Harald Binder

Harald Binder

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Delayed Intracranial Hemorrhage in Patients with Head Trauma and Antithrombotic Therapy.

J Clin Med 2019 Oct 25;8(11). Epub 2019 Oct 25.

Department of Orthopedics and Trauma-Surgery, Medical University of Vienna, 1090 Vienna, Austria.

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http://dx.doi.org/10.3390/jcm8111780DOI Listing
October 2019

Power of the Wilcoxon-Mann-Whitney test for non-inferiority in the presence of death-censored observations.

Biom J 2019 Sep 19;61(5):1187-1200. Epub 2018 Sep 19.

Institute of Medical Biometry and Statistics, Medical Faculty and Medical Center - University Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1002/bimj.201700296DOI Listing
September 2019

Deconstructing and Reconstructing Resilience: A Dynamic Network Approach.

Perspect Psychol Sci 2019 09 31;14(5):765-777. Epub 2019 Jul 31.

5 Department of Psychiatry, University of Cambridge.

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http://dx.doi.org/10.1177/1745691619855637DOI Listing
September 2019

Comparison of Different Hypotheses Regarding the Spread of Alzheimer's Disease Using Markov Random Fields and Multimodal Imaging.

J Alzheimers Dis 2018 ;65(3):731-746

German Center for Neurodegenerative Diseases (DZNE), Site Rostock/Greifswald, Rostock, Germany.

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http://dx.doi.org/10.3233/JAD-161197DOI Listing
August 2019

Fatigue in survivors of malignant melanoma and its determinants: a register-based cohort study.

Support Care Cancer 2019 Aug 11;27(8):2809-2818. Epub 2018 Dec 11.

Department of Psychosomatic Medicine and Psychotherapy, University Medical Center of the Johannes Gutenberg-University Mainz, Untere Zahlbacher Str. 8, 55131, Mainz, Germany.

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http://dx.doi.org/10.1007/s00520-018-4587-1DOI Listing
August 2019

A Queue-Poll Extension and DataSHIELD: Standardised, Monitored, Indirect and Secure Access to Sensitive Data.

Stud Health Technol Inform 2019 ;258:115-119

Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center, University of Freiburg.

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August 2019

A multivariable approach for risk markers from pooled molecular data with only partial overlap.

BMC Med Genet 2019 07 19;20(1):128. Epub 2019 Jul 19.

Institute for Medical Biometry and Statistics, Faculty of Medicine and Medical Center - University of Freiburg, Stefan-Meier-Straße 26, Freiburg, 79104, Germany.

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http://dx.doi.org/10.1186/s12881-019-0849-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642584PMC
July 2019

Meta-analyses identify differentially expressed micrornas in Parkinson's disease.

Ann Neurol 2019 Jun;85(6):835-851

Genetic and Molecular Epidemiology Group, Lübeck Interdisciplinary Platform for Genome Analytics, Institutes of Neurogenetics & Cardiogenetics, University of Lübeck, Lübeck, Germany.

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http://dx.doi.org/10.1002/ana.25490DOI Listing
June 2019

pcaExplorer: an R/Bioconductor package for interacting with RNA-seq principal components.

BMC Bioinformatics 2019 Jun 13;20(1):331. Epub 2019 Jun 13.

Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center - University of Freiburg, Stefan-Meier-Str. 26, Freiburg, 79104, Germany.

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http://dx.doi.org/10.1186/s12859-019-2879-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567655PMC
June 2019

Feasibility and utility of a cognitive screening for risk stratification in hospitalized older patients.

Int J Geriatr Psychiatry 2019 04 18;34(4):588-593. Epub 2019 Jan 18.

Department of Psychiatry and Psychotherapy, University Medical Center Mainz, Mainz, Germany.

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http://dx.doi.org/10.1002/gps.5056DOI Listing
April 2019

Uncontrolled Diabetes Mellitus Has No Major Influence on the Platelet Transcriptome.

