Harish Rajak

Harish Rajak

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Harish Rajak

Harish Rajak

Publications by authors named "Harish Rajak"

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32Publications

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Identification of Hydroxamic Acid Based Selective HDAC1 Inhibitors: Computer Aided Drug Design Studies.

Curr Comput Aided Drug Des 2019 ;15(2):145-166

Medicinal Chemistry Research Laboratory, Institute of Pharmaceutical Sciences, Guru Ghasidas University, Bilaspur- 495 009, (C.G.), India.

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http://dx.doi.org/10.2174/1573409914666180502113135DOI Listing
July 2019

Histone Deacetylase Inhibitors for the Treatment of Colorectal Cancer: Recent Progress and Future Prospects.

Curr Cancer Drug Targets 2017 ;17(5):456-466

Institute of Pharmaceutical Sciences, Guru Ghasidas University, Bilaspur. India.

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http://dx.doi.org/10.2174/1568009617666170109150134DOI Listing
March 2018

Synthesis, Characterization and Antimicrobial Evaluation of Lipid Based Norfloxacin Prodrug.

Curr Drug Deliv 2018 Feb;15(2):219-226

Institute of Pharmaceutical Sciences, Guru Ghasidas University, Bilaspur-495009, India.

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http://dx.doi.org/10.2174/1567201813666161018153852DOI Listing
February 2018

The Safety, Efficacy and Therapeutic Potential of Histone Deacetylase Inhibitors with Special Reference to Panobinostat in Gastrointestinal Tumors: A Review of Preclinical and Clinical Studies.

Curr Cancer Drug Targets 2018 ;18(8):720-736

Medicinal Chemistry Research Laboratory, Institute of Pharmaceutical Sciences, Guru Ghasidas University, Bilaspur- 495 009, (C.G.), India.

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http://www.eurekaselect.com/153634/article
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http://dx.doi.org/10.2174/1568009617666170630124643DOI Listing
January 2018

Pharmacophore Based 3D-QSAR, Virtual Screening and Docking Studies on Novel Series of HDAC Inhibitors with Thiophen Linker as Anticancer Agents.

Comb Chem High Throughput Screen 2016 ;19(9):735-751

SLT Institute of Pharmaceutical Sciences, Guru Ghasidas University, Bilaspur 495009, India.

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August 2017

Panobinostat as Pan-deacetylase Inhibitor for the Treatment of Pancreatic Cancer: Recent Progress and Future Prospects.

Oncol Ther 2016 10;4(1):73-89. Epub 2016 Jun 10.

Institute of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya, Bilaspur, Chhattisgarh 495 009 India.

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http://dx.doi.org/10.1007/s40487-016-0023-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315073PMC
June 2016

Synthesis, biological evaluation and molecular docking studies of 2-amino-3,4,5-trimethoxyaroylindole derivatives as novel anticancer agents.

Bioorg Med Chem Lett 2016 May 24;26(9):2115-8. Epub 2016 Mar 24.

Medicinal Chemistry Research Laboratory, SLT Institute of Pharmaceutical Sciences, Guru Ghasidas University, Bilaspur 495 009, C.G., India. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2016.03.081DOI Listing
May 2016

Drug Design Strategies for the Discovery of Novel Anticonvulsants Concerned with Four Site Binding Pharmacophoric Model Studies.

Cent Nerv Syst Agents Med Chem 2016 Apr 11. Epub 2016 Apr 11.

Institute of Pharmaceutical Sciences, Guru Ghasidas University, Bilaspur, India.

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April 2016

Novel pyrimidine based semicarbazones: Confirmation of four binding site pharmacophoric model hypothesis for antiepileptic activity.

Cent Nerv Syst Agents Med Chem 2016 Mar 30. Epub 2016 Mar 30.

Institute of Pharmaceutical Sciences, Guru Ghasidas University, Bilaspur, India.

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March 2016

Wound healing activity of Sida cordifolia Linn. in rats.

Indian J Pharmacol 2013 Sep-Oct;45(5):474-8

Pharmacognosy and Phytochemistry Laboratory, Faculty of Pharmacy, VNS Group of Institutions, Neelbud, Bhopal, Madhya Pradesh, India.

