Haran Sivakumaran

Haran Sivakumaran

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Haran Sivakumaran

Haran Sivakumaran

Publications by authors named "Haran Sivakumaran"

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Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation.

Authors:
Maya Ghoussaini Juliet D French Kyriaki Michailidou Silje Nord Jonathan Beesley Sander Canisus Kristine M Hillman Susanne Kaufmann Haran Sivakumaran Mahdi Moradi Marjaneh Jason S Lee Joe Dennis Manjeet K Bolla Qin Wang Ed Dicks Roger L Milne John L Hopper Melissa C Southey Marjanka K Schmidt Annegien Broeks Kenneth Muir Artitaya Lophatananon Peter A Fasching Matthias W Beckmann Olivia Fletcher Nichola Johnson Elinor J Sawyer Ian Tomlinson Barbara Burwinkel Frederik Marme Pascal Guénel Thérèse Truong Stig E Bojesen Henrik Flyger Javier Benitez Anna González-Neira M Rosario Alonso Guillermo Pita Susan L Neuhausen Hoda Anton-Culver Hermann Brenner Volker Arndt Alfons Meindl Rita K Schmutzler Hiltrud Brauch Ute Hamann Daniel C Tessier Daniel Vincent Heli Nevanlinna Sofia Khan Keitaro Matsuo Hidemi Ito Thilo Dörk Natalia V Bogdanova Annika Lindblom Sara Margolin Arto Mannermaa Veli-Matti Kosma Anna H Wu David Van Den Berg Diether Lambrechts Giuseppe Floris Jenny Chang-Claude Anja Rudolph Paolo Radice Monica Barile Fergus J Couch Emily Hallberg Graham G Giles Christopher A Haiman Loic Le Marchand Mark S Goldberg Soo H Teo Cheng Har Yip Anne-Lise Borresen-Dale Wei Zheng Qiuyin Cai Robert Winqvist Katri Pylkäs Irene L Andrulis Peter Devilee Rob A E M Tollenaar Montserrat García-Closas Jonine Figueroa Per Hall Kamila Czene Judith S Brand Hatef Darabi Mikael Eriksson Maartje J Hooning Linetta B Koppert Jingmei Li Xiao-Ou Shu Ying Zheng Angela Cox Simon S Cross Mitul Shah Valerie Rhenius Ji-Yeob Choi Daehee Kang Mikael Hartman Kee Seng Chia Maria Kabisch Diana Torres Craig Luccarini Don M Conroy Anna Jakubowska Jan Lubinski Suleeporn Sangrajrang Paul Brennan Curtis Olswold Susan Slager Chen-Yang Shen Ming-Feng Hou Anthony Swerdlow Minouk J Schoemaker Jacques Simard Paul D P Pharoah Vessela Kristensen Georgia Chenevix-Trench Douglas F Easton Alison M Dunning Stacey L Edwards

Am J Hum Genet 2016 Oct 15;99(4):903-911. Epub 2016 Sep 15.

Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, QLD 4006, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.07.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065698PMC
October 2016

Shutdown of HIV-1 Transcription in T Cells by Nullbasic, a Mutant Tat Protein.

MBio 2016 07 5;7(4). Epub 2016 Jul 5.

Department of Cell and Molecular Biology, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia

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http://dx.doi.org/10.1128/mBio.00518-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958243PMC
July 2016

Point Mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant.

Am J Hum Genet 2016 05 14;98(5):830-842. Epub 2016 Apr 14.

Department of Genetics and Computational Biology, QIMR Berghofer, Herston, QLD 4029, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863475PMC
May 2016

Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170.