Biomed Res Int 2018 1;2018:8989252. Epub 2018 Nov 1.

Institut für Experimentelle und Klinische Pharmakologie und Toxikologie, Albert-Ludwigs-Universität Freiburg, D-79104 Freiburg, Germany.

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http://dx.doi.org/10.1155/2018/8989252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241365PMC
March 2019

The buried knot technique for all inside graft link preparation leads to superior biomechanical graft link stability.

Sci Rep 2019 Feb 6;9(1):1488. Epub 2019 Feb 6.

Department of Orthopedics and Trauma Surgery, Division of Trauma Surgery, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1038/s41598-018-38150-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365500PMC
February 2019

Promoter-proximal pausing mediated by the exon junction complex regulates splicing.

Nat Commun 2019 01 31;10(1):521. Epub 2019 Jan 31.

Laboratory of RNA Epigenetics, Institute of Molecular Biology (IMB), 55128, Mainz, Germany.

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http://dx.doi.org/10.1038/s41467-019-08381-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355915PMC
January 2019

Investigation of intraocular pressure fluctuation as a risk factor of glaucoma progression.

Clin Ophthalmol 2019 18;13:9-16. Epub 2018 Dec 18.

Department of Ophthalmology, University Medical Center Mainz, Mainz, Germany,

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http://dx.doi.org/10.2147/OPTH.S186526DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302802PMC
December 2018

Modeling Activity Tracker Data Using Deep Boltzmann Machines.

Stud Health Technol Inform 2018 ;253:155-159

Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center - University of Freiburg.

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November 2018

PanCareLIFE: The scientific basis for a European project to improve long-term care regarding fertility, ototoxicity and health-related quality of life after cancer occurring among children and adolescents.

Eur J Cancer 2018 11 29;103:227-237. Epub 2018 Sep 29.

German Childhood Cancer Registry (GCCR), Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center, Mainz, Germany.

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http://dx.doi.org/10.1016/j.ejca.2018.08.007DOI Listing
November 2018

Feasibility of sample size calculation for RNA-seq studies.

Brief Bioinform 2018 07;19(4):713-720

Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center Johannes Gutenberg University Mainz, Langenbeckstr, Mainz, Germany.

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http://dx.doi.org/10.1093/bib/bbw144DOI Listing
July 2018

Mechanisms and modulators of cognitive training gain transfer in cognitively healthy aging: study protocol of the AgeGain study.

Trials 2018 Jun 27;19(1):337. Epub 2018 Jun 27.

Department of Psychiatry and Psychotherapy, University Medical Center Mainz, Untere Zahlbacher Straße 8, 55131, Mainz, Germany.

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http://dx.doi.org/10.1186/s13063-018-2688-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020358PMC
June 2018

Time-to-first-event versus recurrent-event analysis: points to consider for selecting a meaningful analysis strategy in clinical trials with composite endpoints.

Clin Res Cardiol 2018 May 16;107(5):437-443. Epub 2018 Feb 16.

Institute of Medical Biostatistics, Epidemiology and Informatics, University of Mainz, Mainz, Germany.

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http://dx.doi.org/10.1007/s00392-018-1205-7DOI Listing
May 2018

Determinants of illness-specific social support and its relation to distress in long-term melanoma survivors.

BMC Public Health 2018 04 17;18(1):511. Epub 2018 Apr 17.

Department of Psychosomatic Medicine and Psychotherapy, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.

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http://dx.doi.org/10.1186/s12889-018-5401-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904995PMC
April 2018

The immune contexture of hepatocellular carcinoma predicts clinical outcome.

Sci Rep 2018 03 29;8(1):5351. Epub 2018 Mar 29.

Institute of Translational Immunology and Research Centre for Immunotherapy, University Medical Centre of the Johannes Gutenberg University Mainz, Mainz, Germany.

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http://dx.doi.org/10.1038/s41598-018-21937-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876395PMC
March 2018

On the necessity and design of studies comparing statistical methods.

