Publications by authors named "Haralabos P Kalofonos"

100Publications

NF-κB2 and RELB offer prognostic information in colorectal cancer and NFKB2 rs7897947 represents a genetic risk factor for disease development.

Transl Oncol 2020 Oct 15;14(1):100912. Epub 2020 Oct 15.

Clinical and Molecular Oncology Laboratory, Division of Oncology, Department of Medicine, Medical School, University of Patras, Patras, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.tranon.2020.100912DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568186PMC
October 2020

The Fire Within: NF-κB Involvement in Non-Small Cell Lung Cancer.

Cancer Res 2020 Oct 2;80(19):4025-4036. Epub 2020 Jul 2.

Clinical and Molecular Oncology Laboratory, Division of Oncology, Department of Internal Medicine, Medical School, University of Patras, Patras, Greece.

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http://dx.doi.org/10.1158/0008-5472.CAN-19-3578DOI Listing
October 2020

Real world, open label experience with lacosamide against acute painful oxaliplatin-induced peripheral neurotoxicity.

J Peripher Nerv Syst 2020 06 29;25(2):178-183. Epub 2020 Apr 29.

Department of Medicine, Division of Oncology, Medical School, University of Patras, Patras, Greece.

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http://dx.doi.org/10.1111/jns.12374DOI Listing
June 2020

Incidence and characteristics of neurotoxicity in immune checkpoint inhibitors with focus on neuromuscular events: Experience beyond the clinical trials.

J Peripher Nerv Syst 2020 06 24;25(2):171-177. Epub 2020 Mar 24.

Department of Medicine, Division Oncology, Medical School, University Hospital of Patras, Rion-Patras, Greece.

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http://dx.doi.org/10.1111/jns.12371DOI Listing
June 2020

Liability of the voltage-gated potassium channel KCNN3 repeat polymorphism to acute oxaliplatin-induced peripheral neurotoxicity.

J Peripher Nerv Syst 2019 12 16;24(4):298-303. Epub 2019 Oct 16.

Department of Medicine, Division of Oncology, Clinical and Molecular Oncology Laboratory, University of Patras, Rion-Patras, Greece.

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http://dx.doi.org/10.1111/jns.12347DOI Listing
December 2019

Assessing risk factors of falls in cancer patients with chemotherapy-induced peripheral neurotoxicity.

Support Care Cancer 2020 Apr 5;28(4):1991-1995. Epub 2019 Aug 5.

Department of Medicine-Division of Oncology, University Hospital, University of Patras Medical School, Rion, 26504, Patras, Greece.

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http://dx.doi.org/10.1007/s00520-019-05023-5DOI Listing
April 2020

The Impact of Anti-tumor Agents on ER-Positive MCF-7 and HER2-Positive SKBR-3 Breast Cancer Cells Biomechanics.

Ann Biomed Eng 2019 Aug 16;47(8):1711-1724. Epub 2019 May 16.

Laboratory of Biomechanics and Biomedical Engineering, Department of Mechanical Engineering and Aeronautics, University of Patras, Rion, 26504, Patra, Greece.

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http://dx.doi.org/10.1007/s10439-019-02284-3DOI Listing
August 2019

Development of a validated LC-MS/MS method for the in vitro and in vivo quantitation of sunitinib in glioblastoma cells and cancer patients.

J Pharm Biomed Anal 2019 Feb 14;164:690-697. Epub 2018 Nov 14.

Section of Organic Chemistry and Biochemistry, Department of Chemistry, University of Ioannina, 45110, Ioannina, Greece; Cancer Biobank Center and Department of Hematology, School of Medicine, University of Ioannina, 45110, Ioannina, Greece. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S07317085183204
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http://dx.doi.org/10.1016/j.jpba.2018.11.030DOI Listing
February 2019

Development of a novel conjugatable sunitinib analogue validated through in vitro and in vivo preclinical settings.

J Chromatogr B Analyt Technol Biomed Life Sci 2018 Aug 2;1092:515-523. Epub 2018 Jun 2.

Department of Pharmacy, Laboratory of Pharmacokinetics, University of Patras, Patras, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.jchromb.2018.05.050DOI Listing
August 2018

Correction to: Identification of novel human RANK isoforms generated through alternative splicing. Implications in breast cancer cell survival and migration.

Breast Cancer Res 2018 06 7;20(1):47. Epub 2018 Jun 7.

Clinical and Molecular Oncology Laboratory, Division of Oncology, Department of Medicine, University of Patras, 26504, Rion, Greece.

