134. Epub 2011 Dec 28.

Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Biomedicum Helsinki 2U, Tukholmankatu 8, PO Box 20, FI-00014 Helsinki, Finland.

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June 2012

An extensive tumor array analysis supports tumor suppressive role for nucleophosmin in breast cancer.

Am J Pathol 2011 Aug 2;179(2):1004-14. Epub 2011 Jun 2.

Research Programs Unit, Molecular Cancer Biology, and Institute of Biomedicine, University of Helsinki, Helsinki, Finland.

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August 2011

Merkel cell polyomavirus infection, large T antigen, retinoblastoma protein and outcome in Merkel cell carcinoma.

Clin Cancer Res 2011 Jul 3;17(14):4806-13. Epub 2011 Jun 3.

Laboratory of Molecular Oncology, Biomedicum Helsinki, Finland.

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July 2011

Incidence of Merkel cell carcinoma in renal transplant recipients.

Nephrol Dial Transplant 2009 Oct 8;24(10):3231-5. Epub 2009 Jul 8.

Department of Plastic Surgery, Helsinki University Hospital, Helsinki, Finland.

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October 2009

Clinical factors associated with Merkel cell polyomavirus infection in Merkel cell carcinoma.

J Natl Cancer Inst 2009 Jul 17;101(13):938-45. Epub 2009 Jun 17.

Laboratory of Molecular Oncology, Biomedicum, Helsinki, Finland.

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July 2009

Amplification of KIT, PDGFRA, VEGFR2, and EGFR in gliomas.

Mol Cancer Res 2006 Dec;4(12):927-34

Laboratory of Molecular Oncology, Biomedicum Helsinki, Helsinki, Finland.

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December 2006

Platelet-derived growth factor receptor family mutations in gastrointestinal stromal tumours.

Scand J Gastroenterol 2006 Jul;41(7):805-11

Laboratory of Molecular Oncology, Biomedicum, Haartmaninkatu 8, PO Box 700, FIN-00029 Helsinki, Finland.

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July 2006

Gastrointestinal stromal tumors with KIT exon 11 deletions are associated with poor prognosis.

Gastroenterology 2006 May;130(6):1573-81

Department of Pathology at the Sahlgrenska Academy, Lundberg Laboratory for Cancer Research, Göteborg University, Göteborg, Sweden.

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May 2006

Allelic imbalance of HER2 variant in sporadic breast and ovarian cancer.

Cancer Genet Cytogenet 2006 May;167(1):32-8

Laboratory of Molecular Oncology, Department of Oncology, Helsinki University Central Hospital, Biomedicum Helsinki, P.O. Box 700, FIN-00029 Helsinki, Finland.

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May 2006

Gene amplification, mutation, and protein expression of EGFR and mutations of ERBB2 in serous ovarian carcinoma.

J Mol Med (Berl) 2006 Aug 11;84(8):671-81. Epub 2006 Apr 11.

Department of Obstetrics and Gynecology, Helsinki University Central Hospital, P.O. Box 700, (Haartmanink. 8), FIN-00029 HUS, Helsinki, Finland.

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August 2006

Epidermal growth factor receptor domain II, IV, and kinase domain mutations in human solid tumors.

J Mol Med (Berl) 2005 Dec 31;83(12):976-83. Epub 2005 Aug 31.

Laboratory of Molecular Oncology, Room B426B, 4th floor, Biomedicum, Haartmaninkatu 8, P.O. Box 700, 00029 Helsinki, Finland.

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December 2005

NF1-associated gastrointestinal stromal tumors have unique clinical, phenotypic, and genotypic characteristics.

Am J Surg Pathol 2005 Sep;29(9):1170-6

Lundberg Laboratory for Cancer Research, Department of Pathology, Sahlgrenska Academy, Göteborg University, Göteborg, Sweden.

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September 2005

KIT and platelet-derived growth factor receptor alpha tyrosine kinase gene mutations and KIT amplifications in human solid tumors.

J Clin Oncol 2005 Jan 15;23(1):49-57. Epub 2004 Nov 15.

Department of Oncology, Helsinki University Central Hospital, Haartmaninkatu 4, PO Box 180, FIN-00029 Helsinki, Finland.

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January 2005