Biom J 2018 01 29;60(1):216-218. Epub 2017 Nov 29.

Institute for Medical Biometry and Statistics, Faculty of Medicine and Medical Center, University of Freiburg, Stefan-Meier-Str. 26, 79104, Freiburg, Germany.

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http://dx.doi.org/10.1002/bimj.201700129DOI Listing
January 2018

Partitioned learning of deep Boltzmann machines for SNP data.

Bioinformatics 2017 Oct;33(20):3173-3180

Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center, 55131 Mainz, Germany.

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http://dx.doi.org/10.1093/bioinformatics/btx408DOI Listing
October 2017

Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study.

PLoS One 2017 20;12(1):e0167742. Epub 2017 Jan 20.

Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0167742PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249120PMC
August 2017

Retinal vessel metrics: normative data and their use in systemic hypertension: results from the Gutenberg Health Study.

J Hypertens 2017 08;35(8):1635-1645

aDepartment of Ophthalmology bDepartment of Preventive Cardiology and Preventive Medicine, Center for Cardiology I cInstitute of Medical Biostatistics, Epidemiology and Informatics, Division of Biostatistics and Bioinformatics dDepartment of Psychosomatic Medicine and Psychotherapy eInstitute of Clinical Chemistry and Laboratory Medicine fCenter for Thrombosis and Hemostasis, University Medical Center gDZHK (German Center for Cardiovascular Research), Partner Site Rhine Main, Langenbeckstr. 1, Mainz, Germany hDepartment of Ophthalmology, University Hospital Bern, Bern, Switzerland iDardenne Eye Hospital, Bonn-Bad Godesberg, Germany.

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http://dx.doi.org/10.1097/HJH.0000000000001380DOI Listing
August 2017

Identifying Prognostic SNPs in Clinical Cohorts: Complementing Univariate Analyses by Resampling and Multivariable Modeling.

PLoS One 2016 9;11(5):e0155226. Epub 2016 May 9.

Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center Johannes Gutenberg University Mainz, Mainz, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0155226PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861340PMC
July 2017

Noise Annoyance Is Associated with Depression and Anxiety in the General Population- The Contribution of Aircraft Noise.

PLoS One 2016 19;11(5):e0155357. Epub 2016 May 19.

Medical Clinic for Cardiology, Angiology and Intensive Care Medicine, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0155357PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873188PMC
July 2017

A DAG-based comparison of interventional effect underestimation between composite endpoint and multi-state analysis in cardiovascular trials.

BMC Med Res Methodol 2017 Jul 4;17(1):92. Epub 2017 Jul 4.

Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center Johannes Gutenberg-University Mainz, Obere Zahlbacher Str. 69, Mainz, 55131, Germany.

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http://dx.doi.org/10.1186/s12874-017-0366-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496642PMC
July 2017

The experience of physicians in pharmacogenomic clinical decision support within eight German university hospitals.

Pharmacogenomics 2017 Jun 8;18(8):773-785. Epub 2017 Jun 8.

Chair of Medical Informatics, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

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http://dx.doi.org/10.2217/pgs-2017-0027DOI Listing
June 2017

Simulation of complex data structures for planning of studies with focus on biomarker comparison.

BMC Med Res Methodol 2017 Jun 13;17(1):90. Epub 2017 Jun 13.

Institute for Medical Biometry and Statistics, Faculty of Medicine and Medical Center - University of Freiburg, Stefan-Meier-Str. 26, Freiburg, 79104, Germany.

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http://dx.doi.org/10.1186/s12874-017-0364-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470184PMC
June 2017

Displaced juvenile Tillaux fractures : Surgical treatment and outcome.

Wien Klin Wochenschr 2017 Mar 17;129(5-6):169-175. Epub 2016 Aug 17.