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http://dx.doi.org/10.1186/s13058-018-0985-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992654PMC
June 2018

RANK-c attenuates aggressive properties of ER-negative breast cancer by inhibiting NF-κB activation and EGFR signaling.

Oncogene 2018 09 29;37(37):5101-5114. Epub 2018 May 29.

Clinical and Molecular Oncology Laboratory, Division of Oncology, Department of Medicine, University of Patras, Patras, Greece.

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http://dx.doi.org/10.1038/s41388-018-0324-yDOI Listing
September 2018

Risk stratification of oxaliplatin induced peripheral neurotoxicity applying electrophysiological testing of dorsal sural nerve.

Support Care Cancer 2018 Sep 29;26(9):3143-3151. Epub 2018 Mar 29.

Experimental Neurology Unit, School of Medicine and Surgery, University of Milano-Bicocca, U8 Building, 1st Floor, Room 1.10, Via Cadore, 48, 20900, Monza, MB, Italy.

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http://dx.doi.org/10.1007/s00520-018-4170-9DOI Listing
September 2018

LIMK/cofilin pathway and Slingshot are implicated in human colorectal cancer progression and chemoresistance.

Virchows Arch 2018 May 19;472(5):727-737. Epub 2018 Jan 19.

Department of Anatomy-Histology-Embryology, Medical School, University of Patras, 26500, Patras, Greece.

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http://dx.doi.org/10.1007/s00428-018-2298-0DOI Listing
May 2018

RANK and EGFR in invasive breast carcinoma.

Cancer Genet 2017 Oct 26;216-217:61-66. Epub 2017 Jul 26.

Clinical and Molecular Oncology Laboratory, Division of Oncology, School of Medicine, University of Patras, 26504, Greece.

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http://dx.doi.org/10.1016/j.cancergen.2017.07.004DOI Listing
October 2017

Oxaliplatin-Induced Peripheral Neuropathy and Identification of Unique Severity Groups in Colorectal Cancer.

J Pain Symptom Manage 2017 11 23;54(5):701-706.e1. Epub 2017 Jul 23.

Department of Pain and Translational Symptom Science, School of Nursing, University of Maryland, Baltimore, Maryland, USA; Program in Oncology, University of Maryland School of Medicine, Baltimore, Maryland, USA; UM Center to Advance Chronic Pain Research, University of Maryland, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1016/j.jpainsymman.2017.07.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659746PMC
November 2017

Follicle-Stimulating Hormone Receptor (FSHR): A Promising Tool in Oncology?

Mol Diagn Ther 2016 12;20(6):523-530

Department of Medical Oncology, University Hospital of Patra, Rio, Greece.

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http://dx.doi.org/10.1007/s40291-016-0218-zDOI Listing
December 2016

Lack of association of the M129V polymorphism of the PRNP gene with pseudoexfoliation syndrome.

Clin Ophthalmol 2016 22;10:731-4. Epub 2016 Apr 22.

Department of Ophthalmology, School of Medicine, University of Patras, Rion, Greece.

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http://dx.doi.org/10.2147/OPTH.S92174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853150PMC
May 2016

Identification of a seasonal pattern to brain metastases.

Neuropsychiatr Dis Treat 2016 7;12:609-10. Epub 2016 Mar 7.

Department of Radiation Oncology, University Hospital, Patras Medical School, Rion, Patras, Greece.

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https://www.dovepress.com/identification-of-a-seasonal-patte
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http://dx.doi.org/10.2147/NDT.S104261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788357PMC
March 2016

Early-Stage Breast Cancer in the Elderly: Confronting an Old Clinical Problem.

J Breast Cancer 2015 Sep 24;18(3):207-17. Epub 2015 Sep 24.

Division of Oncology, Department of Medicine, University of Patras Medical School, Patras, Greece.

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http://dx.doi.org/10.4048/jbc.2015.18.3.207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600684PMC
September 2015

Variant of BCL3 gene is strongly associated with five-year survival of non-small-cell lung cancer patients.

Lung Cancer 2015 Sep 20;89(3):311-9. Epub 2015 Jun 20.

Molecular Oncology Laboratory, Division of Oncology, Department of Internal Medicine, Medical School, University of Patras, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2015.06.006DOI Listing
September 2015

Focal Adhesion Proteins α- and β-Parvin are Overexpressed in Human Colorectal Cancer and Correlate with Tumor Progression.

Cancer Invest 2015 26;33(8):387-97. Epub 2015 Jun 26.

b Molecular Oncology Laboratory, School of Medicine , University of Patras , Rio , Patras , Greece.

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http://dx.doi.org/10.3109/07357907.2015.1047508DOI Listing
April 2016

Regioselective chemical and rapid enzymatic synthesis of a novel redox – Antiproliferative molecular hybrid.

