Publications by authors named "Haroldo Vieira de Moraes"

13 Publications

  • Page 1 of 1

Severe Necrotising Toxoplasmic Retinochoroiditis in a Patient With Crohn's Disease in Use of Adalimumab and Azathioprine.

Inflamm Bowel Dis 2020 06;26(7):e69-e70

Department of Internal Medicine, Gastroenterology Division, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1093/ibd/izaa105DOI Listing
June 2020

The optimal time to perform an ophthalmic examination of patients with inflammatory bowel disease.

Intest Res 2019 Jan 14;17(1):153-154. Epub 2018 Dec 14.

Division of Gastroenterology, Department of Internal Medicine, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.

View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.5217/ir.2018.00147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361020PMC
January 2019

Anterior and Intermediate Uveitis Following Yellow Fever Vaccination with Fractional Dose: Case Reports.

Ocul Immunol Inflamm 2019 28;27(4):521-523. Epub 2018 Aug 28.

a Ophthalmology Department , Universidade Federal do Rio de Janeiro , Rio de Janeiro , Brazil.

: To describe two cases of anterior and intermediate uveitis following yellow fever vaccination with fractional dose. : Case report. : Case 1: A 35 year-old healthy woman presented with unilateral anterior uveitis 10 days after the yellow fever vaccination. Testing excluded infectious and rheumatic diseases and the episode was fully recovered after a short course of topical treatment. Case 2: A 21 year-old previously healthy woman presented with blurred vision in the left eye (OS) 14 days after the yellow fever vaccination. The ophthalmic examination of the OS revealed intermediated uveitis. Testing excluded infectious and neurological diseases. After six weeks of treatment with oral prednisone, the ocular inflammation had resolved. : Physicians should be aware of the possibility of eye inflammation following the yellow fever vaccination.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1080/09273948.2018.1510529DOI Listing
December 2019

The Role of Clinical-Demographic Characteristics in Ophthalmic Manifestations of Inflammatory Bowel Disease.

Inflamm Bowel Dis 2019 02;25(3):e15-e16

Department of Ophthalmology, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.

View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1093/ibd/izy159DOI Listing
February 2019

Ophthalmic manifestations in patients with inflammatory bowel disease: A review.

World J Gastroenterol 2017 Aug;23(32):5836-5848

Department of Internal Medicine, Gastroenterology Division, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-913, Brazil.

Clinical manifestations of inflammatory bowel disease (IBD) are not locally restricted to the gastrointestinal tract, and a significant portion of patients have involvement of other organs and systems. The visual system is one of the most frequently affected, mainly by inflammatory disorders such as episcleritis, uveitis and scleritis. A critical review of available literature concerning ocular involvement in IBD, as it appears in PubMed, was performed. Episcleritis, the most common ocular extraintestinal manifestation (EIM), seems to be more associated with IBD activity when compared with other ocular EIMs. In IBD patients, anterior uveitis has an insidious onset, it is longstanding and bilateral, and not related to the intestinal disease activity. Systemic steroids or immunosuppressants may be necessary in severe ocular inflammation cases, and control of the underlying bowel disease is important to prevent recurrence. Our review revealed that ocular involvement is more prevalent in Crohn's disease than ulcerative colitis, in active IBD, mainly in the presence of other EIMs. The ophthalmic symptoms in IBD are mainly non-specific and their relevance may not be recognized by the clinician; most ophthalmic manifestations are treatable, and resolve without sequel upon prompt treatment. A collaborative clinical care team for management of IBD that includes ophthalmologists is central for improvement of quality care for these patients, and it is also cost-effective.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.3748/wjg.v23.i32.5836DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583569PMC
August 2017

Refractive and Quality of Vision Outcomes with Toric IOL Implantation in Low Astigmatism.

J Ophthalmol 2016 14;2016:5424713. Epub 2016 Dec 14.

Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.

To evaluate the refractive and the quality of vision outcomes of toric IOL implantation in patients with low astigmatism. Prospective study of single-arm. Patients with corneal astigmatism range from 0,75 D to 1,5 D and cataract that underwent cataract surgery with toric IOL. The measurements were performed preoperatively and 6 weeks after the surgery. Patients were evaluated for visual acuity with and without correction, contrast sensitivity, static and dynamic refraction, and quality of life questionnaire. Pre- and postoperative values were compared and their variations were evaluated for linear correlation. 21 eyes of 21 patients. Postoperative mean uncorrected visual acuity was 0.80 ± 0.19, and the best corrected visual acuity was 0.97 ± 0.15. < 0.001 compared to preoperative values. The average postoperative refractive cylinder was -0.34 ± 0.39. The questionnaire's total value before and after surgery was, respectively, 43.20 ± 15.76 and 79.70 ± 10.11 ( < 0.001). The correlation coefficients between the values of the questionnaire variation and the UCVA, BCVA, and CS variation were, respectively, 0.548 ( = 0.005), 0.508 ( = 0.009), and 0.409 ( = 0.033). Patients with low astigmatism who underwent phacoemulsification with toric IOL implantation experienced significant decrease in refractive astigmatism and improvement in their quality of life.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1155/2016/5424713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192334PMC
December 2016

[Retinal central vein occlusion in remission of Crohn's disease: case report].