Department of Trauma Surgery, Medical University Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

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http://dx.doi.org/10.1007/s00508-016-1059-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346147PMC
March 2017

PREVALENCE AND ASSOCIATIONS OF MYELINATED RETINAL NERVE FIBERS: Results From the Population-Based Gutenberg Health Study.

Retina 2016 Dec;36(12):2364-2370

*Department of Ophthalmology, University Medical Center Mainz, Mainz, Germany; †NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, United Kingdom; ‡Department of Ophthalmology, Philipps University of Marburg, Marburg, Germany; §Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Mainz, Germany; ¶Department of Biostatistics, University Medical Center Mainz, Mainz, Germany; and **Dardenne Eye Hospital, Bonn-Bad Godesberg, Germany.

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http://dx.doi.org/10.1097/IAE.0000000000001093DOI Listing
December 2016

Prospective validation of a blood-based 9-miRNA profile for early detection of breast cancer in a cohort of women examined by clinical mammography.

Mol Oncol 2016 12 1;10(10):1621-1626. Epub 2016 Nov 1.

Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark; Department of Oncology, Odense University Hospital, Odense, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.molonc.2016.10.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423135PMC
December 2016

Myopia and Cognitive Performance: Results From the Gutenberg Health Study.

Invest Ophthalmol Vis Sci 2016 Oct;57(13):5230-5236

Medical Psychology and Medical Sociology, University Medical Center Mainz, Germany 6Medical Psychology and Medical Sociology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1167/iovs.16-19507DOI Listing
October 2016

Integrating multiple molecular sources into a clinical risk prediction signature by extracting complementary information.

BMC Bioinformatics 2016 Aug 30;17(1):327. Epub 2016 Aug 30.

Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center Johannes Gutenberg University Mainz, Obere Zahlbacher Str. 69, Mainz, 55131, Germany.

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http://dx.doi.org/10.1186/s12859-016-1183-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004308PMC
August 2016

Home treatment of patients with low-risk pulmonary embolism with the oral factor Xa inhibitor rivaroxaban. Rationale and design of the HoT-PE Trial.

Thromb Haemost 2016 07 24;116(1):191-7. Epub 2016 Mar 24.

Stavros V. Konstantinides, MD, FESC, Center for Thrombosis and Hemostasis, University Medical Center Mainz, Langenbeckstrasse 1, Building 403, 55131 Mainz, Germany, Tel.: +49 6131 17 8382, Fax: +49 6131 17 3456, E-mail:

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http://dx.doi.org/10.1160/TH16-01-0004DOI Listing
July 2016

Antiphospholipid antibodies in a large population-based cohort: genome-wide associations and effects on monocyte gene expression.

Thromb Haemost 2016 07 21;116(1):115-23. Epub 2016 Apr 21.

Dr. Karl J. Lackner, Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Mainz, Langenbeckstrasse 1, D-55131 Mainz, Germany, Tel.: +49 6131 177190, E-mail:

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http://dx.doi.org/10.1160/TH15-12-0947DOI Listing
July 2016

Tracheostomy following anterior cervical spine fusion in trauma patients.

Int Orthop 2016 Jun 21;40(6):1157-62. Epub 2015 Jul 21.

Department of Trauma Surgery, Medical University of Vienna, Waehringerguertel 18-20, 1090, Vienna, Austria.

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http://dx.doi.org/10.1007/s00264-015-2913-5DOI Listing
June 2016

Psychosocial Care Needs of Melanoma Survivors: Are They Being Met?

PLoS One 2015 21;10(8):e0132754. Epub 2015 Aug 21.

Department of Psychosomatic Medicine and Psychotherapy, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0132754PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546620PMC
May 2016

Pitfalls of hypothesis tests and model selection on bootstrap samples: Causes and consequences in biometrical applications.

Biom J 2016 May 15;58(3):447-73. Epub 2015 Sep 15.

Department of Medical Informatics, Biometry and Epidemiology, University of Munich, Marchioninistr. 15, 81377 Munich, Germany.