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http://www.ijp-online.com/text.asp?2013/45/5/474/117759
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http://dx.doi.org/10.4103/0253-7613.117759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793518PMC
May 2014

Insight view on possible role of fluoroquinolones in cancer therapy.

Curr Top Med Chem 2013 Aug;13(16):2076-96

Institute of Pharmaceutical Sciences, Kurukshetra University, Kurukshetra-136119, India.

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August 2013

Medicinal significance of benzothiazole scaffold: an insight view.

J Enzyme Inhib Med Chem 2013 Apr 3;28(2):240-66. Epub 2012 Oct 3.

Institute of Pharmaceutical Sciences, Kurukshetra University, Kurukshetra, India.

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http://www.tandfonline.com/doi/full/10.3109/14756366.2012.72
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http://dx.doi.org/10.3109/14756366.2012.720572DOI Listing
April 2013

Synthesis and biological evaluation of novel benzothiazole clubbed fluoroquinolone derivatives.

J Enzyme Inhib Med Chem 2013 Feb 10;28(1):1-10. Epub 2011 Oct 10.

Institute of Pharmaceutical Sciences, Kurukshetra University, Kurukshetra, India.

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http://www.tandfonline.com/doi/full/10.3109/14756366.2011.61
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http://dx.doi.org/10.3109/14756366.2011.611943DOI Listing
February 2013

Novel limonene and citral based 2,5-disubstituted-1,3,4-oxadiazoles: a natural product coupled approach to semicarbazones for antiepileptic activity.

Bioorg Med Chem Lett 2013 Feb 27;23(3):864-8. Epub 2012 Nov 27.

Medicinal Chemistry Research Laboratory, SLT Institute of Pharmaceutical Sciences, Guru Ghasidas University, Bilaspur 495 009, CG, India.

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https://linkinghub.elsevier.com/retrieve/pii/S0960894X120150
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http://dx.doi.org/10.1016/j.bmcl.2012.11.051DOI Listing
February 2013

Appraisal of GABA and PABA as linker: design and synthesis of novel benzamide based histone deacetylase inhibitors.

Eur J Med Chem 2012 Jul 11;53:390-7. Epub 2012 Apr 11.

Medicinal Chemistry Research Laboratory, SLT Institute of Pharmaceutical Sciences, Guru Ghasidas University, Bilaspur 495 009, CG, India.

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http://dx.doi.org/10.1016/j.ejmech.2012.03.058DOI Listing
July 2012

Synthesis and antiepileptic activity of some novel semicarbazones containing 1,3,4-thiadiazole and quinazoline ring.

Acta Pol Pharm 2012 Mar-Apr;69(2):253-61

Medicinal Chemistry Research Laboratory, SLT Institute of Pharmaceutical Sciences, Guru Ghasidas University, Bilaspur-495 009, India.

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May 2012

Synthesis of some novel 4-(4-chlorophenyl)-6-p-tolyl-(+)-pyrimidine derivatives and their anticonvulsant activity.

Acta Pol Pharm 2011 Nov-Dec;68(6):993-7

Department of Chemistry, SLT Institute of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya (Central University), Bilaspur-495 009 (C.G.), India.

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December 2011

2,5-Disubstituted-1,3,4-oxadiazoles/thiadiazole as surface recognition moiety: design and synthesis of novel hydroxamic acid based histone deacetylase inhibitors.

Bioorg Med Chem Lett 2011 Oct 8;21(19):5735-8. Epub 2011 Aug 8.

Medicinal Chemistry Research Laboratory, SLT Institute of Pharmaceutical Sciences, Guru Ghasidas University, Bilaspur 495 009, CG, India.

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http://dx.doi.org/10.1016/j.bmcl.2011.08.022DOI Listing
October 2011

Design, synthesis, and evaluation of thiazolidinone derivatives as antimicrobial and anti-viral agents.

Chem Biol Drug Des 2011 Sep 8;78(3):464-70. Epub 2011 Jul 8.

Faculty of Pharmacy, AIMST University, Semeling - 08100, Kedah, Malaysia.