Authors:
Alison M Dunning Kyriaki Michailidou Karoline B Kuchenbaecker Deborah Thompson Juliet D French Jonathan Beesley Catherine S Healey Siddhartha Kar Karen A Pooley Elena Lopez-Knowles Ed Dicks Daniel Barrowdale Nicholas A Sinnott-Armstrong Richard C Sallari Kristine M Hillman Susanne Kaufmann Haran Sivakumaran Mahdi Moradi Marjaneh Jason S Lee Margaret Hills Monika Jarosz Suzie Drury Sander Canisius Manjeet K Bolla Joe Dennis Qin Wang John L Hopper Melissa C Southey Annegien Broeks Marjanka K Schmidt Artitaya Lophatananon Kenneth Muir Matthias W Beckmann Peter A Fasching Isabel Dos-Santos-Silva Julian Peto Elinor J Sawyer Ian Tomlinson Barbara Burwinkel Frederik Marme Pascal Guénel Thérèse Truong Stig E Bojesen Henrik Flyger Anna González-Neira Jose I A Perez Hoda Anton-Culver Lee Eunjung Volker Arndt Hermann Brenner Alfons Meindl Rita K Schmutzler Hiltrud Brauch Ute Hamann Kristiina Aittomäki Carl Blomqvist Hidemi Ito Keitaro Matsuo Natasha Bogdanova Thilo Dörk Annika Lindblom Sara Margolin Veli-Matti Kosma Arto Mannermaa Chiu-Chen Tseng Anna H Wu Diether Lambrechts Hans Wildiers Jenny Chang-Claude Anja Rudolph Paolo Peterlongo Paolo Radice Janet E Olson Graham G Giles Roger L Milne Christopher A Haiman Brian E Henderson Mark S Goldberg Soo H Teo Cheng Har Yip Silje Nord Anne-Lise Borresen-Dale Vessela Kristensen Jirong Long Wei Zheng Katri Pylkäs Robert Winqvist Irene L Andrulis Julia A Knight Peter Devilee Caroline Seynaeve Jonine Figueroa Mark E Sherman Kamila Czene Hatef Darabi Antoinette Hollestelle Ans M W van den Ouweland Keith Humphreys Yu-Tang Gao Xiao-Ou Shu Angela Cox Simon S Cross William Blot Qiuyin Cai Maya Ghoussaini Barbara J Perkins Mitul Shah Ji-Yeob Choi Daehee Kang Soo Chin Lee Mikael Hartman Maria Kabisch Diana Torres Anna Jakubowska Jan Lubinski Paul Brennan Suleeporn Sangrajrang Christine B Ambrosone Amanda E Toland Chen-Yang Shen Pei-Ei Wu Nick Orr Anthony Swerdlow Lesley McGuffog Sue Healey Andrew Lee Miroslav Kapuscinski Esther M John Mary Beth Terry Mary B Daly David E Goldgar Saundra S Buys Ramunas Janavicius Laima Tihomirova Nadine Tung Cecilia M Dorfling Elizabeth J van Rensburg Susan L Neuhausen Bent Ejlertsen Thomas V O Hansen Ana Osorio Javier Benitez Rachel Rando Jeffrey N Weitzel Bernardo Bonanni Bernard Peissel Siranoush Manoukian Laura Papi Laura Ottini Irene Konstantopoulou Paraskevi Apostolou Judy Garber Muhammad Usman Rashid Debra Frost Louise Izatt Steve Ellis Andrew K Godwin Norbert Arnold Dieter Niederacher Kerstin Rhiem Nadja Bogdanova-Markov Charlotte Sagne Dominique Stoppa-Lyonnet Francesca Damiola Olga M Sinilnikova Sylvie Mazoyer Claudine Isaacs Kathleen B M Claes Kim De Leeneer Miguel de la Hoya Trinidad Caldes Heli Nevanlinna Sofia Khan Arjen R Mensenkamp Maartje J Hooning Matti A Rookus Ava Kwong Edith Olah Orland Diez Joan Brunet Miquel Angel Pujana Jacek Gronwald Tomasz Huzarski Rosa B Barkardottir Rachel Laframboise Penny Soucy Marco Montagna Simona Agata Manuel R Teixeira Sue Kyung Park Noralane Lindor Fergus J Couch Marc Tischkowitz Lenka Foretova Joseph Vijai Kenneth Offit Christian F Singer Christine Rappaport Catherine M Phelan Mark H Greene Phuong L Mai Gad Rennert Evgeny N Imyanitov Peter J Hulick Kelly-Anne Phillips Marion Piedmonte Anna Marie Mulligan Gord Glendon Anders Bojesen Mads Thomassen Maria A Caligo Sook-Yee Yoon Eitan Friedman Yael Laitman Ake Borg Anna von Wachenfeldt Hans Ehrencrona Johanna Rantala Olufunmilayo I Olopade Patricia A Ganz Robert L Nussbaum Simon A Gayther Katherine L Nathanson Susan M Domchek Banu K Arun Gillian Mitchell Beth Y Karlan Jenny Lester Gertraud Maskarinec Christy Woolcott Christopher Scott Jennifer Stone Carmel Apicella Rulla Tamimi Robert Luben Kay-Tee Khaw Åslaug Helland Vilde Haakensen Mitch Dowsett Paul D P Pharoah Jacques Simard Per Hall Montserrat García-Closas Celine Vachon Georgia Chenevix-Trench Antonis C Antoniou Douglas F Easton Stacey L Edwards

Nat Genet 2016 Apr 29;48(4):374-86. Epub 2016 Feb 29.

Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1038/ng.3521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938803PMC
April 2016

The protein arginine methyltransferase PRMT6 inhibits HIV-1 Tat nucleolar retention.

Biochim Biophys Acta 2016 Feb 2;1863(2):254-62. Epub 2015 Dec 2.

Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3800, Australia; ARC Centre of Excellence for Biotechnology and Development, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01674889150040
Publisher Site
http://dx.doi.org/10.1016/j.bbamcr.2015.11.019DOI Listing
February 2016

Germline polymorphisms in an enhancer of PSIP1 are associated with progression-free survival in epithelial ovarian cancer.

Oncotarget 2016 Feb;7(6):6353-68

QIMR Berghofer Medical Research Institute, Brisbane, Australia.

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http://dx.doi.org/10.18632/oncotarget.7047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872719PMC
February 2016

A mutant tat protein inhibits HIV-1 reverse transcription by targeting the reverse transcription complex.