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http://dx.doi.org/10.1002/bimj.201400246DOI Listing
May 2016

Stagewise pseudo-value regression for time-varying effects on the cumulative incidence.

Stat Med 2016 Mar 28;35(7):1144-58. Epub 2015 Oct 28.

Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center, Johannes Gutenberg University Mainz, 55101, Mainz, Germany.

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http://dx.doi.org/10.1002/sim.6770DOI Listing
March 2016

Bioresorbable Coronary Scaffold Thrombosis: Multicenter Comprehensive Analysis of Clinical Presentation, Mechanisms, and Predictors.

J Am Coll Cardiol 2016 Mar;67(8):921-31

Zentrum für Kardiologie, University Hospital Mainz, Mainz, Germany, and German Center for Cardiac and Vascular Research (DZHK), Standort Rhein-Main, Mainz, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2015.12.019DOI Listing
March 2016

Treatment of proximal humerus fractures in children and young adolescents.

Wien Klin Wochenschr 2016 Feb 6;128(3-4):120-4. Epub 2015 Nov 6.

Department of Trauma Surgery, Medical University Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

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http://dx.doi.org/10.1007/s00508-015-0879-3DOI Listing
February 2016

Disease Burden of Rotavirus Gastroenteritis in Children Residing in Germany: A Retrospective, Hospital-based Surveillance.

Pediatr Infect Dis J 2016 Jan;35(1):97-103

From the *Pediatric Department and †Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center of the Johannes Gutenberg University, Mainz, Germany; ‡Johannes Gutenberg University Mainz, Faculty of Economics, Mainz, Germany; §Klinikum der Landeshauptstadt Wiesbaden HSK, Dr Horst Schmidt Kliniken, Wiesbaden, Germany; ¶Pediatric Infectious Diseases, Department of Pediatrics, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; ‖Pediatric Department, University Hospital Carl Gustav Carus, Dresden, Germany; **Sanofi Pasteur MSD GmbH, Leimen, Germany; and ††Institute for Community Medicine, University Medicine of the Ernst-Moritz-Arndt University, Greifswald, Germany.

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http://dx.doi.org/10.1097/INF.0000000000000939DOI Listing
January 2016

Sex-specific differences in genetic and nongenetic determinants of mean platelet volume: results from the Gutenberg Health Study.

Blood 2016 Jan 30;127(2):251-9. Epub 2015 Oct 30.

Center of Thrombosis and Hemostasis, Preventive Cardiology and Medical Prevention, Department of Medicine II, and DZHK, Partner Site Rhein-Main, Mainz, Germany; and.

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http://dx.doi.org/10.1182/blood-2015-07-660308DOI Listing
January 2016

A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration.