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http://dx.doi.org/10.1111/j.1747-0285.2011.01149.xDOI Listing
September 2011

A novel series of 2,5-disubstituted 1,3,4-oxadiazoles: synthesis and SAR study for their anticonvulsant activity.

Chem Biol Drug Des 2011 Feb;77(2):152-8

SLT Institute of Pharmaceutical Sciences, Guru Ghasidas University, Bilaspur 495 009, Chhattisgarh, India.

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http://dx.doi.org/10.1111/j.1747-0285.2010.01066.xDOI Listing
February 2011

Synthesis and anticonvulsant evaluation of some novel 2,5-disubstituted 1,3,4-thiadiazoles: pharmacophore model studies.

Acta Pol Pharm 2010 Sep-Oct;67(5):503-10

Medicinal Chemistry Research Laboratory, SLT Institute of Pharmaceutical Sciences, Guru Ghasidas University, Bilaspur-495 009, India.

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http://www.ptfarm.pl/pub/File/Acta_Poloniae/2010/5/503.pdf
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October 2010

Design, synthesis, and pharmacological evaluation of novel oxadiazole and oxadiazoline analogs as anti-inflammatory agents.

J Enzyme Inhib Med Chem 2010 Aug;25(4):492-501

Medicinal Chemistry Division, SLT Institute of Pharmaceutical Sciences, Guru Ghasidas University, Bilaspur, India.

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http://dx.doi.org/10.3109/14756360903282841DOI Listing
August 2010

Novel semicarbazones based 2,5-disubstituted-1,3,4-oxadiazoles: one more step towards establishing four binding site pharmacophoric model hypothesis for anticonvulsant activity.

Bioorg Med Chem Lett 2010 Jul 20;20(14):4168-72. Epub 2010 May 20.

Medicinal Chemistry Research Laboratory, SLT Institute of Pharmaceutical Sciences, Guru Ghasidas University, Bilaspur 495 009, CG, India.

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http://linkinghub.elsevier.com/retrieve/pii/S0960894X1000700
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http://dx.doi.org/10.1016/j.bmcl.2010.05.059DOI Listing
July 2010

Design, synthesis and biological evaluation of some novel benzimidazole derivatives for their potential anticonvulsant activity.

Arch Pharm Res 2010 Jul 27;33(7):971-80. Epub 2010 Jul 27.

Department of Pharmaceutical Chemistry, VNS Institute of Pharmacy, Bhopal, MP, India.

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http://dx.doi.org/10.1007/s12272-010-0701-8DOI Listing
July 2010

Synthesis of novel 2,5-disubstituted 1,3,4-thiadiazoles for their potential anticonvulsant activity: pharmacophoric model studies.

Arch Pharm (Weinheim) 2009 Aug;342(8):453-61

Medicinal Chemistry Division, SLT Institute of Pharmaceutical Sciences, Guru Ghasidas University, Bilaspur, (CG), India.

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http://dx.doi.org/10.1002/ardp.200800213DOI Listing
August 2009

Synthesis and local anesthetic activity of some novel N-[5-(4-substituted)phenyl-1,3,4-oxadiazol-2-yl]-2-(substituted)-acetamides.

Arch Pharm (Weinheim) 2008 Apr;341(4):247-61

Medicinal Chemistry Division, SLT Institute of Pharmaceutical Sciences, Guru Ghasidas University, Bilaspur, India.

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http://dx.doi.org/10.1002/ardp.200700146DOI Listing
April 2008

Synthesis of some novel oxadiazole and oxadiazoline analogues for their antiinflammatory activity.

Yakugaku Zasshi 2007 Oct;127(10):1757-64

SLT Institute of Pharmaceutical Sciences, Guru Ghasidas University, Bilaspur-495 009, India.

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http://dx.doi.org/10.1248/yakushi.127.1757DOI Listing
October 2007

Synthesis of Schiff bases of 2-amino-5-aryl-1,3,4-oxadiazoles and their evaluation for antimicrobial activities.

J Gen Appl Microbiol 2005 Apr;51(2):133-41

Pharmaceutical Chemistry Research Laboratory, Department of Pharmaceutical Sciences, Dr. Hari Singh Gour University, Sagar, India.

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April 2005