Eur J Med Chem 2015 2;96:47-57. Epub 2015 Apr 2.

Section of Organic Chemistry and Biochemistry, Department of Chemistry, University of Ioannina, Ioannina, 45110, Greece; Cancer Biobank Center, University of Ioannina, Ioannina, 45110, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2015.03.064DOI Listing
February 2016

Current therapeutic leads for the treatment of melanoma: targeted immunotherapy in the post-genomic era.

Curr Mol Pharmacol 2014 ;7(1):33-43

Department of Pathology, Patras General Hospital, and Clinical and Molecular Oncology Laboratory, Division of Oncology, Department of Medicine, University of Patras, Patras, Greece.

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http://dx.doi.org/10.2174/187446720701150105171803DOI Listing
September 2015

Bortezomib-induced peripheral neurotoxicity: an update.

Arch Toxicol 2014 Sep 29;88(9):1669-79. Epub 2014 Jul 29.

Department of Neurology, "Saint Andrew's" State General Hospital of Patras, 26335, Patras, Greece,

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http://dx.doi.org/10.1007/s00204-014-1316-5DOI Listing
September 2014

Physicians' brain drain in Greece: a perspective on the reasons why and how to address it.

Health Policy 2014 Aug 12;117(2):210-5. Epub 2014 Apr 12.

Department of Medicine-Division of Oncology, University Hospital of Patras, Rion-Patras, Greece.

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http://dx.doi.org/10.1016/j.healthpol.2014.03.014DOI Listing
August 2014

Chemotherapy-induced peripheral neuropathy in adults: a comprehensive update of the literature.

Cancer Manag Res 2014 19;6:135-47. Epub 2014 Mar 19.

Department of Medicine-Division of Oncology, University of Patras Medical School, Rion-Patras, Greece.

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http://dx.doi.org/10.2147/CMAR.S44261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964029PMC
June 2014

The combination of antitumor drugs, exemestane and erlotinib, induced resistance mechanism in H358 and A549 non-small cell lung cancer (NSCLC) cell lines.

Pharm Biol 2013 Nov 5. Epub 2013 Nov 5.

Clinical Oncology Laboratory, University Hospital of Patras, Patras Medical School , Rion , Greece and.

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http://dx.doi.org/10.3109/13880209.2013.841718DOI Listing
November 2013

The exposure of breast cancer cells to fulvestrant and tamoxifen modulates cell migration differently.

Biomed Res Int 2013 2;2013:147514. Epub 2013 Jul 2.

Clinical Oncology Laboratory, Division of Oncology, Department of Medicine, University of Patras, Patras Medical School, 26504 Rio, Greece.

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http://dx.doi.org/10.1155/2013/147514DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713599PMC
March 2014

Expression of syndecan-4 and correlation with metastatic potential in testicular germ cell tumours.

Biomed Res Int 2013 15;2013:214864. Epub 2013 Jun 15.

Hematology Division, Department of Internal Medicine, University Hospital of Patras, 26500 Patras, Greece.

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http://dx.doi.org/10.1155/2013/214864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3697279PMC
February 2014

Voltage-gated sodium channel polymorphisms play a pivotal role in the development of oxaliplatin-induced peripheral neurotoxicity: results from a prospective multicenter study.

Cancer 2013 Oct 2;119(19):3570-7. Epub 2013 Jul 2.

Department of Neurology, "Saint Andrew's" General Hospital of Patras, Patras, Greece; Laboratory of Molecular Oncology, Division of Oncology, Department of Medicine, University Hospital of Patras, Rion-Patras, Greece.

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http://dx.doi.org/10.1002/cncr.28234DOI Listing
October 2013

Early predictors of oxaliplatin-induced cumulative neuropathy in colorectal cancer patients.

J Neurol Neurosurg Psychiatry 2014 Apr 29;85(4):392-8. Epub 2013 Jun 29.

Unit of Neuro-Oncology, Hospital Universitari de Bellvitge-ICO Duran i Reynals, , Barcelona, Spain.

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http://dx.doi.org/10.1136/jnnp-2013-305334DOI Listing
April 2014

Financial crisis and austerity measures in Greece: their impact on health promotion policies and public health care.

Health Policy 2013 Nov 19;113(1-2):8-12. Epub 2013 Jun 19.

Department of Educational Sciences and Early Childhood Education, University of Patras, Rion, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.healthpol.2013.05.017DOI Listing
November 2013

Comparative study and meta-analysis of meta-analysis studies for the correlation of genomic markers with early cancer detection.