Arq Bras Oftalmol 2007 Nov-Dec;70(6):1034-6

Serviço de Oftalmologia, Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.

Inflammatory bowel disease (IBD) includes Crohn's disease and ulcerative colitis. Both diseases are characterized by chronic inflammation of the intestines. The advances in understanding the inflammatory process improved the treatment of inflammatory bowel disease. The systemic complications of inflammatory bowel disease involve several organs included the eyes. The incidence of eye complications in IBD is unknown, but according to the literature the incidence vary between 3.5% and 11.8%. The ophthalmic complications are usually of inflammatory origin. We report a case of a patient with Crohn's disease that developed central retinal vein occlusion and papillophlebitis without any other retinal vascular disease during remission. The aim of this paper is to reinforce the importance of complete ophthalmic examination perform as a routine in patients with inflammatory bowel disease.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1590/s0004-27492007000600029DOI Listing
August 2008

Thrombophilic mutations and risk of retinal vein occlusion.

Arq Bras Oftalmol 2007 Nov-Dec;70(6):971-4

Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.

Purpose: The association of retinal vein occlusion and hereditary thrombophilia abnormalities is not established, with controversial results in the literature. This study investigates the association between retinal vein occlusion and three thrombophilic mutations: factor V 1691A (factor V Leiden), prothrombin 20210A (PT 20210A) and homozygous methylenetetrahydrofolate reductase 677T (MTHFR 677TT).

Methods: 55 consecutive retinal vein occlusion patients and 55 controls matched by age, gender and race, were tested for the presence of the following mutations: factor V Leiden, PT 20210A and MTHFR 677TT. The frequencies of the three mutations in cases and controls were compared.

Results: Factor V Leiden was found in 3.6% of patients and in 0% of controls; PT 20210A was found in 1.8% of patients and 3.6% of controls, (matched-pair odds ratio, 0.5; 95% confidence interval, 0.04 to 5.51); MTHFR 677TT was found in 9% of patients and 9% of controls (matched-pair odds ratio, 1; 95% confidence interval, 0.92 to 3.45). Arterial hypertension was more frequent in patients than controls (matched-pair odds ratio, 3.4; 95% confidence interval, 1.25 to 9.21).

Conclusions: This study suggests that thrombophilic mutations are not risk factors for RVO. Routine investigation of hereditary thrombophilia in these patients is not justified.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1590/s0004-27492007000600016DOI Listing
August 2008

[The relationship between the length of ciliary processes as measured by ultrasound biomicroscopy and the duration, localization and severity of uveitis].

Arq Bras Oftalmol 2006 May-Jun;69(3):383-8

Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.

Purpose: To determine the relationship between the length of ciliary processes as measured by ultrasound biomicroscopy and the duration, localization and severity of uveitis.

Methods: We analyzed in this prospective study, 58 individuals including patients with different stages of uveitis and normal patients (112 eyes including 18 normal), between August 2001 and August 2002, at the Cleveland Clinic Foundation, Ohio, USA. All patients were referred to ultrasound biomicroscopy by the Uveitis Department, after a complete ophthalmological examination. A 50 MHz-transducer UBM model 840 (Zeiss-Humphrey) was used under topical anesthesia and immersion technique.

Results: The most frequent etiology was idiophatic uveitis (27.8%). Recurrent, aggressive and diffuse uveitis lead to significant damage of the ciliary processes. The most significant loss of the ciliary processes was found in the inferior quadrant and the highest in normal patients and in the temporal quadrant. Hypotonic eyes have their ciliary processes reduced.

Conclusions: Ultrasound biomicroscopy has proved to be useful in evaluating anatomical changes of ciliary processes in uveitis and in ocular hypotony, and provides a basis to, make recommendations regarding baseline screening of uveitis patients. Patients who are found to have atrophy of the ciliary processes may need a more aggressive treatment for any signs of inflammation to prevent further damage and eventual hypotony.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1590/s0004-27492006000300018DOI Listing
April 2007

[Fundus changes evaluation in degenerative myopia].

Arq Bras Oftalmol 2006 Mar-Apr;69(2):203-6. Epub 2006 May 8.

Departamento de Oftalmologia, Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro (RJ), Brazil.

Purpose: To evaluate the presence of fundus changes in degenerative myopia.

Methods: Forty patients with refractive error of at least -6.00 diopters were selected for ophthalmologic examination followed by posterior pole photograph and echobiometry.

