Publications by authors named "Harald Steiner"

89Publications

γ-Secretase cleavage of the Alzheimer risk factor TREM2 is determined by its intrinsic structural dynamics.

EMBO J 2020 Oct 24;39(20):e104247. Epub 2020 Aug 24.

Bavarian NMR Center at the Department of Chemistry and Institute for Advanced Study, Technical University of Munich, Garching, Germany.

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October 2020

Understanding intramembrane proteolysis by γ-secretase.

Authors:
Harald Steiner

Semin Cell Dev Biol 2020 09 18;105:1-2. Epub 2020 Jun 18.

Biomedical Center (BMC), Metabolic Biochemistry, Ludwig-Maximilians-University, Munich, Feodor-Lynen-Str. 17, 81377, Munich, Germany; German Center for Neurodegenerative Diseases (DZNE), Munich, Feodor-Lynen-Str. 17, 81377, Munich, Germany. Electronic address:

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September 2020

Substrate recruitment by γ-secretase.

Semin Cell Dev Biol 2020 09 22;105:54-63. Epub 2020 Apr 22.

German Center for Neurodegenerative Diseases (DZNE), Munich, Feodor-Lynen-Str. 17, 81377, Munich, Germany; Biomedical Center (BMC), Metabolic Biochemistry, Ludwig-Maximilians-University, Munich, Feodor-Lynen-Str. 17, 81377, Munich, Germany. Electronic address:

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September 2020

Pathogenic Aβ generation in familial Alzheimer's disease: novel mechanistic insights and therapeutic implications.

Curr Opin Neurobiol 2020 04 24;61:73-81. Epub 2020 Feb 24.

Biomedical Center (BMC), Metabolic Biochemistry, Ludwig-Maximilians-University, Munich, Feodor-Lynen-Str. 17, 81377 Munich, Germany; German Center for Neurodegenerative Diseases (DZNE), Munich, Feodor-Lynen-Str. 17, 81377 Munich, Germany. Electronic address:

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April 2020

Photo-controlled delivery of very long chain fatty acids to cell membranes and modulation of membrane protein function.

Biochim Biophys Acta Biomembr 2020 05 20;1862(5):183200. Epub 2020 Jan 20.

Leiden Institute of Chemistry, Leiden University, 2300 RA Leiden, the Netherlands. Electronic address:

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May 2020

Aβ43-producing PS1 FAD mutants cause altered substrate interactions and respond to γ-secretase modulation.

EMBO Rep 2020 01 25;21(1):e47996. Epub 2019 Nov 25.

Biomedical Center (BMC), Metabolic Biochemistry, Ludwig-Maximilians-University, Munich, Germany.

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January 2020

Identification of a rare presenilin 1 single amino acid deletion mutation (F175del) with unusual amyloid-β processing effects.

Neurobiol Aging 2019 12 20;84:241.e5-241.e11. Epub 2019 Sep 20.

Department of Neurology, Ludwig-Maximilians-Universität München, Munich, Germany; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany. Electronic address:

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December 2019

Comparison of Strategies for the Determination of Sterol Sulfates via GC-MS Leading to a Novel Deconjugation-Derivatization Protocol.

Molecules 2019 Jun 26;24(13). Epub 2019 Jun 26.

Department of Pharmacy-Center for Drug Research, Ludwig-Maximilians University Munich, Butenandtstraße 5-13, 81377 Munich, Germany.

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June 2019

Making the final cut: pathogenic amyloid-β peptide generation by γ-secretase.

Cell Stress 2018 Oct 28;2(11):292-310. Epub 2018 Oct 28.

Neuropsychiatry, Department of Integrated Medicine, Division of Internal Medicine, Osaka University Graduate School of Medicine, Suita, Japan.

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October 2018

Modulating Hinge Flexibility in the APP Transmembrane Domain Alters γ-Secretase Cleavage.

Biophys J 2019 06 3;116(11):2103-2120. Epub 2019 May 3.

Biomedical Center (BMC), Metabolic Biochemistry, Ludwig-Maximilians-University, Munich, Germany; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany. Electronic address:

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June 2019

A Thermal Flow Sensor Based on Printed Circuit Technology in Constant Temperature Mode for Various Fluids.

Sensors (Basel) 2019 Mar 2;19(5). Epub 2019 Mar 2.

Institute of Sensor and Actuator Systems, TU Wien, Gusshausstrasse 27-29, 1040 Vienna, Austria.

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March 2019

Dual Resonator MEMS Magnetic Field Gradiometer.

Sensors (Basel) 2019 Jan 25;19(3). Epub 2019 Jan 25.

Institute of Sensor and Actuator Systems, TU Wien, 1040 Vienna, Austria.

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January 2019