Authors:
Paul S de Vries Daniel I Chasman Maria Sabater-Lleal Ming-Huei Chen Jennifer E Huffman Maristella Steri Weihong Tang Alexander Teumer Riccardo E Marioni Vera Grossmann Jouke J Hottenga Stella Trompet Martina Müller-Nurasyid Jing Hua Zhao Jennifer A Brody Marcus E Kleber Xiuqing Guo Jie Jin Wang Paul L Auer John R Attia Lisa R Yanek Tarunveer S Ahluwalia Jari Lahti Cristina Venturini Toshiko Tanaka Lawrence F Bielak Peter K Joshi Ares Rocanin-Arjo Ivana Kolcic Pau Navarro Lynda M Rose Christopher Oldmeadow Helene Riess Johanna Mazur Saonli Basu Anuj Goel Qiong Yang Mohsen Ghanbari Gonneke Willemsen Ann Rumley Edoardo Fiorillo Anton J M de Craen Anne Grotevendt Robert Scott Kent D Taylor Graciela E Delgado Jie Yao Annette Kifley Charles Kooperberg Rehan Qayyum Lorna M Lopez Tina L Berentzen Katri Räikkönen Massimo Mangino Stefania Bandinelli Patricia A Peyser Sarah Wild David-Alexandre Trégouët Alan F Wright Jonathan Marten Tatijana Zemunik Alanna C Morrison Bengt Sennblad Geoffrey Tofler Moniek P M de Maat Eco J C de Geus Gordon D Lowe Magdalena Zoledziewska Naveed Sattar Harald Binder Uwe Völker Melanie Waldenberger Kay-Tee Khaw Barbara Mcknight Jie Huang Nancy S Jenny Elizabeth G Holliday Lihong Qi Mark G Mcevoy Diane M Becker John M Starr Antti-Pekka Sarin Pirro G Hysi Dena G Hernandez Min A Jhun Harry Campbell Anders Hamsten Fernando Rivadeneira Wendy L Mcardle P Eline Slagboom Tanja Zeller Wolfgang Koenig Bruce M Psaty Talin Haritunians Jingmin Liu Aarno Palotie André G Uitterlinden David J Stott Albert Hofman Oscar H Franco Ozren Polasek Igor Rudan Pierre-Emmanuel Morange James F Wilson Sharon L R Kardia Luigi Ferrucci Tim D Spector Johan G Eriksson Torben Hansen Ian J Deary Lewis C Becker Rodney J Scott Paul Mitchell Winfried März Nick J Wareham Annette Peters Andreas Greinacher Philipp S Wild J Wouter Jukema Dorret I Boomsma Caroline Hayward Francesco Cucca Russell Tracy Hugh Watkins Alex P Reiner Aaron R Folsom Paul M Ridker Christopher J O'Donnell Nicholas L Smith David P Strachan Abbas Dehghan

Hum Mol Genet 2016 Jan 10;25(2):358-70. Epub 2015 Nov 10.

Department of Epidemiology,

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http://hmg.oxfordjournals.org/content/early/2015/12/08/hmg.d
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http://www.hmg.oxfordjournals.org/lookup/doi/10.1093/hmg/ddv
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http://dx.doi.org/10.1093/hmg/ddv454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715256PMC
January 2016

Gene expression patterns underlying parasite-induced alterations in host behaviour and life history.

Mol Ecol 2016 01 19;25(2):648-60. Epub 2016 Jan 19.

Evolutionary Biology, Johannes Gutenberg University Mainz, Johannes-von-Müller-Weg 6, 55128, Mainz, Germany.

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http://dx.doi.org/10.1111/mec.13498DOI Listing
January 2016

Genome-wide significant association with seven novel multiple sclerosis risk loci.

J Med Genet 2015 Dec 16;52(12):848-55. Epub 2015 Oct 16.

Platform for Genome Analytics, Institutes of Neurogenetics & Integrative and Experimental Genomics, University of Lübeck, Lübeck, Germany Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany Department of Medicine, School of Public Health, Imperial College London, London, UK.

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http://dx.doi.org/10.1136/jmedgenet-2015-103442DOI Listing
December 2015

Large platelets but not putative endothelial progenitor cells are associated with low strut coverage after drug-eluting stent implantation.

Int J Cardiol 2015 Nov 29;199:358-65. Epub 2015 Jul 29.

Universitäts-Herzzentrum Freiburg • Bad Krozingen, Klinik für Kardiologie und Angiologie II, Südring 15, D-79189 Bad Krozingen, Germany.

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http://dx.doi.org/10.1016/j.ijcard.2015.07.062DOI Listing
November 2015

Alterations in circulating miRNA levels following early-stage estrogen receptor-positive breast cancer resection in post-menopausal women.

PLoS One 2014 8;9(7):e101950. Epub 2014 Jul 8.

Department of Oncology, Odense University Hospital and University of Southern Denmark, Odense, Denmark; Department of Cancer and Inflammation, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.