Results: We studied 57 eyes of 37 patients with refractive error ranging from -6.25 to -28.50 diopters, with mean -14.05, and axial length ranging from 26.06 to 32.86 mm, with mean 28.01. We found a temporal crescent in 36.5% and a peripapillary one in 20% of the eyes. Choroidal vessels were seen in 35% of the eyes. Posterior pole changes were as follow: posterior staphyloma in 10.5%, Fuchs' spots in 3.5% and lacquer cracks in 1.5%. Peripheral retinal examination revealed paving stone chorioretinal atrophy in 17.5%, white without pressure in 10.5%, lattice degeneration in 5%, retinal tears in 3.5% and retinoschisis in 1.5% of the examined eyes.

Conclusions: Fundus changes that lead to decreased vision are common in patients with degenerative myopia. Peripheral retinal examination is very important in these patients due to the increased risk of retinal detachment.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1590/s0004-27492006000200013DOI Listing
October 2006

[Congenital retinal macrovessel: case report].

Arq Bras Oftalmol 2005 May-Jun;68(3):405-6. Epub 2005 Jul 26.

Departamento de Oftalmologia, Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.

Congenital retinal macrovessel is a rare vascular anomaly in which a large vessel and its tributaries cross the macula. We describe a case of retinal macrovessel in a patient complaining of decrease in visual acuity.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1590/S0004-27492005000300026DOI Listing
March 2006

[Number, shape, and topography of leakage points in patients with central serous chorioretinopathy].

Arq Bras Oftalmol 2005 May-Jun;68(3):317-20. Epub 2005 Jul 26.

Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.

Purpose: To evaluate the number, shape and topography of leakage points in patients with central serous chorioretinopathy (CSC).

Methods: Digital photographic files of fluorescein angiography with the diagnosis of CSC were reviewed by the author. The cases considered in remission and the examinations related to the same episode were excluded. The author filled out a form containing medical record number, initials, sex, age, date of the examination and leakage point characteristics (number, shape, and topography) of the selected cases.

Results: The examinations of 418 patients (455 eyes) were included, with a male:female ratio of 2.32:1. Ninety-one point fifteen percent of the patients presented the disease unilaterally and 8.85% bilaterally. The mean age was 43.04 years (range, 19-68 years). Among the 455 selected eyes, 88.35% presented typical forms of CSC while 10.11% decompensation of the retinal pigment epithelium and 1.54% with isolated retinal pigment epithelium (RPE) detachment. The evaluation of typical forms of CSC showed a leakage point with uniform dye spread (inkblot) in 88.81% and 11.19% with a smoke-stack phenomenon. Regarding the leakage points, 46.01% were located in the upper nasal quadrant, 23.27% in the upper temporal quadrant, 19.18% in the lower nasal quadrant, 11.01% in the lower temporal quadrant and 0.53% in the subfoveal area.

Conclusions: In our series men were affected approximately two times more often then women, most of them with a unilateral involvement and in around the fourth decade of life. About 90% of the patients presented the typical forms, with 1 or 2 inkblot points or leakage. The superior nasal quadrant was the most affected. The isolated RPE detachment rarely occurred. Decompensation of RPE affected about 10% of the patients.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1590/s0004-27492005000300008DOI Listing
March 2006

[Comparative study of the density of corneal endothelial cells after phacoemulsification by the "divide and conquer" and "quick chop" techniques].

Arq Bras Oftalmol 2005 Jan-Feb;68(1):109-15. Epub 2005 Mar 30.

Hospital Universitário Clementino Fraga Filho, Departamento de Oftalmologia, Universidade Federal do Rio de Janeiro, Faculdade de Medicina.

Purpose: Since one of the most implicated factors in corneal endothelial cell loss after phacoemulsification is the ultrasound time, and that the "quick chop" technique utilizes less ultrasound time, the objective of this study was to compare and analyze the reduction of the central corneal endothelial cell density between the patients submitted to the "divide and conquer" and "quick chop" techniques.

Methods: Fifty-six patients with grade 3 senile cataract were prospectively selected and submitted to endocapsular phacoemulsification by the "divide and conquer" (28 patients, group 1) and "quick chop" (28 patients, group 2) techniques. The non-contact corneal central specular microscopy performed pre- and postoperatively at one month, 3 months and 6 months, and the ultrasound time used for each surgery, were verified.

Results: We observed that the "divide and conquer" technique spent an average of 2.0 minutes of ultrasound time and the "quick chop", 1.1 minute; that the reduction of the central corneal endothelial cell density was significant for both techniques in the first postoperative month (16.5% in group 1 and 19.4% in group 2) and that the variations in central corneal endothelial cell density that followed, at the 3rd and 6th month were not significant. There was no statistically significant difference between the variation of the central corneal endothelial cell density that occurred with both techniques (Student's "t" test p=0.334; in the 1st postoperative month).

Conclusions: We concluded that the reduction of central corneal endothelial cell density was not statistically different between the two techniques.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1590/s0004-27492005000100020DOI Listing
February 2006