Hum Genomics 2013 Jun 5;7:14. Epub 2013 Jun 5.

Faculty of Mathematical, Physical and Natural Sciences, Department of Biological Sciences, University of Trieste, Trieste, 34128, Italy.

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http://dx.doi.org/10.1186/1479-7364-7-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686617PMC
June 2013

Alternative splicing generates a truncated isoform of human TNFRSF11A (RANK) with an altered capacity to activate NF-κB.

Gene 2013 Aug 7;525(1):124-9. Epub 2013 May 7.

Clinical and Molecular Oncology Laboratory, Division of Oncology, School of Medicine, University of Patras, Greece.

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https://linkinghub.elsevier.com/retrieve/pii/S03781119130057
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http://dx.doi.org/10.1016/j.gene.2013.04.075DOI Listing
August 2013

NSCLC and the alternative pathway of NF-κB: uncovering an unknown relation.

Virchows Arch 2012 May 5;460(5):515-23. Epub 2012 May 5.

Molecular Oncology Laboratory, Division of Oncology, Department of Internal Medicine, Medical School, University of Patras, Patras, Greece.

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http://dx.doi.org/10.1007/s00428-012-1230-2DOI Listing
May 2012

Angiogenesis as a therapeutic target in breast cancer.

Mini Rev Med Chem 2012 Oct;12(12):1230-8

Division of Oncology, Department of Medicine, University Hospital of Patras, Rion, Greece.

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http://dx.doi.org/10.2174/138955712802761988DOI Listing
October 2012

Assessment of sexual function in patients with cancer undergoing radiotherapy--a single centre prospective study.

Anticancer Res 2012 Feb;32(2):657-64

Department of Radiation Oncology, University of Patras Medical School, 26504, Rion, Patras, Greece.

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February 2012

Prognostic significance of Dicer cellular levels in soft tissue sarcomas.

Cancer Invest 2012 Feb 13;30(2):172-9. Epub 2011 Dec 13.

Department of Anatomy-Histology-Embryology, Unit of Bone and Soft Tissue Studies, School of Medicine, University of Patras, Patras, Greece.

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http://dx.doi.org/10.3109/07357907.2011.633293DOI Listing
February 2012

Altered expression of NFY-C and RORA in colorectal adenocarcinomas.

Acta Histochem 2012 Oct 21;114(6):553-61. Epub 2011 Nov 21.

Molecular Oncology Laboratory, Division of Oncology, Department of Medicine, Medical School, University of Patras, Greece.

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http://linkinghub.elsevier.com/retrieve/pii/S006512811100157
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http://dx.doi.org/10.1016/j.acthis.2011.10.005DOI Listing
October 2012

Expression of the ribonucleases Drosha, Dicer, and Ago2 in colorectal carcinomas.

Virchows Arch 2011 Oct 18;459(4):431-40. Epub 2011 Jul 18.

Department of Clinical Oncology, University of Patras, School of Medicine, Patras, Greece.

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http://dx.doi.org/10.1007/s00428-011-1119-5DOI Listing
October 2011

Epothilone-induced peripheral neuropathy: a review of current knowledge.

J Pain Symptom Manage 2011 Dec 31;42(6):931-40. Epub 2011 May 31.

Department of Neurology, Saint Andrew's State General Hospital of Patras, Patras, Greece.

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http://dx.doi.org/10.1016/j.jpainsymman.2011.02.022DOI Listing
December 2011

Association of FOXP3 expression with non-small cell lung cancer.

Anticancer Res 2011 May;31(5):1677-83

Molecular Oncology Laboratory, Division of Oncology, Department of Medicine, Medical School, University of Patras, Greece.

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May 2011

Ionizing radiation affects epidermal growth factor receptor signalling and metalloproteinase secretion in glioma cells.

Cancer Genomics Proteomics 2011 Jan-Feb;8(1):33-8

Department of Radiation Oncology, University of Patras Medical School, University Campus, 26504 Patras, Greece.

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April 2011

Vitamin E for preventing chemotherapy-induced peripheral neuropathy.

Support Care Cancer 2011 May 14;19(5):725-6; author reply 727-8. Epub 2011 Jan 14.

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http://dx.doi.org/10.1007/s00520-011-1090-3DOI Listing
May 2011

Promises and hurdles of undergraduate medical development in Greece.

Adv Med Educ Pract 2011 26;2:201-8. Epub 2011 Sep 26.

Department of Educational Sciences and Early Childhood Education, University of Patras, Rio, Patras, Greece.