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https://pdfs.semanticscholar.org/c1b5/328439ea2fb3b0610afe1d
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http://dx.plos.org/10.1371/journal.pone.0101950
Publisher Site
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0101950PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086980PMC
October 2015

A weighting approach for judging the effect of patient strata on high-dimensional risk prediction signatures.

BMC Bioinformatics 2015 Sep 15;16:294. Epub 2015 Sep 15.

Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center Mainz, Johannes Gutenberg-University Mainz, Obere Zahlbacher Strasse 69, Mainz, Germany.

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http://dx.doi.org/10.1186/s12859-015-0716-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572441PMC
September 2015

Prevalence, Phenotype, and Psychosocial Well-Being in Euthyroid/Hypothyroid Thyroid-Associated Orbitopathy.

Thyroid 2015 Aug 4;25(8):942-8. Epub 2015 Jun 4.

4 Department of Medicine I, Johannes Gutenberg University Medical Center , Mainz, Germany .

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https://www.liebertpub.com/doi/10.1089/thy.2015.0031
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August 2015

On stability issues in deriving multivariable regression models.

Biom J 2015 Jul 15;57(4):531-55. Epub 2014 Dec 15.

Institut für Medizinische Biometrie, Epidemiologie und Informatik, Universitätsmedizin der Johannes-Gutenberg-Universität Mainz, Obere Zahlbacher Straße 69, 55131, Mainz, Germany.

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http://dx.doi.org/10.1002/bimj.201300222DOI Listing
July 2015

Genetic Cell Ablation Reveals Clusters of Local Self-Renewing Microglia in the Mammalian Central Nervous System.

Immunity 2015 Jul 7;43(1):92-106. Epub 2015 Jul 7.

Institute for Molecular Medicine, University Medical Center of the Johannes Gutenberg-University Mainz, Obere Zahlbacher Str. 67, 55131 Mainz, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2015.06.012DOI Listing
July 2015

[Follow-up after acute pulmonary embolism. A prospective non-interventional multi-center cohort study (FOCUS)].

Dtsch Med Wochenschr 2015 Jun 11;140 Suppl 1:S20-1. Epub 2015 Jun 11.

Institut für Medizinische Biometrie, Epidemiologie und Informatik, Universitätsmedizin Mainz.

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-101767
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June 2015

Impact of Parkinson's disease risk loci on age at onset.

Mov Disord 2015 May 25;30(6):847-50. Epub 2015 Apr 25.

Platform for Genome Analytics, Institutes of Neurogenetics & Integrative and Experimental Genomics, University of Lübeck, Lübeck, Germany.

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http://dx.doi.org/10.1002/mds.26237DOI Listing
May 2015

The prevalence of amblyopia in Germany: data from the prospective, population-based Gutenberg Health Study.

Dtsch Arztebl Int 2015 May;112(19):338-44

Department of Ophthalmology at the University Medical Center of the Johannes Gutenberg University Mainz, Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI) at the University Medical Center of the Johannes Gutenberg University Mainz, Department of Germany Preventive Cardiology and Preventive Medicine, Center for Thrombosis and Hemostasis, German Center for Cardiovascular Disease (DZHK) at the University Medical Center of the Johannes Gutenberg University Mainz.

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http://dx.doi.org/10.3238/arztebl.2015.0338DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458790PMC
May 2015

Simulating recurrent event data with hazard functions defined on a total time scale.

BMC Med Res Methodol 2015 Mar 8;15:16. Epub 2015 Mar 8.

Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center Johannes Gutenberg University Mainz, Obere Zahlbacher Str. 69, Mainz, 55131, Germany.

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http://dx.doi.org/10.1186/s12874-015-0005-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387664PMC
March 2015

Big data in medical science--a biostatistical view.

Dtsch Arztebl Int 2015 Feb;112(9):137-42

Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI) at the University Medical Center of the Johannes Gutenberg University Mainz.

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http://dx.doi.org/10.3238/arztebl.2015.0137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381554PMC
February 2015

Morphology and Progression in Primary Varicose Vein Disorder Due to 677C>T and 1298A>C Variants of MTHFR.