J Virol 2015 May 11;89(9):4827-36. Epub 2015 Feb 11.

QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia Australian Infectious Disease Research Centre at the University of Queensland, St. Lucia, Queensland, Queensland, Australia

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http://dx.doi.org/10.1128/JVI.03440-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403448PMC
May 2015

Synergistic activity of tenofovir and nevirapine combinations released from polycaprolactone matrices for potential enhanced prevention of HIV infection through the vaginal route.

Eur J Pharm Biopharm 2014 Oct 2;88(2):406-14. Epub 2014 Jun 2.

The University of Queensland, School of Pharmacy, St Lucia, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ejpb.2014.05.018DOI Listing
October 2014

Evaluation of polycaprolactone matrices for sustained vaginal delivery of nevirapine in the prevention of heterosexual HIV transmission.

J Pharm Sci 2014 Jul 27;103(7):2107-2115. Epub 2014 May 27.

School of Pharmacy, The University of Queensland, St. Lucia, Queensland 4072, Australia. Electronic address:

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http://dx.doi.org/10.1002/jps.24030DOI Listing
July 2014

An evaluation of polycaprolactone matrices for vaginal delivery of the antiviral, tenofovir, in preventing heterosexual transmission of HIV.

J Pharm Sci 2013 Oct 31;102(10):3725-35. Epub 2013 Jul 31.

The University of Queensland, Pharmacy Australia Centre of Excellence, Woolloongabba, QLD 4102, Australia.

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http://dx.doi.org/10.1002/jps.23684DOI Listing
October 2013

Nullbasic, a potent anti-HIV tat mutant, induces CRM1-dependent disruption of HIV rev trafficking.

PLoS One 2012 10;7(12):e51466. Epub 2012 Dec 10.

Queensland Institute of Medical Research, Molecular Virology Laboratory, Herston, Brisbane, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0051466PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519632PMC
June 2013

Overexpression of PRMT6 does not suppress HIV-1 Tat transactivation in cells naturally lacking PRMT6.

Virol J 2013 Jun 24;10:207. Epub 2013 Jun 24.

Queensland Institute of Medical Research, Molecular Virology Laboratory, 300 Herston Road, Herston, Brisbane 4006, Australia.

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http://virologyj.biomedcentral.com/articles/10.1186/1743-422
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http://dx.doi.org/10.1186/1743-422X-10-207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695826PMC
June 2013

A mutant Tat protein provides strong protection from HIV-1 infection in human CD4+ T cells.

Hum Gene Ther 2013 Mar 1;24(3):270-82. Epub 2013 Mar 1.

Queensland Institute of Medical Research, Molecular Virology Laboratory, Herston, Brisbane, Queensland 4006, Australia .

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http://dx.doi.org/10.1089/hum.2012.176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696950PMC
March 2013

Eukaryotic elongation factor 1 complex subunits are critical HIV-1 reverse transcription cofactors.

Proc Natl Acad Sci U S A 2012 Jun 24;109(24):9587-92. Epub 2012 May 24.

Department of Cell and Molecular Biology, Queensland Institute of Medical Research, Herston, Queensland, 4029, Australia.

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http://dx.doi.org/10.1073/pnas.1204673109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386134PMC
June 2012

Ivermectin is a specific inhibitor of importin α/β-mediated nuclear import able to inhibit replication of HIV-1 and dengue virus.

Biochem J 2012 May;443(3):851-6

Nuclear Signalling Laboratory, Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3800, Australia.

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http://dx.doi.org/10.1042/BJ20120150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327999PMC
May 2012

Arginine methylation increases the stability of human immunodeficiency virus type 1 Tat.

J Virol 2009 Nov 2;83(22):11694-703. Epub 2009 Sep 2.

Division of Infectious Diseases, Queensland Institute of Medical Research, Herston, Queensland 4006, Australia.

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http://dx.doi.org/10.1128/JVI.00499-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2772670PMC
November 2009

Potent inhibition of HIV-1 replication by a Tat mutant.

PLoS One 2009 Nov 10;4(11):e7769. Epub 2009 Nov 10.

Division of Infectious Diseases, Queensland Institute of Medical Research, Herston, Queensland, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0007769PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768900PMC
November 2009

Functional relevance of nonsynonymous mutations in the HIV-1 tat gene within an epidemiologically-linked transmission cohort.

Virol J 2007 Oct 25;4:107. Epub 2007 Oct 25.

Division of Infectious Diseases and Immunology, Queensland Institute of Medical Research, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1186/1743-422X-4-107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174444PMC
October 2007

Differential induction of antiviral effects against West Nile virus in primary mouse macrophages derived from flavivirus-susceptible and congenic resistant mice by alpha/beta interferon and poly(I-C).

J Virol 2005 Feb;79(3):1753-64

Microbiology, School of Biomedical and Chemical Sciences, University of Western Australia, 35 Stirling Hwy., Crawley, Western Australia 6009.

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http://dx.doi.org/10.1128/JVI.79.3.1753-1764.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC544086PMC
February 2005