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http://dx.doi.org/10.2147/AMEP.S25200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661258PMC
June 2013

The effects of anti-VEGFR and anti-EGFR agents on glioma cell migration through implication of growth factors with integrins.

Anticancer Res 2010 Dec;30(12):4987-92

Clinical Oncology Laboratory, Division of Oncology, Department of Medicine, University Hospital of Patras, Patras Medical School, Rion, Greece.

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December 2010

Either called "chemobrain" or "chemofog," the long-term chemotherapy-induced cognitive decline in cancer survivors is real.

J Pain Symptom Manage 2011 Jan 15;41(1):126-39. Epub 2010 Sep 15.

Division of Oncology, Department of Medicine, University Hospital, University of Patras Medical School, Rion-Patras, Greece.

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http://dx.doi.org/10.1016/j.jpainsymman.2010.04.021DOI Listing
January 2011

Autophagy: novel action of panitumumab in colon cancer.

Anticancer Res 2009 Dec;29(12):5077-82

Clinical Oncology Laboratory, Division of Oncology, Department of Medicine, University Hospital of Patras, Patras Medical School, Rio 26504, Greece.

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December 2009

Bevacizumab in the treatment of breast cancer.

Cancer Treat Rev 2010 Feb 22;36(1):75-82. Epub 2009 Nov 22.

Department of Medicine, University Hospital, Patras Medical School, Rion, Greece.

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http://dx.doi.org/10.1016/j.ctrv.2009.10.007DOI Listing
February 2010

Liability of the voltage-gated sodium channel gene SCN2A R19K polymorphism to oxaliplatin-induced peripheral neuropathy.

Oncology 2009 7;77(3-4):254-6. Epub 2009 Sep 7.

Division of Clinical Oncology, Department of Medicine, University Hospital of Patras, Rion-Patras, Greece.

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https://www.karger.com/Article/FullText/236049
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http://dx.doi.org/10.1159/000236049DOI Listing
October 2009

An in vitro study, evaluating the effect of sunitinib and/or lapatinib on two glioma cell lines.

Invest New Drugs 2010 Oct 15;28(5):554-60. Epub 2009 Jul 15.

Clinical Oncology Laboratory, Division of Oncology, Department of Medicine, University Hospital of Patras, Patras Medical School, Rion, 26504, Greece.

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http://dx.doi.org/10.1007/s10637-009-9290-0DOI Listing
October 2010

The upgraded role of HER3 and HER4 receptors in breast cancer.

Crit Rev Oncol Hematol 2010 May 30;74(2):73-8. Epub 2009 May 30.

Department of Medicine, University Hospital of Patras, Rion, Greece.

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http://linkinghub.elsevier.com/retrieve/pii/S104084280900102
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http://dx.doi.org/10.1016/j.critrevonc.2009.04.011DOI Listing
May 2010

Angiogenesis and anti-angiogenic molecularly targeted therapies in malignant gliomas.

Oncology 2009 12;77(1):1-11. Epub 2009 May 12.

Department of Medicine, Division of Clinical Oncology, University Hospital, University of Patras Medical School, Rion-Patras, Greece.

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http://dx.doi.org/10.1159/000218165DOI Listing
July 2009

Recent advances relating to the clinical application of naked monoclonal antibodies in solid tumors.

Mol Med 2009 May-Jun;15(5-6):183-91. Epub 2009 Feb 17.

Department of Medicine-Division of Clinical Oncology, University Hospital, University of Patras Medical School, Rion-Patras, Greece.

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http://dx.doi.org/10.2119/molmed.2009.00007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2622734PMC
September 2009

Molecularly targeted therapies for malignant gliomas.

Mol Med 2009 Mar-Apr;15(3-4):115-22

Department of Medicine, Division of Clinical Oncology, University Hospital, University of Patras Medical School, Rion-Patras, Greece.

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http://dx.doi.org/10.2119/molmed.2008.00123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646824PMC
April 2009

Dual targeting of EGFR and HER-2 in colon cancer cell lines.

Cancer Chemother Pharmacol 2009 May 27;63(6):973-81. Epub 2008 Aug 27.

Clinical Oncology Laboratory, Division of Oncology, Department of Medicine, University Hospital of Patras, Patras Medical School, 26504, Rio, Greece.

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http://dx.doi.org/10.1007/s00280-008-0820-9DOI Listing
May 2009

Religiosity and its relation to quality of life in Christian Orthodox cancer patients undergoing chemotherapy.

Psychooncology 2009 Mar;18(3):284-9

Department of Psychiatry, University of Patras Medical School, University Hospital, Rion, Greece.

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http://dx.doi.org/10.1002/pon.1402DOI Listing
March 2009