EBioMedicine 2015 Feb 15;2(2):158-64. Epub 2015 Jan 15.

Institute of Human Genetics, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.

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http://dx.doi.org/10.1016/j.ebiom.2015.01.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484817PMC
February 2015

Nighttime aircraft noise impairs endothelial function and increases blood pressure in patients with or at high risk for coronary artery disease.

Clin Res Cardiol 2015 Jan 22;104(1):23-30. Epub 2014 Aug 22.

2 Medical Clinic, Cardiology, University Medical Center Mainz, Johannes Gutenberg University, Langenbeckstrasse 1, 55131, Mainz, Germany.

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http://link.springer.com/10.1007/s00392-014-0751-x
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300412PMC
January 2015

Translating bioinformatics in oncology: guilt-by-profiling analysis and identification of KIF18B and CDCA3 as novel driver genes in carcinogenesis.

Bioinformatics 2015 Jan 18;31(2):216-24. Epub 2014 Sep 18.

Department of Medicine I, University of Regensburg, 93053, Regensburg, Department of Medicine I, Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center, Johannes Gutenberg University, 55131, Mainz, Department of Pathology, University of Heidelberg, 69120, Germany and Laboratory of Experimental Carcinogenesis, National Cancer Institute, National Institutes of Health, Bethesda, 20892 MD, USA.

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http://dx.doi.org/10.1093/bioinformatics/btu586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287940PMC
January 2015

Visualizing inconsistency in network meta-analysis by independent path decomposition.

BMC Med Res Methodol 2014 Dec 16;14:131. Epub 2014 Dec 16.

Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center Johannes Gutenberg University Mainz, Langenbeckstr, 1, 55101 Mainz, Germany.

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http://dx.doi.org/10.1186/1471-2288-14-131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279676PMC
December 2014

Quality of life in Parkinson's disease patients with motor fluctuations and dyskinesias in five European countries.

Parkinsonism Relat Disord 2014 Sep 10;20(9):969-74. Epub 2014 Jun 10.

Department of Epidemiology, Helmholtz Centre for Infection Research, Braunschweig, Germany; Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1016/j.parkreldis.2014.06.001DOI Listing
September 2014

What subject matter questions motivate the use of machine learning approaches compared to statistical models for probability prediction?

Authors:
Harald Binder

Biom J 2014 Jul 25;56(4):584-7. Epub 2014 Feb 25.

Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center, Johannes Gutenberg University Mainz, 55101 Mainz, Germany.

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http://dx.doi.org/10.1002/bimj.201300218DOI Listing
July 2014

Novel circulating microRNA signature as a potential non-invasive multi-marker test in ER-positive early-stage breast cancer: a case control study.

Mol Oncol 2014 Jul 16;8(5):874-83. Epub 2014 Mar 16.

Department of Oncology, Odense University Hospital, Odense, Denmark; University of Southern Denmark, Odense, Denmark; Department of Cancer and Inflammation, Institute of Molecular Medicine, University of Southern Denmark, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.molonc.2014.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528529PMC
July 2014

Early retirement in cancer patients with or without comorbid mental health conditions: a prospective cohort study.

Cancer 2014 Jul 18;120(14):2199-206. Epub 2014 Apr 18.

Institute of Medical Biostatistics, Epidemiology, and Informatics, University Medical Center, Mainz, Germany; Division of Psychosocial Oncology, University of Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.1002/cncr.28716DOI Listing
July 2014

Potential prognostic factors predicting secondary amputation in third-degree open lower limb fractures.

J Trauma Acute Care Surg 2014 Apr;76(4):1076-81

From the University Clinic of Trauma Surgery, General Hospital (A.F., H.B., J.K., S.H.), and Section for Clinical Biometrics (M.M.), Center for Medical Statistics, Informatics and Intelligent Systems, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1097/TA.0000000000000154DOI Listing
April 2014